Hub : Genes

Prr14l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000048891	0.15	0.07	6.4e-11	0.1	0.1	0.1	0.05	1.3e-11	8.6e-11	9.5e-11	1.1e-06
2	Adipose	intron excision ratio	chr14:77870041:77879708	0.05	0.03	1.5e-03	0.01	0.01	0.02	0.01	5.5e-02	8.9e-03	5.7e-03	1.2e-02
3	Adipose	mRNA stability	ENSRNOG00000048891	0.04	0.03	2.6e-03	0.03	0.03	0.03	0.03	8.3e-04	6.2e-04	3.7e-04	6.6e-04
4	Brain	gene expression	ENSRNOG00000048891	0.15	0.07	6.7e-09	0.1	0.08	0.1	0.1	1.1e-09	1.2e-07	4.0e-09	3.3e-09
5	NAcc	gene expression	ENSRNOG00000048891	0.14	0.08	3.5e-05	0.03	0.05	0.06	0.06	3.4e-03	1.2e-04	2.8e-05	4.9e-05
6	PL	intron excision ratio	chr14:77872156:77879708	0.06	0.04	2.6e-03	0.02	0.03	0.01	0.03	1.3e-02	1.6e-03	4.1e-02	2.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	3.1	10.0	19.9	0.0	4.5	-2.6	-2.5	-4.1	-3.1
BMI without tail	1.8	3.8	9.7	1.1	3.1	-0.9	-1.1	-2.9	-1.3
Body weight	2.8	11.9	27.7	-0.0	5.3	-2.3	-3.1	-4.8	-2.4
Epididymis fat weight	0.9	2.0	5.6	1.0	2.4	-0.6	-0.4	-2.0	-1.1
Glucose	3.9	5.9	12.4	-3.4	1.3	-2.2	-3.5	-1.9	-1.2
Heart weight	0.1	0.2	0.3	0.5	0.4	0.3	0.4	-0.2	0.4
Left kidney weight	1.2	3.3	7.8	2.7	2.8	1.1	0.8	-1.7	0.6
Right kidney weight	0.7	1.9	5.4	1.8	2.3	0.0	0.6	-1.5	-0.5
Tail length	0.2	0.7	1.1	0.8	1.0	0.9	-0.3	-1.0	1.1
Length with tail	0.4	1.5	4.1	0.6	2.0	0.4	-0.9	-1.8	0.6
Length without tail	0.5	1.2	3.3	-0.2	1.8	-0.5	-1.1	-1.4	-0.3
Liver weight, left	1.1	1.8	3.8	1.6	-0.8	1.4	1.9	0.9	1.0
Liver weight, right	1.3	2.1	7.1	2.7	0.4	1.3	1.9	-0.1	0.6
Parametrial fat weight	1.2	2.3	5.0	-2.2	0.1	-1.8	-1.7	-0.4	-1.5
Retroperitoneal fat weight	0.4	1.4	2.9	0.3	1.7	-1.0	-0.5	-1.5	-1.4
Intraocular pressure	0.1	0.2	0.6	0.6	0.8	0.2	-0.0	-0.4	0.1
Extensor digitorum longus weight	1.6	6.6	13.5	-0.9	3.2	-1.8	-3.1	-3.7	-1.4
Soleus weight	0.7	2.0	5.5	0.6	2.0	0.1	-1.3	-2.3	0.5
Tibialis anterior weight	0.9	3.0	6.3	-0.7	2.1	-1.2	-2.2	-2.5	-0.8
Tibia length	0.2	0.6	2.0	1.4	0.8	0.4	0.5	-0.6	-0.0
Number of licking bursts	0.3	0.3	0.6	0.8	0.7	0.5	0.1	-0.6	0.5
Food consumed during 24 hour testing period	0.4	0.4	1.7	-0.1	-0.5	0.8	-0.0	0.3	1.3
Times rat made contact with spout	0.8	0.9	1.6	-0.2	-1.1	1.0	0.5	1.3	1.3
Mean time between licks in bursts	1.5	2.1	3.5	0.1	-1.9	1.4	1.0	1.7	1.9
Mean num. licks in bursts	0.8	1.0	2.5	-0.9	-1.6	0.2	0.3	1.5	0.4
Std. dev. time between licks in bursts	1.7	2.0	3.1	1.3	-1.0	1.6	1.8	1.4	1.4
Water consumed over 24 hours	2.3	2.7	4.7	0.3	-2.0	1.8	1.1	1.7	2.2
Indifference point 0 sec	0.1	0.1	0.2	0.4	-0.3	0.3	0.4	-0.1	0.2
Indifference point AUC	0.1	0.1	0.3	-0.3	-0.2	0.4	-0.0	0.3	0.6
Indifference point function ln k	0.1	0.2	0.5	-0.2	-0.7	0.2	0.2	0.6	0.3
