Hub : Genes

Slc39a3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000045524 0.17 0.11 0.0e+00 0.16 0.16 0.16 0.16 6.7e-17 2.5e-17 5.2e-17 5.6e-17
2 Adipose mRNA stability ENSRNOG00000045524 0.07 0.06 7.6e-08 0.06 0.05 0.05 0.05 1.7e-07 3.0e-06 4.8e-06 1.8e-06
3 BLA gene expression ENSRNOG00000045524 0.13 0.08 1.4e-08 0.15 0.15 0.13 0.16 2.0e-08 2.0e-08 1.3e-07 1.1e-08
4 BLA mRNA stability ENSRNOG00000045524 0.09 0.07 4.7e-05 0.07 0.06 0.04 0.06 1.3e-04 5.9e-04 2.9e-03 4.5e-04
5 Brain gene expression ENSRNOG00000045524 0.37 0.24 0.0e+00 0.24 0.23 0.23 0.24 2.9e-22 1.6e-21 1.6e-21 8.7e-22
6 Brain mRNA stability ENSRNOG00000045524 0.04 0.03 1.2e-04 0.03 0.03 0.02 0.02 2.2e-03 1.9e-03 2.5e-03 5.9e-03
7 Eye gene expression ENSRNOG00000045524 0.49 0.22 4.4e-03 0.01 0.16 0.16 0.11 2.5e-01 2.0e-03 2.1e-03 8.2e-03
8 Liver gene expression ENSRNOG00000045524 0.26 0.16 0.0e+00 0.23 0.22 0.22 0.22 2.9e-25 2.0e-23 2.4e-24 2.3e-24
9 Liver mRNA stability ENSRNOG00000045524 0.02 0.02 2.9e-03 0.02 0.02 0.02 0.02 2.4e-03 3.7e-03 5.9e-03 5.1e-03
10 NAcc gene expression ENSRNOG00000045524 0.08 0.06 5.7e-08 0.08 0.09 0.08 0.09 1.3e-06 1.7e-07 7.9e-07 4.9e-07
11 NAcc mRNA stability ENSRNOG00000045524 0.07 0.05 5.5e-06 0.05 0.07 0.07 0.06 9.0e-05 1.1e-05 1.1e-05 2.3e-05
12 OFC gene expression ENSRNOG00000045524 0.13 0.1 1.4e-03 0.15 0.09 0.12 0.12 2.1e-04 3.8e-03 1.1e-03 8.4e-04
13 PL gene expression ENSRNOG00000045524 0.14 0.09 1.1e-11 0.15 0.15 0.14 0.15 2.8e-11 2.9e-11 5.4e-11 2.1e-11
14 PL mRNA stability ENSRNOG00000045524 0.06 0.05 4.0e-05 0.05 0.04 0.04 0.04 9.0e-05 3.1e-04 5.2e-04 3.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail6.220.123.0-4.7-4.6-4.5-4.6-4.6-4.7-2.4-4.5-4.5-4.7-4.8-4.5-4.5-4.6
BMI without tail1.83.85.7-2.1-2.0-1.9-2.0-2.0-2.2-0.4-1.9-1.9-2.2-2.4-1.9-1.8-2.0
Body weight1.14.55.2-2.2-2.2-2.1-2.1-2.1-2.2-1.1-2.1-2.1-2.3-2.3-2.1-2.1-2.2
Epididymis fat weight0.20.61.10.70.80.80.80.80.61.10.70.70.60.50.70.80.8
Glucose1.11.72.1-1.4-1.3-1.4-1.3-1.3-1.4-0.7-1.3-1.3-1.4-1.5-1.3-1.2-1.3
Heart weight0.50.71.30.80.80.90.90.90.71.10.80.80.70.50.90.90.9
Left kidney weight0.00.10.40.20.00.10.10.10.2-0.60.10.10.30.40.10.00.0
Right kidney weight1.33.84.52.12.02.02.02.02.11.02.02.02.12.12.01.91.9
Tail length3.410.411.23.23.33.23.33.33.22.53.33.33.23.13.33.33.3
Length with tail1.86.67.92.72.62.62.72.72.71.22.62.62.82.82.62.62.6
Length without tail0.00.11.00.2-0.00.10.10.10.2-1.00.00.00.30.5-0.0-0.10.0
Liver weight, left2.23.54.8-2.0-1.9-1.9-1.8-1.8-2.1-0.7-1.9-1.9-2.1-2.2-1.9-1.7-1.8
Liver weight, right1.82.93.2-1.8-1.8-1.8-1.7-1.7-1.8-1.2-1.8-1.8-1.8-1.8-1.8-1.7-1.7
Parametrial fat weight0.51.01.21.01.00.91.11.11.00.91.11.11.00.91.11.11.1
Retroperitoneal fat weight0.31.01.4-1.1-1.0-0.9-1.1-1.1-1.1-0.2-1.0-1.0-1.1-1.2-1.0-1.0-1.1
Intraocular pressure0.20.32.40.30.40.50.50.50.21.60.50.50.1-0.10.50.60.5
Extensor digitorum longus weight3.815.320.7-4.2-3.9-4.1-3.9-3.9-4.3-1.4-3.9-3.9-4.4-4.6-3.9-3.7-3.9
Soleus weight8.926.028.5-5.3-5.2-5.2-5.1-5.1-5.3-3.2-5.2-5.2-5.3-5.3-5.3-5.1-5.2
Tibialis anterior weight1.03.54.6-2.0-1.9-2.1-1.8-1.8-2.0-1.3-1.9-1.9-2.0-2.0-1.8-1.8-1.8
Tibia length1.02.83.11.71.71.71.81.81.71.21.71.71.71.61.71.71.8
Number of licking bursts0.10.11.10.00.20.20.00.0-0.01.00.20.2-0.1-0.30.20.10.0
Food consumed during 24 hour testing period0.40.50.6-0.8-0.7-0.7-0.8-0.8-0.8-0.4-0.7-0.7-0.8-0.8-0.7-0.7-0.8
