Hub : Genes

Tmem235

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000048231 0.39 0.13 0.0e+00 0.32 0.32 0.31 0.31 1.0e-17 1.3e-17 3.2e-17 4.3e-17
2 Brain gene expression ENSRNOG00000048231 0.38 0.15 0.0e+00 0.31 0.31 0.32 0.32 5.0e-29 2.3e-29 4.1e-30 3.0e-30
3 IL gene expression ENSRNOG00000048231 0.71 0.12 2.1e-09 0.18 0.15 0.18 0.18 3.5e-05 1.9e-04 4.8e-05 3.3e-05
4 LHb gene expression ENSRNOG00000048231 0.31 0.17 2.0e-05 0.18 0.13 0.1 0.14 5.8e-05 5.0e-04 2.7e-03 3.3e-04
5 NAcc gene expression ENSRNOG00000048231 0.53 0.14 0.0e+00 0.38 0.38 0.39 0.39 2.2e-29 2.8e-30 1.6e-30 8.3e-31
6 OFC gene expression ENSRNOG00000048231 0.41 0.19 3.1e-07 0.15 0.13 0.11 0.13 2.2e-04 4.8e-04 1.7e-03 4.7e-04
7 PL gene expression ENSRNOG00000048231 0.39 0.13 0.0e+00 0.38 0.38 0.38 0.38 2.7e-30 1.5e-30 1.2e-30 3.3e-30

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.20.51.0-0.5-0.6-1.0-0.7-0.6-0.7-0.7
BMI without tail0.71.52.41.31.11.21.11.51.21.2
Body weight0.72.84.1-1.4-1.7-2.0-1.8-1.4-1.7-1.7
Epididymis fat weight0.20.40.5-0.5-0.7-0.7-0.6-0.5-0.6-0.7
Glucose0.20.30.5-0.5-0.6-0.7-0.4-0.4-0.6-0.5
Heart weight0.60.91.4-0.8-0.8-1.2-1.0-1.0-0.9-0.9
Left kidney weight3.49.710.7-3.0-3.1-3.3-3.1-3.1-3.0-3.1
Right kidney weight1.23.54.3-1.9-1.9-2.1-1.7-2.0-1.7-1.8
Tail length0.51.52.21.31.11.31.11.51.21.1
Length with tail0.82.83.2-1.5-1.7-1.8-1.8-1.5-1.7-1.8
Length without tail4.810.512.1-3.1-3.1-3.5-3.3-3.3-3.2-3.2
Liver weight, left3.76.06.7-2.3-2.5-2.5-2.6-2.3-2.5-2.5
Liver weight, right0.81.31.8-1.0-1.1-1.4-1.1-1.1-1.1-1.3
Parametrial fat weight0.00.00.00.10.10.0-0.2-0.00.10.0
Retroperitoneal fat weight0.30.91.4-0.8-1.0-1.0-1.2-0.8-1.0-1.1
Intraocular pressure0.30.50.90.50.61.00.40.90.60.5
Extensor digitorum longus weight1.35.06.32.52.42.11.92.42.22.2
Soleus weight0.82.33.61.91.61.11.21.71.61.5
Tibialis anterior weight0.10.30.50.70.60.30.10.60.50.5
Tibia length10.429.232.2-5.2-5.3-5.7-5.6-5.4-5.2-5.4
Number of licking bursts0.00.00.20.2-0.0-0.1-0.20.40.1-0.0
Food consumed during 24 hour testing period0.20.30.80.50.30.60.30.90.40.4
Times rat made contact with spout0.40.50.90.70.60.70.50.90.70.7
Mean time between licks in bursts0.00.00.1-0.2-0.2-0.30.1-0.3-0.3-0.1
Mean num. licks in bursts0.30.40.60.40.60.80.70.40.50.7
Std. dev. time between licks in bursts2.53.03.51.71.71.91.81.81.61.7
Water consumed over 24 hours0.91.11.51.10.90.90.81.21.21.0
Indifference point 0 sec1.11.82.51.21.41.61.21.31.31.4
Indifference point AUC3.54.24.51.92.12.12.02.12.12.1
Indifference point function ln k0.91.31.8-1.0-1.1-1.3-0.9-1.3-1.1-1.1
Indifference point function log k0.91.31.8-1.0-1.1-1.3-0.9-1.3-1.1-1.1
Delay discounting total patch changes 0 sec1.52.43.11.41.61.81.41.51.51.6
Delay discounting total patch changes 12 sec6.28.38.92.83.03.02.82.83.02.9
