Hub : Genes

Tafa5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000049349 0.26 0.11 1.3e-07 0.12 0.09 0.1 0.1 3.4e-07 1.1e-05 7.9e-06 4.2e-06
2 BLA mRNA stability ENSRNOG00000049349 0.36 0.15 1.2e-14 0.16 0.2 0.22 0.22 5.7e-09 3.3e-11 8.0e-12 4.1e-12
3 Brain gene expression ENSRNOG00000049349 0.15 0.06 0.0e+00 0.22 0.25 0.24 0.24 1.2e-20 2.6e-23 6.1e-22 5.0e-22
4 Brain mRNA stability ENSRNOG00000049349 0.17 0.05 0.0e+00 0.27 0.25 0.26 0.26 7.8e-25 4.8e-23 7.1e-24 3.7e-24
5 Eye gene expression ENSRNOG00000049349 0.7 0.17 1.8e-05 0.15 0.16 0.24 0.24 2.5e-03 2.1e-03 1.5e-04 1.4e-04
6 IL gene expression ENSRNOG00000049349 0.4 0.19 7.1e-06 0.24 0.18 0.22 0.21 2.2e-06 3.2e-05 5.6e-06 8.1e-06
7 LHb gene expression ENSRNOG00000049349 0.32 0.13 9.7e-08 0.28 0.29 0.27 0.29 1.9e-07 1.3e-07 3.2e-07 1.4e-07
8 LHb mRNA stability ENSRNOG00000049349 0.28 0.14 1.4e-05 0.15 0.21 0.2 0.23 2.6e-04 9.3e-06 2.1e-05 3.3e-06
9 NAcc gene expression ENSRNOG00000049349 0.24 0.11 3.0e-05 0.06 0.09 0.06 0.06 1.7e-05 6.4e-07 1.8e-05 2.4e-05
10 NAcc mRNA stability ENSRNOG00000049349 0.1 0.04 5.8e-10 0.07 0.13 0.12 0.12 5.6e-06 3.9e-10 1.6e-09 1.9e-09
11 OFC gene expression ENSRNOG00000049349 0.34 0.15 7.1e-05 0.14 0.16 0.13 0.14 2.7e-04 1.1e-04 4.6e-04 4.3e-04
12 OFC mRNA stability ENSRNOG00000049349 0.28 0.16 1.1e-03 0.04 0.04 -0 0.03 5.1e-02 5.0e-02 4.3e-01 8.0e-02
13 PL gene expression ENSRNOG00000049349 0.36 0.12 0.0e+00 0.29 0.27 0.27 0.27 3.3e-22 5.9e-21 5.7e-21 5.5e-21
14 PL mRNA stability ENSRNOG00000049349 0.18 0.08 9.6e-15 0.17 0.19 0.2 0.19 1.1e-12 1.0e-14 6.6e-15 3.2e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail4.715.230.1-3.5-3.1-3.8-3.5-5.5-3.8-4.1-4.0-4.0-3.9-3.0-4.0-3.7-3.9
BMI without tail2.65.49.3-2.1-2.1-2.4-1.9-3.0-2.3-2.5-2.4-2.1-2.5-1.9-2.4-2.3-2.3
Body weight3.012.724.7-3.2-2.9-3.7-3.2-5.0-3.4-3.8-3.9-3.8-3.7-2.7-3.6-3.3-3.4
Epididymis fat weight1.22.97.2-1.3-1.1-1.8-1.4-2.7-1.8-1.9-1.6-1.5-1.8-1.5-1.7-1.5-1.4
Glucose0.00.10.20.3-0.1-0.00.30.10.20.10.10.5-0.00.20.30.30.2
Heart weight0.10.10.5-0.10.70.6-0.10.5-0.20.40.5-0.30.6-0.2-0.1-0.00.2
Left kidney weight4.713.425.9-3.2-3.4-3.9-3.2-5.1-3.0-3.9-4.4-3.5-4.0-2.3-3.6-3.2-3.7
Right kidney weight7.521.536.6-4.1-4.5-5.1-4.1-6.0-4.1-5.1-5.2-4.0-5.1-3.6-4.7-4.0-4.7
Tail length0.30.91.80.90.60.81.01.31.00.90.81.00.80.81.10.91.1
Length with tail0.00.10.4-0.1-0.1-0.3-0.1-0.60.1-0.2-0.6-0.6-0.30.20.0-0.1-0.0
Length without tail1.32.85.8-1.6-1.1-1.5-1.8-2.4-1.4-1.6-1.8-2.1-1.5-1.2-1.7-1.5-1.6
Liver weight, left0.71.12.10.91.51.21.00.11.11.11.00.51.31.21.01.11.1
Liver weight, right0.30.61.90.70.60.50.8-0.51.20.60.10.20.51.40.90.80.7
Parametrial fat weight0.00.10.2-0.3-0.3-0.4-0.3-0.1-0.1-0.3-0.20.0-0.3-0.30.0-0.20.0
Retroperitoneal fat weight0.51.87.9-1.0-0.8-1.2-0.9-2.8-0.6-1.2-1.9-1.9-1.20.1-0.9-0.9-1.0
Intraocular pressure0.30.51.90.2-0.8-1.00.2-1.4-0.1-0.8-1.00.5-1.00.1-0.20.1-0.4
Extensor digitorum longus weight1.14.38.3-1.9-1.8-2.1-1.9-2.9-2.0-2.2-2.0-1.7-2.1-1.8-2.2-2.0-2.1
Soleus weight1.23.64.1-2.0-1.9-1.9-2.0-2.0-1.9-1.9-1.8-1.7-1.9-1.7-1.9-1.9-2.0
Tibialis anterior weight0.00.10.4-0.3-0.2-0.4-0.2-0.7-0.3-0.40.10.2-0.3-0.7-0.4-0.3-0.3
Tibia length1.33.86.02.02.32.12.00.72.12.01.50.92.12.42.02.12.1
Number of licking bursts0.40.41.00.10.81.00.11.00.30.90.5-0.51.00.70.50.20.3
Food consumed during 24 hour testing period8.910.712.6-3.3-3.0-3.2-3.4-3.1-3.2-3.3-3.6-3.4-3.2-2.8-3.4-3.5-3.4
