Hub : Genes

Bbip1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000047019 0.04 0.02 2.8e-05 0.04 0.04 0.04 0.04 3.4e-05 5.8e-05 5.9e-05 3.6e-05
2 BLA gene expression ENSRNOG00000047019 0.31 0.12 2.6e-13 0.19 0.25 0.25 0.23 3.2e-10 9.8e-14 1.4e-13 1.9e-12
3 Brain gene expression ENSRNOG00000047019 0.19 0.08 0.0e+00 0.22 0.2 0.2 0.2 5.2e-20 1.1e-18 6.9e-18 1.3e-18
4 Brain mRNA stability ENSRNOG00000047019 0.04 0.02 4.1e-03 0.03 0.02 0.03 0.03 9.9e-04 4.0e-03 1.7e-03 1.9e-03
5 IL gene expression ENSRNOG00000047019 0.15 0.1 5.5e-03 0.01 0.11 0.07 0.05 1.9e-01 1.6e-03 1.1e-02 2.4e-02
6 LHb gene expression ENSRNOG00000047019 0.18 0.1 3.1e-03 0.03 0.06 0.05 0.03 8.4e-02 1.3e-02 2.7e-02 6.5e-02
7 Liver gene expression ENSRNOG00000047019 0.1 0.05 1.7e-11 0.08 0.07 0.07 0.07 4.3e-09 3.5e-08 2.4e-08 2.7e-08
8 NAcc gene expression ENSRNOG00000047019 0.32 0.16 3.6e-11 0.16 0.15 0.15 0.15 5.8e-12 3.1e-11 1.4e-11 1.5e-11
9 OFC gene expression ENSRNOG00000047019 0.37 0.15 4.7e-06 0.24 0.22 0.19 0.22 2.2e-06 6.3e-06 2.7e-05 4.6e-06
10 PL gene expression ENSRNOG00000047019 0.29 0.1 0.0e+00 0.24 0.27 0.28 0.27 1.8e-18 7.2e-21 4.8e-21 8.6e-21
11 PL intron excision ratio chr1:252958487:252959032 0.09 0.05 2.9e-03 0.05 0.03 0.02 0.03 2.0e-04 2.3e-03 9.1e-03 1.3e-03
12 PL mRNA stability ENSRNOG00000047019 0.05 0.03 1.8e-03 0.03 0.03 0.03 0.03 1.4e-03 2.2e-03 4.6e-03 3.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail1.85.819.92.51.62.32.01.22.92.02.02.02.44.52.0
BMI without tail1.53.14.61.91.91.71.80.42.11.31.81.82.11.91.8
Body weight2.510.537.33.11.93.02.81.54.02.62.72.93.26.12.7
Epididymis fat weight1.32.927.21.0-0.30.80.5-0.71.90.60.40.61.05.20.5
Glucose1.11.66.91.10.51.11.11.01.51.01.11.11.12.61.1
Heart weight3.55.07.9-2.3-2.8-2.3-2.4-1.1-2.2-2.2-2.5-2.4-2.60.4-2.5
Left kidney weight3.510.013.13.32.73.33.23.63.43.03.23.33.12.63.2
Right kidney weight2.16.08.12.51.82.42.52.52.72.32.52.42.52.82.4
Tail length0.00.10.6-0.10.10.10.1-0.80.2-0.10.00.10.20.50.1
Length with tail0.62.49.41.20.71.41.30.71.91.31.31.41.43.11.3
Length without tail0.92.014.40.8-0.21.00.81.21.61.00.80.90.73.80.7
Liver weight, left0.81.37.5-0.5-1.4-0.8-0.9-1.0-0.2-0.8-1.0-0.8-0.82.7-0.9
Liver weight, right3.25.418.62.31.42.12.10.92.81.82.12.12.24.32.1
Parametrial fat weight0.91.714.50.7-0.00.90.6-0.51.40.70.60.60.83.80.5
Retroperitoneal fat weight3.411.432.53.22.33.03.11.14.12.93.13.23.65.73.0
Intraocular pressure0.30.51.7-0.4-0.6-0.3-0.6-1.3-0.0-0.2-0.6-0.6-0.31.3-0.6
Extensor digitorum longus weight0.41.73.0-1.2-1.6-1.2-1.2-1.7-0.6-1.3-1.2-1.1-1.11.7-1.2
Soleus weight2.05.716.02.31.52.32.21.82.82.32.22.12.24.02.2
Tibialis anterior weight0.41.52.8-1.3-1.3-1.2-1.4-1.7-1.0-1.0-1.3-1.3-1.20.1-1.4
Tibia length0.82.37.41.30.91.41.42.71.51.31.41.41.21.71.4
Number of licking bursts0.40.41.0-0.7-0.9-0.6-0.5-0.9-0.1-0.7-0.5-0.5-0.51.0-0.5
Food consumed during 24 hour testing period0.50.60.90.70.91.00.80.40.71.00.80.80.80.10.8
Times rat made contact with spout0.40.54.7-0.1-0.8-0.1-0.20.00.30.1-0.2-0.2-0.22.2-0.2
Mean time between licks in bursts0.10.21.4-0.20.1-0.2-0.3-1.2-0.2-0.0-0.3-0.30.1-0.3-0.3
