Hub : Genes

Asap3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000049714 0.27 0.1 0.0e+00 0.24 0.24 0.23 0.23 2.3e-26 1.7e-26 1.1e-24 1.9e-25
2 BLA gene expression ENSRNOG00000049714 0.13 0.09 4.8e-04 0.04 0.04 0.02 0.04 3.2e-03 3.2e-03 2.9e-02 4.0e-03
3 Brain gene expression ENSRNOG00000049714 0.32 0.1 0.0e+00 0.41 0.42 0.42 0.42 8.6e-41 1.6e-41 4.4e-42 3.5e-42
4 LHb gene expression ENSRNOG00000049714 0.4 0.14 2.5e-10 0.41 0.43 0.42 0.42 8.2e-11 1.7e-11 4.4e-11 4.0e-11
5 Liver gene expression ENSRNOG00000049714 0.03 0.03 4.0e-04 0.02 0.02 0.02 0.02 3.0e-03 1.9e-03 3.8e-03 3.9e-03
6 NAcc gene expression ENSRNOG00000049714 0.06 0.04 5.0e-06 0.06 0.05 0.05 0.05 2.5e-05 9.9e-05 1.3e-04 7.2e-05
7 PL gene expression ENSRNOG00000049714 0.06 0.04 3.6e-05 0.06 0.06 0.06 0.06 3.0e-05 3.7e-05 1.5e-05 1.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail2.37.510.9-3.3-1.4-2.8-3.03.1-3.0-2.0
BMI without tail2.14.35.8-2.4-1.5-2.1-2.22.4-2.2-1.7
Body weight4.820.428.8-5.0-3.1-4.5-4.74.6-5.4-3.8
Epididymis fat weight0.51.22.1-1.4-0.3-0.8-1.21.4-1.5-0.6
Glucose0.10.20.5-0.50.7-0.4-0.3-0.0-0.30.3
Heart weight0.10.10.3-0.40.1-0.4-0.3-0.2-0.6-0.1
Left kidney weight5.214.919.6-4.2-3.1-3.9-4.13.7-4.4-3.5
Right kidney weight1.23.45.7-2.0-1.4-1.8-1.91.5-2.4-1.7
Tail length0.51.52.9-1.2-1.1-1.2-1.11.0-1.7-1.2
Length with tail1.34.79.1-2.3-1.6-2.1-2.21.8-3.0-1.9
Length without tail1.84.06.5-2.2-1.3-2.1-2.11.7-2.6-1.8
Liver weight, left3.96.38.7-2.8-1.9-2.4-2.62.5-3.0-2.2
Liver weight, right2.54.15.1-2.2-1.9-1.9-2.11.6-2.3-2.0
Parametrial fat weight0.30.61.70.31.30.70.5-0.30.41.2
Retroperitoneal fat weight0.10.30.9-0.40.90.1-0.10.1-0.60.6
Intraocular pressure0.60.82.3-0.4-1.5-0.6-0.60.7-0.7-1.2
Extensor digitorum longus weight0.83.13.6-1.5-1.9-1.8-1.71.5-1.9-1.9
Soleus weight4.212.213.2-3.3-3.5-3.5-3.43.5-3.6-3.6
Tibialis anterior weight2.48.49.0-2.8-2.9-3.0-3.02.8-3.0-3.0
Tibia length1.54.15.4-2.0-1.9-1.7-2.12.3-2.1-2.1
Number of licking bursts0.20.30.50.50.40.50.5-0.70.50.5
Food consumed during 24 hour testing period0.10.10.20.4-0.00.20.3-0.30.30.1
Times rat made contact with spout1.92.23.82.00.61.61.6-1.51.71.0
Mean time between licks in bursts0.30.40.6-0.8-0.3-0.6-0.60.7-0.7-0.5
Mean num. licks in bursts0.20.30.60.80.10.60.6-0.40.70.3
Std. dev. time between licks in bursts0.70.81.2-0.9-1.1-0.7-0.80.9-0.7-1.0
Water consumed over 24 hours1.82.13.71.90.71.21.6-1.71.61.0
Indifference point 0 sec0.40.72.60.0-1.6-0.6-0.40.2-0.2-1.2