Times rat made contact with spout2.42.74.3-1.9-1.5-1.4-2.0-1.3-1.5-1.5-1.8-2.1-1.4-1.2-1.7-1.8-1.8
Mean time between licks in bursts1.92.64.21.71.51.61.72.11.21.61.81.61.61.11.61.61.9
Mean num. licks in bursts1.21.53.2-0.9-1.3-1.5-0.9-1.8-0.9-1.4-1.4-0.6-1.5-0.9-1.2-1.0-1.1
Std. dev. time between licks in bursts0.10.10.30.20.40.40.20.30.10.30.60.50.4-0.10.10.40.3
Water consumed over 24 hours3.44.06.4-2.1-2.0-1.8-2.2-1.7-1.6-1.8-2.5-2.4-1.8-1.2-2.0-2.1-2.3
Indifference point 0 sec0.30.40.9-0.6-0.2-0.5-0.6-0.7-0.9-0.6-0.4-0.4-0.5-0.9-0.9-0.7-0.7
Indifference point AUC0.91.01.71.10.90.81.10.71.30.90.71.10.91.21.21.01.0
Indifference point function ln k4.56.48.1-2.4-2.5-2.7-2.4-2.8-2.5-2.7-2.7-2.0-2.7-2.3-2.6-2.4-2.5
Indifference point function log k4.56.48.1-2.4-2.5-2.7-2.4-2.8-2.5-2.7-2.7-2.0-2.7-2.3-2.6-2.4-2.5
Delay discounting total patch changes 0 sec0.00.10.2-0.10.30.0-0.1-0.4-0.5-0.10.10.10.0-0.5-0.4-0.2-0.1
Delay discounting total patch changes 12 sec0.00.10.2-0.3-0.1-0.1-0.20.1-0.3-0.1-0.3-0.3-0.1-0.2-0.3-0.4-0.4
Delay discounting total patch changes 18 sec0.91.21.71.21.21.11.20.80.91.10.80.61.11.31.21.21.2
Delay discounting total patch changes 24 sec1.01.21.81.31.41.01.30.11.11.00.91.11.01.11.11.21.3
Delay discounting total patch changes 6 sec0.10.10.40.20.50.30.10.60.10.30.50.40.4-0.20.10.10.2
Delay discounting time to switch 0 sec0.81.22.60.90.81.01.01.61.01.11.31.11.10.71.21.01.2
Delay discounting water rate 0 sec1.42.33.7-1.3-0.8-1.2-1.4-1.9-1.8-1.5-1.5-1.8-1.3-1.4-1.8-1.4-1.6
Delay discounting water rate 12 sec2.03.07.2-1.2-1.2-1.8-1.4-2.7-1.9-2.0-1.6-1.2-1.8-1.7-1.9-1.5-1.7
Delay discounting water rate 18 sec3.64.85.8-2.1-2.1-2.3-2.1-2.0-2.3-2.4-2.1-1.6-2.3-2.4-2.4-2.1-2.3
Delay discounting water rate 24 sec1.52.13.2-1.3-0.9-1.2-1.3-1.8-1.7-1.4-1.3-1.5-1.3-1.4-1.7-1.4-1.5
Delay discounting water rate 6 sec1.62.32.8-1.5-1.4-1.5-1.6-1.4-1.7-1.6-1.4-1.2-1.5-1.7-1.6-1.4-1.6
Locomotor activity0.30.52.1-0.4-0.4-0.6-0.3-1.4-0.5-0.6-1.0-1.1-0.70.3-0.4-0.2-0.5
Locomotor testing distance0.10.20.70.40.50.40.6-0.00.30.40.2-0.10.40.80.50.60.5
Locomotor testing rearing0.10.10.7-0.0-0.1-0.10.2-0.3-0.3-0.1-0.6-0.9-0.20.50.10.10.1
Light reinforcement 10.20.30.6-0.6-0.5-0.5-0.5-0.8-0.4-0.5-0.6-0.6-0.5-0.2-0.5-0.6-0.6
Light reinforcement 21.01.43.7-0.9-0.9-1.2-0.9-1.9-1.1-1.2-1.4-1.3-1.2-0.3-1.0-1.1-1.1
Reaction time number correct0.20.31.0-0.40.50.5-0.50.7-0.90.30.4-1.00.5-0.7-0.4-0.6-0.1
Reaction time mean minus median0.50.71.7-0.6-1.3-1.2-0.5-0.9-0.3-1.0-0.90.3-1.2-0.7-0.6-0.4-0.8
Reaction time mean minus median AUC0.50.61.5-0.5-1.2-1.1-0.4-0.8-0.4-1.0-0.80.1-1.1-0.7-0.6-0.4-0.7
Reaction time num false alarms0.00.00.10.2-0.0-0.00.30.00.20.0-0.10.2-0.00.30.30.30.1
Reaction time num false alarms AUC0.00.00.10.20.20.10.30.10.20.20.20.10.10.20.30.30.2
Reaction time trials correct on left0.20.31.0-0.40.50.5-0.50.7-0.90.30.4-1.00.5-0.7-0.4-0.6-0.1
Reaction time trials on left0.20.30.9-0.40.50.5-0.40.8-0.80.30.4-1.00.5-0.7-0.4-0.6-0.0
Reaction time mean0.60.92.40.90.60.71.01.21.10.81.11.60.70.40.91.00.8
Reaction time mean AUC0.81.02.61.00.70.81.01.31.10.91.21.60.80.51.01.00.9
Median of all reaction times1.41.93.21.31.31.21.41.71.41.31.61.81.30.71.31.31.3
Reaction time omissions2.53.35.41.41.92.01.32.31.72.02.31.52.11.21.81.51.8
Reaction time false alarm rate0.10.20.50.4-0.0-0.10.5-0.30.60.1-0.10.5-0.10.70.50.60.2
Reaction time premature initiation rate2.93.94.5-2.0-2.0-2.1-2.0-2.1-1.8-2.1-2.1-1.5-2.1-1.8-2.0-2.0-2.1