Mean num. licks in bursts0.50.61.41.00.60.90.71.20.61.10.70.70.60.50.7
Std. dev. time between licks in bursts0.60.72.8-0.7-0.6-0.8-0.9-1.7-0.6-0.6-0.9-0.9-0.5-0.1-0.9
Water consumed over 24 hours1.82.12.91.51.21.61.41.31.51.71.41.41.51.31.4
Indifference point 0 sec0.30.64.20.1-0.40.30.40.80.60.60.50.40.42.10.4
Indifference point AUC1.51.83.3-1.4-1.7-1.3-1.3-1.3-0.7-1.1-1.1-1.3-1.31.8-1.3
Indifference point function ln k0.40.51.00.60.80.80.60.70.40.90.60.60.7-1.00.6
Indifference point function log k0.40.51.00.60.80.80.60.70.40.90.60.60.7-1.00.6
Delay discounting total patch changes 0 sec0.30.55.0-0.1-0.70.00.10.40.40.20.10.10.12.20.0
Delay discounting total patch changes 12 sec0.71.03.1-1.1-1.3-1.0-0.8-0.9-0.4-0.8-0.6-0.7-0.81.8-0.8
Delay discounting total patch changes 18 sec1.72.37.8-1.4-2.1-1.2-1.3-1.3-0.5-1.3-1.1-1.2-1.22.8-1.3
Delay discounting total patch changes 24 sec0.91.14.0-1.0-1.4-1.0-0.8-1.3-0.2-0.8-0.7-0.8-0.62.0-0.8
Delay discounting total patch changes 6 sec0.50.77.4-0.1-0.7-0.10.00.30.50.00.20.1-0.02.7-0.0
Delay discounting time to switch 0 sec0.81.33.01.11.71.11.00.70.60.91.11.01.1-1.71.1
Delay discounting water rate 0 sec0.30.52.4-0.5-1.2-0.5-0.6-0.2-0.1-0.4-0.7-0.7-0.61.6-0.6
Delay discounting water rate 12 sec0.30.52.10.60.30.80.50.10.90.60.40.50.71.40.5
Delay discounting water rate 18 sec0.40.50.60.70.60.70.80.70.70.70.70.70.80.50.7
Delay discounting water rate 24 sec0.40.52.60.50.40.60.60.50.90.50.50.50.71.60.6
Delay discounting water rate 6 sec0.40.72.00.90.30.80.70.80.90.70.50.60.81.40.7
Locomotor activity0.10.10.80.0-0.30.10.10.9-0.00.30.0-0.0-0.10.80.0
Locomotor testing distance0.30.52.80.60.20.60.71.70.40.80.50.50.40.70.6
Locomotor testing rearing0.71.12.41.11.11.21.21.50.91.01.11.01.00.31.1
Light reinforcement 10.81.52.4-1.3-1.1-1.5-1.2-0.7-1.4-1.6-1.0-1.2-1.3-1.4-1.2
Light reinforcement 20.81.01.7-1.3-0.9-1.1-1.0-0.8-1.3-0.6-0.9-0.9-1.0-1.3-1.0
Reaction time number correct2.33.34.31.91.81.91.81.12.12.01.81.72.01.71.9
Reaction time mean minus median0.40.50.70.80.60.50.80.50.80.30.70.70.70.70.8
Reaction time mean minus median AUC1.31.62.41.61.31.31.41.01.41.01.31.21.40.81.3
Reaction time num false alarms1.31.92.4-1.4-1.5-1.4-1.5-1.5-1.3-0.8-1.5-1.5-1.5-0.1-1.5
Reaction time num false alarms AUC1.62.23.1-1.6-1.7-1.6-1.7-1.2-1.5-1.0-1.7-1.6-1.7-0.0-1.6
Reaction time trials correct on left2.33.34.31.91.81.91.81.12.12.01.81.72.01.71.9
Reaction time trials on left2.43.44.41.91.91.91.91.12.12.01.81.72.11.71.9
Reaction time mean0.71.01.31.11.10.91.11.10.90.71.01.10.9-0.21.2
Reaction time mean AUC0.40.61.00.91.00.70.80.80.60.50.70.70.7-0.60.9
Median of all reaction times0.91.31.91.21.31.11.21.40.91.01.21.21.0-0.41.3
Reaction time omissions1.11.43.21.31.81.01.30.41.01.21.21.31.5-0.21.3
Reaction time false alarm rate3.85.46.6-2.5-2.5-2.5-2.5-2.0-2.5-2.0-2.5-2.3-2.6-1.1-2.5
Reaction time premature initiation rate0.30.32.5-0.1-0.5-0.1-0.11.1-0.00.2-0.1-0.1-0.31.6-0.1
Reaction time premature initiations1.21.76.91.00.51.01.01.81.21.30.90.90.92.61.0
Std. dev. reaction times0.60.81.31.10.90.81.00.51.10.50.80.81.00.91.0
