Hub : Genes

Eif4a3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000045791 0.19 0.09 0.0e+00 0.21 0.21 0.22 0.21 3.7e-23 4.3e-23 1.2e-23 3.8e-23
2 Adipose mRNA stability ENSRNOG00000045791 0.13 0.07 1.1e-16 0.15 0.16 0.16 0.16 5.0e-16 8.1e-18 7.6e-17 7.5e-17
3 Brain mRNA stability ENSRNOG00000045791 0.18 0.08 0.0e+00 0.21 0.2 0.2 0.2 6.7e-19 5.5e-18 2.9e-18 1.5e-18
4 IL mRNA stability ENSRNOG00000045791 0.22 0.14 8.2e-03 0.06 0.05 0.04 -0.01 1.6e-02 2.8e-02 3.4e-02 6.3e-01
5 LHb mRNA stability ENSRNOG00000045791 0.34 0.14 1.0e-05 0.12 0.07 0.1 0.12 1.0e-03 7.8e-03 2.1e-03 8.3e-04
6 Liver mRNA stability ENSRNOG00000045791 0.03 0.02 2.4e-03 0 0.01 0.01 0.01 8.9e-02 1.2e-02 1.9e-02 2.7e-02
7 NAcc gene expression ENSRNOG00000045791 0.05 0.03 2.0e-03 0.02 0.01 0.03 0 1.1e-02 2.7e-02 2.8e-03 3.5e-01
8 NAcc mRNA stability ENSRNOG00000045791 0.17 0.09 7.9e-09 0.12 0.05 0.12 -0 3.5e-09 1.9e-04 3.7e-09 8.4e-01
9 PL mRNA stability ENSRNOG00000045791 0.35 0.12 0.0e+00 0.35 0.3 0.35 0.19 2.9e-27 9.3e-23 1.5e-27 1.3e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.61.84.51.4-0.8-1.3-1.5-2.1-0.71.3-1.5-1.2
BMI without tail4.910.319.33.4-2.3-3.3-3.4-4.4-1.73.3-3.4-3.0
Body weight4.920.924.14.8-4.7-4.7-4.9-3.8-4.54.1-4.9-4.7
Epididymis fat weight1.73.95.02.1-1.7-2.1-2.1-2.2-1.52.0-2.1-1.9
Glucose3.65.47.8-2.52.12.52.42.82.0-1.92.42.2
Heart weight0.40.61.00.8-0.7-0.8-0.9-0.7-0.31.0-0.9-0.8
Left kidney weight0.41.14.30.6-1.6-0.8-0.70.7-2.10.3-0.7-0.9
Right kidney weight0.30.93.00.7-1.3-0.6-0.90.2-1.70.3-0.9-0.8
Tail length6.920.924.54.9-4.6-4.8-4.8-3.9-4.04.4-4.9-4.7
Length with tail3.914.220.33.9-4.5-3.8-3.9-1.9-4.43.0-3.9-4.0
Length without tail0.40.82.9-0.1-1.2-0.1-0.11.7-1.7-0.3-0.2-0.3
Liver weight, left0.20.21.1-0.4-0.40.20.31.0-0.8-0.00.40.1
Liver weight, right3.15.17.32.2-2.6-2.3-2.3-0.6-2.72.2-2.3-2.4
Parametrial fat weight1.83.54.42.0-2.0-2.0-2.0-1.3-1.51.8-2.0-2.1
Retroperitoneal fat weight6.621.925.15.0-4.5-5.0-4.9-4.4-3.94.7-4.9-4.8
Intraocular pressure0.40.51.10.8-0.1-0.6-1.0-1.10.30.4-1.0-0.6
Extensor digitorum longus weight0.20.63.50.40.6-0.4-0.4-1.91.00.2-0.3-0.0
Soleus weight1.54.55.72.3-1.9-2.4-2.4-1.4-1.32.2-2.4-2.4
Tibialis anterior weight0.00.10.6-0.20.40.20.1-0.10.7-0.50.10.3
Tibia length10.429.253.15.2-6.5-5.4-5.3-2.1-7.34.5-5.3-5.5
Number of licking bursts0.20.30.30.5-0.6-0.6-0.5-0.4-0.60.2-0.5-0.5
Food consumed during 24 hour testing period1.21.52.31.3-1.0-1.3-1.2-1.5-1.01.3-1.2-1.2
Times rat made contact with spout1.41.62.31.3-1.3-1.5-1.3-0.7-0.81.4-1.3-1.4
Mean time between licks in bursts1.21.72.3-1.41.21.51.41.11.1-1.11.41.4
Mean num. licks in bursts0.20.20.40.4-0.2-0.5-0.4-0.40.20.6-0.4-0.5
Std. dev. time between licks in bursts1.11.33.61.0-0.4-1.0-1.0-1.9-0.21.6-1.0-1.0
