Rd3l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000043031 0.15 0.1 5.7e-08 0.15 0.15 0.14 0.14 1.2e-08 1.7e-08 4.3e-08 8.4e-08
2 BLA intron excision ratio chr6:131043426:131043787 0.04 0.03 9.6e-03 0.02 0.03 0.02 0.02 2.6e-02 8.0e-03 3.5e-02 3.3e-02
3 Brain gene expression ENSRNOG00000043031 0.05 0.05 2.3e-04 0.04 0.03 0.03 0.03 2.3e-04 5.8e-04 5.6e-04 8.7e-04
4 Brain intron excision ratio chr6:131043405:131043787 0.08 0.07 1.0e-05 0.05 0.05 0.04 0.05 3.2e-05 1.3e-05 4.9e-05 2.6e-05
5 Brain intron excision ratio chr6:131043426:131043787 0.08 0.07 1.2e-05 0.05 0.05 0.04 0.05 3.8e-05 1.5e-05 6.8e-05 3.7e-05
6 IL gene expression ENSRNOG00000043031 0.67 0.18 7.9e-11 0.38 0.38 0.3 0.38 3.0e-10 4.1e-10 6.0e-08 4.6e-10
7 NAcc intron excision ratio chr6:131043405:131043787 0.04 0.03 2.2e-03 0.04 0.03 0.03 0.03 6.6e-04 1.7e-03 1.6e-03 1.4e-03
8 NAcc intron excision ratio chr6:131043426:131043787 0.04 0.03 2.2e-03 0.04 0.03 0.03 0.03 6.3e-04 1.7e-03 2.0e-03 1.4e-03
9 OFC gene expression ENSRNOG00000043031 0.35 0.17 1.9e-08 0.22 0.23 0.18 0.19 7.6e-06 3.2e-06 3.7e-05 2.3e-05
10 PL gene expression ENSRNOG00000043031 0.26 0.15 2.2e-16 0.22 0.21 0.17 0.2 2.5e-16 1.3e-15 1.0e-12 7.3e-15
11 PL intron excision ratio chr6:131043405:131043787 0.03 0.03 2.1e-03 0.04 0.03 0.04 0.03 4.2e-04 5.3e-03 9.2e-04 1.8e-03
12 PL intron excision ratio chr6:131043426:131043787 0.03 0.02 7.5e-03 0.03 0.02 0.03 0.02 4.0e-03 1.6e-02 3.3e-03 7.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail2.47.78.32.9-2.92.52.9-2.92.82.8-2.82.92.72.6-2.6
BMI without tail0.51.11.71.2-1.20.31.2-1.21.30.8-0.81.21.10.7-0.8
Body weight0.21.12.0-0.51.1-1.4-0.80.8-0.6-1.41.4-1.2-0.7-0.90.9
Epididymis fat weight4.310.010.53.2-3.23.13.2-3.23.23.2-3.23.13.23.1-3.1
Glucose0.71.01.5-1.20.9-1.0-1.11.1-1.1-0.80.8-0.8-1.2-1.01.0
Heart weight0.00.00.10.30.0-0.10.0-0.00.0-0.10.1-0.10.10.0-0.1
Left kidney weight1.02.94.1-1.12.0-1.7-1.61.6-1.5-2.02.0-2.0-1.4-1.71.6
Right kidney weight0.61.62.5-0.71.5-1.3-1.11.1-1.0-1.51.5-1.6-0.9-1.21.2
Tail length3.711.214.6-2.93.4-3.8-3.13.1-2.9-3.73.7-3.4-3.1-3.43.3
Length with tail5.118.623.4-3.84.6-4.5-4.24.2-4.0-4.84.8-4.6-3.9-4.14.1
Length without tail2.35.16.4-2.12.5-2.0-2.32.3-2.2-2.52.5-2.5-2.1-1.91.9
Liver weight, left2.84.65.3-2.12.0-2.3-2.12.1-2.1-2.12.1-2.0-2.2-2.32.3
Liver weight, right0.00.00.1-0.00.1-0.2-0.10.1-0.10.4-0.4-0.1-0.10.0-0.1
Parametrial fat weight0.00.00.1-0.1-0.20.00.1-0.10.20.2-0.20.20.30.2-0.2
Retroperitoneal fat weight0.30.81.00.8-0.90.90.9-0.90.91.0-1.00.90.90.9-0.9
Intraocular pressure0.10.10.30.3-0.20.50.3-0.30.30.5-0.50.20.30.5-0.5
Extensor digitorum longus weight6.325.328.1-4.75.3-5.1-4.94.9-4.7-5.35.3-5.3-4.7-5.05.0
Soleus weight0.00.00.10.40.2-0.10.0-0.00.2-0.30.3-0.30.2-0.0-0.0
Tibialis anterior weight0.31.11.4-0.81.1-1.2-1.01.0-1.0-1.11.1-1.1-1.0-1.11.1
Tibia length0.20.71.4-1.20.7-0.7-0.90.9-0.9-0.70.7-0.6-1.0-0.80.8
Number of licking bursts0.00.00.0-0.20.00.1-0.20.1-0.20.1-0.10.0-0.2-0.10.1
Food consumed during 24 hour testing period0.20.20.3-0.40.5-0.6-0.40.4-0.3-0.50.5-0.6-0.3-0.60.5
Times rat made contact with spout0.30.40.5-0.70.4-0.6-0.60.6-0.7-0.50.5-0.4-0.7-0.70.7
