Hub : Genes

Zfp566

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000048138 0.05 0.04 2.0e-05 0.03 0.03 0.03 0.03 1.7e-04 2.9e-04 4.3e-04 2.4e-04
2 BLA gene expression ENSRNOG00000048138 0.16 0.09 1.0e-09 0.14 0.15 0.14 0.14 7.0e-08 2.7e-08 7.5e-08 7.9e-08
3 Brain gene expression ENSRNOG00000048138 0.34 0.14 0.0e+00 0.34 0.13 0.38 0.3 1.3e-32 8.3e-12 1.1e-36 1.6e-28
4 Brain isoform ratio ENSRNOT00000074582 0.04 0.03 7.5e-05 0.03 0.03 0.03 0.02 1.1e-03 6.1e-04 1.8e-03 3.3e-03
5 Brain isoform ratio ENSRNOT00000119618 0.04 0.03 6.2e-05 0.03 0.03 0.03 0.03 2.2e-03 4.7e-04 1.3e-03 2.2e-03
6 Eye alternative TSS ENSRNOT00000074582 0.3 0.2 8.6e-03 0 -0.02 -0.02 -0 2.7e-01 7.5e-01 9.9e-01 3.8e-01
7 IL gene expression ENSRNOG00000048138 0.27 0.17 1.4e-04 0.14 0.1 0.11 0.09 3.8e-04 2.4e-03 1.2e-03 3.9e-03
8 LHb gene expression ENSRNOG00000048138 0.24 0.16 1.7e-04 0.14 0.06 0.15 0.06 3.9e-04 1.3e-02 2.3e-04 1.2e-02
9 Liver gene expression ENSRNOG00000048138 0.06 0.05 4.6e-07 0.03 0.03 0.03 0.03 1.0e-04 2.2e-04 3.4e-04 5.5e-04
10 NAcc gene expression ENSRNOG00000048138 0.43 0.13 0.0e+00 0.35 0.35 0.37 0.36 2.3e-27 4.9e-27 8.1e-29 8.8e-28
11 NAcc intron excision ratio chr1:85320603:85329954 0.02 0.02 9.7e-03 0.03 0.02 0.01 0.02 2.7e-03 1.6e-02 1.1e-01 8.1e-03
12 OFC gene expression ENSRNOG00000048138 0.28 0.14 8.6e-06 0.16 0.09 0.14 0.01 1.4e-04 3.4e-03 3.7e-04 1.4e-01
13 PL gene expression ENSRNOG00000048138 0.14 0.08 4.0e-12 0.16 0.15 0.15 0.16 3.4e-12 8.3e-12 9.6e-12 4.3e-12
14 PL intron excision ratio chr1:85320603:85329954 0.03 0.02 1.8e-03 0.04 0.03 0.03 0.03 1.1e-03 1.7e-03 2.6e-03 2.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.31.01.9-0.9-0.9-0.9-1.01.01.0-1.4-1.3-0.6-0.9-0.9-0.8-0.7-1.0
BMI without tail0.10.20.60.80.30.60.3-0.3-0.20.60.40.60.40.60.40.40.2
Body weight2.510.412.43.33.33.23.3-3.3-2.93.02.93.53.43.23.43.42.9
Epididymis fat weight0.00.10.2-0.20.30.20.2-0.2-0.1-0.4-0.20.30.40.10.40.40.1
Glucose0.20.30.4-0.6-0.5-0.5-0.50.50.5-0.7-0.6-0.5-0.6-0.6-0.6-0.5-0.5
Heart weight0.20.30.90.40.50.70.5-0.5-0.30.60.50.10.80.61.00.30.3
Left kidney weight1.85.38.21.92.62.52.4-2.4-2.11.41.82.52.62.02.62.92.0
Right kidney weight4.111.714.63.23.73.63.5-3.5-3.32.73.03.63.73.33.73.83.2
Tail length5.315.919.44.14.04.04.0-4.0-3.54.44.14.14.03.94.04.03.5
Length with tail8.430.933.55.65.75.55.7-5.7-5.15.85.65.75.75.55.75.55.0
Length without tail4.810.412.82.83.53.03.4-3.4-3.02.92.93.53.53.03.53.62.9
Liver weight, left0.61.01.8-1.3-0.9-1.0-0.90.91.0-1.0-1.0-0.9-0.9-1.3-1.0-0.6-1.0
Liver weight, right0.10.20.5-0.3-0.4-0.3-0.40.40.5-0.1-0.3-0.4-0.3-0.7-0.3-0.0-0.6
Parametrial fat weight0.30.52.2-1.1-0.4-0.3-0.70.70.7-1.5-1.2-0.3-0.3-0.8-0.20.1-0.7
Retroperitoneal fat weight1.85.98.2-2.7-2.3-2.1-2.42.42.4-2.9-2.7-2.4-2.2-2.5-2.2-2.2-2.5
Intraocular pressure0.00.00.20.4-0.00.10.0-0.0-0.10.10.1-0.20.10.30.1-0.20.1
Extensor digitorum longus weight0.20.71.0-0.8-0.8-0.7-0.80.81.0-0.8-0.9-0.8-0.9-0.8-0.9-0.8-1.0
Soleus weight0.20.61.9-1.4-0.6-0.8-0.60.60.7-0.8-0.8-0.2-0.5-1.2-0.5-0.4-0.7
Tibialis anterior weight0.00.20.3-0.5-0.4-0.3-0.40.30.5-0.3-0.4-0.2-0.5-0.4-0.4-0.4-0.5
Tibia length2.26.27.42.22.72.42.6-2.7-2.62.12.32.62.52.32.52.72.6
Number of licking bursts4.04.75.7-2.0-2.1-2.4-2.12.12.3-2.0-2.2-2.2-2.3-2.0-2.3-2.1-2.3
Food consumed during 24 hour testing period0.81.01.11.01.00.81.0-1.0-1.10.91.01.01.01.01.01.01.1