Reaction time trials completed2.43.44.41.91.91.91.91.12.12.01.81.72.11.71.9
Reaction time trials AUC2.33.34.31.91.81.91.81.12.11.91.81.72.01.71.8
Social response proportion10.211.113.63.53.23.43.62.83.63.43.53.43.71.93.6
Social responses2.83.65.42.01.51.72.01.32.31.61.81.82.12.32.0
Social time5.67.411.12.62.52.62.92.42.83.32.92.83.11.32.9
Conditioned locomotion0.80.91.4-0.9-1.2-1.0-1.1-0.2-0.9-1.0-1.1-1.1-1.10.4-1.1
Cocaine response after cond. corrected0.40.54.2-0.40.3-0.3-0.10.3-0.7-0.60.0-0.1-0.4-2.1-0.1
Cocaine response after cond. not corrected0.70.84.7-0.8-0.1-0.6-0.40.3-1.1-0.9-0.3-0.4-0.8-2.2-0.4
Cocaine response before conditioning0.20.30.5-0.6-0.7-0.4-0.6-0.2-0.5-0.4-0.7-0.6-0.50.0-0.6
Saline control response0.20.20.4-0.4-0.5-0.4-0.40.2-0.5-0.3-0.5-0.4-0.5-0.7-0.4
Condit. Reinf. active minus inactive responses7.79.514.9-3.1-3.2-3.2-3.2-3.9-2.8-3.0-3.3-3.2-3.0-1.2-3.2
Condit. Reinf. active-inactive response ratio7.07.49.2-2.7-2.6-2.8-2.8-3.0-2.7-2.7-2.9-2.8-2.7-1.8-2.8
Condit. Reinf. active responses5.47.412.3-2.7-2.9-2.9-2.8-3.5-2.4-2.7-2.9-2.8-2.7-0.4-2.8
Condit. Reinf. inactive responses0.60.81.8-0.8-1.0-0.9-0.9-1.3-0.6-0.8-0.9-0.9-0.80.7-0.9
Condit. Reinf. lever presses5.57.69.2-2.8-3.0-2.9-2.9-2.8-2.5-2.9-2.9-2.9-2.9-0.4-2.9
Condit. Reinf. lever reinforcers received5.57.812.1-2.8-3.0-2.9-2.9-3.5-2.5-2.7-3.0-2.9-2.8-0.6-2.9
Pavlov. Cond. lever latency4.56.17.82.62.82.62.62.72.12.62.62.62.5-0.02.6
Pavlov. Cond. magazine entry latency0.30.32.5-0.1-0.4-0.1-0.1-0.80.4-0.1-0.1-0.10.11.6-0.1
Pavlov. Cond. change in total contacts2.23.16.2-1.8-2.1-1.8-1.8-2.5-1.2-1.7-1.8-1.8-1.60.5-1.8
Pavlov. Cond. index score1.52.03.8-1.4-1.7-1.4-1.4-1.9-0.8-1.4-1.4-1.4-1.31.1-1.4
Pavlov. Cond. latency score1.11.43.2-1.1-1.4-1.1-1.2-1.8-0.6-1.1-1.1-1.2-1.01.2-1.2
Pavlov. Cond. lever contacts4.25.98.1-2.6-2.9-2.5-2.6-2.3-2.1-2.5-2.5-2.6-2.60.2-2.6
Pavlov. Cond. magazine entry number0.20.32.30.10.40.10.10.9-0.40.00.10.1-0.1-1.50.1
Pavlov. Cond. intertrial magazine entries0.40.50.9-0.8-0.6-0.8-0.7-0.2-0.9-0.9-0.7-0.7-0.8-0.4-0.7
Pavlov. Cond. lever-magazine prob. diff.1.41.83.5-1.3-1.7-1.3-1.3-1.9-0.8-1.3-1.3-1.3-1.21.1-1.3
Pavlov. Cond. response bias3.34.66.6-2.2-2.6-2.2-2.2-2.3-1.7-2.2-2.2-2.2-2.20.6-2.2
Conditioned reinforcement - actives0.80.81.31.11.11.10.90.30.90.90.80.91.0-0.50.9
Conditioned reinforcement - inactives0.20.21.3-0.1-0.4-0.1-0.2-0.80.20.2-0.2-0.3-0.11.2-0.2
Conditioned locomotion3.44.15.52.32.22.32.11.72.31.52.02.22.20.82.1
Intermittent access intake day 1-15 change1.11.12.81.10.91.10.9-0.31.31.00.90.81.31.70.9
Intermittent access intake escalation1.51.52.51.41.11.41.10.21.51.41.01.01.51.61.1
Intermittent access intake escalation 22.42.43.61.71.41.71.40.51.91.61.61.51.81.31.4
Intermitt. access day 1 inactive lever presses0.80.92.6-1.2-1.3-0.9-0.7-1.2-0.1-0.6-0.6-0.7-0.81.6-0.7
Intermitt. access day 15 inactive lever presses0.30.30.9-0.6-0.3-0.7-0.4-0.7-0.50.1-0.5-0.4-0.4-0.9-0.4
Intermitt. access escalation Index0.60.51.00.70.70.60.90.80.9-0.41.00.70.70.50.9
Intermittent access day 1 total infusions0.30.41.6-0.6-0.5-0.5-0.6-1.3-0.3-0.5-0.7-0.6-0.30.5-0.6