Mean time between licks in bursts0.70.91.41.2-1.00.71.1-1.11.20.9-0.90.91.20.6-0.6
Mean num. licks in bursts0.10.10.2-0.20.2-0.4-0.20.2-0.1-0.40.4-0.2-0.1-0.30.3
Std. dev. time between licks in bursts0.50.51.01.0-0.40.50.8-0.81.00.6-0.60.41.00.6-0.6
Water consumed over 24 hours3.54.24.8-2.11.9-2.2-2.02.0-2.0-2.12.1-1.9-2.0-2.22.2
Indifference point 0 sec3.96.37.3-2.22.5-2.5-2.52.5-2.4-2.52.5-2.5-2.7-2.52.5
Indifference point AUC2.32.73.6-1.91.6-1.7-1.81.8-1.8-1.41.4-1.6-1.6-1.71.7
Indifference point function ln k0.60.91.6-0.71.2-0.8-0.90.9-0.6-1.31.3-1.2-0.7-0.70.7
Indifference point function log k0.60.91.6-0.71.2-0.8-0.90.9-0.6-1.31.3-1.2-0.7-0.70.7
Delay discounting total patch changes 0 sec4.47.18.3-2.32.7-2.6-2.72.7-2.6-2.72.7-2.7-2.9-2.62.7
Delay discounting total patch changes 12 sec3.95.25.9-2.32.3-2.1-2.42.4-2.4-2.12.1-2.3-2.4-2.32.3
Delay discounting total patch changes 18 sec1.62.12.9-1.71.4-1.3-1.61.6-1.7-1.01.0-1.3-1.6-1.51.6
Delay discounting total patch changes 24 sec0.20.30.4-0.40.5-0.6-0.60.6-0.6-0.40.4-0.5-0.6-0.60.6
Delay discounting total patch changes 6 sec2.43.75.3-1.61.7-2.2-1.91.9-1.9-1.81.8-1.7-2.1-2.32.3
Delay discounting time to switch 0 sec11.517.619.04.2-4.14.44.2-4.24.14.3-4.34.14.14.2-4.2
Delay discounting water rate 0 sec19.931.633.4-5.45.5-5.8-5.75.7-5.5-5.65.6-5.5-5.7-5.85.8
Delay discounting water rate 12 sec10.916.419.3-3.74.1-4.3-3.93.9-3.7-4.44.4-4.1-3.8-4.14.1
Delay discounting water rate 18 sec5.37.07.8-2.52.7-2.5-2.62.6-2.5-2.82.8-2.7-2.6-2.62.6
Delay discounting water rate 24 sec4.46.17.6-2.32.5-2.5-2.42.4-2.2-2.82.8-2.5-2.3-2.52.5
Delay discounting water rate 6 sec5.37.79.0-2.62.7-3.0-2.72.7-2.5-3.03.0-2.7-2.5-2.92.9
Locomotor activity0.10.20.3-0.20.5-0.3-0.50.5-0.4-0.30.3-0.5-0.5-0.40.4
Locomotor testing distance0.40.60.8-0.50.8-0.6-0.90.9-0.8-0.70.7-0.8-0.9-0.70.7
Locomotor testing rearing1.32.13.51.5-1.51.51.3-1.31.21.9-1.91.51.11.4-1.3
Light reinforcement 10.00.00.10.10.0-0.00.0-0.00.1-0.20.2-0.00.0-0.20.2
Light reinforcement 21.72.22.81.4-1.71.41.6-1.61.61.4-1.41.71.61.2-1.2
Reaction time number correct3.44.96.5-2.12.2-2.0-2.32.3-2.2-2.52.5-2.2-2.2-2.02.0
Reaction time mean minus median0.30.40.70.4-0.40.80.5-0.50.50.9-0.90.40.60.6-0.7
Reaction time mean minus median AUC0.20.30.50.4-0.30.70.5-0.50.50.7-0.70.20.60.6-0.6
Reaction time num false alarms1.11.51.9-0.91.2-1.3-1.21.2-1.1-1.41.4-1.1-1.3-1.21.3
Reaction time num false alarms AUC1.52.22.7-1.21.4-1.5-1.41.4-1.4-1.61.6-1.4-1.5-1.51.5
Reaction time trials correct on left3.44.96.5-2.12.2-2.0-2.32.3-2.2-2.52.5-2.2-2.2-2.02.0
Reaction time trials on left3.44.86.4-2.12.2-2.0-2.22.2-2.2-2.52.5-2.2-2.2-1.92.0
Reaction time mean1.21.62.61.1-1.11.31.2-1.21.21.6-1.61.01.31.2-1.2
Reaction time mean AUC0.81.01.70.9-0.81.10.9-0.90.91.3-1.30.81.11.0-1.0
Median of all reaction times0.60.81.40.8-0.70.90.9-0.90.91.2-1.20.71.00.8-0.8
Reaction time omissions0.70.91.6-1.21.3-0.7-1.11.1-1.1-0.70.7-1.3-0.9-0.70.7
Reaction time false alarm rate0.10.10.3-0.20.3-0.5-0.30.3-0.3-0.40.4-0.3-0.4-0.50.5
Reaction time premature initiation rate0.91.21.6-1.01.0-1.3-1.11.1-1.1-0.90.9-1.0-1.2-1.31.3
