Hub : Genes

Abca6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000046890 0.26 0.07 0.0e+00 0.25 0.3 0.33 0.27 8.4e-28 4.1e-34 3.2e-37 1.2e-29
2 BLA gene expression ENSRNOG00000046890 0.15 0.06 4.9e-08 0.12 0.11 0.1 0.12 7.7e-07 2.6e-06 4.4e-06 9.4e-07
3 Brain gene expression ENSRNOG00000046890 0.18 0.06 0.0e+00 0.22 0.21 0.22 0.22 9.7e-20 2.4e-19 3.8e-20 2.4e-20
4 Liver gene expression ENSRNOG00000046890 0.22 0.07 0.0e+00 0.17 0.15 0.16 0.16 2.8e-18 9.2e-17 6.0e-17 9.1e-18
5 Liver intron excision ratio chr10:95209800:95211144 0.07 0.03 7.5e-08 0.08 0.06 0.07 0.03 1.5e-09 3.1e-07 1.6e-08 2.3e-04
6 Liver intron excision ratio chr10:95209800:95211153 0.07 0.03 3.7e-07 0.05 0.04 0.03 0.01 5.8e-06 8.1e-06 9.4e-05 4.5e-02
7 Liver intron excision ratio chr10:95209800:95211289 0.21 0.07 0.0e+00 0.22 0.23 0.24 0.2 3.6e-24 7.5e-25 4.5e-26 8.0e-22
8 Liver mRNA stability ENSRNOG00000046890 0.32 0.08 0.0e+00 0.31 0.32 0.33 0.32 1.8e-35 1.1e-36 3.7e-37 7.5e-37
9 NAcc gene expression ENSRNOG00000046890 0.15 0.08 3.8e-09 0.12 0.12 0.09 0.12 4.8e-09 5.2e-09 4.2e-07 1.6e-09
10 OFC gene expression ENSRNOG00000046890 0.15 0.09 9.0e-03 0.04 0.04 0.07 0 3.3e-02 4.3e-02 8.0e-03 3.1e-01
11 PL gene expression ENSRNOG00000046890 0.2 0.08 2.4e-12 0.17 0.17 0.16 0.04 2.6e-13 5.7e-13 1.7e-12 2.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail5.517.723.1-4.7-4.2-4.4-2.3-4.3-4.84.6-2.2-4.7-4.5-4.5
BMI without tail4.18.614.3-3.4-2.6-2.6-2.9-2.6-3.03.8-2.6-2.9-2.6-2.9
Body weight6.929.137.6-6.1-5.7-5.4-4.0-5.7-6.15.8-3.4-5.1-5.3-5.9
Epididymis fat weight4.29.914.0-3.2-3.6-3.4-1.5-3.7-3.72.6-1.3-3.7-3.0-3.6
Glucose0.10.10.4-0.70.1-0.20.30.1-0.50.0-0.3-0.3-0.5-0.2
Heart weight3.95.69.4-3.0-2.1-1.7-2.8-2.1-2.22.9-3.1-0.4-2.3-2.2
Left kidney weight0.61.62.8-1.6-1.3-1.2-1.1-1.3-1.31.7-0.6-1.0-1.3-1.3
Right kidney weight0.30.91.6-0.9-1.1-0.9-0.7-1.2-1.31.1-0.3-0.4-0.7-1.1
Tail length1.44.112.3-2.3-1.6-1.4-3.5-1.6-1.92.3-2.6-0.8-1.1-1.8
Length with tail1.45.27.1-2.7-2.5-2.1-2.4-2.5-2.62.3-1.7-1.4-2.1-2.5
Length without tail0.51.01.7-0.7-1.3-1.00.7-1.3-1.20.10.8-0.7-1.2-1.2
Liver weight, left0.40.60.90.60.90.80.60.90.7-0.90.80.50.90.9
Liver weight, right0.71.16.31.00.30.31.70.3-0.1-1.02.5-0.50.40.3
Parametrial fat weight1.12.23.71.21.71.90.31.71.2-1.80.31.51.81.7
Retroperitoneal fat weight2.78.812.1-3.1-3.3-3.4-1.6-3.4-3.22.7-1.2-3.2-3.2-3.5
Intraocular pressure3.65.09.3-2.8-2.3-2.0-2.0-2.3-2.23.0-2.2-1.4-1.7-2.3
Extensor digitorum longus weight0.62.54.8-1.8-1.6-1.80.0-1.7-1.80.9-0.4-2.2-1.8-1.7
Soleus weight0.20.53.0-0.80.50.3-0.90.40.10.2-1.70.60.40.4
Tibialis anterior weight0.41.21.8-1.3-1.2-1.4-0.6-1.2-1.31.0-1.0-1.2-0.6-1.1
Tibia length2.05.68.7-2.9-2.5-2.4-2.1-2.4-2.32.4-1.9-2.0-2.3-2.6
Number of licking bursts0.30.41.1-0.8-0.6-0.2-1.0-0.6-0.20.4-0.9-0.30.2-0.6
Food consumed during 24 hour testing period0.91.13.80.5-0.5-0.81.7-0.5-0.2-0.01.9-1.9-0.1-0.5
Times rat made contact with spout0.70.91.3-0.8-1.1-1.0-0.7-1.1-0.71.0-0.2-1.1-0.9-1.1