Water consumed over 24 hours0.00.00.2-0.0-0.2-0.20.00.4-0.00.30.0-0.2
Indifference point 0 sec0.30.51.10.8-0.1-0.6-0.8-1.10.50.8-0.8-0.7
Indifference point AUC0.00.00.10.1-0.0-0.1-0.2-0.30.2-0.1-0.2-0.1
Indifference point function ln k1.11.52.3-1.21.51.31.20.61.5-0.91.21.3
Indifference point function log k1.11.52.3-1.21.51.31.20.61.5-0.91.21.3
Delay discounting total patch changes 0 sec0.40.71.80.90.0-0.6-0.8-1.40.60.8-0.8-0.7
Delay discounting total patch changes 12 sec0.20.30.60.5-0.0-0.2-0.7-0.60.70.2-0.7-0.4
Delay discounting total patch changes 18 sec0.20.31.60.20.60.1-0.3-1.30.80.1-0.30.1
Delay discounting total patch changes 24 sec1.62.02.61.6-1.2-1.5-1.5-1.6-0.91.2-1.5-1.5
Delay discounting total patch changes 6 sec0.50.81.31.1-0.7-0.9-1.1-0.60.10.9-1.1-1.1
Delay discounting time to switch 0 sec0.91.42.0-1.20.91.41.11.30.5-1.41.11.3
Delay discounting water rate 0 sec4.36.89.82.8-2.0-2.8-2.7-3.1-1.62.7-2.7-2.6
Delay discounting water rate 12 sec0.50.73.00.70.2-0.7-0.4-1.70.51.1-0.4-0.6
Delay discounting water rate 18 sec1.92.55.31.5-0.9-1.8-1.5-2.3-0.41.9-1.5-1.5
Delay discounting water rate 24 sec4.15.714.72.5-1.2-2.3-2.4-3.8-0.52.7-2.4-2.1
Delay discounting water rate 6 sec0.30.51.60.6-0.2-0.9-0.5-1.3-0.10.9-0.5-0.6
Locomotor activity0.40.70.9-0.80.90.91.00.40.7-0.81.00.9
Locomotor testing distance0.20.40.6-0.60.70.70.70.00.5-0.60.70.6
Locomotor testing rearing0.20.31.40.40.2-0.2-0.3-1.20.30.5-0.3-0.2
Light reinforcement 12.03.66.62.0-1.1-2.0-1.9-2.3-0.62.6-1.9-2.0
Light reinforcement 22.93.85.92.0-1.8-2.2-1.8-1.6-1.62.4-1.8-2.1
Reaction time number correct0.91.37.20.90.2-0.9-0.8-2.70.81.1-0.8-0.5
Reaction time mean minus median0.20.31.2-0.50.10.50.51.1-0.0-0.60.50.4
Reaction time mean minus median AUC0.20.20.80.3-0.7-0.2-0.30.4-0.90.1-0.3-0.4
Reaction time num false alarms0.30.40.8-0.50.70.90.40.40.7-0.80.40.7
Reaction time num false alarms AUC0.60.91.5-0.81.01.20.70.61.0-1.20.71.1
Reaction time trials correct on left0.91.37.20.90.2-0.9-0.8-2.70.81.1-0.8-0.5
Reaction time trials on left1.01.47.50.90.2-1.0-0.8-2.70.71.1-0.8-0.5
Reaction time mean0.10.20.50.4-0.3-0.4-0.4-0.7-0.40.2-0.4-0.3
Reaction time mean AUC0.20.20.80.5-0.2-0.5-0.4-0.9-0.30.4-0.4-0.3
Median of all reaction times0.20.31.10.5-0.3-0.4-0.6-1.1-0.30.3-0.6-0.3
Reaction time omissions0.30.40.90.6-0.7-0.6-0.6-0.6-1.00.4-0.6-0.5
Reaction time false alarm rate1.21.63.6-1.20.81.61.01.90.6-1.61.01.2
Reaction time premature initiation rate1.72.34.0-1.41.81.71.31.02.0-1.41.31.6
Reaction time premature initiations1.01.44.8-0.71.81.00.7-0.72.2-0.70.71.1
Std. dev. reaction times0.40.61.0-0.70.70.80.70.50.6-1.00.70.8
Reaction time trials completed1.01.47.50.90.2-1.0-0.8-2.70.71.1-0.8-0.5