Times rat made contact with spout0.10.10.3-0.4-0.3-0.3-0.3-0.3-0.40.4-0.3-0.3-0.4-0.6-0.3-0.2-0.3
Mean time between licks in bursts4.56.36.62.52.62.62.52.52.52.12.62.62.52.42.62.62.5
Mean num. licks in bursts0.10.10.3-0.2-0.3-0.3-0.2-0.2-0.2-0.6-0.3-0.3-0.2-0.1-0.3-0.2-0.2
Std. dev. time between licks in bursts0.50.71.30.90.80.80.70.71.0-0.30.80.81.01.20.80.60.7
Water consumed over 24 hours0.81.02.0-0.9-1.0-1.0-1.0-1.0-0.8-1.4-1.0-1.0-0.8-0.6-1.0-1.1-1.0
Indifference point 0 sec0.20.30.4-0.5-0.5-0.5-0.6-0.6-0.5-0.6-0.6-0.6-0.5-0.4-0.6-0.6-0.6
Indifference point AUC1.11.31.61.21.21.11.21.21.11.01.21.21.11.01.31.21.2
Indifference point function ln k0.20.30.4-0.6-0.5-0.6-0.6-0.6-0.6-0.4-0.6-0.6-0.6-0.6-0.7-0.5-0.6
Indifference point function log k0.20.30.4-0.6-0.5-0.6-0.6-0.6-0.6-0.4-0.6-0.6-0.6-0.6-0.7-0.5-0.6
Delay discounting total patch changes 0 sec0.10.20.3-0.4-0.4-0.4-0.5-0.5-0.4-0.4-0.5-0.5-0.4-0.4-0.5-0.5-0.5
Delay discounting total patch changes 12 sec0.20.20.6-0.5-0.4-0.3-0.5-0.5-0.60.5-0.4-0.4-0.6-0.8-0.4-0.4-0.5
Delay discounting total patch changes 18 sec1.11.41.71.21.21.31.21.21.20.91.21.21.21.21.21.21.2
Delay discounting total patch changes 24 sec0.10.10.10.30.30.30.20.20.30.20.30.30.30.30.30.20.2
Delay discounting total patch changes 6 sec0.20.20.40.50.60.60.40.40.60.30.50.50.60.60.40.40.4
Delay discounting time to switch 0 sec2.13.24.1-1.7-1.9-1.6-1.9-1.9-1.6-2.0-1.9-1.9-1.6-1.4-1.8-1.9-1.9
Delay discounting water rate 0 sec0.20.32.00.40.70.30.50.50.31.40.60.60.20.00.50.60.5
Delay discounting water rate 12 sec0.50.81.8-1.0-0.7-0.8-0.8-0.8-1.00.7-0.7-0.7-1.1-1.4-0.7-0.7-0.8
Delay discounting water rate 18 sec0.81.06.30.61.00.80.80.80.52.50.90.90.4-0.00.81.00.8
Delay discounting water rate 24 sec0.30.44.1-0.30.2-0.10.10.1-0.42.00.10.1-0.5-0.90.00.20.1
Delay discounting water rate 6 sec0.81.23.80.91.11.01.11.10.81.91.11.10.70.51.11.21.1
Locomotor activity2.74.36.72.32.12.02.02.02.30.32.12.12.42.62.11.92.0
Locomotor testing distance1.72.84.11.81.71.71.61.61.90.51.71.71.92.01.71.61.7
Locomotor testing rearing0.10.10.30.30.30.40.30.30.20.50.30.30.20.20.30.30.3
Light reinforcement 15.39.711.33.33.13.23.13.13.31.73.23.23.33.43.33.03.1
Light reinforcement 21.72.22.81.61.51.61.51.51.60.71.51.51.61.71.51.41.5
Reaction time number correct0.30.41.0-0.7-0.5-0.6-0.6-0.6-0.80.7-0.5-0.5-0.8-1.0-0.6-0.5-0.6
Reaction time mean minus median0.81.01.21.11.11.01.01.01.10.61.11.11.11.11.01.01.0
Reaction time mean minus median AUC0.10.11.4-0.0-0.2-0.2-0.2-0.20.0-1.2-0.1-0.10.10.3-0.1-0.3-0.1
Reaction time num false alarms0.00.00.1-0.1-0.0-0.1-0.1-0.1-0.20.4-0.0-0.0-0.2-0.3-0.0-0.0-0.1
Reaction time num false alarms AUC0.00.10.4-0.2-0.1-0.2-0.1-0.1-0.20.6-0.1-0.1-0.3-0.4-0.00.0-0.1
Reaction time trials correct on left0.30.41.0-0.7-0.5-0.6-0.6-0.6-0.80.7-0.5-0.5-0.8-1.0-0.6-0.5-0.6
Reaction time trials on left0.30.41.0-0.7-0.5-0.7-0.6-0.6-0.80.6-0.6-0.6-0.8-1.0-0.6-0.5-0.6
Reaction time mean0.10.10.8-0.1-0.2-0.1-0.3-0.3-0.1-0.9-0.2-0.2-0.00.1-0.3-0.3-0.3
Reaction time mean AUC0.10.10.9-0.2-0.3-0.2-0.4-0.4-0.1-1.0-0.3-0.3-0.10.1-0.4-0.4-0.4
Median of all reaction times0.50.61.5-0.6-0.7-0.6-0.8-0.8-0.6-1.2-0.8-0.8-0.6-0.4-0.8-0.9-0.8
Reaction time omissions0.20.30.50.60.60.40.50.50.60.10.60.60.60.70.50.50.5
Reaction time false alarm rate0.00.00.0-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.1-0.1
