Prss55

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000047258 0.08 0.05 6.5e-08 0.06 0.05 0.05 0.05 1.6e-07 5.4e-06 6.7e-06 2.2e-06
2 BLA gene expression ENSRNOG00000047258 0.37 0.12 0.0e+00 0.31 0.29 0.29 0.32 4.1e-17 5.8e-16 5.3e-16 1.9e-17
3 BLA intron excision ratio chr15:38340170:38344928 0.06 0.05 7.5e-03 0.04 0.04 0.03 0.04 2.6e-03 3.2e-03 7.6e-03 2.8e-03
4 BLA mRNA stability ENSRNOG00000047258 0.06 0.04 5.5e-03 0.01 0.01 -0 0 1.5e-01 9.0e-02 3.5e-01 2.4e-01
5 Brain gene expression ENSRNOG00000047258 0.23 0.12 4.2e-15 0.17 0.17 0.18 0.18 1.8e-15 5.1e-16 1.1e-16 1.7e-16
6 Brain intron excision ratio chr15:38319122:38344928 0.04 0.03 4.0e-04 0.02 0.04 0.03 0.04 4.7e-03 8.1e-05 1.4e-03 2.7e-04
7 Brain intron excision ratio chr15:38340170:38344928 0.07 0.04 3.4e-06 0.06 0.06 0.04 0.05 6.7e-06 3.2e-06 9.2e-05 2.2e-05
8 NAcc gene expression ENSRNOG00000047258 0.35 0.22 2.3e-11 0.14 0.14 0.12 0.14 1.2e-10 1.1e-10 5.2e-09 1.1e-10
9 PL gene expression ENSRNOG00000047258 0.19 0.09 1.2e-10 0.16 0.14 0.14 0.15 3.6e-12 1.1e-10 1.1e-10 2.3e-11
10 PL intron excision ratio chr15:38340170:38344928 0.07 0.05 8.3e-04 0.02 0.03 0.01 0.02 1.1e-02 3.9e-03 7.4e-02 8.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail1.54.96.51.1-2.5-2.5-2.2-1.81.8-2.5-2.6-2.3-2.5
BMI without tail0.20.40.7-0.50.60.60.80.6-0.80.70.60.70.7
Body weight1.77.39.12.1-2.6-2.7-3.0-2.12.9-3.0-2.8-2.7-3.0
Epididymis fat weight0.10.10.4-0.70.40.30.3-0.1-0.50.20.20.20.2
Glucose0.10.10.5-0.7-0.2-0.3-0.1-0.20.0-0.4-0.4-0.3-0.3
Heart weight0.10.20.5-0.30.70.30.10.1-0.30.40.60.70.2
Left kidney weight1.23.57.12.2-1.2-1.5-2.5-0.62.7-2.0-1.3-1.4-2.4
Right kidney weight1.43.96.92.6-1.3-1.6-2.5-1.12.6-1.9-1.4-1.5-2.2
Tail length0.72.03.1-0.21.71.51.21.3-0.91.61.81.61.5
Length with tail0.20.92.21.5-0.4-0.6-1.3-0.41.5-0.8-0.5-0.6-0.9
Length without tail3.98.410.92.5-2.7-2.8-3.3-2.23.3-3.1-2.9-2.9-3.2
Liver weight, left2.03.23.81.4-1.8-1.8-2.0-1.51.8-1.9-1.9-1.9-1.9
Liver weight, right1.22.03.50.8-1.6-1.2-1.2-1.91.0-1.4-1.8-1.7-1.0
Parametrial fat weight3.26.310.2-3.22.42.22.81.5-3.02.42.42.62.3
Retroperitoneal fat weight0.72.35.6-2.41.31.31.61.0-1.81.21.31.51.0
Intraocular pressure3.44.77.3-0.82.32.72.22.0-1.62.42.22.22.7
Extensor digitorum longus weight6.726.832.63.7-5.4-5.4-5.3-5.44.5-5.4-5.6-5.7-5.2
Soleus weight0.30.82.2-0.2-1.1-1.0-0.4-1.5-0.2-0.7-1.1-1.1-0.6
Tibialis anterior weight7.525.931.53.8-5.5-5.6-5.2-4.94.6-5.2-5.4-5.4-5.0
Tibia length1.64.411.23.0-1.3-1.7-2.6-0.33.3-2.0-1.3-1.4-2.2
Number of licking bursts0.30.30.8-0.0-0.7-0.8-0.3-0.70.1-0.6-0.9-0.8-0.3
Food consumed during 24 hour testing period0.10.10.50.7-0.2-0.2-0.3-0.10.5-0.1-0.1-0.1-0.1
Times rat made contact with spout0.10.20.5-0.3-0.1-0.2-0.40.70.5-0.30.20.2-0.7
Mean time between licks in bursts3.85.37.4-0.72.42.22.32.5-1.92.72.72.52.5