Mean time between licks in bursts0.91.32.8-1.7-1.4-0.9-0.9-1.4-0.70.9-1.4-0.7-0.7-1.3
Mean num. licks in bursts0.20.20.70.4-0.0-0.40.7-0.0-0.30.20.8-0.3-0.6-0.0
Std. dev. time between licks in bursts0.30.41.2-0.1-0.6-0.41.1-0.60.1-0.21.0-0.8-0.4-0.5
Water consumed over 24 hours1.21.46.11.30.1-0.22.30.10.7-0.72.5-1.20.40.3
Indifference point 0 sec2.43.99.2-1.8-1.8-2.2-1.5-1.8-2.13.0-0.9-1.5-2.3-1.9
Indifference point AUC0.20.20.7-0.5-0.1-0.5-0.1-0.0-0.80.4-0.2-0.6-0.7-0.3
Indifference point function ln k0.20.30.80.50.40.70.40.40.90.10.30.50.40.6
Indifference point function log k0.20.30.80.50.40.70.40.40.90.10.30.50.40.6
Delay discounting total patch changes 0 sec2.43.99.1-1.8-1.8-2.1-1.5-1.9-2.13.0-0.8-1.6-2.3-1.9
Delay discounting total patch changes 12 sec0.70.92.1-0.8-0.7-1.1-0.4-0.6-1.41.4-0.2-0.6-1.4-0.9
Delay discounting total patch changes 18 sec2.43.25.1-1.8-1.7-2.2-0.2-1.6-2.12.2-0.4-2.0-2.2-1.7
Delay discounting total patch changes 24 sec1.11.43.8-1.3-0.7-0.9-1.6-0.6-1.22.0-1.4-0.7-1.1-0.9
Delay discounting total patch changes 6 sec4.06.110.6-2.6-2.4-2.6-1.8-2.2-2.93.2-1.7-2.0-2.9-2.4
Delay discounting time to switch 0 sec0.20.31.30.20.30.50.10.30.8-1.10.00.70.90.3
Delay discounting water rate 0 sec2.33.66.9-1.7-1.9-2.0-1.0-2.0-2.32.6-0.5-1.8-2.3-2.0
Delay discounting water rate 12 sec2.53.76.4-1.3-2.2-2.2-0.0-2.2-2.52.10.4-2.2-2.1-2.0
Delay discounting water rate 18 sec0.30.41.60.70.30.41.30.30.1-0.21.30.0-0.10.2
Delay discounting water rate 24 sec0.30.31.30.90.20.41.10.10.2-0.11.1-0.10.10.3
Delay discounting water rate 6 sec0.30.51.70.4-0.4-0.51.0-0.5-0.50.31.3-0.9-0.4-0.4
Locomotor activity0.40.71.7-1.0-0.7-0.7-0.3-0.7-0.91.3-0.7-0.8-0.9-0.7
Locomotor testing distance1.42.44.9-1.6-1.7-1.5-0.6-1.6-1.62.2-0.9-1.3-1.7-1.6
Locomotor testing rearing5.18.111.7-2.7-3.2-3.1-0.7-3.1-3.33.3-0.7-2.7-3.4-3.2
Light reinforcement 10.71.36.80.60.1-0.62.60.0-0.40.12.3-1.0-0.20.1
Light reinforcement 20.10.10.50.10.50.20.20.40.3-0.2-0.20.00.70.3
Reaction time number correct0.81.21.81.11.21.30.81.21.1-1.00.31.11.31.3
Reaction time mean minus median0.70.92.51.01.00.70.91.00.8-1.60.60.41.10.8
Reaction time mean minus median AUC2.73.55.22.12.01.71.42.01.8-2.21.01.52.32.0
Reaction time num false alarms0.50.73.8-0.50.20.2-1.40.30.01.1-2.00.70.20.2
Reaction time num false alarms AUC0.81.22.40.41.21.0-1.01.20.80.2-1.61.41.11.1
Reaction time trials correct on left0.81.21.81.11.21.30.81.21.1-1.00.31.11.31.3
Reaction time trials on left1.01.42.11.21.31.40.91.31.2-1.10.31.21.41.4
Reaction time mean0.40.51.90.80.60.40.90.50.6-1.40.90.50.70.4
Reaction time mean AUC0.30.41.50.70.40.20.90.40.5-1.21.00.30.60.3
Median of all reaction times0.30.41.30.60.40.20.90.30.5-1.20.90.40.40.3
Reaction time omissions3.44.57.32.72.01.72.02.12.0-2.51.71.62.62.1
Reaction time false alarm rate0.40.52.6-0.40.1-0.0-1.40.2-0.00.9-1.60.40.00.1
Reaction time premature initiation rate1.52.03.4-1.3-1.3-1.3-1.1-1.3-1.71.8-0.7-1.3-1.9-1.4
Reaction time premature initiations0.10.20.6-0.2-0.2-0.2-0.4-0.3-0.70.8-0.3-0.3-0.6-0.3
