Hub : Genes

B3gntl1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr10:106880723:106881068 0.03 0.02 6.3e-04 0.03 0.02 0.02 0.01 1.7e-04 3.1e-03 5.0e-03 1.5e-02
2 Adipose mRNA stability ENSRNOG00000049724 0.04 0.03 2.0e-04 0.03 0.03 0.04 0.04 4.4e-04 3.0e-04 6.0e-05 4.1e-05
3 BLA gene expression ENSRNOG00000049724 0.1 0.05 8.8e-06 0.11 0.11 0.09 0.11 1.8e-06 2.0e-06 2.8e-05 2.2e-06
4 BLA mRNA stability ENSRNOG00000049724 0.12 0.07 2.3e-04 0.04 0.06 0.07 0.06 2.4e-03 3.1e-04 1.3e-04 2.5e-04
5 Brain gene expression ENSRNOG00000049724 0.02 0.01 3.2e-03 0.04 0.03 0.01 0 6.3e-05 1.5e-03 1.5e-02 1.0e-01
6 Brain intron excision ratio chr10:106880723:106881068 0.09 0.05 3.3e-09 0.11 0.1 0.1 0.1 3.8e-10 2.6e-09 1.0e-09 9.5e-10
7 Brain intron excision ratio chr10:106880882:106881068 0.07 0.04 8.5e-06 0.07 0.06 0.05 0.06 6.2e-07 7.0e-06 1.5e-05 7.8e-06
8 Brain mRNA stability ENSRNOG00000049724 0.07 0.04 7.9e-08 0.09 0.07 0.07 0.03 1.2e-08 6.2e-07 4.2e-07 1.3e-03
9 Liver gene expression ENSRNOG00000049724 0.07 0.03 1.1e-09 0.09 0.09 0.07 0.09 1.8e-10 5.8e-10 7.5e-08 4.9e-10
10 NAcc gene expression ENSRNOG00000049724 0.06 0.04 2.2e-05 0.08 0 0.05 0.02 2.3e-06 1.8e-01 8.3e-05 1.1e-02
11 NAcc intron excision ratio chr10:106880723:106881068 0.04 0.02 5.1e-04 0.06 0.03 0.04 0.01 2.5e-05 5.1e-03 9.1e-04 4.5e-02
12 NAcc mRNA stability ENSRNOG00000049724 0.04 0.03 2.4e-03 0.02 0.02 0.01 0 1.4e-02 9.5e-03 6.9e-02 2.8e-01
13 PL gene expression ENSRNOG00000049724 0.14 0.06 7.6e-11 0.15 0.15 0.16 0.09 1.6e-11 9.2e-12 2.1e-12 1.6e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.72.14.4-1.0-1.01.4-2.1-1.8-1.01.0-1.5-1.4-1.6-1.0-1.8-1.8
BMI without tail5.211.014.9-3.3-3.9-2.8-2.8-3.6-3.23.2-3.4-3.4-3.5-3.2-3.5-3.1
Body weight3.313.822.9-3.1-3.70.2-4.8-4.2-3.23.2-3.9-3.6-4.0-3.2-4.4-4.5
Epididymis fat weight0.61.42.0-1.1-1.4-0.3-1.0-1.4-1.11.1-1.4-1.4-1.4-1.1-1.3-1.2
Glucose4.06.112.22.83.52.02.22.42.6-2.62.42.32.42.61.72.4
Heart weight1.72.44.8-1.0-1.10.2-1.8-1.8-1.31.3-1.8-1.6-1.7-1.3-2.2-1.9
Left kidney weight0.51.55.1-0.2-0.72.0-2.2-1.2-0.30.3-1.0-0.8-1.1-0.3-1.4-1.7
Right kidney weight0.51.37.90.2-0.72.8-1.8-0.9-0.20.2-0.9-0.7-0.9-0.2-0.9-1.4
Tail length4.814.620.4-3.8-4.5-4.0-3.0-3.8-3.83.8-3.9-3.9-3.8-3.8-3.9-3.6
Length with tail1.86.69.4-2.1-2.7-0.6-3.1-2.8-2.32.3-2.8-2.6-2.8-2.3-2.9-3.0
Length without tail0.92.012.91.51.63.6-0.50.61.3-1.30.81.10.71.30.40.1
Liver weight, left0.20.41.20.71.01.10.60.30.6-0.60.40.40.40.6-0.10.5
Liver weight, right1.32.23.6-1.3-1.4-0.3-1.8-1.7-1.41.4-1.6-1.2-1.7-1.4-1.9-1.7
Parametrial fat weight1.22.33.4-1.7-1.1-1.6-0.2-1.8-1.61.6-1.7-1.6-1.8-1.6-1.7-1.0
Retroperitoneal fat weight4.013.217.1-3.7-3.8-3.1-3.1-4.0-3.53.5-3.8-3.6-3.8-3.5-4.1-3.6
Intraocular pressure1.21.63.7-1.2-1.9-0.8-1.4-1.3-1.11.1-1.3-1.1-1.3-1.1-1.3-1.5
Extensor digitorum longus weight0.41.53.7-1.1-1.9-0.3-1.6-1.4-0.90.9-1.3-0.9-1.4-0.9-1.1-1.4
Soleus weight1.95.66.9-2.6-2.6-1.8-2.2-2.3-2.42.4-2.4-2.6-2.3-2.4-2.2-2.4
Tibialis anterior weight0.31.02.0-1.1-1.4-1.1-0.9-1.1-0.90.9-1.0-1.0-1.0-0.9-0.8-0.9
Tibia length11.231.454.9-4.9-4.9-0.8-7.4-5.8-5.35.3-5.8-5.7-5.9-5.3-6.3-6.9
Number of licking bursts0.30.30.6-0.6-0.7-0.5-0.3-0.6-0.60.6-0.6-0.7-0.6-0.6-0.3-0.4
Food consumed during 24 hour testing period0.50.61.3-1.0-0.8-1.1-0.5-0.8-0.80.8-0.7-0.7-0.7-0.8-0.5-0.6
