Hub : Genes

Tma7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000047225 0.36 0.13 0.0e+00 0.44 0.44 0.44 0.44 1.7e-53 2.8e-53 1.9e-53 2.0e-53
2 BLA gene expression ENSRNOG00000047225 0.35 0.22 1.2e-14 0.24 0.21 0.25 0.25 5.3e-13 2.2e-11 1.6e-13 9.4e-14
3 BLA mRNA stability ENSRNOG00000047225 0.04 0.04 8.7e-03 0.04 0.03 0.04 0.03 5.0e-03 1.3e-02 5.4e-03 1.2e-02
4 Brain gene expression ENSRNOG00000047225 0.27 0.11 0.0e+00 0.33 0.34 0.34 0.34 2.7e-31 7.0e-32 3.7e-32 4.1e-32
5 Brain isoform ratio ENSRNOT00000075819 0.03 0.02 5.7e-04 0.02 0.02 0.02 0.02 5.4e-03 3.6e-03 8.7e-03 7.5e-03
6 Brain isoform ratio ENSRNOT00000119465 0.03 0.03 4.3e-04 0.02 0.02 0.02 0.02 3.6e-03 2.5e-03 5.2e-03 5.8e-03
7 Eye isoform ratio ENSRNOT00000075819 0.33 0.19 7.4e-03 0.1 0.06 0.11 0.1 1.3e-02 3.8e-02 8.6e-03 1.4e-02
8 Eye isoform ratio ENSRNOT00000119465 0.36 0.19 4.4e-03 0.11 0.08 0.14 0.13 8.7e-03 2.3e-02 3.8e-03 5.2e-03
9 IL gene expression ENSRNOG00000047225 0.3 0.15 3.8e-05 0.17 0.14 0.18 0.17 7.1e-05 2.8e-04 4.1e-05 7.0e-05
10 LHb gene expression ENSRNOG00000047225 0.23 0.12 1.1e-04 0.13 0.14 0.15 0.13 4.7e-04 3.8e-04 1.7e-04 6.7e-04
11 Liver gene expression ENSRNOG00000047225 0.21 0.09 0.0e+00 0.28 0.28 0.28 0.28 2.0e-31 1.0e-30 2.3e-31 4.0e-31
12 NAcc gene expression ENSRNOG00000047225 0.22 0.1 0.0e+00 0.26 0.24 0.25 0.26 4.8e-19 4.3e-18 7.2e-19 1.7e-19
13 PL gene expression ENSRNOG00000047225 0.11 0.07 1.2e-08 0.11 0.08 0.1 0.11 2.1e-08 5.7e-07 1.0e-07 1.9e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.31.12.1-0.8-0.9-1.5-0.9-1.01.0-1.31.3-1.3-1.1-0.7-1.1-0.7
BMI without tail1.53.14.7-1.8-1.8-2.2-1.9-1.81.8-1.21.3-1.9-1.5-1.7-2.0-1.8
Body weight5.423.030.6-4.5-4.6-5.4-4.9-4.94.9-4.64.3-5.5-4.2-4.6-5.0-4.7
Epididymis fat weight0.20.41.0-0.3-0.4-0.8-0.7-0.60.6-1.01.0-0.8-0.4-0.4-0.5-0.5
Glucose0.30.40.9-0.6-0.6-0.8-0.6-0.80.80.5-0.5-0.2-0.9-0.6-0.7-0.5
Heart weight2.94.28.5-1.9-2.0-1.8-1.9-1.71.7-2.92.8-2.6-0.7-1.8-1.9-1.9
Left kidney weight0.72.14.8-1.3-1.3-1.9-1.5-1.81.70.0-0.1-1.2-2.2-1.3-1.6-1.4
Right kidney weight0.30.83.0-0.5-0.5-1.0-0.8-1.01.00.8-0.9-0.4-1.7-0.6-0.8-0.7
Tail length6.018.021.9-4.5-4.5-4.4-4.6-4.44.4-2.92.7-4.5-3.7-4.6-4.6-4.7
Length with tail8.029.536.1-5.5-5.5-5.8-5.8-5.65.7-4.34.0-6.0-4.8-5.7-5.7-5.8
Length without tail5.612.215.8-3.2-3.3-3.7-3.6-3.63.6-3.43.1-4.0-3.3-3.5-3.5-3.5
Liver weight, left0.20.41.1-0.6-0.5-0.2-0.3-0.40.41.0-1.00.2-0.9-0.4-0.4-0.4
Liver weight, right1.32.25.5-1.6-1.6-1.5-1.5-1.71.6-0.1-0.0-1.1-2.3-1.6-1.6-1.4
Parametrial fat weight1.02.02.6-1.4-1.4-1.6-1.5-1.61.6-0.40.4-1.4-1.6-1.5-1.6-1.5
Retroperitoneal fat weight0.31.11.8-0.9-0.9-1.1-1.2-1.31.3-0.20.0-1.0-1.3-1.1-1.2-1.2
Intraocular pressure0.91.22.8-1.7-1.5-0.8-1.2-1.11.1-0.20.2-0.8-1.0-1.3-1.2-1.2
Extensor digitorum longus weight0.10.50.80.80.70.70.80.9-0.9-0.30.40.50.80.80.80.9
Soleus weight3.49.812.7-3.2-3.2-3.4-3.3-3.23.2-2.82.6-3.6-2.4-3.2-3.3-3.2
Tibialis anterior weight0.00.10.70.1-0.0-0.2-0.1-0.00.0-0.80.8-0.4-0.0-0.1-0.1-0.1
Tibia length6.117.122.1-4.0-4.1-4.7-4.4-4.44.4-3.12.9-4.6-4.2-4.1-4.5-4.2
Number of licking bursts0.40.41.10.40.40.60.50.7-0.7-1.01.1-0.00.90.40.50.5
Food consumed during 24 hour testing period1.21.52.0-1.2-1.2-1.4-1.3-1.31.3-1.11.1-1.4-1.0-1.1-1.3-1.2
