Hub : Genes

Rusc2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000072869 0.04 0.04 5.4e-04 0.02 0.02 0.02 0.01 3.9e-03 2.0e-03 1.5e-03 7.5e-03
2 Adipose alternative TSS ENSRNOT00000102739 0.02 0.02 9.1e-03 0.02 0.01 0.01 0.01 2.8e-03 7.1e-02 5.0e-02 5.2e-02
3 Adipose isoform ratio ENSRNOT00000072869 0.07 0.06 1.2e-03 0.03 0.01 0.02 0.02 8.5e-04 7.3e-03 3.8e-03 3.8e-03
4 Adipose isoform ratio ENSRNOT00000100695 0.03 0.03 1.2e-03 0.02 0.02 0.02 0.01 4.8e-03 2.4e-03 4.8e-03 8.6e-03
5 Adipose mRNA stability ENSRNOG00000045843 0.05 0.04 1.3e-03 0.03 0.02 0.02 0.03 1.8e-04 2.1e-03 9.5e-04 3.9e-04
6 Brain gene expression ENSRNOG00000045843 0.07 0.04 5.6e-07 0.06 0.07 0.07 0.07 2.5e-06 4.8e-07 3.5e-07 5.3e-07
7 Brain isoform ratio ENSRNOT00000072869 0.26 0.12 7.4e-07 0.06 0.07 0.07 0.05 2.4e-06 5.8e-07 2.8e-07 8.9e-06
8 Brain isoform ratio ENSRNOT00000100695 0.07 0.05 9.0e-04 0.04 0.03 0.01 0.03 2.5e-04 1.3e-03 2.5e-02 9.8e-04
9 Brain isoform ratio ENSRNOT00000102739 0.2 0.12 1.9e-03 0.02 0.03 0.03 0.01 4.6e-03 1.1e-03 3.5e-04 1.5e-02
10 Liver alternative TSS ENSRNOT00000072869 0.04 0.03 6.3e-03 0 0 0.01 0.01 1.1e-01 8.5e-02 2.0e-02 6.8e-02
11 Liver intron excision ratio chr5:57672695:57672887 0.06 0.04 1.7e-04 0.03 0.04 0.03 0.03 3.4e-04 7.1e-05 3.4e-04 3.5e-04
12 Liver intron excision ratio chr5:57672695:57673342 0.09 0.05 1.4e-06 0.05 0.06 0.05 0.05 2.8e-06 8.1e-07 1.3e-06 2.1e-06
13 NAcc gene expression ENSRNOG00000045843 0.05 0.04 2.1e-04 0.05 0.04 0.04 0.04 1.8e-04 2.6e-04 3.5e-04 2.5e-04
14 NAcc mRNA stability ENSRNOG00000045843 0.04 0.03 5.2e-03 0.01 0.01 -0 0.01 5.6e-02 4.8e-02 4.2e-01 7.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail1.44.611.4-3.13.4-0.92.9-0.83.0-0.10.91.2-2.1-1.61.2-3.0-2.3
BMI without tail2.55.214.0-2.33.10.72.10.73.70.5-0.71.4-3.5-0.3-0.2-3.3-3.6
Body weight1.56.416.7-2.83.70.52.70.54.10.8-0.51.1-3.5-0.60.0-3.8-3.9
Epididymis fat weight0.20.41.4-0.10.30.50.20.51.10.1-0.50.4-0.50.3-0.4-1.0-1.2
Glucose0.50.82.1-0.81.30.40.70.41.40.4-0.40.3-1.2-0.0-0.2-1.3-1.4
Heart weight0.40.51.4-0.30.80.70.20.70.80.5-0.70.1-1.00.4-0.5-1.0-1.2
Left kidney weight0.41.32.9-0.00.81.3-0.11.41.01.4-1.3-0.7-1.51.0-1.2-1.0-1.7
Right kidney weight0.20.51.00.6-0.11.0-0.71.00.10.6-1.0-0.3-0.70.9-0.9-0.1-0.5
Tail length1.13.29.3-1.11.81.21.11.13.10.2-1.21.6-2.70.4-0.7-2.6-3.1
Length with tail0.41.65.0-0.00.71.50.11.41.80.9-1.40.3-1.60.9-1.2-1.5-2.2
Length without tail0.20.51.20.9-0.90.3-0.90.4-0.90.7-0.3-1.10.70.6-0.51.00.6
Liver weight, left0.30.42.30.2-0.40.10.10.10.8-1.1-0.11.50.40.00.0-0.8-0.6
Liver weight, right0.20.31.21.0-1.10.4-0.80.4-0.3-0.2-0.40.20.40.6-0.50.40.1
Parametrial fat weight0.10.30.80.2-0.10.6-0.20.70.40.2-0.60.2-0.90.6-0.6-0.3-0.8
Retroperitoneal fat weight0.10.30.6-0.0-0.3-0.70.0-0.6-0.5-0.70.70.40.7-0.40.50.10.8
Intraocular pressure1.31.85.3-0.71.51.10.61.11.81.3-1.1-0.3-2.30.6-0.9-1.2-2.2
Extensor digitorum longus weight2.08.021.2-3.03.90.62.80.64.60.9-0.61.4-4.1-0.5-0.1-4.3-4.4
Soleus weight1.54.48.12.5-1.82.8-2.52.7-0.71.7-2.7-1.2-1.12.8-2.81.1-1.0
Tibialis anterior weight2.89.828.1-2.53.91.62.31.65.01.4-1.61.3-5.00.4-1.1-4.3-5.3
Tibia length0.71.83.41.7-1.11.8-1.71.8-0.30.6-1.8-0.3-0.81.9-1.80.9-0.6
Number of licking bursts2.22.66.3-1.92.2-0.52.0-0.52.5-0.50.51.6-1.5-1.00.7-2.4-2.0
Food consumed during 24 hour testing period0.30.41.3-0.10.30.70.10.70.90.1-0.70.5-1.00.4-0.5-0.8-1.1
