Hub : Genes

Bysl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000049121 0.08 0.05 5.4e-07 0.03 0.04 0.04 0.04 5.8e-04 8.2e-05 1.5e-05 7.0e-05
2 Adipose mRNA stability ENSRNOG00000049121 0.17 0.09 1.3e-09 0.08 0.09 0.08 0.08 7.2e-09 8.5e-10 5.2e-09 3.5e-09
3 BLA gene expression ENSRNOG00000049121 0.37 0.13 0.0e+00 0.36 0.35 0.34 0.35 2.1e-20 1.2e-19 7.2e-19 1.5e-19
4 BLA mRNA stability ENSRNOG00000049121 0.05 0.04 4.1e-03 0.01 0.03 0.01 0.01 1.2e-01 1.3e-02 9.9e-02 1.1e-01
5 Brain gene expression ENSRNOG00000049121 0.05 0.03 1.1e-04 0.05 0.04 0.03 0.04 3.0e-05 9.9e-05 1.2e-03 9.7e-05
6 Eye gene expression ENSRNOG00000049121 0.36 0.19 2.4e-03 0.04 0.11 -0.01 0.08 7.2e-02 1.1e-02 6.1e-01 2.1e-02
7 IL gene expression ENSRNOG00000049121 0.26 0.14 8.3e-04 0.08 0.12 0.11 0.11 5.7e-03 1.1e-03 1.5e-03 1.2e-03
8 LHb gene expression ENSRNOG00000049121 0.28 0.14 6.2e-05 0.1 0.2 0.3 0.16 1.9e-03 2.1e-05 6.0e-08 1.2e-04
9 Liver gene expression ENSRNOG00000049121 0.06 0.03 5.2e-07 0.02 0.04 0.03 0.04 1.6e-03 3.7e-05 3.8e-04 5.4e-05
10 NAcc gene expression ENSRNOG00000049121 0.15 0.07 1.1e-11 0.13 0.15 0.13 0.15 6.0e-10 4.5e-11 1.2e-09 5.3e-11
11 OFC gene expression ENSRNOG00000049121 0.45 0.16 2.6e-06 0.19 0.28 0.18 0.22 2.7e-05 2.5e-07 4.1e-05 5.1e-06
12 PL gene expression ENSRNOG00000049121 0.22 0.09 4.1e-15 0.17 0.18 0.19 0.18 2.6e-13 2.4e-13 3.6e-14 1.2e-13
13 PL mRNA stability ENSRNOG00000049121 0.04 0.02 2.2e-03 0.01 0.03 0.01 0.01 3.8e-02 2.0e-03 2.8e-02 2.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.96.214.30.41.60.4-3.83.73.51.82.43.31.30.41.3-3.7
BMI without tail5.311.228.11.02.30.4-4.95.34.72.72.54.52.11.01.9-4.8
Body weight1.35.613.30.21.30.8-3.63.63.21.72.53.01.40.21.5-3.4
Epididymis fat weight1.02.35.70.81.00.5-1.92.41.81.70.61.81.50.81.7-1.8
Glucose2.74.19.31.12.11.0-2.53.12.61.80.22.71.71.51.5-2.4
Heart weight1.11.62.7-1.6-1.5-0.90.8-1.2-1.1-1.60.3-1.2-1.5-1.6-1.40.8
Left kidney weight1.23.59.0-3.0-0.9-2.2-1.80.51.1-2.01.60.8-2.0-2.6-2.1-1.9
Right kidney weight1.13.28.2-2.9-1.2-2.6-1.30.10.6-2.10.60.3-2.1-2.7-2.1-1.4
Tail length0.61.75.70.40.70.2-2.02.41.91.00.51.80.70.30.6-1.9
Length with tail0.10.41.1-1.1-0.7-0.4-0.50.50.2-0.60.70.1-0.6-1.1-0.5-0.5
Length without tail1.83.86.9-1.8-2.2-0.82.1-2.6-2.4-2.1-0.3-2.5-1.8-1.8-1.62.0
Liver weight, left0.61.02.2-1.20.0-0.7-1.51.01.1-0.61.11.0-0.7-1.0-0.7-1.5
Liver weight, right0.30.51.1-0.00.5-0.2-1.01.01.00.1-0.91.00.00.0-0.1-1.0
Parametrial fat weight2.85.512.90.82.11.6-3.23.63.11.81.13.21.71.21.5-3.1
Retroperitoneal fat weight0.82.56.4-1.6-0.3-1.2-2.52.32.0-0.5-0.21.7-0.8-1.6-0.8-2.5
Intraocular pressure0.20.31.3-0.40.10.30.8-1.1-0.8-0.50.2-0.7-0.1-0.1-0.30.7
Extensor digitorum longus weight0.20.61.60.41.0-0.3-1.00.71.00.51.21.00.50.30.2-1.0
Soleus weight0.30.92.2-0.21.3-0.5-1.41.21.4-0.10.11.50.00.2-0.5-1.5
Tibialis anterior weight0.10.40.80.30.80.6-0.80.90.80.60.50.80.60.50.5-0.7
Tibia length1.02.86.9-0.31.0-0.6-2.52.62.40.2-1.92.4-0.0-0.0-0.5-2.5
Number of licking bursts4.55.38.72.32.62.7-1.52.11.82.71.82.12.82.62.9-1.4
Food consumed during 24 hour testing period0.40.40.9-0.7-0.3-0.7-0.90.80.7-0.3-0.90.6-0.6-0.7-0.5-0.8
Times rat made contact with spout4.85.57.22.12.71.6-2.22.52.42.62.52.52.52.22.5-2.1
