Hub : Genes

Fasn

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000045636 0.04 0.03 4.1e-05 0.03 0.03 0.04 0.03 1.2e-04 1.7e-04 5.1e-05 5.4e-04
2 Adipose mRNA stability ENSRNOG00000045636 0.06 0.03 8.7e-08 0.06 0.06 0.06 0.06 9.2e-08 3.2e-07 2.0e-07 1.5e-07
3 Brain gene expression ENSRNOG00000045636 0.06 0.04 2.5e-05 0.05 0.05 0.05 0.05 2.6e-05 1.8e-05 3.1e-05 1.3e-05
4 Liver mRNA stability ENSRNOG00000045636 0.03 0.02 4.0e-03 0.02 0.02 0.02 0.02 1.6e-03 1.8e-03 3.1e-03 2.7e-03
5 NAcc gene expression ENSRNOG00000045636 0.03 0.03 7.9e-03 0.01 0.02 0.01 0 5.8e-02 1.4e-02 4.1e-02 1.2e-01
6 OFC gene expression ENSRNOG00000045636 0.16 0.11 8.2e-03 0.02 0.04 -0.01 -0.01 1.0e-01 4.7e-02 9.3e-01 4.8e-01
7 PL gene expression ENSRNOG00000045636 0.04 0.03 4.6e-03 0.02 0.03 0.03 0.03 8.2e-03 5.0e-03 1.9e-03 4.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.30.91.9-0.10.4-1.11.1-1.1-1.4-0.9
BMI without tail5.912.418.03.53.9-3.24.2-3.2-4.0-2.2
Body weight2.611.117.22.43.0-3.92.2-4.0-4.2-3.2
Epididymis fat weight0.61.52.51.21.0-1.21.3-1.4-1.6-0.7
Glucose3.55.316.9-2.3-2.51.2-4.11.42.20.0
Heart weight0.40.61.5-0.10.6-0.90.1-0.8-0.9-1.2
Left kidney weight0.10.31.0-1.0-0.2-0.2-0.4-0.2-0.1-0.7
Right kidney weight0.10.31.7-1.3-0.60.2-0.10.20.20.0
Tail length6.318.925.14.95.0-4.14.1-4.2-4.7-3.0
Length with tail1.86.79.92.32.4-3.01.1-3.1-3.0-2.5
Length without tail1.32.78.3-2.3-2.00.4-2.90.41.1-0.2
Liver weight, left0.40.62.8-0.8-0.70.1-1.70.10.4-0.4
Liver weight, right1.22.12.91.31.2-1.70.6-1.7-1.7-1.5
Parametrial fat weight1.73.44.52.12.1-1.91.2-1.9-1.9-1.6
Retroperitoneal fat weight4.013.417.34.24.0-3.62.5-4.0-4.1-3.0
Intraocular pressure0.91.32.21.51.4-1.11.2-1.0-1.2-0.6
Extensor digitorum longus weight0.20.73.80.40.60.12.00.0-0.50.6
Soleus weight1.44.04.82.22.2-2.01.5-2.0-2.2-1.6
Tibialis anterior weight0.10.41.40.70.7-0.11.2-0.1-0.40.1
Tibia length7.120.132.72.93.3-5.70.5-5.5-5.1-5.7
Number of licking bursts0.20.20.80.50.4-0.10.9-0.2-0.40.2
Food consumed during 24 hour testing period0.60.72.01.41.0-0.70.6-0.7-0.7-0.3
Times rat made contact with spout2.02.34.32.11.8-1.4-0.4-1.5-1.1-1.7
Mean time between licks in bursts1.52.12.7-1.6-1.41.6-0.41.61.61.6
Mean num. licks in bursts0.50.61.20.80.8-0.8-0.8-0.7-0.4-1.1
Std. dev. time between licks in bursts1.11.36.80.70.8-0.22.6-0.2-0.90.7
Water consumed over 24 hours0.10.20.90.10.00.1-1.0-0.00.3-0.3
Indifference point 0 sec0.10.10.30.40.6-0.20.3-0.4-0.3-0.1
Indifference point AUC0.10.10.40.30.6-0.20.5-0.1-0.2-0.2
Indifference point function ln k1.31.83.1-1.5-1.81.3-0.61.31.31.4
Indifference point function log k1.31.83.1-1.5-1.81.3-0.61.31.31.4
Delay discounting total patch changes 0 sec0.10.10.30.30.5-0.20.4-0.3-0.3-0.0
Delay discounting total patch changes 12 sec0.10.10.50.40.7-0.30.1-0.3-0.2-0.4