Reaction time trials AUC1.01.57.81.00.2-1.0-0.9-2.80.71.1-0.9-0.6
Social response proportion0.10.10.2-0.10.50.3-0.0-0.30.2-0.1-0.00.3
Social responses0.20.20.50.6-0.2-0.2-0.6-0.7-0.40.3-0.6-0.4
Social time0.10.10.2-0.00.5-0.00.0-0.50.40.10.00.1
Conditioned locomotion4.65.56.92.5-1.9-2.4-2.5-2.6-1.52.4-2.5-2.3
Cocaine response after cond. corrected0.10.10.1-0.40.20.30.40.20.2-0.10.40.3
Cocaine response after cond. not corrected0.70.71.0-1.00.70.91.00.90.5-0.71.00.9
Cocaine response before conditioning0.91.11.3-1.10.81.01.11.00.7-1.11.11.0
Saline control response2.93.94.92.0-2.2-2.1-2.0-1.3-1.91.7-2.0-2.1
Condit. Reinf. active minus inactive responses1.51.82.91.4-1.3-1.2-1.3-1.1-1.71.5-1.3-1.4
Condit. Reinf. active-inactive response ratio2.83.03.61.7-1.9-1.7-1.8-1.0-1.91.7-1.8-1.9
Condit. Reinf. active responses0.40.61.50.8-0.3-0.6-0.7-1.2-0.60.9-0.7-0.6
Condit. Reinf. inactive responses0.50.71.4-0.71.20.70.8-0.31.1-0.50.80.9
Condit. Reinf. lever presses0.40.63.00.70.1-0.6-0.7-1.70.20.6-0.7-0.4
Condit. Reinf. lever reinforcers received0.50.62.70.7-0.1-0.6-0.7-1.6-0.40.9-0.7-0.5
Pavlov. Cond. lever latency1.01.44.7-1.20.41.21.22.2-0.1-1.11.20.9
Pavlov. Cond. magazine entry latency1.31.43.0-0.91.61.01.0-0.71.7-1.31.01.3
Pavlov. Cond. change in total contacts0.30.51.7-0.11.00.20.2-1.31.1-0.20.20.4
Pavlov. Cond. index score0.30.42.50.20.7-0.1-0.1-1.60.9-0.1-0.10.2
Pavlov. Cond. latency score0.30.42.80.30.5-0.2-0.2-1.70.7-0.0-0.20.1
Pavlov. Cond. lever contacts1.31.95.61.4-0.6-1.4-1.4-2.4-0.21.3-1.4-1.1
Pavlov. Cond. magazine entry number0.91.12.80.6-1.5-0.7-0.81.0-1.70.9-0.8-1.0
Pavlov. Cond. intertrial magazine entries2.02.63.61.6-1.6-1.6-1.6-1.1-1.71.9-1.6-1.7
Pavlov. Cond. lever-magazine prob. diff.0.40.52.20.00.90.10.1-1.51.1-0.20.10.4
Pavlov. Cond. response bias0.40.63.30.60.3-0.5-0.5-1.80.60.5-0.5-0.3
Conditioned reinforcement - actives0.40.40.70.6-0.4-0.7-0.5-0.7-0.10.9-0.5-0.7
Conditioned reinforcement - inactives1.82.02.61.5-1.5-1.4-1.5-1.0-1.21.4-1.5-1.6
Conditioned locomotion0.70.91.51.0-0.9-1.0-0.9-0.7-0.31.2-1.0-1.2
Intermittent access intake day 1-15 change0.10.10.40.3-0.5-0.3-0.3-0.3-0.60.2-0.3-0.3
Intermittent access intake escalation0.20.20.40.5-0.6-0.5-0.5-0.4-0.60.4-0.5-0.5
Intermittent access intake escalation 20.60.61.00.6-1.0-0.8-0.7-0.3-1.00.6-0.7-0.7
Intermitt. access day 1 inactive lever presses2.42.63.01.7-1.7-1.6-1.7-1.2-1.61.5-1.7-1.6
Intermitt. access day 15 inactive lever presses2.02.23.01.6-1.2-1.7-1.5-1.7-0.91.7-1.5-1.5
Intermitt. access escalation Index2.01.82.11.4-1.3-1.4-1.4-1.2-1.11.4-1.4-1.4
Intermittent access day 1 total infusions0.30.30.60.6-0.4-0.5-0.5-0.5-0.00.8-0.6-0.7
Intermittent access day 15 total infusions0.70.81.01.0-0.9-0.8-0.9-0.8-0.61.0-1.0-1.0
