Syne4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000049277 0.08 0.05 4.0e-10 0.06 0.06 0.06 0.06 1.1e-07 4.3e-07 7.1e-07 2.4e-07
2 Brain gene expression ENSRNOG00000049277 0.3 0.1 0.0e+00 0.37 0.1 0.38 0.12 7.1e-36 9.0e-10 2.2e-37 8.0e-11
3 Brain isoform ratio ENSRNOT00000028265 0.2 0.09 1.1e-16 0.16 0.04 0.18 0.08 3.9e-15 2.5e-04 4.1e-16 1.2e-07
4 Brain isoform ratio ENSRNOT00000051422 0.22 0.1 0.0e+00 0.18 0.04 0.2 0.08 1.0e-16 1.5e-04 3.9e-18 1.1e-07
5 Brain intron excision ratio chr1:85570053:85570949 0.06 0.04 3.7e-03 0.01 0.01 0.02 0.02 2.5e-02 7.5e-02 4.8e-03 7.8e-03
6 Brain intron excision ratio chr1:85570053:85571283 0.23 0.11 0.0e+00 0.17 0.05 0.17 0.08 2.2e-15 1.3e-05 5.5e-16 1.1e-07
7 Brain intron excision ratio chr1:85571092:85571283 0.04 0.03 4.0e-04 0.04 0.01 0.03 0.01 1.9e-04 4.9e-02 6.4e-04 4.2e-02
8 Brain mRNA stability ENSRNOG00000049277 0.05 0.04 1.1e-03 0.01 0.01 0.03 0 1.9e-02 1.9e-02 1.4e-03 1.6e-01
9 LHb gene expression ENSRNOG00000049277 0.81 0.12 2.8e-09 0.27 0.04 0.21 0.08 4.0e-07 4.7e-02 1.1e-05 7.0e-03
10 LHb isoform ratio ENSRNOT00000028265 0.17 0.11 9.4e-04 0.08 -0.01 -0 -0.01 7.3e-03 5.6e-01 4.2e-01 7.4e-01
11 LHb isoform ratio ENSRNOT00000051422 0.14 0.1 5.0e-03 0.06 -0.01 -0.01 0 1.5e-02 6.5e-01 5.9e-01 2.9e-01
12 LHb intron excision ratio chr1:85570053:85571283 0.2 0.12 5.3e-04 0.08 0 0.1 0.05 6.8e-03 3.0e-01 3.0e-03 2.3e-02
13 Liver gene expression ENSRNOG00000049277 0.33 0.14 0.0e+00 0.23 0.26 0.26 0.25 2.5e-25 3.5e-28 3.8e-28 4.8e-28
14 Liver isoform ratio ENSRNOT00000028265 0.04 0.03 1.1e-05 0.04 0.04 0.03 0.04 6.8e-05 9.1e-05 1.2e-04 7.8e-05
15 Liver isoform ratio ENSRNOT00000051422 0.06 0.04 1.9e-07 0.05 0.05 0.04 0.04 5.6e-06 6.3e-06 8.7e-06 9.1e-06
16 Liver intron excision ratio chr1:85570053:85571283 0.1 0.07 8.9e-12 0.08 0.08 0.08 0.08 2.4e-09 2.1e-09 1.3e-09 3.0e-09
17 Liver intron excision ratio chr1:85571092:85571283 0.03 0.02 1.5e-04 0.02 0.02 0.02 0.02 1.4e-03 2.7e-03 4.3e-03 3.5e-03
18 Liver intron excision ratio chr1:85571477:85571553 0.02 0.02 4.6e-03 0.01 0.01 0.01 0.01 7.7e-03 1.3e-02 1.4e-02 1.2e-02
19 Liver intron excision ratio chr1:85571801:85572697 0.02 0.02 9.4e-03 0.01 0.01 0.01 0.01 1.3e-02 2.2e-02 2.7e-02 2.0e-02
20 Liver mRNA stability ENSRNOG00000049277 0.04 0.04 9.8e-04 0.01 0.02 0.02 0.02 2.0e-02 1.8e-03 1.1e-03 3.1e-03
21 NAcc gene expression ENSRNOG00000049277 0.06 0.04 3.7e-05 0.06 0.07 0.03 0.06 4.7e-05 1.2e-05 2.6e-03 5.4e-05
22 NAcc intron excision ratio chr1:85571092:85571283 0.05 0.04 1.1e-03 0.04 0.05 0.04 0.04 3.3e-04 2.2e-04 4.8e-04 7.5e-04
23 OFC gene expression ENSRNOG00000049277 0.33 0.22 3.4e-04 0.13 0.02 0.09 0.05 5.0e-04 1.0e-01 3.3e-03 3.1e-02
24 PL gene expression ENSRNOG00000049277 0.11 0.07 7.1e-08 0.1 0.09 0.1 0.1 3.6e-08 1.8e-07 4.0e-08 1.0e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
BMI with tail0.20.61.0-0.7-0.80.6-0.60.5-0.60.7-0.6-1.00.8-0.8-0.8-0.70.9-0.6-0.90.8-1.01.0-0.40.90.9-0.9-0.6
BMI without tail0.10.10.40.10.4-0.50.50.20.2-0.60.20.40.1-0.10.20.1-0.60.60.2-0.00.5-0.50.3-0.2-0.2-0.10.6
Body weight2.510.414.23.83.2-2.92.9-2.12.8-3.43.13.4-3.53.53.23.0-3.03.53.0-3.82.8-2.83.0-3.5-3.63.53.5
Epididymis fat weight0.10.20.60.70.3-0.30.2-0.40.5-0.30.50.6-0.70.70.50.60.00.30.3-0.8-0.00.00.5-0.5-0.50.60.3
Glucose0.20.41.1-0.1-0.50.9-0.91.0-1.00.5-0.9-0.20.2-0.2-0.7-0.80.5-0.5-0.60.0-0.70.7-0.80.40.1-0.2-0.5
Heart weight0.20.31.20.50.3-0.50.5-1.10.8-0.10.70.5-0.50.50.60.9-0.70.10.7-0.50.5-0.50.7-0.4-0.20.40.1
Left kidney weight2.26.411.13.22.7-1.71.8-1.02.1-2.62.12.7-3.23.22.62.1-2.22.52.2-3.22.2-2.21.8-3.0-3.33.12.5
Right kidney weight4.312.217.94.03.8-2.72.8-1.83.0-3.63.03.7-4.04.03.63.0-3.53.63.4-4.03.4-3.42.7-4.0-4.24.03.6
Tail length4.513.717.83.73.9-3.53.5-2.13.3-4.03.44.2-3.73.73.73.3-4.04.13.6-3.93.8-3.83.1-4.0-4.03.74.1
Length with tail7.828.633.25.65.4-5.05.1-3.95.0-5.65.25.7-5.65.65.45.1-5.25.75.3-5.85.1-5.14.9-5.7-5.75.65.7
Length without tail5.311.615.23.93.2-3.23.2-2.93.4-3.53.53.4-3.83.83.63.5-2.73.53.2-3.92.6-2.63.4-3.6-3.53.73.5
Liver weight, left0.71.12.5-0.6-0.71.3-1.21.6-1.20.8-1.3-0.70.8-0.8-1.0-1.31.2-0.9-1.10.6-1.21.2-1.40.70.4-0.8-0.9
Liver weight, right0.30.41.9-0.7-0.20.6-0.61.4-0.70.2-0.9-0.40.6-0.6-0.6-0.90.6-0.4-0.80.7-0.60.6-1.00.40.2-0.7-0.4
Parametrial fat weight0.51.06.8-0.4-0.21.3-1.22.6-1.40.1-1.40.10.3-0.3-0.8-1.51.0-0.3-1.10.2-1.01.0-1.70.1-0.6-0.4-0.3
Retroperitoneal fat weight1.75.89.2-1.7-2.23.0-3.02.9-2.82.3-2.7-1.81.7-1.7-2.4-2.72.7-2.4-2.61.5-2.72.7-2.92.01.4-1.9-2.4
Intraocular pressure0.00.00.3-0.0-0.2-0.20.2-0.50.20.20.2-0.30.1-0.10.00.3-0.2-0.20.30.20.2-0.20.20.10.3-0.0-0.2
Extensor digitorum longus weight0.20.82.0-0.2-0.91.3-1.31.3-1.40.8-1.2-0.60.4-0.4-1.0-1.20.8-0.8-1.00.3-0.90.9-1.20.60.2-0.4-0.8