Times rat made contact with spout0.70.81.1-0.9-0.9-1.0-0.9-0.80.9-1.01.0-1.1-0.4-0.9-0.9-0.9
Mean time between licks in bursts1.31.82.21.51.41.41.41.4-1.40.7-0.71.41.41.51.41.5
Mean num. licks in bursts0.81.01.6-1.0-0.9-1.2-1.0-1.31.20.5-0.7-0.5-1.2-0.9-1.1-1.0
Std. dev. time between licks in bursts4.45.28.32.42.42.52.52.7-2.60.1-0.01.82.92.42.52.5
Water consumed over 24 hours0.20.31.5-0.0-0.1-0.1-0.10.1-0.1-1.21.2-0.60.6-0.0-0.1-0.0
Indifference point 0 sec1.32.15.2-1.4-1.3-1.4-1.6-1.61.60.3-0.3-1.0-2.3-1.7-1.5-1.6
Indifference point AUC0.20.20.7-0.4-0.4-0.3-0.2-0.40.40.8-0.80.2-0.9-0.2-0.3-0.2
Indifference point function ln k0.40.61.01.01.00.60.80.6-0.60.5-0.60.60.90.90.70.8
Indifference point function log k0.40.61.01.01.00.60.80.6-0.60.5-0.60.60.90.90.70.8
Delay discounting total patch changes 0 sec1.42.24.1-1.5-1.5-1.5-1.6-1.71.6-0.20.1-1.2-2.0-1.8-1.6-1.7
Delay discounting total patch changes 12 sec1.01.32.0-1.2-1.2-1.1-1.3-1.31.3-0.40.3-1.0-1.4-1.3-1.2-1.3
Delay discounting total patch changes 18 sec1.82.43.8-1.7-1.7-1.6-1.7-1.81.8-0.20.2-1.1-2.0-1.8-1.6-1.7
Delay discounting total patch changes 24 sec2.32.93.6-1.7-1.8-1.9-1.8-1.91.9-1.31.2-1.8-1.7-1.6-1.8-1.7
Delay discounting total patch changes 6 sec0.50.73.0-0.6-0.6-0.5-0.6-0.80.81.1-1.1-0.0-1.7-0.7-0.6-0.7
Delay discounting time to switch 0 sec0.20.31.40.40.30.50.30.6-0.5-0.80.9-0.11.20.40.40.3
Delay discounting water rate 0 sec0.10.20.3-0.5-0.5-0.4-0.5-0.50.5-0.30.2-0.4-0.4-0.5-0.5-0.4
Delay discounting water rate 12 sec0.10.20.2-0.4-0.4-0.5-0.4-0.40.4-0.40.4-0.5-0.2-0.3-0.5-0.3
Delay discounting water rate 18 sec0.10.20.8-0.1-0.1-0.1-0.10.1-0.1-0.80.9-0.60.70.1-0.1-0.0
Delay discounting water rate 24 sec0.60.91.1-1.0-1.0-0.9-0.9-0.90.9-1.01.0-1.0-0.6-1.0-0.9-0.8
Delay discounting water rate 6 sec0.10.20.4-0.6-0.5-0.6-0.4-0.60.6-0.1-0.1-0.3-0.3-0.3-0.6-0.3
Locomotor activity5.18.09.7-3.1-3.0-3.0-3.1-3.03.0-1.81.7-3.1-2.4-3.1-3.1-3.1
Locomotor testing distance4.37.18.5-2.8-2.8-2.8-2.9-2.82.8-1.51.5-2.8-2.6-2.9-2.9-2.9
Locomotor testing rearing0.10.10.2-0.5-0.4-0.2-0.4-0.30.3-0.20.3-0.3-0.1-0.4-0.4-0.4
Light reinforcement 10.61.21.8-1.1-1.1-1.0-1.2-1.11.1-0.80.8-1.2-0.8-1.3-1.2-1.2
Light reinforcement 20.20.31.40.40.40.40.30.2-0.31.2-1.20.60.30.40.20.3
Reaction time number correct0.71.02.31.11.11.01.00.9-0.90.4-0.50.91.51.01.11.0
Reaction time mean minus median0.10.20.5-0.5-0.5-0.5-0.4-0.40.4-0.10.2-0.4-0.7-0.3-0.5-0.4
Reaction time mean minus median AUC0.30.40.8-0.9-0.9-0.7-0.6-0.60.6-0.10.2-0.4-0.9-0.4-0.8-0.6
Reaction time num false alarms0.30.40.60.70.70.70.60.6-0.60.8-0.70.70.10.50.70.6
Reaction time num false alarms AUC0.10.20.70.40.40.30.30.2-0.20.8-0.80.4-0.40.20.30.2
Reaction time trials correct on left0.71.02.31.11.11.01.00.9-0.90.4-0.50.91.51.01.11.0
Reaction time trials on left0.71.02.41.11.11.11.01.0-1.00.4-0.50.91.51.01.11.0
Reaction time mean0.00.00.20.20.10.20.0-0.00.00.3-0.40.2-0.00.10.10.0
Reaction time mean AUC0.10.10.50.20.20.20.1-0.0-0.00.6-0.70.4-0.10.20.20.1
Median of all reaction times0.10.10.30.50.50.30.10.0-0.00.5-0.60.30.20.30.30.1
Reaction time omissions0.20.30.50.60.60.70.50.5-0.50.4-0.40.50.50.40.60.4
Reaction time false alarm rate0.10.10.6-0.00.0-0.0-0.0-0.00.00.4-0.40.1-0.8-0.10.0-0.1