Delay discounting total patch changes 18 sec0.10.20.6-0.20.30.30.80.30.10.5
Delay discounting total patch changes 24 sec0.40.50.80.60.9-0.70.6-0.8-0.8-0.7
Delay discounting total patch changes 6 sec0.40.61.10.71.0-0.70.2-0.9-0.7-0.8
Delay discounting time to switch 0 sec0.40.60.8-0.5-0.70.9-0.60.80.90.7
Delay discounting water rate 0 sec1.93.04.31.61.8-1.91.5-1.9-2.1-1.4
Delay discounting water rate 12 sec0.10.20.8-0.40.1-0.40.9-0.3-0.6-0.1
Delay discounting water rate 18 sec0.40.51.90.20.5-0.51.4-0.5-0.9-0.1
Delay discounting water rate 24 sec1.31.83.90.81.2-1.22.0-1.2-1.7-0.6
Delay discounting water rate 6 sec0.10.20.4-0.7-0.4-0.10.7-0.0-0.30.1
Locomotor activity0.91.42.4-1.6-1.41.1-0.91.11.21.0
Locomotor testing distance1.42.33.2-1.7-1.81.6-0.61.51.41.6
Locomotor testing rearing0.30.51.1-0.4-0.60.9-0.10.90.81.0
Light reinforcement 10.91.63.01.51.3-1.01.7-1.1-1.5-0.5
Light reinforcement 21.41.83.01.21.2-1.51.2-1.5-1.7-1.0
Reaction time number correct1.01.57.80.00.30.52.80.5-0.41.4
Reaction time mean minus median0.20.31.5-0.2-0.30.2-1.20.10.4-0.1
Reaction time mean minus median AUC0.10.10.4-0.1-0.3-0.0-0.6-0.00.1-0.1
Reaction time num false alarms0.10.20.30.0-0.10.6-0.20.50.60.3
Reaction time num false alarms AUC0.40.61.1-0.3-0.51.0-0.21.01.00.8
Reaction time trials correct on left1.01.57.80.00.30.52.80.5-0.41.4
Reaction time trials on left1.11.68.10.00.30.52.80.5-0.41.4
Reaction time mean0.20.30.60.70.8-0.50.3-0.5-0.6-0.5
Reaction time mean AUC0.20.20.50.50.7-0.30.7-0.3-0.5-0.1
Median of all reaction times0.30.40.60.60.8-0.50.7-0.5-0.7-0.4
Reaction time omissions0.10.10.40.50.50.00.6-0.1-0.20.3
Reaction time false alarm rate0.50.72.4-0.3-0.50.7-1.60.61.0-0.1
Reaction time premature initiation rate0.71.01.6-0.8-0.81.1-0.41.31.31.0
Reaction time premature initiations0.81.22.6-0.6-0.51.21.11.30.91.6
Std. dev. reaction times0.20.30.5-0.4-0.40.7-0.50.70.70.5
Reaction time trials completed1.11.68.10.00.30.52.80.5-0.41.4
Reaction time trials AUC1.11.68.20.10.40.52.90.4-0.41.4
Social response proportion0.60.61.0-0.9-0.90.70.10.80.71.0
Social responses0.50.61.2-0.7-1.00.80.20.60.61.1
Social time0.30.40.8-0.8-0.90.50.10.50.40.6
Conditioned locomotion4.45.26.62.52.5-2.22.3-2.2-2.6-1.5
Cocaine response after cond. corrected0.10.10.5-0.4-0.40.0-0.70.00.2-0.2
Cocaine response after cond. not corrected0.50.50.9-0.8-0.90.5-0.80.60.80.4
Cocaine response before conditioning0.91.21.8-1.0-1.11.20.01.21.11.3
Saline control response2.73.54.81.91.9-2.11.2-2.1-2.2-1.6
Condit. Reinf. active minus inactive responses0.91.11.60.71.0-1.30.8-1.1-1.3-1.1
Condit. Reinf. active-inactive response ratio2.42.53.71.21.5-1.90.4-1.8-1.7-1.9
Condit. Reinf. active responses0.30.40.60.50.6-0.70.8-0.5-0.7-0.5
Condit. Reinf. inactive responses0.40.50.8-0.6-0.70.70.10.80.70.9