Reaction time premature initiation rate1.31.72.21.31.41.51.31.31.21.51.31.31.21.11.31.31.3
Reaction time premature initiations0.91.33.71.01.31.21.11.10.91.91.21.20.90.61.11.21.1
Std. dev. reaction times0.20.30.50.60.50.50.40.40.6-0.10.50.50.60.70.40.40.5
Reaction time trials completed0.30.41.0-0.7-0.5-0.7-0.6-0.6-0.80.6-0.6-0.6-0.8-1.0-0.6-0.5-0.6
Reaction time trials AUC0.30.41.0-0.6-0.4-0.6-0.5-0.5-0.70.8-0.4-0.4-0.8-1.0-0.5-0.4-0.5
Social response proportion0.40.50.70.70.60.80.70.70.70.10.60.60.80.80.60.70.7
Social responses6.38.210.63.02.82.83.03.03.11.02.82.83.13.32.82.83.0
Social time0.60.70.9-0.9-0.9-0.8-0.9-0.9-0.9-0.3-0.9-0.9-0.9-1.0-0.9-0.9-0.9
Conditioned locomotion1.11.32.4-1.2-1.1-1.0-1.1-1.1-1.30.4-1.1-1.1-1.4-1.6-1.1-1.0-1.1
Cocaine response after cond. corrected3.94.46.8-2.3-2.0-2.1-2.1-2.1-2.3-0.2-2.0-2.0-2.4-2.6-2.1-2.0-2.1
Cocaine response after cond. not corrected4.24.67.2-2.3-2.1-2.1-2.2-2.2-2.4-0.1-2.1-2.1-2.5-2.7-2.2-2.0-2.1
Cocaine response before conditioning0.30.40.70.70.60.70.70.70.70.10.60.60.80.80.60.60.7
Saline control response0.00.00.1-0.2-0.2-0.1-0.2-0.2-0.20.2-0.2-0.2-0.2-0.3-0.2-0.1-0.2
Condit. Reinf. active minus inactive responses2.93.63.91.81.91.91.91.91.81.91.91.91.81.62.02.01.9
Condit. Reinf. active-inactive response ratio0.50.52.40.50.70.70.70.70.41.50.70.70.30.10.70.80.7
Condit. Reinf. active responses2.43.33.61.91.91.81.81.81.91.31.91.91.91.81.91.81.8
Condit. Reinf. inactive responses1.01.21.91.21.11.11.01.01.20.21.11.11.31.41.11.01.0
Condit. Reinf. lever presses2.73.84.11.92.02.02.02.01.91.82.02.01.91.72.02.02.0
Condit. Reinf. lever reinforcers received1.92.72.91.71.71.71.71.71.71.41.71.71.61.61.71.71.7
Pavlov. Cond. lever latency0.81.11.3-1.1-1.0-1.1-1.1-1.1-1.1-0.5-1.1-1.1-1.1-1.2-1.1-1.1-1.1
Pavlov. Cond. magazine entry latency0.50.50.70.80.70.70.80.80.80.10.70.70.80.90.80.70.8
Pavlov. Cond. change in total contacts0.91.31.51.11.11.11.21.21.10.71.11.11.11.11.21.21.2
Pavlov. Cond. index score1.01.31.51.21.11.11.21.21.20.61.11.11.21.21.21.21.2
Pavlov. Cond. latency score0.81.11.31.11.01.01.11.11.10.41.01.01.11.21.11.01.1
Pavlov. Cond. lever contacts0.91.21.41.11.11.11.21.21.10.91.11.11.11.11.11.21.2
Pavlov. Cond. magazine entry number0.81.01.2-1.0-1.0-0.9-1.0-1.0-1.0-0.2-1.0-1.0-1.1-1.1-1.0-1.0-1.0
Pavlov. Cond. intertrial magazine entries0.30.30.6-0.6-0.4-0.4-0.7-0.7-0.60.3-0.5-0.5-0.6-0.7-0.4-0.6-0.7
Pavlov. Cond. lever-magazine prob. diff.0.91.21.41.11.11.11.21.21.20.51.11.11.21.21.11.11.2
Pavlov. Cond. response bias2.12.93.21.71.71.71.81.81.71.31.71.71.71.61.71.81.8
Conditioned reinforcement - actives2.62.52.91.71.71.31.61.61.71.01.71.71.71.71.61.61.7
Conditioned reinforcement - inactives0.40.40.8-0.7-0.6-0.8-0.6-0.6-0.70.2-0.6-0.6-0.8-0.9-0.6-0.6-0.6
Conditioned locomotion8.19.710.73.23.22.83.23.23.22.03.23.23.23.23.33.23.2
Intermittent access intake day 1-15 change7.57.58.12.82.82.72.82.82.82.12.82.82.82.72.82.82.8
Intermittent access intake escalation8.18.08.72.82.92.72.92.92.72.82.92.92.72.52.92.93.0
Intermittent access intake escalation 29.79.710.43.13.23.13.23.23.03.03.23.23.02.73.23.23.2
Intermitt. access day 1 inactive lever presses0.60.71.20.70.90.50.90.90.71.10.90.90.60.51.01.00.9
Intermitt. access day 15 inactive lever presses0.60.61.00.80.80.80.70.70.80.80.80.80.70.71.00.80.8
Intermitt. access escalation Index0.60.51.7-0.5-0.7-0.6-0.8-0.8-0.5-1.3-0.7-0.7-0.4-0.2-0.7-0.8-0.7