Delay discounting total patch changes 18 sec3.85.06.42.12.22.51.92.52.22.2
Delay discounting total patch changes 24 sec0.10.20.40.30.40.60.40.40.40.4
Delay discounting total patch changes 6 sec2.53.74.62.02.02.01.82.11.91.9
Delay discounting time to switch 0 sec0.30.50.7-0.5-0.7-0.7-0.9-0.7-0.6-0.7
Delay discounting water rate 0 sec1.32.12.41.31.51.51.51.51.31.3
Delay discounting water rate 12 sec0.00.00.1-0.0-0.0-0.3-0.2-0.1-0.2-0.2
Delay discounting water rate 18 sec0.00.00.10.10.10.30.20.30.10.2
Delay discounting water rate 24 sec1.72.33.31.51.41.61.41.81.51.4
Delay discounting water rate 6 sec0.00.00.10.10.2-0.10.40.10.10.1
Locomotor activity0.00.00.0-0.00.00.10.2-0.10.20.1
Locomotor testing distance0.10.20.3-0.5-0.6-0.3-0.4-0.5-0.4-0.4
Locomotor testing rearing1.01.62.11.21.31.51.11.11.41.4
Light reinforcement 12.95.45.62.42.42.22.32.32.32.3
Light reinforcement 20.70.91.11.01.00.81.01.01.00.9
Reaction time number correct4.36.17.82.62.42.62.32.82.32.4
Reaction time mean minus median0.40.61.0-0.7-0.7-1.0-0.7-1.0-0.4-0.6
Reaction time mean minus median AUC0.50.71.1-0.8-0.8-1.0-0.7-1.0-0.6-0.8
Reaction time num false alarms0.20.20.40.40.50.60.40.30.40.5
Reaction time num false alarms AUC0.30.40.70.60.70.80.60.50.60.6
Reaction time trials correct on left4.36.17.82.62.42.62.32.82.32.4
Reaction time trials on left4.36.17.72.62.42.62.22.82.32.3
Reaction time mean0.10.10.3-0.5-0.4-0.4-0.3-0.6-0.1-0.3
Reaction time mean AUC0.00.10.2-0.3-0.2-0.3-0.1-0.40.1-0.1
Median of all reaction times0.10.10.2-0.5-0.3-0.3-0.2-0.5-0.0-0.2
Reaction time omissions0.30.40.6-0.6-0.6-0.7-0.6-0.8-0.4-0.6
Reaction time false alarm rate0.30.40.9-0.7-0.6-0.5-0.5-1.0-0.6-0.6
Reaction time premature initiation rate1.52.12.21.51.41.31.51.51.41.5
Reaction time premature initiations4.46.37.32.62.52.52.42.72.42.5
Std. dev. reaction times0.10.10.3-0.3-0.3-0.5-0.2-0.50.0-0.2
Reaction time trials completed4.36.17.72.62.42.62.22.82.32.3
Reaction time trials AUC5.07.18.92.82.62.82.43.02.52.6
Social response proportion0.40.50.60.70.70.50.70.80.60.6
Social responses0.40.50.70.80.70.50.70.80.60.6
Social time0.60.81.21.11.00.70.80.80.90.9
Conditioned locomotion0.20.30.40.60.40.50.40.70.40.4
Cocaine response after cond. corrected0.40.50.7-0.7-0.8-0.8-0.4-0.5-0.7-0.8
Cocaine response after cond. not corrected0.10.10.1-0.4-0.4-0.3-0.1-0.2-0.3-0.4
Cocaine response before conditioning0.40.40.80.50.70.90.40.50.80.8
Saline control response1.01.41.91.21.21.21.01.41.11.1
Condit. Reinf. active minus inactive responses0.10.20.4-0.7-0.3-0.2-0.4-0.4-0.4-0.3
Condit. Reinf. active-inactive response ratio0.00.00.0-0.2-0.1-0.0-0.0-0.0-0.1-0.1
Condit. Reinf. active responses0.00.00.1-0.20.10.40.00.20.10.1
Condit. Reinf. inactive responses0.40.50.90.50.70.90.60.80.70.8