Indifference point AUC1.51.73.4-1.0-1.8-1.1-1.21.2-1.0-1.7
Indifference point function ln k1.21.82.11.31.41.31.4-1.01.31.5
Indifference point function log k1.21.82.11.31.41.31.4-1.01.31.5
Delay discounting total patch changes 0 sec0.40.62.40.1-1.6-0.5-0.30.1-0.2-1.2
Delay discounting total patch changes 12 sec1.01.43.9-0.5-2.0-0.8-0.90.7-0.8-1.7
Delay discounting total patch changes 18 sec1.01.34.8-0.1-2.2-0.7-0.60.4-0.7-1.7
Delay discounting total patch changes 24 sec1.31.74.2-0.6-2.0-1.0-1.00.7-1.2-1.8
Delay discounting total patch changes 6 sec1.11.75.6-0.4-2.4-0.9-0.90.5-0.6-1.9
Delay discounting time to switch 0 sec0.61.01.40.91.01.00.9-1.20.91.0
Delay discounting water rate 0 sec0.10.20.60.7-0.10.50.6-0.40.40.2
Delay discounting water rate 12 sec0.10.10.3-0.2-0.6-0.3-0.20.3-0.5-0.5
Delay discounting water rate 18 sec1.31.72.3-1.1-1.4-1.5-1.21.4-1.3-1.4
Delay discounting water rate 24 sec0.40.61.01.00.60.60.9-0.60.80.7
Delay discounting water rate 6 sec0.40.60.80.80.70.80.9-0.70.60.7
Locomotor activity7.812.414.1-3.8-3.1-3.6-3.73.2-3.7-3.5
Locomotor testing distance3.96.57.2-2.7-2.3-2.6-2.72.5-2.5-2.6
Locomotor testing rearing4.26.67.3-2.6-2.6-2.6-2.62.6-2.3-2.7
Light reinforcement 10.51.01.5-0.8-1.2-1.0-0.90.5-1.2-1.2
Light reinforcement 20.40.50.7-0.6-0.8-0.7-0.60.7-0.7-0.8
Reaction time number correct0.40.61.20.71.10.60.8-0.50.71.0
Reaction time mean minus median0.20.20.3-0.4-0.5-0.6-0.50.6-0.4-0.5
Reaction time mean minus median AUC0.10.10.3-0.1-0.5-0.3-0.30.3-0.1-0.4
Reaction time num false alarms0.60.91.1-0.9-1.0-0.9-0.91.1-0.8-1.0
Reaction time num false alarms AUC0.81.11.6-1.1-0.8-1.1-1.01.3-1.0-1.0
Reaction time trials correct on left0.40.61.20.71.10.60.8-0.50.71.0
Reaction time trials on left0.50.71.20.71.10.60.8-0.50.71.1
Reaction time mean0.10.20.50.3-0.7-0.10.1-0.40.0-0.5
Reaction time mean AUC0.10.20.40.6-0.30.30.4-0.60.4-0.1
Median of all reaction times0.20.20.60.6-0.40.20.4-0.80.3-0.3
Reaction time omissions0.10.20.8-0.1-0.3-0.2-0.30.9-0.5-0.2
Reaction time false alarm rate1.11.61.9-1.3-1.2-1.2-1.31.4-1.2-1.3
Reaction time premature initiation rate1.82.43.61.90.81.71.7-1.71.71.1
Reaction time premature initiations2.13.04.32.11.21.81.9-1.61.81.5
Std. dev. reaction times0.10.10.30.1-0.6-0.2-0.10.3-0.2-0.4
Reaction time trials completed0.50.71.20.71.10.60.8-0.50.71.1
Reaction time trials AUC0.30.50.90.61.00.40.7-0.40.60.9
Social response proportion0.60.71.60.71.30.40.6-1.10.11.0