Times rat made contact with spout1.11.32.0-1.4-0.9-1.2-1.01.01.1-1.3-1.3-1.0-1.1-1.4-1.2-0.9-1.1
Mean time between licks in bursts0.00.00.10.30.10.20.1-0.1-0.10.30.20.20.10.40.10.30.1
Mean num. licks in bursts1.11.31.70.81.21.31.2-1.2-1.30.91.11.21.30.91.31.11.3
Std. dev. time between licks in bursts0.91.12.41.50.71.00.8-0.8-0.91.41.20.90.81.50.90.90.9
Water consumed over 24 hours0.30.30.50.50.70.50.6-0.6-0.60.20.40.70.70.40.60.70.6
Indifference point 0 sec0.10.10.30.10.40.20.4-0.4-0.20.40.40.50.40.10.30.60.2
Indifference point AUC0.50.50.9-0.4-0.7-0.7-0.80.80.8-1.0-0.8-0.5-0.7-0.6-0.7-0.6-0.9
Indifference point function ln k0.50.81.20.50.81.00.9-0.9-1.11.00.90.51.00.81.00.61.1
Indifference point function log k0.50.81.20.50.81.00.9-0.9-1.11.00.90.51.00.81.00.61.1
Delay discounting total patch changes 0 sec0.20.30.60.20.60.30.6-0.6-0.40.60.50.70.60.20.40.80.4
Delay discounting total patch changes 12 sec0.10.10.40.60.00.20.1-0.1-0.20.30.40.10.00.50.00.20.2
Delay discounting total patch changes 18 sec0.10.20.4-0.4-0.1-0.7-0.20.20.5-0.5-0.40.1-0.2-0.6-0.40.1-0.5
Delay discounting total patch changes 24 sec0.60.81.21.11.00.61.0-1.0-0.61.00.91.00.81.10.71.00.6
Delay discounting total patch changes 6 sec0.00.10.30.00.2-0.10.1-0.10.20.1-0.00.50.1-0.1-0.10.5-0.2
Delay discounting time to switch 0 sec0.40.51.2-0.5-0.9-0.6-0.80.80.5-0.5-0.6-0.9-1.0-0.4-1.1-0.8-0.5
Delay discounting water rate 0 sec0.81.22.0-1.4-1.0-1.1-1.11.11.4-1.2-1.3-0.7-0.7-1.4-0.7-0.8-1.3
Delay discounting water rate 12 sec0.40.61.00.60.90.60.8-0.8-0.20.90.70.70.90.70.81.00.1
Delay discounting water rate 18 sec0.20.20.7-0.8-0.4-0.4-0.40.40.7-0.2-0.4-0.2-0.1-0.80.1-0.4-0.7
Delay discounting water rate 24 sec0.00.00.1-0.10.1-0.30.1-0.10.10.40.1-0.00.00.00.20.1-0.1
Delay discounting water rate 6 sec0.81.12.60.31.31.01.1-1.1-0.60.70.71.31.40.71.61.40.6
Locomotor activity0.40.71.4-1.0-0.8-0.4-0.90.90.6-1.2-1.0-0.7-0.5-1.1-0.5-0.7-0.6
Locomotor testing distance0.40.71.5-1.1-0.8-0.6-0.90.80.7-1.2-1.0-0.8-0.7-1.0-0.7-0.8-0.6
Locomotor testing rearing2.23.54.3-1.8-1.8-1.8-1.81.82.1-1.8-2.0-1.8-1.9-1.8-1.8-1.8-2.0
Light reinforcement 10.20.30.7-0.8-0.4-0.6-0.40.40.6-0.5-0.5-0.2-0.4-0.7-0.5-0.3-0.6
Light reinforcement 22.83.75.2-2.2-1.9-1.7-2.02.01.8-2.3-2.1-1.7-1.6-2.1-1.6-1.9-1.8
Reaction time number correct0.20.20.9-0.8-0.1-0.1-0.30.30.6-0.6-0.70.10.2-1.00.4-0.1-0.6
Reaction time mean minus median0.20.31.00.40.80.10.6-0.6-0.50.40.40.60.50.20.41.00.5
Reaction time mean minus median AUC0.40.52.00.31.10.20.9-0.9-0.40.40.41.00.80.20.71.40.4
Reaction time num false alarms1.31.72.2-1.4-1.1-1.4-1.21.21.4-1.3-1.4-1.4-1.2-1.5-1.3-1.0-1.4
Reaction time num false alarms AUC1.52.12.8-1.6-1.3-1.4-1.41.41.4-1.6-1.6-1.6-1.3-1.7-1.3-1.2-1.4
Reaction time trials correct on left0.20.20.9-0.8-0.1-0.1-0.30.30.6-0.6-0.70.10.2-1.00.4-0.1-0.6
Reaction time trials on left0.20.31.0-0.8-0.1-0.1-0.30.30.6-0.7-0.70.10.2-1.00.4-0.1-0.6
Reaction time mean0.00.10.2-0.30.4-0.30.2-0.20.0-0.5-0.30.00.1-0.3-0.00.40.0
Reaction time mean AUC0.10.10.5-0.50.2-0.50.0-0.00.1-0.7-0.5-0.00.0-0.5-0.20.3-0.1
Median of all reaction times0.10.10.5-0.50.1-0.4-0.10.10.2-0.7-0.5-0.2-0.1-0.5-0.20.0-0.2
Reaction time omissions0.20.20.7-0.7-0.1-0.7-0.30.30.5-0.6-0.6-0.2-0.1-0.8-0.20.1-0.5
Reaction time false alarm rate0.71.01.7-0.9-1.0-1.1-1.01.00.8-1.0-0.9-1.3-1.2-0.9-1.2-0.9-0.9