Condit. Reinf. lever presses0.91.21.90.91.11.40.91.31.01.1
Condit. Reinf. lever reinforcers received0.00.00.2-0.20.10.40.00.20.10.1
Pavlov. Cond. lever latency0.71.01.8-0.9-0.9-1.3-0.8-1.2-0.8-1.0
Pavlov. Cond. magazine entry latency0.00.00.10.10.10.3-0.10.20.10.1
Pavlov. Cond. change in total contacts0.40.50.90.50.71.00.50.80.50.8
Pavlov. Cond. index score0.30.40.90.50.60.90.40.80.50.7
Pavlov. Cond. latency score0.20.20.50.30.40.70.10.50.30.4
Pavlov. Cond. lever contacts1.11.62.61.21.21.61.01.31.11.3
Pavlov. Cond. magazine entry number0.30.40.6-0.6-0.6-0.8-0.4-0.7-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.70.91.50.80.91.20.71.00.90.8
Pavlov. Cond. lever-magazine prob. diff.0.40.51.00.60.71.00.40.90.60.7
Pavlov. Cond. response bias0.71.01.50.91.01.20.81.10.91.0
Conditioned reinforcement - actives0.80.70.90.80.90.80.80.80.90.9
Conditioned reinforcement - inactives0.30.30.5-0.7-0.5-0.6-0.5-0.7-0.4-0.5
Conditioned locomotion0.60.70.80.70.80.90.80.80.90.9
Intermittent access intake day 1-15 change0.00.00.00.10.20.00.2-0.00.20.2
Intermittent access intake escalation0.10.10.20.30.40.40.40.20.40.4
Intermittent access intake escalation 20.60.60.70.80.80.70.80.80.80.8
Intermitt. access day 1 inactive lever presses2.42.63.0-1.7-1.7-1.6-1.5-1.7-1.5-1.6
Intermitt. access day 15 inactive lever presses0.60.60.70.80.80.80.80.80.80.8
Intermitt. access escalation Index0.50.50.6-0.8-0.8-0.6-0.7-0.6-0.8-0.7
Intermittent access day 1 total infusions0.50.60.6-0.8-0.8-0.7-0.8-0.7-0.7-0.7
Intermittent access day 15 total infusions0.00.00.0-0.2-0.1-0.0-0.1-0.2-0.0-0.1
Intermittent access terminal intake (last 3 days)0.20.20.3-0.5-0.5-0.4-0.5-0.5-0.4-0.5
Intermittent access total infusions0.40.40.5-0.7-0.6-0.6-0.7-0.7-0.6-0.6
Intermittent access day 1 locomotion0.10.10.20.30.30.50.30.40.40.4
Intermittent access day 15 total locomotion0.20.20.3-0.5-0.4-0.4-0.4-0.6-0.3-0.4
Intermittent access total locomotion0.00.10.10.20.20.30.20.20.30.2
Intermittent access standard deviation4.64.95.3-2.1-2.1-2.3-2.2-2.3-2.2-2.2
Cocaine induced anxiety0.10.20.2-0.4-0.4-0.4-0.4-0.4-0.5-0.4
Post-drug Anxiety0.20.30.40.60.50.60.50.60.40.5
Baseline Anxiety0.00.00.00.20.1-0.00.10.00.10.0
Lifetime Intake0.60.70.8-0.9-0.8-0.8-0.8-0.9-0.7-0.8
Incentive Sensitization - Responses0.90.91.1-0.9-0.9-1.1-0.9-0.9-0.9-0.9
Incentive Sensitization - Breakpoint1.11.11.4-1.0-1.0-1.2-1.1-1.0-1.0-1.0
Progressive ratio test 1 active lever presses0.00.00.10.00.10.20.10.10.10.1
Progressive ratio test 1 breakpoint0.00.00.0-0.1-0.10.1-0.1-0.1-0.0-0.1
Progressive ratio test 1 inactive lever presses0.20.20.3-0.5-0.4-0.4-0.4-0.5-0.3-0.4
Progressive ratio test 2 active lever presses0.00.00.0-0.10.00.10.00.00.10.0
Progressive ratio test 2 breakpoint0.00.00.00.10.10.20.10.10.20.2