Intermittent access terminal intake (last 3 days)1.11.21.61.1-1.2-1.1-1.1-0.8-0.91.2-1.1-1.3
Intermittent access total infusions0.70.71.10.9-0.8-0.7-0.9-0.8-0.41.0-0.9-1.0
Intermittent access day 1 locomotion0.90.91.41.1-0.8-0.8-1.1-0.9-0.21.1-1.2-1.1
Intermittent access day 15 total locomotion0.50.50.80.7-0.9-0.6-0.7-0.3-0.60.8-0.8-0.8
Intermittent access total locomotion0.91.11.51.1-0.9-1.0-1.2-0.9-0.51.2-1.2-1.1
Intermittent access standard deviation0.20.30.4-0.5-0.00.60.50.6-0.6-0.70.40.4
Cocaine induced anxiety5.56.37.82.5-2.8-2.4-2.7-1.7-2.72.3-2.7-2.6
Post-drug Anxiety1.31.42.71.2-1.1-0.7-1.6-1.2-1.20.8-1.7-1.0
Baseline Anxiety7.37.79.7-2.92.93.02.72.02.4-3.02.83.1
Lifetime Intake0.20.20.30.5-0.4-0.3-0.4-0.4-0.20.6-0.4-0.6
Incentive Sensitization - Responses0.00.00.10.1-0.3-0.2-0.00.1-0.30.1-0.0-0.3
Incentive Sensitization - Breakpoint0.00.00.10.0-0.3-0.2-0.00.1-0.30.1-0.0-0.3
Progressive ratio test 1 active lever presses0.90.91.41.0-0.8-1.1-0.8-0.9-0.41.2-0.9-1.1
Progressive ratio test 1 breakpoint1.01.01.71.1-0.8-1.2-0.9-1.0-0.41.3-0.9-1.2
Progressive ratio test 1 inactive lever presses4.24.55.12.3-2.0-2.2-2.2-2.0-1.82.3-2.2-2.2
Progressive ratio test 2 active lever presses0.50.50.80.8-0.7-0.7-0.7-0.5-0.40.8-0.8-0.9
Progressive ratio test 2 breakpoint0.60.60.90.9-0.8-0.8-0.8-0.7-0.50.9-0.8-1.0
Progressive ratio test 2 inactive lever presses0.70.81.10.9-1.0-0.9-0.9-0.6-0.80.9-1.0-1.0
Total sessions with >9 infusions0.50.61.0-0.80.60.91.00.70.3-0.70.90.7
Short access day 1 total inactive lever presses0.30.30.50.5-0.7-0.6-0.4-0.3-0.60.6-0.5-0.6
Short access day 10 total inactive lever presses4.34.85.52.2-2.3-2.2-2.3-1.8-2.22.1-2.3-2.2
Short access day 1 total infusions1.21.31.9-1.21.11.41.21.00.8-1.31.11.1
Short access day 10 total infusions0.60.61.10.8-0.9-0.8-0.7-0.5-0.61.0-0.7-1.0
Short access total infusions0.00.00.1-0.10.20.20.20.10.3-0.00.20.0
Short access day 1 locomotion0.30.31.0-0.70.20.60.61.00.1-0.70.50.4
Short access day 10 total locomotion0.20.20.7-0.50.00.50.40.80.0-0.50.30.3
Short access total locomotion0.70.71.7-1.00.40.90.91.30.4-0.90.80.7
Compulsive drug intake0.90.91.31.1-0.6-0.9-1.1-1.2-0.40.9-1.0-0.9
One hour access (0.3 mA shock)1.41.72.41.4-1.0-1.4-1.3-1.5-0.51.5-1.3-1.4
One hour access (shock baseline)0.30.30.50.5-0.6-0.7-0.4-0.3-0.40.7-0.4-0.7
Number of responses in last shaping day1.61.72.71.2-1.6-1.5-0.9-0.6-1.61.3-0.9-1.5
Context. condit. distance diff. score0.60.73.10.8-0.4-0.7-0.7-1.8-0.40.9-0.7-0.5
Locomotion velocity, session 13.73.97.1-2.21.42.02.22.70.7-2.02.21.9
Locomotion distance, session 12.12.74.0-1.72.01.71.60.71.8-1.51.61.8
Locomotion velocity, session 25.76.77.5-2.72.52.72.72.62.3-2.62.72.6