Times rat made contact with spout1.61.99.6-1.5-0.4-3.10.1-1.1-1.31.3-1.1-1.4-1.0-1.3-1.1-0.4
Mean time between licks in bursts2.33.23.81.91.61.41.71.91.8-1.81.81.81.91.81.91.8
Mean num. licks in bursts0.20.21.7-0.50.1-1.30.1-0.3-0.30.3-0.2-0.2-0.2-0.3-0.5-0.0
Std. dev. time between licks in bursts0.60.72.8-0.6-1.70.2-0.9-0.6-0.70.7-0.7-0.8-0.7-0.7-0.4-0.9
Water consumed over 24 hours0.10.10.4-0.10.4-0.70.30.10.0-0.00.1-0.10.10.00.30.3
Indifference point 0 sec0.00.00.10.0-0.0-0.30.20.30.1-0.10.2-0.00.30.10.30.1
Indifference point AUC0.10.10.6-0.8-0.2-0.60.4-0.3-0.30.3-0.2-0.3-0.2-0.3-0.30.1
Indifference point function ln k0.71.04.31.30.42.1-0.10.91.0-1.00.70.90.81.01.10.3
Indifference point function log k0.71.04.31.30.42.1-0.10.91.0-1.00.70.90.81.01.10.3
Delay discounting total patch changes 0 sec0.00.00.10.0-0.1-0.10.20.30.1-0.10.20.00.30.10.30.1
Delay discounting total patch changes 12 sec0.20.21.1-0.20.5-0.71.10.30.2-0.20.40.10.40.20.20.7
Delay discounting total patch changes 18 sec0.10.10.20.0-0.2-0.20.40.50.2-0.20.40.30.40.20.40.3
Delay discounting total patch changes 24 sec0.10.10.5-0.7-0.4-0.5-0.2-0.1-0.40.4-0.1-0.4-0.1-0.4-0.3-0.3
Delay discounting total patch changes 6 sec0.20.30.8-0.8-0.2-0.90.0-0.4-0.60.6-0.4-0.7-0.4-0.6-0.5-0.2
Delay discounting time to switch 0 sec0.30.51.01.00.70.00.70.70.7-0.70.70.70.60.70.70.7
Delay discounting water rate 0 sec0.50.71.4-1.1-1.2-0.4-0.5-0.7-0.90.9-0.8-0.9-0.7-0.9-0.7-0.8
Delay discounting water rate 12 sec0.10.21.6-0.0-0.31.3-0.3-0.2-0.10.1-0.3-0.3-0.3-0.1-0.1-0.4
Delay discounting water rate 18 sec0.81.02.5-0.7-1.50.6-1.6-0.8-0.80.8-1.0-0.8-0.9-0.8-0.8-1.3
Delay discounting water rate 24 sec1.21.73.8-0.9-1.90.2-2.0-1.1-1.11.1-1.3-1.1-1.2-1.1-1.2-1.7
Delay discounting water rate 6 sec0.30.44.00.70.12.00.10.40.4-0.40.20.30.30.40.40.0
Locomotor activity0.81.31.91.41.30.71.11.11.2-1.21.11.21.11.21.01.2
Locomotor testing distance0.50.81.61.30.51.00.30.91.1-1.10.81.10.81.10.90.7
Locomotor testing rearing0.81.22.21.00.8-0.31.51.20.9-0.91.11.21.10.91.21.3
Light reinforcement 11.22.13.3-1.5-1.8-1.4-1.2-1.6-1.41.4-1.5-1.7-1.5-1.4-1.1-1.4
Light reinforcement 21.72.22.8-1.5-1.7-1.0-1.4-1.6-1.41.4-1.6-1.5-1.6-1.4-1.5-1.6
Reaction time number correct0.40.53.0-0.5-1.70.2-0.9-0.5-0.50.5-0.6-0.4-0.6-0.5-0.1-0.8
Reaction time mean minus median0.60.81.70.61.1-0.31.30.80.8-0.80.80.90.80.80.61.2
Reaction time mean minus median AUC0.00.10.20.10.3-0.30.40.20.2-0.20.20.20.20.20.20.3
Reaction time num false alarms0.00.00.00.2-0.2-0.0-0.20.00.2-0.20.10.20.00.2-0.0-0.1
Reaction time num false alarms AUC0.10.10.30.50.00.30.20.40.5-0.50.40.50.30.50.40.2
Reaction time trials correct on left0.40.53.0-0.5-1.70.2-0.9-0.5-0.50.5-0.6-0.4-0.6-0.5-0.1-0.8
Reaction time trials on left0.40.53.1-0.5-1.80.2-0.9-0.5-0.50.5-0.6-0.4-0.6-0.5-0.1-0.8
Reaction time mean0.20.30.7-0.6-0.4-0.8-0.2-0.6-0.50.5-0.6-0.7-0.6-0.5-0.6-0.4
Reaction time mean AUC0.40.50.6-0.7-0.8-0.7-0.4-0.7-0.70.7-0.8-0.8-0.8-0.7-0.7-0.6
Median of all reaction times0.30.40.7-0.6-0.6-0.6-0.5-0.7-0.60.6-0.8-0.8-0.7-0.6-0.7-0.6
Reaction time omissions0.10.10.5-0.2-0.1-0.70.50.2-0.10.10.10.10.1-0.10.30.4
Reaction time false alarm rate0.30.40.80.60.9-0.00.60.60.6-0.60.60.70.60.60.40.6
Reaction time premature initiation rate0.70.91.50.91.00.51.20.91.0-1.00.90.70.91.01.21.2