Mean num. licks in bursts0.40.51.2-0.30.70.70.21.10.10.41.00.90.0
Std. dev. time between licks in bursts1.31.62.50.01.41.21.21.4-0.91.51.61.51.4
Water consumed over 24 hours1.31.52.11.2-1.2-1.2-1.4-0.91.5-1.3-1.1-1.1-1.3
Indifference point 0 sec0.20.20.90.90.00.1-0.6-0.00.9-0.30.0-0.1-0.5
Indifference point AUC0.60.72.3-1.50.50.71.0-0.0-1.30.50.10.30.8
Indifference point function ln k1.21.82.61.5-1.4-1.4-1.6-0.81.6-1.2-0.8-1.0-1.5
Indifference point function log k1.21.82.61.5-1.4-1.4-1.6-0.81.6-1.2-0.8-1.0-1.5
Delay discounting total patch changes 0 sec0.30.51.31.1-0.3-0.3-1.0-0.41.1-0.7-0.3-0.5-0.8
Delay discounting total patch changes 12 sec0.10.10.2-0.20.10.2-0.2-0.20.4-0.4-0.3-0.2-0.3
Delay discounting total patch changes 18 sec0.71.01.6-1.31.11.31.00.3-1.20.80.80.70.8
Delay discounting total patch changes 24 sec0.00.00.10.10.30.20.0-0.40.00.10.1-0.00.2
Delay discounting total patch changes 6 sec0.00.00.2-0.10.40.40.10.1-0.00.0-0.1-0.00.1
Delay discounting time to switch 0 sec0.00.10.2-0.20.20.20.30.4-0.20.20.30.30.2
Delay discounting water rate 0 sec0.91.51.91.0-1.1-1.1-1.4-1.41.2-1.3-1.2-1.2-1.3
Delay discounting water rate 12 sec0.50.81.30.7-0.7-1.1-0.9-1.10.8-0.9-0.7-0.9-0.9
Delay discounting water rate 18 sec3.14.15.11.7-2.0-2.3-2.2-2.01.9-2.1-2.0-2.0-2.1
Delay discounting water rate 24 sec0.20.20.7-0.7-0.2-0.5-0.5-0.40.2-0.5-0.2-0.1-0.8
Delay discounting water rate 6 sec0.91.43.01.3-1.1-0.9-1.1-1.71.0-0.9-1.1-1.3-0.8
Locomotor activity2.84.47.62.3-1.6-1.7-2.6-1.62.7-2.2-1.7-1.8-2.3
Locomotor testing distance0.40.62.21.50.10.1-1.0-0.11.4-0.50.1-0.2-0.7
Locomotor testing rearing0.71.13.11.81.11.0-0.41.11.40.41.10.70.1
Light reinforcement 10.10.20.50.5-0.3-0.3-0.50.20.6-0.5-0.1-0.2-0.7
Light reinforcement 20.40.51.1-0.50.50.70.80.5-1.10.80.60.60.7
Reaction time number correct0.30.51.0-0.30.80.70.50.9-0.30.71.00.90.6
Reaction time mean minus median0.20.30.80.6-0.5-0.3-0.6-0.40.9-0.5-0.6-0.3-0.3
Reaction time mean minus median AUC0.10.10.50.7-0.20.1-0.40.10.7-0.2-0.2-0.0-0.1
Reaction time num false alarms0.71.02.31.3-0.8-0.9-1.3-0.21.5-1.0-0.6-0.6-1.2
Reaction time num false alarms AUC0.60.81.81.1-0.7-0.7-1.2-0.21.3-1.0-0.5-0.5-1.2
Reaction time trials correct on left0.30.51.0-0.30.80.70.50.9-0.30.71.00.90.6
Reaction time trials on left0.50.71.3-0.40.90.80.61.1-0.40.91.11.00.7
Reaction time mean0.20.20.70.40.30.30.40.5-0.10.60.40.60.8
Reaction time mean AUC0.10.20.70.90.20.20.10.30.10.40.20.30.6
Median of all reaction times0.30.51.10.40.50.40.60.6-0.50.90.70.81.0
Reaction time omissions3.14.26.4-0.82.02.01.92.5-1.42.22.42.52.1
Reaction time false alarm rate1.01.42.11.0-1.1-1.1-1.4-0.71.3-1.3-1.1-1.0-1.4
Reaction time premature initiation rate0.30.30.6-0.2-0.4-0.4-0.6-0.70.5-0.8-0.8-0.6-0.7
Reaction time premature initiations0.00.10.2-0.50.10.1-0.2-0.00.2-0.3-0.1-0.0-0.3
Std. dev. reaction times0.10.10.3-0.10.20.30.20.30.00.30.20.50.5