Soleus weight0.10.41.4-0.4-0.50.4-0.50.8-0.70.3-0.6-0.40.6-0.6-0.6-0.71.1-0.2-0.80.6-1.21.2-0.60.50.3-0.5-0.2
Tibialis anterior weight0.10.41.60.3-0.50.9-0.91.3-1.20.2-0.9-0.3-0.20.2-0.6-0.90.5-0.2-0.6-0.2-0.50.5-0.90.1-0.40.2-0.2
Tibia length2.77.710.83.32.7-2.42.5-2.32.6-2.72.73.2-3.13.12.82.8-2.52.62.7-3.32.4-2.42.7-2.9-2.93.12.6
Number of licking bursts2.83.44.9-1.7-2.21.8-1.80.6-1.52.2-1.5-1.51.8-1.8-1.8-1.42.2-2.2-1.91.7-2.22.2-1.22.02.2-1.7-2.2
Food consumed during 24 hour testing period1.01.22.60.81.0-1.41.4-1.61.4-1.01.41.1-0.80.81.21.4-0.91.01.1-0.90.9-0.91.5-0.9-0.60.81.0
Times rat made contact with spout0.91.02.3-0.2-1.01.5-1.51.2-1.41.0-1.2-0.00.3-0.3-1.0-1.11.4-1.0-1.10.1-1.31.3-1.20.60.2-0.2-1.0
Mean time between licks in bursts0.10.10.3-0.40.3-0.40.4-0.20.5-0.20.3-0.20.2-0.20.20.2-0.40.20.10.40.3-0.30.20.00.3-0.40.2
Mean num. licks in bursts1.01.23.01.31.2-0.50.60.20.4-1.20.61.4-1.31.30.90.5-1.01.21.0-1.41.1-1.10.3-1.3-1.71.31.2
Std. dev. time between licks in bursts0.91.12.8-0.30.9-1.71.6-1.41.6-0.91.20.00.3-0.30.81.0-1.50.90.90.31.4-1.41.3-0.30.3-0.30.9
Water consumed over 24 hours0.40.50.90.80.6-0.60.6-0.60.6-0.70.70.9-0.70.70.70.7-0.30.70.6-0.90.3-0.30.7-0.8-0.80.80.7
Indifference point 0 sec0.10.20.7-0.00.5-0.70.7-0.40.8-0.50.60.20.1-0.10.40.4-0.10.50.2-0.00.1-0.10.5-0.3-0.1-0.00.5
Indifference point AUC0.40.50.8-0.7-0.60.5-0.50.8-0.70.4-0.8-0.50.9-0.9-0.8-0.90.8-0.5-0.80.7-0.80.8-0.70.70.6-0.8-0.5
Indifference point function ln k0.40.51.30.70.7-0.50.5-0.60.6-0.40.70.5-0.80.80.70.8-1.10.50.9-0.71.1-1.10.5-0.7-0.70.70.5
Indifference point function log k0.40.51.30.70.7-0.50.5-0.60.6-0.40.70.5-0.80.80.70.8-1.10.50.9-0.71.1-1.10.5-0.7-0.70.70.5
Delay discounting total patch changes 0 sec0.20.31.00.20.6-0.90.9-0.61.0-0.70.80.3-0.10.10.60.6-0.30.70.4-0.20.3-0.30.7-0.5-0.30.20.7
Delay discounting total patch changes 12 sec0.10.10.5-0.60.4-0.30.30.40.2-0.3-0.20.00.7-0.7-0.1-0.3-0.30.10.00.50.3-0.3-0.20.10.2-0.60.1
Delay discounting total patch changes 18 sec0.10.10.60.1-0.2-0.30.2-0.40.3-0.10.2-0.10.0-0.00.10.20.80.1-0.3-0.2-0.70.70.40.00.20.00.1
Delay discounting total patch changes 24 sec1.01.32.51.10.8-1.41.3-1.61.4-1.21.41.1-1.11.11.21.4-0.71.01.0-1.20.7-0.71.6-1.0-0.81.11.0
Delay discounting total patch changes 6 sec0.10.10.4-0.20.2-0.60.50.10.4-0.70.2-0.10.3-0.30.20.10.30.5-0.30.2-0.40.40.3-0.2-0.1-0.20.5
Delay discounting time to switch 0 sec0.61.01.7-1.2-0.61.0-0.91.3-1.10.9-1.1-0.91.1-1.1-1.0-1.20.5-0.9-0.81.3-0.50.5-1.30.90.8-1.1-0.9
Delay discounting water rate 0 sec0.61.02.2-1.0-1.10.6-0.70.6-0.70.7-0.8-1.11.1-1.1-0.9-0.81.4-0.7-1.30.9-1.51.5-0.61.01.1-1.0-0.7
Delay discounting water rate 12 sec0.60.91.71.30.6-0.70.6-1.21.2-0.71.11.1-1.21.21.01.2-0.50.70.7-1.30.5-0.51.2-1.0-0.91.20.7
Delay discounting water rate 18 sec0.10.20.5-0.5-0.40.3-0.40.4-0.30.3-0.3-0.20.4-0.4-0.5-0.40.7-0.2-0.60.4-0.70.7-0.30.40.4-0.5-0.2
Delay discounting water rate 24 sec0.20.32.10.3-0.2-0.60.5-1.40.80.10.7-0.0-0.40.40.40.90.1-0.00.2-0.2-0.20.21.00.00.40.2-0.0
Delay discounting water rate 6 sec1.31.93.71.31.1-1.51.5-1.91.8-1.31.81.2-1.41.41.51.8-0.91.31.1-1.30.9-0.91.9-1.3-0.91.41.3
Locomotor activity0.81.23.9-0.8-0.71.2-1.22.0-1.50.6-1.5-1.00.9-0.9-1.1-1.51.0-0.7-1.10.8-1.11.1-1.60.70.3-1.0-0.7
Locomotor testing distance0.50.92.2-0.6-0.81.1-1.11.5-1.40.7-1.2-1.00.6-0.6-1.0-1.20.9-0.8-0.90.7-1.01.0-1.20.70.3-0.6-0.8
Locomotor testing rearing2.03.14.7-1.2-2.02.1-2.11.7-2.01.8-1.8-1.91.2-1.2-1.8-1.82.1-1.8-2.01.3-2.22.2-1.71.61.3-1.2-1.8
Light reinforcement 10.10.10.6-0.2-0.30.1-0.1-0.20.10.3-0.0-0.30.5-0.5-0.2-0.10.8-0.2-0.40.3-0.70.70.10.40.5-0.4-0.2
Light reinforcement 22.63.44.5-2.0-1.71.7-1.71.5-1.61.8-1.7-1.92.1-2.1-1.9-1.81.9-1.7-1.92.1-1.91.9-1.71.91.9-2.1-1.7
Reaction time number correct0.10.10.40.1-0.30.2-0.20.3-0.3-0.1-0.10.0-0.10.1-0.2-0.10.60.1-0.5-0.1-0.60.6-0.10.0-0.10.00.1
Reaction time mean minus median0.50.61.20.80.9-0.70.7-0.50.9-0.80.80.9-1.11.11.00.7-0.20.60.5-0.90.3-0.30.6-0.9-0.90.90.6
Reaction time mean minus median AUC0.91.22.41.31.2-0.90.8-0.61.2-1.21.11.3-1.51.51.31.0-0.11.00.6-1.30.2-0.20.9-1.3-1.41.41.0
Reaction time num false alarms0.91.22.1-0.9-1.21.2-1.20.5-0.91.3-0.9-1.11.0-1.0-1.0-0.91.3-1.4-1.20.8-1.41.4-0.91.01.1-0.9-1.4
Reaction time num false alarms AUC1.11.52.4-1.1-1.21.3-1.30.7-1.01.3-1.1-1.21.2-1.2-1.1-1.11.4-1.6-1.31.0-1.51.5-1.11.21.2-1.1-1.6
Reaction time trials correct on left0.10.10.40.1-0.30.2-0.20.3-0.3-0.1-0.10.0-0.10.1-0.2-0.10.60.1-0.5-0.1-0.60.6-0.10.0-0.10.00.1
Reaction time trials on left0.10.10.50.1-0.30.2-0.30.3-0.3-0.1-0.10.0-0.10.1-0.2-0.20.70.1-0.5-0.1-0.60.6-0.10.0-0.10.10.1
Reaction time mean0.20.30.90.80.4-0.10.1-0.50.6-0.20.50.7-1.01.00.70.50.20.00.2-0.8-0.20.20.4-0.6-0.60.90.0