Reaction time premature initiation rate0.10.20.40.50.30.20.3-0.3-0.40.50.40.70.50.50.50.30.4
Reaction time premature initiations0.10.10.40.10.20.00.1-0.10.00.1-0.00.60.5-0.20.70.20.1
Std. dev. reaction times0.20.31.20.20.9-0.00.7-0.7-0.30.10.20.60.60.10.41.10.4
Reaction time trials completed0.20.31.0-0.8-0.1-0.1-0.30.30.6-0.7-0.70.10.2-1.00.4-0.1-0.6
Reaction time trials AUC0.30.41.3-1.0-0.2-0.2-0.40.40.7-0.9-0.9-0.00.1-1.10.2-0.2-0.7
Social response proportion3.23.54.51.91.71.81.8-1.8-2.11.92.11.61.81.71.91.62.1
Social responses1.11.52.91.01.11.31.0-1.0-1.40.81.01.31.50.91.71.21.4
Social time2.73.54.21.62.01.61.9-1.9-2.01.51.81.92.01.72.11.82.0
Conditioned locomotion0.30.40.9-0.4-0.8-0.5-0.70.70.6-0.2-0.4-0.9-0.6-0.4-0.5-1.0-0.6
Cocaine response after cond. corrected0.00.00.10.1-0.20.2-0.10.10.20.30.0-0.2-0.30.1-0.3-0.1-0.2
Cocaine response after cond. not corrected0.00.00.10.1-0.10.3-0.10.10.00.0-0.00.0-0.10.2-0.10.1-0.0
Cocaine response before conditioning1.01.31.90.81.31.01.1-1.1-1.30.40.81.31.20.91.21.41.3
Saline control response0.10.10.20.40.00.40.2-0.2-0.10.40.30.20.10.40.2-0.10.2
Condit. Reinf. active minus inactive responses2.63.24.82.21.52.01.6-1.6-1.72.01.91.61.62.21.71.61.6
Condit. Reinf. active-inactive response ratio0.10.10.40.6-0.10.20.0-0.00.10.60.3-0.2-0.20.6-0.2-0.1-0.2
Condit. Reinf. active responses4.66.47.32.72.42.62.4-2.4-2.52.52.62.52.42.72.52.52.5
Condit. Reinf. inactive responses4.75.87.22.12.52.22.4-2.4-2.52.12.32.72.62.12.62.62.5
Condit. Reinf. lever presses8.812.213.33.53.43.63.5-3.5-3.53.63.63.43.43.63.53.43.5
Condit. Reinf. lever reinforcers received4.66.57.42.72.52.62.5-2.5-2.52.62.62.52.52.72.52.52.5
Pavlov. Cond. lever latency5.27.27.7-2.7-2.7-2.7-2.72.72.7-2.6-2.7-2.7-2.6-2.8-2.6-2.7-2.7
Pavlov. Cond. magazine entry latency3.54.14.42.01.92.12.0-2.0-2.12.02.11.92.02.12.11.92.1
Pavlov. Cond. change in total contacts8.912.414.43.73.53.53.6-3.6-3.53.63.63.33.43.83.43.53.4
Pavlov. Cond. index score5.47.17.72.72.72.62.7-2.7-2.72.62.72.62.62.82.72.72.7
Pavlov. Cond. latency score5.36.77.32.72.62.62.6-2.6-2.62.52.62.52.52.72.62.62.6
Pavlov. Cond. lever contacts4.56.37.12.62.52.42.6-2.6-2.52.52.52.52.42.72.42.62.4
Pavlov. Cond. magazine entry number3.84.75.4-2.3-2.2-2.2-2.22.22.2-2.0-2.1-2.1-2.1-2.3-2.2-2.1-2.2
Pavlov. Cond. intertrial magazine entries1.52.03.2-1.8-1.2-1.6-1.31.31.3-1.8-1.6-0.9-1.2-1.8-1.3-1.0-1.3
Pavlov. Cond. lever-magazine prob. diff.5.36.87.22.62.62.62.6-2.6-2.62.52.62.52.62.72.62.62.6
Pavlov. Cond. response bias5.17.08.12.82.72.62.7-2.7-2.62.62.72.62.52.82.52.72.6
Conditioned reinforcement - actives0.10.10.3-0.2-0.4-0.3-0.30.30.30.2-0.1-0.5-0.4-0.5-0.5-0.4-0.3
Conditioned reinforcement - inactives0.80.92.01.10.90.70.9-0.9-0.81.41.10.90.80.90.90.70.8
Conditioned locomotion2.32.84.7-2.0-1.7-1.7-1.71.71.4-1.5-1.5-1.6-1.6-2.2-1.5-1.8-1.4
Intermittent access intake day 1-15 change1.81.82.61.21.51.21.5-1.5-1.01.31.21.51.51.21.51.61.0
Intermittent access intake escalation1.81.82.41.21.51.21.4-1.4-1.01.31.21.41.51.21.51.61.0
Intermittent access intake escalation 21.91.92.71.61.41.31.4-1.4-1.21.51.41.31.31.51.21.41.2
Intermitt. access day 1 inactive lever presses3.94.25.61.72.12.41.9-1.9-2.21.41.82.22.31.72.42.32.2
Intermitt. access day 15 inactive lever presses0.60.71.21.10.80.90.8-0.8-0.80.90.90.60.80.90.80.90.8
Intermitt. access escalation Index0.10.10.3-0.1-0.3-0.4-0.20.20.30.1-0.1-0.4-0.4-0.4-0.3-0.5-0.3
