Prp2l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000042833 0.17 0.06 0.0e+00 0.16 0.14 0.16 0.16 4.7e-17 1.1e-15 2.4e-17 3.9e-17
2 Adipose mRNA stability ENSRNOG00000042833 0.04 0.03 4.3e-03 0.01 0.01 0.01 0.01 5.0e-02 4.5e-02 9.5e-03 2.7e-02
3 BLA gene expression ENSRNOG00000042833 0.28 0.1 9.5e-13 0.24 0.23 0.19 0.24 4.8e-13 7.8e-13 1.7e-10 3.2e-13
4 BLA mRNA stability ENSRNOG00000042833 0.07 0.04 1.6e-03 0.03 0.03 0.02 0.02 7.5e-03 1.1e-02 4.2e-02 4.1e-02
5 Brain gene expression ENSRNOG00000042833 0.23 0.06 0.0e+00 0.22 0.28 0.29 0.29 2.1e-20 2.6e-26 1.2e-26 1.1e-26
6 Brain intron excision ratio chr10:88469122:88493568 0.11 0.05 2.4e-06 0.03 0.06 0.06 0.06 1.3e-03 1.6e-06 6.0e-06 1.3e-06
7 Brain mRNA stability ENSRNOG00000042833 0.26 0.11 5.6e-17 0.17 0.19 0.18 0.18 1.7e-15 3.1e-17 1.7e-16 9.6e-17
8 IL gene expression ENSRNOG00000042833 0.21 0.11 3.9e-03 0.03 0.09 0.05 0.05 8.4e-02 3.0e-03 2.1e-02 2.8e-02
9 IL intron excision ratio chr10:88495638:88504726 0.41 0.13 6.3e-05 0 0.2 0.14 0.12 2.8e-01 1.9e-05 4.0e-04 8.3e-04
10 IL mRNA stability ENSRNOG00000042833 0.22 0.11 2.6e-03 0.12 0.07 0.09 0.1 8.0e-04 7.7e-03 2.9e-03 2.2e-03
11 LHb gene expression ENSRNOG00000042833 0.35 0.12 7.7e-05 0.13 0.18 0.22 0.22 4.8e-04 5.7e-05 7.2e-06 5.1e-06
12 NAcc gene expression ENSRNOG00000042833 0.18 0.07 1.8e-10 0.14 0.12 0.12 0.11 1.2e-10 4.5e-09 2.7e-09 9.6e-09
13 NAcc intron excision ratio chr10:88469122:88493568 0.18 0.07 3.5e-09 0.13 0.13 0.13 0.13 1.1e-09 1.3e-09 9.6e-10 1.0e-09
14 NAcc intron excision ratio chr10:88495638:88504726 0.09 0.04 1.5e-05 0.07 0.04 0.05 0.06 3.4e-06 5.3e-04 1.6e-04 2.3e-05
15 NAcc mRNA stability ENSRNOG00000042833 0.11 0.05 2.9e-05 0.05 0.04 0.04 0.05 1.5e-04 2.9e-04 1.1e-03 9.0e-05
16 OFC gene expression ENSRNOG00000042833 0.26 0.12 1.3e-03 0.01 0.07 0.03 0.03 1.5e-01 1.0e-02 7.4e-02 5.9e-02
17 OFC mRNA stability ENSRNOG00000042833 0.23 0.11 4.2e-03 0.14 0.09 0.07 0.09 3.4e-04 3.9e-03 9.5e-03 4.6e-03
18 PL gene expression ENSRNOG00000042833 0.2 0.07 1.9e-15 0.2 0.19 0.19 0.19 3.3e-15 4.0e-14 3.3e-14 1.8e-14
19 PL intron excision ratio chr10:88469122:88493568 0.07 0.04 1.9e-03 0.03 0.01 0.02 0.01 4.6e-03 3.3e-02 1.5e-02 9.6e-02
20 PL mRNA stability ENSRNOG00000042833 0.06 0.03 6.8e-04 0.04 0.03 0.02 0.04 6.9e-04 2.7e-03 5.5e-03 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
BMI with tail2.37.517.80.1-0.7-2.2-2.9-3.54.2-3.2-3.4-0.7-1.6-3.3-1.74.2-1.9-2.5-3.0-2.6-2.04.1-2.3
BMI without tail0.81.67.00.20.2-0.70.3-1.52.6-2.0-0.8-0.1-0.3-1.3-0.42.4-0.7-1.4-0.6-1.2-0.52.2-0.8