Intermittent access day 15 total infusions0.40.41.90.30.30.40.2-1.10.80.30.10.20.71.40.2
Intermittent access terminal intake (last 3 days)0.50.51.10.60.50.60.4-0.91.00.60.40.41.01.00.4
Intermittent access total infusions0.30.31.60.30.20.30.2-1.00.70.30.10.20.61.30.2
Intermittent access day 1 locomotion0.00.00.10.10.20.20.10.10.2-0.30.20.20.1-0.20.1
Intermittent access day 15 total locomotion0.30.32.20.50.20.70.2-0.30.80.20.20.10.41.50.2
Intermittent access total locomotion0.91.01.41.01.01.11.00.81.20.81.11.01.10.71.0
Intermittent access standard deviation1.81.93.81.71.21.41.0-0.41.81.60.91.11.71.91.0
Cocaine induced anxiety0.60.73.70.40.40.30.51.9-0.20.70.40.50.2-1.60.5
Post-drug Anxiety0.10.21.20.10.1-0.00.21.1-0.00.30.30.40.2-0.50.2
Baseline Anxiety1.92.06.9-1.2-1.6-1.2-1.1-2.1-0.3-1.6-1.0-1.0-0.92.6-1.1
Lifetime Intake0.40.42.00.50.30.50.2-1.00.80.70.10.20.71.40.2
Incentive Sensitization - Responses1.01.02.01.11.21.10.9-0.31.21.10.80.91.40.70.9
Incentive Sensitization - Breakpoint0.90.91.71.01.11.00.9-0.41.21.00.70.81.30.80.9
Progressive ratio test 1 active lever presses0.30.40.60.60.80.60.6-0.20.80.50.50.60.80.40.6
Progressive ratio test 1 breakpoint0.10.10.30.10.40.10.3-0.50.40.20.30.30.5-0.00.3
Progressive ratio test 1 inactive lever presses0.50.62.1-0.8-0.6-0.8-0.6-1.4-0.3-0.9-0.6-0.6-0.60.5-0.6
Progressive ratio test 2 active lever presses1.71.82.91.51.61.51.3-0.11.61.41.11.31.70.91.3
Progressive ratio test 2 breakpoint1.31.42.31.31.41.31.1-0.31.51.11.01.11.51.01.1
Progressive ratio test 2 inactive lever presses0.40.51.00.50.80.50.6-0.71.00.50.50.61.00.70.6
Total sessions with >9 infusions2.02.25.01.50.91.71.10.61.81.91.11.11.72.21.1
Short access day 1 total inactive lever presses0.40.52.10.60.30.70.5-0.31.00.30.60.50.61.40.5
Short access day 10 total inactive lever presses0.10.11.0-0.2-0.2-0.20.1-0.30.3-0.10.20.1-0.11.00.1
Short access day 1 total infusions2.22.34.71.81.41.71.30.61.82.21.11.41.81.41.3
Short access day 10 total infusions0.10.11.1-0.2-0.2-0.2-0.3-1.00.00.0-0.4-0.3-0.10.3-0.3
Short access total infusions0.50.51.40.70.60.60.4-0.50.81.10.20.40.91.20.4
Short access day 1 locomotion2.22.34.51.61.31.81.30.51.82.11.31.41.81.41.3
Short access day 10 total locomotion1.51.72.31.21.11.31.31.51.51.31.41.31.50.71.3
Short access total locomotion1.01.01.30.90.91.11.00.91.11.11.11.01.10.61.0
Compulsive drug intake0.20.20.5-0.4-0.3-0.3-0.3-0.3-0.2-0.7-0.2-0.2-0.60.4-0.3
One hour access (0.3 mA shock)2.12.55.51.51.31.61.4-0.62.11.61.21.31.92.31.4
One hour access (shock baseline)1.11.32.41.10.91.30.9-0.31.41.50.90.81.61.20.9
Number of responses in last shaping day0.30.30.70.80.50.80.50.60.60.70.50.60.50.50.5
Context. condit. distance diff. score0.60.71.3-1.0-0.5-0.9-0.8-0.2-1.1-1.0-0.8-0.7-1.0-1.0-0.8
Locomotion velocity, session 12.83.13.7-1.6-1.7-1.8-1.9-1.8-1.8-1.8-1.9-1.9-1.9-0.7-1.9
Locomotion distance, session 10.20.20.3-0.5-0.5-0.5-0.50.1-0.5-0.5-0.5-0.4-0.6-0.4-0.5
Locomotion velocity, session 20.20.21.40.50.40.40.21.20.00.50.20.20.1-0.60.2
Locomotion distance, session 20.30.52.0-0.5-1.0-0.6-0.6-0.2-0.2-0.5-0.6-0.6-0.61.4-0.6