Reaction time premature initiations2.23.14.3-2.0-1.4-1.5-2.0-1.3-2.1-1.7-1.5-1.8-1.5-2.0-1.9-2.1-1.8
Std. dev. reaction times0.10.10.5-0.3-0.7-0.5-0.3-0.10.1-0.4-0.20.5-0.5-0.5-0.2-0.2-0.3
Reaction time trials completed0.20.30.9-0.40.50.5-0.40.8-0.80.30.4-1.00.5-0.7-0.4-0.6-0.0
Reaction time trials AUC0.30.41.1-0.50.30.2-0.60.5-1.10.00.2-1.10.2-0.9-0.6-0.8-0.2
Social response proportion0.00.00.1-0.3-0.2-0.1-0.2-0.30.1-0.1-0.3-0.3-0.10.1-0.1-0.3-0.2
Social responses0.30.41.2-0.6-1.1-0.8-0.5-0.7-0.1-0.7-0.9-0.2-0.8-0.1-0.3-0.5-0.7
Social time0.30.41.2-0.2-1.1-0.9-0.1-0.0-0.3-0.7-0.11.0-0.8-0.8-0.3-0.1-0.4
Conditioned locomotion0.20.31.3-0.4-0.5-0.6-0.4-1.1-0.2-0.6-0.50.3-0.6-0.4-0.4-0.5-0.3
Cocaine response after cond. corrected0.80.92.8-0.6-1.0-1.1-0.6-1.7-0.5-1.0-1.3-0.9-1.2-0.3-0.7-0.7-0.9
Cocaine response after cond. not corrected1.82.03.9-1.2-1.4-1.6-1.2-2.0-1.1-1.6-1.6-1.3-1.6-1.1-1.3-1.3-1.3
Cocaine response before conditioning0.70.81.9-1.0-0.7-0.8-1.0-0.4-1.2-0.9-0.4-0.6-0.8-1.4-1.0-1.1-0.6
Saline control response2.02.73.5-1.5-1.8-1.9-1.6-1.6-1.7-1.9-1.6-1.0-1.9-1.6-1.6-1.6-1.6
Condit. Reinf. active minus inactive responses0.20.21.3-0.1-0.3-0.6-0.1-1.1-0.3-0.6-0.6-0.3-0.6-0.1-0.4-0.1-0.2
Condit. Reinf. active-inactive response ratio0.10.20.70.0-0.2-0.50.0-0.8-0.4-0.5-0.4-0.2-0.5-0.3-0.4-0.2-0.1
Condit. Reinf. active responses0.81.13.7-0.7-0.8-1.1-0.7-1.9-0.8-1.2-1.2-1.0-1.2-0.5-0.9-0.7-0.7
Condit. Reinf. inactive responses1.21.52.9-1.2-1.2-1.3-1.2-1.7-0.9-1.3-1.5-1.3-1.3-0.7-1.1-1.1-1.1
Condit. Reinf. lever presses0.71.03.8-0.8-0.5-1.0-0.8-1.9-0.8-1.1-0.7-0.5-1.0-1.0-1.1-0.8-0.6
Condit. Reinf. lever reinforcers received0.71.03.3-0.7-0.8-1.1-0.7-1.8-0.8-1.2-1.2-1.0-1.2-0.6-1.0-0.7-0.7
Pavlov. Cond. lever latency1.11.52.51.20.81.21.31.61.31.30.91.01.21.51.41.20.9
Pavlov. Cond. magazine entry latency0.20.20.9-0.20.4-0.1-0.2-0.5-0.6-0.20.50.30.0-1.0-0.4-0.40.2
Pavlov. Cond. change in total contacts0.60.91.8-0.9-0.2-0.6-1.0-1.1-1.3-0.8-0.7-1.3-0.6-1.1-1.2-1.0-0.6
Pavlov. Cond. index score0.50.71.7-0.8-0.1-0.6-0.8-1.1-1.1-0.8-0.2-0.5-0.6-1.3-1.0-0.9-0.4
Pavlov. Cond. latency score1.01.22.7-1.1-0.5-1.0-1.2-1.3-1.4-1.2-0.5-0.8-0.9-1.7-1.3-1.3-0.7
Pavlov. Cond. lever contacts0.50.71.9-0.8-0.4-0.9-0.8-1.4-0.9-1.0-0.5-0.4-0.8-1.2-1.0-0.8-0.5
Pavlov. Cond. magazine entry number0.30.41.10.5-0.10.40.50.90.90.6-0.00.30.31.00.80.60.2
Pavlov. Cond. intertrial magazine entries0.81.02.21.20.80.91.10.51.50.90.60.70.81.41.11.20.9
Pavlov. Cond. lever-magazine prob. diff.0.30.41.3-0.70.0-0.5-0.7-0.9-0.9-0.6-0.0-0.4-0.4-1.2-0.8-0.7-0.2
Pavlov. Cond. response bias0.10.20.7-0.30.2-0.3-0.4-0.8-0.5-0.40.1-0.1-0.2-0.7-0.5-0.4-0.0
Conditioned reinforcement - actives1.21.22.5-0.7-1.6-1.6-0.9-1.0-0.5-1.3-1.2-0.1-1.6-1.0-0.7-0.8-0.9
Conditioned reinforcement - inactives0.50.62.0-0.1-0.8-1.1-0.4-1.4-0.4-0.9-0.9-0.2-1.1-0.5-0.5-0.5-0.7
Conditioned locomotion5.76.810.0-2.3-3.1-3.2-2.4-2.4-2.3-3.0-2.7-1.4-3.1-2.6-2.4-2.6-2.6
Intermittent access intake day 1-15 change4.34.27.0-2.1-2.6-2.4-1.9-1.7-1.9-2.2-2.2-1.4-2.4-1.9-1.8-1.9-2.0
Intermittent access intake escalation5.05.08.2-2.3-2.9-2.5-2.1-1.8-2.0-2.4-2.3-1.5-2.6-2.1-2.1-2.1-2.3
Intermittent access intake escalation 28.18.011.8-2.9-3.4-3.1-2.7-2.4-2.7-3.0-3.0-2.2-3.2-2.6-2.7-2.7-2.8
Intermitt. access day 1 inactive lever presses0.20.20.4-0.4-0.2-0.3-0.3-0.7-0.4-0.30.10.2-0.3-0.7-0.5-0.5-0.6
Intermitt. access day 15 inactive lever presses2.02.23.7-1.4-1.1-1.4-1.5-1.9-1.5-1.5-1.3-1.1-1.4-1.5-1.7-1.5-1.5
