Hub : Genes

Rnf8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000047171 0.5 0.15 0.0e+00 0.54 0.55 0.55 0.55 2.2e-71 9.4e-73 2.2e-73 5.2e-73
2 Adipose mRNA stability ENSRNOG00000047171 0.04 0.04 2.5e-05 0.03 0.03 0.02 0.02 1.8e-04 7.7e-04 1.4e-03 1.4e-03
3 BLA gene expression ENSRNOG00000047171 0.06 0.04 5.9e-04 0.03 0.03 0 0.02 7.7e-03 1.3e-02 2.1e-01 4.1e-02
4 Brain gene expression ENSRNOG00000047171 0.11 0.07 1.6e-11 0.11 0.11 0.11 0.11 2.6e-10 1.5e-10 1.2e-10 9.8e-11
5 Liver alternative polyA ENSRNOT00000065629 0.05 0.05 3.7e-06 0.04 0.04 0.04 0.04 1.1e-05 1.1e-05 2.4e-05 1.4e-05
6 Liver alternative polyA ENSRNOT00000081715 0.05 0.05 7.4e-06 0.04 0.04 0.04 0.04 1.8e-05 2.0e-05 1.7e-05 2.9e-05
7 Liver gene expression ENSRNOG00000047171 0.93 0.03 0.0e+00 0.64 0.63 0.63 0.63 1.1e-92 5.4e-91 4.7e-90 2.9e-91
8 NAcc gene expression ENSRNOG00000047171 0.16 0.1 1.2e-04 0.04 0.04 0.03 0.03 1.1e-03 4.0e-04 1.6e-03 3.6e-03
9 PL gene expression ENSRNOG00000047171 0.05 0.04 1.2e-03 0.03 0.03 0.02 0.03 3.5e-03 4.7e-03 7.0e-03 3.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail2.89.111.23.13.03.12.53.1-2.93.03.43.1
BMI without tail1.73.64.21.91.91.91.61.9-1.91.92.11.8
Body weight6.728.230.65.55.35.55.15.0-5.35.35.15.5
Epididymis fat weight1.94.35.52.22.22.41.91.6-2.02.32.02.2
Glucose0.30.51.30.60.70.70.00.7-0.50.81.10.8
Heart weight1.52.23.9-1.5-1.6-1.5-2.0-1.11.5-1.7-0.9-1.2
Left kidney weight2.57.38.42.82.62.82.82.5-2.72.62.52.9
Right kidney weight3.29.011.23.12.93.03.32.8-3.12.82.63.2
Tail length0.92.83.51.61.61.71.81.7-1.91.71.41.5
Length with tail1.86.78.42.72.52.72.92.3-2.72.62.12.7
Length without tail1.53.24.21.91.81.82.01.4-1.81.81.52.1
Liver weight, left3.35.310.02.42.22.23.22.1-2.52.21.62.1
Liver weight, right2.03.35.21.71.61.72.32.2-2.11.61.61.5
Parametrial fat weight0.71.54.51.30.91.12.10.7-1.30.90.21.3
Retroperitoneal fat weight1.75.56.52.42.32.52.32.0-2.32.42.32.6
Intraocular pressure0.70.91.61.20.90.81.20.6-0.90.90.51.2
Extensor digitorum longus weight0.20.91.2-1.0-0.9-0.8-0.8-1.11.0-0.8-0.9-0.9
Soleus weight0.82.44.11.41.61.60.91.6-1.41.62.01.6
Tibialis anterior weight0.72.33.4-1.5-1.4-1.3-1.7-1.91.8-1.4-1.3-1.4
Tibia length2.15.86.82.42.42.42.62.4-2.62.42.02.4
Number of licking bursts0.50.60.7-0.8-0.8-0.8-0.8-0.60.7-0.8-0.6-0.8
Food consumed during 24 hour testing period0.80.91.11.01.11.00.60.8-0.91.01.01.0
Times rat made contact with spout4.34.95.9-2.2-2.3-2.2-1.8-2.22.1-2.2-2.4-2.2
Mean time between licks in bursts0.60.81.2-0.9-0.9-0.9-1.1-0.80.9-0.9-0.8-0.9
Mean num. licks in bursts0.50.60.9-0.7-0.8-0.7-0.4-0.90.7-0.7-0.9-0.7
Std. dev. time between licks in bursts1.82.14.01.41.61.60.51.2-1.01.62.01.6