Std. dev. reaction times1.62.24.71.71.51.21.31.51.4-2.21.21.11.61.4
Reaction time trials completed1.01.42.11.21.31.40.91.31.2-1.10.31.21.41.4
Reaction time trials AUC0.81.21.81.11.21.30.91.21.1-1.00.41.11.31.3
Social response proportion0.70.81.80.70.80.9-0.30.80.9-1.0-0.51.31.30.9
Social responses0.30.40.91.00.60.40.80.50.8-0.40.80.20.70.6
Social time1.11.42.90.51.31.4-0.31.31.1-1.2-0.91.71.51.2
Conditioned locomotion0.10.10.20.10.30.4-0.20.30.10.1-0.20.40.40.2
Cocaine response after cond. corrected0.60.73.3-0.30.30.4-1.50.30.10.1-1.81.00.40.3
Cocaine response after cond. not corrected0.70.84.3-0.60.20.3-1.70.2-0.00.2-2.10.90.30.1
Cocaine response before conditioning0.10.10.2-0.4-0.2-0.30.3-0.2-0.30.30.1-0.4-0.3-0.4
Saline control response2.33.05.7-0.8-1.8-2.10.7-1.8-2.11.81.0-2.4-1.8-1.8
Condit. Reinf. active minus inactive responses1.01.35.1-1.20.00.3-2.10.0-0.51.1-2.31.2-0.20.0
Condit. Reinf. active-inactive response ratio1.21.24.7-1.10.20.6-2.20.2-0.40.7-2.21.4-0.20.2
Condit. Reinf. active responses0.60.93.2-0.70.30.4-1.60.3-0.31.1-1.81.30.20.2
Condit. Reinf. inactive responses0.10.10.40.30.0-0.30.50.0-0.00.70.3-0.10.2-0.1
Condit. Reinf. lever presses0.40.51.5-0.6-0.6-0.6-0.9-0.6-0.91.2-0.6-0.2-0.5-0.6
Condit. Reinf. lever reinforcers received0.60.82.8-0.70.20.2-1.60.2-0.51.1-1.71.1-0.00.0
Pavlov. Cond. lever latency0.30.41.0-0.3-0.8-0.70.6-0.8-0.3-0.30.5-1.0-0.6-0.8
Pavlov. Cond. magazine entry latency0.10.10.6-0.50.0-0.2-0.50.00.10.2-0.8-0.2-0.20.1
Pavlov. Cond. change in total contacts0.20.21.1-0.30.20.2-0.70.20.30.5-1.10.50.40.3
Pavlov. Cond. index score0.30.41.7-0.40.50.4-1.10.50.20.4-1.30.60.30.4
Pavlov. Cond. latency score0.30.41.9-0.50.30.3-1.10.30.20.5-1.40.50.20.3
Pavlov. Cond. lever contacts0.20.30.50.60.70.6-0.00.70.30.00.10.70.70.7
Pavlov. Cond. magazine entry number0.20.31.00.80.10.40.50.10.3-0.51.00.40.60.1
Pavlov. Cond. intertrial magazine entries1.72.23.91.91.61.60.61.61.2-1.31.01.62.01.5
Pavlov. Cond. lever-magazine prob. diff.0.30.41.8-0.40.50.4-1.00.50.30.4-1.30.70.30.5
Pavlov. Cond. response bias0.30.40.70.40.80.6-0.30.80.3-0.1-0.20.80.60.8
Conditioned reinforcement - actives2.22.23.51.31.51.90.91.51.5-1.30.61.61.61.9
Conditioned reinforcement - inactives0.30.31.00.20.50.6-1.00.50.60.1-0.80.60.20.6
Conditioned locomotion0.40.41.3-0.7-0.40.0-1.0-0.4-0.50.8-1.10.7-0.2-0.2
Intermittent access intake day 1-15 change0.40.41.0-0.4-0.7-0.8-0.0-0.8-0.90.40.1-0.4-1.0-0.7
Intermittent access intake escalation0.20.20.5-0.2-0.5-0.50.1-0.6-0.40.10.0-0.2-0.7-0.4
Intermittent access intake escalation 20.10.10.20.2-0.1-0.00.4-0.1-0.3-0.40.40.4-0.2-0.1
Intermitt. access day 1 inactive lever presses1.71.83.9-1.3-1.3-1.2-2.0-1.3-1.21.8-0.9-0.7-1.1-1.5
Intermitt. access day 15 inactive lever presses0.30.30.6-0.7-0.5-0.6-0.3-0.5-0.70.40.2-0.6-0.8-0.7
Intermitt. access escalation Index0.40.31.20.30.50.6-0.30.61.1-0.5-0.20.60.50.5
Intermittent access day 1 total infusions0.10.10.30.00.30.30.50.3-0.00.30.20.0-0.00.4