Intermittent access day 1 total infusions0.10.10.2-0.3-0.3-0.4-0.4-0.4-0.2-0.3-0.3-0.3-0.2-0.2-0.1-0.4-0.2
Intermittent access day 15 total infusions2.32.53.11.61.71.51.51.51.61.51.71.71.61.51.81.51.7
Intermittent access terminal intake (last 3 days)1.21.31.71.21.21.01.01.01.20.91.21.21.21.21.31.11.3
Intermittent access total infusions0.20.30.40.50.60.40.40.40.50.60.60.60.50.50.60.40.6
Intermittent access day 1 locomotion0.40.40.50.60.60.60.50.50.60.60.60.60.60.60.60.50.7
Intermittent access day 15 total locomotion4.04.24.92.12.21.92.02.02.11.62.22.22.12.02.22.02.2
Intermittent access total locomotion1.11.21.51.21.20.81.01.01.20.71.21.21.21.21.21.01.2
Intermittent access standard deviation3.73.94.62.02.11.72.02.02.01.72.12.11.91.82.12.02.1
Cocaine induced anxiety0.40.51.00.80.60.40.70.70.8-0.40.60.60.91.00.60.60.6
Post-drug Anxiety0.20.20.60.50.30.50.40.40.5-0.80.30.30.60.80.30.30.3
Baseline Anxiety0.10.10.50.20.30.60.20.20.20.70.30.30.20.10.30.20.2
Lifetime Intake0.10.10.10.30.30.10.10.10.30.30.30.30.30.30.40.10.4
Incentive Sensitization - Responses0.50.50.90.70.80.40.70.70.60.90.80.80.60.50.70.80.8
Incentive Sensitization - Breakpoint0.50.50.70.70.80.50.80.80.60.80.80.80.60.50.70.80.8
Progressive ratio test 1 active lever presses0.10.10.1-0.3-0.2-0.3-0.3-0.3-0.30.2-0.2-0.2-0.3-0.4-0.2-0.3-0.2
Progressive ratio test 1 breakpoint0.10.10.2-0.4-0.3-0.4-0.5-0.5-0.40.1-0.3-0.3-0.4-0.5-0.4-0.4-0.3
Progressive ratio test 1 inactive lever presses0.00.00.10.10.1-0.10.00.00.1-0.00.10.10.10.10.20.00.1
Progressive ratio test 2 active lever presses0.30.40.70.60.70.40.60.60.50.80.70.70.50.40.60.60.7
Progressive ratio test 2 breakpoint0.30.40.50.60.70.40.60.60.60.50.70.70.60.60.60.60.7
Progressive ratio test 2 inactive lever presses0.00.00.10.30.2-0.00.10.10.30.00.20.20.30.30.30.10.3
Total sessions with >9 infusions0.00.10.30.0-0.1-0.4-0.2-0.20.0-0.6-0.1-0.10.00.2-0.1-0.2-0.1
Short access day 1 total inactive lever presses0.00.00.00.20.2-0.00.20.20.20.20.20.20.20.20.20.20.2
Short access day 10 total inactive lever presses0.20.20.50.30.40.10.40.40.30.70.40.40.20.10.60.40.4
Short access day 1 total infusions0.10.10.20.30.1-0.0-0.0-0.00.3-0.50.10.10.30.50.2-0.10.2
Short access day 10 total infusions0.00.00.10.20.2-0.0-0.1-0.10.10.30.20.20.10.10.3-0.00.2
Short access total infusions0.00.00.10.0-0.0-0.2-0.2-0.20.0-0.2-0.0-0.00.00.1-0.0-0.20.0
Short access day 1 locomotion0.70.71.41.00.90.60.70.71.00.00.90.91.11.21.00.60.9
Short access day 10 total locomotion4.85.25.82.32.42.02.32.32.31.92.42.42.32.22.32.32.4
Short access total locomotion0.90.91.31.11.00.60.80.81.10.51.01.01.11.11.00.81.1
Compulsive drug intake1.31.31.7-1.1-1.2-1.3-0.9-0.9-1.1-1.1-1.2-1.2-1.1-1.0-1.3-1.0-1.2
One hour access (0.3 mA shock)0.20.20.4-0.4-0.4-0.6-0.5-0.5-0.4-0.2-0.4-0.4-0.4-0.4-0.4-0.5-0.4
One hour access (shock baseline)0.10.10.50.30.40.20.20.20.30.70.40.40.30.20.40.30.4
Number of responses in last shaping day0.20.20.20.50.40.10.30.30.50.20.40.40.50.50.50.30.4
Context. condit. distance diff. score0.30.30.4-0.6-0.5-0.6-0.6-0.6-0.6-0.2-0.5-0.5-0.6-0.6-0.5-0.5-0.6
Locomotion velocity, session 10.30.40.80.60.50.50.60.60.7-0.60.50.50.70.90.50.40.6
Locomotion distance, session 10.10.21.80.1-0.1-0.2-0.1-0.10.1-1.3-0.1-0.10.20.5-0.1-0.3-0.1
Locomotion velocity, session 22.32.74.81.81.61.71.61.61.9-0.31.51.52.02.21.61.41.6