Mean time between licks in bursts1.31.84.20.9-0.51.72.0-1.5-1.80.31.3-1.60.50.80.92.1
Mean num. licks in bursts0.70.82.3-0.9-0.8-1.50.3-0.8-0.4-1.1-0.1-0.6-1.1-1.2-1.30.2
Std. dev. time between licks in bursts1.01.32.6-0.5-1.20.01.5-1.6-1.5-0.90.9-1.6-0.8-0.6-0.41.5
Water consumed over 24 hours1.01.13.0-0.40.1-1.0-1.71.61.50.20.61.4-0.2-0.5-0.1-1.7
Indifference point 0 sec0.40.61.30.50.41.1-0.81.00.81.00.30.80.80.51.1-0.7
Indifference point AUC1.21.42.7-1.5-0.3-1.6-1.20.81.0-1.20.30.9-1.4-1.3-1.6-1.3
Indifference point function ln k0.10.20.6-0.0-0.3-0.10.5-0.8-0.50.00.8-0.60.1-0.10.30.4
Indifference point function log k0.10.20.6-0.0-0.3-0.10.5-0.8-0.50.00.8-0.60.1-0.10.30.4
Delay discounting total patch changes 0 sec0.50.81.30.50.61.1-1.01.11.01.00.40.90.80.61.1-0.9
Delay discounting total patch changes 12 sec0.70.92.0-0.80.1-1.0-1.40.91.2-0.5-0.61.1-0.7-0.8-0.9-1.4
Delay discounting total patch changes 18 sec0.60.81.9-0.80.2-0.5-1.41.21.2-0.40.11.1-0.6-0.6-0.8-1.3
Delay discounting total patch changes 24 sec0.30.42.0-0.5-0.3-0.0-0.80.60.6-0.21.40.5-0.4-0.6-0.3-0.7
Delay discounting total patch changes 6 sec1.01.63.60.31.20.2-1.91.71.90.90.41.80.70.40.6-1.9
Delay discounting time to switch 0 sec1.92.97.20.2-0.91.02.7-2.5-2.5-0.4-1.7-2.4-0.10.20.12.7
Delay discounting water rate 0 sec2.03.26.1-1.7-0.3-2.5-2.41.72.0-1.01.41.7-1.5-1.8-1.6-2.5
Delay discounting water rate 12 sec2.53.78.40.71.7-0.4-2.92.62.81.21.82.70.80.40.5-2.9
Delay discounting water rate 18 sec0.91.22.60.61.2-0.2-1.61.11.60.81.21.50.60.40.5-1.6
Delay discounting water rate 24 sec1.31.73.90.31.0-0.5-2.01.61.80.71.91.70.50.00.3-2.0
Delay discounting water rate 6 sec0.50.82.0-1.0-0.3-1.4-0.70.40.6-1.00.50.5-1.2-1.0-1.4-0.8
Locomotor activity1.52.34.60.41.80.6-2.02.12.01.10.82.11.30.81.0-2.0
Locomotor testing distance1.72.85.50.42.30.6-2.21.92.21.11.12.31.41.01.0-2.2
Locomotor testing rearing1.72.66.7-0.21.7-0.5-2.62.32.40.60.52.40.60.20.1-2.6
Light reinforcement 10.81.53.8-0.20.9-0.4-2.01.91.80.50.81.70.3-0.00.2-1.9
Light reinforcement 21.41.93.81.61.40.9-1.02.01.31.7-0.71.41.61.61.4-1.0
Reaction time number correct0.81.12.4-1.5-1.4-1.3-0.0-0.2-0.3-1.30.2-0.5-1.5-1.6-1.4-0.0
Reaction time mean minus median0.00.10.4-0.50.2-0.1-0.1-0.3-0.0-0.2-0.60.0-0.0-0.10.0-0.1
Reaction time mean minus median AUC0.20.31.0-0.3-0.10.10.7-0.7-0.7-0.2-1.0-0.60.00.10.10.7
Reaction time num false alarms0.40.61.1-1.0-0.5-0.10.8-1.0-0.9-1.10.7-0.8-0.8-0.7-0.70.7
Reaction time num false alarms AUC0.50.61.3-1.1-0.7-0.50.6-0.8-0.7-1.10.7-0.7-0.9-0.8-0.90.5
Reaction time trials correct on left0.81.12.4-1.5-1.4-1.3-0.0-0.2-0.3-1.30.2-0.5-1.5-1.6-1.4-0.0
Reaction time trials on left0.71.02.2-1.4-1.3-1.2-0.1-0.2-0.2-1.20.3-0.4-1.4-1.5-1.3-0.1
Reaction time mean0.81.13.21.20.71.80.7-0.3-0.51.20.1-0.41.51.31.70.8
Reaction time mean AUC1.11.43.91.40.62.00.8-0.2-0.61.4-0.3-0.41.71.51.90.9
Median of all reaction times1.01.33.61.40.71.90.7-0.1-0.41.30.5-0.31.71.41.80.7
Reaction time omissions0.50.72.4-0.10.40.4-1.01.00.80.71.50.70.80.10.9-1.0
Reaction time false alarm rate0.30.40.9-0.4-0.20.20.9-0.9-0.9-0.60.2-0.8-0.3-0.1-0.20.9
Reaction time premature initiation rate0.81.12.01.41.40.2-0.90.91.21.2-0.61.21.01.20.7-0.9
Reaction time premature initiations0.30.51.20.30.5-0.7-1.00.91.10.3-0.61.0-0.00.1-0.2-1.0