Reaction time mean AUC0.10.20.60.60.3-0.00.0-0.30.5-0.10.40.6-0.80.80.50.30.4-0.00.0-0.6-0.30.30.2-0.5-0.50.7-0.0
Median of all reaction times0.10.10.30.60.10.1-0.1-0.40.30.20.30.4-0.60.60.30.30.3-0.20.0-0.5-0.30.30.2-0.3-0.30.5-0.2
Reaction time omissions0.10.10.8-0.00.10.3-0.30.6-0.0-0.0-0.2-0.1-0.10.1-0.0-0.30.9-0.2-0.6-0.1-0.80.8-0.4-0.0-0.2-0.1-0.2
Reaction time false alarm rate0.60.81.7-0.9-0.90.9-0.90.3-0.61.1-0.8-1.01.0-1.0-0.8-0.80.7-1.3-0.80.8-0.90.9-0.81.01.0-0.9-1.3
Reaction time premature initiation rate0.20.31.2-0.20.4-1.11.0-0.80.8-0.60.70.20.2-0.20.30.6-0.30.70.40.30.3-0.30.8-0.10.3-0.20.7
Reaction time premature initiations0.10.20.8-0.10.2-0.90.8-0.60.6-0.60.60.10.2-0.20.20.50.20.60.10.2-0.10.10.7-0.10.2-0.20.6
Std. dev. reaction times0.81.02.31.30.9-0.80.7-1.01.2-0.81.11.1-1.51.51.31.1-0.10.60.6-1.30.2-0.21.0-1.1-1.11.30.6
Reaction time trials completed0.10.10.50.1-0.30.2-0.30.3-0.3-0.1-0.10.0-0.10.1-0.2-0.20.70.1-0.5-0.1-0.60.6-0.10.0-0.10.10.1
Reaction time trials AUC0.10.20.60.1-0.40.5-0.50.6-0.60.0-0.3-0.1-0.00.0-0.4-0.40.8-0.0-0.6-0.0-0.80.8-0.30.1-0.1-0.0-0.0
Social response proportion2.22.43.90.91.8-2.02.0-1.41.8-1.61.61.5-1.01.01.61.6-1.81.61.8-0.91.9-1.91.5-1.4-1.11.11.6
Social responses0.70.92.60.11.2-1.61.6-0.71.3-1.41.00.6-0.20.21.00.9-0.91.30.9-0.00.9-0.90.9-0.8-0.50.21.3
Social time3.14.16.11.91.9-2.32.3-2.52.4-2.02.41.9-2.02.02.22.3-1.61.92.1-1.81.6-1.62.3-1.9-1.61.91.9
Conditioned locomotion0.60.71.2-1.1-0.80.6-0.60.4-0.60.9-0.7-1.01.1-1.1-0.9-0.70.6-0.9-0.71.1-0.60.6-0.71.01.1-1.1-0.9
Cocaine response after cond. corrected0.20.31.7-0.5-0.00.6-0.51.3-0.70.2-0.7-0.30.5-0.5-0.5-0.8-0.2-0.2-0.30.40.1-0.1-0.90.2-0.0-0.5-0.2
Cocaine response after cond. not corrected0.30.32.5-0.30.20.6-0.51.6-0.8-0.0-0.8-0.30.2-0.2-0.4-0.9-0.10.0-0.30.30.1-0.1-1.00.0-0.4-0.20.0
Cocaine response before conditioning1.21.52.41.31.3-1.11.1-0.71.1-1.31.11.2-1.61.61.31.2-0.71.31.1-1.30.8-0.81.0-1.4-1.41.51.3
Saline control response0.00.00.2-0.0-0.10.1-0.00.4-0.5-0.2-0.2-0.30.0-0.0-0.1-0.2-0.30.20.00.10.3-0.3-0.2-0.0-0.20.00.2
Condit. Reinf. active minus inactive responses1.72.14.61.01.5-1.61.6-1.01.4-1.61.41.0-1.01.01.41.3-2.11.61.7-1.12.1-2.11.3-1.3-1.21.01.6
Condit. Reinf. active-inactive response ratio0.10.10.3-0.1-0.30.3-0.20.2-0.30.2-0.2-0.30.2-0.2-0.2-0.2-0.6-0.20.10.00.5-0.5-0.20.20.1-0.2-0.2
Condit. Reinf. active responses3.85.36.91.92.4-2.62.6-1.92.4-2.52.41.9-2.02.02.42.3-2.62.52.5-1.92.6-2.62.3-2.2-2.02.02.5
Condit. Reinf. inactive responses4.85.99.11.92.6-3.03.0-2.52.9-2.72.72.0-2.12.12.72.7-2.02.72.4-1.92.1-2.12.8-2.3-1.92.12.7
Condit. Reinf. lever presses7.19.811.82.93.4-3.23.3-2.13.0-3.43.03.3-2.92.93.12.9-3.43.43.3-2.93.4-3.42.8-3.2-3.12.93.4
Condit. Reinf. lever reinforcers received4.15.87.42.12.4-2.72.7-2.32.5-2.52.52.1-2.12.12.52.5-2.62.52.6-2.12.6-2.62.5-2.3-2.02.12.5
Pavlov. Cond. lever latency5.06.97.5-2.5-2.72.7-2.72.3-2.72.7-2.7-2.72.5-2.5-2.7-2.72.7-2.7-2.72.5-2.72.7-2.62.62.4-2.5-2.7
Pavlov. Cond. magazine entry latency2.83.34.61.42.0-2.02.0-1.42.0-1.91.81.9-1.31.31.81.8-2.11.91.9-1.42.1-2.11.7-1.8-1.61.41.9
Pavlov. Cond. change in total contacts8.712.114.13.43.4-3.53.5-3.53.7-3.33.73.3-3.23.23.63.7-3.83.33.7-3.33.8-3.83.6-3.4-3.03.33.3
Pavlov. Cond. index score5.16.77.92.42.7-2.62.6-2.32.7-2.62.72.8-2.42.42.72.7-2.72.62.7-2.42.8-2.82.6-2.6-2.42.52.6
Pavlov. Cond. latency score4.96.27.32.32.6-2.62.6-2.22.6-2.52.62.7-2.22.22.62.6-2.72.52.6-2.32.7-2.72.5-2.5-2.22.32.5
Pavlov. Cond. lever contacts4.66.47.72.52.5-2.52.5-2.42.6-2.52.62.8-2.52.52.62.6-2.62.52.6-2.52.6-2.62.6-2.5-2.32.52.5
Pavlov. Cond. magazine entry number3.94.86.2-2.3-2.22.0-2.01.9-2.12.1-2.2-2.52.2-2.2-2.2-2.22.3-2.1-2.32.3-2.42.4-2.12.22.1-2.3-2.1
Pavlov. Cond. intertrial magazine entries1.01.33.3-1.0-1.11.0-1.00.9-1.10.9-1.1-1.30.9-0.9-1.0-1.11.8-0.9-1.41.0-1.81.8-0.91.01.0-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.4.96.47.72.42.6-2.52.5-2.22.6-2.52.62.8-2.42.42.62.6-2.62.52.6-2.42.7-2.72.4-2.6-2.42.52.5
Pavlov. Cond. response bias5.47.48.62.72.6-2.72.7-2.72.8-2.62.92.9-2.72.72.82.9-2.82.62.9-2.72.8-2.82.8-2.7-2.42.72.6
Conditioned reinforcement - actives0.20.20.5-0.2-0.40.7-0.70.2-0.40.7-0.4-0.40.3-0.3-0.4-0.40.6-0.5-0.40.3-0.40.4-0.50.40.3-0.3-0.5
Conditioned reinforcement - inactives1.01.14.00.40.7-1.61.5-2.01.7-0.81.40.8-0.40.41.11.5-0.60.90.9-0.30.7-0.71.6-0.50.10.40.9
Conditioned locomotion2.02.33.9-1.6-1.71.3-1.30.4-1.11.9-1.2-1.71.6-1.6-1.5-1.11.7-1.6-1.41.7-1.61.6-1.11.82.0-1.6-1.6
Intermittent access intake day 1-15 change2.42.43.61.81.3-1.31.2-1.51.6-1.51.71.6-1.81.81.61.6-1.21.51.3-1.91.1-1.11.6-1.7-1.61.91.5
Intermittent access intake escalation2.42.43.51.81.3-1.31.3-1.61.6-1.41.71.6-1.81.81.71.7-1.21.41.3-1.91.0-1.01.6-1.6-1.51.81.4