Intermitt. access escalation Index0.10.10.5-0.20.10.50.00.7-0.10.40.3-0.10.40.1-0.0-0.00.0
Intermittent access day 1 total infusions0.20.31.30.1-0.3-0.7-0.1-1.1-0.1-0.6-0.8-0.3-0.70.1-0.3-0.1-0.3
Intermittent access day 15 total infusions3.43.86.1-1.5-2.4-2.4-1.6-2.1-1.5-2.2-2.5-1.6-2.4-1.3-1.7-1.6-1.9
Intermittent access terminal intake (last 3 days)6.67.311.6-2.1-3.1-3.2-2.2-3.4-2.1-3.1-3.3-2.1-3.3-1.9-2.4-2.2-2.6
Intermittent access total infusions2.22.44.8-0.9-1.9-2.0-1.1-2.1-0.9-1.8-2.2-1.3-2.1-0.6-1.2-1.0-1.4
Intermittent access day 1 locomotion0.60.61.1-0.4-0.9-1.1-0.6-0.9-0.5-1.0-0.9-0.2-1.1-0.7-0.7-0.6-0.7
Intermittent access day 15 total locomotion3.94.26.0-1.9-2.3-2.4-1.9-2.2-1.6-2.3-2.3-1.6-2.5-1.7-1.9-1.9-2.0
Intermittent access total locomotion5.05.67.6-2.1-2.7-2.7-2.3-2.4-2.0-2.6-2.7-1.9-2.8-1.9-2.2-2.3-2.4
Intermittent access standard deviation6.26.69.7-2.4-3.1-2.9-2.6-1.9-2.4-2.7-2.7-2.0-2.9-2.4-2.3-2.7-2.7
Cocaine induced anxiety1.01.13.5-1.0-0.6-0.7-0.8-1.9-0.9-1.0-1.0-1.3-0.8-0.6-1.2-0.9-1.2
Post-drug Anxiety1.92.17.4-1.4-0.3-0.6-1.4-2.0-1.5-1.0-1.5-2.7-0.8-0.8-1.6-1.5-1.6
Baseline Anxiety0.30.30.80.60.70.60.30.90.50.70.40.20.60.50.60.50.6
Lifetime Intake1.51.63.7-0.5-1.6-1.7-0.7-1.9-0.6-1.5-1.9-1.0-1.8-0.2-0.8-0.7-1.1
Incentive Sensitization - Responses0.60.61.3-0.8-0.4-0.7-0.8-1.1-0.8-0.7-1.1-1.2-0.7-0.4-0.8-0.6-0.6
Incentive Sensitization - Breakpoint0.60.61.3-0.8-0.4-0.6-0.8-1.1-0.9-0.7-1.1-1.1-0.6-0.5-0.9-0.7-0.6
Progressive ratio test 1 active lever presses0.90.92.3-0.2-1.3-1.5-0.5-1.5-0.3-1.2-1.3-0.3-1.5-0.3-0.4-0.4-0.7
Progressive ratio test 1 breakpoint1.01.02.5-0.3-1.4-1.5-0.5-1.6-0.3-1.3-1.3-0.2-1.6-0.3-0.5-0.4-0.7
Progressive ratio test 1 inactive lever presses0.20.20.60.6-0.0-0.20.5-0.70.5-0.10.10.8-0.20.30.50.50.4
Progressive ratio test 2 active lever presses0.90.92.0-0.7-0.9-1.2-0.9-1.4-0.7-1.1-1.3-0.9-1.2-0.5-0.8-0.8-0.8
Progressive ratio test 2 breakpoint1.21.42.6-0.9-1.0-1.3-1.1-1.5-0.9-1.3-1.6-1.3-1.3-0.7-1.1-1.0-1.0
Progressive ratio test 2 inactive lever presses0.60.73.0-0.2-0.7-1.0-0.5-1.7-0.4-1.0-1.0-0.3-1.0-0.4-0.7-0.5-0.7
Total sessions with >9 infusions1.92.04.9-0.3-1.9-2.1-0.6-2.2-0.7-1.8-1.9-0.6-2.2-0.5-0.8-0.6-1.2
Short access day 1 total inactive lever presses4.24.66.0-1.8-2.3-2.4-1.9-2.4-2.1-2.4-2.0-1.3-2.5-2.2-2.3-1.9-2.4
Short access day 10 total inactive lever presses2.83.14.7-1.7-1.5-1.7-1.8-1.8-2.0-1.8-1.4-0.8-1.7-2.2-2.1-1.9-1.9
Short access day 1 total infusions0.40.41.70.3-0.5-0.80.2-1.3-0.0-0.7-0.9-0.5-0.90.4-0.00.1-0.3
Short access day 10 total infusions1.41.64.2-0.4-1.6-1.7-0.5-2.0-0.5-1.5-1.9-0.7-1.8-0.1-0.7-0.6-1.0
Short access total infusions0.80.93.50.2-1.0-1.2-0.0-1.9-0.1-1.0-1.5-0.7-1.40.4-0.2-0.1-0.6
Short access day 1 locomotion0.30.30.7-0.3-0.8-0.8-0.3-0.6-0.3-0.7-0.7-0.3-0.8-0.3-0.2-0.3-0.3
Short access day 10 total locomotion1.21.32.6-0.8-1.6-1.6-1.0-1.1-0.7-1.4-0.9-0.0-1.6-1.2-0.9-1.2-1.1
Short access total locomotion1.71.83.4-0.8-1.8-1.8-1.0-1.5-0.8-1.6-1.6-0.7-1.8-1.0-1.0-1.2-1.2
Compulsive drug intake0.20.21.0-0.4-0.4-0.0-0.31.0-0.4-0.10.30.50.0-0.8-0.5-0.3-0.3
One hour access (0.3 mA shock)0.91.02.2-0.6-1.5-1.4-0.8-0.8-0.5-1.2-1.5-0.7-1.4-0.4-0.6-0.7-0.9
One hour access (shock baseline)0.50.61.9-0.1-1.0-1.2-0.2-1.40.0-0.9-1.3-0.5-1.20.3-0.0-0.1-0.4
Number of responses in last shaping day0.20.21.00.7-0.3-0.10.7-0.10.70.10.21.0-0.10.50.60.40.2
Context. condit. distance diff. score0.40.52.2-0.5-0.5-0.8-0.5-1.5-0.3-0.8-0.50.3-0.7-0.7-0.8-0.4-0.6