Reaction time premature initiation rate2.02.74.6-1.3-1.4-2.0-1.8-1.81.8-0.90.9-1.7-2.1-1.6-1.6-1.8
Reaction time premature initiations0.71.01.8-0.6-0.6-1.3-1.1-1.11.2-0.60.6-1.2-1.3-0.9-0.9-1.1
Std. dev. reaction times0.10.10.4-0.3-0.3-0.3-0.3-0.40.40.4-0.4-0.0-0.7-0.2-0.3-0.3
Reaction time trials completed0.71.02.41.11.11.11.01.0-1.00.4-0.50.91.51.01.11.0
Reaction time trials AUC0.91.32.61.31.31.21.21.1-1.10.6-0.61.11.61.21.21.2
Social response proportion0.30.30.6-0.4-0.4-0.7-0.5-0.70.7-0.40.2-0.6-0.8-0.5-0.5-0.5
Social responses0.40.61.2-0.8-0.8-0.9-0.8-0.80.8-0.20.1-0.7-1.1-0.7-0.8-0.8
Social time0.40.50.90.80.80.70.60.9-0.8-0.60.7-0.11.00.60.70.6
Conditioned locomotion2.73.24.31.61.71.91.81.7-1.81.9-1.92.11.61.71.81.7
Cocaine response after cond. corrected0.91.04.0-0.7-0.8-0.4-0.7-0.30.3-2.02.0-1.20.6-0.7-0.6-0.7
Cocaine response after cond. not corrected2.22.44.8-1.5-1.6-1.4-1.5-1.21.3-2.22.2-1.9-0.5-1.5-1.5-1.4
Cocaine response before conditioning0.91.13.2-0.9-0.9-1.4-1.0-1.31.30.1-0.2-0.8-1.8-0.9-1.1-0.9
Saline control response1.41.83.9-1.5-1.4-1.3-1.3-1.61.60.5-0.7-0.7-2.0-1.4-1.4-1.4
Condit. Reinf. active minus inactive responses1.51.92.9-1.2-1.3-1.7-1.4-1.51.5-1.31.3-1.5-1.5-1.1-1.4-1.2
Condit. Reinf. active-inactive response ratio1.41.52.1-1.0-1.1-1.4-1.2-1.21.2-1.41.4-1.4-1.2-1.0-1.2-1.0
Condit. Reinf. active responses1.52.02.9-1.3-1.3-1.7-1.4-1.51.5-1.31.2-1.5-1.6-1.2-1.4-1.3
Condit. Reinf. inactive responses0.00.00.10.10.10.00.10.0-0.00.2-0.30.2-0.10.10.10.1
Condit. Reinf. lever presses1.92.64.4-1.3-1.4-2.0-1.5-1.71.7-1.51.5-1.7-2.1-1.3-1.6-1.4
Condit. Reinf. lever reinforcers received1.62.33.2-1.4-1.4-1.8-1.5-1.61.6-1.41.3-1.6-1.7-1.3-1.5-1.4
Pavlov. Cond. lever latency0.20.30.80.40.40.80.50.6-0.60.7-0.60.60.90.30.50.4
Pavlov. Cond. magazine entry latency0.10.20.30.50.50.30.40.4-0.4-0.20.20.20.50.60.40.5
Pavlov. Cond. change in total contacts1.82.63.3-1.5-1.5-1.8-1.6-1.61.6-1.71.7-1.8-1.5-1.4-1.6-1.5
Pavlov. Cond. index score0.10.10.6-0.0-0.1-0.3-0.2-0.10.2-0.80.8-0.4-0.20.1-0.2-0.0
Pavlov. Cond. latency score0.10.10.50.0-0.0-0.3-0.1-0.10.1-0.70.7-0.4-0.20.2-0.1-0.0
Pavlov. Cond. lever contacts0.70.92.0-0.8-0.9-1.2-1.0-1.11.1-0.70.6-0.9-1.4-0.7-1.0-0.9
Pavlov. Cond. magazine entry number0.40.40.7-0.8-0.7-0.6-0.7-0.70.70.0-0.1-0.5-0.7-0.9-0.7-0.8
Pavlov. Cond. intertrial magazine entries0.40.50.70.70.70.80.80.8-0.70.6-0.60.80.40.60.80.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.60.0-0.0-0.3-0.1-0.10.1-0.70.8-0.4-0.10.1-0.10.0
Pavlov. Cond. response bias0.00.10.20.10.0-0.3-0.0-0.10.1-0.50.5-0.2-0.30.2-0.10.1
Conditioned reinforcement - actives0.20.20.50.30.30.50.50.5-0.60.5-0.40.60.20.70.50.5
Conditioned reinforcement - inactives1.11.32.71.01.01.11.11.4-1.3-0.81.00.41.61.31.11.2
Conditioned locomotion0.40.41.60.30.40.40.50.4-0.41.3-1.20.9-0.00.60.40.4
Intermittent access intake day 1-15 change0.90.91.81.31.20.90.81.0-1.0-0.70.70.21.30.91.00.9
Intermittent access intake escalation0.80.81.71.31.20.90.81.0-0.9-0.40.50.21.30.81.00.8
Intermittent access intake escalation 20.40.41.40.90.80.20.20.3-0.3-1.21.1-0.50.90.20.50.2
Intermitt. access day 1 inactive lever presses0.00.00.1-0.1-0.1-0.2-0.1-0.10.1-0.20.2-0.0-0.3-0.0-0.10.0
Intermitt. access day 15 inactive lever presses0.50.61.01.00.90.70.71.0-0.9-0.40.60.30.70.70.90.8