Intermittent access intake escalation 21.61.62.11.41.3-1.01.0-0.91.2-1.11.31.4-1.41.41.31.2-1.41.31.3-1.41.2-1.21.1-1.4-1.41.41.3
Intermitt. access day 1 inactive lever presses3.74.05.91.32.3-2.42.4-1.52.3-2.32.02.3-1.31.32.12.0-2.32.22.1-1.32.3-2.31.9-1.9-1.61.42.2
Intermitt. access day 15 inactive lever presses0.70.72.00.20.9-1.31.2-1.21.4-0.81.00.8-0.20.20.91.0-1.00.60.9-0.11.0-1.01.0-0.5-0.10.20.6
Intermitt. access escalation Index0.10.10.3-0.1-0.50.1-0.1-0.6-0.20.4-0.0-0.60.1-0.1-0.20.10.2-0.4-0.10.0-0.30.30.10.30.5-0.1-0.4
Intermittent access day 1 total infusions1.82.04.0-1.4-1.71.2-1.3-0.0-1.01.9-1.1-1.71.4-1.4-1.3-0.81.6-1.8-1.21.3-1.51.5-0.81.72.0-1.4-1.8
Intermittent access day 15 total infusions0.20.22.00.1-0.2-0.20.2-1.40.70.50.5-0.1-0.20.20.30.7-0.0-0.50.3-0.2-0.10.10.70.20.60.1-0.5
Intermittent access terminal intake (last 3 days)0.20.21.1-0.4-0.50.1-0.2-1.00.30.90.1-0.50.3-0.3-0.10.30.1-0.70.00.3-0.20.20.30.61.0-0.4-0.7
Intermittent access total infusions0.40.51.4-0.5-0.80.4-0.5-0.8-0.01.2-0.2-0.80.5-0.5-0.40.10.5-1.1-0.30.5-0.50.5-0.00.81.2-0.5-1.1
Intermittent access day 1 locomotion0.70.82.6-1.1-1.00.1-0.2-0.7-0.11.1-0.3-1.01.1-1.1-0.7-0.20.9-1.0-0.61.1-0.80.80.01.21.6-1.1-1.0
Intermittent access day 15 total locomotion0.20.32.40.1-0.3-0.50.4-1.60.80.30.7-0.1-0.20.20.30.80.3-0.10.1-0.1-0.30.30.90.10.50.1-0.1
Intermittent access total locomotion0.91.02.5-1.2-1.20.6-0.6-0.3-0.41.3-0.6-1.11.1-1.1-0.9-0.51.0-1.1-0.81.1-1.01.0-0.41.21.6-1.2-1.1
Intermittent access standard deviation5.76.18.32.32.4-2.52.5-2.72.9-2.22.72.5-2.42.42.62.8-2.42.32.6-2.42.4-2.42.7-2.4-2.02.42.3
Cocaine induced anxiety0.50.61.10.50.9-0.90.9-0.30.5-1.00.60.8-0.50.50.70.5-1.10.90.8-0.50.9-0.90.6-0.7-0.70.50.9
Post-drug Anxiety0.10.20.5-0.70.20.00.00.7-0.20.0-0.40.00.7-0.7-0.2-0.5-0.2-0.2-0.10.70.3-0.3-0.50.30.3-0.7-0.2
Baseline Anxiety1.31.31.9-1.4-1.01.0-1.00.7-0.71.3-1.0-1.01.4-1.4-1.0-1.01.3-1.3-1.21.2-1.21.2-1.01.21.4-1.4-1.3
Lifetime Intake0.60.61.8-0.6-1.00.8-0.8-0.3-0.41.3-0.5-0.90.5-0.5-0.6-0.30.8-1.3-0.50.5-0.80.8-0.40.91.1-0.6-1.3
Incentive Sensitization - Responses0.10.10.80.0-0.40.5-0.5-0.5-0.20.9-0.2-0.4-0.00.0-0.20.1-0.1-0.80.2-0.10.1-0.1-0.10.30.30.0-0.8
Incentive Sensitization - Breakpoint0.10.10.80.1-0.40.6-0.5-0.4-0.20.9-0.2-0.4-0.10.1-0.20.10.0-0.80.1-0.10.1-0.1-0.20.20.30.1-0.8
Progressive ratio test 1 active lever presses0.70.83.00.80.4-1.00.9-1.71.1-0.41.10.5-0.80.80.91.3-0.50.61.0-0.80.7-0.71.3-0.5-0.20.80.6
Progressive ratio test 1 breakpoint1.11.13.01.00.7-1.21.2-1.71.2-0.61.30.8-1.01.01.11.4-0.80.91.2-1.01.1-1.11.4-0.8-0.51.00.9
Progressive ratio test 1 inactive lever presses0.80.82.80.30.6-1.41.3-1.71.4-0.61.20.7-0.40.40.91.3-0.70.70.9-0.30.8-0.81.4-0.50.10.40.7
Progressive ratio test 2 active lever presses0.20.21.40.3-0.1-0.00.0-1.20.40.60.4-0.1-0.30.30.30.6-0.2-0.40.5-0.30.4-0.40.40.00.30.3-0.4
Progressive ratio test 2 breakpoint0.10.11.10.2-0.20.1-0.1-1.00.30.70.2-0.2-0.20.20.10.5-0.1-0.50.4-0.20.3-0.30.30.10.30.2-0.5
Progressive ratio test 2 inactive lever presses1.51.76.90.40.8-1.71.7-2.61.8-0.41.50.6-0.40.41.21.8-1.70.51.7-0.31.8-1.81.7-0.50.30.30.5
Total sessions with >9 infusions1.21.32.2-0.9-1.11.2-1.30.9-1.11.3-1.1-1.10.9-0.9-1.1-1.11.5-1.2-1.20.9-1.51.5-1.01.11.0-0.9-1.2
Short access day 1 total inactive lever presses0.60.63.20.10.3-1.31.2-1.81.3-0.41.00.2-0.00.00.61.2-0.70.40.8-0.00.7-0.71.3-0.10.50.00.4
Short access day 10 total inactive lever presses1.71.93.60.81.3-1.71.7-1.51.6-1.21.41.1-0.80.81.31.5-1.91.21.7-0.81.9-1.91.4-1.1-0.80.91.2
Short access day 1 total infusions0.10.10.2-0.1-0.50.3-0.3-0.1-0.30.5-0.2-0.40.1-0.1-0.3-0.20.3-0.4-0.20.2-0.40.4-0.10.40.4-0.1-0.4
Short access day 10 total infusions0.40.41.0-0.4-0.70.8-0.80.2-0.61.0-0.6-0.70.4-0.4-0.6-0.50.8-0.9-0.50.4-0.70.7-0.50.70.7-0.4-0.9
Short access total infusions1.01.12.0-0.7-1.21.3-1.30.7-1.11.4-1.0-1.10.7-0.7-1.0-1.01.2-1.3-1.00.7-1.11.1-1.01.00.9-0.7-1.3
Short access day 1 locomotion0.40.41.7-0.5-0.60.5-0.50.3-0.20.4-0.3-0.30.4-0.4-0.4-0.41.3-0.3-0.90.4-1.31.3-0.20.50.5-0.4-0.3
Short access day 10 total locomotion1.01.12.60.40.9-1.61.5-1.51.5-1.11.30.9-0.50.51.01.3-1.01.11.1-0.41.1-1.11.4-0.7-0.30.51.1
Short access total locomotion0.80.81.3-1.1-0.90.5-0.60.4-0.50.8-0.7-0.81.1-1.1-0.8-0.81.1-0.8-0.91.1-1.01.0-0.61.01.1-1.1-0.8
Compulsive drug intake0.00.00.10.20.2-0.20.20.10.1-0.30.20.1-0.10.10.20.1-0.10.20.0-0.2-0.10.10.1-0.2-0.20.20.2
One hour access (0.3 mA shock)1.31.54.51.11.0-1.41.3-2.11.7-0.71.51.0-1.11.11.31.7-1.00.71.3-1.01.0-1.01.6-0.9-0.51.00.7
One hour access (shock baseline)0.20.21.70.20.1-0.40.3-1.30.70.20.50.1-0.20.20.40.7-0.2-0.20.5-0.10.3-0.30.6-0.00.30.1-0.2
Number of responses in last shaping day0.20.21.4-0.2-0.4-0.30.3-1.20.30.30.3-0.50.2-0.2-0.00.4-0.40.10.30.20.2-0.20.60.30.6-0.20.1