Indifference point function log k	0.1	0.2	0.5	-0.2	-0.7	0.2	0.2	0.6	0.3
Delay discounting total patch changes 0 sec	0.0	0.0	0.1	0.3	-0.2	0.2	0.2	-0.2	0.2
Delay discounting total patch changes 12 sec	0.2	0.2	0.6	-0.0	0.4	-0.3	-0.4	-0.8	-0.5
Delay discounting total patch changes 18 sec	0.0	0.0	0.1	0.2	0.2	0.2	-0.0	-0.3	0.1
Delay discounting total patch changes 24 sec	0.8	1.0	2.6	1.6	-0.3	0.9	1.5	0.2	0.2
Delay discounting total patch changes 6 sec	0.1	0.1	0.5	-0.2	0.0	0.1	-0.4	-0.7	0.2
Delay discounting time to switch 0 sec	0.6	0.9	2.5	1.6	0.9	-0.1	0.8	-0.8	-0.8
Delay discounting water rate 0 sec	0.3	0.5	1.6	-0.5	-0.2	0.6	-0.9	-0.2	1.3
Delay discounting water rate 12 sec	0.3	0.5	1.2	0.0	-1.1	0.7	-0.1	0.5	0.9
Delay discounting water rate 18 sec	1.2	1.6	2.5	1.3	-1.3	1.6	1.1	0.7	1.5
Delay discounting water rate 24 sec	1.0	1.4	3.7	1.0	-1.0	1.6	0.4	0.2	1.9
Delay discounting water rate 6 sec	0.7	1.0	2.2	1.2	-0.3	1.5	0.2	0.1	1.5
Locomotor activity	0.3	0.6	1.7	0.3	-0.4	1.1	0.2	0.2	1.3
Locomotor testing distance	0.2	0.4	1.3	0.3	0.8	0.1	-0.5	-1.1	0.1
Locomotor testing rearing	0.9	1.4	3.1	-0.2	1.8	-0.2	-1.4	-1.8	-0.0
Light reinforcement 1	0.7	1.2	3.7	0.9	1.6	-0.2	-0.5	-1.9	-0.3
Light reinforcement 2	0.6	0.7	2.5	1.6	0.7	0.8	0.3	-0.8	0.4
Reaction time number correct	1.4	2.0	5.0	1.4	0.7	1.9	0.7	-0.3	2.2
Reaction time mean minus median	0.2	0.3	0.9	-0.4	-0.9	0.1	0.1	0.9	0.1
Reaction time mean minus median AUC	0.2	0.2	0.5	0.0	0.7	-0.4	-0.5	-0.5	-0.5
Reaction time num false alarms	1.9	2.6	5.0	-0.5	1.6	-1.9	-1.2	-1.6	-2.2
Reaction time num false alarms AUC	1.9	2.6	4.7	-0.1	1.9	-1.8	-1.0	-1.8	-2.2
Reaction time trials correct on left	1.4	2.0	5.0	1.4	0.7	1.9	0.7	-0.3	2.2
Reaction time trials on left	1.4	1.9	5.0	1.4	0.6	1.9	0.7	-0.3	2.2
Reaction time mean	0.2	0.3	0.7	-0.4	-0.9	-0.3	0.1	0.8	-0.4
Reaction time mean AUC	0.2	0.3	0.8	-0.4	-0.9	-0.2	0.1	0.8	-0.4
Median of all reaction times	0.2	0.3	0.5	-0.4	-0.7	-0.3	0.1	0.7	-0.5
Reaction time omissions	0.0	0.0	0.1	-0.3	-0.2	-0.2	-0.1	0.3	-0.2
Reaction time false alarm rate	2.5	3.6	9.1	-0.7	1.4	-2.5	-1.3	-1.5	-3.0
Reaction time premature initiation rate	1.9	2.5	5.6	2.4	-0.3	1.7	2.3	0.9	0.9
Reaction time premature initiations	2.4	3.5	7.2	2.7	0.2	2.3	2.2	0.5	1.9
Std. dev. reaction times	0.1	0.1	0.4	-0.1	-0.5	-0.1	0.1	0.6	-0.2
Reaction time trials completed	1.4	1.9	5.0	1.4	0.6	1.9	0.7	-0.3	2.2
Reaction time trials AUC	1.2	1.8	5.0	1.2	0.6	1.8	0.6	-0.3	2.2
Social response proportion	1.2	1.3	2.3	-0.1	-1.5	1.0	0.9	1.3	1.5
Social responses	0.4	0.5	1.9	0.2	-0.0	0.9	0.3	0.1	1.4
Social time	0.8	1.0	2.3	-0.3	-1.5	0.7	0.8	1.2	1.0