Locomotion velocity, session 31.31.52.4-1.5-1.4-1.4-1.2-0.6-1.3-1.5-1.2-1.2-1.4-0.2-1.2
Locomotion distance, session 32.52.74.1-1.9-1.7-1.8-1.7-0.8-1.8-1.9-1.7-1.6-2.0-0.5-1.7
Stereotopy head waving bouts, day 30.00.00.10.20.10.20.20.10.20.30.20.20.30.30.2
Stereotopy head waving duration, day 30.10.10.5-0.2-0.2-0.3-0.2-0.4-0.2-0.2-0.2-0.2-0.0-0.7-0.2
Locomotion velocity, session 71.51.72.4-1.3-1.5-1.3-1.5-1.2-1.2-1.1-1.5-1.3-1.40.1-1.5
Locomotion distance, session 71.01.31.8-1.2-1.2-1.2-1.2-0.3-1.2-1.2-1.2-1.1-1.40.1-1.2
Stereotopy head waving bouts, day 70.70.81.2-0.9-1.1-1.0-1.0-0.9-0.8-1.0-1.0-0.9-0.90.1-1.0
Stereotopy head waving duration, day 70.70.81.3-0.8-1.1-1.0-0.9-1.1-0.7-0.9-0.9-0.9-0.80.5-0.9
Locomotion velocity, session 80.10.10.3-0.2-0.3-0.3-0.30.2-0.4-0.2-0.3-0.3-0.3-0.6-0.3
Locomotion distance, session 80.40.60.9-1.0-0.8-0.9-0.80.0-0.9-0.9-0.8-0.7-1.0-0.4-0.8
Degree of sensitization distance0.20.20.40.50.50.50.30.00.40.50.30.40.60.10.3
Degree of sensitization stereotypy1.71.92.6-1.4-1.6-1.5-1.5-1.1-1.3-1.5-1.5-1.4-1.40.2-1.5
Condit. Reinf. active minus inactive responses2.42.73.1-1.6-1.6-1.7-1.8-1.7-1.7-1.6-1.8-1.7-1.6-1.3-1.8
Condit. Reinf. active-inactive response ratio1.01.12.2-1.0-0.7-1.1-1.0-1.2-1.1-1.1-1.0-0.9-0.9-1.5-1.0
Condit. Reinf. active responses3.44.15.1-2.0-2.3-2.1-2.2-2.2-1.8-2.0-2.2-2.2-2.0-0.6-2.2
Condit. Reinf. inactive responses1.11.32.2-1.1-1.5-1.2-1.2-1.4-0.7-1.1-1.2-1.2-1.00.5-1.2
Incentive salience index mean3.03.74.1-1.9-1.7-2.0-2.0-1.9-2.0-1.9-2.0-1.9-1.8-2.0-2.0
Condit. Reinf. lever presses1.21.62.5-1.3-1.0-1.4-1.2-1.5-1.2-1.3-1.2-1.2-1.1-1.6-1.2
Time in familiar zone, hab. session 11.91.82.71.31.61.11.41.40.91.21.41.41.4-1.51.4
Time in novel zone, hab. session 11.71.72.5-1.3-1.6-1.1-1.2-1.5-0.7-1.3-1.2-1.3-1.21.5-1.2
Total zone transitions, hab. session 10.91.32.7-0.9-1.6-0.9-1.2-0.4-0.7-0.8-1.2-1.3-1.11.5-1.2
Total locomotion distance, hab. session 10.60.81.7-0.9-1.3-0.8-1.0-0.7-0.6-0.7-1.0-0.9-0.90.9-1.0
Locomotion velocity, hab. session 10.81.12.0-1.0-1.4-1.0-1.2-0.8-0.8-0.9-1.2-1.2-1.10.7-1.2
Time in familiar zone, hab. session 20.20.21.6-0.2-0.2-0.3-0.1-1.30.2-0.3-0.1-0.10.10.8-0.1
Time in novel zone, hab. session 20.10.11.10.10.20.20.31.1-0.10.10.30.3-0.0-0.50.3
Total zone transitions, hab. session 20.30.40.9-0.6-0.9-0.6-0.6-0.4-0.3-0.4-0.6-0.6-0.50.9-0.6
Total locomotion distance, hab. session 20.50.61.3-0.9-1.1-0.8-0.7-0.6-0.4-0.7-0.7-0.7-0.71.0-0.7
Locomotion velocity, hab. session 20.50.71.4-0.9-1.2-0.8-0.8-0.6-0.5-0.7-0.8-0.8-0.80.9-0.8
Novel to familiar place preference ratio0.10.10.20.30.30.30.3-0.20.40.30.30.20.40.40.3
Novelty place preference0.30.30.60.60.60.60.6-0.10.70.50.60.60.80.60.6
Time in novel zone, NPP test0.30.30.70.50.50.60.5-0.40.80.50.50.50.80.80.5
Total zone transitions, NPP test1.01.52.6-1.0-1.6-1.1-1.3-0.9-0.7-1.0-1.3-1.4-1.21.5-1.3
Total locomotion distance, NPP test0.91.32.3-1.0-1.5-1.1-1.2-1.0-0.7-0.9-1.2-1.2-1.11.3-1.2
Locomotion velocity, NPP test0.60.81.5-0.8-1.2-0.9-1.0-0.5-0.6-0.7-1.0-1.0-0.91.0-1.0