Intermitt. access escalation Index0.10.10.4-0.1-0.1-0.1-0.0-0.10.10.6-0.60.3-0.5-0.2-0.1-0.1
Intermittent access day 1 total infusions0.00.00.1-0.1-0.1-0.0-0.10.1-0.10.2-0.10.1-0.30.00.0-0.1
Intermittent access day 15 total infusions0.30.40.90.90.90.50.50.7-0.70.10.00.30.60.60.70.5
Intermittent access terminal intake (last 3 days)0.10.20.50.70.60.30.30.4-0.40.3-0.20.30.20.30.50.3
Intermittent access total infusions0.30.40.60.80.80.50.50.7-0.70.5-0.30.50.40.60.70.5
Intermittent access day 1 locomotion0.10.10.30.10.10.20.20.3-0.30.5-0.40.5-0.30.30.20.2
Intermittent access day 15 total locomotion1.21.32.41.21.21.01.00.9-0.91.5-1.51.30.61.11.11.0
Intermittent access total locomotion1.31.52.71.31.31.11.11.0-1.01.6-1.61.50.51.21.21.1
Intermittent access standard deviation0.60.62.80.60.4-0.3-0.4-0.00.1-1.61.7-1.10.4-0.20.1-0.3
Cocaine induced anxiety0.10.10.5-0.1-0.10.10.10.4-0.4-0.40.7-0.20.10.00.10.0
Post-drug Anxiety0.00.10.2-0.3-0.30.10.10.3-0.3-0.30.5-0.00.10.00.00.1
Baseline Anxiety0.90.91.11.01.01.01.00.8-0.80.9-1.01.00.90.91.01.0
Lifetime Intake0.40.40.60.80.80.60.60.7-0.70.6-0.60.70.40.70.70.6
Incentive Sensitization - Responses1.11.11.61.21.11.11.11.3-1.30.3-0.10.91.11.21.21.1
Incentive Sensitization - Breakpoint1.01.11.61.21.11.01.11.3-1.20.2-0.10.81.11.21.21.0
Progressive ratio test 1 active lever presses0.10.10.70.10.10.00.0-0.00.00.8-0.70.4-0.60.10.00.0
Progressive ratio test 1 breakpoint0.20.20.70.10.10.10.10.0-0.10.9-0.80.6-0.80.20.10.2
Progressive ratio test 1 inactive lever presses0.30.30.50.50.40.60.60.7-0.7-0.40.60.40.30.70.60.7
Progressive ratio test 2 active lever presses0.70.71.01.01.00.70.80.9-0.90.8-0.70.90.50.90.90.8
Progressive ratio test 2 breakpoint0.40.40.70.80.80.60.60.7-0.70.5-0.40.60.40.70.80.6
Progressive ratio test 2 inactive lever presses1.31.52.51.41.31.11.21.6-1.5-0.40.70.61.41.31.41.2
Total sessions with >9 infusions0.30.30.80.20.20.40.40.6-0.5-0.80.9-0.10.80.50.30.4
Short access day 1 total inactive lever presses4.85.47.62.12.22.62.62.6-2.61.0-1.02.32.62.82.42.6
Short access day 10 total inactive lever presses0.50.63.7-0.2-0.3-0.2-0.20.2-0.1-1.81.9-0.80.2-0.2-0.1-0.1
Short access day 1 total infusions0.80.91.50.60.71.11.11.2-1.20.3-0.21.00.91.21.01.1
Short access day 10 total infusions0.20.20.40.60.50.30.30.3-0.30.6-0.70.40.10.40.40.3
Short access total infusions0.91.01.41.01.01.01.00.9-0.91.1-1.11.20.51.11.01.0
Short access day 1 locomotion0.00.00.10.10.10.00.20.2-0.20.1-0.00.20.10.30.20.2
Short access day 10 total locomotion0.10.10.70.10.1-0.1-0.1-0.20.20.8-0.80.4-0.50.1-0.0-0.0
Short access total locomotion0.20.20.8-0.2-0.1-0.1-0.0-0.20.10.9-0.80.5-0.90.1-0.00.0
Compulsive drug intake0.40.41.90.10.20.50.50.2-0.21.2-1.40.90.50.40.30.5
One hour access (0.3 mA shock)0.40.51.40.70.80.50.50.5-0.51.2-1.20.80.30.70.70.5
One hour access (shock baseline)0.00.00.20.40.3-0.1-0.10.2-0.2-0.00.2-0.1-0.20.00.2-0.1
Number of responses in last shaping day0.40.40.90.60.60.70.71.0-0.9-0.10.30.40.70.70.70.7
Context. condit. distance diff. score0.00.00.0-0.1-0.1-0.1-0.00.0-0.0-0.20.2-0.20.0-0.0-0.1-0.0
Locomotion velocity, session 10.10.10.40.30.30.10.20.1-0.20.6-0.60.4-0.10.20.20.2
Locomotion distance, session 10.70.92.5-0.8-0.8-1.3-1.0-1.21.10.1-0.1-0.8-1.6-0.8-1.0-0.9