Times rat made contact with spout0.50.61.2-1.11.1-0.81.0-0.80.5-0.40.80.5-0.3-0.90.7-0.7-0.3
Mean time between licks in bursts0.50.72.91.0-1.7-0.3-0.7-0.3-0.8-1.20.30.91.10.00.20.71.0
Mean num. licks in bursts0.91.03.30.9-1.2-0.2-1.0-0.2-1.8-0.00.2-0.91.30.2-0.01.61.6
Std. dev. time between licks in bursts0.20.30.80.5-0.9-0.2-0.4-0.2-0.7-0.50.20.20.8-0.00.20.60.8
Water consumed over 24 hours0.40.51.6-1.01.3-0.20.9-0.20.90.10.20.3-0.9-0.40.2-0.9-0.9
Indifference point 0 sec3.15.113.41.00.32.7-1.22.70.43.7-2.7-3.1-2.42.4-2.7-0.0-2.0
Indifference point AUC3.64.312.0-2.12.90.72.00.73.50.6-0.71.2-2.7-0.3-0.2-3.2-3.2
Indifference point function ln k1.21.74.91.5-2.0-0.1-1.4-0.2-2.20.00.1-1.11.20.5-0.22.11.8
Indifference point function log k1.21.74.91.5-2.0-0.1-1.4-0.2-2.20.00.1-1.11.20.5-0.22.11.8
Delay discounting total patch changes 0 sec2.94.712.20.50.72.6-0.82.60.83.5-2.6-2.9-2.62.1-2.5-0.4-2.3
Delay discounting total patch changes 12 sec1.21.64.2-1.52.10.31.40.31.91.1-0.3-0.3-1.6-0.3-0.1-1.8-1.9
Delay discounting total patch changes 18 sec0.50.61.7-0.30.50.80.30.81.00.8-0.8-0.3-1.00.4-0.6-1.0-1.3
Delay discounting total patch changes 24 sec1.72.15.4-1.01.91.10.71.12.01.7-1.1-0.6-2.20.5-0.9-1.6-2.3
Delay discounting total patch changes 6 sec2.53.88.6-0.82.02.00.42.02.12.6-2.0-1.4-2.91.2-1.6-1.7-2.9
Delay discounting time to switch 0 sec1.82.77.51.1-2.1-1.3-0.8-1.2-2.3-1.51.30.42.7-0.61.01.82.7
Delay discounting water rate 0 sec1.82.97.4-0.82.11.50.41.51.72.4-1.5-1.6-2.71.0-1.4-1.1-2.5
Delay discounting water rate 12 sec0.30.40.70.4-0.20.7-0.50.8-0.10.8-0.7-0.8-0.60.8-0.80.3-0.5
Delay discounting water rate 18 sec0.40.51.9-1.11.4-0.51.0-0.50.70.40.5-0.2-0.6-0.60.4-0.6-0.5
Delay discounting water rate 24 sec0.71.02.0-1.31.0-1.41.1-1.40.1-0.71.40.30.1-1.31.2-0.30.5
Delay discounting water rate 6 sec0.30.41.6-0.40.80.30.40.20.90.3-0.30.1-1.30.2-0.3-0.5-1.0
Locomotor activity0.00.00.1-0.10.00.00.00.10.1-0.1-0.00.2-0.20.0-0.0-0.3-0.1
Locomotor testing distance0.50.81.51.1-0.81.2-1.11.2-0.20.8-1.2-0.6-0.51.2-1.20.3-0.4
Locomotor testing rearing0.40.61.60.10.10.8-0.00.71.00.3-0.80.4-1.30.6-0.7-0.9-1.2
Light reinforcement 12.85.110.31.7-0.73.1-1.83.20.82.1-3.1-1.2-2.52.8-3.0-0.1-2.3
Light reinforcement 24.76.312.52.4-1.23.4-2.43.50.22.6-3.4-1.9-1.73.3-3.30.7-1.9
Reaction time number correct0.30.40.80.10.40.8-0.30.80.20.9-0.8-0.7-0.80.6-0.7-0.1-0.7
Reaction time mean minus median3.54.67.7-2.11.0-2.62.3-2.51.1-2.62.62.81.0-2.62.6-1.70.6
Reaction time mean minus median AUC2.53.25.8-2.01.2-1.82.1-1.91.5-1.91.82.40.3-2.12.0-1.9-0.1
Reaction time num false alarms0.30.40.7-0.80.7-0.80.7-0.80.4-0.60.80.70.2-0.80.8-0.60.2
Reaction time num false alarms AUC0.30.41.2-0.81.1-0.10.7-0.20.80.10.10.3-0.6-0.40.3-1.0-0.5
Reaction time trials correct on left0.30.40.80.10.40.8-0.30.80.20.9-0.8-0.7-0.80.6-0.7-0.1-0.7
Reaction time trials on left0.20.30.70.10.30.7-0.30.80.10.8-0.7-0.7-0.70.6-0.7-0.1-0.6
Reaction time mean2.53.57.4-0.3-1.0-2.30.6-2.4-0.9-2.72.31.92.3-1.92.10.62.2
Reaction time mean AUC2.73.77.4-0.3-1.0-2.40.6-2.5-1.1-2.72.41.92.4-1.92.20.72.4
Median of all reaction times2.12.86.70.7-1.8-1.6-0.4-1.7-1.8-2.11.61.02.3-1.01.41.72.6
Reaction time omissions0.81.02.80.8-1.5-0.7-0.7-0.7-1.5-0.80.70.11.6-0.20.51.11.7
Reaction time false alarm rate0.20.30.6-0.50.4-0.70.5-0.80.1-0.50.70.50.3-0.70.7-0.40.4
Reaction time premature initiation rate1.21.64.20.3-1.0-1.3-0.2-1.2-1.8-0.61.3-0.42.0-0.80.91.52.1