Intermittent access day 15 total infusions0.10.10.2-0.2-0.2-0.10.3-0.3-0.40.30.10.1-0.5-0.0
Intermittent access terminal intake (last 3 days)0.20.30.60.50.50.60.50.40.3-0.40.40.80.30.6
Intermittent access total infusions0.10.10.40.1-0.00.00.6-0.0-0.30.30.50.0-0.30.2
Intermittent access day 1 locomotion0.30.30.7-0.6-0.7-0.3-0.2-0.6-0.70.8-0.3-0.2-0.6-0.4
Intermittent access day 15 total locomotion0.20.20.8-0.5-0.30.0-0.4-0.3-0.40.5-0.40.8-0.9-0.1
Intermittent access total locomotion0.60.71.6-0.8-1.0-0.70.1-0.9-1.31.2-0.0-0.4-1.2-0.7
Intermittent access standard deviation0.30.31.0-0.7-0.5-0.40.2-0.6-0.50.6-0.2-0.3-1.0-0.4
Cocaine induced anxiety0.10.10.5-0.1-0.10.1-0.5-0.1-0.2-0.1-0.00.7-0.2-0.1
Post-drug Anxiety0.10.10.50.2-0.20.0-0.1-0.2-0.2-0.50.30.70.0-0.1
Baseline Anxiety0.20.20.70.4-0.4-0.40.7-0.20.2-0.30.8-0.70.4-0.3
Lifetime Intake0.10.10.50.20.20.20.70.2-0.00.40.40.2-0.00.3
Incentive Sensitization - Responses0.40.41.5-0.7-0.3-0.1-1.2-0.3-0.50.5-1.00.5-0.4-0.2
Incentive Sensitization - Breakpoint0.40.41.5-0.7-0.4-0.1-1.2-0.4-0.50.4-1.00.5-0.4-0.3
Progressive ratio test 1 active lever presses1.31.33.0-0.4-1.1-1.21.0-1.1-1.41.11.1-1.7-1.1-0.9
Progressive ratio test 1 breakpoint1.41.53.3-0.6-1.2-1.30.7-1.2-1.51.40.8-1.8-1.2-1.0
Progressive ratio test 1 inactive lever presses0.20.31.00.4-0.2-0.20.9-0.10.10.51.0-0.80.10.0
Progressive ratio test 2 active lever presses0.50.51.0-0.9-0.8-0.6-0.3-0.9-1.00.9-0.3-0.4-0.9-0.6
Progressive ratio test 2 breakpoint0.70.81.6-1.0-1.0-0.8-0.4-1.0-1.30.9-0.2-0.6-1.1-0.8
Progressive ratio test 2 inactive lever presses0.20.20.7-0.20.50.6-0.40.40.20.2-0.50.80.10.6
Total sessions with >9 infusions0.30.41.8-0.1-0.2-0.41.3-0.2-0.50.70.8-0.5-0.6-0.1
Short access day 1 total inactive lever presses0.10.10.2-0.3-0.3-0.30.2-0.4-0.30.50.2-0.2-0.4-0.3
Short access day 10 total inactive lever presses0.20.21.1-0.2-0.1-0.1-1.0-0.1-0.20.4-0.70.20.2-0.2
Short access day 1 total infusions0.40.41.2-0.1-0.4-0.61.1-0.5-0.20.80.7-0.8-0.4-0.4
Short access day 10 total infusions0.10.10.40.30.1-0.10.60.20.00.60.5-0.5-0.20.2
Short access total infusions0.20.21.00.30.20.01.00.20.20.50.5-0.10.00.3
Short access day 1 locomotion0.60.61.3-0.2-0.8-0.90.6-0.7-0.60.90.8-1.2-1.0-0.7
Short access day 10 total locomotion0.40.41.1-0.8-0.5-0.3-0.5-0.5-0.61.0-1.0-0.2-0.7-0.4
Short access total locomotion0.60.61.0-0.4-0.7-0.80.9-0.7-0.60.90.7-1.0-0.9-0.7
Compulsive drug intake0.40.41.20.10.40.5-1.00.40.6-0.1-0.91.10.80.4
One hour access (0.3 mA shock)0.30.41.00.50.70.70.20.80.3-0.10.01.00.50.9
One hour access (shock baseline)0.40.40.70.70.70.70.80.70.3-0.60.60.60.60.8
Number of responses in last shaping day1.21.23.2-0.9-0.9-1.20.6-0.9-1.20.80.7-1.8-1.6-1.0
Context. condit. distance diff. score0.10.10.40.1-0.0-0.3-0.1-0.0-0.40.00.1-0.3-0.7-0.2
Locomotion velocity, session 10.10.10.2-0.2-0.2-0.10.3-0.3-0.20.40.1-0.40.0-0.2
Locomotion distance, session 10.30.41.70.3-0.0-0.41.2-0.1-0.30.41.3-0.3-0.5-0.1