Reaction time trials completed0.50.71.3-0.40.90.80.61.1-0.40.91.11.00.7
Reaction time trials AUC0.50.81.4-0.41.00.90.71.1-0.40.91.21.10.8
Social response proportion3.33.65.2-2.11.91.61.82.3-1.61.82.12.31.5
Social responses3.03.96.3-2.31.91.41.82.4-1.51.92.42.51.5
Social time0.50.62.20.90.70.2-0.41.51.00.10.90.8-0.3
Conditioned locomotion0.30.40.9-0.80.50.30.60.5-0.90.60.70.70.4
Cocaine response after cond. corrected0.50.62.8-1.2-0.00.00.9-0.5-1.70.5-0.1-0.00.6
Cocaine response after cond. not corrected0.40.52.0-1.0-0.1-0.10.8-0.7-1.40.4-0.2-0.20.5
Cocaine response before conditioning0.30.41.30.9-0.2-0.5-0.8-0.11.2-0.6-0.3-0.4-0.6
Saline control response0.10.10.30.30.40.50.3-0.50.00.2-0.1-0.10.6
Condit. Reinf. active minus inactive responses0.20.31.0-1.00.50.80.50.3-0.50.40.40.40.4
Condit. Reinf. active-inactive response ratio0.10.10.5-0.70.20.40.10.50.00.00.10.2-0.0
Condit. Reinf. active responses0.30.41.1-1.00.60.70.50.5-0.60.50.60.70.3
Condit. Reinf. inactive responses0.91.21.6-1.11.21.11.10.8-1.11.11.21.20.9
Condit. Reinf. lever presses0.30.41.60.80.00.0-0.80.51.3-0.40.10.0-0.6
Condit. Reinf. lever reinforcers received0.10.10.6-0.80.30.40.20.3-0.20.10.30.30.1
Pavlov. Cond. lever latency1.52.04.6-2.01.00.91.70.5-2.21.41.01.11.4
Pavlov. Cond. magazine entry latency2.32.63.21.3-1.6-1.6-1.8-1.51.7-1.7-1.6-1.6-1.7
Pavlov. Cond. change in total contacts2.53.55.72.4-1.4-1.3-2.1-1.82.2-1.8-1.9-2.1-1.5
Pavlov. Cond. index score2.63.44.92.1-1.6-1.5-2.1-1.62.2-1.8-1.7-1.8-1.7
Pavlov. Cond. latency score2.53.14.92.2-1.5-1.4-2.0-1.42.2-1.7-1.6-1.7-1.6
Pavlov. Cond. lever contacts1.11.54.01.9-0.8-0.7-1.5-0.52.0-1.1-0.8-0.9-1.1
Pavlov. Cond. magazine entry number1.01.31.9-0.51.11.11.31.1-1.11.31.11.11.4
Pavlov. Cond. intertrial magazine entries7.49.613.2-2.33.13.12.93.6-2.43.13.63.62.8
Pavlov. Cond. lever-magazine prob. diff.2.53.34.52.0-1.6-1.5-2.0-1.62.1-1.8-1.8-1.9-1.7
Pavlov. Cond. response bias1.92.74.91.7-1.4-1.2-1.9-1.22.2-1.7-1.5-1.5-1.7
Conditioned reinforcement - actives9.99.812.1-2.53.12.93.42.5-3.33.53.43.13.4
Conditioned reinforcement - inactives1.61.93.0-0.31.41.31.41.4-1.01.61.51.31.7
Conditioned locomotion3.34.07.2-2.71.71.72.30.9-2.72.01.71.72.0
Intermittent access intake day 1-15 change1.01.01.4-0.51.11.10.91.2-0.71.01.21.00.9
Intermittent access intake escalation1.11.11.5-0.81.11.21.11.2-0.91.11.11.01.0
Intermittent access intake escalation 20.70.71.0-0.40.90.90.90.7-0.80.90.80.71.0
Intermitt. access day 1 inactive lever presses1.01.11.9-0.21.01.21.01.4-0.61.11.11.01.2
Intermitt. access day 15 inactive lever presses0.30.42.61.6-0.0-0.3-0.20.50.60.30.1-0.00.5
Intermitt. access escalation Index0.50.51.4-1.20.60.70.80.6-0.80.50.50.50.4
Intermittent access day 1 total infusions0.40.51.3-1.00.30.31.00.0-1.10.70.30.30.8
Intermittent access day 15 total infusions2.32.63.8-1.71.51.61.91.3-1.81.61.41.31.8
