Clasrp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000075144 0.06 0.06 1.8e-04 0.03 0.03 0.03 0.03 5.6e-04 8.5e-04 2.1e-04 2.9e-04
2 Adipose alternative polyA ENSRNOT00000081565 0.07 0.08 1.7e-04 0.03 0.02 0.03 0.03 2.9e-04 8.7e-04 1.4e-04 2.8e-04
3 Adipose isoform ratio ENSRNOT00000075144 0.02 0.02 2.1e-03 0.02 0.02 0.02 0.01 5.6e-03 1.3e-03 1.1e-03 7.3e-03
4 Adipose isoform ratio ENSRNOT00000081565 0.02 0.02 2.2e-03 0.02 0.02 0.02 0.02 5.1e-03 1.3e-03 1.4e-03 6.6e-03
5 Adipose mRNA stability ENSRNOG00000046000 0.03 0.02 4.4e-03 0.02 0.02 0.02 0.02 6.4e-03 3.2e-03 6.0e-03 5.2e-03
6 Brain alternative polyA ENSRNOT00000075144 0.08 0.06 3.0e-07 0.06 0.07 0.06 0.07 2.7e-06 7.1e-07 2.2e-06 3.6e-07
7 Brain alternative polyA ENSRNOT00000081565 0.08 0.06 2.5e-07 0.06 0.07 0.06 0.07 2.1e-06 5.7e-07 2.3e-06 2.5e-07
8 Brain isoform ratio ENSRNOT00000075144 0.04 0.03 5.7e-04 0.03 0.02 0.02 0.02 8.7e-04 3.1e-03 4.8e-03 2.9e-03
9 Brain isoform ratio ENSRNOT00000081565 0.04 0.03 4.0e-04 0.03 0.02 0.02 0.03 6.1e-04 2.4e-03 2.6e-03 2.2e-03
10 IL isoform ratio ENSRNOT00000075144 0.14 0.11 5.8e-03 0.1 0.07 0.08 0.1 1.9e-03 9.6e-03 6.5e-03 2.3e-03
11 IL isoform ratio ENSRNOT00000081565 0.14 0.11 7.6e-03 0.1 0.07 0.08 0.09 2.2e-03 1.0e-02 5.0e-03 3.7e-03
12 Liver gene expression ENSRNOG00000046000 0.03 0.02 5.3e-03 0 0.01 0 0 7.7e-02 4.8e-02 1.3e-01 1.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.72.12.9-1.31.3-1.21.4-1.6-1.71.7-1.41.4-1.41.4-1.6
BMI without tail0.81.62.2-1.41.4-0.81.3-1.4-1.21.3-1.01.0-1.51.5-1.4
Body weight0.83.44.2-1.91.9-1.71.8-2.0-2.02.1-1.71.7-1.81.8-1.9
Epididymis fat weight0.82.02.61.6-1.61.4-1.41.11.3-1.21.5-1.51.4-1.41.2
Glucose0.30.40.60.6-0.60.6-0.50.70.7-0.70.8-0.80.6-0.60.8
Heart weight3.55.06.1-2.42.4-2.52.3-2.0-2.22.2-2.22.2-2.12.1-2.1
Left kidney weight7.822.426.0-5.15.1-4.74.7-4.5-4.74.6-4.84.8-4.64.6-4.6
Right kidney weight6.217.619.6-4.44.4-4.44.2-4.0-4.24.1-4.14.1-4.14.1-4.1
Tail length0.00.10.3-0.50.5-0.00.2-0.4-0.40.4-0.10.1-0.30.3-0.4
Length with tail0.31.01.4-1.11.1-1.10.8-1.1-1.11.2-0.80.8-0.80.8-1.0
Length without tail0.40.81.5-0.80.8-1.20.7-1.0-1.21.2-0.90.9-0.50.5-0.9
Liver weight, left10.116.318.0-4.24.2-3.93.8-4.2-4.24.2-3.93.9-3.83.8-4.2
Liver weight, right2.84.66.0-2.32.4-1.91.9-2.3-2.42.4-2.02.0-1.71.7-2.3
Parametrial fat weight0.00.00.10.1-0.10.30.20.10.1-0.2-0.30.3-0.30.30.0
Retroperitoneal fat weight0.00.10.20.5-0.50.2-0.30.20.1-0.10.3-0.30.2-0.20.2
Intraocular pressure0.00.10.3-0.20.2-0.10.1-0.3-0.50.5-0.10.10.1-0.1-0.2
Extensor digitorum longus weight1.76.99.1-2.82.8-2.22.2-3.0-2.93.0-2.52.5-2.32.3-2.9
Soleus weight0.20.61.7-0.60.7-0.00.2-1.3-1.11.2-0.40.4-0.50.5-1.1
Tibialis anterior weight3.612.414.9-3.73.7-3.23.1-3.9-3.83.8-3.43.4-3.23.2-3.8
Tibia length0.30.81.1-0.90.9-1.00.9-0.6-0.70.7-0.90.9-1.01.0-0.7
Number of licking bursts2.32.74.1-1.51.5-1.41.5-1.7-1.51.5-1.51.5-2.02.0-1.8
Food consumed during 24 hour testing period5.06.07.42.5-2.52.5-2.42.42.3-2.32.3-2.32.7-2.72.5
Times rat made contact with spout0.00.00.1-0.10.1-0.20.10.1-0.10.1-0.20.20.2-0.20.1
Mean time between licks in bursts0.10.20.30.4-0.40.4-0.20.50.5-0.50.3-0.30.3-0.30.5