Std. dev. reaction times0.20.31.10.40.61.00.3-0.3-0.20.6-0.2-0.10.90.71.00.3
Reaction time trials completed0.71.02.2-1.4-1.3-1.2-0.1-0.2-0.2-1.20.3-0.4-1.4-1.5-1.3-0.1
Reaction time trials AUC0.60.92.1-1.4-1.2-1.1-0.2-0.1-0.1-1.10.4-0.3-1.3-1.4-1.2-0.2
Social response proportion0.60.61.2-0.5-0.9-0.50.9-0.9-0.9-0.70.8-1.1-0.7-0.8-0.40.8
Social responses1.41.84.2-1.0-1.2-1.11.4-2.0-1.5-1.50.4-1.7-1.4-1.3-1.11.3
Social time3.54.511.4-2.3-1.9-3.40.6-1.6-0.9-2.8-1.2-1.2-2.9-2.6-3.00.4
Conditioned locomotion2.63.15.1-1.6-2.3-1.81.3-1.5-1.5-2.0-2.0-1.6-2.2-1.8-2.01.2
Cocaine response after cond. corrected0.30.30.6-0.6-0.4-0.00.5-0.5-0.6-0.7-0.8-0.6-0.5-0.4-0.50.5
Cocaine response after cond. not corrected0.80.81.3-1.1-1.1-0.40.7-0.7-0.9-1.1-1.0-0.9-1.0-0.9-1.00.7
Cocaine response before conditioning0.40.51.1-1.1-0.7-0.9-0.30.10.0-0.8-0.2-0.0-0.9-1.0-1.0-0.3
Saline control response0.10.20.5-0.4-0.1-0.6-0.4-0.00.3-0.40.50.1-0.4-0.7-0.5-0.5
Condit. Reinf. active minus inactive responses0.40.51.11.01.00.80.20.30.10.6-1.10.30.81.10.60.2
Condit. Reinf. active-inactive response ratio1.51.63.21.51.81.4-0.61.20.91.40.21.11.71.71.4-0.6
Condit. Reinf. active responses0.10.22.00.30.50.20.20.1-0.0-0.1-1.40.10.10.4-0.00.1
Condit. Reinf. inactive responses0.60.82.0-1.1-0.6-1.10.0-0.3-0.1-1.2-1.4-0.2-1.2-1.0-1.3-0.0
Condit. Reinf. lever presses0.50.71.61.11.20.8-0.40.80.70.8-0.90.80.81.10.8-0.4
Condit. Reinf. lever reinforcers received0.10.21.60.20.50.10.20.0-0.0-0.2-1.30.10.00.3-0.10.1
Pavlov. Cond. lever latency2.12.96.2-1.8-2.5-1.21.5-1.7-1.9-1.70.9-2.1-1.6-2.0-1.31.4
Pavlov. Cond. magazine entry latency1.31.53.61.21.90.6-1.21.31.51.0-0.61.61.01.40.6-1.2
Pavlov. Cond. change in total contacts1.82.66.11.42.51.3-1.61.61.91.40.32.01.51.61.2-1.6
Pavlov. Cond. index score3.14.08.61.72.91.1-2.12.22.51.7-0.52.71.72.01.3-2.1
Pavlov. Cond. latency score3.44.39.01.93.01.3-2.12.32.61.9-0.62.71.82.11.5-2.1
Pavlov. Cond. lever contacts1.92.75.81.42.41.0-1.71.82.01.5-0.42.11.41.71.2-1.7
Pavlov. Cond. magazine entry number0.50.61.9-0.6-1.4-0.30.8-0.7-1.1-0.50.4-1.1-0.4-0.8-0.30.8
Pavlov. Cond. intertrial magazine entries0.20.32.9-0.2-0.3-0.1-0.30.30.10.11.70.00.1-0.40.4-0.3
Pavlov. Cond. lever-magazine prob. diff.3.24.29.01.73.01.3-2.22.22.51.8-0.02.71.82.01.5-2.1
Pavlov. Cond. response bias0.81.13.31.11.80.7-0.90.91.20.8-0.71.40.81.30.5-0.9
Conditioned reinforcement - actives1.51.52.8-1.4-1.2-1.30.5-1.2-0.7-1.6-1.1-0.9-1.7-1.6-1.40.5
Conditioned reinforcement - inactives0.70.74.8-0.3-0.0-1.3-0.70.30.7-0.4-2.20.6-0.7-0.4-0.7-0.7
Conditioned locomotion0.00.00.2-0.1-0.1-0.2-0.1-0.20.1-0.1-0.5-0.0-0.1-0.30.1-0.1
Intermittent access intake day 1-15 change0.20.20.5-0.5-0.6-0.5-0.4-0.10.2-0.4-0.10.1-0.6-0.7-0.5-0.4
Intermittent access intake escalation0.10.10.3-0.2-0.5-0.0-0.0-0.2-0.1-0.2-0.5-0.1-0.4-0.4-0.20.0
Intermittent access intake escalation 20.30.30.8-0.5-0.2-0.5-0.7-0.10.5-0.30.90.4-0.5-0.6-0.4-0.7
Intermitt. access day 1 inactive lever presses0.50.62.40.50.7-0.1-0.70.90.90.5-1.50.90.30.50.2-0.7
Intermitt. access day 15 inactive lever presses0.80.92.40.40.6-0.1-1.41.51.40.7-0.51.40.40.30.4-1.4
Intermitt. access escalation Index0.20.10.40.40.40.50.0-0.00.00.50.40.00.60.50.70.1