Social responses2.73.44.7-2.0-1.3-2.1-2.01.8-2.2-1.6
Social time0.10.20.5-0.40.2-0.5-0.40.3-0.7-0.1
Conditioned locomotion2.02.33.21.81.11.81.7-1.21.51.4
Cocaine response after cond. corrected4.65.26.42.22.52.02.3-2.02.22.5
Cocaine response after cond. not corrected4.75.25.92.42.12.12.4-2.22.42.3
Cocaine response before conditioning0.70.92.2-0.6-1.5-0.8-0.80.7-0.8-1.3
Saline control response0.60.82.11.1-0.20.70.9-1.51.00.1
Condit. Reinf. active minus inactive responses1.72.12.8-1.6-1.1-1.5-1.41.5-1.7-1.2
Condit. Reinf. active-inactive response ratio0.40.41.40.01.20.50.3-0.30.01.0
Condit. Reinf. active responses5.98.29.2-2.7-3.0-2.9-2.82.6-3.0-3.0
Condit. Reinf. inactive responses9.111.316.6-2.8-4.1-3.3-3.13.0-3.1-3.9
Condit. Reinf. lever presses2.33.15.8-1.2-2.4-1.6-1.51.4-1.8-2.2
Condit. Reinf. lever reinforcers received5.37.58.8-2.5-3.0-2.8-2.62.4-2.8-3.0
Pavlov. Cond. lever latency1.21.64.40.52.10.80.8-0.91.21.7
Pavlov. Cond. magazine entry latency0.00.00.10.3-0.10.10.10.1-0.3-0.1
Pavlov. Cond. change in total contacts2.12.93.9-1.4-2.0-1.5-1.51.5-1.9-1.9
Pavlov. Cond. index score0.50.61.9-0.1-1.4-0.4-0.40.5-0.8-1.1
Pavlov. Cond. latency score0.30.41.30.0-1.1-0.2-0.20.3-0.6-0.9
Pavlov. Cond. lever contacts1.62.25.0-0.8-2.2-1.1-1.11.2-1.6-1.9
Pavlov. Cond. magazine entry number0.50.61.10.41.00.60.6-0.61.10.9
Pavlov. Cond. intertrial magazine entries1.11.41.71.01.31.21.2-1.31.11.3
Pavlov. Cond. lever-magazine prob. diff.0.50.72.2-0.2-1.5-0.4-0.50.5-0.8-1.2
Pavlov. Cond. response bias1.31.83.6-0.8-1.9-1.1-1.11.0-1.5-1.7
Conditioned reinforcement - actives1.81.73.0-1.6-0.8-1.3-1.41.7-1.1-1.1
Conditioned reinforcement - inactives1.51.72.1-1.5-1.2-1.3-1.41.3-1.2-1.3
Conditioned locomotion2.22.74.3-1.9-1.0-1.6-1.82.1-1.6-1.3
Intermittent access intake day 1-15 change4.64.56.6-2.2-1.9-2.0-2.22.6-2.1-2.0
Intermittent access intake escalation3.02.94.8-1.7-1.4-1.6-1.72.2-1.7-1.5
Intermittent access intake escalation 20.90.92.3-0.9-0.8-0.7-0.91.5-0.8-0.9
Intermitt. access day 1 inactive lever presses4.75.15.6-2.2-2.2-2.2-2.32.2-2.3-2.4
Intermitt. access day 15 inactive lever presses1.71.92.4-1.4-1.4-1.4-1.41.6-1.0-1.4
Intermitt. access escalation Index1.41.32.1-0.8-1.5-1.2-1.00.7-1.2-1.4
Intermittent access day 1 total infusions1.11.22.0-1.4-1.2-0.8-1.21.3-0.7-1.0
Intermittent access day 15 total infusions4.45.06.8-2.4-2.3-1.9-2.32.6-1.9-2.1
Intermittent access terminal intake (last 3 days)2.93.24.6-1.9-2.1-1.3-1.82.1-1.3-1.8