Context. condit. distance diff. score0.10.10.70.1-0.3-0.10.1-0.80.10.20.3-0.3-0.10.10.10.4-0.0-0.20.2-0.20.0-0.00.50.10.30.1-0.2
Locomotion velocity, session 10.70.82.0-0.5-0.91.1-1.11.2-1.40.8-1.1-0.70.5-0.5-1.0-1.10.9-0.8-0.90.7-0.80.8-1.10.70.4-0.5-0.8
Locomotion distance, session 10.60.81.51.00.5-1.01.0-1.20.7-0.91.00.7-1.01.00.81.0-0.70.90.9-0.90.6-0.61.2-0.8-0.61.00.9
Locomotion velocity, session 20.60.61.1-1.1-0.70.5-0.50.9-0.90.5-0.8-1.11.0-1.0-0.9-0.90.4-0.5-0.71.1-0.50.5-0.80.90.8-1.0-0.5
Locomotion distance, session 21.01.42.4-1.2-1.50.8-0.90.1-1.01.2-0.9-1.51.2-1.2-1.2-0.91.4-1.2-1.21.2-1.51.5-0.61.41.5-1.2-1.2
Locomotion velocity, session 30.30.30.5-0.4-0.60.7-0.70.3-0.50.7-0.5-0.60.4-0.4-0.5-0.50.6-0.7-0.60.5-0.70.7-0.50.50.5-0.4-0.7
Locomotion distance, session 33.43.76.91.61.7-2.22.2-2.62.5-1.62.41.3-1.51.52.12.4-2.01.62.1-1.61.9-1.92.4-1.7-1.11.51.6
Stereotopy head waving bouts, day 31.11.34.4-1.1-0.61.2-1.12.1-1.40.7-1.5-0.71.1-1.1-1.2-1.61.1-0.7-1.21.0-1.11.1-1.60.80.5-1.0-0.7
Stereotopy head waving duration, day 32.12.56.0-1.6-1.11.7-1.62.5-1.81.2-2.0-1.01.5-1.5-1.7-2.01.5-1.2-1.71.5-1.51.5-2.11.30.9-1.5-1.2
Locomotion velocity, session 70.50.51.50.70.3-1.00.9-1.20.8-0.71.00.3-0.70.70.70.9-0.40.70.7-0.70.3-0.31.1-0.5-0.30.70.7
Locomotion distance, session 70.20.20.60.70.1-0.30.3-0.60.2-0.30.50.0-0.70.70.50.5-0.20.30.4-0.80.1-0.10.5-0.5-0.50.70.3
Stereotopy head waving bouts, day 70.80.91.8-1.1-1.00.7-0.70.2-0.61.1-0.8-0.91.1-1.1-1.0-0.70.8-1.1-0.91.0-0.90.9-0.61.21.3-1.1-1.1
Stereotopy head waving duration, day 72.22.63.2-1.8-1.61.4-1.51.2-1.51.6-1.6-1.61.8-1.8-1.7-1.61.5-1.6-1.71.7-1.61.6-1.41.81.8-1.8-1.6
Locomotion velocity, session 83.34.05.6-2.0-2.31.7-1.70.8-1.72.1-1.6-2.32.1-2.1-1.9-1.62.2-2.1-2.01.9-2.42.4-1.32.22.4-2.1-2.1
Locomotion distance, session 80.50.71.8-0.7-1.20.4-0.5-0.8-0.41.0-0.2-1.30.7-0.7-0.6-0.20.9-1.0-0.60.6-1.01.00.11.01.3-0.7-1.0
Degree of sensitization distance0.70.71.8-0.4-0.81.2-1.11.2-1.30.7-1.1-0.50.3-0.3-0.9-1.11.0-0.7-0.90.4-0.90.9-1.10.60.2-0.3-0.7
Degree of sensitization stereotypy1.01.12.3-1.1-1.20.7-0.8-0.0-0.61.2-0.7-1.11.2-1.2-1.0-0.71.0-1.2-1.01.1-1.11.1-0.41.31.5-1.2-1.2
Condit. Reinf. active minus inactive responses0.20.20.4-0.6-0.40.4-0.40.4-0.30.5-0.5-0.40.6-0.6-0.5-0.50.3-0.5-0.40.6-0.10.1-0.50.50.6-0.6-0.5
Condit. Reinf. active-inactive response ratio0.40.41.6-0.8-0.10.6-0.51.3-0.50.4-0.8-0.20.9-0.9-0.6-0.90.2-0.4-0.60.8-0.20.2-1.00.50.3-0.9-0.4
Condit. Reinf. active responses1.92.33.4-1.8-1.71.3-1.30.8-1.41.6-1.4-1.71.7-1.7-1.6-1.41.4-1.6-1.41.8-1.21.2-1.31.81.8-1.7-1.6
Condit. Reinf. inactive responses1.82.13.9-1.6-1.91.1-1.20.0-1.31.7-1.0-1.91.4-1.4-1.5-1.01.5-1.7-1.31.6-1.41.4-0.81.72.0-1.4-1.7
Incentive salience index mean0.20.20.5-0.7-0.30.1-0.20.2-0.10.4-0.3-0.50.7-0.7-0.4-0.40.1-0.4-0.30.70.0-0.0-0.30.50.7-0.7-0.4
Condit. Reinf. lever presses0.10.10.4-0.30.3-0.60.6-0.40.5-0.20.3-0.10.3-0.30.20.3-0.50.20.30.40.5-0.50.40.10.3-0.30.2
Time in familiar zone, hab. session 10.30.31.10.90.30.10.00.4-0.2-0.50.10.7-0.80.80.20.1-0.50.50.4-0.80.5-0.5-0.0-0.7-1.00.90.5
Time in novel zone, hab. session 11.21.12.6-1.6-0.80.5-0.60.1-0.21.1-0.6-1.11.5-1.5-0.8-0.61.0-1.1-1.01.5-1.01.0-0.51.21.6-1.5-1.1
Total zone transitions, hab. session 10.00.10.40.0-0.2-0.30.3-0.6-0.0-0.10.2-0.2-0.00.0-0.00.2-0.20.10.30.00.2-0.20.40.10.30.00.1
Total locomotion distance, hab. session 11.11.62.90.71.4-1.71.7-1.01.3-1.41.21.1-0.80.81.21.2-1.71.41.5-0.61.6-1.61.2-1.1-0.90.81.4
Locomotion velocity, hab. session 10.60.91.80.51.1-1.31.3-0.50.8-1.20.80.8-0.60.60.80.8-1.31.21.1-0.41.2-1.20.8-0.8-0.80.61.2
Time in familiar zone, hab. session 21.81.93.30.91.8-1.61.6-0.41.3-1.81.21.3-0.90.91.31.0-1.61.81.3-0.71.7-1.71.0-1.4-1.50.91.8
Time in novel zone, hab. session 21.31.32.2-0.8-1.31.4-1.40.7-1.11.5-1.1-0.90.8-0.8-1.1-1.01.4-1.5-1.10.6-1.41.4-1.01.11.1-0.8-1.5
Total zone transitions, hab. session 22.73.55.1-2.1-2.01.5-1.61.2-1.71.8-1.8-2.12.1-2.1-2.0-1.81.6-1.8-1.92.3-1.81.8-1.52.12.2-2.1-1.8
Total locomotion distance, hab. session 20.10.20.7-0.8-0.2-0.30.3-0.20.10.1-0.1-0.30.7-0.7-0.3-0.10.0-0.1-0.20.9-0.20.20.10.50.8-0.7-0.1
Locomotion velocity, hab. session 20.20.20.9-0.9-0.3-0.20.10.0-0.10.2-0.3-0.50.7-0.7-0.4-0.30.2-0.2-0.40.9-0.30.3-0.10.60.8-0.7-0.2
Novel to familiar place preference ratio0.20.20.40.40.4-0.40.4-0.60.6-0.20.50.4-0.30.30.50.5-0.50.20.4-0.40.3-0.30.5-0.3-0.20.30.2
Novelty place preference0.10.10.40.30.3-0.30.2-0.60.5-0.10.50.3-0.20.20.40.5-0.40.10.3-0.40.2-0.20.5-0.2-0.10.30.1
Time in novel zone, NPP test0.00.00.30.20.0-0.10.0-0.50.30.10.30.1-0.10.10.20.3-0.2-0.10.1-0.3-0.00.00.3-0.00.10.1-0.1
Total zone transitions, NPP test0.10.10.4-0.1-0.40.2-0.20.1-0.50.1-0.3-0.40.0-0.0-0.3-0.20.5-0.1-0.30.1-0.60.6-0.10.30.2-0.1-0.1