Reaction time premature initiations0.20.30.80.5-0.20.60.50.50.5-0.50.40.40.40.50.90.6
Std. dev. reaction times0.30.40.80.50.6-0.20.90.60.6-0.60.50.60.60.60.50.8
Reaction time trials completed0.40.53.1-0.5-1.80.2-0.9-0.5-0.50.5-0.6-0.4-0.6-0.5-0.1-0.8
Reaction time trials AUC0.40.63.2-0.6-1.80.2-1.0-0.5-0.60.6-0.7-0.5-0.6-0.6-0.2-0.9
Social response proportion1.41.53.31.30.81.80.41.21.3-1.31.11.41.21.31.30.8
Social responses0.50.73.60.90.31.9-0.00.60.8-0.80.60.60.60.81.10.3
Social time0.20.21.70.5-0.11.3-0.60.00.3-0.3-0.00.1-0.00.30.2-0.4
Conditioned locomotion5.76.79.6-2.6-3.1-1.6-2.6-2.7-2.62.6-2.6-2.5-2.6-2.6-2.5-2.8
Cocaine response after cond. corrected0.60.61.30.81.10.40.70.80.8-0.80.80.80.80.80.80.8
Cocaine response after cond. not corrected1.31.51.91.31.40.91.11.21.2-1.21.21.21.21.21.21.2
Cocaine response before conditioning0.50.61.20.90.21.10.70.80.8-0.80.80.80.80.80.80.7
Saline control response2.22.93.7-1.8-1.8-1.3-1.6-1.5-1.91.9-1.6-1.8-1.5-1.9-1.5-1.7
Condit. Reinf. active minus inactive responses2.53.28.3-1.4-2.0-0.1-2.9-1.8-1.51.5-1.7-1.7-1.7-1.5-1.8-2.4
Condit. Reinf. active-inactive response ratio4.14.37.8-1.8-1.8-0.9-2.8-2.2-1.91.9-2.1-2.1-2.1-1.9-2.3-2.5
Condit. Reinf. active responses0.91.24.1-0.8-1.40.1-2.0-1.0-0.80.8-0.9-0.9-1.0-0.8-1.0-1.6
Condit. Reinf. inactive responses0.50.61.00.80.31.00.20.90.8-0.80.90.90.90.80.80.5
Condit. Reinf. lever presses0.30.40.7-0.7-0.8-0.4-0.6-0.6-0.60.6-0.6-0.7-0.6-0.6-0.5-0.6
Condit. Reinf. lever reinforcers received0.81.23.6-0.8-1.4-0.1-1.9-1.0-0.80.8-1.0-0.9-1.0-0.8-1.0-1.5
Pavlov. Cond. lever latency1.01.42.11.21.41.31.21.21.0-1.01.11.01.21.01.21.1
Pavlov. Cond. magazine entry latency1.41.63.11.21.00.31.81.21.3-1.31.31.21.21.31.31.6
Pavlov. Cond. change in total contacts0.00.00.10.3-0.3-0.1-0.30.10.3-0.30.20.30.10.30.1-0.0
Pavlov. Cond. index score0.10.10.20.1-0.1-0.50.50.10.2-0.20.20.20.10.20.10.4
Pavlov. Cond. latency score0.00.00.3-0.0-0.3-0.60.3-0.10.1-0.10.00.0-0.00.1-0.00.2
Pavlov. Cond. lever contacts1.52.03.2-1.6-1.8-1.6-1.3-1.4-1.31.3-1.3-1.3-1.4-1.3-1.4-1.4
Pavlov. Cond. magazine entry number1.31.63.2-1.2-1.0-0.3-1.8-1.2-1.21.2-1.3-1.3-1.2-1.2-1.4-1.6
Pavlov. Cond. intertrial magazine entries2.53.24.8-1.7-2.0-0.7-2.2-1.7-1.81.8-1.7-1.9-1.7-1.8-1.8-2.1
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.30.1-0.50.70.30.4-0.40.40.40.30.40.30.6
Pavlov. Cond. response bias0.10.10.6-0.5-0.6-0.8-0.1-0.4-0.30.3-0.3-0.2-0.3-0.3-0.3-0.2
Conditioned reinforcement - actives0.00.00.1-0.2-0.3-0.20.2-0.0-0.20.20.0-0.1-0.1-0.20.10.1
Conditioned reinforcement - inactives0.10.10.2-0.30.2-0.40.5-0.1-0.40.4-0.4-0.3-0.2-0.4-0.20.2
Conditioned locomotion0.10.10.5-0.1-0.0-0.70.20.4-0.40.40.20.40.2-0.4-0.20.3
Intermittent access intake day 1-15 change0.10.10.6-0.50.0-0.80.70.0-0.20.2-0.3-0.00.0-0.20.10.5
Intermittent access intake escalation0.20.21.2-0.50.0-1.10.90.2-0.30.3-0.10.20.1-0.30.20.7
Intermittent access intake escalation 20.20.21.1-0.40.4-1.10.80.1-0.10.1-0.30.20.0-0.1-0.30.5
Intermitt. access day 1 inactive lever presses0.10.10.30.1-0.3-0.5-0.1-0.10.2-0.2-0.4-0.2-0.10.2-0.2-0.1
Intermitt. access day 15 inactive lever presses0.60.61.2-0.7-1.0-0.9-1.1-0.3-0.80.8-0.4-1.1-0.6-0.8-0.7-0.8
Intermitt. access escalation Index1.71.52.9-1.4-1.7-1.5-1.2-1.2-1.31.3-1.0-1.1-1.0-1.3-0.7-1.1