Intermittent access day 1 total infusions2.32.63.9-1.5-1.6-2.0-1.51.51.5-1.1-1.3-1.8-1.8-1.7-1.9-1.8-1.5
Intermittent access day 15 total infusions0.10.10.30.3-0.1-0.50.0-0.00.10.60.3-0.5-0.30.0-0.3-0.2-0.1
Intermittent access terminal intake (last 3 days)0.20.20.50.2-0.4-0.7-0.20.20.30.60.2-0.7-0.6-0.1-0.6-0.6-0.3
Intermittent access total infusions0.40.51.3-0.4-0.7-1.0-0.60.60.5-0.0-0.3-1.1-0.8-0.6-0.8-0.9-0.5
Intermittent access day 1 locomotion0.90.91.6-1.0-1.0-1.2-0.90.90.7-0.8-0.8-1.0-1.0-1.2-1.0-1.0-0.7
Intermittent access day 15 total locomotion0.10.10.4-0.4-0.0-0.5-0.10.10.2-0.2-0.2-0.10.1-0.70.1-0.1-0.2
Intermittent access total locomotion1.11.32.1-1.2-1.1-1.4-1.11.11.0-1.1-1.0-1.1-1.1-1.5-1.1-1.1-1.0
Intermittent access standard deviation5.76.07.22.52.52.22.5-2.5-2.52.72.62.32.42.32.32.42.5
Cocaine induced anxiety0.60.70.90.80.70.90.8-0.8-1.00.60.80.90.80.80.90.81.0
Post-drug Anxiety0.10.10.40.6-0.10.1-0.00.0-0.20.30.2-0.2-0.20.6-0.10.10.2
Baseline Anxiety1.21.31.7-0.8-1.2-1.3-1.21.21.2-1.0-1.1-1.3-1.3-0.7-1.3-1.0-1.2
Lifetime Intake0.70.81.6-0.8-0.9-1.2-0.80.80.7-0.5-0.6-1.3-1.1-1.0-1.1-1.0-0.7
Incentive Sensitization - Responses0.10.10.60.2-0.3-0.2-0.10.1-0.00.20.1-0.8-0.30.1-0.4-0.40.0
Incentive Sensitization - Breakpoint0.10.10.60.1-0.3-0.3-0.10.10.00.10.0-0.8-0.3-0.0-0.4-0.3-0.0
Progressive ratio test 1 active lever presses0.30.30.60.20.60.20.6-0.6-0.80.70.70.60.50.10.50.50.8
Progressive ratio test 1 breakpoint0.70.71.20.50.90.60.9-0.9-1.10.91.00.90.80.40.80.71.1
Progressive ratio test 1 inactive lever presses0.70.81.31.10.80.80.8-0.8-0.81.10.90.70.91.10.80.70.8
Progressive ratio test 2 active lever presses0.10.10.50.40.1-0.20.2-0.2-0.30.70.5-0.4-0.10.2-0.2-0.10.3
Progressive ratio test 2 breakpoint0.10.10.20.2-0.0-0.30.1-0.1-0.30.50.4-0.5-0.20.1-0.3-0.20.3
Progressive ratio test 2 inactive lever presses1.82.04.72.01.01.21.2-1.2-1.62.22.00.51.01.61.10.71.6
Total sessions with >9 infusions1.82.03.4-1.7-1.2-1.6-1.31.31.3-1.4-1.4-1.2-1.4-1.8-1.5-1.0-1.3
Short access day 1 total inactive lever presses0.50.61.51.20.50.60.6-0.6-0.61.21.00.40.51.20.70.20.6
Short access day 10 total inactive lever presses2.42.63.51.91.41.81.5-1.5-1.81.51.61.21.71.71.81.31.8
Short access day 1 total infusions0.20.20.8-0.3-0.4-0.7-0.30.30.40.0-0.2-0.4-0.7-0.4-0.9-0.4-0.4
Short access day 10 total infusions0.91.02.2-1.4-0.8-1.2-0.80.80.6-1.0-0.9-0.9-0.9-1.5-1.0-0.7-0.6
Short access total infusions1.51.72.6-1.6-1.2-1.5-1.21.21.0-1.3-1.2-1.3-1.4-1.6-1.5-1.1-1.0
Short access day 1 locomotion1.31.43.2-1.8-0.7-1.1-1.01.01.2-1.8-1.5-0.3-0.7-1.7-0.8-0.4-1.2
Short access day 10 total locomotion0.60.61.20.30.90.60.8-0.8-1.00.20.61.10.90.20.91.01.0
Short access total locomotion1.31.32.7-1.5-1.0-1.3-1.11.10.9-1.4-1.2-0.8-1.1-1.7-1.1-0.8-0.9
Compulsive drug intake0.30.31.41.10.30.40.4-0.4-0.20.90.60.20.21.20.20.20.2
One hour access (0.3 mA shock)1.11.22.01.21.10.71.2-1.2-1.31.41.30.71.01.00.91.01.3
One hour access (shock baseline)0.10.10.20.00.1-0.10.2-0.2-0.40.40.4-0.20.0-0.10.00.00.4
Number of responses in last shaping day0.20.21.00.9-0.1-0.00.2-0.2-0.11.00.70.1-0.20.6-0.2-0.30.1
Context. condit. distance diff. score0.00.00.1-0.1-0.1-0.3-0.10.10.0-0.0-0.0-0.2-0.2-0.0-0.2-0.2-0.0
Locomotion velocity, session 10.70.71.3-0.9-0.9-0.7-0.90.90.6-1.1-0.9-0.8-0.8-0.9-0.8-1.0-0.6
Locomotion distance, session 10.40.60.80.70.80.60.8-0.8-0.90.70.80.90.70.70.80.50.8