Intermittent access day 1 total infusions0.50.61.31.00.80.8-0.20.50.41.0-0.70.41.00.91.1-0.2
Intermittent access day 15 total infusions0.40.41.11.00.30.80.10.10.10.9-1.00.10.70.71.00.1
Intermittent access terminal intake (last 3 days)0.40.41.20.90.30.70.2-0.1-0.00.7-1.10.00.70.70.90.2
Intermittent access total infusions0.50.61.61.10.61.00.3-0.1-0.10.9-0.7-0.01.01.01.30.4
Intermittent access day 1 locomotion0.90.92.11.50.91.00.20.10.11.3-0.70.21.31.41.40.3
Intermittent access day 15 total locomotion0.90.91.91.31.41.0-0.70.51.01.10.11.01.01.11.1-0.7
Intermittent access total locomotion1.31.43.41.81.21.80.4-0.20.01.4-0.60.11.51.61.70.5
Intermittent access standard deviation2.52.65.6-0.5-2.0-0.12.4-2.0-2.4-1.0-1.1-2.4-0.9-0.7-0.52.3
Cocaine induced anxiety0.50.61.61.00.90.3-0.40.60.60.9-1.30.60.80.90.7-0.4
Post-drug Anxiety0.20.20.50.60.70.4-0.20.50.30.6-0.20.30.70.60.5-0.2
Baseline Anxiety0.50.54.0-0.7-0.4-0.10.3-0.5-0.4-0.72.0-0.5-0.4-0.7-0.40.2
Lifetime Intake0.20.20.50.4-0.10.40.7-0.6-0.60.1-0.6-0.60.20.30.40.7
Incentive Sensitization - Responses0.40.41.10.20.50.0-1.10.61.00.40.50.90.20.00.4-1.0
Incentive Sensitization - Breakpoint0.40.51.20.20.60.1-1.10.71.10.40.60.90.20.00.4-1.1
Progressive ratio test 1 active lever presses1.01.12.31.50.91.1-0.00.70.31.3-1.20.51.31.41.40.1
Progressive ratio test 1 breakpoint0.70.71.61.30.70.8-0.10.60.31.1-1.10.41.01.21.2-0.0
Progressive ratio test 1 inactive lever presses0.20.31.90.20.3-0.5-0.40.30.50.1-1.40.5-0.10.2-0.0-0.5
Progressive ratio test 2 active lever presses0.30.30.70.50.60.1-0.70.50.80.5-0.20.80.40.30.6-0.7
Progressive ratio test 2 breakpoint0.60.71.40.70.90.3-1.10.91.20.80.01.10.60.60.8-1.0
Progressive ratio test 2 inactive lever presses0.20.21.40.20.5-0.1-0.50.30.60.2-1.20.60.00.20.2-0.5
Total sessions with >9 infusions0.30.40.9-0.8-1.0-0.30.4-0.3-0.6-0.80.0-0.6-0.7-0.8-0.60.4
Short access day 1 total inactive lever presses0.70.82.2-1.2-0.7-1.5-0.2-0.30.1-1.2-0.10.0-1.3-1.2-1.3-0.3
Short access day 10 total inactive lever presses0.50.51.2-0.40.2-0.8-1.11.01.0-0.20.40.9-0.4-0.3-0.6-1.1
Short access day 1 total infusions0.80.81.3-1.0-1.1-0.60.8-0.9-0.9-1.10.2-0.9-1.1-1.0-1.00.7
Short access day 10 total infusions0.20.20.40.30.00.50.6-0.4-0.50.3-0.4-0.50.50.40.60.6
Short access total infusions0.40.41.0-0.2-0.50.01.0-1.0-1.0-0.4-0.6-0.9-0.2-0.2-0.11.0
Short access day 1 locomotion0.70.71.80.1-1.00.41.3-0.9-1.2-0.3-0.8-1.2-0.5-0.1-0.21.4
Short access day 10 total locomotion1.21.33.60.1-0.70.71.9-1.6-1.7-0.2-1.0-1.70.00.20.31.9
Short access total locomotion1.61.63.1-0.5-1.3-0.21.7-1.6-1.7-0.8-1.5-1.7-0.8-0.5-0.51.7
Compulsive drug intake0.30.30.5-0.30.7-0.6-0.60.00.6-0.50.50.6-0.4-0.3-0.7-0.7
One hour access (0.3 mA shock)0.30.41.0-0.3-0.3-0.80.2-1.0-0.1-0.7-0.6-0.3-0.9-0.7-0.70.1
One hour access (shock baseline)0.20.30.80.80.20.4-0.0-0.00.20.8-0.80.10.60.50.90.0
Number of responses in last shaping day0.10.11.0-0.10.0-0.0-0.50.10.40.11.00.3-0.1-0.20.1-0.5
Context. condit. distance diff. score0.80.93.41.01.80.2-0.80.41.00.71.21.10.91.00.6-0.9
Locomotion velocity, session 11.71.83.9-1.60.8-1.2-1.90.81.5-0.91.71.4-0.7-1.1-1.0-2.0
Locomotion distance, session 11.72.35.30.12.0-0.2-2.31.92.30.5-0.32.30.60.5-0.0-2.3