Intermittent access day 1 total infusions1.01.11.5-0.9-0.9-0.7-1.1-1.1-1.21.2-0.9-1.0-1.1-1.2-1.1-1.0
Intermittent access day 15 total infusions0.50.51.4-1.0-0.6-1.2-0.2-0.5-0.90.9-0.5-0.4-0.5-0.9-0.5-0.2
Intermittent access terminal intake (last 3 days)0.60.62.5-1.0-0.5-1.6-0.1-0.6-1.01.0-0.6-0.5-0.5-1.0-0.6-0.2
Intermittent access total infusions0.60.61.1-1.0-0.8-0.7-0.6-0.7-1.01.0-0.6-0.8-0.7-1.0-0.7-0.5
Intermittent access day 1 locomotion0.00.00.10.2-0.2-0.2-0.40.1-0.00.0-0.00.10.1-0.0-0.1-0.0
Intermittent access day 15 total locomotion0.10.10.7-0.3-0.2-0.8-0.4-0.1-0.30.3-0.2-0.1-0.1-0.3-0.4-0.1
Intermittent access total locomotion0.00.00.10.1-0.1-0.3-0.20.30.1-0.10.00.20.10.1-0.10.1
Intermittent access standard deviation2.62.84.11.82.01.42.01.71.7-1.70.91.71.51.71.61.8
Cocaine induced anxiety0.40.40.9-0.80.6-0.4-0.5-0.8-0.70.7-0.6-0.6-0.5-0.7-0.9-0.6
Post-drug Anxiety0.30.31.20.61.10.50.30.50.6-0.60.30.60.60.60.40.3
Baseline Anxiety3.53.75.52.40.92.11.12.22.2-2.21.81.91.92.22.11.5
Lifetime Intake0.10.10.2-0.4-0.2-0.50.0-0.2-0.50.5-0.1-0.3-0.2-0.5-0.10.0
Incentive Sensitization - Responses0.90.91.8-0.9-1.0-1.3-0.3-1.1-0.70.7-1.2-1.1-1.1-0.7-0.9-0.6
Incentive Sensitization - Breakpoint0.70.71.7-0.8-0.9-1.3-0.2-1.0-0.50.5-1.1-1.0-1.0-0.5-0.9-0.6
Progressive ratio test 1 active lever presses0.50.62.1-0.8-0.7-1.5-0.9-0.5-0.70.7-0.2-0.7-0.4-0.7-0.7-0.5
Progressive ratio test 1 breakpoint1.11.12.9-1.0-1.1-1.7-1.2-0.9-1.01.0-0.7-1.1-0.8-1.0-1.1-0.9
Progressive ratio test 1 inactive lever presses0.80.81.4-1.1-0.8-0.8-1.0-0.6-1.21.2-0.6-0.9-0.6-1.2-0.8-0.7
Progressive ratio test 2 active lever presses0.30.41.5-0.5-0.6-1.2-0.3-0.7-0.30.3-0.6-0.6-0.6-0.3-0.7-0.3
Progressive ratio test 2 breakpoint0.50.51.5-0.6-1.0-1.2-0.4-0.8-0.40.4-0.8-0.8-0.8-0.4-0.7-0.6
Progressive ratio test 2 inactive lever presses0.00.00.2-0.1-0.0-0.3-0.5-0.2-0.00.0-0.1-0.2-0.1-0.0-0.2-0.2
Total sessions with >9 infusions0.20.20.40.60.40.50.20.50.4-0.40.60.60.50.40.50.5
Short access day 1 total inactive lever presses0.00.00.20.1-0.40.3-0.2-0.10.1-0.1-0.1-0.1-0.20.1-0.1-0.1
Short access day 10 total inactive lever presses1.21.33.6-0.7-1.0-0.3-0.8-1.5-0.70.7-1.9-1.4-1.5-0.7-1.0-1.3
Short access day 1 total infusions2.12.23.01.61.61.21.41.41.5-1.51.41.51.41.51.71.5
Short access day 10 total infusions0.20.21.5-0.5-0.1-1.2-0.1-0.3-0.60.6-0.2-0.2-0.3-0.6-0.30.0
Short access total infusions0.10.10.30.10.3-0.20.50.10.1-0.10.20.00.20.10.40.4
Short access day 1 locomotion0.60.61.10.91.10.70.40.70.9-0.90.60.90.70.90.80.7
Short access day 10 total locomotion1.21.32.31.31.50.21.21.21.2-1.20.91.11.21.21.01.2
Short access total locomotion0.90.91.51.21.10.40.61.01.2-1.20.60.91.01.20.90.9
Compulsive drug intake0.90.91.3-0.7-1.0-0.2-0.9-1.1-0.90.9-1.1-1.1-1.1-0.9-0.9-1.1
One hour access (0.3 mA shock)1.61.82.5-1.4-1.2-1.5-0.8-1.5-1.31.3-1.5-1.6-1.5-1.3-1.3-1.1
One hour access (shock baseline)0.60.61.2-1.0-0.8-1.1-0.5-0.8-0.90.9-0.6-0.8-0.8-0.9-0.7-0.5
Number of responses in last shaping day0.20.20.7-0.1-0.20.8-0.7-0.4-0.20.2-0.1-0.2-0.3-0.2-0.4-0.6
Context. condit. distance diff. score0.70.92.3-1.0-1.5-0.8-0.8-1.0-0.90.9-0.9-0.9-0.9-0.9-0.7-0.9
Locomotion velocity, session 12.12.34.51.42.10.91.71.51.4-1.41.51.61.51.41.41.6