Locomotion distance, session 20.50.72.2-0.71.30.70.7-0.11.5-0.30.70.8
Locomotion velocity, session 31.51.82.8-1.61.01.41.41.70.7-1.11.41.3
Locomotion distance, session 33.84.25.3-2.32.12.02.21.61.7-2.02.22.2
Stereotopy head waving bouts, day 30.30.30.7-0.60.30.70.60.80.1-0.60.60.6
Stereotopy head waving duration, day 30.10.10.3-0.40.10.50.30.4-0.0-0.20.30.4
Locomotion velocity, session 70.80.91.3-1.10.90.91.10.50.6-0.91.11.0
Locomotion distance, session 73.13.95.7-2.02.41.92.00.22.3-1.82.02.2
Stereotopy head waving bouts, day 70.50.51.00.7-0.8-0.6-0.7-0.7-1.00.5-0.7-0.6
Stereotopy head waving duration, day 71.01.32.71.0-1.4-1.0-1.1-0.5-1.71.0-1.1-1.1
Locomotion velocity, session 80.20.20.3-0.30.40.50.4-0.5-0.1-0.50.40.6
Locomotion distance, session 80.50.84.50.50.5-0.5-0.4-2.10.70.8-0.4-0.1
Degree of sensitization distance0.80.82.51.0-0.4-0.8-0.9-1.60.11.0-0.9-0.7
Degree of sensitization stereotypy0.91.01.31.0-1.0-1.0-1.0-1.2-1.00.7-1.0-0.9
Condit. Reinf. active minus inactive responses2.42.73.81.8-1.4-1.7-1.8-1.6-1.12.0-1.8-1.7
Condit. Reinf. active-inactive response ratio1.11.21.91.2-0.8-1.1-1.2-1.4-0.61.2-1.2-1.0
Condit. Reinf. active responses4.04.96.12.4-2.0-2.4-2.4-2.0-1.52.5-2.4-2.3
Condit. Reinf. inactive responses0.91.01.31.1-0.9-1.2-1.1-0.9-0.61.1-1.1-1.1
Incentive salience index mean2.12.53.31.7-1.4-1.7-1.7-1.4-1.11.8-1.7-1.6
Condit. Reinf. lever presses0.10.10.30.4-0.1-0.4-0.3-0.5-0.00.4-0.3-0.3
Time in familiar zone, hab. session 10.10.10.5-0.20.40.20.2-0.00.7-0.00.20.2
Time in novel zone, hab. session 10.10.10.60.1-0.4-0.1-0.1-0.1-0.80.3-0.1-0.2
Total zone transitions, hab. session 10.30.41.1-0.40.90.50.4-0.31.1-0.60.40.7
Total locomotion distance, hab. session 10.50.72.50.8-0.2-0.7-0.8-1.60.11.0-0.8-0.6
Locomotion velocity, hab. session 10.40.62.20.9-0.2-0.7-0.8-1.50.20.8-0.8-0.6
Time in familiar zone, hab. session 20.20.20.4-0.30.50.40.4-0.20.7-0.30.40.4
Time in novel zone, hab. session 20.10.10.2-0.30.10.30.20.4-0.1-0.30.20.3
Total zone transitions, hab. session 20.40.52.2-0.21.10.30.3-0.91.5-0.10.30.5
Total locomotion distance, hab. session 20.70.93.00.90.1-0.8-0.8-1.70.61.3-0.8-0.6
Locomotion velocity, hab. session 20.91.23.31.2-0.2-1.1-1.1-1.80.31.4-1.1-0.9
Novel to familiar place preference ratio1.92.03.31.6-0.9-1.5-1.6-1.4-0.31.8-1.6-1.5
Novelty place preference1.81.92.91.5-0.9-1.4-1.6-1.3-0.41.7-1.6-1.4
Time in novel zone, NPP test1.51.62.51.4-0.8-1.3-1.5-1.3-0.21.6-1.5-1.3
Total zone transitions, NPP test0.40.51.6-0.41.10.50.4-0.81.3-0.10.40.7
Total locomotion distance, NPP test0.60.83.20.60.6-0.4-0.5-1.81.11.1-0.5-0.2
Locomotion velocity, NPP test0.50.82.90.70.4-0.6-0.7-1.70.91.2-0.7-0.4
Pavlov. Cond. lever latency0.91.22.2-0.91.50.91.1-1.01.3-0.81.11.1