Locomotion velocity, session 23.54.111.8-0.91.5-0.6-3.42.83.10.31.12.90.2-0.50.0-3.4
Locomotion distance, session 20.71.02.3-0.60.5-0.8-1.51.31.4-0.2-1.21.3-0.2-0.4-0.6-1.5
Locomotion velocity, session 31.41.63.2-1.50.9-1.6-1.60.61.4-1.10.41.3-0.9-1.0-1.4-1.8
Locomotion distance, session 31.82.04.7-2.2-1.0-1.90.2-0.9-0.5-2.0-0.8-0.6-1.8-1.8-2.00.1
Stereotopy head waving bouts, day 30.60.71.40.70.60.9-0.81.20.90.9-1.10.90.70.70.9-0.7
Stereotopy head waving duration, day 31.01.22.50.51.20.5-1.61.41.60.90.41.60.80.60.7-1.5
Locomotion velocity, session 70.60.71.5-0.20.9-1.2-1.10.21.1-0.40.61.0-0.4-0.4-0.7-1.2
Locomotion distance, session 70.30.40.9-0.10.6-1.0-0.70.10.7-0.30.60.7-0.3-0.2-0.6-0.8
Stereotopy head waving bouts, day 70.10.11.0-0.4-0.30.6-0.00.2-0.0-0.1-1.00.0-0.1-0.1-0.00.0
Stereotopy head waving duration, day 70.20.30.7-0.1-0.30.80.7-0.4-0.6-0.1-0.8-0.50.10.20.10.7
Locomotion velocity, session 80.70.92.20.31.5-0.5-1.30.91.40.3-0.21.40.40.4-0.1-1.4
Locomotion distance, session 80.91.44.10.72.0-0.2-1.51.11.70.5-0.31.80.60.80.0-1.6
Degree of sensitization distance1.61.62.41.51.40.6-1.21.21.41.41.51.41.11.11.2-1.2
Degree of sensitization stereotypy0.91.01.8-0.8-1.30.31.2-0.9-1.3-0.8-1.3-1.2-0.7-0.5-0.61.3
Condit. Reinf. active minus inactive responses1.92.14.21.72.00.7-1.41.41.71.5-0.21.81.41.61.2-1.3
Condit. Reinf. active-inactive response ratio0.91.02.01.41.01.2-0.30.70.61.3-0.00.71.21.31.3-0.3
Condit. Reinf. active responses2.22.75.51.52.30.4-1.91.82.21.4-0.32.31.31.51.0-1.9
Condit. Reinf. inactive responses1.21.43.00.71.60.1-1.61.31.70.9-0.51.70.80.80.5-1.6
Incentive salience index mean1.82.24.81.02.1-0.3-2.01.62.21.0-0.22.20.90.90.5-2.0
Condit. Reinf. lever presses2.33.17.60.62.0-0.7-2.72.22.70.9-0.52.60.70.50.4-2.8
Time in familiar zone, hab. session 11.41.33.2-1.8-0.8-1.5-1.10.60.7-1.10.20.4-1.3-1.7-1.3-1.2
Time in novel zone, hab. session 10.70.71.40.90.31.21.1-0.8-0.90.60.5-0.70.81.00.71.1
Total zone transitions, hab. session 12.53.67.31.12.20.4-2.42.72.61.4-1.22.71.21.30.8-2.4
Total locomotion distance, hab. session 12.23.17.40.31.5-0.2-2.72.72.71.0-0.12.60.70.50.3-2.7
Locomotion velocity, hab. session 12.02.97.10.31.5-0.4-2.72.52.60.9-0.32.60.50.40.2-2.7
Time in familiar zone, hab. session 21.81.94.2-0.7-1.50.31.7-1.9-1.9-0.72.1-1.9-0.5-0.7-0.11.7
Time in novel zone, hab. session 20.50.52.30.20.7-0.4-0.80.90.90.1-1.50.90.10.3-0.3-0.8
Total zone transitions, hab. session 22.83.64.92.02.22.0-1.42.21.82.1-1.41.92.12.21.9-1.3
Total locomotion distance, hab. session 21.82.44.21.51.41.3-1.52.11.71.8-0.91.81.51.61.5-1.3
Locomotion velocity, hab. session 21.41.93.51.31.11.3-1.21.91.41.6-1.21.51.41.41.4-1.1
Novel to familiar place preference ratio0.30.33.00.1-0.4-0.20.10.2-0.10.1-1.7-0.1-0.20.0-0.20.2
Novelty place preference0.40.43.0-0.1-0.7-0.50.3-0.0-0.3-0.2-1.7-0.3-0.5-0.3-0.50.3
Time in novel zone, NPP test0.40.43.0-0.1-0.8-0.40.4-0.1-0.4-0.2-1.7-0.4-0.5-0.3-0.40.4
Total zone transitions, NPP test4.05.811.61.43.00.9-3.23.13.31.9-0.03.41.81.61.4-3.1
Total locomotion distance, NPP test3.34.68.61.32.41.0-2.72.82.91.90.92.91.71.51.5-2.7
Locomotion velocity, NPP test3.75.39.61.52.61.1-2.93.03.12.10.93.11.81.61.6-2.8
Pavlov. Cond. lever latency1.52.05.40.4-0.81.62.2-1.6-2.10.00.5-1.90.30.60.62.3