Locomotion distance, session 11.01.23.21.20.61.80.41.01.2-1.21.11.21.01.21.20.8
Locomotion velocity, session 24.65.46.42.32.32.12.22.42.3-2.32.42.52.42.32.32.4
Locomotion distance, session 20.10.11.20.1-0.31.1-0.20.10.2-0.20.20.30.20.20.2-0.0
Locomotion velocity, session 33.03.54.11.92.01.91.52.01.9-1.92.01.92.01.91.91.7
Locomotion distance, session 35.05.46.42.42.22.51.92.42.4-2.42.42.22.42.42.42.2
Stereotopy head waving bouts, day 30.20.20.60.50.50.80.10.40.4-0.40.40.40.40.40.30.2
Stereotopy head waving duration, day 30.10.10.40.20.00.6-0.4-0.00.1-0.1-0.10.2-0.10.1-0.2-0.3
Locomotion velocity, session 70.90.91.50.90.80.50.81.11.0-1.01.11.21.01.01.11.0
Locomotion distance, session 73.13.95.41.81.61.22.12.12.0-2.02.12.02.12.02.32.2
Stereotopy head waving bouts, day 70.80.92.0-0.6-0.90.0-1.4-1.1-0.80.8-1.0-0.9-1.1-0.8-1.2-1.2
Stereotopy head waving duration, day 70.91.12.4-0.8-1.1-0.0-1.6-1.1-0.90.9-1.1-1.0-1.2-0.9-1.2-1.4
Locomotion velocity, session 80.20.31.80.3-0.41.3-0.80.30.3-0.30.30.30.40.30.4-0.3
Locomotion distance, session 80.71.13.9-0.9-2.00.3-1.4-1.0-0.90.9-0.9-0.8-1.0-0.9-0.8-1.2
Degree of sensitization distance0.90.93.2-1.1-1.0-1.8-0.2-0.8-0.90.9-0.8-0.7-0.8-0.9-0.7-0.5
Degree of sensitization stereotypy0.80.91.7-0.7-1.00.1-1.3-1.1-0.80.8-1.0-0.9-1.1-0.8-1.1-1.2
Condit. Reinf. active minus inactive responses2.62.93.5-1.7-1.8-1.2-1.9-1.7-1.71.7-1.7-1.7-1.7-1.7-1.7-1.9
Condit. Reinf. active-inactive response ratio1.21.33.7-0.9-1.2-0.4-1.9-1.0-1.01.0-1.0-1.1-1.0-1.0-1.1-1.6
Condit. Reinf. active responses4.35.35.8-2.4-2.4-1.9-1.9-2.4-2.42.4-2.4-2.3-2.4-2.4-2.4-2.2
Condit. Reinf. inactive responses1.01.22.0-1.3-1.0-1.4-0.1-1.2-1.21.2-1.2-1.2-1.2-1.2-1.1-0.6
Incentive salience index mean1.92.33.0-1.5-1.7-1.2-1.5-1.6-1.51.5-1.5-1.5-1.5-1.5-1.5-1.6
Condit. Reinf. lever presses0.00.00.30.0-0.3-0.30.50.00.1-0.10.10.10.00.10.20.3
Time in familiar zone, hab. session 10.10.10.40.20.60.40.40.10.2-0.20.10.00.10.20.00.3
Time in novel zone, hab. session 10.00.00.0-0.2-0.2-0.10.10.0-0.10.10.00.10.0-0.10.20.0
Total zone transitions, hab. session 10.10.21.00.40.41.00.50.30.4-0.40.30.20.30.40.40.4
Total locomotion distance, hab. session 10.40.61.1-0.6-0.80.2-0.7-0.9-0.70.7-0.9-1.1-0.9-0.7-0.8-0.8
Locomotion velocity, hab. session 10.50.71.2-0.6-1.00.1-0.8-1.0-0.80.8-0.9-1.1-1.0-0.8-0.9-0.9
Time in familiar zone, hab. session 20.40.40.80.60.50.10.90.60.6-0.60.60.80.50.60.70.8
Time in novel zone, hab. session 20.10.10.5-0.0-0.00.7-0.40.10.0-0.00.0-0.10.10.0-0.0-0.2
Total zone transitions, hab. session 20.30.41.1-0.5-1.00.5-0.7-0.7-0.50.5-0.6-0.6-0.6-0.5-0.4-0.7
Total locomotion distance, hab. session 21.62.13.7-1.3-1.9-0.4-1.3-1.6-1.41.4-1.6-1.6-1.6-1.4-1.2-1.5
Locomotion velocity, hab. session 22.12.84.6-1.5-2.1-0.5-1.6-1.8-1.61.6-1.8-1.9-1.8-1.6-1.5-1.8
Novel to familiar place preference ratio2.02.12.8-1.5-0.9-0.6-1.7-1.5-1.51.5-1.5-1.6-1.5-1.5-1.6-1.6
Novelty place preference2.12.13.2-1.5-1.0-0.5-1.8-1.5-1.51.5-1.5-1.5-1.5-1.5-1.6-1.7
Time in novel zone, NPP test1.71.82.5-1.4-0.9-0.4-1.6-1.4-1.41.4-1.4-1.5-1.4-1.4-1.5-1.5
Total zone transitions, NPP test0.10.10.80.0-0.90.4-0.3-0.1-0.00.0-0.0-0.1-0.0-0.00.2-0.2
Total locomotion distance, NPP test0.50.62.1-0.6-1.5-0.2-0.6-0.9-0.70.7-0.8-0.9-0.9-0.7-0.6-0.7