Locomotion distance, session 20.81.12.61.21.01.00.90.91.3-0.80.90.91.41.61.00.70.9
Locomotion velocity, session 36.27.27.62.82.72.72.82.82.81.82.72.72.82.72.72.72.8
Locomotion distance, session 30.00.00.00.00.1-0.10.20.20.00.20.10.10.0-0.00.10.20.2
Stereotopy head waving bouts, day 34.14.96.22.32.22.32.22.22.40.92.22.22.42.52.22.22.2
Stereotopy head waving duration, day 35.16.27.22.62.52.62.52.52.61.32.52.52.62.72.52.42.5
Locomotion velocity, session 70.60.71.00.90.80.80.80.80.90.20.80.80.91.00.80.80.8
Locomotion distance, session 70.00.00.3-0.2-0.1-0.1-0.0-0.0-0.20.5-0.0-0.0-0.2-0.4-0.10.0-0.0
Stereotopy head waving bouts, day 70.10.11.3-0.1-0.3-0.2-0.2-0.2-0.1-1.2-0.3-0.30.00.2-0.3-0.3-0.2
Stereotopy head waving duration, day 70.10.11.10.30.10.10.10.10.3-1.00.10.10.40.60.1-0.00.1
Locomotion velocity, session 80.20.31.40.50.30.40.30.30.6-1.20.20.20.70.90.30.10.3
Locomotion distance, session 80.00.10.20.30.20.20.10.10.3-0.30.20.20.30.40.20.10.1
Degree of sensitization distance0.40.40.5-0.6-0.6-0.6-0.7-0.7-0.6-0.4-0.6-0.6-0.6-0.6-0.6-0.7-0.7
Degree of sensitization stereotypy2.32.53.3-1.5-1.6-1.6-1.6-1.6-1.5-1.8-1.6-1.6-1.4-1.3-1.6-1.7-1.6
Condit. Reinf. active minus inactive responses4.04.55.02.22.22.12.12.12.21.22.22.22.22.22.22.12.1
Condit. Reinf. active-inactive response ratio2.52.72.91.61.71.71.71.71.61.51.71.71.61.51.71.71.7
Condit. Reinf. active responses2.93.65.02.01.91.91.91.92.10.51.91.92.12.21.91.81.9
Condit. Reinf. inactive responses0.40.51.20.80.70.60.60.60.9-0.50.60.60.91.10.70.50.6
Incentive salience index mean1.72.13.11.61.51.41.41.41.60.31.41.41.61.71.51.41.4
Condit. Reinf. lever presses0.20.22.5-0.1-0.2-0.4-0.3-0.3-0.0-1.6-0.3-0.30.10.3-0.2-0.4-0.3
Time in familiar zone, hab. session 12.42.22.91.51.51.71.51.51.51.31.51.51.51.41.51.61.5
Time in novel zone, hab. session 11.41.42.5-1.1-1.1-1.3-1.2-1.2-1.0-1.6-1.2-1.2-1.0-0.8-1.1-1.3-1.2
Total zone transitions, hab. session 10.50.71.50.90.80.80.70.71.0-0.60.70.71.01.20.80.60.7
Total locomotion distance, hab. session 10.50.72.00.90.60.70.60.61.0-1.30.60.61.11.40.60.50.6
Locomotion velocity, hab. session 10.81.22.61.21.01.01.01.01.3-0.70.90.91.41.61.00.81.0
Time in familiar zone, hab. session 27.17.48.12.72.72.82.82.82.72.52.82.82.62.52.72.92.8
Time in novel zone, hab. session 25.55.56.1-2.3-2.4-2.4-2.4-2.4-2.3-2.3-2.4-2.4-2.2-2.0-2.4-2.5-2.4
Total zone transitions, hab. session 20.60.83.2-0.6-0.8-0.8-0.9-0.9-0.6-1.8-0.9-0.9-0.5-0.2-0.8-1.0-0.9
Total locomotion distance, hab. session 20.40.61.30.90.70.80.70.70.9-0.50.60.61.01.10.70.50.7
Locomotion velocity, hab. session 20.40.51.30.80.60.70.60.60.8-0.80.50.50.91.10.60.40.6
Novel to familiar place preference ratio4.75.06.2-2.2-2.3-2.4-2.2-2.2-2.1-2.5-2.3-2.3-2.1-1.8-2.3-2.3-2.2
Novelty place preference3.03.14.5-1.7-1.8-1.9-1.7-1.7-1.6-2.1-1.8-1.8-1.6-1.4-1.8-1.8-1.7
Time in novel zone, NPP test3.33.44.5-1.8-1.9-2.0-1.8-1.8-1.8-2.1-1.9-1.9-1.7-1.5-1.9-1.9-1.8
Total zone transitions, NPP test0.10.10.7-0.2-0.3-0.3-0.4-0.4-0.2-0.8-0.3-0.3-0.1-0.0-0.3-0.4-0.4
Total locomotion distance, NPP test0.20.31.5-0.3-0.5-0.4-0.5-0.5-0.3-1.2-0.5-0.5-0.2-0.0-0.5-0.6-0.5
Locomotion velocity, NPP test0.10.11.0-0.0-0.2-0.1-0.2-0.20.0-1.0-0.2-0.20.10.3-0.2-0.3-0.2
Pavlov. Cond. lever latency0.10.21.30.20.40.30.30.30.21.10.40.40.1-0.10.40.40.3