Locomotion velocity, session 20.00.00.30.2-0.10.0-0.1-0.10.10.50.4-0.10.1-0.1
Locomotion distance, session 20.50.72.90.80.60.31.70.50.4-0.11.70.10.20.5
Locomotion velocity, session 31.11.34.7-0.1-0.5-1.02.2-0.5-0.80.51.8-1.4-1.1-0.5
Locomotion distance, session 30.40.51.50.50.80.51.20.80.4-0.60.70.50.30.6
Stereotopy head waving bouts, day 31.51.76.61.60.40.52.40.40.9-1.32.6-0.40.70.6
Stereotopy head waving duration, day 30.40.51.60.70.00.21.30.00.7-0.61.2-0.40.40.2
Locomotion velocity, session 70.70.81.21.11.10.80.51.10.9-0.70.80.60.90.9
Locomotion distance, session 70.30.41.00.60.80.70.10.80.5-0.30.11.00.50.6
Stereotopy head waving bouts, day 70.70.82.11.00.50.71.40.41.0-0.91.10.40.80.7
Stereotopy head waving duration, day 71.51.83.11.51.01.21.81.01.6-1.61.30.61.41.3
Locomotion velocity, session 80.30.40.8-0.5-0.5-0.6-0.7-0.5-0.90.8-0.4-0.3-0.6-0.5
Locomotion distance, session 80.20.31.30.60.4-0.10.90.4-0.00.21.1-0.1-0.50.3
Degree of sensitization distance0.10.10.50.2-0.20.1-0.7-0.20.10.3-0.20.20.2-0.1
Degree of sensitization stereotypy0.00.00.20.1-0.00.10.5-0.10.4-0.10.20.10.20.1
Condit. Reinf. active minus inactive responses1.11.22.0-1.4-1.3-1.0-0.7-1.3-1.01.2-1.0-0.5-1.0-1.3
Condit. Reinf. active-inactive response ratio0.00.10.10.0-0.3-0.10.1-0.30.3-0.3-0.30.00.2-0.3
Condit. Reinf. active responses1.01.32.2-1.5-1.1-0.9-1.0-1.1-1.01.5-1.3-0.4-1.0-1.1
Condit. Reinf. inactive responses0.70.92.1-1.3-0.5-0.5-1.2-0.5-1.01.5-1.2-0.0-0.9-0.5
Incentive salience index mean0.20.20.5-0.6-0.6-0.5-0.1-0.7-0.30.5-0.3-0.2-0.3-0.7
Condit. Reinf. lever presses0.20.20.4-0.2-0.6-0.60.6-0.60.10.10.6-0.5-0.4-0.6
Time in familiar zone, hab. session 10.60.61.00.60.90.7-0.30.91.0-0.7-0.80.90.70.9
Time in novel zone, hab. session 10.50.50.9-0.3-0.7-0.60.6-0.7-1.00.60.9-0.6-0.6-0.7
Total zone transitions, hab. session 10.50.71.3-0.5-0.9-1.10.1-1.0-0.71.00.5-1.1-1.0-0.9
Total locomotion distance, hab. session 11.11.52.5-0.7-1.3-1.40.9-1.4-1.11.11.2-1.6-1.3-1.3
Locomotion velocity, hab. session 11.01.52.5-0.9-1.3-1.40.7-1.4-1.01.11.0-1.6-1.2-1.3
Time in familiar zone, hab. session 21.01.03.1-1.3-0.7-0.7-1.5-0.7-0.81.1-1.8-0.1-0.6-0.7
Time in novel zone, hab. session 23.63.66.22.41.81.42.31.71.7-2.12.51.01.71.7
Total zone transitions, hab. session 20.20.30.9-0.2-0.3-0.80.6-0.4-0.00.60.4-1.0-0.3-0.4
Total locomotion distance, hab. session 20.91.23.3-0.1-0.7-1.11.8-0.8-0.40.51.6-1.7-0.8-0.8
Locomotion velocity, hab. session 20.91.23.7-0.1-0.7-1.11.9-0.7-0.40.41.7-1.7-0.8-0.8
Novel to familiar place preference ratio2.12.27.9-1.6-0.8-0.5-2.8-0.8-0.91.6-2.70.3-1.0-1.0
Novelty place preference1.71.86.7-1.4-0.7-0.3-2.6-0.6-0.71.4-2.50.4-0.8-0.8
Time in novel zone, NPP test1.41.55.8-1.3-0.6-0.3-2.4-0.5-0.71.3-2.30.3-0.8-0.7
Total zone transitions, NPP test0.40.62.60.50.1-0.41.6-0.00.20.31.5-0.9-0.20.1
Total locomotion distance, NPP test1.11.57.20.6-0.3-0.72.5-0.4-0.40.22.7-1.2-0.6-0.3
Locomotion velocity, NPP test1.21.75.90.2-0.7-1.02.3-0.8-0.70.62.4-1.6-1.1-0.7