Intermittent access total infusions2.12.43.8-1.8-1.6-1.1-1.61.9-1.0-1.4
Intermittent access day 1 locomotion0.40.40.8-0.9-0.6-0.3-0.70.8-0.4-0.4
Intermittent access day 15 total locomotion0.20.20.9-0.20.00.5-0.10.90.20.2
Intermittent access total locomotion0.70.71.5-1.0-0.9-0.5-0.91.2-0.7-0.8
Intermittent access standard deviation7.47.910.2-3.2-2.2-2.7-3.03.1-2.8-2.5
Cocaine induced anxiety0.20.20.70.40.60.00.3-0.80.10.4
Post-drug Anxiety1.01.12.51.30.90.71.1-1.60.70.9
Baseline Anxiety0.00.00.10.1-0.2-0.00.10.1-0.1-0.1
Lifetime Intake1.41.52.6-1.6-1.3-0.9-1.31.6-0.6-1.1
Incentive Sensitization - Responses0.80.81.8-0.7-1.3-0.6-0.80.7-0.5-1.1
Incentive Sensitization - Breakpoint0.80.81.6-0.8-1.3-0.6-0.90.8-0.6-1.1
Progressive ratio test 1 active lever presses0.60.61.5-0.9-0.7-0.4-0.81.2-0.3-0.5
Progressive ratio test 1 breakpoint0.70.71.9-1.0-0.9-0.4-0.91.4-0.4-0.7
Progressive ratio test 1 inactive lever presses1.21.22.4-1.4-0.8-0.9-1.21.5-0.9-0.8
Progressive ratio test 2 active lever presses0.90.91.5-1.0-1.2-0.6-1.01.2-0.5-1.0
Progressive ratio test 2 breakpoint0.91.01.5-1.1-1.2-0.7-1.01.2-0.5-1.0
Progressive ratio test 2 inactive lever presses1.51.73.6-1.5-1.2-0.9-1.41.9-0.9-1.1
Total sessions with >9 infusions2.52.74.4-2.1-1.3-1.6-1.91.9-1.3-1.4
Short access day 1 total inactive lever presses0.80.91.4-1.2-1.1-0.5-1.01.2-0.6-0.9
Short access day 10 total inactive lever presses3.23.54.6-1.6-2.2-1.8-1.81.6-1.8-2.2
Short access day 1 total infusions2.12.23.2-1.8-1.6-1.3-1.61.6-0.9-1.5
Short access day 10 total infusions0.60.71.2-1.1-0.8-0.6-0.91.0-0.4-0.7
Short access total infusions0.60.71.6-1.3-0.7-0.6-0.91.1-0.2-0.6
Short access day 1 locomotion0.70.71.4-1.1-0.6-0.7-1.01.2-0.6-0.6
Short access day 10 total locomotion4.14.55.7-2.4-1.5-2.2-2.32.4-2.1-1.9
Short access total locomotion2.82.85.1-2.2-0.8-1.5-1.92.3-1.4-1.1
Compulsive drug intake1.51.52.1-1.3-0.9-1.4-1.30.6-1.5-1.2
One hour access (0.3 mA shock)3.54.04.8-2.0-2.2-1.9-2.02.1-1.7-2.1
One hour access (shock baseline)1.41.62.7-1.2-1.6-1.0-1.21.6-0.9-1.3
Number of responses in last shaping day0.30.31.1-0.8-0.3-0.3-0.61.0-0.4-0.2
Context. condit. distance diff. score1.51.83.1-1.1-1.7-1.2-1.21.1-1.4-1.7
Locomotion velocity, session 11.01.12.1-0.7-1.5-0.9-0.90.9-0.8-1.3
Locomotion distance, session 10.10.20.70.2-0.80.0-0.10.4-0.1-0.5
Locomotion velocity, session 22.42.83.31.71.71.71.7-1.41.81.7
Locomotion distance, session 20.71.02.0-0.7-1.4-1.0-0.91.0-0.6-1.3