Mean num. licks in bursts2.22.64.51.4-1.41.3-1.41.81.5-1.51.4-1.42.1-2.11.9
Std. dev. time between licks in bursts0.00.10.2-0.20.2-0.10.1-0.1-0.30.3-0.40.40.1-0.1-0.1
Water consumed over 24 hours0.20.20.60.2-0.20.1-0.10.80.5-0.50.2-0.20.6-0.60.7
Indifference point 0 sec0.30.40.6-0.60.7-0.40.7-0.7-0.60.6-0.60.6-0.80.8-0.7
Indifference point AUC2.73.24.1-1.91.9-1.91.9-1.6-1.61.5-1.71.7-2.02.0-1.7
Indifference point function ln k0.81.11.61.0-1.01.2-1.10.90.9-0.81.0-1.01.3-1.30.9
Indifference point function log k0.81.11.61.0-1.01.2-1.10.90.9-0.81.0-1.01.3-1.30.9
Delay discounting total patch changes 0 sec0.60.91.1-1.01.0-0.70.9-1.1-1.01.0-0.90.9-0.90.9-1.1
Delay discounting total patch changes 12 sec0.81.11.8-1.01.0-1.21.2-0.8-0.70.7-1.01.0-1.31.3-0.9
Delay discounting total patch changes 18 sec2.53.34.4-1.91.9-1.61.7-1.9-2.12.1-1.91.9-1.61.6-1.9
Delay discounting total patch changes 24 sec0.30.40.6-0.60.6-0.70.6-0.6-0.70.7-0.60.6-0.40.4-0.6
Delay discounting total patch changes 6 sec1.92.93.5-1.81.8-1.61.8-1.5-1.51.4-1.71.7-1.91.9-1.6
Delay discounting time to switch 0 sec3.95.97.32.7-2.72.6-2.52.32.3-2.32.3-2.32.4-2.42.4
Delay discounting water rate 0 sec3.96.27.5-2.72.7-2.72.6-2.4-2.32.3-2.22.2-2.62.6-2.5
Delay discounting water rate 12 sec0.40.61.1-1.01.0-1.10.7-0.9-0.90.9-0.60.6-0.50.5-0.8
Delay discounting water rate 18 sec0.30.40.7-0.60.7-0.80.4-0.8-0.70.8-0.30.3-0.30.3-0.7
Delay discounting water rate 24 sec0.70.91.5-1.01.0-1.20.9-1.0-1.01.0-0.80.8-0.90.9-1.0
Delay discounting water rate 6 sec1.21.83.0-1.41.4-1.41.0-1.6-1.71.7-1.11.1-0.90.9-1.5
Locomotor activity1.52.43.7-1.71.7-1.61.6-1.4-1.11.1-1.31.3-1.91.9-1.6
Locomotor testing distance0.50.91.4-1.21.2-1.00.9-0.9-0.70.7-0.60.6-1.11.1-1.0
Locomotor testing rearing5.07.88.7-2.92.9-2.82.8-2.7-2.72.7-2.72.7-2.92.9-2.8
Light reinforcement 10.20.30.7-0.80.8-0.80.5-0.3-0.60.6-0.60.6-0.10.1-0.3
Light reinforcement 20.10.20.5-0.40.5-0.70.2-0.4-0.50.5-0.50.5-0.20.2-0.4
Reaction time number correct5.27.59.6-3.13.1-3.02.9-2.6-2.62.6-2.42.4-2.82.8-2.6
Reaction time mean minus median0.10.10.20.2-0.2-0.2-0.1-0.1-0.40.4-0.30.30.3-0.3-0.0
Reaction time mean minus median AUC0.60.71.5-0.60.6-1.00.6-0.9-1.21.2-1.01.0-0.40.4-0.8
Reaction time num false alarms5.06.98.2-2.92.9-2.72.4-2.6-2.82.8-2.72.7-2.32.3-2.6
Reaction time num false alarms AUC3.95.46.4-2.52.5-2.52.1-2.2-2.42.4-2.32.3-2.12.1-2.2
Reaction time trials correct on left5.27.59.6-3.13.1-3.02.9-2.6-2.62.6-2.42.4-2.82.8-2.6
Reaction time trials on left5.37.59.6-3.13.1-3.02.9-2.6-2.62.6-2.42.4-2.82.8-2.6
Reaction time mean0.70.91.81.1-1.10.8-1.01.00.5-0.50.5-0.51.3-1.31.1
Reaction time mean AUC0.50.71.50.9-1.00.6-0.80.90.5-0.50.5-0.51.2-1.20.9
Median of all reaction times1.21.62.51.4-1.41.1-1.21.41.0-1.00.9-0.91.6-1.61.5
Reaction time omissions0.20.30.7-0.50.5-0.80.5-0.2-0.60.5-0.70.7-0.20.2-0.2
Reaction time false alarm rate0.20.20.4-0.40.5-0.50.2-0.5-0.60.6-0.60.6-0.30.3-0.5
Reaction time premature initiation rate0.40.60.80.9-0.80.4-0.70.90.7-0.80.4-0.40.9-0.90.8
Reaction time premature initiations0.40.51.3-0.70.7-1.10.7-0.5-0.60.6-0.90.9-0.50.5-0.5