Locomotion velocity, session 10.10.10.3-0.2-0.5-0.3-0.2-0.60.1-0.2-0.6-0.4-0.40.50.10.1-0.4
Locomotion distance, session 10.60.81.61.00.30.51.01.21.00.80.60.70.51.11.31.00.9
Locomotion velocity, session 20.80.91.4-0.9-1.0-0.9-0.9-1.1-0.6-0.9-1.2-1.2-1.0-0.3-0.8-0.9-1.2
Locomotion distance, session 20.60.91.40.90.81.00.91.20.91.00.90.51.01.01.00.90.8
Locomotion velocity, session 31.31.62.8-1.2-1.7-1.5-1.2-1.4-0.8-1.4-1.3-0.4-1.5-0.9-1.1-1.0-1.4
Locomotion distance, session 30.60.61.2-0.6-1.1-1.0-0.6-0.9-0.4-0.9-0.70.1-1.0-0.7-0.7-0.7-0.8
Stereotopy head waving bouts, day 30.60.81.10.70.81.00.70.90.91.00.80.41.01.01.00.90.8
Stereotopy head waving duration, day 30.10.20.50.30.10.30.30.40.50.40.20.10.30.70.60.50.3
Locomotion velocity, session 72.12.32.8-1.6-1.4-1.6-1.6-1.5-1.6-1.6-1.6-1.4-1.6-1.4-1.4-1.7-1.2
Locomotion distance, session 70.40.51.3-0.3-1.0-1.1-0.4-1.1-0.4-1.0-0.70.5-1.1-0.6-0.5-0.4-0.4
Stereotopy head waving bouts, day 70.30.30.90.70.10.30.7-0.10.80.40.21.00.20.80.60.70.2
Stereotopy head waving duration, day 70.40.50.80.80.60.70.90.30.80.70.60.60.70.90.70.70.6
Locomotion velocity, session 80.20.32.3-0.10.0-0.1-0.2-1.50.2-0.2-0.5-0.5-0.10.6-0.20.1-0.4
Locomotion distance, session 80.20.21.3-0.2-0.4-0.6-0.3-1.1-0.1-0.6-0.40.2-0.6-0.3-0.4-0.2-0.5
Degree of sensitization distance0.10.10.50.0-0.1-0.4-0.1-0.7-0.2-0.3-0.4-0.0-0.4-0.0-0.2-0.1-0.0
Degree of sensitization stereotypy0.10.10.30.4-0.00.20.5-0.10.50.20.00.60.10.60.30.40.0
Condit. Reinf. active minus inactive responses2.02.24.6-1.3-1.3-1.7-1.3-2.1-1.5-1.8-1.2-0.3-1.7-1.7-1.6-1.3-1.3
Condit. Reinf. active-inactive response ratio0.20.31.90.3-0.1-0.40.4-0.80.0-0.40.21.4-0.4-0.4-0.10.30.1
Condit. Reinf. active responses2.53.04.8-1.6-1.7-2.1-1.6-2.1-1.6-2.1-1.3-0.3-2.0-2.2-1.8-1.6-1.5
Condit. Reinf. inactive responses1.31.52.3-1.3-1.2-1.4-1.3-1.2-1.1-1.4-1.0-0.7-1.3-1.5-1.3-1.3-1.1
Incentive salience index mean3.94.77.6-2.0-2.1-2.4-2.0-2.8-2.1-2.5-2.0-1.1-2.4-2.3-2.2-2.0-1.9
Condit. Reinf. lever presses3.44.65.9-2.2-2.3-2.4-2.1-2.4-2.1-2.4-2.0-1.3-2.4-2.2-2.0-2.0-1.9
Time in familiar zone, hab. session 11.31.21.6-1.1-1.3-1.3-1.1-1.0-1.0-1.2-1.2-0.9-1.3-0.9-0.9-1.1-1.0
Time in novel zone, hab. session 12.42.43.21.61.81.71.61.01.51.61.61.31.71.51.31.61.5
Total zone transitions, hab. session 11.11.54.41.01.11.41.02.11.01.41.40.61.40.91.31.11.1
Total locomotion distance, hab. session 10.00.10.3-0.0-0.5-0.2-0.10.40.2-0.1-0.10.3-0.2-0.00.1-0.1-0.2
Locomotion velocity, hab. session 10.00.10.40.0-0.6-0.3-0.00.20.2-0.2-0.20.3-0.30.10.20.0-0.2
Time in familiar zone, hab. session 21.21.32.3-1.0-1.3-1.5-1.0-1.0-1.0-1.4-1.10.0-1.4-1.4-1.1-1.0-0.9
Time in novel zone, hab. session 21.61.62.61.11.41.61.21.11.11.51.40.51.61.31.11.21.0
Total zone transitions, hab. session 20.10.20.5-0.5-0.5-0.4-0.50.0-0.4-0.4-0.0-0.2-0.4-0.7-0.4-0.4-0.5
Total locomotion distance, hab. session 20.40.51.0-0.7-1.0-0.9-0.7-0.5-0.4-0.8-0.5-0.1-0.9-0.9-0.6-0.6-0.8
Locomotion velocity, hab. session 20.30.51.0-0.7-1.0-0.9-0.6-0.6-0.4-0.8-0.5-0.0-0.8-0.8-0.6-0.5-0.8
Novel to familiar place preference ratio0.00.00.20.00.30.3-0.00.1-0.20.20.1-0.40.30.0-0.1-0.2-0.1
Novelty place preference0.00.00.2-0.10.20.2-0.1-0.1-0.20.10.1-0.40.2-0.0-0.2-0.2-0.2
Time in novel zone, NPP test0.00.00.10.20.20.20.1-0.10.00.20.10.00.20.1-0.0-0.0-0.1
Total zone transitions, NPP test0.60.91.80.90.80.91.00.91.00.91.41.00.90.60.91.10.8