Pavlov. Cond. magazine entry latency1.01.22.9-0.80.0-1.7-1.40.81.2-0.7-1.11.0-1.0-1.0-1.3-1.4
Pavlov. Cond. change in total contacts1.41.53.30.61.1-0.6-1.81.51.80.6-1.31.70.30.30.1-1.8
Pavlov. Cond. index score1.72.25.9-0.70.7-1.8-2.31.62.1-0.4-0.51.9-0.6-0.9-1.0-2.4
Pavlov. Cond. latency score1.62.14.7-1.00.3-2.1-2.11.21.8-0.7-0.61.6-1.0-1.2-1.3-2.2
Pavlov. Cond. lever contacts2.02.46.7-0.21.1-1.5-2.51.92.40.1-0.12.2-0.1-0.5-0.5-2.6
Pavlov. Cond. magazine entry number1.21.53.40.6-0.41.31.8-1.4-1.70.41.3-1.50.70.71.01.8
Pavlov. Cond. intertrial magazine entries0.30.41.10.1-0.1-0.21.0-1.0-0.9-0.3-1.0-0.7-0.10.2-0.40.9
Pavlov. Cond. lever-magazine prob. diff.1.62.15.5-0.50.8-1.8-2.31.52.1-0.3-0.61.9-0.6-0.8-0.9-2.3
Pavlov. Cond. response bias2.22.77.3-0.01.3-1.2-2.72.22.60.3-0.42.40.0-0.2-0.4-2.7
Bone: apparent density0.81.33.20.9-0.90.91.7-0.7-1.40.4-1.6-1.20.20.80.51.8
Bone surface1.01.84.3-0.2-1.20.52.1-1.6-1.9-0.8-1.7-1.8-0.7-0.1-0.52.1
Bone volume0.61.02.70.3-0.90.51.6-0.9-1.4-0.2-1.3-1.3-0.30.3-0.01.6
Bone: connectivity density1.52.35.71.0-0.91.52.3-1.0-1.90.4-2.3-1.60.41.10.82.4
Bone: cortical apparent density1.01.33.2-1.8-1.4-0.70.5-1.1-0.9-1.40.5-1.0-1.2-1.5-1.20.5
Bone: cortical area0.71.03.2-0.8-0.7-1.6-0.90.80.7-0.6-1.80.6-1.1-1.0-1.1-0.9
Bone: cortical porosity0.40.42.01.40.10.30.30.3-0.01.0-0.20.00.71.00.80.3
Bone: cortical porosity0.20.21.21.10.1-0.40.10.20.10.7-0.20.10.30.60.30.1
Bone: cortical thickness0.71.23.8-0.7-0.9-1.6-1.11.20.9-0.3-2.00.7-0.9-1.0-0.9-1.1
Bone: cortical thickness0.20.30.80.8-0.10.50.5-0.1-0.30.6-0.9-0.20.40.70.60.5
Bone: cortical tissue density0.81.12.9-1.7-1.2-0.60.4-1.0-0.8-1.30.7-0.9-1.1-1.4-1.00.4
Bone: elastic displacement0.20.20.3-0.3-0.6-0.30.4-0.4-0.5-0.30.5-0.5-0.3-0.4-0.30.4
Bone: elastic work0.10.10.50.7-0.20.20.20.3-0.10.6-0.3-0.10.40.40.60.2
Bone: endosteal estimation0.10.31.10.10.20.10.8-1.1-0.7-0.40.3-0.7-0.10.0-0.20.7
Bone: endosteal perimeter0.00.10.3-0.00.5-0.2-0.1-0.10.2-0.4-0.60.2-0.20.0-0.4-0.1
Bone: final force0.20.41.80.40.4-0.4-0.60.60.70.2-1.30.7-0.00.3-0.2-0.6
Bone: final moment0.30.52.30.10.3-0.9-0.80.60.8-0.1-1.50.7-0.4-0.1-0.6-0.8
Bone: marrow area0.20.31.3-0.00.1-0.10.9-1.1-0.8-0.60.1-0.7-0.3-0.1-0.30.8
Bone: maximum diameter0.40.82.2-0.60.1-1.4-0.90.40.8-0.7-1.50.7-0.8-0.7-1.1-0.9
Bone: maximum force0.20.31.40.90.30.30.30.0-0.00.5-1.20.00.30.70.30.3
Bone: maximum moment0.10.22.20.60.0-0.20.2-0.0-0.00.2-1.50.0-0.00.3-0.10.2
Bone: minimum diameter0.10.31.5-0.2-0.2-0.7-0.40.50.4-0.2-1.20.4-0.5-0.3-0.4-0.4
Bone: periosteal estimation0.20.31.0-0.4-0.1-1.0-0.30.00.3-0.6-0.90.2-0.7-0.6-0.8-0.4
Bone: periosteal perimeter0.30.51.7-0.00.3-0.7-0.90.90.9-0.0-1.30.9-0.2-0.1-0.4-0.9
Bone: post-yield work0.50.62.11.31.40.80.0-0.00.30.8-0.20.51.01.30.6-0.0
Bone: stiffness0.10.20.70.3-0.40.20.6-0.3-0.40.0-0.8-0.4-0.10.20.00.6
Bone: tissue strength0.30.32.20.3-0.6-0.60.5-0.2-0.4-0.1-1.5-0.5-0.4-0.1-0.30.5
Bone: trabecular number0.81.23.5-0.1-1.30.11.5-0.9-1.4-0.5-1.9-1.3-0.6-0.1-0.41.6
Bone: trabecular spacing0.81.13.0-0.80.7-0.7-1.70.91.4-0.21.41.2-0.1-0.7-0.3-1.7
Bone: trabecular thickness1.11.33.80.7-1.00.71.9-1.0-1.60.0-1.3-1.5-0.10.50.22.0
Bone: trabecular tissue density0.70.92.7-1.0-0.8-1.7-0.1-0.4-0.1-1.1-1.0-0.2-1.3-1.1-1.5-0.2