Total locomotion distance, NPP test2.12.93.91.61.9-1.91.9-1.11.5-2.01.51.7-1.71.71.71.6-1.72.01.7-1.61.6-1.61.5-1.8-1.81.72.0
Locomotion velocity, NPP test2.23.24.41.62.0-2.02.0-1.01.6-2.11.61.8-1.71.71.71.6-1.82.11.8-1.61.7-1.71.5-1.9-1.91.72.1
Pavlov. Cond. lever latency0.20.20.80.80.3-0.00.1-0.30.2-0.20.40.5-0.70.70.40.4-0.40.20.5-0.90.4-0.40.3-0.5-0.70.70.2
Pavlov. Cond. magazine entry latency0.40.60.8-0.9-0.60.7-0.70.9-0.70.6-0.8-0.60.8-0.8-0.8-0.90.8-0.6-0.90.9-0.80.8-0.80.70.7-0.8-0.6
Pavlov. Cond. change in total contacts0.20.20.9-0.8-0.4-0.20.1-0.2-0.00.2-0.1-0.60.8-0.8-0.3-0.20.2-0.2-0.30.8-0.20.20.10.70.9-0.8-0.2
Pavlov. Cond. index score0.50.71.4-1.2-0.60.5-0.50.9-0.60.5-0.8-0.81.1-1.1-0.8-0.90.8-0.5-0.91.2-0.80.8-0.70.90.9-1.1-0.5
Pavlov. Cond. latency score0.30.31.0-1.0-0.40.1-0.20.5-0.30.3-0.5-0.60.8-0.8-0.5-0.60.4-0.3-0.61.0-0.40.4-0.40.70.8-0.8-0.3
Pavlov. Cond. lever contacts0.10.10.4-0.50.3-0.60.60.00.4-0.40.2-0.20.4-0.40.20.1-0.30.40.10.50.3-0.30.20.00.2-0.40.4
Pavlov. Cond. magazine entry number0.60.71.11.00.7-0.70.7-0.90.8-0.70.90.7-0.90.90.90.9-0.90.71.0-1.00.9-0.90.8-0.9-0.90.90.7
Pavlov. Cond. intertrial magazine entries0.70.81.5-0.8-1.21.0-1.00.6-1.21.0-0.9-1.20.9-0.9-1.0-0.90.4-1.0-0.70.7-0.30.3-0.91.00.9-0.9-1.0
Pavlov. Cond. lever-magazine prob. diff.0.70.81.7-1.3-0.70.5-0.60.9-0.70.6-0.9-0.91.2-1.2-0.9-1.00.9-0.6-1.01.3-0.90.9-0.81.01.1-1.2-0.6
Pavlov. Cond. response bias0.20.30.8-0.7-0.20.3-0.30.9-0.50.2-0.6-0.40.7-0.7-0.5-0.70.4-0.2-0.60.8-0.40.4-0.70.50.4-0.7-0.2
Bone: apparent density0.50.81.81.21.0-0.60.6-0.00.5-1.10.61.3-1.21.20.80.6-0.21.10.6-1.20.3-0.30.5-1.1-1.41.21.1
Bone surface1.62.83.61.81.6-1.81.8-1.51.6-1.81.71.8-1.81.81.81.8-1.01.81.5-1.81.1-1.11.8-1.8-1.71.91.8
Bone volume1.52.53.91.91.5-1.41.4-1.21.3-1.61.51.8-1.91.91.61.6-0.91.61.4-1.91.0-1.01.5-1.7-1.82.01.6
Bone: connectivity density0.20.40.70.60.7-0.70.7-0.20.5-0.80.50.7-0.60.60.60.50.10.80.3-0.60.0-0.00.5-0.7-0.70.70.8
Bone: cortical apparent density1.92.53.7-1.3-1.81.7-1.80.8-1.61.9-1.4-1.71.4-1.4-1.5-1.31.9-1.9-1.61.3-1.71.7-1.31.61.6-1.3-1.9
Bone: cortical area1.11.72.31.51.4-1.21.2-0.81.1-1.41.21.4-1.31.31.41.2-1.21.41.3-1.41.3-1.31.1-1.5-1.51.41.4
Bone: cortical porosity1.41.52.9-1.6-1.00.6-0.70.2-0.31.1-0.7-1.11.5-1.5-1.0-0.81.6-1.1-1.41.5-1.61.6-0.61.41.7-1.5-1.1
Bone: cortical porosity1.71.93.7-1.7-1.30.7-0.80.2-0.51.3-0.8-1.31.7-1.7-1.2-0.91.7-1.3-1.51.7-1.71.7-0.71.61.9-1.6-1.3
Bone: cortical thickness0.20.30.70.70.6-0.30.30.10.3-0.60.30.7-0.60.60.50.3-0.40.60.4-0.60.6-0.60.2-0.7-0.80.60.6
Bone: cortical thickness0.91.11.6-0.8-1.01.2-1.21.2-1.20.9-1.2-0.80.9-0.9-1.1-1.21.2-0.9-1.10.9-1.11.1-1.20.90.7-0.9-0.9
Bone: cortical tissue density2.22.94.1-1.4-2.01.8-1.90.8-1.72.0-1.5-1.91.5-1.5-1.7-1.42.0-2.0-1.71.4-1.91.9-1.41.71.7-1.4-2.0
Bone: elastic displacement0.10.10.30.10.00.4-0.40.5-0.30.2-0.3-0.00.1-0.1-0.1-0.30.3-0.2-0.2-0.1-0.30.3-0.5-0.0-0.2-0.1-0.2
Bone: elastic work1.52.03.11.51.6-1.31.3-0.81.3-1.51.31.8-1.41.41.41.3-1.41.51.4-1.51.4-1.41.1-1.5-1.61.41.5
Bone: endosteal estimation1.73.74.61.81.9-2.12.1-1.61.9-2.12.01.9-1.81.81.91.9-2.02.12.0-1.81.8-1.82.0-1.9-1.81.82.1
Bone: endosteal perimeter1.63.34.41.71.8-2.02.0-1.91.9-1.81.91.6-1.61.61.92.0-2.11.82.0-1.62.0-2.01.9-1.8-1.51.61.8
Bone: final force1.52.53.81.51.6-1.71.7-1.31.7-1.71.61.9-1.41.41.71.6-1.31.71.5-1.51.4-1.41.6-1.6-1.51.51.7
Bone: final moment2.03.24.31.81.8-1.81.9-1.41.8-1.91.82.1-1.71.71.91.8-1.61.91.7-1.81.7-1.71.8-1.9-1.81.81.9
Bone: marrow area1.83.84.81.81.9-2.12.1-1.61.9-2.22.01.9-1.81.81.91.9-2.02.22.0-1.81.8-1.82.0-2.0-1.91.82.2
Bone: maximum diameter1.32.32.91.61.7-1.51.5-1.21.6-1.61.51.7-1.41.41.61.5-1.41.61.5-1.51.4-1.41.4-1.6-1.61.51.6
Bone: maximum force2.54.36.12.12.1-2.12.1-1.82.2-2.22.12.5-1.91.92.22.1-1.92.22.1-2.11.9-1.92.1-2.2-2.02.12.2
Bone: maximum moment3.05.26.52.32.3-2.32.3-1.92.3-2.42.32.6-2.22.22.42.3-2.22.42.3-2.32.2-2.22.2-2.4-2.22.32.4
Bone: minimum diameter3.56.58.22.22.4-2.92.9-2.62.7-2.62.72.2-2.12.12.62.7-2.82.62.7-2.12.8-2.82.8-2.4-2.02.22.6
Bone: periosteal estimation2.04.04.72.12.1-2.02.0-1.51.9-2.22.02.1-1.91.92.11.9-2.02.22.0-2.01.9-1.91.9-2.1-2.12.02.2
Bone: periosteal perimeter1.22.03.41.41.6-1.31.4-0.91.2-1.41.31.3-1.21.21.41.3-1.91.51.6-1.31.8-1.81.1-1.5-1.51.31.5
Bone: post-yield work2.12.94.71.51.6-2.12.0-2.22.1-1.72.01.6-1.41.41.82.0-1.51.71.7-1.41.4-1.42.2-1.5-1.11.41.7
Bone: stiffness1.32.12.91.31.4-1.51.5-1.31.5-1.51.51.7-1.41.41.51.5-1.41.51.5-1.41.4-1.41.5-1.4-1.31.51.5
Bone: tissue strength3.73.65.51.71.9-2.12.1-2.12.3-1.92.22.0-1.71.72.12.2-1.71.91.8-1.81.6-1.62.2-1.8-1.51.71.9
Bone: trabecular number1.42.23.31.61.6-1.51.5-1.21.4-1.61.51.8-1.61.61.51.5-0.91.61.4-1.61.0-1.01.5-1.6-1.61.71.6