Pavlov. Cond. magazine entry latency2.93.74.22.02.02.01.91.92.01.52.02.02.01.92.01.91.9
Pavlov. Cond. change in total contacts0.00.00.10.20.20.20.20.20.20.00.20.20.20.20.20.20.2
Pavlov. Cond. index score0.20.30.60.60.50.60.50.50.6-0.20.50.50.70.80.50.40.5
Pavlov. Cond. latency score0.20.20.60.50.40.40.40.40.6-0.60.40.40.60.80.40.30.4
Pavlov. Cond. lever contacts0.10.11.5-0.0-0.2-0.2-0.1-0.10.0-1.2-0.2-0.20.10.3-0.2-0.2-0.1
Pavlov. Cond. magazine entry number0.60.70.9-0.9-0.9-1.0-0.8-0.8-0.9-0.5-0.9-0.9-0.9-0.9-0.9-0.8-0.8
Pavlov. Cond. intertrial magazine entries0.20.31.10.40.60.60.40.40.41.10.50.50.40.20.60.50.4
Pavlov. Cond. lever-magazine prob. diff.0.50.61.10.90.80.90.80.80.9-0.00.80.80.91.00.80.70.8
Pavlov. Cond. response bias1.01.21.41.11.11.21.11.11.10.61.11.11.21.21.11.11.1
Bone: apparent density0.40.75.1-0.3-0.6-0.7-0.6-0.6-0.2-2.3-0.6-0.6-0.10.3-0.7-0.7-0.6
Bone surface0.40.88.40.2-0.3-0.4-0.3-0.30.3-2.9-0.3-0.30.51.0-0.4-0.6-0.3
Bone volume0.50.88.30.2-0.3-0.4-0.3-0.30.3-2.9-0.3-0.30.51.0-0.4-0.6-0.3
Bone: connectivity density0.61.04.1-0.7-1.0-1.0-0.9-0.9-0.6-2.0-0.9-0.9-0.5-0.3-1.1-1.0-0.9
Bone: cortical apparent density0.81.11.4-1.0-1.0-1.0-1.2-1.2-1.1-0.6-1.0-1.0-1.1-1.1-1.1-1.1-1.2
Bone: cortical area0.91.33.1-1.0-1.1-1.2-1.2-1.2-0.9-1.8-1.1-1.1-0.9-0.6-1.1-1.3-1.2
Bone: cortical porosity0.40.40.80.70.60.60.70.70.7-0.10.60.60.80.90.60.60.6
Bone: cortical porosity0.10.10.90.0-0.1-0.1-0.1-0.10.1-0.9-0.1-0.10.10.3-0.1-0.2-0.1
Bone: cortical thickness1.32.22.5-1.4-1.5-1.5-1.6-1.6-1.4-1.4-1.5-1.5-1.4-1.3-1.4-1.6-1.6
Bone: cortical thickness0.10.10.60.20.30.30.20.20.10.80.30.30.1-0.00.30.30.2
Bone: cortical tissue density0.60.70.9-0.9-0.8-0.8-1.0-1.0-0.9-0.4-0.8-0.8-0.9-0.9-0.9-0.9-0.9
Bone: elastic displacement0.30.30.40.50.50.50.60.60.60.20.50.50.60.60.50.60.6
Bone: elastic work0.30.30.7-0.5-0.6-0.6-0.6-0.6-0.5-0.9-0.6-0.6-0.5-0.4-0.5-0.6-0.6
Bone: endosteal estimation0.30.61.2-0.7-0.8-0.8-0.8-0.8-0.7-1.1-0.8-0.8-0.6-0.5-0.7-0.8-0.8
Bone: endosteal perimeter0.10.30.80.60.40.50.40.40.6-0.70.40.40.70.90.50.30.4
Bone: final force1.62.63.7-1.5-1.6-1.6-1.7-1.7-1.5-1.9-1.6-1.6-1.4-1.2-1.5-1.7-1.7
Bone: final moment1.22.03.1-1.3-1.4-1.4-1.5-1.5-1.3-1.8-1.4-1.4-1.2-1.1-1.3-1.6-1.5
Bone: marrow area0.30.61.1-0.7-0.8-0.8-0.8-0.8-0.7-1.1-0.8-0.8-0.7-0.5-0.8-0.9-0.8
Bone: maximum diameter0.40.71.81.00.80.80.70.71.0-0.60.80.81.11.30.90.60.7
Bone: maximum force1.52.63.0-1.5-1.6-1.6-1.7-1.7-1.5-1.7-1.6-1.6-1.5-1.3-1.5-1.7-1.7
Bone: maximum moment1.22.12.6-1.4-1.5-1.5-1.6-1.6-1.3-1.6-1.5-1.5-1.3-1.2-1.4-1.6-1.6
Bone: minimum diameter0.10.10.9-0.1-0.3-0.3-0.3-0.3-0.1-1.0-0.3-0.3-0.10.1-0.3-0.4-0.3
Bone: periosteal estimation0.61.23.3-0.9-1.1-1.1-1.2-1.2-0.8-1.8-1.1-1.1-0.8-0.5-1.0-1.2-1.2
Bone: periosteal perimeter0.10.11.40.2-0.0-0.0-0.1-0.10.2-1.2-0.1-0.10.30.50.0-0.2-0.1
Bone: post-yield work0.60.81.0-0.9-0.8-0.8-1.0-1.0-0.9-0.5-0.9-0.9-0.9-0.9-0.8-1.0-1.0
Bone: stiffness3.45.46.1-2.3-2.3-2.3-2.4-2.4-2.3-2.0-2.4-2.4-2.3-2.1-2.3-2.4-2.5
Bone: tissue strength1.91.92.2-1.3-1.4-1.4-1.5-1.5-1.3-1.1-1.4-1.4-1.3-1.3-1.3-1.5-1.5
Bone: trabecular number0.40.51.40.80.60.50.70.70.9-0.90.60.61.01.20.40.50.7
Bone: trabecular spacing0.30.43.0-0.4-0.1-0.1-0.1-0.1-0.51.7-0.1-0.1-0.6-1.0-0.00.1-0.1
Bone: trabecular thickness0.80.98.3-0.3-0.7-0.7-0.7-0.7-0.2-2.9-0.7-0.70.00.5-0.7-0.9-0.7
Bone: trabecular tissue density1.52.13.2-1.6-1.4-1.4-1.6-1.6-1.6-0.0-1.4-1.4-1.7-1.8-1.3-1.5-1.6