Pavlov. Cond. lever latency1.82.34.31.62.01.40.72.11.3-1.60.71.41.41.8
Pavlov. Cond. magazine entry latency0.30.40.9-0.4-0.9-0.8-0.1-0.9-0.60.5-0.1-0.6-0.5-0.9
Pavlov. Cond. change in total contacts1.61.72.5-1.4-1.6-1.2-1.1-1.6-1.41.4-0.9-0.9-1.2-1.5
Pavlov. Cond. index score0.91.12.1-1.0-1.4-1.1-0.5-1.5-1.11.1-0.4-0.8-0.9-1.3
Pavlov. Cond. latency score1.11.42.6-1.1-1.6-1.2-0.6-1.6-1.21.2-0.5-1.0-1.0-1.5
Pavlov. Cond. lever contacts1.41.73.0-1.3-1.7-1.3-0.6-1.7-1.11.4-0.6-1.2-1.1-1.6
Pavlov. Cond. magazine entry number0.10.20.40.20.60.4-0.00.60.5-0.20.00.20.40.6
Pavlov. Cond. intertrial magazine entries3.33.910.8-2.8-1.4-0.8-2.9-1.4-1.42.6-3.3-0.2-1.3-1.3
Pavlov. Cond. lever-magazine prob. diff.0.70.81.6-0.9-1.3-0.9-0.4-1.3-0.91.0-0.3-0.7-0.7-1.2
Pavlov. Cond. response bias0.30.40.8-0.6-0.9-0.6-0.2-0.9-0.50.6-0.3-0.4-0.5-0.8
Bone: apparent density4.87.912.62.73.13.10.43.13.2-2.50.23.63.43.1
Bone surface4.27.414.51.82.73.0-1.12.73.2-1.8-1.73.83.82.8
Bone volume3.86.413.21.62.72.8-1.22.72.8-1.5-1.73.63.42.6
Bone: connectivity density4.67.211.42.82.92.81.12.92.9-2.41.23.23.42.8
Bone: cortical apparent density1.82.38.90.4-0.6-1.32.4-0.6-1.1-0.23.0-1.7-1.7-0.7
Bone: cortical area0.60.92.4-1.1-0.7-1.1-0.6-0.7-1.21.6-0.8-0.6-1.0-0.8
Bone: cortical porosity0.80.82.8-0.10.40.8-1.40.40.70.2-1.71.21.10.4
Bone: cortical porosity0.80.84.4-0.7-0.10.3-1.6-0.00.20.7-2.10.70.6-0.0
Bone: cortical thickness3.96.412.0-0.7-2.1-2.92.7-2.0-2.61.63.0-3.5-3.4-2.1
Bone: cortical thickness1.31.57.40.90.1-0.32.70.1-0.1-0.42.7-1.0-0.50.1
Bone: cortical tissue density1.62.18.30.4-0.6-1.22.4-0.6-1.0-0.22.9-1.7-1.7-0.7
Bone: elastic displacement0.30.41.30.70.40.21.10.40.5-0.11.1-0.3-0.20.4
Bone: elastic work0.10.10.40.00.1-0.10.60.20.10.40.4-0.4-0.2-0.0
Bone: endosteal estimation4.29.039.0-1.71.01.5-5.71.01.20.8-6.23.32.60.8
Bone: endosteal perimeter4.28.739.2-1.50.91.5-5.51.01.11.1-6.33.32.50.8
Bone: final force0.20.20.9-0.20.30.2-0.90.30.30.1-1.00.60.50.2
Bone: final moment0.20.30.9-0.10.40.3-0.90.40.40.1-1.00.60.50.3
Bone: marrow area4.18.737.8-1.70.91.5-5.61.01.20.8-6.13.32.50.8
Bone: maximum diameter1.52.78.1-0.21.41.3-2.21.41.00.0-2.82.21.91.3
Bone: maximum force0.30.52.3-0.60.0-0.1-1.20.10.10.6-1.50.70.4-0.0
Bone: maximum moment0.30.52.5-0.50.1-0.0-1.30.10.30.5-1.60.80.40.0
Bone: minimum diameter2.64.823.8-1.80.20.5-4.10.30.01.6-4.92.11.10.1
Bone: periosteal estimation2.24.521.5-1.60.50.6-4.10.60.41.2-4.62.11.40.3
Bone: periosteal perimeter2.03.316.9-1.7-0.00.3-3.40.0-0.11.4-4.11.50.6-0.1
Bone: post-yield work0.50.62.7-0.40.20.3-1.30.20.10.3-1.71.10.70.2
Bone: stiffness0.10.20.8-0.30.2-0.0-0.80.30.0-0.1-0.90.60.50.2
Bone: tissue strength0.80.83.51.10.3-0.11.70.30.6-0.51.9-0.2-0.00.4
Bone: trabecular number5.48.412.23.13.13.01.23.13.2-2.71.13.43.53.1
Bone: trabecular spacing4.15.38.1-2.2-2.7-2.3-0.5-2.7-2.61.9-0.3-2.7-2.9-2.6
Bone: trabecular thickness1.41.73.90.71.51.5-0.71.51.1-0.5-0.92.01.61.4
Bone: trabecular tissue density1.21.73.1-0.9-1.4-1.40.9-1.4-1.60.60.8-1.6-1.8-1.3