Pavlov. Cond. lever latency0.10.11.40.10.00.10.10.20.3-0.00.10.10.11.20.1
Pavlov. Cond. magazine entry latency0.00.00.2-0.2-0.2-0.1-0.0-0.40.1-0.1-0.00.10.10.4-0.0
Pavlov. Cond. change in total contacts0.00.00.0-0.00.00.10.10.10.10.10.10.20.1-0.20.1
Pavlov. Cond. index score0.00.00.1-0.1-0.2-0.1-0.0-0.20.0-0.1-0.00.1-0.00.0-0.0
Pavlov. Cond. latency score0.00.00.10.0-0.00.10.2-0.10.20.10.20.20.2-0.10.2
Pavlov. Cond. lever contacts0.10.21.5-0.3-0.1-0.2-0.1-0.6-0.2-0.2-0.1-0.0-0.1-1.2-0.1
Pavlov. Cond. magazine entry number0.10.20.8-0.2-0.0-0.3-0.30.0-0.6-0.3-0.3-0.4-0.4-0.9-0.3
Pavlov. Cond. intertrial magazine entries0.40.50.9-0.7-0.9-0.9-0.7-0.3-0.7-0.9-0.7-0.7-0.8-0.2-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.3-0.4-0.3-0.2-0.5-0.1-0.3-0.2-0.1-0.20.0-0.2
Pavlov. Cond. response bias0.00.00.10.10.00.10.2-0.20.20.10.20.20.2-0.20.2
Bone: apparent density0.50.83.70.80.60.90.7-0.31.20.10.70.70.71.90.7
Bone surface0.20.41.40.70.60.70.60.30.70.10.60.50.51.20.6
Bone volume0.71.26.30.90.61.00.90.11.30.30.90.80.92.50.9
Bone: connectivity density0.30.51.10.91.10.90.70.30.70.70.70.70.70.00.7
Bone: cortical apparent density0.40.52.1-0.5-0.4-0.4-0.40.8-0.8-0.5-0.4-0.4-0.8-1.4-0.4
Bone: cortical area1.11.68.7-1.0-1.7-0.8-0.9-0.7-0.2-1.2-0.9-1.0-0.92.9-0.9
Bone: cortical porosity0.10.10.4-0.0-0.10.00.0-0.60.2-0.20.00.00.10.60.0
Bone: cortical porosity0.10.20.7-0.2-0.4-0.2-0.1-0.80.2-0.5-0.1-0.1-0.00.8-0.1
Bone: cortical thickness1.11.84.7-1.3-1.9-1.1-1.2-0.1-0.7-1.4-1.2-1.2-1.42.2-1.2
Bone: cortical thickness0.60.72.1-0.8-1.3-0.7-0.70.3-0.4-0.6-0.7-0.7-0.81.4-0.7
Bone: cortical tissue density0.40.52.4-0.4-0.4-0.4-0.40.8-0.8-0.4-0.4-0.4-0.8-1.6-0.4
Bone: elastic displacement0.00.00.1-0.00.00.00.0-0.30.10.30.00.10.2-0.30.0
Bone: elastic work0.40.61.30.50.40.60.70.60.81.10.70.70.90.80.7
Bone: endosteal estimation0.92.03.71.31.21.31.50.31.70.91.51.41.71.91.5
Bone: endosteal perimeter0.40.86.30.60.10.50.60.11.10.30.60.50.72.50.6
Bone: final force0.60.94.00.60.40.80.90.81.20.40.90.90.82.00.9
Bone: final moment0.71.24.90.80.51.01.00.81.30.61.01.01.02.21.0
Bone: marrow area0.92.03.81.31.21.31.50.31.80.91.51.41.72.01.5
Bone: maximum diameter1.01.811.8-0.9-1.8-0.9-0.8-0.90.0-1.2-0.8-0.9-0.73.4-0.8
Bone: maximum force0.20.42.60.20.00.50.40.30.7-0.00.40.30.41.60.4
Bone: maximum moment0.30.53.40.40.10.60.50.20.90.10.50.40.61.80.5
Bone: minimum diameter0.20.43.5-0.4-0.6-0.3-0.0-0.60.3-0.6-0.0-0.10.01.9-0.0
Bone: periosteal estimation0.61.210.00.5-0.00.60.70.11.30.20.70.60.83.20.7
Bone: periosteal perimeter0.91.515.40.2-0.60.30.30.11.0-0.10.30.20.33.90.3
Bone: post-yield work0.70.92.4-1.0-0.7-0.8-0.9-1.5-0.8-1.4-0.9-0.9-0.9-0.2-0.9
Bone: stiffness0.00.00.2-0.0-0.00.30.10.20.2-0.30.10.0-0.10.40.1
Bone: tissue strength0.20.21.2-0.10.3-0.2-0.1-0.7-0.30.0-0.1-0.10.1-1.1-0.1
Bone: trabecular number0.50.81.21.01.11.00.9-0.31.10.40.90.90.90.60.9
Bone: trabecular spacing1.62.12.6-1.6-1.6-1.6-1.5-1.0-1.5-1.5-1.5-1.5-1.5-0.6-1.5
Bone: trabecular thickness1.51.910.01.00.61.11.10.01.70.91.11.11.23.21.1
Bone: trabecular tissue density0.10.10.3-0.4-0.5-0.3-0.30.2-0.3-0.5-0.3-0.3-0.50.1-0.3