Std. dev. reaction times0.10.10.20.5-0.5-0.1-0.30.2-0.10.1-0.10.10.5-0.50.3
Reaction time trials completed5.37.59.6-3.13.1-3.02.9-2.6-2.62.6-2.42.4-2.82.8-2.6
Reaction time trials AUC6.49.211.8-3.43.4-3.33.2-2.9-2.92.9-2.72.7-3.03.0-2.9
Social response proportion1.92.13.4-1.41.4-1.91.4-1.3-1.61.6-1.61.6-1.01.0-1.3
Social responses1.01.21.6-1.11.1-1.11.0-1.1-1.31.3-1.21.2-0.90.9-1.1
Social time3.44.45.62.4-2.32.1-2.31.91.9-1.92.0-2.02.2-2.21.9
Conditioned locomotion0.40.51.40.5-0.60.1-0.11.11.1-1.20.4-0.40.2-0.20.8
Cocaine response after cond. corrected0.70.71.1-0.80.8-1.01.0-0.6-0.80.8-1.11.1-0.80.8-0.7
Cocaine response after cond. not corrected1.71.92.9-1.41.3-1.51.6-0.9-1.31.2-1.71.7-1.31.3-1.1
Cocaine response before conditioning1.31.62.3-1.41.3-1.21.5-0.8-1.00.9-1.51.5-1.51.5-1.0
Saline control response1.41.92.4-1.51.5-1.31.4-1.4-1.31.3-1.21.2-1.51.5-1.5
Condit. Reinf. active minus inactive responses0.10.10.3-0.40.4-0.50.4-0.1-0.30.3-0.50.5-0.30.3-0.2
Condit. Reinf. active-inactive response ratio0.60.61.3-0.90.9-1.21.0-0.3-0.50.5-0.90.9-0.70.7-0.4
Condit. Reinf. active responses0.10.10.30.4-0.40.2-0.20.50.4-0.50.3-0.30.3-0.30.5
Condit. Reinf. inactive responses0.81.01.41.2-1.11.2-1.10.90.9-0.91.0-1.00.9-0.91.0
Condit. Reinf. lever presses0.60.91.5-1.11.1-0.90.8-1.0-1.21.2-0.80.8-0.60.6-0.9
Condit. Reinf. lever reinforcers received0.10.20.40.4-0.50.2-0.30.60.5-0.60.3-0.30.3-0.30.6
Pavlov. Cond. lever latency0.00.00.0-0.00.00.2-0.00.10.1-0.10.0-0.00.1-0.10.0
Pavlov. Cond. magazine entry latency0.50.61.6-0.70.6-0.90.5-0.8-1.21.3-0.70.7-0.00.0-0.6
Pavlov. Cond. change in total contacts0.10.10.30.2-0.2-0.1-0.20.1-0.20.30.1-0.10.5-0.50.2
Pavlov. Cond. index score0.10.20.6-0.30.2-0.50.2-0.5-0.70.8-0.20.20.1-0.1-0.3
Pavlov. Cond. latency score0.10.10.3-0.10.1-0.30.0-0.3-0.50.6-0.10.10.3-0.3-0.1
Pavlov. Cond. lever contacts0.30.40.7-0.70.7-0.80.6-0.7-0.80.9-0.60.6-0.50.5-0.6
Pavlov. Cond. magazine entry number0.20.20.6-0.30.30.00.40.20.5-0.6-0.20.2-0.80.8-0.0
Pavlov. Cond. intertrial magazine entries0.10.10.50.2-0.20.4-0.00.50.6-0.70.1-0.1-0.10.10.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-0.50.5-0.70.4-0.6-0.90.9-0.40.4-0.00.0-0.4
Pavlov. Cond. response bias0.20.30.6-0.40.4-0.80.4-0.5-0.80.8-0.50.5-0.10.1-0.4
Conditioned reinforcement - actives0.90.91.3-0.90.9-1.21.1-0.8-0.90.9-0.80.8-1.01.0-0.9
Conditioned reinforcement - inactives0.60.61.5-0.60.5-1.20.9-0.6-0.70.7-0.90.9-0.90.9-0.6
Conditioned locomotion3.23.84.2-1.91.9-2.02.0-1.9-2.12.1-2.02.0-1.91.9-1.9
Intermittent access intake day 1-15 change0.50.51.4-0.90.9-1.20.5-0.7-0.80.8-0.50.5-0.50.5-0.7
Intermittent access intake escalation0.60.61.4-1.01.0-1.20.5-0.7-0.70.8-0.50.5-0.50.5-0.6
Intermittent access intake escalation 20.60.61.6-1.21.3-1.20.6-0.5-0.50.5-0.60.6-0.60.6-0.5
Intermitt. access day 1 inactive lever presses0.30.30.70.1-0.2-0.70.5-0.7-0.80.8-0.40.4-0.40.4-0.6
Intermitt. access day 15 inactive lever presses0.60.71.8-0.10.1-0.80.6-1.2-1.31.3-0.50.5-0.60.6-1.1
Intermitt. access escalation Index0.20.20.30.4-0.4-0.0-0.50.30.4-0.40.5-0.50.5-0.50.3