Reaction time premature initiations0.60.82.30.3-0.7-0.8-0.3-0.7-1.5-0.10.8-0.71.3-0.40.51.31.5
Std. dev. reaction times2.94.07.9-1.40.1-2.61.6-2.60.2-2.82.62.61.6-2.42.5-0.71.4
Reaction time trials completed0.20.30.70.10.30.7-0.30.80.10.8-0.7-0.7-0.70.6-0.7-0.1-0.6
Reaction time trials AUC0.20.30.60.10.30.7-0.30.70.10.8-0.7-0.7-0.60.6-0.7-0.1-0.5
Social response proportion1.71.94.30.8-1.8-1.2-0.6-1.2-1.5-1.91.21.02.0-0.60.91.22.1
Social responses0.30.41.1-0.60.5-0.00.6-0.01.0-0.50.01.0-0.6-0.30.2-1.0-0.7
Social time0.40.62.21.0-1.50.1-0.80.1-0.5-1.2-0.11.30.60.3-0.10.30.5
Conditioned locomotion1.01.22.50.7-0.11.3-0.91.1-0.31.6-1.3-1.6-1.11.3-1.30.6-0.5
Cocaine response after cond. corrected2.83.15.22.2-1.71.8-2.31.9-1.71.5-1.8-2.00.12.0-1.92.00.5
Cocaine response after cond. not corrected3.13.56.12.5-2.02.1-2.42.1-1.61.4-2.1-1.7-0.02.2-2.11.80.3
Cocaine response before conditioning0.30.41.4-0.40.3-0.20.7-0.30.9-0.70.21.2-0.6-0.40.3-1.1-0.8
Saline control response1.01.43.00.60.11.6-0.51.70.71.1-1.6-0.5-1.41.3-1.4-0.4-1.6
Condit. Reinf. active minus inactive responses0.40.51.1-0.91.0-0.20.9-0.21.1-0.10.20.6-0.6-0.50.3-1.0-0.8
Condit. Reinf. active-inactive response ratio0.30.30.7-0.80.8-0.50.7-0.30.5-0.20.50.40.2-0.60.6-0.5-0.1
Condit. Reinf. active responses1.01.44.0-1.31.60.11.30.02.0-0.1-0.11.0-1.5-0.50.2-1.9-1.7
Condit. Reinf. inactive responses1.62.04.9-1.61.6-0.51.7-0.72.1-0.70.51.7-1.4-1.00.7-2.2-1.5
Condit. Reinf. lever presses1.92.65.0-2.11.8-1.12.1-1.22.0-1.21.12.0-0.8-1.61.4-2.2-1.1
Condit. Reinf. lever reinforcers received1.21.74.7-1.41.70.11.4-0.02.2-0.1-0.11.2-1.5-0.50.3-2.1-1.8
Pavlov. Cond. lever latency2.12.95.52.1-1.81.2-2.21.4-2.21.3-1.2-2.20.91.7-1.52.41.2
Pavlov. Cond. magazine entry latency0.50.51.30.5-1.0-0.6-0.3-0.5-0.7-1.10.60.71.1-0.30.50.41.0
Pavlov. Cond. change in total contacts2.13.06.2-1.70.9-1.91.9-2.01.2-2.21.92.50.4-2.02.0-1.40.1
Pavlov. Cond. index score1.01.32.8-0.90.3-1.31.2-1.40.6-1.61.31.70.5-1.41.4-0.80.3
Pavlov. Cond. latency score1.31.62.9-1.30.7-1.51.4-1.50.7-1.61.51.70.5-1.51.5-1.00.2
Pavlov. Cond. lever contacts1.01.43.0-1.41.2-0.81.5-0.91.6-0.90.81.6-0.7-1.11.0-1.7-0.9
Pavlov. Cond. magazine entry number1.31.63.30.9-0.21.6-1.11.6-0.21.8-1.6-1.6-1.11.5-1.60.6-0.7
Pavlov. Cond. intertrial magazine entries0.30.41.0-0.51.00.50.40.40.80.6-0.5-0.2-0.90.1-0.3-0.7-0.9
Pavlov. Cond. lever-magazine prob. diff.1.11.43.1-1.00.3-1.41.2-1.40.6-1.71.41.80.6-1.41.5-0.80.3
Pavlov. Cond. response bias0.81.12.4-1.00.6-1.01.2-1.11.0-1.21.01.5-0.2-1.11.1-1.2-0.2
Conditioned reinforcement - actives0.30.31.2-0.81.1-0.20.7-0.20.40.30.2-0.2-0.6-0.40.3-0.5-0.3
Conditioned reinforcement - inactives0.10.20.80.10.10.3-0.20.3-0.40.7-0.3-0.9-0.30.2-0.30.40.1
Conditioned locomotion0.50.62.5-0.91.60.20.60.20.51.0-0.3-0.8-1.1-0.1-0.1-0.7-0.7
Intermittent access intake day 1-15 change1.41.42.3-1.41.0-1.31.5-1.30.8-1.31.31.5-0.2-1.51.4-1.0-0.1
Intermittent access intake escalation1.41.32.4-1.51.3-1.11.6-1.11.1-1.01.11.4-0.6-1.31.2-1.1-0.5
Intermittent access intake escalation 22.42.44.0-1.91.6-1.62.0-1.61.2-1.41.61.7-0.5-1.91.7-1.2-0.2
Intermitt. access day 1 inactive lever presses0.40.41.3-0.71.10.20.60.20.80.6-0.2-0.2-1.0-0.1-0.1-0.7-1.0
Intermitt. access day 15 inactive lever presses0.40.51.40.3-0.00.7-0.40.7-0.11.2-0.7-1.1-1.10.7-0.80.1-0.5