Water consumed over 24 hours0.81.01.9-1.0-0.9-0.9-1.4-1.01.1-0.9-0.7-0.8
Indifference point 0 sec0.40.60.80.70.70.70.80.9-0.80.70.80.7
Indifference point AUC0.10.10.3-0.2-0.3-0.2-0.1-0.60.3-0.2-0.5-0.3
Indifference point function ln k0.10.10.3-0.3-0.2-0.3-0.50.30.1-0.30.2-0.3
Indifference point function log k0.10.10.3-0.3-0.2-0.3-0.50.30.1-0.30.2-0.3
Delay discounting total patch changes 0 sec0.40.60.90.60.70.70.71.0-0.80.70.80.7
Delay discounting total patch changes 12 sec0.00.00.10.10.10.20.1-0.30.10.2-0.10.1
Delay discounting total patch changes 18 sec0.30.41.40.60.50.61.20.5-0.70.60.30.5
Delay discounting total patch changes 24 sec0.10.20.4-0.4-0.4-0.3-0.6-0.30.5-0.3-0.2-0.3
Delay discounting total patch changes 6 sec0.10.10.20.30.20.40.30.2-0.30.30.20.4
Delay discounting time to switch 0 sec1.31.92.71.61.51.61.40.8-1.11.61.11.5
Delay discounting water rate 0 sec0.10.20.4-0.5-0.4-0.4-0.60.60.0-0.30.5-0.4
Delay discounting water rate 12 sec0.10.20.4-0.6-0.6-0.5-0.5-0.10.3-0.5-0.2-0.6
Delay discounting water rate 18 sec0.91.21.7-1.2-1.2-1.3-0.9-0.91.0-1.1-1.1-1.1
Delay discounting water rate 24 sec0.30.40.7-0.7-0.8-0.8-0.8-0.30.6-0.7-0.3-0.7
Delay discounting water rate 6 sec0.10.10.3-0.5-0.4-0.4-0.50.20.0-0.20.1-0.6
Locomotor activity0.10.20.40.30.30.20.60.6-0.50.10.4-0.1
Locomotor testing distance0.20.20.80.30.40.40.20.8-0.50.40.90.1
Locomotor testing rearing1.11.72.41.21.21.21.41.5-1.41.31.41.0
Light reinforcement 12.34.24.72.02.12.12.12.0-2.12.22.01.9
Light reinforcement 22.33.13.71.81.71.71.91.8-1.71.71.71.8
Reaction time number correct0.20.20.90.50.20.31.00.0-0.50.3-0.40.6
Reaction time mean minus median0.30.41.5-0.3-0.5-0.50.3-0.80.4-0.5-1.2-0.6
Reaction time mean minus median AUC0.20.20.8-0.1-0.3-0.30.4-0.60.3-0.2-0.9-0.4
Reaction time num false alarms0.20.20.3-0.5-0.5-0.6-0.1-0.40.5-0.5-0.6-0.3
Reaction time num false alarms AUC0.50.71.0-1.0-0.9-1.0-0.7-0.60.9-1.0-0.8-0.7
Reaction time trials correct on left0.20.20.90.50.20.31.00.0-0.50.3-0.40.6
Reaction time trials on left0.20.20.90.50.20.20.9-0.0-0.50.2-0.40.6
Reaction time mean0.10.10.20.40.40.40.5-0.1-0.20.40.00.1
Reaction time mean AUC0.20.30.70.60.60.60.80.1-0.40.60.00.3
Median of all reaction times0.30.40.60.70.80.70.60.3-0.50.70.50.4
Reaction time omissions0.40.51.5-0.5-0.7-0.70.0-1.00.6-0.6-1.2-0.6
Reaction time false alarm rate0.60.91.6-1.1-0.9-1.0-1.3-0.61.1-1.0-0.4-0.9
Reaction time premature initiation rate0.00.10.2-0.3-0.1-0.1-0.4-0.30.4-0.20.0-0.1
Reaction time premature initiations0.00.00.10.10.10.20.3-0.2-0.00.1-0.10.4
Std. dev. reaction times0.20.20.7-0.3-0.4-0.40.1-0.70.4-0.4-0.8-0.6
Reaction time trials completed0.20.20.90.50.20.20.9-0.0-0.50.2-0.40.6
Reaction time trials AUC0.10.20.80.50.10.20.90.0-0.50.2-0.40.6