Total locomotion distance, NPP test0.10.10.80.1-0.6-0.40.2-0.20.3-0.20.10.9-0.4-0.20.10.3-0.2
Locomotion velocity, NPP test0.10.10.40.0-0.5-0.30.00.00.1-0.20.20.7-0.3-0.30.10.2-0.2
Pavlov. Cond. lever latency1.62.12.81.51.71.51.41.31.41.51.61.41.61.11.31.41.4
Pavlov. Cond. magazine entry latency0.20.20.4-0.5-0.6-0.6-0.5-0.1-0.4-0.5-0.30.1-0.5-0.6-0.3-0.4-0.3
Pavlov. Cond. change in total contacts1.61.72.2-1.4-1.5-1.4-1.3-1.0-1.2-1.4-1.4-1.2-1.4-1.2-1.3-1.2-1.3
Pavlov. Cond. index score0.60.81.1-1.1-1.1-0.9-1.0-0.5-0.9-0.9-0.9-0.8-0.9-0.8-0.7-0.9-0.8
Pavlov. Cond. latency score0.91.11.6-1.3-1.2-1.1-1.2-0.7-1.1-1.1-1.1-1.1-1.1-0.9-0.9-1.1-1.0
Pavlov. Cond. lever contacts2.73.14.0-1.8-2.0-1.9-1.7-1.8-1.7-1.9-2.0-1.8-1.9-1.3-1.5-1.6-1.7
Pavlov. Cond. magazine entry number0.20.30.60.70.80.70.60.30.50.60.50.10.70.60.50.50.5
Pavlov. Cond. intertrial magazine entries1.31.52.4-1.4-0.8-1.0-1.4-1.2-1.4-1.2-0.8-1.0-1.0-1.6-1.5-1.4-1.3
Pavlov. Cond. lever-magazine prob. diff.0.70.81.3-1.1-1.1-1.0-1.0-0.5-0.9-0.9-0.9-0.9-1.0-0.9-0.7-0.9-0.8
Pavlov. Cond. response bias1.31.62.4-1.3-1.5-1.5-1.2-1.4-1.1-1.4-1.4-0.8-1.5-1.1-1.1-1.1-1.1
Bone: apparent density0.30.51.80.60.50.60.61.40.30.70.90.60.70.20.80.50.9
Bone surface0.00.10.90.1-0.10.10.10.9-0.10.20.2-0.10.10.00.30.00.3
Bone volume0.10.31.60.30.10.30.31.30.10.40.50.20.40.20.60.30.7
Bone: connectivity density0.10.10.80.1-0.00.10.10.9-0.10.20.40.20.2-0.10.30.00.3
Bone: cortical apparent density2.53.36.01.32.12.31.22.41.32.22.31.32.31.21.51.31.7
Bone: cortical area0.10.21.7-0.10.1-0.3-0.1-1.3-0.4-0.4-0.4-0.4-0.3-0.2-0.3-0.2-0.0
Bone: cortical porosity0.10.20.60.30.20.20.3-0.80.50.1-0.2-0.20.10.80.30.40.1
Bone: cortical porosity0.20.21.00.30.10.00.4-1.00.50.1-0.20.1-0.00.70.30.50.0
Bone: cortical thickness0.10.20.60.20.80.50.20.10.00.40.60.30.6-0.00.10.20.5
Bone: cortical thickness0.20.31.2-0.50.1-0.3-0.5-1.1-0.6-0.4-0.2-0.2-0.2-0.7-0.7-0.5-0.2
Bone: cortical tissue density2.22.95.31.22.02.11.12.31.22.02.11.22.21.11.41.21.6
Bone: elastic displacement0.20.20.6-0.4-0.8-0.5-0.3-0.4-0.5-0.5-0.4-0.1-0.6-0.4-0.5-0.2-0.8
Bone: elastic work1.01.32.8-0.9-1.1-1.2-0.8-1.7-1.3-1.2-1.4-1.0-1.2-0.8-1.2-0.9-1.1
Bone: endosteal estimation0.71.54.7-0.8-1.4-1.5-0.7-2.2-0.8-1.4-1.7-0.9-1.5-0.3-0.9-0.7-1.1
Bone: endosteal perimeter0.91.97.0-0.8-1.2-1.5-0.8-2.6-0.9-1.5-2.1-1.4-1.6-0.1-1.0-0.8-1.1
Bone: final force0.81.32.41.11.61.11.2-0.21.01.01.31.01.20.80.91.21.4
Bone: final moment1.01.73.01.41.71.31.5-0.11.21.21.41.11.41.11.11.41.6
Bone: marrow area0.61.34.3-0.7-1.2-1.3-0.6-2.1-0.7-1.2-1.6-0.9-1.4-0.2-0.8-0.6-0.9
Bone: maximum diameter1.22.38.5-1.0-1.0-1.6-1.0-2.9-1.2-1.6-2.0-1.7-1.6-0.4-1.3-1.1-1.2
Bone: maximum force0.40.71.40.91.20.81.0-0.40.80.70.80.70.80.80.70.91.1
Bone: maximum moment0.61.01.81.11.31.01.2-0.30.90.90.90.81.01.00.91.11.3
Bone: minimum diameter0.20.43.70.1-0.4-0.80.1-1.9-0.1-0.7-0.80.1-0.80.1-0.10.1-0.1
Bone: periosteal estimation0.61.25.0-0.7-0.9-1.2-0.6-2.2-0.8-1.2-1.5-0.9-1.3-0.3-0.8-0.6-0.8
Bone: periosteal perimeter1.32.27.2-1.0-1.2-1.6-1.0-2.7-1.1-1.6-2.0-1.6-1.6-0.4-1.1-1.0-1.2
Bone: post-yield work1.52.03.41.31.91.61.31.11.21.51.40.81.61.31.41.21.7
Bone: stiffness1.62.53.91.62.01.61.61.11.51.61.81.51.71.11.41.51.9
Bone: tissue strength3.93.84.61.92.12.22.11.61.82.12.11.62.11.81.82.01.9
Bone: trabecular number0.20.31.10.60.00.20.60.80.40.40.71.00.30.20.70.50.7
Bone: trabecular spacing0.91.23.1-0.9-0.9-0.9-0.9-1.8-0.8-1.0-1.4-1.5-1.0-0.3-1.0-0.9-1.2