Condit. Reinf. lever presses0.20.30.90.60.6-0.51.0-0.4-0.6-0.1
Condit. Reinf. lever reinforcers received0.30.40.90.50.6-0.71.0-0.5-0.7-0.3
Pavlov. Cond. lever latency0.60.81.9-0.9-1.00.7-1.40.61.00.2
Pavlov. Cond. magazine entry latency1.61.93.3-1.1-1.21.60.41.61.31.8
Pavlov. Cond. change in total contacts0.20.30.7-0.2-0.20.50.60.50.30.8
Pavlov. Cond. index score0.20.20.6-0.0-0.20.40.70.50.20.8
Pavlov. Cond. latency score0.20.20.80.0-0.10.40.90.40.10.8
Pavlov. Cond. lever contacts0.91.32.71.21.3-0.91.6-0.8-1.2-0.3
Pavlov. Cond. magazine entry number1.21.53.10.91.1-1.4-0.5-1.4-1.1-1.8
Pavlov. Cond. intertrial magazine entries1.92.53.11.51.8-1.71.1-1.6-1.8-1.5
Pavlov. Cond. lever-magazine prob. diff.0.20.30.8-0.1-0.30.60.60.60.40.9
Pavlov. Cond. response bias0.20.21.00.30.2-0.11.0-0.1-0.40.4
Conditioned reinforcement - actives0.20.20.80.2-0.00.20.90.2-0.10.4
Conditioned reinforcement - inactives1.21.41.91.11.1-1.40.7-1.3-1.3-1.3
Conditioned locomotion0.10.10.70.30.20.10.8-0.0-0.10.1
Intermittent access intake day 1-15 change1.71.74.12.01.4-1.30.7-1.2-1.1-1.0
Intermittent access intake escalation1.61.54.32.11.3-1.10.9-1.0-1.0-0.6
Intermittent access intake escalation 22.32.33.31.61.5-1.7-0.3-1.7-1.4-1.8
Intermitt. access day 1 inactive lever presses0.90.91.60.60.8-1.30.2-1.3-1.1-1.0
Intermitt. access day 15 inactive lever presses0.91.01.61.31.0-1.00.9-0.9-1.1-0.6
Intermitt. access escalation Index1.11.02.41.41.1-0.61.6-0.6-0.90.0
Intermittent access day 1 total infusions0.50.51.40.60.7-0.61.2-0.7-0.8-0.4
Intermittent access day 15 total infusions1.31.52.81.71.3-1.01.5-1.0-1.1-0.6
Intermittent access terminal intake (last 3 days)1.81.93.31.81.6-1.31.4-1.3-1.3-0.9
Intermittent access total infusions0.91.02.11.21.0-0.81.5-0.9-1.0-0.4
Intermittent access day 1 locomotion0.30.31.30.30.3-0.41.2-0.4-0.60.1
Intermittent access day 15 total locomotion0.60.71.00.81.0-0.71.0-0.8-0.8-0.6
Intermittent access total locomotion0.50.61.30.70.7-0.71.1-0.7-0.7-0.3
Intermittent access standard deviation0.60.72.8-0.7-1.00.2-1.70.20.6-0.1
Cocaine induced anxiety4.04.711.10.91.3-2.5-1.3-2.6-2.0-3.3
Post-drug Anxiety0.70.72.40.10.2-1.0-0.8-0.9-0.6-1.6
Baseline Anxiety6.36.710.0-2.0-2.52.90.13.12.93.2
Lifetime Intake0.40.41.30.80.5-0.41.2-0.4-0.5-0.1
Incentive Sensitization - Responses0.80.81.31.20.9-0.81.0-0.6-0.7-0.8
Incentive Sensitization - Breakpoint0.60.61.11.00.9-0.70.9-0.6-0.6-0.8
Progressive ratio test 1 active lever presses1.31.42.01.41.3-1.01.3-1.1-1.2-0.6
Progressive ratio test 1 breakpoint1.81.82.61.61.5-1.21.4-1.4-1.4-0.9
Progressive ratio test 1 inactive lever presses2.12.23.21.41.5-1.61.5-1.6-1.8-1.1
Progressive ratio test 2 active lever presses0.80.81.41.21.0-0.81.1-0.8-0.8-0.7