Social response proportion0.70.72.40.50.50.50.11.5-0.70.41.50.7
Social responses0.20.20.70.20.40.4-0.20.6-0.10.30.90.4
Social time0.30.40.8-0.6-0.5-0.6-0.4-0.70.7-0.7-0.9-0.6
Conditioned locomotion2.02.43.71.61.51.51.91.4-1.71.51.21.5
Cocaine response after cond. corrected2.12.43.81.51.71.70.81.3-1.21.72.01.7
Cocaine response after cond. not corrected1.71.92.71.41.61.60.81.1-1.01.61.61.6
Cocaine response before conditioning0.20.30.8-0.3-0.5-0.50.2-0.60.3-0.5-0.9-0.4
Saline control response0.50.61.20.90.90.81.10.4-0.80.80.50.8
Condit. Reinf. active minus inactive responses1.21.53.6-1.0-1.0-0.9-1.1-1.91.3-0.9-1.6-0.9
Condit. Reinf. active-inactive response ratio0.40.41.4-0.5-0.3-0.3-0.8-1.20.7-0.3-0.8-0.3
Condit. Reinf. active responses1.21.63.5-1.0-1.1-1.1-1.0-1.91.4-1.1-1.7-1.0
Condit. Reinf. inactive responses0.10.10.3-0.0-0.2-0.20.3-0.40.2-0.2-0.6-0.2
Condit. Reinf. lever presses4.35.98.4-2.2-2.3-2.3-2.1-2.92.6-2.3-2.7-2.3
Condit. Reinf. lever reinforcers received2.02.95.3-1.5-1.5-1.5-1.4-2.31.8-1.5-2.1-1.4
Pavlov. Cond. lever latency2.83.84.91.81.92.01.52.2-2.02.02.22.0
Pavlov. Cond. magazine entry latency0.10.10.30.20.00.00.5-0.3-0.00.0-0.40.2
Pavlov. Cond. change in total contacts2.02.84.0-1.5-1.6-1.6-1.3-2.01.7-1.6-2.0-1.6
Pavlov. Cond. index score1.21.52.7-1.0-1.2-1.2-0.7-1.61.2-1.2-1.6-1.1
Pavlov. Cond. latency score0.81.01.9-0.8-1.0-0.9-0.5-1.31.0-0.9-1.4-0.9
Pavlov. Cond. lever contacts2.53.55.3-1.7-1.8-1.9-1.1-2.21.8-1.9-2.3-1.9
Pavlov. Cond. magazine entry number0.10.10.30.00.20.2-0.30.3-0.10.20.50.1
Pavlov. Cond. intertrial magazine entries0.60.71.2-0.9-0.9-0.8-1.1-0.60.8-0.8-0.6-1.0
Pavlov. Cond. lever-magazine prob. diff.0.81.02.0-0.8-1.0-1.0-0.4-1.31.0-1.0-1.4-0.9
Pavlov. Cond. response bias1.82.54.5-1.3-1.5-1.6-0.8-1.91.5-1.6-2.1-1.5
Conditioned reinforcement - actives0.70.71.20.90.90.90.80.3-0.70.90.51.1
Conditioned reinforcement - inactives0.40.40.9-0.6-0.6-0.6-0.2-0.80.6-0.6-0.9-0.5
Conditioned locomotion0.80.91.70.90.90.90.90.9-0.90.90.91.3
Intermittent access intake day 1-15 change0.20.21.00.2-0.0-0.01.0-0.2-0.3-0.0-0.70.4
Intermittent access intake escalation0.30.31.50.50.20.21.2-0.1-0.50.2-0.60.6
Intermittent access intake escalation 20.80.82.1-0.8-0.9-0.9-0.1-1.00.7-0.9-1.4-0.7
Intermitt. access day 1 inactive lever presses0.20.20.70.30.50.5-0.20.4-0.20.50.90.4
Intermitt. access day 15 inactive lever presses0.40.51.70.70.60.61.30.0-0.70.6-0.20.7
Intermitt. access escalation Index0.40.30.6-0.6-0.6-0.6-0.7-0.40.5-0.6-0.4-0.8
Intermittent access day 1 total infusions0.40.40.6-0.6-0.6-0.6-0.5-0.70.7-0.6-0.8-0.7
Intermittent access day 15 total infusions0.10.10.3-0.0-0.1-0.10.4-0.30.1-0.1-0.60.1