Locomotion velocity, session 20.20.30.50.70.70.40.60.6-0.60.1-0.00.40.50.70.50.6
Locomotion distance, session 20.20.21.00.40.40.00.3-0.0-0.01.0-1.00.5-0.60.50.20.3
Locomotion velocity, session 30.30.42.20.00.1-0.5-0.1-0.40.41.0-1.00.2-1.50.0-0.2-0.0
Locomotion distance, session 31.41.52.61.41.40.91.21.0-1.01.6-1.61.40.21.41.21.3
Stereotopy head waving bouts, day 30.40.52.8-0.3-0.4-0.1-0.20.1-0.0-1.61.7-0.80.6-0.3-0.2-0.2
Stereotopy head waving duration, day 30.30.41.2-0.7-0.7-0.3-0.5-0.40.4-1.11.1-0.8-0.0-0.6-0.5-0.6
Locomotion velocity, session 70.30.31.4-0.1-0.1-0.3-0.1-0.40.41.1-1.20.3-0.9-0.1-0.2-0.2
Locomotion distance, session 71.31.73.11.31.31.11.31.0-1.11.8-1.71.60.41.41.21.2
Stereotopy head waving bouts, day 70.00.10.2-0.00.00.20.10.0-0.10.5-0.50.30.20.00.10.1
Stereotopy head waving duration, day 70.30.30.5-0.7-0.7-0.6-0.6-0.70.7-0.10.0-0.5-0.5-0.7-0.7-0.6
Locomotion velocity, session 80.20.31.3-0.2-0.3-0.7-0.3-0.60.50.4-0.4-0.2-1.1-0.1-0.4-0.2
Locomotion distance, session 80.40.51.9-0.3-0.3-0.7-0.4-0.70.71.1-1.2-0.0-1.4-0.2-0.6-0.3
Degree of sensitization distance1.01.01.5-1.2-1.2-0.9-1.1-1.01.0-0.70.7-1.0-0.6-1.1-1.1-1.1
Degree of sensitization stereotypy0.20.20.7-0.3-0.2-0.2-0.2-0.40.40.8-0.80.2-0.6-0.3-0.3-0.2
Condit. Reinf. active minus inactive responses0.10.10.5-0.0-0.0-0.2-0.1-0.10.1-0.70.7-0.3-0.0-0.0-0.0-0.1
Condit. Reinf. active-inactive response ratio0.30.31.5-0.3-0.3-0.4-0.3-0.30.3-1.21.2-0.7-0.2-0.3-0.2-0.4
Condit. Reinf. active responses0.10.10.60.10.00.20.10.2-0.2-0.50.5-0.10.70.10.10.0
Condit. Reinf. inactive responses0.40.51.60.50.50.80.60.7-0.70.7-0.60.71.30.60.60.6
Incentive salience index mean0.10.10.20.30.30.20.30.3-0.3-0.20.30.10.30.40.30.2
Condit. Reinf. lever presses1.11.52.01.31.31.31.31.4-1.40.8-0.71.21.31.41.21.2
Time in familiar zone, hab. session 11.31.33.40.90.91.51.11.4-1.40.1-0.00.91.81.11.21.0
Time in novel zone, hab. session 10.70.72.0-0.6-0.6-1.1-0.8-1.00.9-0.30.2-0.8-1.4-0.8-0.8-0.6
Total zone transitions, hab. session 10.50.72.9-0.5-0.5-1.0-0.7-1.01.00.5-0.6-0.5-1.7-0.5-0.8-0.6
Total locomotion distance, hab. session 10.20.31.1-0.6-0.6-0.7-0.5-0.70.70.1-0.1-0.4-1.1-0.3-0.6-0.5
Locomotion velocity, hab. session 10.30.41.3-0.6-0.6-0.8-0.6-0.80.70.3-0.4-0.3-1.1-0.4-0.7-0.5
Time in familiar zone, hab. session 20.80.82.60.70.71.00.91.0-1.0-0.40.50.51.60.90.80.8
Time in novel zone, hab. session 20.10.10.5-0.0-0.0-0.3-0.2-0.30.30.7-0.70.1-0.7-0.4-0.1-0.2
Total zone transitions, hab. session 20.10.10.40.10.1-0.4-0.1-0.30.20.2-0.1-0.2-0.60.1-0.2-0.1
Total locomotion distance, hab. session 20.30.40.7-0.7-0.7-0.8-0.6-0.70.7-0.00.0-0.5-0.8-0.5-0.8-0.6
Locomotion velocity, hab. session 20.20.30.9-0.6-0.6-0.7-0.5-0.70.60.1-0.1-0.4-0.9-0.4-0.7-0.5
Novel to familiar place preference ratio1.11.13.3-0.8-0.7-0.7-0.9-1.21.11.7-1.80.1-1.1-0.9-0.8-0.8
Novelty place preference1.21.23.9-0.8-0.7-0.7-0.9-1.21.21.8-2.00.2-1.2-1.0-0.8-0.9
Time in novel zone, NPP test1.21.32.8-0.9-0.8-0.8-1.0-1.31.31.5-1.7-0.0-1.2-1.1-1.0-1.0
Total zone transitions, NPP test1.92.76.8-1.4-1.4-2.1-1.6-2.01.90.1-0.2-1.3-2.6-1.4-1.8-1.6
Total locomotion distance, NPP test1.01.32.0-1.2-1.2-1.4-1.2-1.31.3-0.40.4-1.1-1.2-1.1-1.3-1.2
Locomotion velocity, NPP test1.01.42.2-1.2-1.2-1.5-1.3-1.41.4-0.20.2-1.1-1.3-1.1-1.4-1.2