Breakpoint value in progressive ratio session5.96.67.12.62.62.42.62.62.62.22.62.62.62.42.62.62.7
Distance traveled before self-admin0.30.40.8-0.6-0.5-0.9-0.5-0.5-0.6-0.7-0.5-0.5-0.6-0.5-0.6-0.6-0.6
Distance traveled after self-admin0.70.81.00.91.00.61.01.00.90.30.80.81.01.00.81.00.9
Delta time in closed arm before/after self-admin0.40.31.8-0.5-0.3-0.4-0.2-0.2-0.61.4-0.3-0.3-0.7-1.0-0.3-0.0-0.3
Delta time in open arm before/after self-admin1.41.31.5-1.2-1.2-1.0-1.2-1.2-1.2-1.1-1.2-1.2-1.1-1.1-1.2-1.2-1.2
Diff in mean of infusions in LGA sessions1.61.82.11.41.41.41.41.41.41.01.31.31.41.41.31.41.4
Extinction: sum of active levers before priming1.81.83.21.31.41.11.31.31.21.81.51.51.21.01.41.41.4
Active lever presses in extinction session 63.02.83.41.81.81.41.71.71.81.01.71.71.81.81.71.71.8
Delta distance traveled before/after self-admin1.51.62.01.31.31.41.31.31.40.71.21.21.41.41.21.31.3
Delta ambulatory time before/after self-admin1.51.62.21.41.31.41.31.31.40.51.11.11.41.51.21.21.3
Time in closed arm before self-admin1.31.42.8-1.1-1.3-1.1-1.2-1.2-1.0-1.7-1.2-1.2-1.0-0.8-1.2-1.3-1.2
Time in closed arm after self-admin0.00.00.10.10.10.10.20.20.10.20.00.00.10.00.00.20.0
Time in open arm before self-admin1.21.31.51.11.20.81.21.21.11.01.21.21.11.01.21.21.2
Time in open arm after self-admin0.60.60.8-0.9-0.8-0.8-0.8-0.8-0.9-0.4-0.7-0.7-0.9-0.9-0.7-0.8-0.8
Sum of active levers in priming session hrs 5-60.00.00.00.00.1-0.1-0.0-0.00.00.20.00.00.0-0.00.0-0.00.1
Time to tail flick, vehicle, before self-admin0.30.30.70.60.40.50.60.60.6-0.60.50.50.70.80.50.50.5
Time to tail flick, vehicle, after self-admin0.30.31.30.30.40.70.60.60.31.20.50.50.20.10.50.60.4
Time to tail flick, test, before self-admin0.10.10.50.30.00.20.00.00.3-0.70.10.10.40.50.2-0.00.1
Time to tail flick, test, after self-admin0.10.10.30.40.30.50.20.20.4-0.30.30.30.40.50.30.20.3
Delta time to tail flick, vehicle, before/after SA0.30.31.0-0.5-0.4-0.2-0.3-0.3-0.61.0-0.3-0.3-0.7-0.9-0.3-0.2-0.4
Delta time to tail flick, test, before/after SA0.30.20.80.40.50.50.50.50.30.90.50.50.30.20.50.50.5
Ambulatory time before self-admin0.30.30.7-0.5-0.4-0.8-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.4
Ambulatory time after self-admin0.40.40.60.70.80.40.70.70.70.20.60.60.70.80.60.70.7
Total heroin consumption1.92.22.61.61.51.51.41.41.60.91.61.61.61.61.61.41.5
Area under the delay curve2.42.63.2-1.6-1.6-1.8-1.6-1.6-1.6-1.5-1.6-1.6-1.6-1.5-1.6-1.6-1.6
Delay disc. indifference point, 0s delay8.79.511.0-3.0-3.1-3.3-3.0-3.0-2.9-3.3-3.2-3.2-2.9-2.6-3.2-3.1-3.1
Delay disc. indifference point, 16s delay0.20.20.2-0.4-0.4-0.4-0.5-0.5-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.5-0.4
Delay disc. indifference point, 2s delay6.47.18.3-2.7-2.7-2.9-2.7-2.7-2.7-2.4-2.8-2.8-2.6-2.4-2.8-2.7-2.7
Delay disc. indifference point, 24s delay0.50.50.7-0.8-0.8-0.6-0.8-0.8-0.8-0.4-0.7-0.7-0.8-0.8-0.7-0.7-0.7
Delay disc. indifference point, 4s delay1.51.62.6-1.2-1.3-1.4-1.3-1.3-1.2-1.6-1.3-1.3-1.1-1.0-1.2-1.3-1.3
Delay disc. indifference point, 8s delay0.90.91.3-1.1-1.0-1.1-0.9-0.9-1.1-0.4-1.0-1.0-1.1-1.2-1.0-0.8-1.0
Delay discount exponential model param2.22.32.91.51.51.71.51.51.51.31.51.51.51.41.51.51.5
Delay discount hyperbolic model param3.13.34.11.81.92.01.81.81.81.61.81.81.81.71.81.81.8
Fecal boli incidents, locomotor time 11.41.52.3-1.3-1.2-1.2-1.2-1.2-1.4-0.1-1.2-1.2-1.4-1.5-1.2-1.2-1.2