Conditioned locomotion	0.3	0.4	1.3	0.1	0.5	-0.8	0.2	-0.1	-1.2
Cocaine response after cond. corrected	0.4	0.4	1.1	-1.1	-0.8	-0.5	-0.4	0.3	-0.4
Cocaine response after cond. not corrected	0.5	0.5	1.5	-1.2	-0.4	-0.7	-0.8	-0.0	-0.6
Cocaine response before conditioning	0.1	0.2	0.5	0.1	0.7	0.1	-0.5	-0.4	0.2
Saline control response	0.1	0.2	0.5	-0.3	-0.7	0.2	0.2	0.6	0.4
Condit. Reinf. active minus inactive responses	0.5	0.6	1.0	0.9	-0.2	1.0	0.7	0.3	1.0
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.4	-0.5	-0.1	-0.6	-0.3	0.1	-0.6
Condit. Reinf. active responses	0.5	0.6	1.0	0.5	-0.7	0.9	0.8	0.8	1.0
Condit. Reinf. inactive responses	0.9	1.1	1.7	0.9	-0.7	1.2	1.1	0.9	1.3
Condit. Reinf. lever presses	0.1	0.1	0.2	0.5	0.4	0.2	0.3	-0.4	0.0
Condit. Reinf. lever reinforcers received	0.1	0.1	0.3	0.3	-0.3	0.4	0.5	0.3	0.5
Pavlov. Cond. lever latency	0.5	0.7	1.3	-0.3	1.1	-0.8	-1.0	-1.1	-0.6
Pavlov. Cond. magazine entry latency	0.6	0.7	1.9	0.6	1.3	-0.1	-0.1	-1.4	-0.3
Pavlov. Cond. change in total contacts	0.1	0.1	0.3	0.4	-0.2	0.4	0.6	0.0	0.2
Pavlov. Cond. index score	0.2	0.2	0.5	0.6	-0.1	0.5	0.7	0.2	0.3
Pavlov. Cond. latency score	0.2	0.3	0.6	0.7	-0.1	0.6	0.8	0.3	0.4
Pavlov. Cond. lever contacts	0.6	0.9	1.9	0.1	-1.3	0.7	1.0	1.4	0.6
Pavlov. Cond. magazine entry number	0.5	0.6	1.3	-1.0	-1.2	-0.4	-0.3	1.0	-0.2
Pavlov. Cond. intertrial magazine entries	0.2	0.3	0.8	-0.9	-0.7	-0.3	-0.5	0.5	-0.2
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.7	0.8	-0.1	0.7	0.8	0.2	0.4
Pavlov. Cond. response bias	0.1	0.2	0.4	0.4	-0.2	0.5	0.6	0.3	0.2
Conditioned reinforcement - actives	3.6	3.6	7.2	-0.3	2.7	-1.5	-1.5	-2.5	-1.8
Conditioned reinforcement - inactives	3.1	3.5	6.4	-0.8	2.5	-1.4	-2.1	-2.4	-1.5
Conditioned locomotion	0.9	1.0	1.9	-0.1	1.4	-0.7	-1.2	-1.4	-0.7
Intermittent access intake day 1-15 change	1.3	1.3	4.2	-1.4	-2.1	-0.5	-0.6	0.8	-0.5
Intermittent access intake escalation	1.8	1.8	6.8	-1.5	-2.6	-0.4	-0.4	1.1	-0.5
Intermittent access intake escalation 2	1.8	1.8	7.3	-0.3	-2.7	0.8	0.6	1.3	0.8
Intermitt. access day 1 inactive lever presses	0.2	0.2	0.4	-0.4	-0.6	0.1	-0.2	0.6	0.3
Intermitt. access day 15 inactive lever presses	0.9	1.0	2.6	-1.3	-1.6	-0.5	-1.0	0.4	-0.1
Intermitt. access escalation Index	0.9	0.8	2.5	-0.2	-1.5	0.0	0.5	1.6	0.0
Intermittent access day 1 total infusions	1.7	2.0	6.3	0.9	2.5	-0.6	-0.4	-1.8	-1.0
Intermittent access day 15 total infusions	0.8	0.9	1.9	-0.6	0.3	-1.1	-1.0	-1.0	-1.4
Intermittent access terminal intake (last 3 days)	0.2	0.2	0.5	0.0	0.3	-0.3	-0.4	-0.7	-0.5
Intermittent access total infusions	1.0	1.1	2.6	0.0	1.5	-0.6	-0.8	-1.6	-0.7
Intermittent access day 1 locomotion	0.8	0.8	1.9	1.2	1.4	0.4	0.6	-0.9	0.1