Intermittent access terminal intake (last 3 days)0.10.10.30.30.30.30.50.2-0.30.30.10.5
Intermittent access total infusions0.10.10.3-0.4-0.4-0.4-0.1-0.40.3-0.4-0.6-0.3
Intermittent access day 1 locomotion0.20.20.40.40.50.50.50.4-0.40.50.40.6
Intermittent access day 15 total locomotion2.52.76.41.71.51.52.50.9-1.71.50.52.0
Intermittent access total locomotion0.80.92.80.90.70.71.70.4-0.90.7-0.01.2
Intermittent access standard deviation1.01.01.31.01.11.11.00.8-1.01.10.91.1
Cocaine induced anxiety0.50.51.0-0.7-0.8-0.8-0.1-0.60.5-0.8-1.0-0.7
Post-drug Anxiety0.70.71.2-0.8-0.9-0.9-0.5-1.00.8-0.9-1.1-0.8
Baseline Anxiety0.10.10.50.10.30.3-0.60.10.10.30.70.2
Lifetime Intake0.00.00.10.20.20.20.30.1-0.20.20.00.3
Incentive Sensitization - Responses2.02.03.4-1.3-1.3-1.3-1.0-1.81.3-1.3-1.9-1.4
Incentive Sensitization - Breakpoint1.51.53.1-1.1-1.1-1.1-0.7-1.61.1-1.1-1.8-1.3
Progressive ratio test 1 active lever presses0.00.00.10.10.20.2-0.0-0.20.10.20.10.2
Progressive ratio test 1 breakpoint0.10.10.10.20.40.4-0.10.0-0.00.40.40.3
Progressive ratio test 1 inactive lever presses0.70.71.50.90.90.91.10.2-0.70.90.21.2
Progressive ratio test 2 active lever presses0.20.20.8-0.1-0.1-0.10.0-0.90.3-0.1-0.8-0.1
Progressive ratio test 2 breakpoint0.20.20.7-0.3-0.2-0.2-0.1-0.80.4-0.2-0.8-0.3
Progressive ratio test 2 inactive lever presses0.80.92.2-0.9-0.9-0.9-0.4-1.30.9-0.9-1.5-0.7
Total sessions with >9 infusions0.20.20.40.40.50.50.20.2-0.20.50.50.6
Short access day 1 total inactive lever presses0.10.10.2-0.3-0.2-0.2-0.3-0.40.3-0.2-0.3-0.3
Short access day 10 total inactive lever presses0.00.00.10.00.00.00.3-0.2-0.00.0-0.2-0.2
Short access day 1 total infusions0.50.50.9-0.8-0.6-0.6-0.9-0.70.8-0.6-0.4-0.8
Short access day 10 total infusions0.00.00.0-0.1-0.1-0.1-0.00.10.1-0.10.00.2
Short access total infusions0.10.10.20.30.40.40.10.3-0.20.40.50.4
Short access day 1 locomotion0.20.20.40.40.60.6-0.10.1-0.10.60.60.6
Short access day 10 total locomotion0.40.41.40.20.60.6-0.60.5-0.10.61.20.6
Short access total locomotion0.90.92.00.71.01.00.10.9-0.61.01.41.1
Compulsive drug intake0.90.93.3-1.0-0.7-0.7-1.8-0.61.1-0.7-0.0-0.8
One hour access (0.3 mA shock)1.21.42.3-1.1-1.1-1.1-1.0-1.51.3-1.1-1.5-1.0
One hour access (shock baseline)0.30.41.6-0.2-0.5-0.50.6-0.70.2-0.5-1.3-0.2
Number of responses in last shaping day0.50.52.00.20.60.6-1.00.5-0.00.61.40.7
Context. condit. distance diff. score0.20.20.5-0.3-0.2-0.3-0.5-0.70.5-0.4-0.4-0.4
Locomotion velocity, session 11.31.43.1-1.0-1.0-1.0-0.8-1.71.3-1.0-1.6-1.0
Locomotion distance, session 13.34.24.7-2.1-2.0-2.0-2.1-2.02.2-2.0-1.9-2.2
Locomotion velocity, session 20.20.30.4-0.6-0.5-0.5-0.6-0.40.5-0.5-0.4-0.6
Locomotion distance, session 20.60.91.1-1.0-0.9-0.9-1.0-0.91.0-0.9-0.8-1.1