Breakpoint value in progressive ratio session0.10.10.30.00.20.00.2-0.60.3-0.10.20.20.5-0.10.3
Distance traveled before self-admin0.20.21.0-0.1-0.0-0.4-0.20.8-0.6-0.1-0.20.0-0.4-1.0-0.2
Distance traveled after self-admin2.52.85.41.61.61.41.92.31.41.41.82.01.60.21.9
Delta time in closed arm before/after self-admin0.20.20.60.10.40.20.30.8-0.20.20.20.50.1-0.80.4
Delta time in open arm before/after self-admin0.20.21.30.2-0.20.1-0.0-0.70.50.00.1-0.10.21.2-0.1
Diff in mean of infusions in LGA sessions2.22.57.0-1.7-1.0-1.8-1.3-1.1-1.8-1.9-1.0-1.1-1.3-2.7-1.3
Extinction: sum of active levers before priming0.00.00.2-0.3-0.1-0.0-0.0-0.30.0-0.30.10.00.00.40.1
Active lever presses in extinction session 60.90.81.4-0.9-1.2-0.9-1.0-0.7-0.8-0.7-1.0-1.0-0.90.7-1.0
Delta distance traveled before/after self-admin4.24.45.52.12.02.02.41.82.21.92.42.32.21.42.3
Delta ambulatory time before/after self-admin2.42.73.51.61.51.51.81.01.91.41.81.71.71.51.8
Time in closed arm before self-admin0.00.00.20.0-0.0-0.0-0.0-0.10.00.40.10.00.1-0.2-0.0
Time in closed arm after self-admin0.40.43.8-0.40.2-0.2-0.2-0.3-0.70.2-0.2-0.1-0.0-1.9-0.1
Time in open arm before self-admin0.20.20.4-0.6-0.4-0.5-0.5-0.1-0.6-0.6-0.5-0.4-0.6-0.5-0.5
Time in open arm after self-admin0.20.21.1-0.1-0.5-0.2-0.2-0.70.2-0.5-0.2-0.4-0.21.1-0.3
Sum of active levers in priming session hrs 5-60.40.40.7-0.6-0.7-0.8-0.7-0.6-0.7-0.8-0.7-0.7-0.6-0.2-0.6
Time to tail flick, vehicle, before self-admin0.90.95.10.70.20.70.70.41.10.80.60.70.92.30.8
Time to tail flick, vehicle, after self-admin0.20.20.60.70.30.40.30.70.40.10.40.30.20.80.2
Time to tail flick, test, before self-admin0.30.30.80.40.20.50.30.90.40.80.30.40.40.60.4
Time to tail flick, test, after self-admin0.10.10.50.2-0.2-0.1-0.2-0.30.1-0.0-0.2-0.2-0.30.7-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.60.20.3-0.0-0.10.1-0.3-0.1-0.0-0.1-0.3-0.8-0.1
Delta time to tail flick, test, before/after SA0.10.10.50.2-0.2-0.1-0.2-0.50.2-0.3-0.1-0.2-0.20.7-0.2
Ambulatory time before self-admin0.10.10.90.10.2-0.10.11.0-0.30.20.10.2-0.1-0.70.1
Ambulatory time after self-admin4.95.48.62.42.22.12.62.92.21.92.52.62.31.02.6
Total heroin consumption0.50.62.0-1.1-0.9-1.1-0.6-1.4-0.5-0.9-0.5-0.5-0.50.0-0.6
Area under the delay curve0.30.31.10.40.50.50.5-0.50.80.20.30.50.81.10.5
Delay disc. indifference point, 0s delay0.40.42.20.50.30.60.5-0.20.80.40.30.50.81.50.5
Delay disc. indifference point, 16s delay0.10.10.30.10.30.20.1-0.50.3-0.10.00.10.10.50.1
Delay disc. indifference point, 2s delay0.10.10.20.10.20.10.3-0.20.40.20.30.30.50.50.2
Delay disc. indifference point, 24s delay0.40.42.30.40.50.40.5-0.60.80.20.30.50.41.50.6
Delay disc. indifference point, 4s delay0.20.21.0-0.3-0.1-0.2-0.4-1.0-0.1-0.3-0.4-0.4-0.1-0.1-0.4
Delay disc. indifference point, 8s delay0.70.72.20.60.70.70.8-0.21.20.60.50.81.11.50.8
Delay discount exponential model param0.30.31.3-0.4-0.4-0.4-0.40.6-0.8-0.1-0.3-0.4-0.7-1.1-0.4
Delay discount hyperbolic model param0.30.30.7-0.3-0.5-0.4-0.40.5-0.8-0.3-0.3-0.4-0.7-0.8-0.4
Fecal boli incidents, locomotor time 10.30.30.50.50.40.40.60.10.60.60.70.60.5-0.10.6