Intermittent access day 1 total infusions0.50.51.1-0.60.5-0.51.0-0.8-0.60.6-0.50.5-1.01.0-0.8
Intermittent access day 15 total infusions0.60.70.9-0.90.8-0.90.8-1.0-0.80.9-0.40.4-0.90.9-0.9
Intermittent access terminal intake (last 3 days)0.91.01.3-1.00.9-1.01.1-1.1-1.01.1-0.70.7-1.11.1-1.1
Intermittent access total infusions1.61.82.4-1.21.1-1.31.5-1.5-1.31.4-1.11.1-1.51.5-1.4
Intermittent access day 1 locomotion0.10.10.3-0.20.2-0.20.6-0.1-0.00.0-0.20.2-0.50.5-0.2
Intermittent access day 15 total locomotion0.40.40.7-0.90.8-0.80.7-0.7-0.50.6-0.20.2-0.70.7-0.6
Intermittent access total locomotion1.51.72.4-1.21.2-1.41.5-1.3-1.31.3-1.11.1-1.51.5-1.3
Intermittent access standard deviation0.60.60.8-0.80.8-0.90.8-0.8-0.80.9-0.60.6-0.70.7-0.7
Cocaine induced anxiety1.21.42.91.7-1.71.0-1.20.90.9-0.91.2-1.21.1-1.11.0
Post-drug Anxiety0.20.20.70.8-0.80.4-0.40.20.1-0.10.3-0.30.5-0.50.3
Baseline Anxiety0.60.70.9-1.01.0-0.60.8-0.8-0.90.9-0.80.8-0.70.7-0.8
Lifetime Intake1.11.21.9-1.00.9-1.01.3-1.2-1.11.1-0.80.8-1.41.4-1.2
Incentive Sensitization - Responses0.50.51.5-0.40.4-0.60.3-1.0-1.11.2-0.50.5-0.30.3-0.8
Incentive Sensitization - Breakpoint0.40.41.4-0.30.3-0.60.2-1.0-1.11.2-0.50.5-0.20.2-0.8
Progressive ratio test 1 active lever presses0.50.51.1-0.50.5-0.60.9-0.6-0.50.4-0.50.5-1.01.0-0.7
Progressive ratio test 1 breakpoint0.30.30.7-0.40.4-0.50.8-0.5-0.30.3-0.40.4-0.90.9-0.6
Progressive ratio test 1 inactive lever presses0.50.50.8-0.40.3-0.90.8-0.8-0.80.8-0.50.5-0.80.8-0.8
Progressive ratio test 2 active lever presses0.30.30.5-0.30.3-0.40.5-0.7-0.70.7-0.40.4-0.50.5-0.6
Progressive ratio test 2 breakpoint0.20.20.5-0.20.1-0.40.4-0.7-0.70.7-0.30.3-0.40.4-0.6
Progressive ratio test 2 inactive lever presses0.00.00.20.4-0.4-0.2-0.1-0.2-0.20.20.2-0.20.1-0.1-0.1
Total sessions with >9 infusions2.32.53.5-1.41.4-1.51.9-1.6-1.51.5-1.41.4-1.91.9-1.6
Short access day 1 total inactive lever presses1.31.51.9-1.01.0-1.41.1-1.4-1.41.4-1.01.0-1.21.2-1.4
Short access day 10 total inactive lever presses0.30.40.70.7-0.70.5-0.80.40.3-0.30.6-0.60.8-0.80.5
Short access day 1 total infusions0.50.61.0-1.01.0-0.41.0-0.6-0.50.4-0.50.5-1.01.0-0.7
Short access day 10 total infusions1.61.72.8-1.00.9-1.01.7-1.4-1.31.3-1.11.1-1.61.6-1.5
Short access total infusions0.20.20.5-0.30.2-0.00.7-0.4-0.20.2-0.20.2-0.70.7-0.4
Short access day 1 locomotion0.80.81.2-1.11.1-0.71.1-0.8-0.80.8-0.70.7-1.11.1-0.9
Short access day 10 total locomotion0.10.10.4-0.60.7-0.30.2-0.0-0.10.1-0.10.1-0.00.00.0
Short access total locomotion0.10.10.2-0.10.1-0.20.50.00.1-0.1-0.10.1-0.40.4-0.0
Compulsive drug intake0.10.10.40.5-0.6-0.40.2-0.1-0.30.2-0.40.4-0.10.1-0.2
One hour access (0.3 mA shock)0.00.00.1-0.00.1-0.1-0.2-0.3-0.30.30.3-0.30.1-0.1-0.1
One hour access (shock baseline)1.51.72.6-1.61.6-1.41.2-1.4-1.41.5-0.90.9-1.21.2-1.3
Number of responses in last shaping day3.23.35.2-2.22.3-1.61.8-1.8-1.71.7-1.51.5-1.81.8-1.8
Context. condit. distance diff. score0.20.20.4-0.60.6-0.50.4-0.5-0.60.7-0.40.4-0.30.3-0.5
Locomotion velocity, session 10.10.10.30.3-0.30.5-0.2-0.00.1-0.10.3-0.3-0.00.00.0
Locomotion distance, session 10.10.10.3-0.40.4-0.10.2-0.4-0.50.5-0.40.4-0.20.2-0.4