Locomotion velocity, session 30.10.10.50.30.20.20.7-0.2-0.30.1-0.50.1
Locomotion distance, session 30.60.61.2-0.8-0.7-0.8-0.4-0.90.8-0.8-1.1-0.8
Stereotopy head waving bouts, day 31.62.02.61.51.61.51.61.0-1.41.51.11.4
Stereotopy head waving duration, day 30.40.40.70.70.80.70.30.6-0.60.70.90.6
Locomotion velocity, session 70.20.20.5-0.5-0.6-0.60.00.00.2-0.7-0.5-0.7
Locomotion distance, session 71.21.52.2-1.4-1.5-1.4-0.8-0.71.1-1.5-1.1-1.4
Stereotopy head waving bouts, day 70.20.20.40.60.50.40.60.1-0.50.4-0.00.4
Stereotopy head waving duration, day 70.70.91.21.11.00.91.10.8-1.10.90.50.8
Locomotion velocity, session 80.00.00.1-0.00.1-0.00.2-0.40.2-0.1-0.2-0.1
Locomotion distance, session 80.60.81.1-0.9-0.8-0.9-1.1-0.91.0-0.9-0.7-1.0
Degree of sensitization distance0.10.10.50.10.10.20.00.7-0.30.10.70.2
Degree of sensitization stereotypy0.20.20.7-0.2-0.4-0.5-0.1-0.50.2-0.5-0.8-0.5
Condit. Reinf. active minus inactive responses1.31.41.8-1.1-1.2-1.2-1.2-1.31.2-1.2-1.4-1.1
Condit. Reinf. active-inactive response ratio0.10.10.2-0.2-0.3-0.3-0.4-0.40.3-0.3-0.4-0.2
Condit. Reinf. active responses0.70.91.8-0.8-0.9-1.0-0.6-1.10.8-0.9-1.3-0.8
Condit. Reinf. inactive responses0.91.12.1-0.9-1.0-1.1-0.5-1.10.9-1.1-1.4-1.0
Incentive salience index mean0.60.70.9-0.7-0.8-0.9-0.8-0.90.7-0.8-0.9-0.7
Condit. Reinf. lever presses0.00.00.1-0.1-0.2-0.3-0.4-0.10.2-0.2-0.1-0.1
Time in familiar zone, hab. session 10.20.20.5-0.1-0.3-0.30.1-0.70.4-0.3-0.7-0.1
Time in novel zone, hab. session 10.70.71.30.60.70.70.51.1-0.80.71.20.6
Total zone transitions, hab. session 12.84.04.4-2.1-1.8-2.0-1.8-2.12.0-2.0-2.1-2.1
Total locomotion distance, hab. session 11.92.73.5-1.6-1.5-1.6-1.5-1.91.7-1.6-1.7-1.7
Locomotion velocity, hab. session 11.62.33.1-1.5-1.3-1.4-1.5-1.81.6-1.4-1.5-1.5
Time in familiar zone, hab. session 21.11.11.6-1.2-1.1-1.2-1.1-0.71.0-1.1-0.8-1.3
Time in novel zone, hab. session 20.90.91.31.11.01.11.20.4-0.91.10.41.0
Total zone transitions, hab. session 20.20.30.5-0.6-0.5-0.6-0.6-0.30.5-0.6-0.3-0.7
Total locomotion distance, hab. session 21.92.63.2-1.7-1.6-1.7-1.7-1.41.6-1.6-1.3-1.8
Locomotion velocity, hab. session 22.33.13.9-1.9-1.7-1.8-1.9-1.51.8-1.8-1.3-2.0
Novel to familiar place preference ratio0.70.70.90.90.91.00.40.6-0.71.00.90.9
Novelty place preference0.50.50.70.80.80.90.40.5-0.70.90.80.8
Time in novel zone, NPP test0.50.50.80.80.80.90.40.3-0.60.90.60.9
Total zone transitions, NPP test1.11.62.1-1.4-1.2-1.3-1.4-1.01.3-1.3-0.8-1.4
Total locomotion distance, NPP test0.81.11.6-1.1-1.0-1.1-1.3-0.81.1-1.1-0.6-1.2
Locomotion velocity, NPP test1.21.72.5-1.5-1.3-1.4-1.6-0.81.3-1.3-0.6-1.5
Pavlov. Cond. lever latency0.20.30.70.60.60.60.90.2-0.40.60.20.6