Intermittent access terminal intake (last 3 days)1.71.83.1-1.31.11.31.81.0-1.61.41.10.91.7
Intermittent access total infusions1.71.93.5-1.71.11.21.70.9-1.91.41.11.01.4
Intermittent access day 1 locomotion0.10.10.3-0.1-0.3-0.2-0.0-0.5-0.1-0.3-0.5-0.5-0.1
Intermittent access day 15 total locomotion0.91.01.9-0.80.90.91.30.3-1.31.10.70.61.4
Intermittent access total locomotion0.10.10.3-0.4-0.00.10.5-0.1-0.60.2-0.1-0.10.4
Intermittent access standard deviation0.60.60.9-0.40.70.90.90.8-0.60.91.00.80.9
Cocaine induced anxiety0.20.20.50.5-0.2-0.2-0.6-0.50.7-0.4-0.2-0.2-0.4
Post-drug Anxiety0.60.72.51.6-0.3-0.2-1.1-0.01.5-0.6-0.2-0.2-0.7
Baseline Anxiety0.20.20.50.7-0.4-0.4-0.40.10.6-0.4-0.2-0.4-0.5
Lifetime Intake2.12.43.9-1.71.31.41.91.1-2.01.61.41.21.6
Incentive Sensitization - Responses3.53.55.0-0.51.81.81.92.2-1.42.12.11.82.1
Incentive Sensitization - Breakpoint3.53.55.4-0.41.81.91.92.3-1.32.12.21.92.1
Progressive ratio test 1 active lever presses0.30.31.6-1.30.20.30.70.1-0.90.20.10.10.3
Progressive ratio test 1 breakpoint0.30.31.9-1.40.20.30.70.1-0.80.20.00.00.3
Progressive ratio test 1 inactive lever presses1.41.52.6-0.51.11.31.41.0-1.11.41.21.01.6
Progressive ratio test 2 active lever presses3.43.74.7-1.71.81.82.22.0-2.02.01.91.72.0
Progressive ratio test 2 breakpoint2.32.53.4-1.21.51.51.81.8-1.51.71.61.51.6
Progressive ratio test 2 inactive lever presses2.02.33.4-0.71.61.41.71.6-1.31.81.61.51.8
Total sessions with >9 infusions2.02.13.3-0.51.41.41.71.4-1.51.81.51.21.8
Short access day 1 total inactive lever presses0.40.40.8-0.90.60.60.70.6-0.70.60.60.50.5
Short access day 10 total inactive lever presses0.80.91.1-0.90.91.01.01.0-0.91.00.91.01.0
Short access day 1 total infusions3.33.54.9-1.41.61.52.21.8-2.12.22.01.62.1
Short access day 10 total infusions0.20.20.7-0.8-0.2-0.00.3-0.7-0.5-0.1-0.3-0.30.1
Short access total infusions0.70.81.4-0.80.70.71.20.5-1.21.00.80.61.1
Short access day 1 locomotion0.50.50.9-0.00.70.50.70.5-0.71.00.90.80.9
Short access day 10 total locomotion0.60.71.21.1-0.9-1.0-0.8-0.50.9-0.7-0.8-0.8-0.7
Short access total locomotion0.10.10.60.8-0.2-0.3-0.1-0.10.30.0-0.1-0.20.1
Compulsive drug intake0.20.20.7-0.3-0.4-0.3-0.5-0.20.4-0.7-0.4-0.3-0.8
One hour access (0.3 mA shock)1.01.23.1-1.80.80.91.40.4-1.50.90.80.81.0
One hour access (shock baseline)2.12.43.6-1.71.41.41.91.0-1.91.71.41.31.8
Number of responses in last shaping day0.10.10.4-0.20.30.30.5-0.4-0.50.40.10.20.6
Context. condit. distance diff. score1.61.95.5-2.30.90.91.51.2-2.01.11.01.20.8
Locomotion velocity, session 10.30.30.70.2-0.4-0.3-0.7-0.30.8-0.7-0.4-0.4-0.8
Locomotion distance, session 10.10.10.50.20.10.2-0.40.00.7-0.30.10.1-0.5
Locomotion velocity, session 20.60.81.9-0.3-1.0-0.5-1.0-0.31.1-1.2-0.6-0.4-1.4
Locomotion distance, session 20.20.20.90.10.20.3-0.40.60.9-0.20.50.4-0.4