Intermittent access day 15 total locomotion	3.1	3.3	5.4	-1.6	0.4	-2.3	-2.3	-1.1	-2.3
Intermittent access total locomotion	1.3	1.4	2.2	-1.0	0.8	-1.3	-1.5	-1.1	-1.3
Intermittent access standard deviation	0.9	0.9	2.1	0.8	-1.4	1.0	0.9	0.5	0.7
Cocaine induced anxiety	0.5	0.6	1.7	-1.3	-0.3	-0.2	-1.1	0.0	0.6
Post-drug Anxiety	0.6	0.6	1.8	-1.3	-0.9	-0.4	-0.8	0.6	0.0
Baseline Anxiety	0.5	0.5	1.7	0.0	0.7	-0.8	-0.3	-0.1	-1.3
Lifetime Intake	0.7	0.8	1.8	-0.1	1.2	-0.6	-0.8	-1.3	-0.6
Incentive Sensitization - Responses	0.3	0.3	0.9	-0.2	0.3	-0.8	-0.3	-0.5	-0.9
Incentive Sensitization - Breakpoint	0.3	0.3	0.8	-0.1	0.4	-0.7	-0.3	-0.6	-0.9
Progressive ratio test 1 active lever presses	4.1	4.3	11.5	-0.6	3.4	-1.5	-1.8	-2.5	-1.5
Progressive ratio test 1 breakpoint	4.0	4.1	11.2	-0.5	3.3	-1.5	-1.7	-2.4	-1.6
Progressive ratio test 1 inactive lever presses	4.0	4.2	7.5	-1.8	2.0	-1.9	-2.7	-2.3	-1.3
Progressive ratio test 2 active lever presses	1.2	1.3	1.9	-0.5	1.4	-1.2	-0.9	-1.3	-1.2
Progressive ratio test 2 breakpoint	1.2	1.4	2.8	-0.3	1.7	-1.1	-0.9	-1.4	-1.1
Progressive ratio test 2 inactive lever presses	2.0	2.3	3.8	-0.8	1.1	-1.6	-1.9	-1.7	-1.6
Total sessions with >9 infusions	0.3	0.3	0.8	0.2	0.8	-0.2	-0.3	-0.9	-0.2
Short access day 1 total inactive lever presses	0.4	0.5	1.5	-0.8	-0.2	-0.5	-1.2	-0.6	-0.1
Short access day 10 total inactive lever presses	1.8	2.0	6.8	-0.8	-2.6	0.6	0.0	1.7	1.0
Short access day 1 total infusions	0.6	0.7	1.5	-0.2	0.9	-0.8	-0.7	-1.2	-0.8
Short access day 10 total infusions	0.3	0.3	0.7	0.8	0.6	0.7	0.4	-0.2	0.5
Short access total infusions	0.1	0.1	0.3	0.3	0.4	0.1	-0.1	-0.5	0.1
Short access day 1 locomotion	0.6	0.6	1.3	1.1	-0.1	0.9	0.8	0.3	1.0
Short access day 10 total locomotion	1.2	1.3	3.7	-0.2	-1.9	0.9	0.8	1.2	1.1
Short access total locomotion	2.3	2.4	2.9	1.1	-1.7	1.7	1.7	1.2	1.7
Compulsive drug intake	2.0	2.0	4.1	1.0	-1.4	1.2	2.0	1.7	0.9
One hour access (0.3 mA shock)	0.9	1.0	2.9	0.0	1.7	-0.4	-0.6	-1.6	-0.6
One hour access (shock baseline)	3.0	3.4	6.3	-1.2	2.3	-1.4	-2.2	-2.5	-1.1
Number of responses in last shaping day	0.9	0.9	2.9	0.8	1.7	-0.4	0.1	-1.1	-0.8
Context. condit. distance diff. score	1.0	1.2	2.7	1.1	-0.9	1.1	1.6	0.6	0.8
Locomotion velocity, session 1	0.4	0.4	0.9	-0.1	-1.0	0.7	0.6	0.6	0.7
Locomotion distance, session 1	0.6	0.8	1.5	0.6	-0.8	0.8	1.2	1.2	0.5
Locomotion velocity, session 2	2.1	2.4	5.2	-0.7	-2.3	1.2	1.2	1.8	1.7
Locomotion distance, session 2	1.2	1.7	4.3	-0.1	-1.9	0.6	1.3	2.1	0.5
Locomotion velocity, session 3	0.2	0.2	0.6	0.4	-0.4	0.3	0.7	0.5	-0.0
Locomotion distance, session 3	0.6	0.6	0.9	-0.9	0.4	-1.0	-0.9	-0.6	-0.9