Bone: trabecular spacing0.20.20.90.10.7-0.40.40.30.4-0.60.20.3-0.10.10.30.1-1.00.60.4-0.10.9-0.9-0.0-0.4-0.50.00.6
Bone: trabecular thickness0.10.10.50.3-0.40.6-0.60.1-0.40.4-0.20.0-0.30.3-0.2-0.20.7-0.4-0.4-0.3-0.60.6-0.10.1-0.00.3-0.4
Bone: trabecular tissue density3.14.48.0-1.4-2.02.8-2.72.8-2.82.1-2.6-1.71.5-1.5-2.2-2.51.9-2.1-2.11.3-1.91.9-2.71.71.0-1.4-2.1
Breakpoint value in progressive ratio session2.02.24.80.71.5-1.91.9-1.71.6-1.41.41.1-0.80.81.31.6-2.21.41.9-1.02.1-2.11.6-1.1-0.70.61.4
Distance traveled before self-admin0.10.10.60.10.00.00.0-0.0-0.40.1-0.1-0.3-0.10.1-0.2-0.0-0.70.20.6-0.20.8-0.8-0.10.1-0.10.10.2
Distance traveled after self-admin4.24.75.62.12.2-2.32.4-1.82.1-2.22.12.1-2.02.02.22.2-2.12.32.3-2.12.3-2.32.2-2.1-1.92.12.3
Delta time in closed arm before/after self-admin2.52.43.51.71.6-1.41.5-1.01.4-1.61.51.9-1.61.61.51.5-1.51.51.5-1.71.5-1.51.4-1.7-1.81.71.5
Delta time in open arm before/after self-admin0.80.81.5-0.8-0.70.8-0.91.2-0.70.5-0.8-1.00.7-0.7-0.8-0.91.0-0.4-1.21.0-1.21.2-0.80.80.7-0.8-0.4
Diff in mean of infusions in LGA sessions0.30.41.1-1.0-0.5-0.10.1-0.4-0.30.5-0.3-1.00.9-0.9-0.6-0.2-0.4-0.20.10.90.4-0.40.00.81.1-1.0-0.2
Extinction: sum of active levers before priming3.33.44.51.91.9-1.61.7-1.01.5-1.81.52.0-2.02.01.71.6-2.11.82.1-2.12.1-2.11.5-2.0-2.01.91.8
Active lever presses in extinction session 62.22.24.11.41.8-1.11.2-0.10.6-1.60.91.6-1.41.41.30.9-1.91.71.7-1.61.9-1.90.6-1.7-2.01.41.7
Delta distance traveled before/after self-admin4.85.16.42.22.3-2.52.5-1.92.5-2.52.42.3-2.22.22.52.4-1.72.42.0-2.31.8-1.82.5-2.4-2.12.22.4
Delta ambulatory time before/after self-admin5.45.97.92.42.4-2.72.6-2.22.8-2.62.72.6-2.42.42.72.7-1.62.52.1-2.51.7-1.72.7-2.6-2.32.42.5
Time in closed arm before self-admin2.32.63.8-1.6-1.71.5-1.50.7-1.41.8-1.5-1.81.6-1.6-1.5-1.31.7-2.0-1.51.7-1.61.6-1.31.81.9-1.6-2.0
Time in closed arm after self-admin0.10.20.7-0.00.3-0.50.5-0.60.30.00.20.20.1-0.10.20.3-0.7-0.10.70.10.8-0.80.20.00.2-0.0-0.1
Time in open arm before self-admin4.34.67.22.12.3-2.02.1-1.22.0-2.32.12.7-2.02.02.11.8-2.02.52.1-2.22.1-2.11.7-2.4-2.52.12.5
Time in open arm after self-admin1.11.22.41.11.2-0.90.8-0.21.1-1.51.11.2-1.11.11.10.9-0.51.50.5-1.20.4-0.40.9-1.3-1.41.11.5
Sum of active levers in priming session hrs 5-60.20.20.40.40.3-0.40.4-0.40.2-0.40.30.3-0.40.40.30.4-0.60.30.7-0.70.6-0.60.4-0.3-0.40.40.3
Time to tail flick, vehicle, before self-admin1.11.12.2-1.0-1.11.0-1.00.5-0.91.0-1.0-1.11.0-1.0-1.0-0.91.0-1.5-0.91.1-1.01.0-1.01.11.1-1.0-1.5
Time to tail flick, vehicle, after self-admin0.10.10.3-0.50.3-0.20.20.2-0.0-0.0-0.1-0.00.4-0.40.0-0.1-0.50.10.20.50.5-0.5-0.20.10.1-0.50.1
Time to tail flick, test, before self-admin0.40.41.80.0-0.70.2-0.3-0.90.20.60.1-0.4-0.00.0-0.10.31.3-0.9-0.6-0.1-1.31.30.40.50.8-0.0-0.9
Time to tail flick, test, after self-admin0.10.10.60.1-0.20.1-0.1-0.20.2-0.00.20.10.0-0.0-0.00.10.80.1-0.4-0.1-0.80.80.2-0.00.10.00.1
Delta time to tail flick, vehicle, before/after SA0.70.71.60.51.0-1.01.0-0.40.9-1.00.91.0-0.60.60.90.8-0.71.30.7-0.50.8-0.80.8-0.8-0.70.51.3
Delta time to tail flick, test, before/after SA0.40.42.0-0.6-0.30.6-0.51.4-0.90.0-0.7-0.30.7-0.7-0.7-0.90.40.3-0.60.7-0.30.3-0.90.2-0.1-0.60.3
Ambulatory time before self-admin0.10.10.4-0.2-0.0-0.10.10.0-0.30.1-0.1-0.40.2-0.2-0.2-0.1-0.70.20.40.10.7-0.7-0.10.20.1-0.10.2
Ambulatory time after self-admin8.08.811.02.82.9-3.33.3-2.73.1-3.13.12.9-2.72.73.13.2-2.83.13.1-2.92.9-2.93.2-2.9-2.62.83.1
Total heroin consumption0.50.61.50.40.8-1.01.0-1.20.8-0.40.70.3-0.50.50.60.9-1.10.71.2-0.61.1-1.10.9-0.5-0.20.30.7
Area under the delay curve0.50.61.20.10.8-1.11.1-1.11.1-0.60.80.8-0.00.00.70.8-1.00.60.9-0.31.0-1.00.9-0.4-0.0-0.10.6
Delay disc. indifference point, 0s delay0.50.53.50.30.1-0.90.9-1.90.7-0.10.80.1-0.20.20.40.9-0.70.30.9-0.30.8-0.81.20.00.40.20.3
Delay disc. indifference point, 16s delay1.11.23.10.21.3-1.31.3-1.31.6-0.61.11.2-0.10.11.11.2-1.80.61.4-0.21.6-1.61.0-0.7-0.20.00.6
Delay disc. indifference point, 2s delay1.21.43.11.10.9-1.51.4-1.81.3-1.11.40.9-1.11.11.21.5-0.81.11.2-1.30.9-0.91.6-0.9-0.60.91.1
Delay disc. indifference point, 24s delay2.82.74.21.11.7-2.12.0-1.72.0-1.81.81.7-1.11.11.81.8-1.81.61.7-1.21.7-1.71.8-1.5-1.11.21.6
Delay disc. indifference point, 4s delay0.10.10.4-0.50.1-0.40.4-0.40.40.00.10.00.6-0.6-0.10.1-0.3-0.10.10.40.2-0.20.30.30.6-0.6-0.1
Delay disc. indifference point, 8s delay0.30.30.60.30.7-0.70.7-0.50.7-0.60.60.7-0.10.10.50.5-0.40.60.5-0.40.5-0.50.6-0.4-0.30.10.6
Delay discount exponential model param0.60.71.4-0.2-1.01.2-1.11.0-1.20.8-0.9-0.90.1-0.1-0.8-0.91.0-0.7-0.90.4-1.01.0-1.00.50.2-0.1-0.7
Delay discount hyperbolic model param0.50.51.2-0.2-0.81.1-1.01.0-1.10.7-0.8-0.80.1-0.1-0.7-0.80.8-0.6-0.80.4-0.80.8-0.90.40.1-0.0-0.6