Locomotion velocity, session 30.70.91.50.9-0.8-0.7-1.1-0.51.2-1.0-1.0-1.0-0.9
Locomotion distance, session 30.40.40.70.3-0.3-0.7-0.7-0.60.7-0.8-0.8-0.9-0.7
Stereotopy head waving bouts, day 30.50.62.00.90.60.90.80.4-0.41.00.50.41.4
Stereotopy head waving duration, day 30.50.62.61.6-0.6-0.3-0.5-0.70.8-0.3-0.8-0.70.1
Locomotion velocity, session 71.61.75.6-2.41.31.20.91.7-1.00.71.21.30.2
Locomotion distance, session 72.63.36.3-2.51.71.41.81.9-1.91.61.81.91.4
Stereotopy head waving bouts, day 71.92.23.01.6-1.3-1.4-1.6-1.01.7-1.6-1.5-1.4-1.5
Stereotopy head waving duration, day 72.63.15.42.3-1.6-1.4-1.9-1.41.9-1.7-1.8-1.8-1.6
Locomotion velocity, session 80.30.30.8-0.7-0.7-0.5-0.5-0.10.4-0.7-0.3-0.2-0.9
Locomotion distance, session 80.40.52.1-1.40.40.60.51.0-0.50.30.70.8-0.0
Degree of sensitization distance6.36.48.9-3.02.22.22.72.5-2.72.52.62.72.2
Degree of sensitization stereotypy2.02.13.41.0-1.4-1.4-1.6-1.21.5-1.7-1.5-1.4-1.8
Condit. Reinf. active minus inactive responses0.60.61.80.8-0.3-0.4-1.1-0.11.4-0.9-0.4-0.4-1.1
Condit. Reinf. active-inactive response ratio0.10.10.20.40.30.30.20.2-0.10.40.30.20.5
Condit. Reinf. active responses0.80.92.20.7-0.6-0.8-1.2-0.31.5-1.1-0.6-0.6-1.3
Condit. Reinf. inactive responses0.30.40.70.4-0.5-0.6-0.8-0.30.8-0.7-0.4-0.4-0.8
Incentive salience index mean2.83.35.81.3-1.6-1.9-2.2-0.92.4-2.1-1.5-1.4-2.4
Condit. Reinf. lever presses3.85.18.41.3-2.1-2.7-2.6-1.32.7-2.6-1.9-1.8-2.9
Time in familiar zone, hab. session 10.30.32.0-1.40.30.00.50.1-0.70.20.40.30.1
Time in novel zone, hab. session 11.00.91.81.3-0.8-0.4-0.8-1.10.9-0.9-1.4-1.3-0.4
Total zone transitions, hab. session 10.40.61.1-0.0-0.6-0.3-0.8-1.00.6-1.0-0.8-0.8-1.0
Total locomotion distance, hab. session 10.00.10.1-0.30.20.4-0.1-0.30.1-0.2-0.1-0.2-0.2
Locomotion velocity, hab. session 10.10.10.20.1-0.0-0.0-0.4-0.40.5-0.4-0.1-0.2-0.5
Time in familiar zone, hab. session 20.30.40.9-0.60.50.40.70.2-0.90.70.40.40.7
Time in novel zone, hab. session 20.10.10.50.1-0.2-0.1-0.50.00.7-0.5-0.2-0.2-0.5
Total zone transitions, hab. session 20.71.02.00.6-0.9-1.1-1.2-0.61.2-1.1-0.6-0.7-1.4
Total locomotion distance, hab. session 20.40.51.5-0.0-0.6-0.8-0.8-0.40.8-0.9-0.4-0.4-1.2
Locomotion velocity, hab. session 20.71.02.40.2-0.9-1.1-1.2-0.61.1-1.2-0.7-0.7-1.5
Novel to familiar place preference ratio0.30.30.8-0.90.40.70.30.8-0.10.20.50.60.2
Novelty place preference0.30.30.9-0.80.40.60.10.90.20.10.50.6-0.0
Time in novel zone, NPP test0.20.20.7-0.60.30.60.00.80.3-0.00.40.4-0.1
Total zone transitions, NPP test0.20.31.10.0-0.4-0.6-0.70.10.7-0.6-0.0-0.0-1.0
Total locomotion distance, NPP test0.81.12.6-0.61.20.90.71.6-0.30.91.51.40.4
Locomotion velocity, NPP test0.81.12.6-0.71.20.90.71.6-0.40.91.51.40.5
Pavlov. Cond. lever latency1.82.35.2-0.51.82.31.70.6-1.51.71.10.92.0
Pavlov. Cond. magazine entry latency1.01.31.91.0-1.1-1.2-1.3-0.51.4-1.2-0.9-0.9-1.3