Reaction time premature initiations2.84.04.4-1.81.9-2.1-2.02.0-2.0-2.02.0-1.9-2.1-2.02.0
Std. dev. reaction times0.60.91.50.7-0.71.10.9-0.90.91.2-1.20.70.91.0-1.0
Reaction time trials completed3.44.86.4-2.12.2-2.0-2.22.2-2.2-2.52.5-2.2-2.2-1.92.0
Reaction time trials AUC3.75.26.9-2.12.3-2.1-2.32.3-2.3-2.62.6-2.3-2.3-2.02.0
Social response proportion0.50.60.8-0.50.7-0.9-0.70.7-0.7-0.80.8-0.7-0.7-0.80.8
Social responses0.00.00.10.3-0.10.00.2-0.20.10.2-0.20.10.1-0.10.1
Social time1.21.62.3-1.21.4-1.3-1.11.1-1.1-1.51.5-1.4-1.0-1.21.2
Conditioned locomotion1.31.62.0-1.41.3-1.2-1.31.3-1.2-1.21.2-1.3-1.2-1.21.3
Cocaine response after cond. corrected0.60.71.00.9-1.00.70.9-0.90.90.9-0.91.00.80.7-0.7
Cocaine response after cond. not corrected2.02.22.71.5-1.61.41.5-1.51.51.5-1.51.71.41.3-1.3
Cocaine response before conditioning2.22.73.01.7-1.61.71.7-1.71.61.6-1.61.51.71.7-1.7
Saline control response0.20.20.40.6-0.30.40.5-0.50.60.5-0.50.30.50.4-0.4
Condit. Reinf. active minus inactive responses0.70.81.3-0.60.9-1.0-0.80.8-0.9-0.90.9-1.0-0.8-1.21.1
Condit. Reinf. active-inactive response ratio0.80.81.3-0.60.9-1.1-0.70.7-0.8-0.90.9-0.9-0.8-1.21.1
Condit. Reinf. active responses0.00.10.30.10.2-0.4-0.10.1-0.2-0.20.2-0.2-0.1-0.50.4
Condit. Reinf. inactive responses0.50.60.90.9-0.80.70.9-0.90.80.7-0.70.80.90.7-0.7
Condit. Reinf. lever presses1.11.62.71.6-1.21.01.4-1.41.41.1-1.11.11.40.9-1.0
Condit. Reinf. lever reinforcers received0.10.10.30.20.3-0.4-0.10.1-0.2-0.30.3-0.3-0.1-0.60.5
Pavlov. Cond. lever latency1.72.43.3-1.81.5-1.3-1.71.7-1.7-1.31.3-1.5-1.7-1.31.3
Pavlov. Cond. magazine entry latency4.65.36.62.6-2.32.12.4-2.42.42.1-2.12.32.42.2-2.2
Pavlov. Cond. change in total contacts3.65.16.22.5-2.32.12.4-2.42.22.2-2.22.32.32.1-2.1
Pavlov. Cond. index score4.25.57.52.7-2.32.12.5-2.52.52.1-2.12.32.52.1-2.2
Pavlov. Cond. latency score4.25.47.02.6-2.32.12.5-2.52.52.1-2.12.32.52.1-2.2
Pavlov. Cond. lever contacts2.53.44.82.2-1.91.62.1-2.12.01.5-1.51.82.11.6-1.6
Pavlov. Cond. magazine entry number3.24.05.6-2.42.0-1.8-2.22.2-2.1-1.81.8-2.0-2.1-1.81.8
Pavlov. Cond. intertrial magazine entries5.87.47.7-2.82.7-2.7-2.82.8-2.8-2.72.7-2.7-2.7-2.72.7
Pavlov. Cond. lever-magazine prob. diff.4.66.08.12.8-2.52.22.6-2.62.62.2-2.22.42.62.2-2.2
Pavlov. Cond. response bias3.14.36.42.5-2.11.82.3-2.32.31.7-1.72.02.31.8-1.8
Conditioned reinforcement - actives2.52.43.0-1.51.5-1.7-1.51.5-1.5-1.61.6-1.5-1.5-1.61.6
Conditioned reinforcement - inactives0.40.40.6-0.60.7-0.8-0.60.6-0.6-0.60.6-0.7-0.6-0.60.6
Conditioned locomotion0.50.60.90.8-0.70.60.9-0.90.90.5-0.50.70.90.8-0.8
Intermittent access intake day 1-15 change1.41.41.71.2-1.31.01.2-1.21.11.2-1.21.31.21.1-1.1
Intermittent access intake escalation1.51.51.81.2-1.31.11.3-1.31.21.2-1.21.31.31.2-1.2
Intermittent access intake escalation 20.20.20.30.2-0.60.30.4-0.40.40.5-0.50.60.40.4-0.4
Intermitt. access day 1 inactive lever presses2.83.03.4-1.51.8-1.7-1.81.8-1.7-1.71.7-1.9-1.8-1.71.7
Intermitt. access day 15 inactive lever presses1.01.11.4-0.81.1-1.2-1.01.0-1.1-0.90.9-1.1-1.0-1.11.2
Intermitt. access escalation Index0.30.30.4-0.40.5-0.5-0.60.6-0.7-0.30.3-0.5-0.6-0.60.6