Locomotion velocity, session 20.81.02.0-0.90.9-0.91.0-0.8-0.70.7-1.01.0-1.41.4-0.9
Locomotion distance, session 20.30.40.8-0.60.6-0.60.7-0.5-0.60.6-0.90.9-0.60.6-0.6
Locomotion velocity, session 30.10.20.3-0.50.5-0.40.5-0.2-0.20.2-0.50.5-0.50.5-0.3
Locomotion distance, session 31.31.42.41.2-1.21.1-0.81.51.4-1.50.9-0.91.0-1.01.4
Stereotopy head waving bouts, day 30.50.61.3-0.80.8-0.81.0-0.4-0.30.3-0.70.7-1.11.1-0.5
Stereotopy head waving duration, day 30.80.91.2-1.11.1-1.01.0-0.9-0.90.9-0.90.9-1.11.1-0.9
Locomotion velocity, session 70.10.10.30.2-0.20.2-0.30.30.1-0.10.2-0.20.5-0.50.3
Locomotion distance, session 70.10.10.4-0.30.3-0.20.2-0.4-0.60.6-0.40.40.0-0.0-0.3
Stereotopy head waving bouts, day 70.50.60.9-0.80.8-0.90.9-0.6-0.60.6-0.70.7-0.90.9-0.6
Stereotopy head waving duration, day 70.50.60.9-0.90.8-0.80.8-0.7-0.60.6-0.60.6-1.01.0-0.8
Locomotion velocity, session 80.10.10.30.3-0.30.3-0.10.50.5-0.50.2-0.2-0.00.00.4
Locomotion distance, session 80.10.10.2-0.40.4-0.20.2-0.3-0.40.4-0.40.4-0.00.0-0.3
Degree of sensitization distance1.21.22.4-1.11.1-0.90.7-1.5-1.51.6-0.80.8-0.70.7-1.3
Degree of sensitization stereotypy0.90.91.3-1.00.9-1.21.0-0.8-0.80.8-0.90.9-1.11.1-0.9
Condit. Reinf. active minus inactive responses0.60.61.0-0.80.8-1.00.8-0.7-0.90.9-0.90.9-0.60.6-0.7
Condit. Reinf. active-inactive response ratio0.60.71.2-0.90.9-1.10.7-0.8-1.01.0-0.80.8-0.40.4-0.7
Condit. Reinf. active responses0.40.51.0-0.80.7-1.00.7-0.6-0.80.8-0.80.8-0.50.5-0.6
Condit. Reinf. inactive responses0.00.00.0-0.10.1-0.20.1-0.0-0.10.1-0.20.20.1-0.1-0.0
Incentive salience index mean0.20.30.6-0.50.5-0.80.6-0.3-0.40.4-0.60.6-0.50.5-0.4
Condit. Reinf. lever presses0.00.00.00.1-0.1-0.2-0.00.10.1-0.2-0.00.0-0.00.00.1
Time in familiar zone, hab. session 10.20.20.2-0.40.4-0.40.4-0.4-0.50.5-0.40.4-0.40.4-0.4
Time in novel zone, hab. session 10.60.60.7-0.80.8-0.80.8-0.7-0.80.8-0.70.7-0.80.8-0.7
Total zone transitions, hab. session 10.30.40.6-0.70.7-0.60.6-0.7-0.80.8-0.70.7-0.40.4-0.7
Total locomotion distance, hab. session 10.40.60.80.8-0.80.9-0.80.70.7-0.70.7-0.70.8-0.80.7
Locomotion velocity, hab. session 11.21.72.01.4-1.41.4-1.41.21.2-1.21.3-1.31.4-1.41.2
Time in familiar zone, hab. session 20.20.20.7-0.40.4-0.40.2-0.8-0.60.6-0.00.0-0.50.5-0.7
Time in novel zone, hab. session 20.00.00.0-0.00.0-0.00.10.1-0.10.1-0.20.20.2-0.20.1
Total zone transitions, hab. session 20.40.50.9-0.60.6-0.70.8-0.5-0.50.4-0.70.7-0.90.9-0.5
Total locomotion distance, hab. session 20.71.01.41.2-1.21.0-0.91.01.0-1.00.9-0.90.8-0.81.0
Locomotion velocity, hab. session 20.50.71.01.0-1.00.8-0.70.90.9-0.90.7-0.70.7-0.70.9
Novel to familiar place preference ratio1.61.72.3-1.51.5-1.41.2-1.2-1.51.5-1.51.5-0.70.7-1.2
Novelty place preference1.51.52.1-1.41.4-1.41.1-1.1-1.41.4-1.41.4-0.70.7-1.1
Time in novel zone, NPP test1.81.92.5-1.51.5-1.61.3-1.2-1.61.6-1.51.5-0.80.8-1.2
Total zone transitions, NPP test0.10.20.4-0.30.3-0.00.3-0.5-0.40.4-0.40.4-0.60.6-0.5
Total locomotion distance, NPP test0.20.20.5-0.30.4-0.10.3-0.7-0.70.7-0.50.5-0.40.4-0.6
Locomotion velocity, NPP test0.10.20.3-0.20.3-0.00.2-0.6-0.50.5-0.40.4-0.40.4-0.6