Pavlov. Cond. lever latency4.35.57.4-2.5-2.5-2.4-2.6-2.62.6-1.21.0-2.2-2.5-2.7-2.5-2.5
Pavlov. Cond. magazine entry latency5.57.19.22.82.82.92.93.0-3.01.0-0.82.52.93.02.92.8
Pavlov. Cond. change in total contacts1.51.62.81.31.21.41.41.5-1.50.2-0.11.11.71.41.41.3
Pavlov. Cond. index score5.46.99.52.82.72.82.93.0-3.00.9-0.72.43.13.02.82.7
Pavlov. Cond. latency score5.36.88.82.82.82.82.92.9-2.91.2-0.92.42.83.02.82.7
Pavlov. Cond. lever contacts2.32.73.91.81.71.71.81.9-1.90.7-0.61.51.72.01.71.8
Pavlov. Cond. magazine entry number6.48.011.2-2.9-2.9-3.1-3.1-3.23.2-1.21.0-2.7-3.3-3.1-3.0-3.0
Pavlov. Cond. intertrial magazine entries0.20.30.4-0.6-0.6-0.5-0.7-0.60.6-0.10.1-0.5-0.3-0.6-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.4.86.19.22.62.52.62.72.9-2.80.5-0.32.13.02.82.62.6
Pavlov. Cond. response bias5.97.210.72.82.82.92.93.1-3.10.8-0.62.43.33.02.92.8
Bone: apparent density0.10.21.1-0.00.0-0.1-0.1-0.30.31.0-1.10.4-0.10.0-0.1-0.1
Bone surface0.10.10.20.50.50.30.30.3-0.30.5-0.40.30.50.40.30.3
Bone volume0.10.10.40.30.30.10.10.1-0.10.6-0.60.30.40.20.10.1
Bone: connectivity density0.50.83.60.50.60.60.50.3-0.31.8-1.91.10.00.50.50.5
Bone: cortical apparent density0.20.30.70.40.50.60.50.4-0.40.8-0.80.70.20.50.50.5
Bone: cortical area0.50.72.20.60.50.50.50.7-0.7-1.41.4-0.21.50.50.50.4
Bone: cortical porosity0.40.42.30.10.10.30.1-0.0-0.01.4-1.50.8-0.40.10.20.1
Bone: cortical porosity0.60.63.10.30.40.50.40.2-0.21.7-1.81.1-0.20.30.40.3
Bone: cortical thickness0.61.05.3-0.2-0.3-0.3-0.30.00.0-2.22.3-1.11.1-0.2-0.3-0.3
Bone: cortical thickness0.00.00.3-0.0-0.00.10.10.1-0.1-0.30.3-0.00.50.10.00.0
Bone: cortical tissue density0.30.30.90.40.50.60.60.4-0.40.9-0.90.70.10.60.50.5
Bone: elastic displacement0.20.21.1-0.1-0.2-0.2-0.2-0.10.1-1.01.0-0.50.6-0.1-0.1-0.2
Bone: elastic work0.50.72.1-0.5-0.6-0.8-0.7-0.50.6-1.51.4-1.10.4-0.5-0.7-0.6
Bone: endosteal estimation0.10.10.4-0.2-0.2-0.2-0.2-0.30.30.6-0.60.1-0.6-0.3-0.2-0.3
Bone: endosteal perimeter1.02.12.61.61.61.51.51.5-1.51.2-1.21.51.11.51.51.5
Bone: final force1.11.74.1-1.0-1.1-1.2-1.2-1.01.0-2.02.0-1.7-0.4-1.1-1.1-1.2
Bone: final moment1.42.25.3-1.1-1.2-1.4-1.4-1.11.2-2.32.3-1.9-0.4-1.2-1.3-1.4
Bone: marrow area0.10.10.4-0.3-0.2-0.2-0.3-0.40.30.6-0.60.0-0.6-0.3-0.3-0.3
Bone: maximum diameter0.40.71.80.80.80.80.71.0-0.9-0.70.80.21.30.70.80.8
Bone: maximum force0.71.11.9-0.9-1.0-1.0-1.1-0.91.0-1.41.4-1.4-0.3-1.0-1.0-1.1
Bone: maximum moment0.81.42.6-1.0-1.0-1.1-1.2-1.01.0-1.61.6-1.5-0.3-1.1-1.1-1.2
Bone: minimum diameter0.40.81.31.11.00.90.91.0-1.00.2-0.20.71.11.01.00.9
Bone: periosteal estimation0.00.00.20.10.1-0.0-0.00.1-0.1-0.40.4-0.20.30.00.0-0.0
Bone: periosteal perimeter1.01.72.51.51.51.41.41.5-1.50.4-0.31.11.61.41.41.4
Bone: post-yield work0.00.00.0-0.1-0.1-0.2-0.2-0.20.20.1-0.1-0.20.1-0.1-0.2-0.2
Bone: stiffness0.10.20.3-0.3-0.4-0.4-0.5-0.40.4-0.40.4-0.5-0.1-0.5-0.4-0.5
Bone: tissue strength2.82.74.5-1.5-1.5-1.6-1.6-1.41.5-2.12.1-2.0-1.0-1.6-1.5-1.6
Bone: trabecular number1.11.74.71.11.21.01.10.8-0.82.1-2.21.60.61.21.01.1
Bone: trabecular spacing1.92.55.9-1.4-1.5-1.3-1.4-1.11.1-2.42.4-1.9-0.6-1.4-1.3-1.5
Bone: trabecular thickness0.20.21.1-0.1-0.0-0.2-0.1-0.40.31.0-1.10.3-0.2-0.1-0.2-0.1
Bone: trabecular tissue density0.30.40.5-0.7-0.7-0.7-0.7-0.70.7-0.0-0.0-0.5-0.6-0.7-0.7-0.7