Progressive ratio test 2 inactive lever presses0.00.00.1-0.3-0.2-0.2-0.1-0.2-0.0-0.1
Total sessions with >9 infusions2.02.22.3-1.5-1.5-1.5-1.5-1.5-1.4-1.5
Short access day 1 total inactive lever presses0.80.80.9-1.0-0.9-1.0-0.8-1.0-0.9-0.9
Short access day 10 total inactive lever presses0.60.71.0-0.9-0.8-0.9-0.7-1.0-0.8-0.8
Short access day 1 total infusions2.12.22.4-1.5-1.5-1.6-1.6-1.4-1.4-1.5
Short access day 10 total infusions2.62.83.1-1.7-1.7-1.6-1.8-1.6-1.7-1.7
Short access total infusions0.80.80.9-0.9-0.9-1.0-0.9-0.9-0.8-0.9
Short access day 1 locomotion0.60.60.8-0.7-0.8-0.9-0.8-0.8-0.8-0.8
Short access day 10 total locomotion0.70.80.9-0.8-0.8-0.9-0.9-0.9-0.8-0.9
Short access total locomotion1.81.92.3-1.3-1.3-1.5-1.3-1.4-1.3-1.3
Compulsive drug intake0.30.30.40.60.60.50.60.50.60.6
One hour access (0.3 mA shock)0.00.00.10.10.10.20.10.20.20.1
One hour access (shock baseline)0.00.00.0-0.2-0.10.1-0.10.0-0.1-0.1
Number of responses in last shaping day2.52.63.0-1.5-1.5-1.7-1.6-1.7-1.5-1.6
Context. condit. distance diff. score0.40.50.6-0.8-0.7-0.5-0.8-0.7-0.6-0.7
Locomotion velocity, session 10.10.10.3-0.2-0.3-0.5-0.1-0.3-0.2-0.3
Locomotion distance, session 13.24.14.42.12.01.92.12.02.12.0
Locomotion velocity, session 20.50.60.70.80.70.70.90.70.80.8
Locomotion distance, session 25.68.09.72.92.82.63.12.82.82.8
Locomotion velocity, session 30.20.20.30.50.50.30.50.40.60.5
Locomotion distance, session 30.30.30.50.70.60.30.60.40.70.6
Stereotopy head waving bouts, day 33.03.64.0-1.8-2.0-1.8-1.9-1.9-2.0-2.0
Stereotopy head waving duration, day 33.23.94.5-2.0-2.0-1.8-2.0-1.9-2.1-2.0
Locomotion velocity, session 70.20.30.40.40.50.60.40.50.50.5
Locomotion distance, session 72.73.54.11.71.82.02.01.81.91.9
Stereotopy head waving bouts, day 74.65.26.0-2.2-2.3-2.2-2.5-2.2-2.2-2.3
Stereotopy head waving duration, day 76.57.98.8-2.8-2.8-2.7-3.0-2.8-2.8-2.8
Locomotion velocity, session 80.30.40.6-0.8-0.7-0.5-0.5-0.6-0.6-0.6
Locomotion distance, session 82.23.33.61.71.71.91.91.71.91.8
Degree of sensitization distance2.92.94.41.41.62.11.81.81.61.6
Degree of sensitization stereotypy1.81.92.2-1.4-1.4-1.4-1.5-1.4-1.3-1.4
Condit. Reinf. active minus inactive responses0.20.20.40.50.50.60.30.50.30.4
Condit. Reinf. active-inactive response ratio0.00.00.2-0.10.00.4-0.10.0-0.10.1
Condit. Reinf. active responses1.31.62.11.51.31.31.11.31.21.2
Condit. Reinf. inactive responses2.42.83.82.01.71.51.51.71.71.6
Incentive salience index mean0.10.10.20.40.40.40.10.40.20.3
Condit. Reinf. lever presses0.20.30.60.70.60.50.30.80.50.5
Time in familiar zone, hab. session 10.20.20.20.40.40.30.50.20.40.4
Time in novel zone, hab. session 10.30.30.4-0.6-0.6-0.6-0.5-0.5-0.6-0.6
Total zone transitions, hab. session 12.02.83.31.71.61.61.81.71.61.7