Intermittent access day 1 total infusions0.30.30.50.7-0.50.30.6-0.60.60.5-0.50.50.70.6-0.6
Intermittent access day 15 total infusions1.71.92.21.5-1.41.11.4-1.41.31.3-1.31.41.41.4-1.4
Intermittent access terminal intake (last 3 days)2.02.22.51.6-1.61.21.5-1.51.41.5-1.51.61.51.4-1.4
Intermittent access total infusions0.60.61.11.0-0.80.50.9-0.90.80.7-0.70.80.80.8-0.7
Intermittent access day 1 locomotion0.70.81.11.1-0.80.60.9-0.91.00.7-0.70.81.00.9-0.9
Intermittent access day 15 total locomotion0.20.20.40.6-0.40.10.6-0.60.60.3-0.30.40.70.4-0.4
Intermittent access total locomotion0.30.40.60.7-0.60.30.7-0.70.70.6-0.60.60.70.6-0.6
Intermittent access standard deviation3.33.54.11.9-2.01.62.0-2.01.91.7-1.72.02.01.8-1.8
Cocaine induced anxiety2.83.23.6-1.71.7-1.8-1.81.8-1.9-1.71.7-1.6-1.9-1.91.9
Post-drug Anxiety2.32.53.0-1.61.4-1.7-1.61.6-1.7-1.41.4-1.4-1.7-1.71.7
Baseline Anxiety1.61.72.21.1-1.31.31.3-1.31.31.5-1.51.41.31.3-1.3
Lifetime Intake0.20.20.50.7-0.50.10.6-0.60.50.3-0.30.50.60.4-0.4
Incentive Sensitization - Responses0.00.00.00.2-0.0-0.00.1-0.10.1-0.10.10.00.10.1-0.1
Incentive Sensitization - Breakpoint0.00.00.00.10.1-0.2-0.00.0-0.0-0.20.2-0.1-0.0-0.00.0
Progressive ratio test 1 active lever presses0.00.00.00.2-0.1-0.10.1-0.10.10.1-0.10.10.10.1-0.0
Progressive ratio test 1 breakpoint0.10.10.10.3-0.30.00.3-0.30.30.3-0.30.30.30.2-0.2
Progressive ratio test 1 inactive lever presses2.93.13.5-1.71.9-1.7-1.81.8-1.8-1.71.7-1.9-1.8-1.71.7
Progressive ratio test 2 active lever presses0.00.00.10.2-0.0-0.20.1-0.10.0-0.00.00.00.0-0.00.1
Progressive ratio test 2 breakpoint0.00.00.10.20.1-0.30.0-0.00.0-0.20.2-0.10.0-0.10.1
Progressive ratio test 2 inactive lever presses0.91.11.4-0.91.0-1.2-1.11.1-1.1-0.90.9-1.0-1.1-1.11.1
Total sessions with >9 infusions0.00.00.10.2-0.1-0.30.1-0.10.2-0.10.10.10.1-0.10.1
Short access day 1 total inactive lever presses0.00.00.10.30.1-0.20.1-0.10.2-0.20.2-0.10.20.0-0.0
Short access day 10 total inactive lever presses0.40.50.8-0.50.9-0.6-0.70.7-0.7-0.70.7-0.9-0.6-0.60.6
Short access day 1 total infusions0.40.51.0-0.50.6-1.0-0.60.6-0.5-0.80.8-0.6-0.5-0.70.7
Short access day 10 total infusions0.30.30.70.8-0.60.10.6-0.60.60.3-0.30.60.60.5-0.5
Short access total infusions0.10.10.30.5-0.4-0.10.4-0.40.40.1-0.10.40.40.2-0.2
Short access day 1 locomotion0.40.40.90.9-0.70.30.7-0.70.80.4-0.40.60.70.6-0.6
Short access day 10 total locomotion0.60.60.80.9-0.80.60.8-0.80.70.9-0.90.80.80.7-0.7
Short access total locomotion0.00.00.10.3-0.2-0.10.2-0.20.20.1-0.10.20.20.0-0.1
Compulsive drug intake0.00.00.10.2-0.00.40.1-0.10.00.0-0.00.00.20.3-0.3
One hour access (0.3 mA shock)0.10.20.5-0.10.3-0.7-0.30.3-0.4-0.40.4-0.3-0.3-0.40.5
One hour access (shock baseline)0.00.00.10.2-0.2-0.20.1-0.10.1-0.00.00.20.1-0.00.0
Number of responses in last shaping day0.40.40.60.5-0.70.50.8-0.80.70.5-0.50.70.80.6-0.6
Context. condit. distance diff. score2.53.13.9-1.51.9-1.8-1.61.6-1.6-1.91.9-2.0-1.3-1.91.9
Locomotion velocity, session 10.20.20.3-0.40.4-0.3-0.40.4-0.6-0.50.5-0.4-0.3-0.40.4
Locomotion distance, session 10.50.60.80.6-0.80.90.8-0.80.60.8-0.80.80.80.9-0.9