Pavlov. Cond. magazine entry latency0.30.40.5-0.6-0.7-0.7-0.7-0.50.7-0.7-0.4-0.6
Pavlov. Cond. change in total contacts0.20.20.50.70.50.50.60.2-0.50.50.10.7
Pavlov. Cond. index score0.10.10.2-0.2-0.3-0.3-0.50.00.2-0.30.2-0.2
Pavlov. Cond. latency score0.00.10.20.0-0.1-0.1-0.40.30.0-0.10.5-0.0
Pavlov. Cond. lever contacts0.10.20.5-0.4-0.5-0.4-0.7-0.20.4-0.4-0.1-0.4
Pavlov. Cond. magazine entry number0.60.81.40.90.90.91.20.8-1.00.90.60.8
Pavlov. Cond. intertrial magazine entries0.20.20.8-0.4-0.4-0.4-0.1-0.80.4-0.4-0.9-0.4
Pavlov. Cond. lever-magazine prob. diff.0.00.00.2-0.1-0.3-0.2-0.40.00.2-0.20.2-0.1
Pavlov. Cond. response bias1.01.21.5-1.0-1.1-1.1-1.2-1.21.2-1.1-1.0-1.0
Bone: apparent density1.01.61.9-1.3-1.4-1.4-1.0-1.01.1-1.3-1.4-1.3
Bone surface0.00.00.1-0.0-0.0-0.0-0.20.2-0.00.00.1-0.0
Bone volume0.00.00.0-0.1-0.2-0.2-0.00.2-0.1-0.1-0.1-0.1
Bone: connectivity density0.71.11.3-1.0-1.1-1.1-1.0-0.90.9-1.1-1.1-1.1
Bone: cortical apparent density0.10.10.2-0.3-0.4-0.4-0.0-0.20.2-0.4-0.4-0.3
Bone: cortical area0.81.21.91.11.11.10.71.1-0.91.11.41.2
Bone: cortical porosity0.00.00.10.20.30.30.00.1-0.10.30.20.2
Bone: cortical porosity0.00.10.10.20.20.20.00.3-0.10.20.40.2
Bone: cortical thickness0.00.00.0-0.1-0.1-0.1-0.2-0.00.2-0.10.20.1
Bone: cortical thickness0.00.00.10.10.10.00.30.0-0.10.0-0.0-0.1
Bone: cortical tissue density0.00.10.1-0.2-0.3-0.30.0-0.10.1-0.3-0.3-0.2
Bone: elastic displacement0.10.10.1-0.2-0.2-0.2-0.2-0.40.3-0.2-0.4-0.1
Bone: elastic work0.10.10.20.30.30.30.20.3-0.20.30.40.3
Bone: endosteal estimation3.57.58.12.82.82.82.72.6-2.72.92.62.7
Bone: endosteal perimeter2.55.05.82.32.42.41.82.1-2.12.42.32.3
Bone: final force4.77.68.22.92.82.82.72.7-2.72.82.72.8
Bone: final moment4.06.67.22.72.62.62.62.5-2.42.62.52.6
Bone: marrow area3.67.78.32.92.82.92.82.7-2.82.92.72.7
Bone: maximum diameter0.91.62.51.21.31.30.81.3-1.11.31.61.4
Bone: maximum force1.83.13.31.81.81.81.71.8-1.71.81.81.8
Bone: maximum moment1.42.42.61.61.51.61.51.5-1.51.61.61.5
Bone: minimum diameter2.54.66.42.12.22.31.52.1-1.92.32.52.2
Bone: periosteal estimation2.85.76.32.42.52.52.22.3-2.32.52.52.4
Bone: periosteal perimeter1.42.42.91.61.61.71.11.4-1.41.71.71.7
Bone: post-yield work0.20.30.40.60.60.60.30.5-0.50.60.50.4
Bone: stiffness1.32.02.21.51.41.41.51.5-1.41.41.41.4
Bone: tissue strength0.00.00.0-0.1-0.0-0.10.00.2-0.0-0.10.1-0.1
Bone: trabecular number1.52.32.8-1.5-1.7-1.7-1.4-1.21.3-1.7-1.5-1.7
Bone: trabecular spacing2.43.13.81.61.71.71.82.0-1.81.71.91.6
Bone: trabecular thickness0.10.10.40.20.10.10.60.1-0.30.1-0.20.2
Bone: trabecular tissue density0.10.10.3-0.2-0.3-0.30.1-0.20.1-0.3-0.6-0.2
Breakpoint value in progressive ratio session0.30.30.7-0.6-0.4-0.4-0.5-0.90.6-0.4-0.6-0.6