Progressive ratio test 2 breakpoint0.91.01.91.31.1-0.81.4-0.8-0.9-0.5
Progressive ratio test 2 inactive lever presses0.40.50.60.60.6-0.80.4-0.8-0.7-0.7
Total sessions with >9 infusions0.30.40.9-0.2-0.50.60.90.60.50.7
Short access day 1 total inactive lever presses0.30.30.9-0.4-0.20.40.90.40.10.8
Short access day 10 total inactive lever presses3.13.45.41.41.7-2.30.6-2.2-2.2-1.9
Short access day 1 total infusions1.81.92.5-1.6-1.51.6-0.21.51.51.3
Short access day 10 total infusions0.80.91.21.11.0-0.81.1-0.9-0.8-0.8
Short access total infusions0.10.10.50.30.20.00.7-0.0-0.00.0
Short access day 1 locomotion0.40.51.0-1.0-0.70.7-0.20.70.80.2
Short access day 10 total locomotion0.10.20.5-0.7-0.40.1-0.50.10.4-0.0
Short access total locomotion0.30.30.6-0.8-0.60.5-0.10.50.70.3
Compulsive drug intake0.20.20.40.10.4-0.60.1-0.6-0.7-0.5
One hour access (0.3 mA shock)2.02.32.91.71.6-1.41.7-1.4-1.6-1.2
One hour access (shock baseline)0.60.72.51.20.7-0.41.6-0.4-0.6-0.0
Number of responses in last shaping day0.50.51.10.60.6-0.71.0-0.7-0.8-0.4
Context. condit. distance diff. score1.01.24.71.11.3-0.32.2-0.4-0.90.1
Locomotion velocity, session 11.81.93.9-1.3-1.31.2-2.01.31.70.5
Locomotion distance, session 12.53.24.5-1.8-1.62.10.32.11.82.1
Locomotion velocity, session 24.45.26.6-2.4-2.52.3-1.62.42.62.0
Locomotion distance, session 20.50.71.2-0.7-0.40.90.90.90.61.1
Locomotion velocity, session 32.12.43.1-1.8-1.61.6-1.61.51.81.1
Locomotion distance, session 33.63.95.0-2.2-2.12.1-1.12.12.21.9
Stereotopy head waving bouts, day 30.60.71.3-1.1-0.80.7-1.10.80.90.3
Stereotopy head waving duration, day 30.40.51.1-1.1-0.60.7-0.60.60.70.4
Locomotion velocity, session 70.80.81.2-0.7-0.91.1-0.21.01.01.1
Locomotion distance, session 72.63.35.8-1.4-1.62.10.52.21.82.4
Stereotopy head waving bouts, day 70.10.10.1-0.10.3-0.20.2-0.3-0.4-0.3
Stereotopy head waving duration, day 70.20.20.40.10.5-0.50.1-0.6-0.6-0.5
Locomotion velocity, session 80.50.61.0-0.7-0.60.71.00.90.51.0
Locomotion distance, session 81.11.68.60.40.90.32.90.3-0.51.0
Degree of sensitization distance1.01.12.11.41.1-0.81.4-0.7-1.0-0.4
Degree of sensitization stereotypy0.30.30.50.30.6-0.50.5-0.6-0.7-0.5
Condit. Reinf. active minus inactive responses2.52.83.41.91.7-1.81.2-1.7-1.8-1.6
Condit. Reinf. active-inactive response ratio0.80.81.20.80.8-1.10.6-1.0-1.1-0.9
Condit. Reinf. active responses4.85.97.72.82.6-2.51.9-2.4-2.6-2.1
Condit. Reinf. inactive responses1.82.13.71.91.7-1.41.2-1.3-1.4-1.1
Incentive salience index mean2.02.43.51.91.7-1.51.4-1.5-1.7-1.2
Condit. Reinf. lever presses0.10.20.70.50.30.20.90.1-0.10.5
Time in familiar zone, hab. session 10.10.10.3-0.0-0.1-0.3-0.6-0.10.0-0.5
Time in novel zone, hab. session 10.00.00.1-0.10.00.20.40.1-0.00.3
Total zone transitions, hab. session 10.30.40.6-0.8-0.60.70.10.80.60.6