Breakpoint value in progressive ratio session0.10.10.9-0.20.20.3-0.30.20.3-0.4-1.00.2-0.4-0.2-0.2-0.2
Distance traveled before self-admin0.30.30.7-0.6-0.0-0.7-0.60.20.5-0.30.80.4-0.4-0.6-0.5-0.7
Distance traveled after self-admin2.02.34.30.81.70.5-2.02.02.11.30.02.11.21.01.0-2.0
Delta time in closed arm before/after self-admin0.80.73.80.70.80.8-0.30.30.40.92.00.41.00.81.1-0.3
Delta time in open arm before/after self-admin0.70.76.30.4-0.20.20.8-0.5-0.6-0.1-2.5-0.5-0.20.3-0.20.8
Diff in mean of infusions in LGA sessions0.50.64.30.20.3-0.4-0.80.70.80.0-2.10.7-0.2-0.2-0.1-0.8
Extinction: sum of active levers before priming0.20.22.10.10.50.2-0.10.30.20.0-1.40.30.10.30.2-0.1
Active lever presses in extinction session 60.50.51.3-0.60.5-0.7-1.00.30.9-0.41.10.8-0.4-0.5-0.3-1.1
Delta distance traveled before/after self-admin4.04.25.92.22.41.6-1.72.42.12.4-0.72.22.32.22.1-1.6
Delta ambulatory time before/after self-admin2.62.84.51.91.71.1-1.32.11.62.1-1.11.71.91.91.7-1.2
Time in closed arm before self-admin1.11.28.41.1-0.20.81.1-0.5-0.80.5-2.9-0.70.50.80.31.2
Time in closed arm after self-admin0.80.91.51.2-0.21.10.9-0.2-0.81.20.3-0.71.21.01.21.0
Time in open arm before self-admin1.92.05.0-0.90.5-1.0-2.21.61.9-0.12.11.6-0.2-0.9-0.3-2.2
Time in open arm after self-admin0.40.40.9-0.00.5-0.2-0.90.81.0-0.1-0.90.9-0.2-0.1-0.1-1.0
Sum of active levers in priming session hrs 5-61.71.73.8-1.8-0.9-1.70.1-0.9-0.3-1.90.2-0.4-2.0-1.7-1.90.0
Time to tail flick, vehicle, before self-admin0.60.61.5-0.7-0.9-0.90.6-0.8-0.7-0.81.2-0.7-0.8-0.7-0.70.5
Time to tail flick, vehicle, after self-admin1.41.52.7-1.3-0.9-0.71.5-1.6-1.6-1.4-0.9-1.4-1.0-0.7-1.11.4
Time to tail flick, test, before self-admin4.34.26.1-2.4-2.4-1.21.3-2.3-1.8-2.52.0-2.0-2.4-2.5-2.11.3
Time to tail flick, test, after self-admin1.41.43.0-1.6-1.1-1.50.7-0.7-0.9-1.6-1.1-0.8-1.4-1.1-1.70.6
Delta time to tail flick, vehicle, before/after SA0.60.61.8-1.0-0.8-0.40.7-0.5-0.8-0.9-1.3-0.7-0.7-0.6-0.80.7
Delta time to tail flick, test, before/after SA1.00.92.50.91.20.6-0.21.10.50.9-1.60.81.21.40.8-0.2
Ambulatory time before self-admin0.60.72.9-1.1-0.4-0.9-0.5-0.30.2-0.81.70.0-0.8-1.1-0.7-0.5
Ambulatory time after self-admin1.82.03.90.61.60.3-1.91.82.01.2-0.02.01.10.80.9-1.9
Total heroin consumption0.10.10.4-0.2-0.20.6-0.10.60.00.00.5-0.00.1-0.10.4-0.0
Area under the delay curve4.44.710.2-2.1-1.9-1.71.9-3.2-2.1-2.51.9-2.3-2.3-2.1-2.21.7
Delay disc. indifference point, 0s delay0.60.71.9-0.1-0.50.21.2-1.3-1.1-0.4-1.4-0.9-0.20.1-0.21.1
Delay disc. indifference point, 16s delay7.87.912.7-2.8-3.0-1.92.4-3.6-2.9-3.22.7-3.1-2.9-2.9-2.62.2
Delay disc. indifference point, 2s delay1.11.23.6-1.2-0.6-0.70.8-1.8-1.0-1.21.9-1.0-0.8-0.9-0.90.7
Delay disc. indifference point, 24s delay0.60.65.0-0.5-0.30.10.5-0.7-0.6-0.62.2-0.6-0.4-0.4-0.20.5
Delay disc. indifference point, 4s delay3.03.17.0-2.0-1.4-2.60.6-2.0-0.9-2.20.6-1.0-2.3-2.1-2.40.4
Delay disc. indifference point, 8s delay2.93.05.8-1.7-1.5-1.51.4-2.4-1.6-2.21.3-1.7-2.0-1.8-1.81.2
Delay discount exponential model param4.54.79.82.21.81.9-1.73.12.02.6-2.12.12.32.12.3-1.6
Delay discount hyperbolic model param3.94.18.92.01.61.8-1.63.01.82.4-1.92.02.22.02.2-1.4
Fecal boli incidents, locomotor time 11.61.73.6-1.9-0.8-1.7-0.1-0.8-0.2-1.81.3-0.4-1.7-1.8-1.7-0.3