Distance traveled before self-admin1.11.11.71.01.01.01.01.1-1.01.01.01.3
Distance traveled after self-admin0.10.10.10.10.20.20.30.3-0.30.20.20.2
Delta time in closed arm before/after self-admin3.53.44.61.82.02.01.31.6-1.72.02.12.1
Delta time in open arm before/after self-admin1.11.01.1-0.9-1.1-1.1-0.9-1.01.0-1.1-1.1-1.0
Diff in mean of infusions in LGA sessions0.80.91.2-1.0-0.9-0.9-1.1-0.91.0-0.9-0.7-1.0
Extinction: sum of active levers before priming0.10.10.6-0.00.40.4-0.4-0.80.30.40.00.0
Active lever presses in extinction session 60.10.10.30.20.10.1-0.0-0.60.20.1-0.20.4
Delta distance traveled before/after self-admin0.70.71.4-0.9-0.8-0.8-0.8-0.80.8-0.8-0.7-1.2
Delta ambulatory time before/after self-admin1.11.22.2-1.2-1.1-1.1-0.8-1.00.9-1.1-1.0-1.5
Time in closed arm before self-admin0.20.20.6-0.4-0.1-0.1-0.80.20.2-0.10.5-0.7
Time in closed arm after self-admin0.50.61.20.70.90.90.10.6-0.60.91.10.6
Time in open arm before self-admin1.41.53.2-1.1-1.3-1.3-0.3-1.21.0-1.3-1.8-1.0
Time in open arm after self-admin3.84.26.1-2.0-2.3-2.3-1.3-1.91.9-2.3-2.5-1.9
Sum of active levers in priming session hrs 5-60.30.30.9-0.5-0.4-0.4-0.6-0.90.7-0.4-0.6-0.4
Time to tail flick, vehicle, before self-admin0.60.62.70.80.50.51.60.5-0.90.5-0.20.7
Time to tail flick, vehicle, after self-admin0.10.10.3-0.10.10.1-0.40.30.00.10.5-0.1
Time to tail flick, test, before self-admin0.30.30.5-0.5-0.6-0.6-0.3-0.40.4-0.6-0.7-0.4
Time to tail flick, test, after self-admin1.01.02.3-0.8-0.9-0.90.1-1.00.7-0.9-1.5-1.5
Delta time to tail flick, vehicle, before/after SA0.40.41.7-0.6-0.3-0.3-1.3-0.20.7-0.30.3-0.5
Delta time to tail flick, test, before/after SA0.70.61.60.80.80.81.30.7-0.90.80.50.4
Ambulatory time before self-admin0.40.40.80.60.60.60.60.5-0.60.60.40.9
Ambulatory time after self-admin0.40.40.6-0.7-0.7-0.7-0.2-0.50.5-0.7-0.7-0.8
Total heroin consumption1.41.62.9-1.3-1.4-1.4-0.6-1.21.1-1.4-1.7-1.1
Area under the delay curve1.21.31.71.10.91.11.21.3-1.10.91.11.3
Delay disc. indifference point, 0s delay1.21.33.01.01.11.20.41.2-0.91.11.71.2
Delay disc. indifference point, 16s delay0.10.10.30.1-0.20.10.5-0.40.0-0.2-0.60.3
Delay disc. indifference point, 2s delay0.10.10.50.00.00.3-0.10.7-0.10.00.70.2
Delay disc. indifference point, 24s delay2.42.32.81.61.41.61.61.5-1.61.41.31.7
Delay disc. indifference point, 4s delay1.92.02.41.41.41.41.31.5-1.41.41.51.5
Delay disc. indifference point, 8s delay1.81.83.01.31.11.31.71.5-1.41.11.11.5
Delay discount exponential model param0.91.01.4-1.0-0.8-1.0-1.1-1.21.0-0.8-1.0-1.1
Delay discount hyperbolic model param0.70.71.1-0.8-0.6-0.9-0.9-1.10.8-0.6-0.9-1.0
Fecal boli incidents, locomotor time 10.00.00.1-0.0-0.2-0.2-0.00.10.0-0.3-0.0-0.1