Intermitt. access escalation Index0.70.62.00.20.21.0-0.11.01.00.6-1.0-0.1-0.50.8-1.0-0.5-1.4
Intermittent access day 1 total infusions1.41.65.40.70.01.3-1.11.3-0.82.1-1.3-2.3-0.81.3-1.30.7-0.2
Intermittent access day 15 total infusions0.50.52.0-0.91.40.10.70.10.60.8-0.1-0.5-1.3-0.20.0-0.7-0.8
Intermittent access terminal intake (last 3 days)0.70.72.7-1.01.60.30.70.30.71.1-0.3-0.7-1.5-0.1-0.1-0.7-1.0
Intermittent access total infusions1.01.13.1-1.01.70.60.60.60.71.5-0.6-1.1-1.70.2-0.4-0.8-1.2
Intermittent access day 1 locomotion1.21.24.60.60.11.0-1.01.0-1.01.8-1.0-2.1-0.81.0-1.00.80.2
Intermittent access day 15 total locomotion0.50.52.90.20.30.3-0.50.3-1.01.3-0.3-1.7-0.40.3-0.40.60.5
Intermittent access total locomotion0.30.31.5-0.50.8-0.20.1-0.2-0.70.80.2-1.2-0.3-0.30.20.30.6
Intermittent access standard deviation0.40.40.9-1.00.9-0.50.9-0.50.5-0.10.50.3-0.8-0.70.6-0.9-0.3
Cocaine induced anxiety0.70.82.71.1-1.20.1-1.10.1-1.30.1-0.1-0.70.90.5-0.31.61.1
Post-drug Anxiety0.10.20.40.4-0.50.3-0.10.30.6-0.3-0.30.6-0.10.3-0.3-0.1-0.6
Baseline Anxiety1.31.43.7-1.31.1-0.61.4-0.61.5-1.10.61.8-0.2-1.00.9-1.9-0.8
Lifetime Intake1.82.05.6-0.41.51.4-0.11.40.62.4-1.5-1.9-2.31.0-1.3-0.5-1.5
Incentive Sensitization - Responses0.40.40.90.5-0.20.7-0.60.7-0.30.9-0.7-1.0-0.30.8-0.80.5-0.2
Incentive Sensitization - Breakpoint0.40.41.10.6-0.30.7-0.70.7-0.50.9-0.7-1.0-0.20.8-0.80.6-0.1
Progressive ratio test 1 active lever presses1.92.06.3-0.11.21.4-0.41.40.02.5-1.4-2.4-2.01.1-1.40.0-1.1
Progressive ratio test 1 breakpoint1.81.95.8-0.21.31.4-0.31.40.22.4-1.4-2.2-2.01.1-1.3-0.1-1.2
Progressive ratio test 1 inactive lever presses2.93.17.10.80.42.2-1.12.20.22.7-2.2-2.3-2.02.0-2.20.4-1.6
Progressive ratio test 2 active lever presses1.61.74.60.60.31.5-0.91.5-0.42.1-1.5-2.1-1.41.4-1.50.5-0.7
Progressive ratio test 2 breakpoint1.51.74.80.60.21.4-1.01.4-0.62.1-1.5-2.2-1.21.3-1.40.7-0.5
Progressive ratio test 2 inactive lever presses0.50.62.3-0.41.00.50.10.50.31.2-0.6-1.0-1.50.3-0.5-0.1-0.7
Total sessions with >9 infusions2.83.07.40.90.22.0-1.32.0-0.42.7-2.0-2.6-1.91.9-2.10.5-1.0
Short access day 1 total inactive lever presses1.71.94.2-0.81.91.10.41.11.32.0-1.2-1.3-2.10.7-1.0-0.8-2.0
Short access day 10 total inactive lever presses0.00.00.2-0.20.2-0.10.3-0.10.4-0.00.10.2-0.0-0.10.0-0.1-0.4
Short access day 1 total infusions3.23.48.40.31.02.2-0.72.20.62.9-2.2-2.3-2.31.8-2.1-0.2-2.0
Short access day 10 total infusions2.12.35.80.11.01.7-0.61.70.42.4-1.8-2.0-2.11.4-1.7-0.1-1.5
Short access total infusions2.83.17.60.60.52.1-1.12.1-0.02.8-2.1-2.4-2.21.9-2.10.3-1.3
Short access day 1 locomotion0.91.02.30.50.31.2-0.91.2-0.61.5-1.2-1.5-0.81.1-1.10.4-0.3
Short access day 10 total locomotion0.30.31.1-0.40.2-0.70.2-0.7-0.8-0.40.7-0.00.4-0.70.80.31.1
Short access total locomotion0.90.92.30.20.61.1-0.51.10.01.5-1.1-1.3-1.30.9-1.00.2-0.7
Compulsive drug intake0.10.10.7-0.10.20.20.30.20.7-0.1-0.20.50.2-0.0-0.0-0.8-0.6
One hour access (0.3 mA shock)0.80.92.2-0.21.01.00.01.00.71.5-1.0-1.0-1.50.7-0.8-0.5-1.2
One hour access (shock baseline)1.41.64.7-0.21.11.2-0.21.20.32.2-1.2-1.9-2.11.0-1.2-0.2-1.2
Number of responses in last shaping day3.63.76.21.4-0.52.5-1.72.5-0.22.4-2.5-2.0-2.02.4-2.50.6-1.4
Context. condit. distance diff. score0.10.10.2-0.10.1-0.40.1-0.4-0.30.10.4-0.40.1-0.30.30.20.4
Locomotion velocity, session 15.86.211.71.7-0.43.4-2.03.40.33.0-3.4-2.3-2.33.1-3.20.4-2.0