Stereotopy head waving bouts, day 3	1.2	1.4	2.6	1.2	-0.8	1.4	1.6	0.6	1.3
Stereotopy head waving duration, day 3	1.8	2.2	4.4	1.7	-0.7	1.6	2.1	0.9	1.3
Locomotion velocity, session 7	0.6	0.7	2.2	-0.4	0.8	-0.3	-0.9	-1.5	-0.2
Locomotion distance, session 7	0.0	0.0	0.1	0.0	-0.3	0.1	0.4	0.1	-0.2
Stereotopy head waving bouts, day 7	0.4	0.4	1.0	0.4	0.9	-0.4	-0.1	-1.0	-0.7
Stereotopy head waving duration, day 7	1.1	1.4	3.3	0.8	1.8	-0.5	-0.4	-1.8	-0.9
Locomotion velocity, session 8	2.3	2.7	3.6	0.8	-1.8	1.8	1.9	1.6	1.8
Locomotion distance, session 8	4.3	6.5	11.7	2.0	-2.5	2.5	3.4	2.5	2.0
Degree of sensitization distance	3.7	3.8	5.7	1.6	-1.8	2.2	2.4	1.8	1.9
Degree of sensitization stereotypy	1.1	1.2	2.6	0.4	1.6	-0.7	-0.7	-1.6	-1.0
Condit. Reinf. active minus inactive responses	0.6	0.7	1.8	-1.4	-0.5	-0.9	-0.7	0.6	-0.6
Condit. Reinf. active-inactive response ratio	0.6	0.7	1.5	-1.1	-1.2	-0.3	-0.0	1.2	0.0
Condit. Reinf. active responses	0.2	0.2	0.7	-0.4	-0.5	-0.2	-0.0	0.8	-0.2
Condit. Reinf. inactive responses	0.3	0.3	1.2	1.1	0.6	0.6	0.4	0.0	0.3
Incentive salience index mean	0.5	0.7	1.2	-1.1	0.1	-1.0	-1.0	0.3	-0.8
Condit. Reinf. lever presses	0.2	0.3	0.6	-0.1	0.8	-0.5	-0.7	-0.1	-0.6
Time in familiar zone, hab. session 1	1.3	1.3	2.2	1.0	-1.4	1.2	1.5	0.7	0.8
Time in novel zone, hab. session 1	0.5	0.5	1.1	-0.6	1.0	-0.6	-1.0	-0.2	-0.2
Total zone transitions, hab. session 1	0.3	0.5	0.8	0.4	-0.8	0.7	0.8	0.9	0.6
Total locomotion distance, hab. session 1	0.2	0.3	1.0	-0.5	-0.8	0.1	0.1	1.0	0.2
Locomotion velocity, hab. session 1	0.1	0.2	0.8	-0.3	-0.6	0.1	0.1	0.9	0.1
Time in familiar zone, hab. session 2	2.5	2.6	4.9	0.7	-2.2	1.0	1.9	2.2	0.6
Time in novel zone, hab. session 2	2.8	2.8	6.4	-0.2	2.5	-0.7	-1.9	-2.5	-0.2
Total zone transitions, hab. session 2	0.0	0.0	0.1	-0.0	-0.1	0.2	-0.3	0.0	0.2
Total locomotion distance, hab. session 2	0.1	0.1	0.3	-0.4	-0.1	0.1	-0.5	0.2	0.4
Locomotion velocity, hab. session 2	0.1	0.2	0.6	-0.6	-0.0	-0.2	-0.8	0.1	0.1
Novel to familiar place preference ratio	1.4	1.5	2.9	-1.7	0.4	-1.5	-1.5	0.0	-1.3
Novelty place preference	1.3	1.4	2.7	-1.6	0.5	-1.3	-1.5	-0.1	-1.1
Time in novel zone, NPP test	1.0	1.1	2.2	-1.5	0.5	-1.2	-1.4	-0.1	-0.9
Total zone transitions, NPP test	0.0	0.0	0.1	-0.1	-0.2	-0.2	-0.0	0.1	-0.3
Total locomotion distance, NPP test	0.3	0.5	1.1	-1.0	-0.2	-0.8	-0.6	0.2	-0.8
Locomotion velocity, NPP test	0.6	0.8	1.9	-1.4	-0.2	-1.1	-0.8	0.2	-1.1
Pavlov. Cond. lever latency	0.2	0.3	1.1	-1.0	-0.5	-0.3	-0.5	-0.3	0.1
Pavlov. Cond. magazine entry latency	1.2	1.5	4.2	0.7	-1.1	1.0	1.2	2.1	0.9
Pavlov. Cond. change in total contacts	0.4	0.4	0.6	-0.8	0.0	-0.8	-0.8	0.6	-0.7