Locomotion velocity, session 20.30.30.6-0.3-0.8-0.4-0.70.70.4-0.5-0.5-0.5-0.7-0.4-0.6-0.7-0.4
Locomotion distance, session 21.31.82.5-1.3-1.4-1.5-1.41.41.2-1.6-1.5-1.2-1.3-1.4-1.3-1.4-1.2
Locomotion velocity, session 30.40.40.6-0.6-0.6-0.7-0.60.60.6-0.7-0.7-0.7-0.7-0.6-0.8-0.5-0.6
Locomotion distance, session 33.23.54.22.01.91.71.9-1.9-1.82.02.01.61.82.01.81.91.8
Stereotopy head waving bouts, day 30.70.81.3-1.1-0.9-0.7-0.90.90.7-1.1-1.0-0.7-0.8-1.1-0.8-0.7-0.7
Stereotopy head waving duration, day 31.51.82.3-1.5-1.4-1.1-1.41.41.2-1.5-1.4-1.2-1.2-1.5-1.2-1.2-1.2
Locomotion velocity, session 70.20.30.50.30.60.30.5-0.5-0.60.30.50.70.60.40.60.50.6
Locomotion distance, session 70.10.10.20.20.40.20.4-0.4-0.30.20.20.30.30.20.30.40.3
Stereotopy head waving bouts, day 70.80.91.3-0.8-1.0-1.0-1.01.01.1-0.5-0.8-1.1-1.1-0.8-1.0-1.1-1.1
Stereotopy head waving duration, day 72.12.63.1-1.5-1.7-1.6-1.71.71.7-1.3-1.5-1.6-1.7-1.5-1.6-1.8-1.7
Locomotion velocity, session 84.04.85.7-2.3-2.2-2.4-2.22.22.0-2.3-2.2-2.1-2.2-2.2-2.2-2.2-2.0
Locomotion distance, session 80.71.01.7-1.0-1.0-1.3-1.01.00.9-0.9-0.9-1.0-1.1-0.9-1.1-1.0-0.9
Degree of sensitization distance0.70.71.1-1.0-0.8-0.8-0.80.80.8-1.0-0.9-0.7-0.8-1.0-0.8-0.7-0.8
Degree of sensitization stereotypy1.21.31.6-1.0-1.1-1.3-1.11.11.3-0.6-0.9-1.2-1.2-1.0-1.2-1.2-1.3
Condit. Reinf. active minus inactive responses0.20.20.4-0.3-0.5-0.3-0.50.50.4-0.6-0.5-0.5-0.4-0.3-0.4-0.5-0.4
Condit. Reinf. active-inactive response ratio0.10.10.2-0.2-0.4-0.1-0.40.40.3-0.4-0.4-0.4-0.4-0.2-0.4-0.2-0.3
Condit. Reinf. active responses2.02.53.4-1.4-1.7-1.4-1.71.71.4-1.8-1.6-1.6-1.5-1.4-1.4-1.8-1.4
Condit. Reinf. inactive responses2.12.54.0-1.5-1.7-1.6-1.61.61.4-1.6-1.6-1.7-1.5-1.5-1.4-2.0-1.4
Incentive salience index mean0.10.10.3-0.2-0.4-0.2-0.50.50.3-0.5-0.5-0.4-0.4-0.1-0.3-0.4-0.3
Condit. Reinf. lever presses0.00.10.20.40.10.30.1-0.1-0.3-0.00.10.20.20.50.20.20.3
Time in familiar zone, hab. session 10.30.30.40.50.50.60.5-0.5-0.50.50.50.50.50.50.50.40.5
Time in novel zone, hab. session 11.01.01.3-1.0-1.0-1.2-1.01.01.1-0.5-0.8-1.1-1.1-1.0-1.1-0.9-1.1
Total zone transitions, hab. session 10.00.00.10.2-0.10.00.0-0.0-0.20.20.20.1-0.10.2-0.0-0.30.2
Total locomotion distance, hab. session 11.82.53.81.71.41.71.5-1.5-1.61.91.81.41.51.71.61.21.6
Locomotion velocity, hab. session 11.11.52.01.31.01.41.1-1.1-1.31.31.31.21.21.31.30.91.3
Time in familiar zone, hab. session 22.82.93.71.61.61.91.6-1.6-1.71.71.71.81.81.61.91.71.7
Time in novel zone, hab. session 21.81.92.3-1.3-1.3-1.5-1.31.31.4-1.3-1.3-1.5-1.4-1.4-1.5-1.4-1.4
Total zone transitions, hab. session 22.73.54.4-1.5-2.0-1.9-2.02.01.9-1.5-1.7-1.8-2.1-1.6-2.1-2.1-1.9
Total locomotion distance, hab. session 20.00.00.1-0.0-0.3-0.1-0.20.20.20.20.0-0.1-0.2-0.0-0.1-0.3-0.2
Locomotion velocity, hab. session 20.10.10.2-0.2-0.4-0.3-0.40.40.3-0.1-0.2-0.2-0.3-0.2-0.2-0.4-0.3
Novel to familiar place preference ratio0.20.20.40.60.40.30.4-0.4-0.20.60.50.20.20.50.20.40.2
Novelty place preference0.10.10.30.50.30.10.3-0.3-0.10.50.30.10.10.40.00.30.1
Time in novel zone, NPP test0.00.00.10.30.1-0.10.1-0.10.10.30.1-0.1-0.10.2-0.20.1-0.1
Total zone transitions, NPP test0.10.10.3-0.5-0.3-0.4-0.30.30.2-0.6-0.4-0.1-0.3-0.5-0.2-0.5-0.2
Total locomotion distance, NPP test2.63.64.11.71.81.91.9-1.9-2.01.92.02.01.91.72.01.82.0