Pavlov. Cond. magazine entry latency2.53.25.31.8-2.3-1.7-1.8-0.3-2.21.4-1.8-1.9
Pavlov. Cond. change in total contacts0.10.10.20.4-0.3-0.3-0.40.20.00.4-0.4-0.4
Pavlov. Cond. index score3.64.76.72.2-2.6-2.1-2.3-0.5-2.42.0-2.3-2.3
Pavlov. Cond. latency score2.83.65.81.8-2.4-1.8-2.00.0-2.21.7-2.0-2.1
Pavlov. Cond. lever contacts0.91.01.51.0-1.2-1.0-1.20.3-0.91.0-1.2-1.2
Pavlov. Cond. magazine entry number1.92.44.4-1.52.11.41.6-0.12.0-1.11.61.6
Pavlov. Cond. intertrial magazine entries0.20.20.80.30.4-0.3-0.2-0.90.70.4-0.2-0.1
Pavlov. Cond. lever-magazine prob. diff.3.94.86.52.3-2.5-2.2-2.4-0.7-2.32.0-2.4-2.4
Pavlov. Cond. response bias2.02.43.91.5-2.0-1.5-1.70.0-1.71.3-1.7-1.7
Bone: apparent density0.00.10.20.20.2-0.2-0.1-0.40.40.1-0.1-0.2
Bone surface0.10.20.40.3-0.6-0.4-0.40.2-0.60.3-0.4-0.6
Bone volume0.10.10.20.4-0.3-0.4-0.4-0.3-0.10.4-0.4-0.5
Bone: connectivity density0.10.10.3-0.30.50.30.3-0.10.6-0.30.30.3
Bone: cortical apparent density3.24.25.1-2.12.32.12.01.52.3-1.82.02.1
Bone: cortical area7.311.013.13.4-3.5-3.4-3.4-1.9-3.33.6-3.4-3.6
Bone: cortical porosity0.60.71.50.6-1.2-0.7-0.70.8-1.00.5-0.7-0.9
Bone: cortical porosity0.90.91.90.8-1.4-0.9-0.90.3-1.30.8-0.9-1.1
Bone: cortical thickness5.89.612.83.3-3.1-3.2-3.2-1.6-2.93.6-3.2-3.5
Bone: cortical thickness2.02.32.81.7-1.4-1.5-1.6-1.1-1.61.5-1.6-1.7
Bone: cortical tissue density3.74.85.8-2.32.42.22.21.62.4-2.02.22.3
Bone: elastic displacement1.82.03.31.5-1.1-1.5-1.5-1.1-0.71.8-1.5-1.6
Bone: elastic work6.78.811.43.1-3.0-3.1-3.2-1.6-2.53.1-3.2-3.4
Bone: endosteal estimation0.00.10.4-0.00.10.00.0-0.60.1-0.50.00.2
Bone: endosteal perimeter0.71.42.81.2-1.6-1.1-1.1-0.2-1.70.8-1.1-1.2
Bone: final force6.110.011.43.2-3.3-3.3-3.3-2.2-3.13.2-3.3-3.4
Bone: final moment7.011.513.23.5-3.5-3.6-3.6-2.3-3.23.5-3.6-3.6
Bone: marrow area0.00.10.4-0.00.10.00.0-0.60.1-0.40.00.2
Bone: maximum diameter2.24.17.52.0-2.5-2.0-1.9-0.7-2.71.7-1.9-2.1
Bone: maximum force5.810.111.83.3-3.2-3.3-3.3-2.2-3.03.3-3.3-3.4
Bone: maximum moment6.611.513.53.5-3.5-3.6-3.6-2.3-3.03.5-3.6-3.7
Bone: minimum diameter4.17.68.92.9-2.9-2.8-2.9-1.9-2.62.6-2.9-3.0
Bone: periosteal estimation2.24.55.12.2-2.2-2.2-2.2-1.6-2.12.0-2.2-2.3
Bone: periosteal perimeter3.55.88.92.3-3.0-2.3-2.3-0.3-3.02.3-2.3-2.6
Bone: post-yield work0.10.10.40.00.4-0.0-0.0-0.40.60.2-0.00.0
Bone: stiffness0.61.02.00.9-1.2-1.0-1.0-0.4-1.41.0-1.0-1.0
Bone: tissue strength2.22.23.01.6-1.0-1.6-1.6-1.7-0.41.7-1.6-1.5
Bone: trabecular number0.10.10.3-0.40.40.30.40.40.4-0.50.40.3
Bone: trabecular spacing1.31.76.51.3-0.6-1.0-1.1-2.6-0.91.5-1.1-0.7
Bone: trabecular thickness0.10.11.00.0-0.2-0.2-0.11.00.2-0.2-0.1-0.3
Bone: trabecular tissue density0.70.91.2-1.00.71.11.01.10.3-1.11.01.0