Bone: trabecular thickness0.00.10.1-0.2-0.3-0.2-0.10.2-0.4-0.2-0.1-0.0-0.2-0.4-0.1-0.3-0.0
Bone: trabecular tissue density4.76.68.72.32.92.92.42.42.42.83.02.22.92.12.42.42.7
Breakpoint value in progressive ratio session0.60.61.3-1.1-0.5-0.6-1.1-0.6-0.8-0.7-0.5-0.5-0.5-1.0-0.9-0.9-0.7
Distance traveled before self-admin0.70.71.60.90.60.71.00.51.00.80.50.60.71.31.10.90.8
Distance traveled after self-admin0.10.10.30.10.30.5-0.10.30.10.40.1-0.20.50.60.3-0.10.1
Delta time in closed arm before/after self-admin0.40.40.90.70.60.60.40.20.70.60.90.90.70.30.50.50.5
Delta time in open arm before/after self-admin0.20.20.6-0.3-0.8-0.5-0.20.3-0.2-0.4-0.5-0.3-0.5-0.2-0.2-0.3-0.5
Diff in mean of infusions in LGA sessions0.50.61.3-0.7-0.9-0.9-0.8-1.1-0.5-0.9-0.60.0-0.8-0.8-0.9-0.7-0.8
Extinction: sum of active levers before priming0.10.10.3-0.00.50.40.10.1-0.10.30.2-0.30.40.00.10.10.4
Active lever presses in extinction session 61.51.41.9-1.1-0.9-1.1-1.2-1.4-1.2-1.2-1.3-1.3-1.2-1.0-1.3-1.2-1.2
Delta distance traveled before/after self-admin1.31.42.3-1.3-0.9-1.0-1.5-0.9-1.3-1.1-1.0-1.0-1.0-1.3-1.4-1.5-1.2
Delta ambulatory time before/after self-admin1.61.82.7-1.4-1.0-1.1-1.6-1.1-1.5-1.2-1.2-1.5-1.1-1.3-1.5-1.6-1.5
Time in closed arm before self-admin0.20.30.8-0.4-0.7-0.5-0.40.2-0.6-0.4-0.9-0.9-0.50.0-0.3-0.4-0.4
Time in closed arm after self-admin0.20.20.40.6-0.5-0.50.3-0.60.2-0.3-0.30.7-0.50.30.20.3-0.1
Time in open arm before self-admin1.51.63.41.31.81.31.20.31.11.21.61.41.40.71.11.21.4
Time in open arm after self-admin0.20.20.6-0.00.70.70.10.70.10.60.7-0.00.7-0.10.10.00.3
Sum of active levers in priming session hrs 5-60.00.00.3-0.1-0.1-0.00.1-0.30.20.00.10.60.0-0.00.10.10.3
Time to tail flick, vehicle, before self-admin0.90.91.5-0.7-1.2-1.2-0.6-0.8-0.9-1.1-0.90.1-1.2-1.1-0.9-0.8-1.0
Time to tail flick, vehicle, after self-admin2.02.23.2-1.6-1.2-1.3-1.8-0.9-1.5-1.3-1.6-1.8-1.2-1.3-1.6-1.7-1.5
Time to tail flick, test, before self-admin0.20.20.80.2-0.6-0.7-0.0-0.90.0-0.6-0.70.3-0.70.1-0.1-0.0-0.2
Time to tail flick, test, after self-admin1.81.92.6-1.5-1.6-1.5-1.4-0.9-1.4-1.5-1.2-0.7-1.5-1.5-1.5-1.3-1.5
Delta time to tail flick, vehicle, before/after SA0.40.31.2-0.00.90.9-0.10.50.20.70.2-1.10.90.50.2-0.00.3
Delta time to tail flick, test, before/after SA0.50.51.3-1.0-0.6-0.4-0.80.3-0.8-0.5-0.0-0.5-0.4-1.1-0.8-0.7-0.7
Ambulatory time before self-admin0.20.20.40.40.30.40.40.40.50.50.40.30.50.60.60.40.4
Ambulatory time after self-admin0.60.71.6-1.0-0.5-0.4-1.1-0.2-1.0-0.5-0.7-1.3-0.4-0.5-0.8-1.2-0.9
Total heroin consumption0.10.10.6-0.00.4-0.0-0.0-0.8-0.2-0.1-0.1-0.1-0.0-0.2-0.3-0.00.1
Area under the delay curve1.11.21.91.11.31.21.01.30.81.11.10.61.20.81.21.01.4
Delay disc. indifference point, 0s delay0.30.30.7-0.2-0.8-0.8-0.3-0.8-0.6-0.7-0.9-0.2-0.8-0.3-0.4-0.4-0.4
Delay disc. indifference point, 16s delay0.40.41.00.50.60.70.41.00.50.70.70.50.70.20.70.30.6
Delay disc. indifference point, 2s delay2.32.54.31.81.41.51.71.21.71.61.00.81.42.12.01.81.8
Delay disc. indifference point, 24s delay2.52.43.3-1.6-1.2-1.4-1.8-0.9-1.7-1.5-1.5-1.5-1.3-1.8-1.7-1.8-1.6
Delay disc. indifference point, 4s delay1.61.73.11.51.31.21.31.81.01.31.31.21.20.81.41.21.6
Delay disc. indifference point, 8s delay0.60.61.70.71.31.00.51.00.10.80.9-0.21.00.20.70.51.1
Delay discount exponential model param1.21.32.0-1.2-1.4-1.2-1.0-1.3-0.8-1.2-1.2-0.6-1.3-0.8-1.2-1.0-1.4
Delay discount hyperbolic model param1.31.32.1-1.2-1.4-1.2-1.1-1.3-0.9-1.2-1.1-0.6-1.2-0.8-1.3-1.1-1.5