Change in fecal boli incidents, locomotor task1.41.33.6-1.0-0.7-1.0-1.0-1.0-1.1-1.9-1.0-1.0-1.2-1.3-1.1
Time >=10cm from walls, locomotor time 10.60.61.21.01.10.90.80.90.50.50.70.70.6-0.80.8
Bouts of movement, locomotor time 10.40.41.70.40.10.40.4-1.10.70.60.20.30.71.30.3
Total resting periods, locomotor time 10.30.41.60.40.10.40.3-1.10.70.50.20.20.61.30.3
Rest time, locomotor task time 10.20.20.4-0.2-0.5-0.4-0.5-0.1-0.40.3-0.6-0.5-0.60.3-0.5
Distance moved, locomotor task time 10.20.30.40.30.50.60.50.10.60.60.60.50.70.50.6
Vertical activity count, locomotor time 10.60.62.5-0.7-0.4-0.6-0.70.1-1.0-0.9-0.7-0.7-0.7-1.6-0.7
Time >=10cm from walls, locomotor time 20.40.40.9-0.5-0.9-0.5-0.7-0.1-0.4-0.6-0.7-0.7-0.61.0-0.7
Bouts of movement, locomotor time 20.30.31.8-0.10.50.10.1-1.1-0.10.40.00.2-0.1-1.30.0
Total resting periods, locomotor time 20.30.30.90.30.70.40.4-0.70.20.60.40.60.2-1.00.4
Rest time, locomotor task time 22.22.54.22.11.81.81.71.61.51.51.61.61.40.01.7
Distance moved, locomotor task time 20.91.01.9-1.4-1.1-1.1-1.1-1.2-1.0-0.3-1.1-1.2-0.70.2-1.0
Vertical activity count, locomotor time 21.82.03.2-1.7-1.8-1.5-1.6-0.7-1.4-1.1-1.6-1.5-1.30.4-1.6
Weight adjusted by age0.40.42.20.60.20.70.50.40.90.30.30.50.41.50.5
Seeking ratio, delayed vs. immediate footshock0.80.91.50.80.81.01.01.21.10.71.01.01.00.91.0
Locomotion in novel chamber0.20.20.5-0.4-0.4-0.2-0.60.4-0.7-0.3-0.5-0.5-0.7-0.4-0.6
Locomotion in novel chamber post-restriction0.10.11.4-0.10.1-0.20.00.0-0.2-0.30.0-0.00.1-1.20.0
Progressive ratio0.20.31.0-0.6-0.1-0.5-0.2-0.1-0.6-0.7-0.3-0.2-0.7-1.0-0.2
Food seeking constrained by brief footshock0.60.71.6-1.2-0.8-1.1-0.6-1.2-0.8-0.9-0.8-0.7-0.6-0.4-0.6
Seeking ratio, punishment vs. effort0.10.20.7-0.2-0.4-0.3-0.3-0.9-0.10.0-0.4-0.40.20.6-0.3
Run reversals in cocaine runway, females3.23.14.01.81.91.72.02.01.81.31.91.91.80.82.0
Run reversals in cocaine runway, males0.20.21.8-0.30.1-0.3-0.20.1-0.5-0.3-0.3-0.2-0.6-1.3-0.2
Latency to leave start box in cocaine runway0.20.20.3-0.5-0.4-0.3-0.50.0-0.6-0.3-0.5-0.5-0.5-0.3-0.5
Latency to leave start box in cocaine runway, F0.20.21.0-0.4-0.2-0.1-0.30.8-0.7-0.1-0.3-0.3-0.4-1.0-0.3
Latency to leave start box in cocaine runway, M0.10.10.50.0-0.00.0-0.1-0.70.10.0-0.2-0.20.10.7-0.1
Cd content in liver2.12.35.0-1.5-1.0-1.5-1.3-0.6-1.9-1.7-1.4-1.4-1.7-2.2-1.3
Co content in liver0.10.21.40.30.20.20.41.20.1-0.00.30.30.1-0.10.4
Cu content in liver0.80.91.41.00.90.81.20.81.00.81.11.11.00.41.2
Fe content in liver0.40.51.1-0.9-1.1-0.9-0.60.1-0.6-0.8-0.6-0.7-0.90.3-0.6
K content in liver0.70.70.90.80.80.70.90.01.00.90.90.91.00.50.9
Mg content in liver0.20.20.60.20.10.00.2-0.80.50.40.30.30.40.70.2
Mn content in liver1.41.72.0-1.4-1.3-1.4-1.2-1.1-1.4-1.4-1.4-1.4-1.4-0.6-1.2
Na content in liver1.41.53.0-1.2-1.1-1.2-1.3-1.7-1.2-0.8-1.3-1.3-1.2-0.7-1.3
Rb content in liver0.20.21.1-0.20.1-0.4-0.2-1.0-0.3-0.5-0.2-0.2-0.1-0.9-0.2
Se content in liver0.40.51.50.60.80.60.70.40.51.20.70.60.8-0.60.7
Sr content in liver1.91.73.51.31.91.31.30.70.81.11.31.31.4-1.41.3
Zn content in liver0.50.62.8-0.7-0.3-0.7-0.6-0.3-1.0-0.5-0.5-0.6-0.8-1.7-0.6