Locomotion velocity, NPP test2.84.14.61.81.92.12.0-2.0-2.22.02.12.12.01.82.11.92.1
Pavlov. Cond. lever latency0.10.20.30.50.40.40.5-0.5-0.40.40.40.20.40.40.40.30.4
Pavlov. Cond. magazine entry latency0.40.50.7-0.8-0.7-0.7-0.70.70.7-0.4-0.6-0.6-0.7-0.8-0.7-0.7-0.7
Pavlov. Cond. change in total contacts0.20.20.3-0.3-0.5-0.5-0.50.50.5-0.3-0.4-0.2-0.5-0.2-0.5-0.4-0.5
Pavlov. Cond. index score0.40.60.7-0.9-0.8-0.7-0.80.80.8-0.7-0.7-0.5-0.8-0.8-0.8-0.7-0.8
Pavlov. Cond. latency score0.20.20.3-0.5-0.5-0.4-0.50.50.5-0.4-0.5-0.3-0.5-0.4-0.5-0.4-0.5
Pavlov. Cond. lever contacts0.10.10.10.20.20.30.2-0.2-0.30.40.30.40.30.30.30.30.3
Pavlov. Cond. magazine entry number0.50.70.80.90.80.80.8-0.8-0.90.50.70.70.80.90.80.80.9
Pavlov. Cond. intertrial magazine entries0.60.81.2-0.4-1.0-0.6-0.90.91.0-0.9-0.9-1.0-0.9-0.4-0.8-1.1-1.0
Pavlov. Cond. lever-magazine prob. diff.0.60.70.9-1.0-0.9-0.9-0.90.90.9-0.7-0.8-0.6-0.9-0.9-0.9-0.8-0.9
Pavlov. Cond. response bias0.10.10.2-0.4-0.4-0.2-0.40.40.4-0.1-0.2-0.2-0.3-0.4-0.3-0.3-0.4
Bone: apparent density0.30.51.10.20.80.60.7-0.7-0.8-0.20.21.10.80.20.71.00.8
Bone surface1.22.13.31.11.61.31.5-1.5-1.70.71.11.81.61.11.61.71.7
Bone volume1.11.82.71.01.51.21.4-1.4-1.50.71.01.61.40.91.41.61.5
Bone: connectivity density0.20.20.7-0.00.60.30.4-0.4-0.6-0.40.00.80.6-0.10.50.80.6
Bone: cortical apparent density2.33.03.7-1.7-1.7-1.8-1.71.71.6-1.9-1.8-1.9-1.7-1.7-1.7-1.7-1.6
Bone: cortical area1.42.12.61.51.41.41.5-1.5-1.51.51.51.41.41.41.41.61.4
Bone: cortical porosity1.82.03.5-1.9-1.2-1.7-1.41.41.2-1.6-1.5-1.1-1.2-1.8-1.3-1.0-1.2
Bone: cortical porosity2.42.53.8-2.0-1.4-1.9-1.61.61.4-1.8-1.7-1.3-1.5-1.9-1.5-1.2-1.4
Bone: cortical thickness0.30.50.80.70.60.70.7-0.7-0.70.90.80.60.60.70.60.80.7
Bone: cortical thickness0.80.91.1-1.1-1.0-0.9-1.01.01.0-0.9-1.0-0.9-0.9-1.1-0.9-0.9-1.0
Bone: cortical tissue density2.73.54.1-1.8-1.8-1.9-1.91.91.8-2.0-2.0-2.0-1.8-1.8-1.8-1.8-1.8
Bone: elastic displacement0.00.00.1-0.2-0.0-0.1-0.00.0-0.00.00.0-0.2-0.0-0.3-0.00.00.0
Bone: elastic work1.82.32.71.41.51.41.5-1.5-1.71.51.61.51.51.31.51.51.6
Bone: endosteal estimation1.83.84.61.91.91.92.0-2.0-2.01.71.92.12.01.92.01.82.0
Bone: endosteal perimeter1.83.74.62.11.91.91.9-1.9-2.01.92.01.81.92.21.91.81.9
Bone: final force1.52.43.11.21.61.41.6-1.6-1.71.31.51.71.61.31.61.81.7
Bone: final moment2.03.23.91.51.91.71.8-1.8-1.91.61.81.91.81.61.82.01.9
Bone: marrow area1.83.94.81.92.02.02.0-2.0-2.11.81.92.22.01.92.11.92.1
Bone: maximum diameter1.42.63.51.71.61.61.6-1.6-1.61.51.61.61.61.71.61.91.6
Bone: maximum force2.54.35.01.92.21.92.1-2.1-2.21.92.02.22.11.92.12.22.2
Bone: maximum moment3.05.25.72.12.42.22.3-2.3-2.42.22.32.42.32.22.32.42.3
Bone: minimum diameter3.97.28.52.82.62.62.7-2.7-2.62.92.92.62.52.92.62.52.6
Bone: periosteal estimation2.24.54.72.12.12.12.1-2.1-2.22.02.12.22.12.12.12.12.1
Bone: periosteal perimeter1.93.24.22.01.62.01.7-1.7-1.81.91.91.51.72.11.81.51.8
Bone: post-yield work1.82.42.81.71.61.41.6-1.6-1.61.41.51.71.51.61.51.61.6
Bone: stiffness1.42.22.41.41.51.41.5-1.5-1.61.41.51.51.41.41.51.51.5
Bone: tissue strength3.23.14.01.71.91.51.9-1.9-1.71.91.91.91.71.61.62.01.7
Bone: trabecular number1.01.52.50.91.41.11.3-1.3-1.40.50.91.61.30.91.31.51.4
Bone: trabecular spacing0.50.61.80.90.60.90.7-0.7-0.41.31.00.60.71.00.70.60.4
Bone: trabecular thickness0.30.30.8-0.6-0.4-0.7-0.40.40.6-0.9-0.8-0.4-0.6-0.6-0.6-0.3-0.6