Locomotion distance, session 11.41.83.70.9-0.21.9-1.01.90.41.5-1.9-1.0-1.31.7-1.8-0.1-1.3
Locomotion velocity, session 21.51.84.0-1.91.8-0.61.7-0.61.9-0.50.61.4-0.9-1.00.8-2.0-1.3
Locomotion distance, session 21.01.44.00.00.31.4-0.01.41.60.4-1.40.7-1.40.9-1.1-1.3-2.0
Locomotion velocity, session 31.31.52.71.0-0.51.6-1.11.6-0.11.4-1.6-1.1-1.31.5-1.60.4-0.8
Locomotion distance, session 31.71.95.3-0.71.61.20.51.21.51.6-1.2-0.7-2.30.7-1.0-1.2-2.1
Stereotopy head waving bouts, day 31.41.62.81.6-1.41.6-1.51.6-0.51.0-1.6-1.0-0.31.7-1.60.9-0.3
Stereotopy head waving duration, day 30.70.91.91.4-1.30.9-1.20.9-0.70.5-0.9-0.70.51.1-1.00.90.2
Locomotion velocity, session 70.00.00.10.1-0.1-0.1-0.1-0.1-0.30.00.1-0.10.00.00.00.30.2
Locomotion distance, session 70.20.20.5-0.20.50.50.10.50.40.5-0.5-0.2-0.70.3-0.4-0.3-0.7
Stereotopy head waving bouts, day 71.01.23.4-0.81.50.70.80.71.60.9-0.7-0.1-1.60.2-0.5-1.4-1.8
Stereotopy head waving duration, day 70.30.41.10.00.20.7-0.00.70.80.4-0.70.1-0.90.5-0.6-0.6-1.0
Locomotion velocity, session 80.70.91.61.2-1.11.3-1.11.3-0.10.4-1.3-0.1-0.51.3-1.20.3-0.5
Locomotion distance, session 80.50.71.50.6-0.31.2-0.61.20.30.9-1.2-0.4-0.81.1-1.1-0.1-0.9
Degree of sensitization distance0.80.82.40.7-1.3-0.5-0.6-0.5-1.1-1.00.50.41.6-0.10.41.01.3
Degree of sensitization stereotypy0.70.72.1-0.91.40.30.80.31.20.6-0.3-0.1-1.2-0.1-0.1-1.1-1.3
Condit. Reinf. active minus inactive responses0.40.41.1-0.70.6-0.40.8-0.40.9-0.50.40.9-0.4-0.60.5-1.0-0.5
Condit. Reinf. active-inactive response ratio0.30.41.00.3-0.6-0.6-0.3-0.5-0.8-0.70.60.10.9-0.30.40.71.0
Condit. Reinf. active responses1.62.05.2-1.71.6-0.51.7-0.62.2-0.60.51.6-1.3-1.00.8-2.3-1.5
Condit. Reinf. inactive responses2.12.56.0-1.91.6-0.82.0-0.92.4-1.00.82.1-1.1-1.31.1-2.5-1.5
Incentive salience index mean2.02.47.0-1.61.90.21.60.22.60.1-0.21.2-2.0-0.50.2-2.6-2.2
Condit. Reinf. lever presses4.56.117.0-1.92.91.41.91.34.11.1-1.41.2-3.70.1-0.7-3.8-4.0
Time in familiar zone, hab. session 13.53.36.4-1.71.1-2.51.7-2.5-0.2-1.72.50.91.6-2.32.4-0.21.4
Time in novel zone, hab. session 14.64.59.23.0-2.92.3-2.92.3-1.51.3-2.3-1.3-0.22.6-2.41.80.3
Total zone transitions, hab. session 10.00.00.2-0.1-0.1-0.10.1-0.10.1-0.40.10.50.2-0.10.1-0.10.0
Total locomotion distance, hab. session 11.21.73.0-1.40.8-1.41.5-1.41.0-1.61.41.70.6-1.51.5-1.20.1
Locomotion velocity, hab. session 11.52.23.9-1.91.4-1.11.9-1.11.8-1.31.12.0-0.1-1.51.4-2.0-0.8
Time in familiar zone, hab. session 21.61.73.1-0.5-0.3-1.70.7-1.7-0.6-1.71.71.01.7-1.41.60.21.5
Time in novel zone, hab. session 22.82.84.52.0-1.51.8-2.11.8-1.41.7-1.8-1.9-0.42.0-1.91.70.2
Total zone transitions, hab. session 20.50.61.40.10.21.1-0.21.10.80.6-1.1-0.0-0.80.8-0.9-0.6-1.2
Total locomotion distance, hab. session 20.30.51.3-0.80.80.00.80.01.2-0.2-0.00.7-0.4-0.30.2-1.1-0.9
Locomotion velocity, hab. session 20.50.71.9-1.01.1-0.11.0-0.11.4-0.20.10.9-0.5-0.40.3-1.4-1.1
Novel to familiar place preference ratio2.93.05.52.3-2.11.3-2.41.3-2.11.3-1.3-2.00.51.8-1.52.31.1
Novelty place preference3.23.36.42.4-2.31.1-2.41.1-2.41.2-1.1-2.00.81.7-1.42.51.5
Time in novel zone, NPP test3.84.07.92.7-2.61.2-2.71.2-2.71.2-1.2-2.11.01.8-1.52.81.7
Total zone transitions, NPP test0.71.02.00.30.11.4-0.41.40.90.8-1.4-0.0-1.11.0-1.2-0.6-1.4
Total locomotion distance, NPP test1.11.54.2-0.51.11.30.41.31.71.1-1.3-0.1-1.60.7-1.0-1.4-2.1
Locomotion velocity, NPP test1.21.74.9-0.91.61.00.81.02.01.0-1.00.1-1.70.4-0.7-1.8-2.2