Total locomotion distance, hab. session 12.13.03.71.91.71.61.71.71.71.7
Locomotion velocity, hab. session 12.63.84.42.12.01.91.92.01.91.9
Time in familiar zone, hab. session 20.00.00.10.10.20.20.30.10.10.1
Time in novel zone, hab. session 20.60.60.7-0.8-0.8-0.7-0.8-0.7-0.7-0.7
Total zone transitions, hab. session 25.47.07.62.62.52.62.82.62.72.7
Total locomotion distance, hab. session 26.07.98.93.02.82.72.82.82.82.8
Locomotion velocity, hab. session 26.38.59.53.12.92.82.93.02.92.9
Novel to familiar place preference ratio1.11.21.70.81.11.31.10.91.21.2
Novelty place preference0.80.91.30.60.91.10.90.81.01.0
Time in novel zone, NPP test1.11.11.60.81.11.31.10.91.11.1
Total zone transitions, NPP test5.17.37.52.72.72.62.72.72.72.7
Total locomotion distance, NPP test8.411.613.13.63.43.23.43.43.43.4
Locomotion velocity, NPP test7.110.111.23.43.23.03.13.23.23.1
Pavlov. Cond. lever latency0.20.20.50.30.40.70.50.30.40.4
Pavlov. Cond. magazine entry latency1.72.22.4-1.5-1.5-1.5-1.5-1.3-1.5-1.5
Pavlov. Cond. change in total contacts0.00.00.0-0.10.0-0.10.00.0-0.00.1
Pavlov. Cond. index score1.01.31.6-1.0-1.1-1.3-1.3-0.9-1.2-1.2
Pavlov. Cond. latency score1.21.62.0-1.1-1.2-1.4-1.3-1.0-1.3-1.3
Pavlov. Cond. lever contacts0.00.00.1-0.0-0.1-0.4-0.20.0-0.1-0.2
Pavlov. Cond. magazine entry number3.24.04.32.02.02.02.11.82.12.0
Pavlov. Cond. intertrial magazine entries2.12.52.91.71.61.71.41.51.51.6
Pavlov. Cond. lever-magazine prob. diff.0.70.91.1-0.9-0.9-1.0-1.0-0.8-1.0-1.0
Pavlov. Cond. response bias1.41.71.9-1.3-1.3-1.4-1.4-1.2-1.3-1.3
Bone: apparent density0.30.50.80.50.60.90.90.70.60.8
Bone surface0.71.31.9-1.3-1.4-0.7-1.0-0.8-1.3-1.2
Bone volume0.10.20.4-0.6-0.60.0-0.6-0.2-0.6-0.4
Bone: connectivity density0.91.32.01.00.91.31.41.21.01.2
Bone: cortical apparent density0.40.50.70.80.80.50.80.60.70.8
Bone: cortical area4.87.28.1-2.6-2.6-2.9-2.8-2.7-2.7-2.6
Bone: cortical porosity2.42.63.3-1.8-1.7-1.5-1.4-1.6-1.7-1.5
Bone: cortical porosity3.23.44.2-2.1-1.9-1.7-1.6-1.9-2.0-1.8
Bone: cortical thickness0.71.23.0-0.8-0.9-1.7-0.9-1.2-1.0-0.9
Bone: cortical thickness0.30.41.1-0.3-0.5-1.0-0.4-0.6-0.6-0.5
Bone: cortical tissue density0.40.60.70.80.80.50.80.60.80.8
Bone: elastic displacement0.60.70.91.00.80.51.00.60.90.9
Bone: elastic work0.91.21.7-0.9-1.0-1.3-1.1-1.2-1.0-1.0
Bone: endosteal estimation1.32.74.1-2.0-1.7-0.9-2.0-1.3-1.7-1.7
Bone: endosteal perimeter4.910.111.6-3.3-3.4-2.6-3.4-2.7-3.4-3.3
Bone: final force2.23.64.0-1.9-1.9-2.0-2.0-1.9-1.8-1.8
Bone: final moment2.54.14.5-2.1-2.0-2.1-2.1-2.0-2.0-1.9
Bone: marrow area1.32.84.2-2.0-1.7-0.9-2.1-1.3-1.7-1.7
Bone: maximum diameter9.216.918.3-4.3-4.2-3.8-4.2-3.9-4.2-4.2
Bone: maximum force2.84.85.5-2.3-2.2-2.2-2.3-2.1-2.1-2.1
Bone: maximum moment3.15.35.9-2.4-2.3-2.3-2.4-2.2-2.3-2.2
Bone: minimum diameter3.66.68.5-2.9-2.5-2.1-2.7-2.6-2.6-2.5