Locomotion velocity, NPP test0.60.92.3-0.8-1.5-0.4-0.8-1.1-0.90.9-1.0-1.0-1.0-0.9-0.8-0.9
Pavlov. Cond. lever latency0.30.40.80.70.00.90.10.60.7-0.70.70.80.60.70.70.4
Pavlov. Cond. magazine entry latency0.81.01.4-1.0-0.5-1.1-0.6-0.9-1.11.1-1.0-1.2-0.9-1.1-1.1-0.9
Pavlov. Cond. change in total contacts0.10.10.50.30.70.10.60.10.1-0.10.1-0.10.10.1-0.10.4
Pavlov. Cond. index score1.72.22.9-1.5-1.1-1.4-1.0-1.5-1.61.6-1.6-1.7-1.5-1.6-1.6-1.4
Pavlov. Cond. latency score1.31.62.2-1.3-0.8-1.5-0.7-1.3-1.41.4-1.3-1.5-1.3-1.4-1.4-1.1
Pavlov. Cond. lever contacts0.30.30.5-0.6-0.3-0.7-0.1-0.6-0.70.7-0.6-0.7-0.6-0.7-0.6-0.4
Pavlov. Cond. magazine entry number0.60.71.30.80.10.90.30.80.9-0.90.91.00.80.91.20.7
Pavlov. Cond. intertrial magazine entries0.60.71.0-0.9-1.0-0.8-0.6-0.9-0.80.8-0.9-0.6-0.9-0.8-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.1.62.02.7-1.5-1.1-1.2-1.1-1.4-1.51.5-1.5-1.7-1.4-1.5-1.6-1.4
Pavlov. Cond. response bias0.50.61.0-0.8-0.2-0.8-0.3-0.8-0.80.8-0.8-1.0-0.8-0.8-1.0-0.6
Bone: apparent density0.30.51.3-0.8-1.0-0.4-1.1-0.6-0.70.7-0.6-0.5-0.6-0.7-0.5-0.9
Bone surface0.61.11.9-1.1-1.3-1.3-1.4-1.0-0.90.9-0.9-0.8-0.9-0.9-1.0-1.2
Bone volume0.50.91.4-1.0-1.1-1.2-1.1-0.8-0.90.9-0.8-0.7-0.8-0.9-0.8-1.0
Bone: connectivity density0.10.20.8-0.5-0.9-0.5-0.7-0.2-0.40.4-0.3-0.2-0.2-0.4-0.1-0.5
Bone: cortical apparent density3.64.75.92.12.41.42.42.32.0-2.02.21.92.32.02.32.4
Bone: cortical area8.212.528.1-2.7-3.31.5-5.3-3.6-3.03.0-3.5-3.2-3.6-3.0-4.0-4.6
Bone: cortical porosity0.20.20.9-0.20.6-0.3-0.2-0.4-0.20.2-0.4-0.3-0.4-0.2-0.9-0.3
Bone: cortical porosity0.40.51.5-0.50.1-0.6-0.5-0.7-0.60.6-0.7-0.7-0.8-0.6-1.2-0.6
Bone: cortical thickness6.210.222.0-2.3-2.32.6-4.7-3.2-2.72.7-3.2-3.0-3.2-2.7-3.6-4.2
Bone: cortical thickness2.02.43.9-1.0-0.71.9-2.0-1.6-1.31.3-1.6-1.6-1.6-1.3-1.7-1.9
Bone: cortical tissue density4.25.57.32.22.61.32.72.52.2-2.22.42.12.52.22.52.6
Bone: elastic displacement1.31.52.0-1.3-0.9-0.5-1.3-1.2-1.31.3-1.3-1.4-1.2-1.3-1.3-1.4
Bone: elastic work6.58.512.7-2.8-2.0-0.7-3.6-3.0-2.92.9-3.1-3.0-3.0-2.9-3.3-3.5
Bone: endosteal estimation0.20.31.4-0.2-1.2-0.8-1.0-0.5-0.00.0-0.4-0.1-0.4-0.0-0.6-0.6
Bone: endosteal perimeter1.02.15.0-1.2-1.8-1.5-2.2-1.3-1.11.1-1.3-1.1-1.3-1.1-1.5-1.8
Bone: final force6.510.622.9-2.5-2.91.2-4.8-3.4-2.82.8-3.3-3.0-3.4-2.8-3.8-4.2
Bone: final moment7.312.125.6-2.8-3.10.9-5.1-3.6-3.13.1-3.6-3.2-3.7-3.1-4.0-4.5
Bone: marrow area0.10.31.3-0.1-1.2-0.7-0.9-0.50.0-0.0-0.3-0.1-0.40.0-0.6-0.6
Bone: maximum diameter2.24.011.1-1.5-2.20.6-3.3-2.0-1.51.5-1.9-1.6-1.9-1.5-2.3-2.7
Bone: maximum force7.412.927.2-2.8-3.30.9-5.2-3.8-3.13.1-3.7-3.3-3.8-3.1-4.2-4.6
Bone: maximum moment8.414.629.8-3.1-3.50.6-5.5-4.0-3.33.3-3.9-3.6-4.0-3.3-4.4-4.9
Bone: minimum diameter3.66.713.7-2.2-2.7-0.5-3.7-2.6-2.32.3-2.6-2.5-2.6-2.3-2.8-3.3
Bone: periosteal estimation3.26.516.2-1.9-2.90.3-4.0-2.6-2.02.0-2.5-2.1-2.6-2.0-2.9-3.4
Bone: periosteal perimeter3.55.814.6-1.9-2.2-0.1-3.8-2.4-2.02.0-2.4-2.0-2.4-2.0-2.9-3.2
Bone: post-yield work0.10.21.10.0-0.70.6-1.0-0.2-0.00.0-0.2-0.1-0.2-0.0-0.2-0.6
Bone: stiffness1.62.55.9-0.7-1.22.1-2.4-1.6-1.01.0-1.5-1.4-1.7-1.0-1.9-2.0
Bone: tissue strength2.42.35.6-1.2-1.90.4-2.4-1.5-1.21.2-1.5-1.3-1.5-1.2-1.6-2.0
Bone: trabecular number0.10.10.3-0.5-0.4-0.6-0.2-0.2-0.40.4-0.2-0.1-0.2-0.4-0.1-0.2