Pavlov. Cond. change in total contacts4.24.46.61.1-2.3-2.3-2.4-1.52.3-2.4-1.9-1.8-2.6
Pavlov. Cond. index score4.35.58.51.6-2.5-2.9-2.7-1.32.5-2.6-2.0-1.9-2.9
Pavlov. Cond. latency score3.44.37.01.3-2.2-2.6-2.4-1.02.3-2.3-1.7-1.6-2.6
Pavlov. Cond. lever contacts3.03.56.21.1-2.0-2.5-2.2-0.72.1-2.0-1.4-1.2-2.4
Pavlov. Cond. magazine entry number2.43.04.0-1.51.72.02.01.1-2.01.91.61.52.0
Pavlov. Cond. intertrial magazine entries0.00.00.20.50.20.2-0.2-0.10.3-0.10.1-0.0-0.2
Pavlov. Cond. lever-magazine prob. diff.5.16.49.41.7-2.7-3.1-2.9-1.52.7-2.8-2.2-2.1-3.1
Pavlov. Cond. response bias3.74.56.41.6-2.3-2.5-2.4-1.32.2-2.3-1.9-1.8-2.5
Bone: apparent density0.40.61.90.10.90.80.21.40.20.51.11.10.2
Bone surface0.20.30.70.10.70.6-0.10.90.40.20.80.8-0.2
Bone volume0.10.10.3-0.20.30.1-0.30.50.5-0.20.50.5-0.5
Bone: connectivity density1.72.65.90.51.81.91.02.4-0.41.52.02.01.3
Bone: cortical apparent density0.20.20.9-0.2-0.30.00.5-0.6-0.90.3-0.4-0.40.6
Bone: cortical area1.01.52.2-0.6-1.2-1.4-1.0-1.50.6-1.4-1.3-1.3-1.4
Bone: cortical porosity2.93.14.21.3-2.0-2.0-1.9-1.61.8-1.8-1.8-1.6-1.8
Bone: cortical porosity1.92.12.81.0-1.6-1.7-1.5-1.51.4-1.5-1.4-1.3-1.4
Bone: cortical thickness1.62.74.3-0.3-1.7-1.7-1.3-2.10.9-1.8-2.1-2.0-1.6
Bone: cortical thickness1.21.43.2-1.8-1.1-1.0-0.5-1.4-0.1-1.3-1.4-1.2-1.3
Bone: cortical tissue density0.20.20.9-0.2-0.30.10.5-0.6-1.00.3-0.4-0.40.7
Bone: elastic displacement0.30.30.80.00.70.70.6-0.2-0.40.60.40.30.9
Bone: elastic work0.40.51.20.9-0.4-0.2-0.7-1.10.9-0.7-0.7-0.7-0.5
Bone: endosteal estimation0.00.10.3-0.10.40.1-0.10.40.30.00.50.5-0.3
Bone: endosteal perimeter0.30.61.6-0.30.90.60.51.0-0.20.71.31.20.3
Bone: final force1.22.03.9-0.0-1.4-1.5-1.5-1.21.2-1.7-1.4-1.4-2.0
Bone: final moment1.21.93.40.3-1.3-1.5-1.5-1.21.3-1.6-1.3-1.3-1.8
Bone: marrow area0.10.10.4-0.20.40.1-0.00.50.20.10.60.6-0.3
Bone: maximum diameter0.30.51.1-0.9-0.6-0.8-0.3-1.0-0.0-0.7-0.7-0.6-0.7
Bone: maximum force1.42.54.2-0.1-1.5-1.6-1.6-1.71.2-1.9-1.6-1.6-2.0
Bone: maximum moment1.32.33.70.2-1.4-1.6-1.6-1.61.4-1.8-1.5-1.5-1.9
Bone: minimum diameter0.40.81.6-0.3-0.8-0.9-0.9-0.90.8-1.1-0.8-0.8-1.3
Bone: periosteal estimation0.10.20.6-0.6-0.3-0.5-0.4-0.40.3-0.5-0.3-0.2-0.7
Bone: periosteal perimeter0.10.10.3-0.5-0.1-0.4-0.2-0.10.2-0.30.00.0-0.5
Bone: post-yield work0.81.17.9-2.8-0.1-0.20.5-0.7-1.2-0.2-0.3-0.2-0.3
Bone: stiffness1.11.83.50.3-1.4-1.6-1.5-0.91.2-1.6-1.3-1.2-1.9
Bone: tissue strength0.50.51.10.20.90.70.70.6-0.40.90.80.71.1
Bone: trabecular number0.71.12.9-0.01.11.10.61.7-0.20.91.41.40.6
Bone: trabecular spacing1.52.05.00.2-1.6-1.8-0.7-2.20.2-1.1-1.8-1.8-0.6
Bone: trabecular thickness0.91.12.60.4-0.8-0.8-1.3-0.61.3-1.3-0.8-0.8-1.6
Bone: trabecular tissue density1.82.65.11.4-1.9-1.3-1.3-2.30.9-1.4-2.0-2.0-1.0