Locomotion velocity, session 20.00.00.10.00.1-0.3-0.10.1-0.2-0.40.4-0.1-0.1-0.20.2
Locomotion distance, session 20.30.40.60.8-0.60.60.7-0.70.60.5-0.50.60.70.7-0.7
Locomotion velocity, session 30.10.20.30.3-0.40.40.4-0.40.30.5-0.50.40.40.5-0.5
Locomotion distance, session 30.00.00.0-0.10.10.0-0.10.1-0.20.0-0.0-0.1-0.00.1-0.1
Stereotopy head waving bouts, day 30.10.20.3-0.50.3-0.4-0.40.4-0.4-0.40.4-0.3-0.4-0.40.4
Stereotopy head waving duration, day 30.30.30.5-0.60.5-0.7-0.50.5-0.5-0.60.6-0.4-0.6-0.60.6
Locomotion velocity, session 70.30.30.50.5-0.50.70.4-0.40.30.7-0.70.50.50.7-0.7
Locomotion distance, session 70.81.01.11.0-1.01.01.0-1.00.91.1-1.10.91.01.0-1.0
Stereotopy head waving bouts, day 71.01.21.4-1.11.2-1.0-1.11.1-1.0-1.11.1-1.2-1.2-0.90.9
Stereotopy head waving duration, day 70.40.40.6-0.70.7-0.6-0.70.7-0.6-0.70.7-0.7-0.8-0.50.5
Locomotion velocity, session 80.40.40.7-0.40.8-0.7-0.60.6-0.6-0.60.6-0.8-0.5-0.80.8
Locomotion distance, session 80.00.10.10.20.3-0.20.0-0.00.1-0.30.3-0.40.3-0.30.2
Degree of sensitization distance0.20.20.20.3-0.40.50.3-0.30.30.5-0.50.40.30.4-0.4
Degree of sensitization stereotypy0.20.20.3-0.50.5-0.2-0.50.5-0.4-0.40.4-0.5-0.5-0.20.1
Condit. Reinf. active minus inactive responses0.60.60.80.8-0.90.60.8-0.80.90.7-0.70.90.80.7-0.7
Condit. Reinf. active-inactive response ratio2.83.03.21.6-1.81.61.7-1.71.81.8-1.81.81.81.7-1.7
Condit. Reinf. active responses0.10.10.20.5-0.50.10.4-0.40.40.2-0.20.50.50.2-0.2
Condit. Reinf. inactive responses2.02.43.0-1.61.4-1.6-1.51.5-1.7-1.71.7-1.4-1.5-1.61.5
Incentive salience index mean0.60.70.80.7-0.90.70.8-0.80.80.8-0.80.90.80.8-0.8
Condit. Reinf. lever presses0.10.20.30.2-0.40.40.4-0.40.30.5-0.50.40.40.5-0.5
Time in familiar zone, hab. session 10.30.30.60.8-0.30.60.5-0.50.60.7-0.70.30.50.6-0.6
Time in novel zone, hab. session 10.20.20.30.2-0.50.40.5-0.50.30.4-0.40.50.50.4-0.4
Total zone transitions, hab. session 10.40.61.01.0-0.60.80.9-0.90.90.6-0.60.51.00.7-0.8
Total locomotion distance, hab. session 10.10.20.4-0.00.6-0.5-0.30.3-0.1-0.50.5-0.7-0.2-0.50.5
Locomotion velocity, hab. session 10.70.91.2-0.71.1-1.1-0.80.9-0.7-1.11.1-1.1-0.8-1.11.1
Time in familiar zone, hab. session 20.40.40.70.8-0.50.70.5-0.50.60.6-0.60.50.50.6-0.6
Time in novel zone, hab. session 20.00.00.10.1-0.30.00.3-0.30.30.1-0.10.30.30.1-0.1
Total zone transitions, hab. session 20.81.01.11.0-1.01.01.0-1.00.91.0-1.01.01.11.0-1.0
Total locomotion distance, hab. session 20.30.40.5-0.60.6-0.7-0.60.6-0.7-0.60.6-0.6-0.6-0.70.7
Locomotion velocity, hab. session 20.50.70.8-0.80.8-0.9-0.80.8-0.9-0.70.7-0.8-0.8-0.90.9
Novel to familiar place preference ratio0.50.50.80.4-0.80.90.7-0.70.70.7-0.70.80.70.9-0.8
Novelty place preference0.30.30.50.3-0.60.70.5-0.50.50.5-0.50.60.50.7-0.6
Time in novel zone, NPP test0.20.20.40.2-0.50.60.5-0.50.50.5-0.50.50.50.6-0.6
Total zone transitions, NPP test0.10.10.30.5-0.00.30.4-0.40.40.2-0.2-0.00.50.3-0.3
Total locomotion distance, NPP test0.00.00.2-0.10.4-0.2-0.10.1-0.1-0.10.1-0.4-0.0-0.20.2
Locomotion velocity, NPP test0.10.10.2-0.20.4-0.4-0.20.2-0.2-0.20.2-0.5-0.1-0.30.3