Pavlov. Cond. index score	0.6	0.8	2.8	0.8	-0.4	0.6	1.0	1.7	0.3
Pavlov. Cond. latency score	0.6	0.8	2.3	0.9	-0.3	0.6	1.0	1.5	0.4
Pavlov. Cond. lever contacts	0.2	0.2	0.7	0.9	0.3	0.3	0.5	0.5	0.1
Pavlov. Cond. magazine entry number	1.0	1.3	4.3	-0.4	1.1	-0.7	-1.0	-2.1	-0.6
Pavlov. Cond. intertrial magazine entries	0.8	0.9	1.7	-0.6	0.8	-0.9	-1.1	-1.3	-0.9
Pavlov. Cond. lever-magazine prob. diff.	0.6	0.8	2.4	0.9	-0.4	0.6	0.9	1.5	0.4
Pavlov. Cond. response bias	0.2	0.2	1.2	0.1	-0.3	0.1	0.3	1.1	0.0
Bone: apparent density	0.5	0.9	2.4	0.0	-1.2	0.6	0.8	1.6	0.6
Bone surface	0.0	0.0	0.2	-0.0	0.2	-0.1	-0.1	0.4	-0.3
Bone volume	0.1	0.1	0.7	0.1	-0.2	0.2	0.2	0.8	0.1
Bone: connectivity density	0.3	0.4	1.2	0.1	-0.9	0.4	0.7	1.1	0.3
Bone: cortical apparent density	0.2	0.3	0.8	0.4	0.9	-0.4	-0.3	0.1	-0.7
Bone: cortical area	2.5	3.8	7.3	-0.4	2.5	-1.4	-2.5	-2.7	-1.1
Bone: cortical porosity	0.4	0.4	1.2	-1.1	-0.3	-0.6	-0.7	-0.5	-0.4
Bone: cortical porosity	0.1	0.2	0.4	-0.4	-0.0	-0.3	-0.3	-0.7	-0.3
Bone: cortical thickness	2.1	3.5	5.8	-0.5	2.2	-1.6	-2.3	-2.4	-1.5
Bone: cortical thickness	0.3	0.3	0.8	0.9	0.3	-0.3	0.3	-0.1	-0.9
Bone: cortical tissue density	0.2	0.3	0.7	0.3	0.9	-0.4	-0.3	0.1	-0.8
Bone: elastic displacement	0.3	0.4	1.1	1.0	0.0	0.6	0.6	0.5	0.4
Bone: elastic work	0.6	0.8	2.5	1.6	0.9	0.8	0.3	-0.7	0.7
Bone: endosteal estimation	0.3	0.6	0.7	0.9	0.6	0.8	0.3	-0.9	0.8
Bone: endosteal perimeter	0.3	0.5	1.3	-0.3	1.0	-0.2	-1.0	-1.1	0.0
Bone: final force	1.1	1.7	4.5	1.5	1.9	0.3	-0.2	-2.1	-0.0
Bone: final moment	0.9	1.4	4.2	1.2	1.6	0.3	-0.3	-2.1	0.2
Bone: marrow area	0.2	0.5	0.7	0.8	0.6	0.8	0.3	-0.8	0.7
Bone: maximum diameter	2.1	3.8	7.2	-0.6	2.6	-1.2	-2.7	-2.6	-0.7
Bone: maximum force	0.6	1.0	2.1	1.4	1.3	0.6	-0.0	-1.5	0.4
Bone: maximum moment	0.5	0.8	1.9	1.1	1.0	0.7	-0.1	-1.4	0.7
Bone: minimum diameter	0.2	0.3	0.5	0.7	0.4	0.7	0.1	-0.6	0.7
Bone: periosteal estimation	0.8	1.5	4.2	0.6	1.9	-0.1	-1.1	-2.0	-0.0
Bone: periosteal perimeter	1.8	3.1	5.7	-0.5	2.3	-1.2	-2.1	-2.4	-1.0
Bone: post-yield work	0.3	0.4	0.9	-0.5	-1.0	0.6	0.1	0.6	0.9
Bone: stiffness	0.5	0.7	2.4	0.2	1.0	-0.5	-0.5	-1.6	-0.7
Bone: tissue strength	2.1	2.0	4.1	1.8	0.3	1.9	1.0	-0.4	2.0
Bone: trabecular number	0.2	0.3	0.7	0.3	-0.5	0.4	0.7	0.9	0.3
Bone: trabecular spacing	0.2	0.2	0.6	0.3	0.8	0.1	-0.4	-0.7	0.2
Bone: trabecular thickness	0.9	1.1	2.4	0.4	-1.3	0.7	1.2	1.6	0.5
Bone: trabecular tissue density	0.1	0.1	0.2	-0.4	-0.4	-0.2	-0.2	0.3	-0.2
Breakpoint value in progressive ratio session	0.2	0.2	0.5	-0.7	0.0	-0.4	-0.6	0.2	-0.3
Distance traveled before self-admin	0.1	0.1	0.4	-0.2	-0.2	0.3	0.3	0.7	0.3