Locomotion velocity, session 30.50.61.21.1-0.20.90.9-1.10.70.2
Locomotion distance, session 31.61.74.3-0.7-2.1-1.0-1.11.1-1.0-1.7
Stereotopy head waving bouts, day 31.01.11.40.91.21.11.1-1.20.91.1
Stereotopy head waving duration, day 31.72.13.01.21.71.31.4-1.51.21.6
Locomotion velocity, session 71.92.14.5-1.1-2.1-1.1-1.31.2-1.1-1.9
Locomotion distance, session 70.30.41.2-0.3-1.1-0.5-0.50.4-0.3-0.9
Stereotopy head waving bouts, day 70.10.10.3-0.20.30.1-0.10.2-0.50.1
Stereotopy head waving duration, day 70.10.20.7-0.40.2-0.3-0.40.4-0.8-0.1
Locomotion velocity, session 80.30.30.7-0.6-0.5-0.5-0.50.6-0.8-0.5
Locomotion distance, session 82.53.75.8-1.6-2.4-1.7-1.81.7-1.9-2.3
Degree of sensitization distance1.81.83.31.01.81.11.2-1.31.21.6
Degree of sensitization stereotypy0.80.91.8-1.1-0.3-0.7-1.01.2-1.3-0.6
Condit. Reinf. active minus inactive responses0.91.02.10.91.50.90.8-0.70.41.2
Condit. Reinf. active-inactive response ratio0.80.92.50.71.60.80.7-0.50.31.3
Condit. Reinf. active responses0.30.30.50.70.60.70.5-0.30.50.6
Condit. Reinf. inactive responses0.20.21.0-0.0-1.0-0.1-0.20.30.2-0.7
Incentive salience index mean0.40.50.70.90.70.80.7-0.60.50.7
Condit. Reinf. lever presses0.10.10.50.3-0.70.20.10.00.4-0.4
Time in familiar zone, hab. session 10.20.20.50.7-0.20.40.5-0.60.40.0
Time in novel zone, hab. session 10.00.00.1-0.20.3-0.0-0.00.10.00.2
Total zone transitions, hab. session 10.20.20.8-0.1-0.9-0.2-0.40.2-0.3-0.7
Total locomotion distance, hab. session 10.10.20.7-0.1-0.9-0.2-0.30.2-0.2-0.6
Locomotion velocity, hab. session 10.10.10.40.2-0.60.1-0.0-0.10.0-0.4
Time in familiar zone, hab. session 20.80.81.91.4-0.40.81.0-1.21.00.0
Time in novel zone, hab. session 20.10.10.50.10.70.20.3-0.30.10.6
Total zone transitions, hab. session 21.11.43.4-0.6-1.8-0.8-1.01.3-0.5-1.6
Total locomotion distance, hab. session 20.30.41.50.1-1.2-0.0-0.20.40.3-0.9
Locomotion velocity, hab. session 20.60.82.4-0.4-1.6-0.5-0.70.8-0.2-1.3
Novel to familiar place preference ratio0.20.20.8-0.30.90.1-0.10.1-0.20.6
Novelty place preference0.20.20.5-0.50.7-0.0-0.20.3-0.40.5
Time in novel zone, NPP test0.10.10.5-0.30.70.1-0.1-0.0-0.20.5
Total zone transitions, NPP test0.30.51.0-0.5-1.0-0.4-0.60.7-0.3-0.9
Total locomotion distance, NPP test0.10.10.60.3-0.80.20.0-0.00.2-0.5
Locomotion velocity, NPP test0.10.20.7-0.0-0.80.0-0.20.3-0.0-0.6
Pavlov. Cond. lever latency0.10.10.3-0.10.60.10.1-0.4-0.40.4
Pavlov. Cond. magazine entry latency0.10.10.50.1-0.7-0.0-0.10.30.0-0.5