Bone: trabecular tissue density2.43.44.3-1.8-1.9-1.5-1.91.91.7-1.9-1.9-2.1-1.9-1.8-1.8-2.0-1.7
Breakpoint value in progressive ratio session3.23.65.72.21.51.71.7-1.7-2.12.42.31.41.81.92.01.32.1
Distance traveled before self-admin0.30.30.90.90.00.30.3-0.3-0.80.90.80.2-0.10.80.1-0.30.8
Distance traveled after self-admin4.95.46.32.52.22.22.3-2.3-2.42.42.42.32.32.52.42.02.4
Delta time in closed arm before/after self-admin2.22.23.00.91.61.51.5-1.5-1.61.01.31.51.71.21.71.71.6
Delta time in open arm before/after self-admin1.11.02.3-0.9-0.8-0.8-1.01.01.5-1.0-1.2-0.4-0.9-1.0-1.0-0.6-1.5
Diff in mean of infusions in LGA sessions0.10.10.50.5-0.4-0.0-0.20.2-0.30.60.5-0.2-0.30.3-0.1-0.70.3
Extinction: sum of active levers before priming3.23.34.41.31.92.01.8-1.8-2.01.11.61.82.11.52.12.02.0
Active lever presses in extinction session 63.63.54.91.71.72.11.8-1.8-2.11.51.81.72.11.72.21.72.1
Delta distance traveled before/after self-admin4.34.66.51.92.42.12.2-2.2-1.81.81.92.42.42.02.42.51.8
Delta ambulatory time before/after self-admin4.34.77.01.62.52.02.2-2.2-1.81.61.72.52.61.72.62.61.8
Time in closed arm before self-admin2.22.54.8-0.9-1.7-1.8-1.51.51.6-0.6-1.1-2.0-2.1-0.9-2.2-1.9-1.6
Time in closed arm after self-admin0.40.41.30.90.20.50.4-0.4-0.90.90.9-0.10.01.10.0-0.10.9
Time in open arm before self-admin4.34.56.11.52.32.12.1-2.1-2.51.11.82.52.41.62.42.52.5
Time in open arm after self-admin0.70.72.40.11.10.70.8-0.8-0.2-0.10.11.51.2-0.11.11.50.2
Sum of active levers in priming session hrs 5-60.10.10.40.10.30.10.4-0.4-0.60.10.30.30.4-0.00.50.40.6
Time to tail flick, vehicle, before self-admin0.90.92.2-1.0-1.0-1.0-1.01.00.8-0.8-0.9-1.5-1.0-0.6-0.9-1.0-0.8
Time to tail flick, vehicle, after self-admin0.40.41.11.00.20.80.3-0.3-0.61.00.80.10.30.90.30.10.6
Time to tail flick, test, before self-admin0.80.81.7-0.9-0.5-1.3-0.60.61.1-0.4-0.8-0.9-0.9-0.7-1.2-0.5-1.1
Time to tail flick, test, after self-admin0.10.10.2-0.4-0.0-0.2-0.20.20.5-0.4-0.40.10.1-0.20.00.0-0.5
Delta time to tail flick, vehicle, before/after SA0.90.91.61.10.91.00.9-0.9-0.80.90.91.31.00.71.01.00.8
Delta time to tail flick, test, before/after SA0.10.10.2-0.2-0.20.2-0.30.30.2-0.5-0.30.30.2-0.30.4-0.2-0.2
Ambulatory time before self-admin0.20.20.50.6-0.10.20.2-0.2-0.70.70.60.2-0.10.70.1-0.30.7
Ambulatory time after self-admin8.18.911.02.83.02.73.0-3.0-3.12.72.93.13.22.83.32.83.1
Total heroin consumption0.70.81.70.90.70.60.8-0.8-1.31.11.20.70.70.90.60.51.3
Area under the delay curve0.80.81.71.20.60.80.8-0.8-0.91.31.10.60.61.20.60.60.9
Delay disc. indifference point, 0s delay0.50.62.11.50.30.40.5-0.5-0.71.21.00.30.21.20.3-0.30.7
Delay disc. indifference point, 16s delay2.12.14.32.01.11.41.2-1.2-1.52.11.80.61.01.91.11.11.5
Delay disc. indifference point, 2s delay1.31.42.61.51.11.01.1-1.1-1.01.61.31.11.11.41.10.81.1
Delay disc. indifference point, 24s delay2.82.73.31.71.71.61.6-1.6-1.61.71.71.61.71.71.71.81.6
Delay disc. indifference point, 4s delay0.10.10.30.4-0.1-0.0-0.00.0-0.00.60.3-0.1-0.30.4-0.4-0.2-0.0
Delay disc. indifference point, 8s delay0.10.10.40.00.40.20.4-0.4-0.40.20.30.60.30.20.20.60.5
Delay discount exponential model param0.80.91.6-1.2-0.8-0.9-0.80.80.9-1.3-1.1-0.7-0.7-1.1-0.7-0.8-0.9
Delay discount hyperbolic model param0.60.71.4-1.1-0.7-0.7-0.70.70.8-1.2-1.0-0.6-0.6-1.0-0.6-0.6-0.8
Fecal boli incidents, locomotor time 11.21.32.6-1.3-1.4-0.8-1.31.30.8-1.1-1.0-1.5-0.8-1.1-0.6-1.6-0.7