Bone: periosteal estimation3.98.19.8-3.1-2.9-2.4-3.1-2.6-2.9-2.8
Bone: periosteal perimeter7.512.413.3-3.5-3.6-3.4-3.6-3.4-3.6-3.6
Bone: post-yield work0.00.10.1-0.10.00.40.20.20.20.3
Bone: stiffness2.53.94.6-2.1-2.0-2.0-2.0-1.9-1.9-1.9
Bone: tissue strength0.00.00.1-0.00.10.30.2-0.10.20.2
Bone: trabecular number0.20.30.40.50.40.60.50.60.50.5
Bone: trabecular spacing0.10.10.2-0.2-0.2-0.3-0.4-0.3-0.3-0.3
Bone: trabecular thickness0.10.10.20.30.20.40.20.40.00.3
Bone: trabecular tissue density0.10.10.20.40.40.20.10.30.40.3
Breakpoint value in progressive ratio session0.60.60.8-0.8-0.8-0.6-0.9-0.6-0.9-0.9
Distance traveled before self-admin0.50.50.8-0.6-0.7-0.7-0.7-0.9-0.6-0.7
Distance traveled after self-admin0.80.91.30.80.81.20.91.01.01.0
Delta time in closed arm before/after self-admin0.20.20.3-0.4-0.4-0.2-0.5-0.3-0.4-0.5
Delta time in open arm before/after self-admin1.71.61.81.21.31.21.31.21.31.3
Diff in mean of infusions in LGA sessions1.41.52.0-1.2-1.3-1.0-1.4-0.9-1.4-1.4
Extinction: sum of active levers before priming0.10.10.1-0.4-0.3-0.3-0.3-0.2-0.3-0.3
Active lever presses in extinction session 60.00.00.10.10.00.1-0.10.3-0.1-0.1
Delta distance traveled before/after self-admin1.92.02.41.21.31.51.41.61.41.5
Delta ambulatory time before/after self-admin2.02.22.91.31.41.61.41.71.41.5
Time in closed arm before self-admin0.00.00.00.10.2-0.10.1-0.00.10.1
Time in closed arm after self-admin3.03.13.2-1.8-1.7-1.7-1.8-1.8-1.7-1.8
Time in open arm before self-admin0.60.60.8-0.8-0.9-0.8-0.7-0.8-0.7-0.7
Time in open arm after self-admin0.70.70.90.80.80.90.90.90.90.9
Sum of active levers in priming session hrs 5-60.80.81.3-1.1-1.0-0.7-0.8-0.7-0.8-0.8
Time to tail flick, vehicle, before self-admin1.11.21.51.01.10.81.21.11.21.2
Time to tail flick, vehicle, after self-admin2.12.32.9-1.4-1.4-1.7-1.5-1.7-1.5-1.5
Time to tail flick, test, before self-admin0.70.71.00.70.91.00.80.70.80.8
Time to tail flick, test, after self-admin0.90.91.1-1.0-0.9-0.9-0.9-0.8-0.9-1.0
Delta time to tail flick, vehicle, before/after SA0.50.50.7-0.6-0.7-0.6-0.8-0.8-0.8-0.8
Delta time to tail flick, test, before/after SA2.21.92.6-1.2-1.4-1.6-1.4-1.2-1.4-1.4
Ambulatory time before self-admin0.80.81.2-0.8-0.8-0.9-0.9-1.1-0.8-0.9
Ambulatory time after self-admin0.20.20.30.30.30.60.30.50.40.4
Total heroin consumption4.25.15.5-2.3-2.3-2.2-2.3-2.2-2.3-2.2
Area under the delay curve0.50.50.9-0.6-0.7-0.6-1.0-0.5-0.7-0.7
Delay disc. indifference point, 0s delay0.60.70.8-0.9-0.8-0.9-0.8-0.9-0.7-0.8
Delay disc. indifference point, 16s delay0.40.40.70.70.60.70.30.80.60.6
Delay disc. indifference point, 2s delay0.10.10.3-0.3-0.2-0.3-0.5-0.2-0.4-0.4
Delay disc. indifference point, 24s delay0.10.10.10.30.20.20.00.40.30.2