Bone: trabecular spacing0.20.21.3-0.3-1.10.2-0.7-0.5-0.30.3-0.4-0.3-0.4-0.3-0.4-0.5
Bone: trabecular thickness0.10.20.4-0.40.3-0.6-0.4-0.3-0.40.4-0.4-0.5-0.4-0.4-0.5-0.4
Bone: trabecular tissue density0.91.31.71.31.30.60.91.11.2-1.21.21.31.11.21.01.2
Breakpoint value in progressive ratio session0.70.81.50.91.10.50.80.90.9-0.90.91.20.80.90.40.9
Distance traveled before self-admin0.20.20.4-0.70.2-0.5-0.6-0.2-0.60.6-0.2-0.3-0.2-0.6-0.7-0.4
Distance traveled after self-admin0.40.41.8-0.8-0.7-1.40.6-0.1-0.70.7-0.4-0.0-0.4-0.7-0.30.2
Delta time in closed arm before/after self-admin0.10.10.40.4-0.10.20.1-0.10.5-0.5-0.1-0.3-0.00.50.60.0
Delta time in open arm before/after self-admin0.50.50.90.60.8-0.40.81.00.5-0.50.80.90.80.50.40.8
Diff in mean of infusions in LGA sessions1.51.72.41.21.30.61.11.41.3-1.31.41.51.41.31.21.5
Extinction: sum of active levers before priming2.12.14.51.42.11.41.31.41.3-1.31.51.81.41.31.21.5
Active lever presses in extinction session 64.74.57.62.12.82.11.52.32.0-2.02.32.52.22.01.52.1
Delta distance traveled before/after self-admin0.60.62.10.40.2-0.31.40.90.5-0.50.70.90.70.51.01.2
Delta ambulatory time before/after self-admin1.41.53.30.80.6-0.21.81.40.9-0.91.31.51.20.91.41.7
Time in closed arm before self-admin0.20.20.80.00.90.30.20.70.0-0.00.70.80.60.0-0.00.6
Time in closed arm after self-admin1.51.53.21.11.80.61.31.21.2-1.21.31.21.31.21.21.4
Time in open arm before self-admin0.60.71.4-0.5-1.20.4-1.1-1.1-0.30.3-0.9-1.0-0.9-0.3-0.3-1.1
Time in open arm after self-admin0.10.10.20.3-0.10.3-0.40.10.4-0.40.10.30.10.40.1-0.1
Sum of active levers in priming session hrs 5-60.20.21.00.30.8-0.61.00.10.0-0.00.10.40.10.0-0.10.6
Time to tail flick, vehicle, before self-admin0.40.40.8-0.9-0.6-0.2-0.2-0.4-0.90.9-0.6-0.8-0.6-0.9-0.6-0.5
Time to tail flick, vehicle, after self-admin1.01.03.01.10.91.70.50.91.1-1.10.90.70.91.10.80.7
Time to tail flick, test, before self-admin0.70.71.90.20.9-0.11.41.20.3-0.31.01.01.00.30.51.4
Time to tail flick, test, after self-admin2.12.13.41.21.41.31.61.91.0-1.01.71.51.71.01.51.7
Delta time to tail flick, vehicle, before/after SA0.20.20.40.40.30.10.50.20.6-0.60.30.10.30.60.40.5
Delta time to tail flick, test, before/after SA0.80.72.41.01.01.60.30.60.8-0.80.70.70.70.80.80.5
Ambulatory time before self-admin0.70.71.0-1.0-0.1-0.5-1.0-0.6-1.01.0-0.7-0.8-0.7-1.0-1.0-0.9
Ambulatory time after self-admin0.10.10.3-0.3-0.1-0.50.50.3-0.30.30.10.50.1-0.30.00.4
Total heroin consumption0.80.94.10.91.42.0-0.30.80.6-0.61.01.10.80.6-0.10.4
Area under the delay curve2.12.23.31.41.41.71.31.81.2-1.21.51.71.61.21.71.4
Delay disc. indifference point, 0s delay0.20.21.60.5-0.21.3-0.6-0.00.3-0.30.10.1-0.10.30.1-0.5
Delay disc. indifference point, 16s delay1.41.42.51.20.71.11.41.50.9-0.91.11.41.20.91.61.2
Delay disc. indifference point, 2s delay0.60.61.00.90.71.00.50.80.9-0.90.80.90.80.90.60.7
Delay disc. indifference point, 24s delay5.25.07.42.02.41.82.02.62.0-2.02.42.72.52.02.32.3
Delay disc. indifference point, 4s delay0.80.92.00.80.91.40.21.30.6-0.61.10.81.20.61.10.5
Delay disc. indifference point, 8s delay1.51.53.01.11.21.70.91.31.1-1.11.31.41.31.11.41.1
Delay discount exponential model param3.13.34.9-1.6-1.8-1.9-1.6-2.2-1.41.4-1.9-2.0-2.0-1.4-1.9-1.8
Delay discount hyperbolic model param2.93.14.6-1.6-1.8-1.8-1.5-2.1-1.41.4-1.8-2.0-2.0-1.4-1.9-1.7