Breakpoint value in progressive ratio session0.10.20.4-0.6-0.6-0.4-0.4-0.40.4-0.10.2-0.1-0.2-0.4-0.4-0.4
Distance traveled before self-admin0.20.20.90.90.80.30.20.3-0.3-0.60.5-0.30.00.20.50.2
Distance traveled after self-admin0.50.51.91.41.30.50.60.7-0.60.2-0.20.3-0.10.70.90.5
Delta time in closed arm before/after self-admin0.50.52.90.00.10.70.70.5-0.50.4-0.50.91.70.50.40.8
Delta time in open arm before/after self-admin0.30.31.5-0.1-0.1-0.5-0.5-0.50.40.4-0.4-0.5-1.2-0.5-0.3-0.6
Diff in mean of infusions in LGA sessions0.70.83.9-0.6-0.7-0.1-0.20.1-0.1-1.82.0-0.71.0-0.1-0.3-0.2
Extinction: sum of active levers before priming0.10.10.2-0.1-0.1-0.1-0.3-0.20.20.4-0.30.2-0.3-0.3-0.1-0.3
Active lever presses in extinction session 60.30.30.7-0.1-0.1-0.7-0.6-0.70.70.7-0.7-0.1-0.9-0.4-0.4-0.6
Delta distance traveled before/after self-admin0.10.10.40.30.3-0.10.10.2-0.20.6-0.50.3-0.50.20.20.0
Delta ambulatory time before/after self-admin0.40.41.2-0.6-0.6-0.9-0.7-0.60.60.1-0.0-0.5-1.1-0.6-0.6-0.8
Time in closed arm before self-admin1.41.65.9-0.7-0.7-1.2-1.3-1.21.2-0.90.8-1.5-2.4-1.0-1.1-1.3
Time in closed arm after self-admin0.10.10.3-0.2-0.20.30.20.1-0.0-0.40.40.10.50.2-0.10.2
Time in open arm before self-admin0.80.82.20.80.80.91.01.0-1.00.5-0.41.01.50.70.91.0
Time in open arm after self-admin0.80.94.40.70.80.30.40.2-0.32.0-2.10.9-0.70.20.50.3
Sum of active levers in priming session hrs 5-60.50.51.2-0.4-0.5-0.9-0.9-0.90.9-0.10.1-0.7-1.1-0.8-0.7-0.9
Time to tail flick, vehicle, before self-admin1.81.82.4-1.6-1.6-1.2-1.4-1.41.4-1.00.9-1.3-1.5-1.4-1.4-1.3
Time to tail flick, vehicle, after self-admin1.31.42.8-0.8-0.8-1.0-1.1-0.80.9-1.51.6-1.7-1.4-1.0-1.0-1.1
Time to tail flick, test, before self-admin0.30.30.9-0.4-0.3-0.4-0.4-0.60.60.9-0.90.1-0.5-0.3-0.5-0.5
Time to tail flick, test, after self-admin0.10.10.40.20.10.0-0.00.2-0.2-0.50.6-0.3-0.20.20.20.0
Delta time to tail flick, vehicle, before/after SA0.30.30.60.80.70.50.40.7-0.7-0.50.6-0.00.50.60.60.4
Delta time to tail flick, test, before/after SA0.30.30.40.60.60.50.50.7-0.6-0.30.40.20.20.50.60.5
Ambulatory time before self-admin0.50.51.41.21.00.60.50.6-0.6-0.40.30.11.00.60.80.5
Ambulatory time after self-admin0.30.41.51.21.10.10.20.2-0.20.6-0.60.2-0.90.30.60.1
Total heroin consumption1.21.42.4-1.0-1.0-1.4-1.2-1.01.0-1.41.4-1.6-0.6-1.1-1.1-1.3
Area under the delay curve1.81.93.21.21.31.21.41.3-1.31.8-1.71.70.61.41.31.4
Delay disc. indifference point, 0s delay0.00.00.1-0.2-0.10.20.10.1-0.10.2-0.20.2-0.00.1-0.00.2
Delay disc. indifference point, 16s delay0.90.91.70.80.90.90.90.8-0.81.3-1.21.20.70.80.90.8
Delay disc. indifference point, 2s delay0.20.20.40.50.50.30.40.4-0.40.6-0.50.5-0.00.50.40.5
Delay disc. indifference point, 24s delay0.90.91.51.01.00.80.80.8-0.81.2-1.21.10.50.90.90.8
Delay disc. indifference point, 4s delay1.31.41.81.11.11.21.21.3-1.31.1-1.01.40.61.21.21.3
Delay disc. indifference point, 8s delay2.02.13.51.41.51.31.41.3-1.31.9-1.81.70.61.51.41.4
Delay discount exponential model param2.02.13.1-1.3-1.4-1.4-1.5-1.41.4-1.71.6-1.8-0.7-1.5-1.4-1.5
Delay discount hyperbolic model param1.92.13.1-1.3-1.3-1.3-1.4-1.41.4-1.81.6-1.8-0.7-1.5-1.4-1.5
Fecal boli incidents, locomotor time 10.70.81.2-1.0-1.0-0.6-1.0-0.70.7-0.91.0-1.0-0.2-1.1-0.9-1.1