Breakpoint value in progressive ratio session0.40.51.6-0.3-0.5-0.80.8-0.7-0.60.20.8-1.3-0.1-0.6
Distance traveled before self-admin0.30.30.5-0.7-0.5-0.5-0.6-0.6-0.30.3-0.5-0.5-0.7-0.6
Distance traveled after self-admin0.00.00.2-0.1-0.1-0.3-0.2-0.1-0.20.0-0.2-0.4-0.2-0.2
Delta time in closed arm before/after self-admin1.91.93.61.21.51.90.21.51.4-1.4-0.01.81.21.6
Delta time in open arm before/after self-admin1.31.22.41.41.20.90.61.11.6-1.00.90.71.31.0
Diff in mean of infusions in LGA sessions0.91.01.4-1.0-1.2-1.10.2-1.2-1.20.70.0-1.2-1.1-1.2
Extinction: sum of active levers before priming0.40.41.7-0.8-0.1-0.2-1.0-0.30.00.4-1.30.00.8-0.3
Active lever presses in extinction session 60.10.10.20.3-0.0-0.10.3-0.10.20.10.40.20.5-0.2
Delta distance traveled before/after self-admin0.50.51.70.90.60.41.30.80.4-0.61.1-0.20.40.6
Delta ambulatory time before/after self-admin1.21.31.91.41.11.01.31.30.8-1.11.10.91.01.2
Time in closed arm before self-admin0.70.81.5-1.0-0.9-1.10.3-0.9-0.81.1-0.0-1.2-0.7-0.8
Time in closed arm after self-admin0.10.10.4-0.6-0.3-0.20.1-0.3-0.30.3-0.3-0.4-0.4-0.2
Time in open arm before self-admin0.70.81.5-0.8-1.0-0.8-0.2-1.0-1.20.3-0.3-1.0-1.1-1.1
Time in open arm after self-admin0.30.30.8-0.6-0.5-0.6-0.9-0.5-0.40.4-0.7-0.2-0.2-0.6
Sum of active levers in priming session hrs 5-60.30.30.5-0.7-0.4-0.6-0.3-0.5-0.10.5-0.6-0.7-0.6-0.5
Time to tail flick, vehicle, before self-admin0.40.41.6-0.6-0.4-0.3-1.3-0.4-0.80.2-0.60.0-1.0-0.5
Time to tail flick, vehicle, after self-admin0.50.62.6-0.30.00.6-1.40.20.3-0.0-1.61.00.40.1
Time to tail flick, test, before self-admin1.31.36.3-0.9-0.00.4-2.50.0-0.40.3-2.31.2-0.10.1
Time to tail flick, test, after self-admin0.50.51.70.20.40.7-1.30.50.30.0-1.01.20.60.5
Delta time to tail flick, vehicle, before/after SA1.81.83.41.51.21.50.41.31.6-1.20.11.71.81.4
Delta time to tail flick, test, before/after SA0.50.41.00.60.60.7-0.00.80.8-0.4-0.11.00.70.7
Ambulatory time before self-admin0.50.50.9-0.8-0.9-0.7-0.4-0.9-0.60.4-0.3-1.0-0.7-0.7
Ambulatory time after self-admin0.00.00.10.20.1-0.00.40.10.1-0.30.3-0.20.10.1
Total heroin consumption0.60.71.70.90.90.90.40.90.7-0.80.60.81.30.9
Area under the delay curve0.10.10.6-0.20.20.0-0.80.1-0.30.2-0.70.0-0.10.1
Delay disc. indifference point, 0s delay0.20.20.60.30.50.20.80.4-0.2-0.70.50.4-0.00.3
Delay disc. indifference point, 16s delay0.40.41.8-0.5-0.1-0.5-1.3-0.1-0.40.6-1.2-0.50.1-0.2
Delay disc. indifference point, 2s delay0.00.10.30.10.10.3-0.00.1-0.2-0.0-0.00.5-0.00.3
Delay disc. indifference point, 24s delay0.50.52.0-0.30.70.6-0.90.60.50.1-1.40.70.70.5
Delay disc. indifference point, 4s delay0.10.10.3-0.10.30.4-0.60.2-0.40.0-0.2-0.1-0.30.3
Delay disc. indifference point, 8s delay0.30.30.90.0-0.1-0.60.8-0.2-0.7-0.10.8-0.9-0.7-0.1
Delay discount exponential model param0.20.21.20.2-0.2-0.21.1-0.20.3-0.30.9-0.20.0-0.2
Delay discount hyperbolic model param0.20.21.00.2-0.2-0.21.0-0.20.4-0.30.8-0.20.1-0.2
Fecal boli incidents, locomotor time 10.80.82.30.90.81.00.10.80.9-0.7-0.11.51.01.2