Breakpoint value in progressive ratio session0.70.81.31.0-0.6-1.0-1.0-1.1-0.30.9-1.0-0.9
Distance traveled before self-admin1.11.22.41.0-1.3-1.1-1.1-0.7-1.60.9-1.1-1.0
Distance traveled after self-admin0.80.92.30.9-0.2-1.2-0.8-1.50.21.2-0.8-0.7
Delta time in closed arm before/after self-admin0.20.20.60.3-0.6-0.3-0.40.2-0.80.1-0.4-0.4
Delta time in open arm before/after self-admin0.40.41.10.6-0.1-0.5-0.7-1.10.10.6-0.7-0.5
Diff in mean of infusions in LGA sessions0.00.00.0-0.0-0.0-0.0-0.2-0.1-0.0-0.1-0.2-0.0
Extinction: sum of active levers before priming1.11.11.7-1.11.31.01.10.61.2-1.11.11.1
Active lever presses in extinction session 60.30.30.50.6-0.4-0.5-0.7-0.7-0.40.5-0.7-0.5
Delta distance traveled before/after self-admin0.30.31.40.10.8-0.20.0-0.91.20.30.00.1
Delta ambulatory time before/after self-admin0.60.72.7-0.51.30.40.6-0.41.6-0.30.60.7
Time in closed arm before self-admin0.81.01.6-0.90.81.30.91.10.7-1.20.91.0
Time in closed arm after self-admin1.41.53.2-1.20.61.70.91.80.3-1.60.91.2
Time in open arm before self-admin0.10.10.2-0.1-0.2-0.40.40.3-0.40.10.4-0.0
Time in open arm after self-admin0.00.10.20.10.1-0.4-0.1-0.40.20.2-0.1-0.1
Sum of active levers in priming session hrs 5-60.30.30.80.6-0.2-0.8-0.4-0.9-0.10.7-0.4-0.5
Time to tail flick, vehicle, before self-admin0.10.10.10.4-0.3-0.4-0.3-0.2-0.10.3-0.3-0.4
Time to tail flick, vehicle, after self-admin2.02.22.8-1.51.21.61.51.71.1-1.61.51.4
Time to tail flick, test, before self-admin0.00.00.1-0.2-0.10.20.10.4-0.0-0.20.10.1
Time to tail flick, test, after self-admin0.10.10.40.1-0.20.2-0.2-0.1-0.6-0.2-0.2-0.1
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.10.40.20.1-0.10.5-0.10.10.2
Delta time to tail flick, test, before/after SA0.20.20.4-0.40.40.60.40.2-0.1-0.60.40.5
Ambulatory time before self-admin2.72.94.51.6-1.9-1.7-1.7-1.3-2.11.5-1.7-1.6
Ambulatory time after self-admin0.91.02.21.0-0.5-1.2-0.9-1.5-0.31.1-0.9-0.8
Total heroin consumption0.20.20.80.2-0.4-0.7-0.1-0.2-0.90.3-0.1-0.5
Area under the delay curve1.41.53.1-1.20.91.61.01.2-0.1-1.71.01.4
Delay disc. indifference point, 0s delay0.10.21.00.2-0.5-0.2-0.2-0.0-1.00.0-0.2-0.1
Delay disc. indifference point, 16s delay1.01.01.7-0.81.31.30.70.20.9-1.20.71.3
Delay disc. indifference point, 2s delay0.20.20.6-0.3-0.10.60.00.5-0.8-0.70.00.3
Delay disc. indifference point, 24s delay5.35.27.0-2.32.02.62.12.31.5-2.62.12.5
Delay disc. indifference point, 4s delay0.20.30.8-0.3-0.10.70.00.3-0.9-0.80.00.4
Delay disc. indifference point, 8s delay1.41.42.5-1.30.41.41.11.6-0.7-1.61.11.2
Delay discount exponential model param2.02.14.31.5-1.0-2.0-1.2-1.5-0.02.1-1.2-1.7
Delay discount hyperbolic model param1.71.83.91.4-0.9-1.9-1.0-1.30.12.0-1.0-1.5
Fecal boli incidents, locomotor time 10.70.81.7-0.81.10.81.00.41.3-0.51.00.8