Fecal boli incidents, locomotor time 10.10.10.20.30.1-0.30.40.20.3-0.30.10.40.20.3-0.00.4
Change in fecal boli incidents, locomotor task4.24.06.21.72.40.82.52.11.9-1.92.01.92.01.92.02.3
Time >=10cm from walls, locomotor time 10.80.82.0-1.0-1.4-1.1-0.9-0.3-1.21.2-0.3-0.7-0.4-1.2-0.2-0.8
Bouts of movement, locomotor time 10.50.61.00.81.00.20.80.80.7-0.70.80.70.70.70.70.8
Total resting periods, locomotor time 10.80.91.60.91.30.21.11.00.8-0.81.00.90.90.80.91.0
Rest time, locomotor task time 10.10.10.20.30.4-0.50.50.10.3-0.3-0.00.2-0.00.3-0.10.3
Distance moved, locomotor task time 10.40.40.90.30.30.80.50.90.4-0.40.90.50.80.41.00.6
Vertical activity count, locomotor time 10.10.10.3-0.1-0.50.1-0.60.1-0.10.10.1-0.4-0.1-0.1-0.1-0.4
Time >=10cm from walls, locomotor time 21.11.22.8-0.9-1.20.4-1.7-1.2-0.80.8-1.0-1.3-1.0-0.8-1.0-1.5
Bouts of movement, locomotor time 21.11.22.51.21.01.60.81.01.1-1.11.01.11.01.11.30.9
Total resting periods, locomotor time 20.50.51.50.90.51.20.30.60.7-0.70.70.60.60.70.90.5
Rest time, locomotor task time 20.10.11.1-0.3-0.2-1.0-0.0-0.1-0.30.30.20.0-0.1-0.3-0.10.1
Distance moved, locomotor task time 20.20.32.60.30.51.60.30.40.2-0.20.10.10.20.20.50.1
Vertical activity count, locomotor time 20.30.31.80.2-0.41.3-0.6-0.20.0-0.0-0.5-0.4-0.40.0-0.4-0.7
Weight adjusted by age3.13.56.2-1.5-1.8-0.4-2.1-2.4-1.31.3-2.2-2.1-2.1-1.3-2.1-2.5
Seeking ratio, delayed vs. immediate footshock1.31.52.2-1.5-1.1-1.1-1.2-1.0-1.51.5-0.8-1.4-1.0-1.5-1.1-1.2
Locomotion in novel chamber0.20.30.70.6-0.50.8-0.5-0.20.8-0.8-0.1-0.0-0.10.80.3-0.4
Locomotion in novel chamber post-restriction2.83.34.5-1.9-2.0-1.8-1.5-2.1-1.71.7-1.7-2.0-1.9-1.7-1.9-1.7
Progressive ratio0.30.41.10.50.60.20.20.80.6-0.61.00.90.70.60.30.5
Food seeking constrained by brief footshock0.20.30.50.30.7-0.40.60.60.4-0.40.50.40.60.40.50.7
Seeking ratio, punishment vs. effort0.20.20.5-0.4-0.6-0.4-0.2-0.5-0.40.4-0.7-0.7-0.4-0.4-0.1-0.4
Run reversals in cocaine runway, females0.10.10.40.2-0.1-0.60.00.30.3-0.30.40.30.20.30.10.1
Run reversals in cocaine runway, males0.30.31.1-0.6-0.0-0.8-0.2-0.7-0.40.4-0.6-0.6-0.6-0.4-1.1-0.4
Latency to leave start box in cocaine runway0.10.10.2-0.20.1-0.00.30.3-0.20.20.50.00.2-0.2-0.20.5
Latency to leave start box in cocaine runway, F0.20.20.4-0.6-0.40.3-0.3-0.1-0.60.60.1-0.4-0.2-0.6-0.60.0
Latency to leave start box in cocaine runway, M0.10.10.50.10.1-0.60.70.00.1-0.10.10.10.00.10.10.4
Cd content in liver2.02.23.41.41.41.81.31.41.5-1.51.51.61.41.51.41.4
Co content in liver0.30.30.40.60.20.00.40.60.7-0.70.60.60.60.70.60.5
Cu content in liver0.00.00.20.10.40.00.20.1-0.10.1-0.00.0-0.0-0.1-0.00.1
Fe content in liver1.51.83.01.40.90.51.01.41.5-1.51.51.71.51.51.21.3
K content in liver1.31.33.0-1.4-1.4-1.7-0.4-0.9-1.31.3-1.0-1.0-1.0-1.3-0.8-0.7
Mg content in liver0.20.21.0-0.5-0.5-1.00.80.1-0.30.3-0.0-0.1-0.0-0.30.30.4
Mn content in liver0.10.10.4-0.4-0.10.00.1-0.3-0.50.5-0.4-0.6-0.4-0.5-0.4-0.2
Na content in liver0.20.20.30.30.4-0.30.50.60.4-0.40.50.40.60.40.60.5
Rb content in liver1.31.62.0-1.3-1.4-0.5-1.2-1.2-1.41.4-1.3-1.1-1.3-1.4-1.3-1.3
Se content in liver0.30.42.8-0.6-0.3-1.70.5-0.1-0.60.6-0.2-0.4-0.1-0.60.00.1
Sr content in liver0.10.10.50.10.7-0.10.30.40.1-0.10.30.10.30.10.20.3
Zn content in liver0.10.10.30.2-0.00.10.10.30.3-0.30.30.50.20.30.20.2