Change in fecal boli incidents, locomotor task0.20.20.60.2-0.1-0.30.8-0.10.1-0.30.6-0.6-0.3-0.1
Time >=10cm from walls, locomotor time 10.10.10.30.30.3-0.10.50.30.3-0.10.50.10.50.2
Bouts of movement, locomotor time 10.80.92.1-0.8-0.8-1.0-0.7-0.8-1.10.8-0.3-0.9-1.4-0.9
Total resting periods, locomotor time 10.30.30.9-0.5-0.4-0.5-0.6-0.4-0.70.4-0.3-0.5-1.0-0.5
Rest time, locomotor task time 10.10.10.5-0.5-0.2-0.40.5-0.3-0.4-0.10.2-0.1-0.7-0.3
Distance moved, locomotor task time 10.50.51.8-0.1-0.8-0.60.2-0.8-0.70.40.7-1.3-0.6-0.7
Vertical activity count, locomotor time 10.70.71.8-0.4-1.1-0.70.2-1.0-1.10.60.6-1.3-0.6-0.9
Time >=10cm from walls, locomotor time 21.11.23.4-0.8-1.0-1.51.1-1.0-0.60.31.1-1.8-0.9-1.0
Bouts of movement, locomotor time 20.91.03.2-0.4-0.9-1.30.0-0.9-1.20.90.2-1.8-1.2-0.8
Total resting periods, locomotor time 20.60.62.1-0.2-0.7-1.00.2-0.7-0.90.70.3-1.4-1.1-0.5
Rest time, locomotor task time 22.73.14.91.52.12.20.52.11.6-2.10.12.01.62.1
Distance moved, locomotor task time 22.83.37.6-1.0-2.0-2.21.0-2.0-1.80.91.6-2.7-1.7-2.0
Vertical activity count, locomotor time 22.62.95.0-1.1-2.1-2.00.5-2.0-1.91.41.0-2.2-1.5-2.0
Weight adjusted by age3.74.16.0-2.4-2.2-2.2-1.1-2.3-2.01.7-1.3-2.4-2.1-2.2
Seeking ratio, delayed vs. immediate footshock3.64.16.3-2.5-2.1-2.0-1.4-2.2-1.92.0-1.7-2.1-2.0-2.2
Locomotion in novel chamber0.30.42.0-0.40.0-0.1-1.30.00.40.1-1.4-0.40.4-0.1
Locomotion in novel chamber post-restriction1.31.53.11.81.31.00.91.41.5-1.11.00.71.21.3
Progressive ratio0.50.62.1-0.10.60.6-1.00.40.5-0.4-1.50.71.10.5
Food seeking constrained by brief footshock0.20.30.8-0.40.10.5-0.90.10.5-0.2-0.90.70.20.1
Seeking ratio, punishment vs. effort0.20.20.8-0.3-0.4-0.30.2-0.3-0.40.40.7-0.3-0.9-0.5
Run reversals in cocaine runway, females4.24.16.4-2.2-2.4-2.4-0.7-2.1-2.21.0-0.2-2.5-2.4-2.5
Run reversals in cocaine runway, males0.80.84.2-0.9-0.2-0.1-2.1-0.1-0.60.5-1.60.2-0.4-0.3
Latency to leave start box in cocaine runway2.62.87.5-0.9-1.9-1.91.3-1.7-1.61.11.4-2.7-1.7-1.7
Latency to leave start box in cocaine runway, F7.48.212.8-2.4-3.3-3.3-0.2-3.2-3.42.60.4-3.6-3.3-3.3
Latency to leave start box in cocaine runway, M1.51.55.61.10.50.42.40.61.2-1.42.0-0.60.90.7
Cd content in liver2.02.23.91.61.61.51.21.61.6-2.01.01.41.11.6
Co content in liver0.20.31.4-0.30.30.4-1.20.30.0-0.3-1.00.5-0.10.2
Cu content in liver0.70.91.90.61.01.40.41.00.9-0.90.01.31.01.0
Fe content in liver0.40.41.10.80.60.40.70.61.1-0.70.60.30.50.6
K content in liver2.12.14.01.71.41.60.11.41.6-1.30.41.62.01.5
Mg content in liver5.25.47.82.82.52.31.52.52.4-2.41.72.02.62.4
Mn content in liver6.27.19.13.02.82.52.62.82.7-2.72.12.52.72.8
Na content in liver1.21.31.91.41.01.10.91.01.3-1.21.00.91.31.1
Rb content in liver0.30.31.00.60.20.30.90.20.6-0.91.0-0.00.40.2
Se content in liver0.30.40.90.70.60.50.90.60.1-0.60.80.20.60.5
Sr content in liver0.20.20.8-0.6-0.3-0.2-0.6-0.3-0.00.7-0.90.1-0.4-0.3
Zn content in liver4.04.47.01.92.42.60.62.42.4-1.70.32.22.52.4