Fecal boli incidents, locomotor time 12.32.54.2-2.0-1.21.3-1.21.6-1.51.5-1.7-1.62.0-2.0-1.7-1.70.9-1.5-1.22.0-1.01.0-1.81.61.6-2.0-1.5
Change in fecal boli incidents, locomotor task0.20.10.60.00.4-0.10.10.80.0-0.5-0.00.60.1-0.10.1-0.3-0.30.80.1-0.10.4-0.4-0.2-0.3-0.50.10.8
Time >=10cm from walls, locomotor time 10.10.10.2-0.3-0.10.4-0.40.3-0.00.4-0.30.20.2-0.2-0.1-0.3-0.1-0.3-0.20.2-0.10.1-0.30.20.1-0.3-0.3
Bouts of movement, locomotor time 10.80.93.30.70.6-1.21.2-1.81.1-0.61.20.6-0.60.60.91.3-1.00.81.2-0.81.0-1.01.4-0.6-0.30.60.8
Total resting periods, locomotor time 10.70.82.50.50.6-1.01.1-1.61.0-0.51.00.5-0.40.40.71.1-1.10.81.2-0.71.1-1.11.1-0.5-0.20.40.8
Rest time, locomotor task time 11.11.22.6-1.5-0.90.7-0.71.0-1.10.9-1.1-1.01.6-1.6-1.4-1.20.3-0.6-0.71.4-0.30.3-1.11.21.2-1.5-0.6
Distance moved, locomotor task time 10.20.20.70.7-0.10.2-0.2-0.60.10.10.4-0.0-0.70.70.40.40.4-0.10.0-0.9-0.40.40.4-0.3-0.30.7-0.1
Vertical activity count, locomotor time 12.22.33.41.61.4-1.61.5-1.51.6-1.61.81.2-1.61.61.71.7-0.91.71.1-1.60.9-0.91.8-1.6-1.41.51.7
Time >=10cm from walls, locomotor time 21.71.83.0-1.7-1.41.1-1.10.9-1.21.5-1.4-1.51.7-1.7-1.5-1.40.9-1.1-1.21.5-1.01.0-1.21.51.6-1.6-1.1
Bouts of movement, locomotor time 20.00.00.20.2-0.10.3-0.3-0.2-0.10.40.00.3-0.10.1-0.00.1-0.1-0.00.2-0.20.1-0.10.00.10.00.1-0.0
Total resting periods, locomotor time 20.00.00.2-0.1-0.10.3-0.30.1-0.30.4-0.10.10.2-0.2-0.2-0.1-0.00.0-0.00.1-0.00.0-0.20.20.2-0.20.0
Rest time, locomotor task time 20.50.61.4-1.2-0.50.4-0.41.0-0.70.4-0.7-0.61.2-1.2-0.9-0.80.2-0.3-0.61.1-0.20.2-0.80.80.8-1.1-0.3
Distance moved, locomotor task time 20.20.21.00.3-0.50.3-0.3-0.5-0.10.30.1-0.4-0.20.2-0.10.01.0-0.3-0.5-0.5-0.90.90.20.20.20.2-0.3
Vertical activity count, locomotor time 21.01.12.01.20.7-1.01.0-1.41.1-0.91.30.8-1.11.11.11.2-0.61.00.8-1.30.6-0.61.4-1.0-0.81.11.0
Weight adjusted by age0.10.10.40.60.20.2-0.20.10.2-0.00.20.7-0.30.30.20.20.4-0.1-0.2-0.6-0.50.50.1-0.3-0.40.3-0.1
Seeking ratio, delayed vs. immediate footshock1.51.84.31.21.2-1.41.4-2.11.7-1.01.61.3-1.31.31.51.6-1.30.61.4-1.11.2-1.21.5-1.1-0.81.30.6
Locomotion in novel chamber0.30.41.0-1.0-0.20.1-0.10.8-0.50.1-0.7-0.71.0-1.0-0.6-0.7-0.1-0.3-0.21.00.1-0.1-0.70.60.5-0.9-0.3
Locomotion in novel chamber post-restriction0.20.21.2-0.50.3-0.60.60.1-0.0-0.3-0.0-0.00.3-0.3-0.1-0.0-1.10.30.60.61.0-1.0-0.10.10.1-0.20.3
Progressive ratio0.10.10.3-0.10.4-0.60.60.00.2-0.40.1-0.00.1-0.10.10.1-0.30.40.30.20.2-0.20.2-0.00.1-0.30.4
Food seeking constrained by brief footshock3.23.95.01.72.2-2.22.2-1.52.0-2.22.02.0-1.81.82.12.0-2.12.12.2-1.72.2-2.21.8-2.0-1.81.72.1
Seeking ratio, punishment vs. effort0.50.71.00.80.7-0.70.7-1.00.9-0.60.90.9-0.80.80.91.0-0.70.70.8-0.80.8-0.80.8-0.8-0.71.00.7
Run reversals in cocaine runway, females0.70.71.51.20.5-0.60.6-1.10.9-0.81.00.7-1.01.00.91.00.10.40.4-1.2-0.00.01.1-0.8-0.71.10.4
Run reversals in cocaine runway, males0.60.64.2-0.50.11.0-1.02.1-0.80.1-0.90.20.4-0.4-0.5-1.20.4-0.1-0.80.5-0.50.5-1.30.1-0.4-0.3-0.1
Latency to leave start box in cocaine runway0.30.31.20.7-0.0-0.50.4-1.10.6-0.30.70.0-0.80.80.40.80.20.30.3-0.7-0.00.00.9-0.3-0.20.80.3
Latency to leave start box in cocaine runway, F0.10.10.50.2-0.2-0.20.2-0.70.4-0.10.5-0.0-0.20.20.20.40.60.1-0.2-0.3-0.50.50.6-0.00.20.20.1
Latency to leave start box in cocaine runway, M0.10.10.50.5-0.1-0.10.0-0.4-0.0-0.10.2-0.2-0.70.70.10.20.00.10.2-0.40.0-0.00.3-0.2-0.30.60.1
Cd content in liver0.10.10.40.60.00.2-0.2-0.0-0.1-0.00.00.4-0.60.60.10.10.20.00.0-0.5-0.20.20.0-0.3-0.40.50.0
Co content in liver0.30.40.7-0.7-0.50.4-0.40.7-0.50.3-0.6-0.70.8-0.8-0.6-0.70.7-0.3-0.70.7-0.60.6-0.50.60.6-0.8-0.3
Cu content in liver0.50.60.90.80.8-0.80.8-0.70.8-0.80.80.8-0.90.90.80.8-0.40.90.6-0.90.3-0.30.9-0.8-0.70.80.9
Fe content in liver0.00.00.1-0.2-0.10.0-0.0-0.00.00.2-0.0-0.10.1-0.1-0.1-0.00.1-0.1-0.00.2-0.10.1-0.00.20.2-0.2-0.1
K content in liver0.10.10.3-0.40.4-0.40.40.00.5-0.30.2-0.10.3-0.30.20.1-0.30.30.00.30.3-0.30.1-0.10.1-0.30.3
Mg content in liver0.70.71.5-1.2-0.40.5-0.61.1-0.50.5-0.8-0.91.2-1.2-0.7-0.90.7-0.5-0.91.2-0.70.7-0.90.80.8-1.2-0.5
Mn content in liver1.31.53.0-1.4-0.81.1-1.11.7-1.20.9-1.4-1.01.4-1.4-1.2-1.51.2-0.8-1.41.5-1.11.1-1.51.10.9-1.4-0.8
Na content in liver1.92.03.61.21.2-1.41.4-1.61.6-1.21.51.0-1.31.31.41.5-1.91.21.6-1.21.9-1.91.5-1.2-1.01.31.2
Rb content in liver0.10.10.4-0.6-0.1-0.30.2-0.40.40.20.1-0.40.5-0.5-0.00.10.1-0.1-0.10.5-0.10.10.30.30.7-0.5-0.1
Se content in liver8.210.011.1-3.3-3.03.1-3.13.0-3.13.1-3.2-3.03.1-3.1-3.2-3.33.3-3.1-3.33.2-3.23.2-3.23.12.9-3.2-3.1
Sr content in liver1.00.91.4-1.0-0.80.9-0.91.1-1.10.8-1.0-0.81.2-1.2-1.0-1.10.8-0.8-0.91.0-0.80.8-1.10.90.7-1.0-0.8
Zn content in liver0.10.10.3-0.5-0.2-0.0-0.00.3-0.0-0.0-0.2-0.30.4-0.4-0.2-0.30.3-0.0-0.40.5-0.40.4-0.10.30.4-0.5-0.0