Pavlov. Cond. lever latency0.30.30.50.5-0.50.5-0.60.50.5-0.40.7-0.70.7-0.70.6
Pavlov. Cond. magazine entry latency0.20.20.5-0.40.5-0.30.3-0.7-0.70.7-0.40.4-0.30.3-0.6
Pavlov. Cond. change in total contacts0.60.60.70.9-0.90.6-0.70.90.7-0.80.6-0.60.8-0.80.9
Pavlov. Cond. index score0.20.20.3-0.50.5-0.50.5-0.4-0.50.4-0.50.5-0.50.5-0.5
Pavlov. Cond. latency score0.00.00.1-0.10.1-0.10.2-0.1-0.10.1-0.20.2-0.20.2-0.2
Pavlov. Cond. lever contacts0.40.50.7-0.70.7-0.60.7-0.6-0.70.6-0.80.8-0.80.8-0.7
Pavlov. Cond. magazine entry number0.00.00.10.1-0.10.1-0.10.20.2-0.30.1-0.10.0-0.00.1
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.30.2-0.60.50.0-0.20.1-0.50.5-0.30.3-0.0
Pavlov. Cond. lever-magazine prob. diff.0.30.30.4-0.60.6-0.60.7-0.4-0.50.4-0.70.7-0.70.7-0.5
Pavlov. Cond. response bias1.41.72.0-1.41.4-1.31.2-1.3-1.41.4-1.31.3-1.11.1-1.3
Bone: apparent density0.00.00.2-0.10.10.0-0.2-0.0-0.20.2-0.10.10.4-0.40.0
Bone surface0.20.30.6-0.60.6-0.40.4-0.7-0.80.8-0.60.6-0.30.3-0.6
Bone volume0.10.20.4-0.50.5-0.30.2-0.6-0.60.6-0.50.5-0.10.1-0.5
Bone: connectivity density0.00.10.30.1-0.10.2-0.30.0-0.10.1-0.00.00.5-0.50.1
Bone: cortical apparent density0.00.00.00.0-0.00.1-0.20.10.0-0.00.1-0.10.2-0.20.1
Bone: cortical area1.11.61.9-1.31.4-1.21.1-1.3-1.21.2-1.31.3-1.41.4-1.4
Bone: cortical porosity0.91.02.60.9-0.90.6-0.41.41.5-1.60.8-0.80.3-0.31.2
Bone: cortical porosity0.40.51.50.5-0.50.2-0.11.01.1-1.20.4-0.4-0.00.00.8
Bone: cortical thickness0.30.50.8-0.70.7-0.90.6-0.6-0.60.5-0.70.7-0.70.7-0.7
Bone: cortical thickness1.21.42.1-1.21.2-1.51.2-1.0-1.01.0-1.21.2-1.31.3-1.1
Bone: cortical tissue density0.00.00.10.1-0.10.2-0.30.10.1-0.10.2-0.20.3-0.30.2
Bone: elastic displacement1.61.82.31.5-1.50.9-1.21.41.4-1.41.2-1.21.4-1.41.4
Bone: elastic work0.00.00.2-0.0-0.0-0.40.10.30.3-0.3-0.00.0-0.00.00.2
Bone: endosteal estimation0.00.00.10.1-0.10.3-0.20.10.1-0.10.1-0.10.3-0.30.2
Bone: endosteal perimeter0.00.00.1-0.10.10.4-0.1-0.3-0.10.20.1-0.1-0.10.1-0.2
Bone: final force0.30.50.7-0.80.8-0.70.7-0.6-0.60.6-0.70.7-0.70.7-0.7
Bone: final moment0.40.70.9-1.01.0-0.90.8-0.7-0.80.7-0.90.9-0.90.9-0.8
Bone: marrow area0.00.00.10.1-0.10.2-0.10.10.1-0.10.1-0.10.2-0.20.1
Bone: maximum diameter1.93.54.0-1.81.8-1.61.7-1.9-1.91.9-1.91.9-2.02.0-2.0
Bone: maximum force0.20.30.5-0.70.7-0.50.5-0.6-0.50.5-0.50.5-0.50.5-0.6
Bone: maximum moment0.30.40.6-0.80.8-0.60.6-0.6-0.60.6-0.60.6-0.70.7-0.7
Bone: minimum diameter0.20.40.6-0.80.8-0.50.6-0.7-0.60.7-0.50.5-0.50.5-0.6
Bone: periosteal estimation0.20.30.4-0.60.6-0.40.5-0.6-0.60.6-0.60.6-0.60.6-0.6
Bone: periosteal perimeter0.20.20.4-0.50.5-0.10.3-0.6-0.50.5-0.40.4-0.50.5-0.6
Bone: post-yield work0.30.40.70.4-0.40.8-0.80.20.3-0.30.7-0.70.8-0.80.4
Bone: stiffness0.91.41.9-1.31.3-0.81.0-1.4-1.31.3-1.11.1-1.11.1-1.3
Bone: tissue strength0.40.30.50.5-0.60.3-0.50.70.6-0.60.5-0.50.7-0.70.7
Bone: trabecular number0.10.20.60.4-0.30.4-0.50.40.3-0.30.3-0.30.8-0.80.4
Bone: trabecular spacing0.20.20.4-0.30.3-0.30.5-0.4-0.40.4-0.50.5-0.60.6-0.4
Bone: trabecular thickness1.21.42.2-1.41.4-1.51.2-1.1-1.21.2-1.11.1-1.01.0-1.1
Bone: trabecular tissue density0.81.11.7-1.11.1-1.31.0-1.0-1.01.0-0.90.9-1.11.1-1.0