Total locomotion distance, hab. session 10.10.10.80.10.20.00.9-0.0-0.20.1
Locomotion velocity, hab. session 10.10.20.90.20.30.10.9-0.0-0.20.1
Time in familiar zone, hab. session 20.20.20.40.0-0.10.50.20.50.50.6
Time in novel zone, hab. session 20.10.10.5-0.7-0.50.1-0.20.20.10.1
Total zone transitions, hab. session 20.50.72.7-0.40.00.71.60.70.20.9
Total locomotion distance, hab. session 20.81.05.30.60.9-0.22.3-0.2-0.80.4
Locomotion velocity, hab. session 20.91.35.50.81.1-0.42.4-0.5-1.00.1
Novel to familiar place preference ratio2.42.54.41.21.2-1.9-0.4-1.9-1.6-2.1
Novelty place preference2.42.44.41.21.1-1.9-0.5-1.9-1.6-2.1
Time in novel zone, NPP test1.92.03.61.01.0-1.7-0.3-1.7-1.5-1.9
Total zone transitions, NPP test0.91.33.7-0.3-0.21.11.91.10.51.6
Total locomotion distance, NPP test0.81.26.10.40.50.42.50.3-0.31.1
Locomotion velocity, NPP test0.60.94.80.60.70.12.20.0-0.50.7
Pavlov. Cond. lever latency0.91.12.1-0.7-0.71.11.11.20.81.4
Pavlov. Cond. magazine entry latency2.53.25.31.71.5-2.1-0.7-2.0-1.6-2.3
Pavlov. Cond. change in total contacts0.50.51.80.10.1-0.6-1.3-0.6-0.2-1.0
Pavlov. Cond. index score2.83.55.01.81.8-2.2-0.2-2.2-1.9-2.2
Pavlov. Cond. latency score2.22.84.41.61.6-1.9-0.5-2.0-1.6-2.1
Pavlov. Cond. lever contacts0.60.71.00.80.7-0.9-0.4-1.0-0.7-1.0
Pavlov. Cond. magazine entry number2.43.05.8-1.5-1.32.01.31.91.42.4
Pavlov. Cond. intertrial magazine entries0.60.72.20.90.9-0.41.5-0.4-0.7-0.0
Pavlov. Cond. lever-magazine prob. diff.2.93.65.11.81.8-2.2-0.2-2.2-1.9-2.3
Pavlov. Cond. response bias2.02.44.31.31.1-1.9-1.0-1.8-1.3-2.1
Bone: apparent density0.10.20.70.30.5-0.30.8-0.4-0.5-0.2
Bone surface0.30.50.91.00.9-0.60.5-0.7-0.7-0.6
Bone volume0.30.50.80.80.9-0.60.7-0.6-0.7-0.5
Bone: connectivity density0.20.21.20.30.30.31.10.2-0.10.5
Bone: cortical apparent density2.53.24.3-1.9-1.81.9-1.41.92.11.6
Bone: cortical area4.06.19.81.11.8-3.10.9-3.1-3.0-3.1
Bone: cortical porosity1.41.54.00.20.1-1.2-2.0-1.2-0.6-1.8
Bone: cortical porosity1.31.43.20.50.4-1.3-1.5-1.3-0.8-1.8
Bone: cortical thickness3.35.510.90.51.3-3.10.1-2.9-2.7-3.3
Bone: cortical thickness1.11.22.5-0.30.3-1.6-0.0-1.4-1.3-1.6
Bone: cortical tissue density2.83.74.9-1.9-1.92.1-1.52.02.21.7
Bone: elastic displacement1.01.21.80.70.9-1.3-0.0-1.4-1.2-1.4
Bone: elastic work5.97.614.01.72.0-3.5-0.4-3.4-2.9-3.7
Bone: endosteal estimation0.10.31.40.30.50.21.20.1-0.20.5
Bone: endosteal perimeter0.61.31.91.41.2-1.10.6-1.2-1.2-1.1
Bone: final force3.76.110.10.91.8-3.21.1-3.1-3.1-2.9
Bone: final moment4.47.211.81.22.0-3.41.0-3.3-3.3-3.2
Bone: marrow area0.10.31.30.30.40.21.10.1-0.20.5
Bone: maximum diameter0.91.62.60.71.0-1.50.7-1.6-1.6-1.5
Bone: maximum force4.07.011.31.22.0-3.41.4-3.2-3.3-3.0
Bone: maximum moment4.78.113.01.52.2-3.61.3-3.4-3.5-3.3