Pavlov. Cond. lever latency3.24.011.01.8-2.4-0.8-1.7-0.7-3.3-0.50.8-1.23.10.10.33.13.2
Pavlov. Cond. magazine entry latency0.30.41.0-0.60.4-0.20.6-0.30.9-0.60.21.0-0.5-0.40.4-1.0-0.5
Pavlov. Cond. change in total contacts1.21.34.0-1.01.30.50.90.41.80.3-0.50.7-2.0-0.0-0.2-1.7-1.8
Pavlov. Cond. index score1.51.95.3-1.41.50.01.5-0.02.3-0.4-0.01.6-1.7-0.60.4-2.3-1.8
Pavlov. Cond. latency score1.41.74.9-1.41.60.11.40.02.2-0.2-0.11.4-1.8-0.50.3-2.2-1.8
Pavlov. Cond. lever contacts2.53.07.8-1.82.30.51.70.42.80.4-0.51.1-2.6-0.4-0.0-2.7-2.6
Pavlov. Cond. magazine entry number0.40.61.40.8-0.70.2-0.80.3-1.10.6-0.2-1.10.90.5-0.41.20.8
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.40.3-0.20.5-0.20.6-0.20.20.5-0.3-0.30.2-0.6-0.4
Pavlov. Cond. lever-magazine prob. diff.1.62.05.2-1.61.6-0.31.7-0.42.2-0.70.31.7-1.5-0.90.7-2.3-1.6
Pavlov. Cond. response bias1.41.84.9-1.41.60.21.30.12.2-0.2-0.21.2-1.9-0.40.2-2.1-1.9
Bone: apparent density0.71.13.0-1.41.7-0.41.4-0.41.60.00.40.6-1.0-0.80.5-1.5-1.2
Bone surface0.40.61.7-0.61.10.50.50.51.20.7-0.5-0.1-1.30.2-0.4-1.0-1.3
Bone volume0.30.51.4-0.91.20.10.80.11.10.3-0.10.1-1.0-0.20.0-1.0-1.1
Bone: connectivity density0.60.92.4-1.41.5-0.61.3-0.61.2-0.10.60.6-0.6-0.90.7-1.2-0.7
Bone: cortical apparent density1.31.73.4-1.10.5-1.91.2-1.9-0.2-1.51.91.01.1-1.71.7-0.11.0
Bone: cortical area1.32.04.0-1.91.8-0.81.9-0.82.0-0.80.81.5-0.9-1.21.0-2.0-1.3
Bone: cortical porosity0.20.20.50.5-0.6-0.1-0.4-0.1-0.7-0.10.1-0.10.60.10.10.50.7
Bone: cortical porosity0.00.00.1-0.00.10.00.00.00.00.3-0.0-0.2-0.10.0-0.0-0.1-0.0
Bone: cortical thickness1.21.93.7-1.91.7-1.51.9-1.51.2-1.01.51.1-0.1-1.71.5-1.3-0.4
Bone: cortical thickness0.30.30.6-0.2-0.1-0.80.2-0.8-0.4-0.80.80.30.7-0.60.60.40.6
Bone: cortical tissue density1.11.53.0-1.00.4-1.71.0-1.7-0.3-1.41.70.81.1-1.51.6-0.01.0
Bone: elastic displacement2.02.36.80.6-1.1-1.4-0.6-1.4-2.4-0.81.4-0.72.2-0.71.02.02.6
Bone: elastic work2.93.77.5-0.9-0.0-2.71.0-2.7-1.4-1.92.70.72.2-2.22.40.72.5
Bone: endosteal estimation0.51.13.2-0.10.51.20.11.21.40.6-1.20.5-1.50.7-0.9-1.1-1.8
Bone: endosteal perimeter0.81.54.00.00.61.5-0.11.51.41.0-1.50.0-1.81.1-1.3-1.1-2.0
Bone: final force0.50.82.2-0.80.8-0.00.9-0.01.5-0.60.01.4-0.9-0.40.2-1.4-1.2
Bone: final moment0.40.72.3-0.80.6-0.30.9-0.31.3-0.90.31.5-0.5-0.60.5-1.3-0.9
Bone: marrow area0.51.03.1-0.30.61.00.31.01.50.4-1.00.7-1.40.5-0.7-1.2-1.8
Bone: maximum diameter0.91.75.1-1.41.5-0.11.5-0.12.3-0.40.11.5-1.2-0.60.4-2.1-1.8
Bone: maximum force1.22.15.9-1.61.6-0.21.6-0.22.4-0.80.22.0-1.2-0.80.5-2.4-1.9
Bone: maximum moment1.11.94.7-1.51.4-0.51.6-0.52.1-1.00.52.0-0.9-1.00.8-2.2-1.5
Bone: minimum diameter0.10.10.2-0.40.1-0.50.3-0.5-0.0-0.40.50.40.4-0.40.5-0.00.3
Bone: periosteal estimation0.51.13.3-0.91.10.30.90.31.8-0.1-0.31.2-1.3-0.1-0.1-1.6-1.7
Bone: periosteal perimeter0.40.61.60.10.31.0-0.11.00.90.7-1.0-0.0-1.20.7-0.8-0.6-1.2
Bone: post-yield work0.70.92.7-0.10.31.10.11.11.50.4-1.10.6-1.20.6-0.8-1.2-1.7
Bone: stiffness1.62.57.4-1.51.3-0.11.6-0.12.7-1.10.12.6-1.2-0.70.5-2.6-2.0
Bone: tissue strength0.40.42.30.1-0.6-0.40.2-0.40.5-1.20.41.50.4-0.40.5-0.50.1
Bone: trabecular number0.91.42.7-1.61.6-0.71.6-0.71.6-0.50.71.1-0.8-1.10.9-1.6-1.0
Bone: trabecular spacing0.30.40.8-0.50.2-0.90.6-0.90.1-0.80.90.50.7-0.80.8-0.00.4
Bone: trabecular thickness0.00.00.10.0-0.1-0.20.0-0.2-0.2-0.00.2-0.00.3-0.20.20.10.4