Change in fecal boli incidents, locomotor task3.43.27.31.42.01.80.41.9-1.42.02.71.6
Time >=10cm from walls, locomotor time 13.43.44.81.72.01.91.31.9-1.72.02.21.8
Bouts of movement, locomotor time 10.50.61.0-0.6-0.8-0.7-0.5-0.90.8-0.9-1.0-0.5
Total resting periods, locomotor time 10.30.40.9-0.4-0.6-0.6-0.2-0.80.5-0.7-0.9-0.5
Rest time, locomotor task time 10.20.20.40.40.40.60.30.5-0.40.40.60.4
Distance moved, locomotor task time 10.10.10.30.30.30.20.4-0.2-0.20.4-0.10.5
Vertical activity count, locomotor time 10.50.50.70.70.60.70.90.5-0.70.70.50.8
Time >=10cm from walls, locomotor time 212.513.318.93.43.93.62.53.9-3.53.84.43.5
Bouts of movement, locomotor time 20.10.10.30.0-0.1-0.10.4-0.50.1-0.0-0.60.0
Total resting periods, locomotor time 20.20.20.5-0.3-0.3-0.4-0.1-0.70.4-0.3-0.6-0.3
Rest time, locomotor task time 20.00.10.20.20.20.3-0.10.3-0.10.20.40.1
Distance moved, locomotor task time 22.12.43.21.51.71.71.61.2-1.61.81.21.7
Vertical activity count, locomotor time 21.31.51.91.11.31.31.21.2-1.21.41.21.1
Weight adjusted by age4.14.68.41.82.32.20.92.4-2.02.22.92.0
Seeking ratio, delayed vs. immediate footshock0.80.92.5-0.6-1.1-0.90.1-0.80.6-1.1-1.6-0.7
Locomotion in novel chamber0.20.20.5-0.5-0.4-0.5-0.70.50.3-0.30.5-0.4
Locomotion in novel chamber post-restriction1.92.22.51.41.51.61.51.6-1.51.51.41.2
Progressive ratio1.31.54.01.31.01.32.00.9-1.41.00.41.1
Food seeking constrained by brief footshock0.00.10.2-0.2-0.1-0.2-0.3-0.10.2-0.20.0-0.4
Seeking ratio, punishment vs. effort0.60.72.9-0.8-0.5-0.7-1.7-0.40.9-0.50.2-0.7
Run reversals in cocaine runway, females0.10.10.30.2-0.00.00.6-0.40.0-0.3-0.60.1
Run reversals in cocaine runway, males1.41.33.8-0.9-1.0-1.10.6-1.20.6-1.1-2.0-1.3
Latency to leave start box in cocaine runway0.40.51.10.30.90.9-1.0-0.10.10.71.10.3
Latency to leave start box in cocaine runway, F0.40.41.10.30.80.8-1.1-0.20.10.60.90.2
Latency to leave start box in cocaine runway, M0.20.20.50.20.60.5-0.10.3-0.20.50.70.5
Cd content in liver0.50.51.10.80.60.71.00.8-0.90.60.40.7
Co content in liver2.63.03.71.71.81.81.61.6-1.81.91.71.8
Cu content in liver2.83.44.3-2.0-1.9-2.0-2.1-1.41.8-2.0-1.4-2.0
Fe content in liver3.23.84.62.01.91.92.11.8-2.12.11.61.9
K content in liver0.80.81.8-0.9-0.9-0.8-1.4-0.80.9-1.0-0.6-0.8
Mg content in liver1.41.53.4-1.3-1.1-1.1-1.8-1.01.3-1.2-0.7-1.1
Mn content in liver0.00.00.1-0.00.0-0.0-0.40.10.0-0.10.2-0.0
Na content in liver0.20.20.4-0.5-0.4-0.4-0.5-0.50.3-0.5-0.6-0.4
Rb content in liver0.30.30.40.50.60.60.50.5-0.50.50.60.6
Se content in liver2.22.64.4-1.7-1.6-1.6-2.1-1.41.6-1.7-1.1-1.6
Sr content in liver0.00.00.0-0.1-0.0-0.0-0.10.00.0-0.00.1-0.0
Zn content in liver3.53.87.71.82.02.01.12.2-1.61.82.82.0