Breakpoint value in progressive ratio session5.46.07.12.7-2.62.1-2.52.22.3-2.22.6-2.62.5-2.52.3
Distance traveled before self-admin0.20.20.4-0.50.5-0.40.5-0.4-0.40.4-0.60.6-0.50.5-0.5
Distance traveled after self-admin0.91.01.81.0-1.01.3-0.91.01.1-1.21.0-1.00.8-0.80.9
Delta time in closed arm before/after self-admin0.00.00.2-0.10.1-0.40.1-0.2-0.30.3-0.10.1-0.10.1-0.2
Delta time in open arm before/after self-admin0.30.30.70.5-0.50.9-0.40.70.7-0.70.3-0.30.4-0.40.6
Diff in mean of infusions in LGA sessions3.94.45.32.2-2.21.8-2.21.82.0-2.02.3-2.32.1-2.11.9
Extinction: sum of active levers before priming2.52.53.51.7-1.71.1-1.41.71.8-1.91.5-1.51.4-1.41.7
Active lever presses in extinction session 60.30.21.1-0.30.3-1.10.1-0.4-0.60.7-0.50.5-0.10.1-0.3
Delta distance traveled before/after self-admin3.63.84.62.1-2.12.1-2.01.71.9-1.92.0-2.01.9-1.91.8
Delta ambulatory time before/after self-admin1.41.51.71.3-1.31.3-1.11.11.3-1.31.3-1.31.1-1.11.2
Time in closed arm before self-admin1.72.02.3-1.51.5-1.51.3-1.4-1.41.4-1.31.3-1.41.4-1.4
Time in closed arm after self-admin0.10.10.6-0.20.2-0.80.0-0.4-0.30.30.1-0.1-0.10.1-0.3
Time in open arm before self-admin1.01.01.31.1-1.10.9-0.91.11.1-1.10.9-0.91.0-1.01.1
Time in open arm after self-admin1.51.62.91.2-1.31.4-0.91.61.6-1.70.8-0.81.0-1.01.5
Sum of active levers in priming session hrs 5-61.71.72.41.4-1.40.9-1.11.41.5-1.51.4-1.41.1-1.11.3
Time to tail flick, vehicle, before self-admin2.72.83.7-1.81.8-1.71.9-1.2-1.31.3-1.81.8-1.91.9-1.4
Time to tail flick, vehicle, after self-admin0.70.81.9-0.80.8-0.60.5-1.2-1.31.4-0.70.7-0.50.5-1.0
Time to tail flick, test, before self-admin1.01.02.40.9-1.00.8-0.41.51.4-1.60.4-0.40.6-0.61.3
Time to tail flick, test, after self-admin0.10.10.4-0.30.20.60.3-0.1-0.0-0.0-0.10.1-0.30.3-0.1
Delta time to tail flick, vehicle, before/after SA0.10.10.20.1-0.10.1-0.2-0.3-0.40.50.0-0.00.2-0.2-0.2
Delta time to tail flick, test, before/after SA2.42.22.8-1.61.7-0.81.3-1.7-1.61.7-1.31.3-1.41.4-1.6
Ambulatory time before self-admin0.00.00.0-0.10.1-0.10.1-0.1-0.00.0-0.10.1-0.10.1-0.1
Ambulatory time after self-admin1.21.31.61.2-1.21.3-1.11.11.2-1.21.2-1.21.1-1.11.1
Total heroin consumption0.40.50.70.8-0.80.2-0.80.70.6-0.60.7-0.70.8-0.80.7
Area under the delay curve2.22.34.01.6-1.61.7-1.61.11.4-1.32.0-2.01.4-1.41.2
Delay disc. indifference point, 0s delay1.51.62.11.3-1.31.1-1.11.31.5-1.41.4-1.41.1-1.11.3
Delay disc. indifference point, 16s delay1.11.12.01.1-1.11.0-1.20.50.8-0.71.4-1.41.1-1.10.7
Delay disc. indifference point, 2s delay3.43.85.82.1-2.12.1-2.21.31.6-1.42.4-2.41.8-1.81.6
Delay disc. indifference point, 24s delay0.40.41.1-0.70.7-0.40.4-0.9-1.01.1-0.30.3-0.20.2-0.7
Delay disc. indifference point, 4s delay0.00.00.1-0.10.00.10.10.00.1-0.10.2-0.2-0.10.10.1
Delay disc. indifference point, 8s delay2.32.33.81.6-1.51.8-1.51.11.4-1.41.9-1.91.3-1.31.2
Delay discount exponential model param1.61.73.0-1.31.3-1.51.3-0.8-1.11.0-1.71.7-1.21.2-1.0
Delay discount hyperbolic model param1.31.42.6-1.21.2-1.41.2-0.7-1.00.9-1.61.6-1.01.0-0.9
Fecal boli incidents, locomotor time 10.00.00.10.1-0.1-0.2-0.0-0.1-0.20.2-0.20.2-0.00.0-0.1