Distance traveled after self-admin	0.6	0.6	1.1	-0.4	0.8	-0.9	-0.7	-0.7	-1.0
Delta time in closed arm before/after self-admin	0.6	0.6	1.0	0.9	0.2	0.8	1.0	0.7	0.6
Delta time in open arm before/after self-admin	2.9	2.8	5.0	-1.8	0.4	-1.9	-2.2	-1.4	-1.6
Diff in mean of infusions in LGA sessions	0.4	0.4	1.2	-0.6	-0.0	-0.9	-0.3	0.4	-1.1
Extinction: sum of active levers before priming	1.9	1.9	3.3	-1.3	1.8	-1.4	-1.5	-0.9	-1.2
Active lever presses in extinction session 6	1.5	1.5	2.1	-1.3	1.1	-1.4	-1.3	-0.6	-1.3
Delta distance traveled before/after self-admin	1.0	1.1	2.4	-0.5	0.5	-1.4	-0.8	-1.0	-1.5
Delta ambulatory time before/after self-admin	0.4	0.5	1.3	-0.6	-0.4	-1.0	-0.3	-0.1	-1.1
Time in closed arm before self-admin	0.4	0.4	0.6	0.8	-0.5	0.8	0.6	0.2	0.8
Time in closed arm after self-admin	1.1	1.2	2.0	1.4	-0.1	1.3	1.2	0.8	1.1
Time in open arm before self-admin	0.2	0.2	0.5	0.7	0.7	0.4	0.3	0.1	0.2
Time in open arm after self-admin	0.5	0.6	1.0	-0.8	0.2	-0.9	-1.0	-0.6	-0.8
Sum of active levers in priming session hrs 5-6	1.1	1.0	1.6	-0.8	1.1	-1.3	-1.0	-0.5	-1.2
Time to tail flick, vehicle, before self-admin	0.4	0.4	0.9	-0.6	-0.2	-0.9	-0.4	0.2	-0.9
Time to tail flick, vehicle, after self-admin	0.2	0.2	0.3	0.5	0.5	0.2	0.6	0.2	-0.1
Time to tail flick, test, before self-admin	0.3	0.3	0.6	0.8	0.5	0.7	0.4	-0.2	0.7
Time to tail flick, test, after self-admin	0.7	0.8	2.5	-0.4	0.5	-0.2	-1.6	-1.2	0.3
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.5	0.7	0.6	0.5	0.6	-0.2	0.1
Delta time to tail flick, test, before/after SA	0.4	0.4	1.2	-0.5	-0.0	-0.2	-1.1	-0.8	0.1
Ambulatory time before self-admin	0.0	0.0	0.1	-0.1	0.3	0.2	0.2	0.3	0.2
Ambulatory time after self-admin	0.3	0.4	0.9	-0.7	0.2	-0.9	-0.3	-0.2	-0.9
Total heroin consumption	0.2	0.3	1.0	0.3	1.0	0.1	-0.1	-0.7	0.1
Area under the delay curve	6.3	6.7	10.4	-2.6	1.3	-3.1	-3.2	-1.6	-3.0
Delay disc. indifference point, 0s delay	8.9	9.7	17.1	-2.4	2.0	-4.0	-3.1	-2.4	-4.1
Delay disc. indifference point, 16s delay	4.1	4.2	7.1	-2.7	1.0	-2.4	-2.6	-1.1	-1.9
Delay disc. indifference point, 2s delay	3.4	3.8	7.2	-1.8	0.5	-2.5	-2.1	-1.1	-2.7
Delay disc. indifference point, 24s delay	4.2	4.1	6.3	-1.6	1.8	-2.3	-2.1	-1.6	-2.5
Delay disc. indifference point, 4s delay	4.0	4.2	6.9	-2.6	-0.3	-2.5	-2.6	-0.3	-2.3
Delay disc. indifference point, 8s delay	1.1	1.2	2.4	-0.8	0.8	-1.2	-1.6	-0.8	-1.1
Delay discount exponential model param	5.6	6.0	9.4	2.5	-1.1	3.0	3.1	1.5	2.8
Delay discount hyperbolic model param	5.8	6.2	9.5	2.6	-1.0	3.1	3.1	1.4	2.9
Fecal boli incidents, locomotor time 1	0.4	0.4	1.4	-0.3	-1.2	0.5	0.4	0.3	0.6
Change in fecal boli incidents, locomotor task	1.2	1.1	1.8	0.6	-0.8	1.1	1.4	1.3	1.1