Pavlov. Cond. lever latency0.81.01.2-0.91.0-0.9-0.90.9-1.0-1.01.0-1.0-1.0-1.11.1
Pavlov. Cond. magazine entry latency0.70.91.40.7-0.81.20.8-0.80.81.1-1.10.80.81.1-1.1
Pavlov. Cond. change in total contacts0.30.30.50.5-0.50.60.5-0.50.40.7-0.70.60.50.6-0.6
Pavlov. Cond. index score1.21.52.01.0-1.21.41.1-1.11.11.4-1.41.21.21.4-1.4
Pavlov. Cond. latency score0.81.01.40.8-1.01.10.9-0.90.91.2-1.21.00.91.1-1.1
Pavlov. Cond. lever contacts1.11.31.60.9-1.21.21.1-1.11.01.3-1.31.21.01.2-1.3
Pavlov. Cond. magazine entry number1.11.41.5-1.11.1-1.2-1.21.2-1.2-1.21.2-1.1-1.2-1.21.1
Pavlov. Cond. intertrial magazine entries6.27.48.4-2.52.7-2.9-2.62.6-2.6-2.92.9-2.7-2.6-2.82.8
Pavlov. Cond. lever-magazine prob. diff.1.01.21.60.8-1.01.21.0-1.01.01.3-1.31.01.01.2-1.2
Pavlov. Cond. response bias1.31.61.71.1-1.21.31.2-1.21.21.3-1.31.21.31.3-1.3
Bone: apparent density0.10.10.30.2-0.20.40.2-0.20.20.6-0.60.20.30.4-0.4
Bone surface0.10.10.20.1-0.20.40.3-0.30.20.4-0.40.20.30.4-0.4
Bone volume0.00.10.10.1-0.20.20.3-0.30.20.4-0.40.20.30.3-0.3
Bone: connectivity density0.10.10.3-0.30.5-0.1-0.30.3-0.3-0.20.2-0.5-0.2-0.10.1
Bone: cortical apparent density8.511.112.0-3.43.3-3.2-3.43.4-3.5-3.23.2-3.2-3.4-3.33.4
Bone: cortical area0.71.01.6-1.30.8-1.2-1.01.0-1.1-0.60.6-0.8-1.1-1.21.1
Bone: cortical porosity0.10.10.2-0.10.4-0.1-0.10.1-0.0-0.40.4-0.40.1-0.20.1
Bone: cortical porosity0.10.10.40.5-0.10.40.4-0.40.50.1-0.10.10.60.4-0.4
Bone: cortical thickness0.50.91.7-1.30.8-1.0-1.01.0-1.2-0.60.6-0.7-1.1-1.00.9
Bone: cortical thickness0.60.70.9-0.90.9-0.9-0.80.8-0.7-0.90.9-0.9-0.8-0.80.9
Bone: cortical tissue density8.711.412.1-3.43.3-3.3-3.53.5-3.5-3.23.2-3.3-3.4-3.43.4
Bone: elastic displacement0.50.50.6-0.70.8-0.6-0.80.8-0.8-0.80.8-0.8-0.8-0.70.7
Bone: elastic work0.10.10.2-0.10.3-0.2-0.30.3-0.3-0.50.5-0.3-0.3-0.30.2
Bone: endosteal estimation0.10.30.60.8-0.40.40.7-0.70.70.2-0.20.40.70.3-0.3
Bone: endosteal perimeter0.00.00.10.2-0.2-0.30.2-0.20.20.1-0.10.10.1-0.40.3
Bone: final force0.20.40.5-0.60.6-0.7-0.60.6-0.6-0.70.7-0.6-0.5-0.70.7
Bone: final moment0.30.50.7-0.70.7-0.7-0.60.6-0.7-0.80.8-0.7-0.6-0.80.7
Bone: marrow area0.10.20.50.7-0.40.30.6-0.60.70.2-0.20.30.60.3-0.3
Bone: maximum diameter0.00.10.1-0.3-0.2-0.2-0.00.0-0.00.4-0.40.3-0.2-0.20.2
Bone: maximum force0.20.40.6-0.60.6-0.7-0.60.6-0.7-0.60.6-0.6-0.6-0.70.7
Bone: maximum moment0.20.40.5-0.60.6-0.6-0.50.5-0.6-0.60.6-0.6-0.5-0.70.6
Bone: minimum diameter0.81.62.1-1.11.2-1.5-1.11.1-1.1-1.31.3-1.3-1.1-1.51.4
Bone: periosteal estimation0.10.10.3-0.40.3-0.6-0.20.2-0.3-0.30.3-0.3-0.3-0.60.6
Bone: periosteal perimeter0.10.10.3-0.20.0-0.5-0.10.1-0.1-0.00.00.0-0.2-0.60.5
Bone: post-yield work1.31.72.6-1.11.6-1.2-1.41.4-1.2-1.31.3-1.6-1.3-1.21.2
Bone: stiffness1.52.32.8-1.51.5-1.7-1.51.5-1.5-1.31.3-1.5-1.4-1.71.7
Bone: tissue strength0.00.00.1-0.20.00.1-0.20.1-0.20.2-0.20.0-0.4-0.00.0
Bone: trabecular number0.00.10.2-0.20.4-0.2-0.30.3-0.3-0.10.1-0.4-0.2-0.20.2
Bone: trabecular spacing0.10.10.20.2-0.40.10.4-0.40.50.1-0.10.40.30.1-0.1
Bone: trabecular thickness0.10.10.2-0.40.3-0.2-0.30.3-0.4-0.10.1-0.3-0.4-0.20.2
Bone: trabecular tissue density0.20.20.6-0.60.3-0.3-0.60.6-0.8-0.10.1-0.2-0.7-0.30.4