Change in fecal boli incidents, locomotor task0.90.91.00.9-0.91.0-0.90.90.9-0.90.9-0.90.9-0.90.9
Time >=10cm from walls, locomotor time 10.10.10.3-0.20.2-0.5-0.0-0.2-0.40.5-0.10.10.3-0.3-0.1
Bouts of movement, locomotor time 11.92.12.91.6-1.61.6-1.51.21.1-1.11.4-1.41.7-1.71.3
Total resting periods, locomotor time 12.42.63.41.8-1.81.8-1.71.31.3-1.21.6-1.61.8-1.81.5
Rest time, locomotor task time 10.00.00.10.3-0.30.2-0.2-0.0-0.00.10.1-0.10.3-0.30.0
Distance moved, locomotor task time 10.10.10.5-0.40.4-0.70.40.0-0.0-0.0-0.40.4-0.50.5-0.1
Vertical activity count, locomotor time 10.20.20.60.3-0.3-0.1-0.30.80.7-0.70.2-0.20.3-0.30.7
Time >=10cm from walls, locomotor time 20.20.20.40.4-0.4-0.3-0.30.60.4-0.50.2-0.20.3-0.30.6
Bouts of movement, locomotor time 24.24.56.42.3-2.31.7-2.41.81.7-1.62.2-2.22.5-2.51.9
Total resting periods, locomotor time 23.84.05.72.2-2.21.6-2.31.71.6-1.62.0-2.02.4-2.41.8
Rest time, locomotor task time 20.10.10.50.3-0.30.7-0.10.30.3-0.3-0.00.00.3-0.30.2
Distance moved, locomotor task time 20.50.61.8-0.90.9-1.30.8-0.4-0.50.4-0.70.7-0.90.9-0.4
Vertical activity count, locomotor time 20.20.20.30.3-0.3-0.4-0.50.50.5-0.40.5-0.50.4-0.40.5
Weight adjusted by age0.00.00.10.2-0.20.3-0.20.10.1-0.10.2-0.20.1-0.10.1
Seeking ratio, delayed vs. immediate footshock2.12.43.11.5-1.51.4-1.31.61.8-1.81.7-1.71.4-1.41.5
Locomotion in novel chamber0.60.70.90.9-0.90.8-0.70.80.9-0.90.9-0.90.7-0.70.7
Locomotion in novel chamber post-restriction1.61.92.51.6-1.61.0-1.31.51.5-1.51.2-1.21.2-1.21.4
Progressive ratio0.60.71.71.0-1.01.3-0.90.50.6-0.50.9-0.90.8-0.80.6
Food seeking constrained by brief footshock6.47.810.22.7-2.72.6-2.43.13.2-3.22.6-2.62.7-2.73.0
Seeking ratio, punishment vs. effort1.21.42.60.9-1.00.6-0.81.51.6-1.61.1-1.11.1-1.11.4
Run reversals in cocaine runway, females0.20.20.50.6-0.60.2-0.70.00.00.10.5-0.50.6-0.60.2
Run reversals in cocaine runway, males0.70.71.1-0.90.8-0.51.0-0.6-0.70.7-1.11.1-0.90.9-0.7
Latency to leave start box in cocaine runway0.20.20.7-0.60.6-0.40.2-0.7-0.80.8-0.20.2-0.10.1-0.6
Latency to leave start box in cocaine runway, F0.50.60.8-0.90.9-0.80.7-0.8-0.70.8-0.50.5-0.70.7-0.8
Latency to leave start box in cocaine runway, M0.40.41.2-0.60.6-0.40.2-0.8-1.01.1-0.40.40.1-0.1-0.6
Cd content in liver0.00.00.20.0-0.0-0.4-0.0-0.2-0.30.3-0.10.10.1-0.1-0.2
Co content in liver2.22.53.61.9-1.91.3-1.51.71.5-1.61.4-1.41.6-1.61.7
Cu content in liver0.10.10.1-0.20.2-0.20.2-0.4-0.30.3-0.30.3-0.20.2-0.3
Fe content in liver1.01.21.8-1.11.1-0.80.9-1.4-1.11.1-0.80.8-1.31.3-1.3
K content in liver0.10.10.20.0-0.1-0.10.30.20.4-0.4-0.10.1-0.50.50.0
Mg content in liver0.10.10.20.0-0.1-0.10.30.40.4-0.5-0.00.0-0.50.50.2
Mn content in liver0.70.81.7-0.70.7-1.21.30.2-0.1-0.1-1.11.1-1.11.1-0.1
Na content in liver0.20.20.40.5-0.50.6-0.30.60.6-0.60.4-0.40.2-0.20.5
Rb content in liver0.10.10.4-0.30.3-0.10.1-0.5-0.60.7-0.40.40.1-0.1-0.4
Se content in liver0.70.92.1-0.90.8-1.11.2-0.4-0.20.2-0.90.9-1.51.5-0.6
Sr content in liver0.10.10.3-0.20.2-0.20.30.00.1-0.2-0.10.1-0.50.5-0.1
Zn content in liver0.20.20.4-0.30.2-0.30.3-0.5-0.60.6-0.50.5-0.20.2-0.5