Bone: trabecular tissue density0.91.23.6-0.70.50.30.90.31.9-0.8-0.31.8-1.1-0.20.0-1.9-1.7
Breakpoint value in progressive ratio session2.12.34.31.5-0.81.9-1.61.9-0.82.0-1.8-2.1-0.31.9-1.90.7-0.5
Distance traveled before self-admin2.02.26.9-0.61.21.20.61.12.21.2-1.2-0.0-2.40.7-1.1-1.7-2.6
Distance traveled after self-admin0.60.62.3-0.70.4-0.60.8-0.60.9-1.10.61.5-0.0-0.70.7-1.1-0.3
Delta time in closed arm before/after self-admin2.52.45.0-1.91.7-1.12.1-1.11.8-1.21.21.80.2-1.61.4-2.2-0.9
Delta time in open arm before/after self-admin0.80.71.41.0-0.90.8-1.10.8-0.81.0-0.8-1.2-0.30.9-0.90.70.2
Diff in mean of infusions in LGA sessions0.10.10.5-0.1-0.1-0.30.1-0.3-0.2-0.40.30.30.7-0.30.4-0.10.3
Extinction: sum of active levers before priming0.90.92.51.2-1.50.1-1.10.2-1.6-0.2-0.1-0.41.50.4-0.21.01.3
Active lever presses in extinction session 60.30.30.80.5-0.20.5-0.60.6-0.70.6-0.4-0.80.90.4-0.40.20.3
Delta distance traveled before/after self-admin0.70.72.10.6-1.1-0.6-0.4-0.5-0.8-1.30.70.91.4-0.40.60.81.2
Delta ambulatory time before/after self-admin1.31.43.40.9-1.6-0.8-0.7-0.7-1.4-1.60.81.01.8-0.40.71.21.8
Time in closed arm before self-admin0.91.03.40.8-0.8-0.2-1.0-0.2-1.80.30.1-1.30.70.3-0.11.91.6
Time in closed arm after self-admin0.40.40.6-0.40.2-0.80.4-0.8-0.3-0.80.80.40.7-0.70.80.30.6
Time in open arm before self-admin1.21.33.9-0.10.61.20.21.21.60.9-1.20.2-1.70.8-1.0-1.3-2.0
Time in open arm after self-admin1.31.43.9-0.10.81.2-0.01.21.11.6-1.3-0.8-2.00.9-1.1-1.1-1.7
Sum of active levers in priming session hrs 5-62.12.04.21.8-1.60.9-1.90.9-2.11.0-0.9-1.70.81.3-1.11.81.2
Time to tail flick, vehicle, before self-admin0.50.51.90.3-0.3-0.3-0.4-0.3-1.2-0.10.3-0.71.4-0.10.21.01.2
Time to tail flick, vehicle, after self-admin0.10.10.40.10.10.3-0.20.3-0.20.6-0.2-0.60.00.2-0.30.2-0.1
Time to tail flick, test, before self-admin0.30.30.7-0.80.8-0.50.8-0.60.6-0.10.40.3-0.5-0.60.5-0.5-0.3
Time to tail flick, test, after self-admin1.11.22.4-1.61.5-1.01.5-0.91.0-0.61.00.90.1-1.31.2-1.0-0.3
Delta time to tail flick, vehicle, before/after SA0.10.00.2-0.1-0.10.10.20.20.40.0-0.10.3-0.20.0-0.0-0.3-0.4
Delta time to tail flick, test, before/after SA0.10.10.1-0.20.2-0.30.2-0.2-0.2-0.20.30.00.3-0.30.30.10.3
Ambulatory time before self-admin2.22.36.4-0.31.11.50.21.51.81.7-1.5-0.7-2.51.1-1.4-1.5-2.5
Ambulatory time after self-admin0.10.10.30.1-0.00.2-0.00.20.4-0.2-0.20.6-0.40.2-0.2-0.5-0.4
Total heroin consumption1.21.52.61.3-0.81.3-1.41.3-0.91.5-1.3-1.6-0.11.5-1.50.8-0.1
Area under the delay curve0.60.61.11.0-0.80.8-1.10.8-0.80.7-0.8-0.90.40.9-0.90.70.2
Delay disc. indifference point, 0s delay1.01.12.11.4-1.30.7-1.40.7-1.20.6-0.7-1.10.91.0-0.91.40.8
Delay disc. indifference point, 16s delay2.22.24.31.7-1.21.5-1.81.5-1.31.7-1.5-2.1-0.11.8-1.71.40.2
Delay disc. indifference point, 2s delay0.20.30.4-0.60.4-0.60.5-0.60.2-0.50.60.50.6-0.60.6-0.20.2
Delay disc. indifference point, 24s delay0.10.10.40.4-0.7-0.0-0.3-0.0-0.4-0.40.00.20.30.1-0.00.30.4
Delay disc. indifference point, 4s delay0.00.00.30.2-0.10.1-0.30.1-0.3-0.0-0.1-0.10.60.1-0.10.30.2
Delay disc. indifference point, 8s delay0.00.00.10.0-0.00.2-0.00.20.10.0-0.20.1-0.10.1-0.1-0.3-0.2
Delay discount exponential model param0.50.50.9-0.90.7-0.81.0-0.80.7-0.70.80.9-0.3-0.90.8-0.6-0.2
Delay discount hyperbolic model param0.40.50.8-0.80.6-0.70.9-0.70.6-0.70.70.8-0.3-0.80.8-0.5-0.1
Fecal boli incidents, locomotor time 10.30.31.10.1-0.3-0.6-0.1-0.6-0.8-0.40.60.01.1-0.40.50.31.0