Change in fecal boli incidents, locomotor task0.10.10.20.00.0-0.20.3-0.00.00.3-0.40.4-0.40.40.10.5
Time >=10cm from walls, locomotor time 10.60.61.50.90.90.60.70.4-0.41.1-1.21.00.80.60.70.6
Bouts of movement, locomotor time 10.10.10.3-0.5-0.5-0.3-0.4-0.20.2-0.50.5-0.4-0.1-0.4-0.4-0.4
Total resting periods, locomotor time 10.10.10.4-0.4-0.4-0.2-0.3-0.20.2-0.50.6-0.30.1-0.3-0.3-0.3
Rest time, locomotor task time 10.40.51.50.50.40.90.60.8-0.80.5-0.30.81.20.60.60.6
Distance moved, locomotor task time 11.21.32.1-1.0-1.0-1.3-1.1-1.21.2-1.31.1-1.5-1.0-1.1-1.1-1.1
Vertical activity count, locomotor time 10.80.91.4-0.9-0.9-1.0-1.0-1.01.0-0.70.6-1.0-0.6-1.2-0.9-1.1
Time >=10cm from walls, locomotor time 21.11.11.7-1.0-1.1-1.0-1.2-1.21.2-0.70.6-1.1-0.6-1.2-1.2-1.3
Bouts of movement, locomotor time 20.10.20.50.30.30.10.20.3-0.3-0.40.5-0.2-0.70.50.30.5
Total resting periods, locomotor time 20.20.30.60.50.50.40.50.5-0.5-0.10.30.1-0.50.80.50.8
Rest time, locomotor task time 20.10.10.2-0.4-0.30.20.10.2-0.20.2-0.10.40.5-0.0-0.00.0
Distance moved, locomotor task time 20.80.92.0-0.4-0.5-1.0-0.9-1.01.0-1.20.9-1.4-1.0-0.7-0.8-0.8
Vertical activity count, locomotor time 20.00.10.10.20.2-0.2-0.2-0.30.3-0.1-0.0-0.4-0.3-0.3-0.1-0.2
Weight adjusted by age0.60.71.7-0.4-0.5-0.9-0.8-0.50.5-1.21.3-1.2-0.3-0.8-0.5-0.8
Seeking ratio, delayed vs. immediate footshock2.12.43.11.51.51.51.41.5-1.61.7-1.51.81.71.31.51.4
Locomotion in novel chamber0.20.21.00.50.50.30.30.4-0.4-0.20.2-0.11.00.40.40.3
Locomotion in novel chamber post-restriction0.40.50.9-0.6-0.6-0.8-0.8-1.01.00.1-0.3-0.6-0.3-0.7-0.8-0.8
Progressive ratio3.03.54.9-1.8-1.8-2.1-2.2-2.22.2-0.80.7-1.9-1.4-2.2-2.0-2.2
Food seeking constrained by brief footshock1.01.22.21.51.41.11.21.0-1.00.6-0.70.91.21.11.21.2
Seeking ratio, punishment vs. effort5.06.18.12.62.62.72.82.7-2.71.0-1.02.42.32.82.72.8
Run reversals in cocaine runway, females2.52.54.61.61.61.71.81.6-1.60.5-0.61.42.21.81.61.8
Run reversals in cocaine runway, males1.21.12.2-0.7-0.8-1.1-1.1-0.80.8-1.41.5-1.3-0.9-1.2-0.9-1.1
Latency to leave start box in cocaine runway0.70.81.3-1.1-1.1-0.8-0.9-0.80.8-0.90.9-0.9-0.5-1.0-0.9-0.8
Latency to leave start box in cocaine runway, F1.82.03.8-1.4-1.4-1.2-1.3-1.11.1-2.01.9-1.7-0.6-1.2-1.3-1.2
Latency to leave start box in cocaine runway, M0.20.21.10.10.20.20.20.2-0.21.0-0.90.6-0.1-0.10.30.2
Cd content in liver2.52.83.8-1.8-1.8-1.4-1.7-1.51.5-1.91.9-1.9-0.6-1.8-1.6-1.8
Co content in liver0.10.10.40.30.30.10.20.3-0.3-0.60.6-0.10.30.20.30.2
Cu content in liver3.84.66.2-2.5-2.5-2.2-2.4-2.32.3-1.11.0-2.0-1.9-2.4-2.3-2.4
Fe content in liver1.82.23.0-1.7-1.7-1.1-1.5-1.31.3-1.61.6-1.6-0.7-1.6-1.4-1.6
K content in liver1.01.01.4-1.1-1.1-1.0-1.1-1.01.0-0.40.4-1.0-1.0-1.0-1.2-1.0
Mg content in liver0.00.00.0-0.1-0.1-0.2-0.1-0.10.10.2-0.1-0.1-0.1-0.0-0.2-0.0
Mn content in liver0.60.62.5-0.5-0.5-1.0-0.6-0.90.90.6-0.7-0.3-1.6-0.5-0.7-0.6
Na content in liver0.40.40.9-0.8-0.8-0.5-0.7-0.70.70.2-0.2-0.4-1.0-0.8-0.7-0.8
Rb content in liver1.01.32.5-1.3-1.3-0.6-1.1-0.80.8-1.61.6-1.2-0.3-1.3-0.9-1.3
Se content in liver0.10.10.2-0.4-0.4-0.1-0.4-0.30.3-0.30.3-0.40.4-0.3-0.5-0.4
Sr content in liver0.00.00.10.10.1-0.3-0.0-0.10.10.2-0.2-0.0-0.10.1-0.10.1
Zn content in liver4.34.75.7-2.4-2.4-2.2-2.4-2.32.3-1.31.2-2.2-1.9-2.3-2.4-2.3