Delay disc. indifference point, 4s delay0.50.60.9-0.7-0.7-0.7-1.0-0.6-0.7-0.8
Delay disc. indifference point, 8s delay2.42.53.0-1.5-1.6-1.5-1.7-1.4-1.6-1.6
Delay discount exponential model param0.70.71.20.80.80.81.10.70.90.9
Delay discount hyperbolic model param0.60.61.10.70.80.71.00.60.80.9
Fecal boli incidents, locomotor time 10.00.00.00.10.10.20.10.20.20.2
Change in fecal boli incidents, locomotor task0.10.10.10.30.30.20.30.20.10.1
Time >=10cm from walls, locomotor time 10.00.00.0-0.2-0.10.20.1-0.1-0.1-0.0
Bouts of movement, locomotor time 10.00.00.10.00.0-0.20.4-0.10.30.2
Total resting periods, locomotor time 10.10.10.20.10.1-0.10.4-0.00.30.3
Rest time, locomotor task time 10.60.71.0-0.8-0.8-1.0-0.6-1.0-0.7-0.8
Distance moved, locomotor task time 10.50.60.90.80.80.90.40.90.70.7
Vertical activity count, locomotor time 12.82.93.41.81.81.81.31.81.71.6
Time >=10cm from walls, locomotor time 20.30.30.60.40.50.40.80.40.60.7
Bouts of movement, locomotor time 20.40.50.7-0.8-0.8-0.7-0.6-0.7-0.6-0.6
Total resting periods, locomotor time 20.50.50.8-0.9-0.9-0.7-0.6-0.8-0.6-0.7
Rest time, locomotor task time 21.21.41.8-1.4-1.3-1.0-1.0-1.3-1.2-1.2
Distance moved, locomotor task time 20.40.50.70.80.80.50.50.60.70.7
Vertical activity count, locomotor time 20.50.50.80.90.90.60.50.70.70.7
Weight adjusted by age0.10.10.2-0.2-0.4-0.2-0.4-0.2-0.5-0.4
Seeking ratio, delayed vs. immediate footshock0.40.40.70.40.60.60.80.30.90.8
Locomotion in novel chamber0.81.01.50.90.91.21.01.20.90.9
Locomotion in novel chamber post-restriction0.20.30.4-0.6-0.6-0.3-0.5-0.4-0.7-0.6
Progressive ratio0.20.20.2-0.5-0.5-0.4-0.4-0.4-0.4-0.5
Food seeking constrained by brief footshock0.80.91.1-1.0-1.0-1.0-0.9-1.0-0.9-1.0
Seeking ratio, punishment vs. effort0.00.00.0-0.2-0.2-0.2-0.2-0.2-0.2-0.2
Run reversals in cocaine runway, females0.00.00.10.10.0-0.2-0.20.1-0.2-0.3
Run reversals in cocaine runway, males0.20.20.3-0.4-0.3-0.6-0.4-0.5-0.4-0.4
Latency to leave start box in cocaine runway0.00.00.10.10.10.20.30.10.30.3
Latency to leave start box in cocaine runway, F0.40.50.60.60.70.70.70.60.80.7
Latency to leave start box in cocaine runway, M0.20.20.20.40.30.40.40.40.40.4
Cd content in liver0.20.20.40.50.50.30.50.40.50.6
Co content in liver0.10.10.20.20.40.50.30.20.40.4
Cu content in liver0.00.00.0-0.0-0.1-0.1-0.0-0.1-0.0-0.1
Fe content in liver0.00.00.0-0.1-0.20.2-0.00.0-0.1-0.1
K content in liver0.10.10.10.20.30.40.20.10.30.3
Mg content in liver1.31.31.61.11.11.31.11.11.11.2
Mn content in liver0.40.50.7-0.5-0.7-0.8-0.8-0.5-0.8-0.8
Na content in liver0.20.30.3-0.5-0.5-0.4-0.5-0.5-0.5-0.5
Rb content in liver2.93.63.91.91.91.91.81.91.92.0
Se content in liver1.01.31.41.21.11.21.11.21.01.0
Sr content in liver0.10.10.2-0.3-0.3-0.5-0.2-0.5-0.3-0.3
Zn content in liver2.12.32.7-1.6-1.5-1.5-1.5-1.6-1.5-1.4