Bone: minimum diameter2.44.46.21.82.0-2.40.9-2.5-2.4-2.4
Bone: periosteal estimation1.42.84.31.01.5-1.91.3-2.0-2.1-1.7
Bone: periosteal perimeter2.44.07.31.21.5-2.5-0.1-2.5-2.2-2.7
Bone: post-yield work0.10.10.6-0.2-0.10.10.80.2-0.00.4
Bone: stiffness0.40.71.2-0.70.0-1.10.6-0.9-1.1-0.9
Bone: tissue strength1.00.92.00.60.9-0.91.4-0.9-1.2-0.5
Bone: trabecular number0.00.00.10.30.3-0.10.3-0.1-0.1-0.1
Bone: trabecular spacing0.60.84.50.30.30.12.10.0-0.50.9
Bone: trabecular thickness0.81.02.60.40.4-1.0-1.3-1.0-0.5-1.6
Bone: trabecular tissue density0.91.31.7-1.2-1.31.2-0.71.21.21.1
Breakpoint value in progressive ratio session0.40.41.1-0.4-0.1-0.6-1.0-0.7-0.4-0.8
Distance traveled before self-admin1.21.32.31.00.8-1.3-0.7-1.4-1.0-1.5
Distance traveled after self-admin0.91.02.11.51.4-0.61.0-0.8-0.9-0.3
Delta time in closed arm before/after self-admin0.10.10.50.1-0.20.30.30.40.20.7
Delta time in open arm before/after self-admin0.00.00.0-0.10.10.2-0.10.10.0-0.0
Diff in mean of infusions in LGA sessions0.80.92.3-1.0-1.10.7-1.50.50.70.6
Extinction: sum of active levers before priming2.52.54.8-2.2-1.71.5-1.91.31.60.5
Active lever presses in extinction session 61.21.22.7-1.6-1.30.6-1.60.50.90.0
Delta distance traveled before/after self-admin0.50.51.4-0.0-0.00.80.90.70.41.2
Delta ambulatory time before/after self-admin1.11.22.9-0.4-0.51.30.71.31.01.7
Time in closed arm before self-admin0.20.20.8-0.5-0.4-0.1-0.9-0.10.2-0.5
Time in closed arm after self-admin0.60.72.5-0.7-1.00.2-1.60.40.80.1
Time in open arm before self-admin0.30.30.6-0.3-0.30.70.50.60.40.7
Time in open arm after self-admin0.20.20.5-0.5-0.20.70.40.60.40.5
Sum of active levers in priming session hrs 5-60.70.71.50.10.7-1.0-0.4-1.0-0.8-1.2
Time to tail flick, vehicle, before self-admin0.20.20.60.20.8-0.10.6-0.2-0.3-0.4
Time to tail flick, vehicle, after self-admin2.62.83.9-1.8-2.01.7-1.01.81.71.5
Time to tail flick, test, before self-admin0.20.20.40.60.4-0.60.5-0.5-0.4-0.1
Time to tail flick, test, after self-admin0.50.50.7-0.7-0.80.7-0.30.70.80.7
Delta time to tail flick, vehicle, before/after SA0.60.51.1-0.4-1.00.7-0.00.80.61.0
Delta time to tail flick, test, before/after SA1.21.12.3-1.5-1.10.9-1.20.81.00.2
Ambulatory time before self-admin2.02.13.61.11.2-1.6-0.3-1.8-1.5-1.9
Ambulatory time after self-admin0.40.51.01.00.9-0.40.7-0.6-0.6-0.4
Total heroin consumption0.81.03.7-1.4-0.9-0.1-1.9-0.10.3-0.6
Area under the delay curve1.61.72.2-1.4-1.51.3-0.41.41.41.4
Delay disc. indifference point, 0s delay0.20.20.6-0.8-0.50.3-0.20.30.30.4
Delay disc. indifference point, 16s delay2.12.14.1-1.3-1.31.60.51.71.42.0
Delay disc. indifference point, 2s delay0.40.40.6-0.8-0.70.6-0.30.60.70.5
Delay disc. indifference point, 24s delay4.64.46.3-2.2-2.32.2-1.42.32.51.6