Change in fecal boli incidents, locomotor task4.13.95.1-2.11.82.31.81.91.7-2.21.82.1
Time >=10cm from walls, locomotor time 10.10.10.60.00.3-0.30.0-0.80.10.10.0-0.0
Bouts of movement, locomotor time 12.42.73.0-1.61.71.71.71.31.7-1.61.71.6
Total resting periods, locomotor time 13.13.43.8-1.91.91.91.91.62.0-1.81.91.8
Rest time, locomotor task time 10.30.40.8-0.60.40.60.60.90.6-0.40.60.4
Distance moved, locomotor task time 10.91.01.21.0-1.0-1.0-1.1-0.9-1.00.8-1.1-1.0
Vertical activity count, locomotor time 11.11.22.21.2-0.7-1.5-0.9-1.4-0.71.0-0.9-1.1
Time >=10cm from walls, locomotor time 20.10.10.20.2-0.2-0.1-0.4-0.0-0.00.1-0.4-0.2
Bouts of movement, locomotor time 21.61.72.1-1.31.41.41.30.91.1-1.41.31.3
Total resting periods, locomotor time 20.91.01.3-1.01.11.11.00.70.9-1.11.01.0
Rest time, locomotor task time 20.10.20.3-0.40.30.50.40.50.4-0.50.40.3
Distance moved, locomotor task time 20.40.51.00.6-0.8-0.5-0.8-0.3-1.00.4-0.8-0.6
Vertical activity count, locomotor time 20.40.40.80.8-0.4-0.6-0.6-0.9-0.60.5-0.6-0.6
Weight adjusted by age3.94.35.22.1-2.2-2.2-2.0-1.6-1.92.3-2.2-2.2
Seeking ratio, delayed vs. immediate footshock1.01.21.61.1-1.2-1.1-1.1-0.5-1.31.2-1.1-1.1
Locomotion in novel chamber0.10.10.30.3-0.1-0.1-0.5-0.50.10.2-0.5-0.1
Locomotion in novel chamber post-restriction0.60.81.10.9-1.0-1.0-0.9-0.4-0.41.0-0.8-1.0
Progressive ratio0.50.51.1-0.70.90.70.60.51.0-0.60.60.8
Food seeking constrained by brief footshock0.10.10.2-0.40.30.30.30.20.1-0.30.30.4
Seeking ratio, punishment vs. effort0.20.20.70.3-0.5-0.4-0.3-0.5-0.80.3-0.3-0.4
Run reversals in cocaine runway, females0.60.61.2-0.71.10.90.5-0.20.9-0.80.51.0
Run reversals in cocaine runway, males0.30.30.70.5-0.9-0.6-0.40.1-0.50.5-0.4-0.7
Latency to leave start box in cocaine runway0.91.01.7-1.01.10.61.20.71.3-0.71.10.9
Latency to leave start box in cocaine runway, F0.20.20.8-0.40.60.20.4-0.00.9-0.30.40.4
Latency to leave start box in cocaine runway, M0.50.51.1-0.70.70.30.90.61.0-0.30.70.6
Cd content in liver1.21.42.4-1.21.61.31.1-0.01.3-1.01.11.4
Co content in liver0.10.10.6-0.10.50.10.2-0.50.80.10.10.2
Cu content in liver0.10.10.20.3-0.5-0.3-0.30.4-0.30.4-0.3-0.5
Fe content in liver0.60.70.9-0.90.80.90.80.40.9-0.70.90.9
K content in liver2.52.53.51.7-1.5-1.9-1.6-1.4-1.21.6-1.6-1.7
Mg content in liver0.20.20.90.40.1-0.6-0.3-1.00.50.5-0.3-0.3
Mn content in liver0.30.31.10.5-0.8-0.5-0.30.1-1.00.5-0.3-0.5
Na content in liver0.10.10.20.1-0.3-0.10.00.4-0.40.20.1-0.2
Rb content in liver1.11.43.11.3-0.6-1.2-1.3-1.8-0.31.3-1.3-1.1
Se content in liver0.30.40.70.7-0.5-0.7-0.6-0.8-0.40.6-0.6-0.7
Sr content in liver0.40.41.7-0.40.20.60.31.30.2-0.80.30.3
Zn content in liver0.10.21.2-0.2-0.20.10.21.1-0.2-0.20.2-0.1