Fecal boli incidents, locomotor time 10.20.20.60.20.80.70.20.80.50.60.70.10.70.20.10.10.1
Change in fecal boli incidents, locomotor task0.30.30.6-0.7-0.7-0.6-0.7-0.2-0.7-0.6-0.4-0.4-0.6-0.5-0.4-0.6-0.5
Time >=10cm from walls, locomotor time 11.41.42.9-1.6-1.7-1.1-1.6-0.0-0.9-1.0-0.8-0.4-1.1-1.2-1.1-1.3-1.4
Bouts of movement, locomotor time 10.30.41.2-0.4-1.1-0.7-0.5-0.60.0-0.6-0.60.5-0.7-0.3-0.4-0.6-0.7
Total resting periods, locomotor time 10.10.21.0-0.1-0.8-0.3-0.1-0.00.5-0.1-0.11.0-0.3-0.10.1-0.2-0.3
Rest time, locomotor task time 10.10.10.20.3-0.10.1-0.00.30.50.20.20.50.10.20.30.0-0.0
Distance moved, locomotor task time 10.10.10.30.20.0-0.30.4-0.6-0.5-0.4-0.3-0.1-0.3-0.1-0.20.30.2
Vertical activity count, locomotor time 11.71.82.3-1.3-1.5-1.5-1.1-1.4-1.5-1.5-1.5-1.0-1.5-1.2-1.2-1.1-1.2
Time >=10cm from walls, locomotor time 24.85.17.6-2.7-2.4-1.9-2.8-0.8-2.4-2.0-1.8-2.0-1.9-2.5-2.4-2.7-2.4
Bouts of movement, locomotor time 21.31.32.20.71.01.50.71.41.11.51.10.61.51.21.30.91.2
Total resting periods, locomotor time 21.31.42.30.71.21.50.71.41.11.51.10.41.51.31.30.91.2
Rest time, locomotor task time 21.31.53.31.20.91.00.81.81.61.21.41.21.01.01.41.21.1
Distance moved, locomotor task time 22.73.15.9-1.4-1.4-1.8-1.2-2.4-2.3-2.0-1.8-1.4-1.8-1.8-2.0-1.5-1.6
Vertical activity count, locomotor time 24.85.28.7-1.9-1.8-2.3-1.9-2.9-2.8-2.4-2.4-2.0-2.3-2.2-2.5-2.0-2.1
Weight adjusted by age8.39.314.7-3.3-3.8-3.4-3.1-2.3-2.6-3.2-3.0-1.7-3.3-3.0-3.1-3.0-3.4
Seeking ratio, delayed vs. immediate footshock1.31.53.30.81.81.70.71.50.61.51.30.21.70.80.91.01.4
Locomotion in novel chamber0.10.20.6-0.7-0.6-0.3-0.5-0.0-0.0-0.30.20.4-0.2-0.8-0.4-0.3-0.4
Locomotion in novel chamber post-restriction2.12.55.01.61.31.31.70.91.81.41.52.21.41.61.61.71.6
Progressive ratio0.00.00.10.20.1-0.10.30.3-0.2-0.1-0.0-0.0-0.1-0.10.10.10.2
Food seeking constrained by brief footshock0.00.00.1-0.10.10.0-0.2-0.2-0.1-0.10.2-0.10.0-0.2-0.20.0-0.1
Seeking ratio, punishment vs. effort0.10.10.20.00.40.4-0.1-0.40.20.30.3-0.10.40.30.00.20.1
Run reversals in cocaine runway, females0.10.10.60.3-0.8-0.50.10.20.1-0.3-0.40.5-0.50.10.10.0-0.2
Run reversals in cocaine runway, males0.20.20.60.60.20.00.60.00.60.1-0.00.8-0.00.60.30.70.3
Latency to leave start box in cocaine runway0.10.10.9-0.20.0-0.2-0.3-1.0-0.1-0.2-0.4-0.2-0.20.1-0.4-0.2-0.4
Latency to leave start box in cocaine runway, F0.10.20.7-0.30.2-0.0-0.5-0.9-0.3-0.2-0.2-0.20.0-0.2-0.5-0.5-0.5
Latency to leave start box in cocaine runway, M0.10.10.50.1-0.1-0.00.1-0.40.30.0-0.5-0.4-0.10.70.30.40.2
Cd content in liver0.00.00.20.10.30.10.1-0.50.10.1-0.1-0.10.10.2-0.10.1-0.0
Co content in liver0.50.61.2-0.7-0.8-0.7-0.7-0.9-0.6-0.7-1.1-1.1-0.8-0.0-0.5-0.7-0.8
Cu content in liver2.53.06.31.12.12.21.12.51.22.12.30.62.30.81.61.22.0
Fe content in liver0.10.11.00.20.1-0.20.2-1.00.0-0.2-0.4-0.4-0.20.4-0.10.10.0
K content in liver0.20.20.50.10.70.7-0.00.60.30.60.7-0.20.70.20.30.20.5
Mg content in liver0.70.71.00.80.90.90.80.60.90.90.90.50.90.91.00.91.0
Mn content in liver0.10.10.4-0.0-0.40.0-0.10.60.30.2-0.10.10.00.30.30.1-0.1
Na content in liver1.92.02.81.31.71.61.31.41.21.61.40.71.61.31.51.31.6
Rb content in liver0.30.30.50.40.50.60.50.50.70.60.70.50.60.50.60.70.6
Se content in liver0.30.40.8-0.7-0.3-0.4-0.7-0.5-0.6-0.5-0.4-0.9-0.4-0.6-0.6-0.7-0.5
Sr content in liver0.20.20.90.10.40.50.11.00.10.50.4-0.20.50.10.40.10.4
Zn content in liver0.10.10.7-0.30.50.5-0.30.2-0.30.30.2-0.80.5-0.1-0.2-0.3-0.1