Breakpoint value in progressive ratio session0.10.10.2-0.0-0.40.20.2-0.20.10.4-0.40.40.20.1-0.1
Distance traveled before self-admin0.20.20.60.2-0.50.10.2-0.20.20.8-0.80.50.20.2-0.2
Distance traveled after self-admin0.50.60.9-0.70.8-1.0-0.70.7-0.7-0.70.7-0.8-0.5-0.90.9
Delta time in closed arm before/after self-admin0.00.00.10.3-0.1-0.00.2-0.20.3-0.00.00.00.30.1-0.1
Delta time in open arm before/after self-admin0.40.40.6-0.70.6-0.5-0.60.6-0.7-0.40.4-0.5-0.8-0.70.7
Diff in mean of infusions in LGA sessions0.00.00.0-0.2-0.1-0.0-0.10.1-0.10.1-0.10.2-0.2-0.10.1
Extinction: sum of active levers before priming0.00.00.1-0.0-0.30.10.1-0.10.00.1-0.10.30.20.0-0.0
Active lever presses in extinction session 61.61.52.1-1.11.2-1.3-1.11.1-1.0-1.51.5-1.3-1.2-1.21.2
Delta distance traveled before/after self-admin0.10.20.5-0.20.5-0.3-0.20.2-0.2-0.70.7-0.5-0.0-0.30.3
Delta ambulatory time before/after self-admin0.91.01.8-0.81.1-0.9-0.80.8-0.8-1.31.3-1.2-0.7-0.90.9
Time in closed arm before self-admin3.43.94.21.9-2.12.12.0-2.01.92.1-2.12.11.81.9-1.9
Time in closed arm after self-admin1.51.62.01.4-1.21.31.3-1.31.41.2-1.21.21.21.3-1.3
Time in open arm before self-admin6.16.58.8-2.32.6-3.0-2.52.5-2.3-2.62.6-2.6-2.3-2.52.5
Time in open arm after self-admin3.74.14.7-1.92.0-2.2-2.02.0-1.9-2.02.0-2.0-2.0-2.12.1
Sum of active levers in priming session hrs 5-60.20.20.60.4-0.70.30.5-0.50.40.5-0.50.80.40.3-0.3
Time to tail flick, vehicle, before self-admin0.50.50.6-0.70.8-0.7-0.70.7-0.7-0.60.6-0.7-0.7-0.50.6
Time to tail flick, vehicle, after self-admin0.10.10.30.4-0.10.40.3-0.30.5-0.30.30.10.30.6-0.5
Time to tail flick, test, before self-admin0.10.10.1-0.30.2-0.4-0.30.3-0.3-0.00.0-0.2-0.3-0.30.3
Time to tail flick, test, after self-admin1.71.82.2-1.41.4-1.2-1.41.4-1.3-1.51.5-1.4-1.2-1.21.2
Delta time to tail flick, vehicle, before/after SA0.00.00.10.2-0.10.30.2-0.20.2-0.10.10.10.20.2-0.2
Delta time to tail flick, test, before/after SA1.11.01.9-0.91.1-0.9-0.90.9-0.8-1.41.4-1.1-0.7-0.80.8
Ambulatory time before self-admin0.30.30.90.4-0.70.40.3-0.30.31.0-1.00.70.10.4-0.4
Ambulatory time after self-admin0.00.00.00.1-0.1-0.10.1-0.10.10.2-0.20.10.2-0.10.1
Total heroin consumption0.81.01.6-1.20.8-1.1-1.01.0-1.2-0.70.7-0.7-1.0-1.11.1
Area under the delay curve0.10.10.30.3-0.20.30.2-0.20.20.5-0.50.20.30.0-0.0
Delay disc. indifference point, 0s delay0.20.20.3-0.30.4-0.4-0.40.4-0.3-0.40.4-0.4-0.4-0.50.6
Delay disc. indifference point, 16s delay0.10.10.20.0-0.2-0.20.1-0.10.20.3-0.30.2-0.1-0.50.5
Delay disc. indifference point, 2s delay0.20.20.60.4-0.50.60.3-0.30.30.8-0.80.50.30.3-0.3
Delay disc. indifference point, 24s delay0.20.20.50.2-0.40.70.3-0.30.30.6-0.60.40.30.5-0.5
Delay disc. indifference point, 4s delay0.20.20.2-0.30.5-0.3-0.40.4-0.4-0.40.4-0.5-0.4-0.50.5
Delay disc. indifference point, 8s delay0.20.20.40.5-0.20.30.3-0.30.40.6-0.60.20.50.3-0.3
Delay discount exponential model param0.00.10.2-0.20.1-0.2-0.10.1-0.2-0.40.4-0.1-0.2-0.00.0
Delay discount hyperbolic model param0.10.10.3-0.30.2-0.4-0.20.2-0.2-0.50.5-0.2-0.3-0.10.1
Fecal boli incidents, locomotor time 12.62.84.11.2-1.72.01.6-1.61.61.9-1.91.71.61.6-1.6