Change in fecal boli incidents, locomotor task0.20.20.50.50.30.30.40.40.5-0.70.30.30.60.70.30.30.3
Time >=10cm from walls, locomotor time 10.50.51.2-0.6-0.6-0.7-0.8-0.8-0.6-1.1-0.7-0.7-0.5-0.4-0.7-0.8-0.7
Bouts of movement, locomotor time 10.20.20.30.50.50.50.40.40.50.50.50.50.40.40.50.40.5
Total resting periods, locomotor time 10.20.20.30.50.60.50.40.40.50.30.50.50.50.50.50.40.5
Rest time, locomotor task time 10.20.20.30.40.50.40.40.40.50.10.40.40.50.50.40.40.4
Distance moved, locomotor task time 10.70.71.9-0.7-0.9-0.8-0.8-0.8-0.7-1.4-0.9-0.9-0.6-0.5-0.8-0.9-0.8
Vertical activity count, locomotor time 10.00.00.1-0.2-0.2-0.2-0.1-0.1-0.20.1-0.2-0.2-0.2-0.3-0.2-0.0-0.2
Time >=10cm from walls, locomotor time 20.80.91.3-1.0-0.8-0.9-1.0-1.0-1.0-0.2-0.9-0.9-1.1-1.1-0.9-0.9-0.9
Bouts of movement, locomotor time 20.20.20.60.50.40.40.40.40.6-0.50.40.40.60.80.40.30.4
Total resting periods, locomotor time 20.20.20.50.50.40.30.30.30.5-0.60.30.30.60.70.30.20.3
Rest time, locomotor task time 20.30.40.80.70.70.60.40.40.7-0.10.60.60.80.90.60.40.6
Distance moved, locomotor task time 20.50.61.1-0.9-0.8-0.8-0.8-0.8-0.90.0-0.8-0.8-0.9-1.0-0.8-0.7-0.8
Vertical activity count, locomotor time 20.40.41.0-0.7-0.5-0.6-0.5-0.5-0.80.5-0.6-0.6-0.9-1.0-0.6-0.4-0.6
Weight adjusted by age0.10.20.5-0.4-0.4-0.3-0.3-0.3-0.50.6-0.3-0.3-0.5-0.7-0.4-0.2-0.3
Seeking ratio, delayed vs. immediate footshock4.45.06.32.42.22.22.32.32.40.92.32.32.42.52.32.22.3
Locomotion in novel chamber0.50.71.10.70.80.60.80.80.71.10.90.90.70.50.90.90.9
Locomotion in novel chamber post-restriction0.80.91.01.01.01.00.90.91.00.70.90.91.01.01.01.00.9
Progressive ratio0.10.10.4-0.5-0.4-0.3-0.2-0.2-0.50.3-0.3-0.3-0.5-0.6-0.4-0.2-0.2
Food seeking constrained by brief footshock0.10.10.10.30.30.30.20.20.30.20.30.30.30.30.30.20.2
Seeking ratio, punishment vs. effort0.10.10.20.40.30.20.10.10.4-0.20.30.30.40.50.30.10.1
Run reversals in cocaine runway, females0.30.30.50.60.50.40.60.60.6-0.10.50.50.70.70.50.60.5
Run reversals in cocaine runway, males0.90.91.41.11.01.00.90.91.10.20.90.91.11.20.90.80.9
Latency to leave start box in cocaine runway0.70.71.61.00.90.60.60.61.0-0.50.80.81.11.30.90.60.8
Latency to leave start box in cocaine runway, F0.30.32.6-0.1-0.2-0.5-0.5-0.5-0.0-1.6-0.3-0.30.10.3-0.2-0.6-0.4
Latency to leave start box in cocaine runway, M3.83.74.31.81.91.92.02.01.82.02.02.01.71.62.02.12.0
Cd content in liver0.20.20.3-0.5-0.5-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.5
Co content in liver0.70.80.90.90.90.90.90.90.90.90.90.90.80.81.01.00.9
Cu content in liver0.20.31.4-0.4-0.5-0.6-0.5-0.5-0.3-1.2-0.5-0.5-0.3-0.1-0.5-0.6-0.5
Fe content in liver0.10.10.40.20.20.30.20.20.20.60.20.20.10.00.20.30.2
K content in liver0.10.10.9-0.1-0.2-0.3-0.2-0.2-0.1-1.0-0.2-0.2-0.00.1-0.2-0.3-0.2
Mg content in liver0.10.11.3-0.1-0.2-0.3-0.2-0.2-0.1-1.1-0.2-0.2-0.00.2-0.2-0.3-0.2
Mn content in liver0.50.62.10.80.50.50.50.50.8-1.50.50.51.01.30.50.30.5
Na content in liver1.31.42.0-1.1-1.2-1.2-1.2-1.2-1.1-1.4-1.2-1.2-1.1-0.9-1.2-1.3-1.2
Rb content in liver0.70.82.5-0.8-0.9-0.9-0.9-0.9-0.7-1.6-0.9-0.9-0.7-0.5-0.9-1.0-0.9
Se content in liver0.10.20.20.40.40.30.40.40.40.10.40.40.40.50.50.40.4
Sr content in liver0.10.11.00.10.30.30.30.30.11.00.30.30.1-0.10.30.30.3
Zn content in liver3.03.36.21.61.91.81.91.91.62.51.91.91.51.21.92.01.9