Change in fecal boli incidents, locomotor task0.10.10.60.50.30.50.2-0.2-0.20.20.10.80.20.30.10.50.1
Time >=10cm from walls, locomotor time 10.00.10.1-0.2-0.2-0.2-0.20.20.1-0.2-0.2-0.3-0.3-0.2-0.4-0.2-0.2
Bouts of movement, locomotor time 11.41.53.81.80.90.91.1-1.1-1.12.01.60.80.91.61.00.31.2
Total resting periods, locomotor time 11.41.63.71.90.81.01.1-1.1-1.31.91.70.80.81.61.00.21.3
Rest time, locomotor task time 10.30.41.7-0.3-1.0-0.2-0.80.80.3-0.3-0.3-0.6-0.6-0.2-0.4-1.3-0.3
Distance moved, locomotor task time 10.10.10.2-0.00.1-0.4-0.00.00.4-0.2-0.3-0.1-0.2-0.2-0.30.5-0.4
Vertical activity count, locomotor time 11.31.43.50.81.51.01.2-1.2-0.70.80.81.71.30.81.21.90.7
Time >=10cm from walls, locomotor time 21.01.12.4-0.5-1.3-0.9-1.21.20.9-0.4-0.7-1.1-1.3-0.6-1.2-1.6-1.0
Bouts of movement, locomotor time 20.10.10.70.5-0.00.10.2-0.2-0.10.80.5-0.0-0.10.5-0.1-0.40.1
Total resting periods, locomotor time 20.10.10.40.3-0.10.10.0-0.00.00.60.30.0-0.10.3-0.2-0.4-0.0
Rest time, locomotor task time 20.10.10.4-0.3-0.6-0.1-0.50.50.50.0-0.1-0.3-0.2-0.2-0.1-0.7-0.4
Distance moved, locomotor task time 20.30.40.9-0.2-0.4-0.9-0.40.40.7-0.6-0.7-0.3-0.9-0.5-0.9-0.1-0.8
Vertical activity count, locomotor time 20.50.61.00.90.90.60.8-0.8-0.40.80.61.00.60.80.51.00.3
Weight adjusted by age0.10.10.3-0.40.1-0.4-0.10.10.5-0.6-0.6-0.1-0.0-0.5-0.20.3-0.5
Seeking ratio, delayed vs. immediate footshock1.11.32.51.41.20.81.2-1.2-1.11.41.30.60.71.60.71.01.2
Locomotion in novel chamber0.10.10.4-0.2-0.40.2-0.30.3-0.3-0.2-0.0-0.30.0-0.30.0-0.60.3
Locomotion in novel chamber post-restriction0.50.61.50.90.20.70.5-0.5-1.21.01.10.30.21.00.3-0.11.2
Progressive ratio0.00.10.2-0.20.10.20.1-0.1-0.4-0.10.00.40.20.00.10.10.5
Food seeking constrained by brief footshock3.84.75.92.02.12.22.1-2.1-2.42.02.22.12.32.22.22.02.4
Seeking ratio, punishment vs. effort0.70.81.51.20.90.80.9-0.9-0.71.21.10.70.81.10.80.80.7
Run reversals in cocaine runway, females0.20.20.4-0.30.60.10.4-0.4-0.2-0.1-0.00.40.6-0.40.50.60.2
Run reversals in cocaine runway, males0.50.51.4-1.1-0.3-0.2-0.50.50.7-1.2-1.0-0.1-0.3-0.9-0.50.2-0.7
Latency to leave start box in cocaine runway0.00.00.2-0.20.3-0.20.1-0.10.2-0.0-0.10.30.2-0.40.20.3-0.2
Latency to leave start box in cocaine runway, F0.20.20.6-0.6-0.0-0.5-0.20.20.6-0.4-0.50.10.0-0.80.00.1-0.6
Latency to leave start box in cocaine runway, M0.00.00.10.40.10.10.2-0.20.10.30.10.10.00.20.10.0-0.1
Cd content in liver0.00.00.2-0.40.1-0.10.1-0.1-0.0-0.3-0.20.00.1-0.30.10.10.0
Co content in liver0.50.61.6-1.0-0.7-0.6-0.80.80.7-1.3-1.1-0.3-0.6-0.8-0.6-0.4-0.7
Cu content in liver0.40.50.90.60.80.40.7-0.7-0.50.90.70.90.60.40.60.90.5
Fe content in liver0.00.00.0-0.1-0.1-0.1-0.10.10.0-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.0
K content in liver0.10.10.20.40.20.30.2-0.2-0.10.20.20.30.20.40.20.40.1
Mg content in liver0.40.40.5-0.5-0.7-0.6-0.70.70.6-0.5-0.6-0.5-0.6-0.6-0.7-0.4-0.7
Mn content in liver0.80.91.2-1.1-1.0-0.8-1.01.00.9-1.0-1.0-0.8-0.8-1.1-0.8-0.9-1.0
Na content in liver2.02.13.81.91.41.41.4-1.4-1.21.81.61.21.21.91.11.31.2
Rb content in liver0.00.00.1-0.2-0.1-0.3-0.20.20.10.20.0-0.1-0.2-0.2-0.2-0.1-0.2
Se content in liver8.310.112.1-3.5-3.2-3.1-3.23.23.1-3.2-3.2-3.1-3.1-3.3-3.1-3.0-3.1
Sr content in liver0.80.71.0-1.0-0.9-0.7-0.90.90.8-1.0-0.9-0.8-0.8-1.0-0.8-0.8-0.8
Zn content in liver0.10.20.3-0.4-0.3-0.4-0.40.40.4-0.6-0.5-0.0-0.4-0.4-0.4-0.1-0.4