Change in fecal boli incidents, locomotor task1.11.02.80.10.41.2-0.11.10.91.3-1.2-0.8-1.70.9-1.1-0.1-1.5
Time >=10cm from walls, locomotor time 10.80.81.40.8-0.21.0-0.81.0-0.11.2-1.0-1.1-0.61.1-1.20.5-0.6
Bouts of movement, locomotor time 10.80.92.31.0-1.5-0.3-0.9-0.3-1.5-0.40.3-0.31.00.10.21.41.5
Total resting periods, locomotor time 11.11.23.70.8-1.4-0.8-0.6-0.8-1.6-0.90.80.11.4-0.40.71.41.9
Rest time, locomotor task time 13.53.97.9-0.6-0.7-2.50.9-2.5-1.0-2.82.52.02.2-2.12.40.62.4
Distance moved, locomotor task time 12.42.65.20.20.91.9-0.41.91.42.1-1.9-1.2-2.21.6-1.8-0.8-2.3
Vertical activity count, locomotor time 13.03.15.41.10.02.3-1.12.31.02.1-2.3-1.3-2.02.1-2.3-0.2-2.0
Time >=10cm from walls, locomotor time 20.10.10.20.1-0.10.3-0.10.30.30.1-0.30.2-0.40.2-0.3-0.2-0.4
Bouts of movement, locomotor time 20.20.20.8-0.60.50.10.50.10.80.1-0.10.4-0.4-0.10.0-0.9-0.7
Total resting periods, locomotor time 20.10.10.4-0.50.4-0.10.4-0.10.50.10.10.2-0.1-0.20.2-0.6-0.4
Rest time, locomotor task time 20.40.51.40.3-0.7-0.6-0.2-0.7-0.8-0.50.6-0.01.2-0.30.51.11.2
Distance moved, locomotor task time 20.60.62.2-0.80.4-0.60.9-0.60.8-1.10.61.5-0.3-0.80.8-0.9-0.2
Vertical activity count, locomotor time 20.20.30.60.2-0.10.5-0.00.50.8-0.3-0.50.8-0.60.3-0.4-0.7-0.8
Weight adjusted by age1.01.12.30.50.01.2-0.61.20.21.5-1.2-1.2-1.51.2-1.3-0.0-1.0
Seeking ratio, delayed vs. immediate footshock2.12.47.6-2.12.4-0.32.0-0.32.00.30.30.7-1.4-1.00.6-2.8-1.8
Locomotion in novel chamber0.50.61.1-0.80.6-0.90.8-0.90.1-0.80.90.80.7-1.01.0-0.40.5
Locomotion in novel chamber post-restriction2.53.04.9-2.11.7-1.62.2-1.61.7-1.81.62.10.3-2.01.9-1.8-0.4
Progressive ratio0.00.00.10.1-0.10.3-0.20.3-0.30.2-0.3-0.2-0.30.2-0.2-0.00.0
Food seeking constrained by brief footshock4.04.914.1-1.12.32.00.82.02.92.4-2.0-0.8-3.21.1-1.7-2.5-3.8
Seeking ratio, punishment vs. effort0.80.93.1-0.61.20.60.60.61.60.9-0.6-0.2-1.30.3-0.5-1.2-1.7
Run reversals in cocaine runway, females0.70.71.6-0.70.5-0.90.8-0.90.4-1.20.91.10.5-1.01.0-0.40.3
Run reversals in cocaine runway, males0.00.00.1-0.20.2-0.20.2-0.2-0.20.10.2-0.1-0.0-0.20.2-0.20.2
Latency to leave start box in cocaine runway0.40.51.4-1.01.2-0.41.0-0.40.9-0.30.40.5-0.4-0.60.5-0.8-0.6
Latency to leave start box in cocaine runway, F0.00.00.10.00.20.2-0.10.2-0.20.3-0.2-0.3-0.30.2-0.20.2-0.1
Latency to leave start box in cocaine runway, M0.60.51.9-0.30.70.60.30.61.20.6-0.6-0.1-1.00.4-0.5-0.7-1.4
Cd content in liver0.80.92.6-1.10.9-0.81.1-0.80.8-1.20.81.6-0.3-1.01.0-0.9-0.3
Co content in liver1.11.33.11.5-1.60.7-1.50.7-1.40.4-0.7-0.90.71.1-0.91.80.8
Cu content in liver1.11.33.30.4-1.1-1.1-0.2-1.1-1.1-1.71.11.01.8-0.60.91.01.6
Fe content in liver1.82.24.21.5-0.82.0-1.62.0-0.11.3-2.0-0.8-0.82.0-2.00.6-1.0
K content in liver0.60.61.11.0-0.80.8-1.00.8-0.50.4-0.8-0.50.00.9-0.90.90.1
Mg content in liver0.30.30.60.7-0.70.3-0.70.3-0.70.4-0.3-0.60.60.5-0.40.80.5
Mn content in liver0.60.71.2-0.90.6-0.81.0-0.80.4-0.90.81.10.7-1.01.0-0.70.1
Na content in liver1.11.23.91.4-2.0-0.1-1.2-0.1-1.2-1.00.10.51.60.3-0.01.41.4
Rb content in liver2.12.67.12.2-2.50.3-2.00.3-2.60.1-0.3-1.21.20.9-0.62.72.0
Se content in liver1.41.74.1-1.61.4-0.81.5-0.81.5-1.30.82.00.5-1.11.0-2.0-0.9
Sr content in liver0.30.31.2-0.50.4-0.10.6-0.10.7-0.30.10.60.7-0.30.3-1.1-0.6
Zn content in liver0.70.81.3-1.00.9-0.91.0-0.90.6-1.10.91.20.0-1.11.1-0.50.2