Breakpoint value in progressive ratio session0.40.40.8-0.7-0.4-0.8-0.3-0.90.1-0.7-0.8-0.5-0.6
Distance traveled before self-admin0.20.20.30.10.40.50.20.1-0.30.50.60.40.5
Distance traveled after self-admin0.10.10.3-0.20.20.20.3-0.1-0.60.40.40.20.3
Delta time in closed arm before/after self-admin0.10.10.4-0.00.20.40.10.7-0.10.30.60.5-0.1
Delta time in open arm before/after self-admin0.20.20.7-0.10.50.50.60.2-0.50.60.10.00.8
Diff in mean of infusions in LGA sessions2.62.93.81.4-1.4-1.6-1.9-1.71.9-1.9-2.0-1.6-1.7
Extinction: sum of active levers before priming0.30.31.2-1.10.60.30.60.2-0.70.50.40.50.4
Active lever presses in extinction session 60.50.50.9-0.90.90.70.70.5-0.60.60.70.80.6
Delta distance traveled before/after self-admin0.20.20.3-0.0-0.6-0.6-0.3-0.40.2-0.4-0.6-0.5-0.3
Delta ambulatory time before/after self-admin0.00.00.1-0.3-0.1-0.10.1-0.4-0.2-0.1-0.3-0.30.0
Time in closed arm before self-admin3.23.74.82.2-1.8-1.7-2.1-1.31.9-2.0-2.0-2.0-2.0
Time in closed arm after self-admin1.81.94.31.2-1.2-1.2-1.8-0.61.5-1.6-1.0-1.1-2.1
Time in open arm before self-admin1.11.22.2-1.11.11.11.00.9-0.81.11.41.50.9
Time in open arm after self-admin1.41.52.7-0.41.31.41.31.1-1.01.41.21.11.6
Sum of active levers in priming session hrs 5-60.80.81.5-1.20.90.80.90.4-1.00.90.80.80.9
Time to tail flick, vehicle, before self-admin2.52.63.21.3-1.4-1.6-1.7-1.51.8-1.7-1.8-1.6-1.6
Time to tail flick, vehicle, after self-admin1.21.22.20.4-1.1-0.9-1.1-1.31.0-1.3-1.5-1.1-1.0
Time to tail flick, test, before self-admin0.10.10.30.50.00.2-0.30.10.5-0.10.10.1-0.1
Time to tail flick, test, after self-admin3.83.95.1-1.11.71.82.12.1-1.72.32.32.12.2
Delta time to tail flick, vehicle, before/after SA0.50.50.9-0.80.71.00.60.8-0.70.60.80.80.5
Delta time to tail flick, test, before/after SA2.82.53.5-0.91.41.21.81.7-1.71.91.71.51.8
Ambulatory time before self-admin0.00.00.0-0.10.10.1-0.1-0.1-0.10.00.20.1-0.2
Ambulatory time after self-admin0.20.20.70.1-0.5-0.4-0.4-0.8-0.0-0.3-0.4-0.4-0.4
Total heroin consumption0.20.30.80.4-0.5-0.7-0.3-0.90.3-0.4-0.7-0.6-0.1
Area under the delay curve5.55.87.90.4-2.6-2.7-2.3-2.51.7-2.8-2.8-2.5-2.8
Delay disc. indifference point, 0s delay0.10.10.3-0.1-0.4-0.6-0.2-0.30.1-0.3-0.1-0.3-0.4
Delay disc. indifference point, 16s delay3.13.16.0-0.1-2.0-1.8-1.5-2.40.8-2.0-2.2-1.8-1.8
Delay disc. indifference point, 2s delay0.60.71.10.2-1.0-1.0-0.8-0.80.6-0.9-0.8-0.9-0.9
Delay disc. indifference point, 24s delay3.73.65.6-0.5-2.2-1.9-1.6-2.20.9-2.2-2.4-1.9-2.2
Delay disc. indifference point, 4s delay5.25.47.61.1-2.5-2.8-2.3-2.11.9-2.6-2.6-2.5-2.5
Delay disc. indifference point, 8s delay6.16.38.80.7-2.6-2.7-2.4-2.61.8-2.9-3.0-2.7-2.9
Delay discount exponential model param6.16.58.7-0.42.72.92.42.6-1.83.03.02.72.9
Delay discount hyperbolic model param6.26.68.9-0.62.83.02.42.6-1.92.93.02.72.8
Fecal boli incidents, locomotor time 10.10.10.4-0.60.0-0.3-0.0-0.1-0.2-0.1-0.10.1-0.2