Delay disc. indifference point, 4s delay0.70.71.7-1.3-1.00.6-0.60.60.70.7
Delay disc. indifference point, 8s delay0.70.71.3-1.0-1.20.6-0.80.81.00.6
Delay discount exponential model param2.22.33.11.71.7-1.40.8-1.6-1.7-1.4
Delay discount hyperbolic model param2.12.23.01.71.7-1.40.8-1.6-1.6-1.4
Fecal boli incidents, locomotor time 10.40.40.9-0.3-0.50.90.10.90.80.7
Change in fecal boli incidents, locomotor task1.81.74.0-1.5-1.31.0-2.00.91.40.5
Time >=10cm from walls, locomotor time 11.31.33.11.51.4-0.71.8-0.6-1.0-0.1
Bouts of movement, locomotor time 11.92.13.1-1.8-1.71.5-1.11.51.50.9
Total resting periods, locomotor time 12.12.43.3-1.8-1.81.6-1.31.51.70.9
Rest time, locomotor task time 10.20.20.5-0.4-0.50.4-0.70.30.5-0.2
Distance moved, locomotor task time 10.30.40.60.70.4-0.60.6-0.6-0.80.2
Vertical activity count, locomotor time 10.60.61.20.80.6-0.71.1-0.8-1.10.1
Time >=10cm from walls, locomotor time 20.10.10.50.10.6-0.20.7-0.1-0.3-0.1
Bouts of movement, locomotor time 21.31.42.1-1.1-1.41.2-0.61.21.11.4
Total resting periods, locomotor time 20.91.02.0-0.8-1.21.0-0.21.10.91.4
Rest time, locomotor task time 20.10.10.20.2-0.40.3-0.40.20.20.3
Distance moved, locomotor task time 20.10.10.3-0.6-0.2-0.10.00.0-0.10.4
Vertical activity count, locomotor time 20.10.20.7-0.40.0-0.00.80.1-0.20.4
Weight adjusted by age2.02.34.01.31.5-1.60.0-1.7-1.6-2.0
Seeking ratio, delayed vs. immediate footshock1.51.72.21.31.3-1.50.9-1.4-1.5-1.1
Locomotion in novel chamber0.20.30.6-0.3-0.50.60.10.70.50.8
Locomotion in novel chamber post-restriction3.44.16.42.52.2-2.11.3-2.0-2.0-1.7
Progressive ratio0.40.50.7-0.7-0.60.8-0.40.80.80.6
Food seeking constrained by brief footshock0.10.20.8-0.1-0.10.2-0.90.20.5-0.0
Seeking ratio, punishment vs. effort0.20.30.40.60.6-0.50.5-0.5-0.5-0.3
Run reversals in cocaine runway, females0.40.40.7-0.6-0.20.80.70.80.50.8
Run reversals in cocaine runway, males1.51.42.81.01.0-1.3-0.4-1.4-1.1-1.7
Latency to leave start box in cocaine runway0.20.30.6-0.1-0.50.70.00.60.40.8
Latency to leave start box in cocaine runway, F0.50.51.1-0.4-0.41.00.50.80.51.0
Latency to leave start box in cocaine runway, M0.20.20.80.90.2-0.5-0.2-0.4-0.3-0.2
Cd content in liver1.61.82.4-1.5-1.31.4-0.41.51.41.4
Co content in liver0.20.20.5-0.3-0.10.70.10.50.50.5
Cu content in liver0.30.40.90.40.2-0.6-0.9-0.7-0.2-0.9
Fe content in liver0.91.11.7-0.8-0.81.3-0.31.21.21.3
K content in liver2.32.33.91.81.8-1.12.0-1.3-1.5-0.7
Mg content in liver1.01.04.61.01.00.02.1-0.1-0.50.6
Mn content in liver0.20.20.40.30.4-0.60.2-0.6-0.6-0.6
Na content in liver0.00.00.00.1-0.20.1-0.10.00.10.1
Rb content in liver1.11.32.81.01.2-1.01.7-0.9-1.3-0.6
Se content in liver0.60.71.71.31.0-0.60.7-0.7-0.7-0.4
Sr content in liver0.60.63.3-0.0-0.2-0.2-1.8-0.00.4-0.6
Zn content in liver0.00.00.10.30.10.10.10.10.20.1