Pavlov. Cond. change in total contacts0.10.10.20.3-0.20.20.10.10.4-0.1
Pavlov. Cond. index score0.20.30.6-0.2-0.8-0.4-0.40.6-0.0-0.7
Pavlov. Cond. latency score0.10.20.5-0.0-0.7-0.2-0.20.50.2-0.5
Pavlov. Cond. lever contacts0.10.10.30.3-0.4-0.00.10.10.6-0.2
Pavlov. Cond. magazine entry number1.11.43.10.81.81.01.1-1.10.81.5
Pavlov. Cond. intertrial magazine entries7.89.310.22.93.22.93.0-3.23.03.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.0-0.5-0.2-0.20.40.1-0.4
Pavlov. Cond. response bias0.40.51.5-0.2-1.2-0.4-0.50.6-0.2-1.0
Bone: apparent density1.32.12.9-1.1-1.7-1.5-1.31.3-1.6-1.7
Bone surface1.52.73.6-1.3-1.8-1.7-1.51.6-1.9-1.8
Bone volume1.32.22.8-1.1-1.7-1.5-1.31.4-1.7-1.7
Bone: connectivity density0.50.71.1-0.5-1.1-0.8-0.70.8-0.9-1.0
Bone: cortical apparent density0.20.20.40.60.30.40.5-0.70.30.4
Bone: cortical area3.45.16.7-2.1-2.6-2.1-2.11.8-2.4-2.5
Bone: cortical porosity1.71.92.61.41.11.61.4-1.21.51.3
Bone: cortical porosity2.62.83.31.61.71.81.6-1.41.61.8
Bone: cortical thickness1.52.43.7-1.4-1.9-1.4-1.40.9-1.9-1.8
Bone: cortical thickness0.30.30.90.3-0.90.10.1-0.5-0.8-0.7
Bone: cortical tissue density0.30.40.70.70.50.50.7-0.80.50.6
Bone: elastic displacement0.40.51.21.1-0.10.70.8-0.60.60.3
Bone: elastic work0.20.20.90.4-1.0-0.00.1-0.10.0-0.6
Bone: endosteal estimation2.45.17.3-2.4-1.7-2.2-2.32.7-2.3-2.0
Bone: endosteal perimeter2.24.56.0-2.2-1.8-2.1-2.12.4-2.0-2.0
Bone: final force2.33.86.0-1.7-2.4-1.7-1.81.7-1.9-2.3
Bone: final moment3.05.07.2-2.0-2.7-2.1-2.12.0-2.1-2.6
Bone: marrow area2.45.27.4-2.4-1.7-2.2-2.32.7-2.4-2.0
Bone: maximum diameter3.97.27.9-2.6-2.7-2.6-2.62.5-2.8-2.8
Bone: maximum force3.35.87.7-2.2-2.8-2.2-2.32.2-2.3-2.7
Bone: maximum moment4.27.29.2-2.5-3.0-2.6-2.62.6-2.5-3.0
Bone: minimum diameter1.22.23.4-1.6-1.2-1.3-1.51.4-1.8-1.4
Bone: periosteal estimation4.28.510.1-2.9-2.7-2.8-2.93.0-3.2-2.9
Bone: periosteal perimeter4.26.98.0-2.6-2.8-2.5-2.62.5-2.6-2.8
Bone: post-yield work0.81.12.4-1.2-0.6-0.9-1.11.5-1.1-0.8
Bone: stiffness5.08.08.6-2.9-2.7-2.7-2.82.8-2.9-2.9
Bone: tissue strength2.22.12.7-1.6-1.0-1.6-1.61.6-1.3-1.3
Bone: trabecular number0.60.91.4-0.6-1.2-0.9-0.80.9-0.9-1.1
Bone: trabecular spacing1.21.53.20.81.81.21.0-0.91.01.6
Bone: trabecular thickness0.81.01.7-0.6-1.3-1.0-0.80.7-1.1-1.3
Bone: trabecular tissue density0.30.40.7-0.8-0.1-0.7-0.70.7-0.8-0.3
Breakpoint value in progressive ratio session0.50.61.51.1-0.30.50.8-1.20.40.1