Change in fecal boli incidents, locomotor task0.10.10.40.6-0.0-0.0-0.20.40.5-0.00.10.10.0
Time >=10cm from walls, locomotor time 10.20.20.70.90.60.4-0.30.60.70.10.50.30.0
Bouts of movement, locomotor time 10.40.41.6-0.0-0.5-0.3-0.80.40.7-0.8-0.3-0.3-1.3
Total resting periods, locomotor time 10.20.21.0-0.7-0.3-0.1-0.40.50.2-0.6-0.1-0.1-1.0
Rest time, locomotor task time 10.40.41.5-0.5-0.5-0.5-0.60.10.4-0.9-0.5-0.3-1.2
Distance moved, locomotor task time 10.60.71.90.10.81.00.90.1-0.71.10.70.61.4
Vertical activity count, locomotor time 10.40.51.71.00.10.20.5-1.0-0.30.7-0.0-0.31.3
Time >=10cm from walls, locomotor time 20.20.21.11.00.50.2-0.10.60.30.30.60.30.1
Bouts of movement, locomotor time 22.22.43.80.2-1.7-1.6-1.6-1.21.2-1.9-1.8-1.6-1.9
Total resting periods, locomotor time 23.13.35.10.3-2.0-1.9-1.8-1.31.5-2.2-2.1-1.9-2.3
Rest time, locomotor task time 21.61.93.7-0.7-1.3-1.2-1.3-1.01.0-1.9-1.7-1.3-1.9
Distance moved, locomotor task time 20.60.71.60.50.70.60.90.1-0.81.20.90.61.3
Vertical activity count, locomotor time 20.50.61.90.70.20.10.8-0.9-0.91.00.40.11.4
Weight adjusted by age1.31.53.61.9-0.8-1.0-1.6-0.41.8-1.1-0.7-0.7-1.3
Seeking ratio, delayed vs. immediate footshock0.10.10.20.10.30.2-0.20.20.1-0.00.40.2-0.5
Locomotion in novel chamber0.50.71.00.5-0.5-0.2-1.0-0.71.0-1.0-0.9-0.7-1.0
Locomotion in novel chamber post-restriction0.20.30.9-0.70.00.1-0.6-0.10.6-0.8-0.4-0.1-0.9
Progressive ratio0.40.41.51.2-0.5-0.4-0.5-0.90.6-0.3-0.7-0.60.0
Food seeking constrained by brief footshock0.20.31.2-0.60.10.10.7-0.0-1.10.5-0.00.00.6
Seeking ratio, punishment vs. effort0.10.20.8-0.90.1-0.00.40.3-0.70.10.10.1-0.0
Run reversals in cocaine runway, females0.10.10.1-0.00.20.30.3-0.1-0.20.30.20.30.3
Run reversals in cocaine runway, males3.43.34.81.0-2.1-1.9-1.6-2.01.6-1.9-2.2-1.9-1.5
Latency to leave start box in cocaine runway1.11.21.9-0.51.11.11.01.2-0.81.21.41.21.1
Latency to leave start box in cocaine runway, F0.10.10.30.10.20.20.30.6-0.10.40.40.30.5
Latency to leave start box in cocaine runway, M1.91.82.90.01.41.51.21.2-1.11.71.71.51.5
Cd content in liver0.30.40.60.40.70.80.40.7-0.10.60.70.70.6
Co content in liver1.11.32.7-0.7-1.5-1.6-0.8-1.20.3-1.2-1.1-0.9-1.4
Cu content in liver0.80.91.80.7-0.7-1.0-1.2-0.01.3-1.1-0.7-0.6-1.3
Fe content in liver0.70.82.00.51.01.10.61.4-0.30.91.01.00.8
K content in liver0.40.41.2-0.9-0.1-0.20.80.2-1.10.60.40.50.8
Mg content in liver1.01.01.7-1.00.70.61.20.7-1.31.10.91.01.2
Mn content in liver1.11.32.3-1.50.90.41.30.7-1.51.21.21.21.0
Na content in liver6.87.29.73.0-2.7-2.6-2.8-2.13.1-2.6-2.7-2.6-2.3
Rb content in liver1.51.93.2-0.41.31.31.51.3-1.41.61.41.41.8
Se content in liver0.00.10.20.50.1-0.4-0.1-0.00.30.00.10.10.0
Sr content in liver1.91.83.70.11.61.61.11.9-0.51.31.41.51.3
Zn content in liver2.42.64.22.0-1.6-1.9-1.9-0.92.0-1.5-1.3-1.2-1.6