Change in fecal boli incidents, locomotor task1.61.53.9-0.11.1-1.8-0.70.7-0.5-2.02.0-1.2-0.6-1.11.1
Time >=10cm from walls, locomotor time 10.30.30.60.8-0.50.30.7-0.70.70.0-0.00.50.60.5-0.5
Bouts of movement, locomotor time 11.92.24.30.7-1.42.11.3-1.31.21.9-1.91.41.21.4-1.3
Total resting periods, locomotor time 11.82.03.90.8-1.32.01.3-1.31.21.8-1.81.41.21.4-1.3
Rest time, locomotor task time 10.10.10.2-0.50.10.0-0.30.3-0.40.3-0.3-0.1-0.3-0.10.2
Distance moved, locomotor task time 10.10.10.60.8-0.40.10.4-0.40.4-0.10.10.30.30.3-0.4
Vertical activity count, locomotor time 10.60.71.0-0.70.8-0.7-0.90.9-0.9-0.70.7-0.7-1.0-0.90.9
Time >=10cm from walls, locomotor time 20.40.50.9-0.80.7-0.3-0.80.8-0.8-0.50.5-0.7-0.9-0.60.7
Bouts of movement, locomotor time 21.92.02.9-1.71.4-1.2-1.41.4-1.3-1.21.2-1.4-1.4-1.71.7
Total resting periods, locomotor time 21.51.62.5-1.41.2-1.1-1.21.2-1.1-1.01.0-1.2-1.2-1.61.6
Rest time, locomotor task time 20.20.30.6-0.40.4-0.8-0.50.5-0.5-0.50.5-0.4-0.5-0.60.6
Distance moved, locomotor task time 20.20.20.60.5-0.40.80.4-0.40.30.5-0.50.40.30.6-0.6
Vertical activity count, locomotor time 20.30.30.7-0.80.5-0.0-0.70.7-0.8-0.10.1-0.5-0.7-0.50.5
Weight adjusted by age0.10.10.5-0.20.4-0.1-0.20.2-0.2-0.70.7-0.4-0.20.0-0.1
Seeking ratio, delayed vs. immediate footshock0.30.30.8-0.90.6-0.4-0.50.5-0.4-0.80.8-0.6-0.6-0.10.1
Locomotion in novel chamber5.87.28.2-2.32.8-2.8-2.62.6-2.6-2.92.9-2.8-2.7-2.62.6
Locomotion in novel chamber post-restriction0.10.10.40.1-0.2-0.00.4-0.40.50.2-0.20.10.60.0-0.1
Progressive ratio0.60.71.6-0.70.6-1.2-0.70.7-0.6-1.11.1-0.6-0.6-0.90.9
Food seeking constrained by brief footshock1.11.42.0-1.41.1-0.9-1.31.3-1.3-0.40.4-1.1-1.4-1.31.3
Seeking ratio, punishment vs. effort0.10.10.3-0.20.20.4-0.30.3-0.30.5-0.5-0.2-0.3-0.00.1
Run reversals in cocaine runway, females1.41.42.61.1-1.11.61.1-1.10.91.3-1.31.21.11.1-1.1
Run reversals in cocaine runway, males0.70.71.3-1.10.7-0.7-0.90.9-1.0-0.20.2-0.7-0.9-1.11.0
Latency to leave start box in cocaine runway0.10.10.20.1-0.50.20.3-0.30.20.1-0.10.50.40.1-0.1
Latency to leave start box in cocaine runway, F0.20.20.40.2-0.60.50.3-0.30.10.6-0.60.60.40.2-0.1
Latency to leave start box in cocaine runway, M0.10.10.20.1-0.50.00.3-0.30.30.2-0.20.50.20.1-0.1
Cd content in liver0.70.81.6-0.51.2-1.0-0.70.7-0.5-1.01.0-1.3-0.5-1.01.0
Co content in liver1.11.31.7-0.81.2-1.2-1.11.1-1.0-1.21.2-1.2-1.0-1.31.3
Cu content in liver1.11.42.01.2-1.41.11.2-1.21.11.0-1.01.41.11.1-1.1
Fe content in liver0.30.30.60.4-0.60.70.4-0.40.30.6-0.60.60.40.8-0.8
K content in liver0.10.10.2-0.50.3-0.4-0.30.3-0.4-0.40.4-0.3-0.4-0.30.3
Mg content in liver0.30.30.5-0.40.4-0.7-0.40.4-0.4-0.70.7-0.4-0.4-0.70.6
Mn content in liver0.20.20.5-0.30.5-0.6-0.30.3-0.2-0.70.7-0.6-0.1-0.60.5
Na content in liver0.10.10.30.0-0.50.50.2-0.20.00.4-0.40.50.10.4-0.4
Rb content in liver0.91.21.5-0.91.2-1.1-1.01.1-1.0-1.21.2-1.2-1.0-1.11.1
Se content in liver0.10.10.20.4-0.30.30.4-0.40.40.2-0.20.30.50.4-0.4
Sr content in liver0.30.30.4-0.30.6-0.6-0.50.5-0.4-0.60.6-0.6-0.4-0.60.6
Zn content in liver0.20.30.5-0.40.4-0.6-0.40.4-0.4-0.70.7-0.4-0.4-0.60.6