Distance traveled before self-admin4.24.55.4-2.0-2.3-2.2-2.11.7-2.1-2.3
Distance traveled after self-admin3.43.75.1-1.8-2.3-1.8-1.91.8-1.8-2.1
Delta time in closed arm before/after self-admin0.10.10.3-0.00.50.2-0.00.40.10.5
Delta time in open arm before/after self-admin0.10.10.50.30.20.10.3-0.70.10.2
Diff in mean of infusions in LGA sessions0.70.81.51.20.21.11.0-0.81.10.5
Extinction: sum of active levers before priming0.70.71.7-0.6-0.6-1.1-0.70.3-1.3-0.8
Active lever presses in extinction session 60.60.61.00.81.00.70.7-0.60.50.9
Delta distance traveled before/after self-admin0.10.10.30.30.00.50.3-0.10.50.2
Delta ambulatory time before/after self-admin0.30.40.80.40.50.90.5-0.20.80.6
Time in closed arm before self-admin3.03.44.9-1.7-2.2-1.8-1.71.2-1.7-2.2
Time in closed arm after self-admin0.30.30.8-0.7-0.4-0.2-0.60.9-0.3-0.5
Time in open arm before self-admin0.91.01.51.01.21.11.0-0.40.81.2
Time in open arm after self-admin1.51.73.11.11.81.11.2-1.10.91.7
Sum of active levers in priming session hrs 5-60.20.20.7-0.1-0.3-0.6-0.3-0.1-0.8-0.4
Time to tail flick, vehicle, before self-admin0.40.41.1-0.61.0-0.5-0.40.6-0.40.5
Time to tail flick, vehicle, after self-admin0.30.31.4-0.11.20.20.10.00.50.9
Time to tail flick, test, before self-admin0.40.40.6-0.7-0.6-0.8-0.60.3-0.6-0.7
Time to tail flick, test, after self-admin0.40.40.9-0.7-0.1-0.9-0.70.2-1.0-0.4
Delta time to tail flick, vehicle, before/after SA0.00.00.0-0.10.00.1-0.10.00.10.1
Delta time to tail flick, test, before/after SA0.00.00.1-0.10.1-0.2-0.1-0.1-0.20.0
Ambulatory time before self-admin2.93.14.8-1.4-2.2-1.8-1.61.2-1.6-2.1
Ambulatory time after self-admin2.62.94.3-1.5-2.1-1.5-1.61.5-1.6-1.9
Total heroin consumption0.20.20.5-0.1-0.7-0.5-0.30.0-0.6-0.6
Area under the delay curve0.50.61.4-0.80.0-0.6-0.81.0-1.2-0.2
Delay disc. indifference point, 0s delay1.21.32.7-0.9-1.0-1.0-1.11.0-1.6-1.1
Delay disc. indifference point, 16s delay0.30.40.7-0.60.1-0.6-0.60.8-0.8-0.0
Delay disc. indifference point, 2s delay0.70.82.2-0.9-0.3-0.8-1.00.8-1.5-0.6
Delay disc. indifference point, 24s delay0.30.30.90.10.90.30.3-0.00.20.8
Delay disc. indifference point, 4s delay0.50.61.6-0.70.1-0.7-0.80.8-1.3-0.1
Delay disc. indifference point, 8s delay0.60.71.4-0.9-0.2-0.6-0.81.1-1.2-0.4
Delay discount exponential model param0.50.51.30.8-0.20.60.7-1.01.10.1
Delay discount hyperbolic model param0.60.71.70.9-0.10.70.8-1.01.30.2
Fecal boli incidents, locomotor time 12.73.03.6-1.8-1.3-1.9-1.91.5-1.9-1.6