Change in fecal boli incidents, locomotor task0.10.10.2-0.0-0.4-0.40.0-0.3-0.0-0.00.1-0.2-0.3-0.4-0.20.0
Time >=10cm from walls, locomotor time 10.20.20.7-0.10.5-0.3-0.80.10.70.10.80.50.1-0.20.1-0.8
Bouts of movement, locomotor time 10.91.02.71.10.71.40.9-0.2-0.60.7-1.7-0.40.91.31.01.0
Total resting periods, locomotor time 10.91.02.71.20.91.40.40.3-0.11.0-1.60.11.11.41.10.5
Rest time, locomotor task time 10.60.71.3-0.3-0.6-0.51.1-1.1-1.0-0.6-1.2-0.9-0.6-0.1-0.51.1
Distance moved, locomotor task time 10.20.21.10.10.50.2-0.40.40.40.21.00.40.30.10.1-0.4
Vertical activity count, locomotor time 10.20.21.5-0.30.2-0.5-0.0-0.6-0.0-0.41.2-0.1-0.2-0.4-0.4-0.1
Time >=10cm from walls, locomotor time 20.80.92.20.11.2-0.5-1.40.71.40.31.01.30.30.10.2-1.5
Bouts of movement, locomotor time 20.10.10.50.40.20.6-0.20.70.30.20.20.30.20.20.5-0.2
Total resting periods, locomotor time 20.10.10.50.30.00.70.20.3-0.10.20.3-0.10.20.20.50.2
Rest time, locomotor task time 20.50.51.60.2-0.20.71.2-0.8-1.1-0.1-0.5-0.90.10.40.21.2
Distance moved, locomotor task time 20.60.71.50.70.80.1-0.81.21.00.9-0.51.00.70.80.4-0.8
Vertical activity count, locomotor time 20.20.20.8-0.30.2-0.9-0.3-0.20.3-0.40.20.2-0.4-0.4-0.7-0.4
Weight adjusted by age0.20.31.4-0.3-0.1-0.0-0.81.20.60.20.10.50.1-0.30.2-0.7
Seeking ratio, delayed vs. immediate footshock0.70.93.1-0.0-0.50.31.4-1.8-1.3-0.50.4-1.3-0.2-0.1-0.31.4
Locomotion in novel chamber0.40.51.2-0.7-0.6-0.20.6-1.1-0.7-0.80.9-0.8-0.7-0.7-0.40.6
Locomotion in novel chamber post-restriction2.83.46.1-2.5-2.0-2.20.6-1.4-1.0-2.4-0.4-1.2-2.5-2.4-2.40.5
Progressive ratio0.60.75.7-0.80.4-0.6-0.1-0.8-0.0-0.82.4-0.1-0.5-0.6-0.6-0.2
Food seeking constrained by brief footshock0.30.41.10.71.10.8-0.40.20.50.70.50.50.80.70.7-0.4
Seeking ratio, punishment vs. effort0.60.73.71.00.20.6-0.20.80.41.0-1.90.40.60.80.8-0.1
Run reversals in cocaine runway, females0.70.71.5-0.50.3-1.1-1.20.91.0-0.21.11.0-0.3-0.4-0.5-1.2
Run reversals in cocaine runway, males0.10.10.4-0.5-0.5-0.1-0.0-0.1-0.1-0.4-0.6-0.1-0.5-0.4-0.40.0
Latency to leave start box in cocaine runway0.50.61.60.10.4-0.2-1.01.31.00.2-1.21.0-0.00.1-0.3-1.0
Latency to leave start box in cocaine runway, F0.40.44.30.1-0.20.10.30.3-0.2-0.2-2.1-0.1-0.30.1-0.50.4
Latency to leave start box in cocaine runway, M2.12.15.20.31.1-0.3-2.32.12.20.90.22.10.60.20.5-2.2
Cd content in liver0.40.41.2-0.1-0.2-0.70.8-1.1-0.7-0.7-0.3-0.7-0.6-0.2-0.70.8
Co content in liver0.50.61.90.81.40.8-0.50.20.70.80.30.71.00.80.9-0.6
Cu content in liver1.01.22.6-1.6-0.9-1.20.0-0.8-0.3-1.31.6-0.6-1.3-1.6-1.1-0.1
Fe content in liver0.50.63.6-0.7-0.4-0.60.4-0.9-0.5-0.81.9-0.6-0.6-0.8-0.50.3
K content in liver1.41.43.11.30.21.61.0-0.6-0.81.21.4-0.71.41.21.71.1
Mg content in liver1.31.42.3-1.3-1.5-0.71.0-1.5-1.3-1.01.1-1.5-0.9-1.3-0.71.0
Mn content in liver1.11.33.20.80.31.7-0.51.00.41.41.70.51.40.81.8-0.4
Na content in liver0.20.20.8-0.4-0.8-0.5-0.20.20.0-0.20.9-0.1-0.4-0.6-0.2-0.2
Rb content in liver4.05.08.8-2.2-2.4-1.62.2-3.0-2.5-2.5-0.5-2.7-2.2-2.2-2.12.1
Se content in liver0.10.10.5-0.20.2-0.1-0.60.30.5-0.00.70.40.0-0.2-0.1-0.6
Sr content in liver0.50.53.50.00.4-0.0-0.60.90.6-0.0-1.90.7-0.10.2-0.4-0.5
Zn content in liver3.63.97.5-1.7-2.2-2.71.5-2.4-1.7-2.10.3-2.0-2.3-2.2-2.11.3