Time >=10cm from walls, locomotor time 1	1.6	1.6	3.9	1.1	2.0	-0.6	0.2	-1.5	-1.2
Bouts of movement, locomotor time 1	0.4	0.4	1.0	-0.2	1.0	-0.8	-0.1	-0.4	-0.8
Total resting periods, locomotor time 1	0.5	0.5	0.9	-0.3	1.0	-0.9	-0.3	-0.6	-0.9
Rest time, locomotor task time 1	0.6	0.7	1.7	1.0	1.3	0.4	0.3	-1.0	0.4
Distance moved, locomotor task time 1	0.2	0.2	0.7	-0.1	-0.8	0.1	-0.0	0.7	0.1
Vertical activity count, locomotor time 1	0.4	0.4	1.3	-0.3	-0.6	0.4	0.5	1.1	0.4
Time >=10cm from walls, locomotor time 2	0.6	0.7	2.6	1.0	1.6	0.2	0.3	-0.6	0.1
Bouts of movement, locomotor time 2	0.7	0.8	1.5	-1.1	-0.1	-1.2	-0.9	-0.4	-1.1
Total resting periods, locomotor time 2	0.8	0.9	1.6	-0.9	0.3	-1.3	-1.0	-0.6	-1.2
Rest time, locomotor task time 2	0.8	0.9	2.3	1.5	1.1	0.9	0.8	-0.2	0.7
Distance moved, locomotor task time 2	0.3	0.4	1.4	-0.2	-1.2	0.1	0.3	0.8	-0.0
Vertical activity count, locomotor time 2	0.3	0.3	0.9	-0.9	-0.7	-0.4	-0.1	0.5	-0.3
Weight adjusted by age	1.2	1.4	3.7	0.5	1.5	-0.7	-0.7	-1.9	-1.0
Seeking ratio, delayed vs. immediate footshock	0.9	1.1	2.3	-0.7	-1.3	0.9	-0.1	1.5	1.1
Locomotion in novel chamber	0.3	0.4	1.0	-0.1	-1.0	-0.3	0.1	-0.9	-0.7
Locomotion in novel chamber post-restriction	0.2	0.3	0.8	0.6	0.5	0.3	0.9	0.1	0.0
Progressive ratio	0.1	0.1	0.3	-0.0	-0.1	-0.1	-0.2	-0.5	-0.1
Food seeking constrained by brief footshock	1.6	1.9	3.2	-0.9	1.3	-1.6	-1.8	-0.9	-1.6
Seeking ratio, punishment vs. effort	0.4	0.5	1.0	-0.8	0.3	-0.9	-1.0	0.3	-0.7
Run reversals in cocaine runway, females	0.3	0.3	0.9	-0.1	-0.4	-0.5	0.3	0.4	-0.9
Run reversals in cocaine runway, males	0.2	0.2	0.4	-0.1	0.7	-0.3	-0.5	0.4	0.0
Latency to leave start box in cocaine runway	0.9	1.0	1.8	-0.3	1.3	-0.9	-0.8	-1.3	-1.0
Latency to leave start box in cocaine runway, F	0.6	0.7	1.7	0.7	1.3	-0.4	-0.4	-1.0	-0.8
Latency to leave start box in cocaine runway, M	0.8	0.8	1.8	-1.1	0.8	-0.6	-0.8	-1.3	-0.2
Cd content in liver	0.4	0.5	1.0	0.9	-0.4	0.6	1.0	0.6	0.3
Co content in liver	1.3	1.6	2.8	-1.7	0.2	-1.5	-1.4	-0.9	-1.3
Cu content in liver	0.6	0.7	1.7	-1.3	-1.2	-0.7	-0.5	0.0	-0.6
Fe content in liver	1.2	1.4	4.2	-0.8	-2.0	0.7	0.8	1.1	1.1
K content in liver	0.9	0.9	1.7	-0.8	0.5	-1.2	-1.0	-0.8	-1.3
Mg content in liver	1.9	1.9	3.1	-0.9	1.4	-1.3	-1.7	-1.5	-1.3
Mn content in liver	0.3	0.4	1.0	-1.0	-0.4	-0.6	-0.6	0.3	-0.4
Na content in liver	3.9	4.2	7.4	-2.6	1.0	-2.2	-2.7	-1.6	-1.6
Rb content in liver	0.6	0.7	1.3	-0.7	0.5	-0.8	-1.1	-1.0	-0.8
Se content in liver	0.5	0.6	1.4	-0.9	0.6	-0.7	-1.2	-0.7	-0.4
Sr content in liver	0.2	0.2	0.7	-0.4	0.5	-0.1	-0.9	-0.3	0.4
Zn content in liver	0.7	0.8	2.2	0.8	-0.4	1.2	0.2	0.6	1.5