Change in fecal boli incidents, locomotor task3.23.05.01.42.21.71.7-1.31.52.2
Time >=10cm from walls, locomotor time 10.30.30.5-0.5-0.7-0.6-0.50.6-0.5-0.7
Bouts of movement, locomotor time 10.40.51.40.01.20.80.3-0.00.31.0
Total resting periods, locomotor time 10.40.51.5-0.01.20.80.3-0.00.31.0
Rest time, locomotor task time 11.92.14.70.82.21.41.1-1.01.21.9
Distance moved, locomotor task time 11.31.42.2-0.7-1.5-1.2-1.00.8-1.3-1.5
Vertical activity count, locomotor time 12.62.85.4-1.0-2.3-1.6-1.41.0-1.7-2.1
Time >=10cm from walls, locomotor time 20.00.00.2-0.20.0-0.4-0.0-0.20.1-0.1
Bouts of movement, locomotor time 21.61.72.51.21.51.41.3-1.11.11.6
Total resting periods, locomotor time 22.52.63.81.41.91.71.5-1.41.32.0
Rest time, locomotor task time 22.73.14.51.52.11.81.6-1.51.62.1
Distance moved, locomotor task time 21.82.13.2-1.1-1.7-1.5-1.31.3-1.3-1.8
Vertical activity count, locomotor time 23.13.45.9-1.2-2.4-1.8-1.61.2-1.9-2.4
Weight adjusted by age0.20.20.6-0.00.80.20.2-0.20.30.6
Seeking ratio, delayed vs. immediate footshock1.92.22.7-1.4-1.5-1.5-1.51.2-1.6-1.6
Locomotion in novel chamber3.23.94.7-1.9-2.2-2.1-1.91.7-1.8-2.2
Locomotion in novel chamber post-restriction0.81.01.6-1.3-0.8-0.8-1.01.3-0.8-0.8
Progressive ratio0.00.00.1-0.00.00.3-0.10.4-0.20.0
Food seeking constrained by brief footshock0.20.20.30.50.40.50.5-0.50.40.3
Seeking ratio, punishment vs. effort0.00.00.10.10.2-0.10.1-0.40.10.1
Run reversals in cocaine runway, females0.20.20.7-0.1-0.9-0.3-0.30.2-0.3-0.7
Run reversals in cocaine runway, males0.20.20.6-0.6-0.2-0.5-0.50.3-0.8-0.3
Latency to leave start box in cocaine runway1.01.11.90.71.10.90.9-1.41.01.1
Latency to leave start box in cocaine runway, F0.10.10.2-0.40.1-0.3-0.2-0.4-0.3-0.1
Latency to leave start box in cocaine runway, M6.46.27.42.32.42.52.5-2.42.72.5
Cd content in liver2.22.42.8-1.6-1.7-1.4-1.61.7-1.2-1.7
Co content in liver0.20.20.50.4-0.70.30.3-0.20.4-0.4
Cu content in liver1.51.92.61.60.51.61.5-1.51.60.9
Fe content in liver0.20.30.4-0.4-0.6-0.5-0.50.2-0.6-0.6
K content in liver0.00.00.10.10.30.30.2-0.10.10.3
Mg content in liver0.00.00.0-0.0-0.0-0.0-0.00.0-0.2-0.0
Mn content in liver1.71.92.9-1.6-0.7-1.6-1.51.3-1.7-1.0
Na content in liver2.42.53.8-1.4-1.7-1.4-1.51.4-1.9-1.7
Rb content in liver0.00.10.20.10.3-0.00.2-0.5-0.10.3
Se content in liver1.21.53.50.71.91.11.0-1.00.71.6
Sr content in liver2.82.53.7-1.4-1.7-1.5-1.51.9-1.4-1.7
Zn content in liver0.70.72.2-0.5-1.5-0.6-0.70.5-0.4-1.2