Body weight3.113.126.8-1.7-2.4-3.9-1.7-4.75.2-5.0-3.6-1.3-3.3-3.8-3.44.2-3.3-4.2-2.9-3.7-3.63.7-3.7
Epididymis fat weight0.92.14.4-0.7-1.1-1.5-0.6-1.82.0-2.1-1.3-0.7-1.4-1.2-1.41.9-1.3-1.9-1.1-1.1-1.41.6-1.8
Glucose0.20.20.80.90.80.4-0.90.00.10.4-0.30.30.5-0.20.30.50.50.6-0.40.20.40.30.6
Heart weight4.36.210.0-1.4-2.2-2.9-2.0-3.22.7-2.9-2.8-1.2-2.7-2.6-2.72.3-2.4-2.6-2.4-2.5-2.82.0-2.7
Left kidney weight1.02.86.0-1.0-1.5-2.0-2.2-2.11.5-1.6-2.4-0.1-1.9-1.6-2.01.0-1.5-1.6-1.7-1.6-2.01.5-1.5
Right kidney weight0.92.65.3-0.4-0.9-1.7-2.3-2.02.3-1.7-2.30.3-1.6-1.1-1.71.7-1.0-1.4-1.4-0.9-1.62.3-1.2
Tail length0.10.42.3-0.7-0.5-0.51.5-0.50.8-1.10.4-0.3-0.6-0.2-0.50.4-0.6-0.90.5-0.6-0.5-0.0-0.6
Length with tail1.24.48.5-1.8-2.2-2.7-0.1-2.62.4-2.9-1.7-0.7-2.7-1.7-2.51.2-2.3-2.5-0.9-2.0-2.61.0-2.2
Length without tail1.63.66.0-1.4-2.0-2.5-1.7-2.42.1-2.2-2.2-0.1-2.3-1.6-2.30.9-2.0-2.0-1.2-1.8-2.41.1-2.0
Liver weight, left0.20.21.7-0.10.1-0.00.80.2-0.10.00.90.50.20.60.2-0.60.40.21.30.3-0.1-0.50.4
Liver weight, right0.81.45.41.71.61.1-0.50.50.50.70.32.31.21.21.10.11.21.11.31.01.10.91.3
Parametrial fat weight0.20.52.8-0.10.1-0.50.8-0.61.7-1.10.21.1-0.10.2-0.20.4-0.2-0.81.1-0.2-0.50.7-0.5
Retroperitoneal fat weight0.41.34.7-0.4-0.4-1.00.1-1.32.2-2.0-0.60.3-0.7-0.5-0.71.7-0.8-1.7-0.1-0.8-0.91.7-1.3
Intraocular pressure0.60.82.0-0.7-0.9-0.8-0.2-0.90.1-0.9-0.8-1.3-1.1-1.4-1.00.5-0.8-0.8-1.0-1.4-0.80.1-1.0
Extensor digitorum longus weight1.24.616.20.7-0.4-1.4-3.0-2.31.3-1.5-2.6-2.9-1.5-2.8-1.53.8-1.0-0.5-4.0-1.2-1.32.8-1.0
Soleus weight0.61.83.2-1.1-1.2-1.4-1.5-1.50.8-1.3-1.8-0.7-1.5-1.6-1.40.8-1.3-1.3-1.7-1.6-1.40.7-1.4
Tibialis anterior weight0.82.64.8-0.9-1.3-1.7-1.0-1.91.2-1.8-1.5-2.0-1.8-2.0-1.81.8-1.3-1.3-2.2-1.7-1.71.0-1.4
Tibia length0.92.512.61.51.1-0.3-1.5-1.63.5-1.5-1.51.90.1-0.80.12.7-0.0-0.6-0.2-0.6-0.13.6-0.1
Number of licking bursts1.51.83.8-0.3-0.9-1.2-1.7-1.60.9-1.2-1.7-1.2-1.3-1.5-1.31.6-1.3-1.0-1.9-1.4-1.21.2-1.2
Food consumed during 24 hour testing period1.92.34.7-0.6-1.0-1.4-0.2-1.91.5-2.1-1.2-1.0-1.4-2.0-1.41.8-1.7-1.6-1.2-2.2-1.41.5-1.6
Times rat made contact with spout0.50.61.90.3-0.0-0.4-0.3-1.01.3-1.0-0.80.3-0.6-0.7-0.61.2-0.4-0.6-0.4-0.9-0.31.4-0.4
Mean time between licks in bursts3.04.17.6-0.2-0.9-1.9-2.7-2.62.4-2.1-2.7-0.9-1.6-2.3-1.62.8-1.6-1.6-2.5-1.7-1.82.6-1.7
Mean num. licks in bursts0.50.62.00.50.80.81.30.70.20.40.91.20.80.80.7-0.50.80.41.40.70.8-0.10.8
Std. dev. time between licks in bursts0.50.61.4-0.3-0.5-0.9-0.7-0.90.6-0.8-0.8-1.1-0.7-1.0-0.71.0-0.8-0.6-1.2-0.6-0.90.6-0.8
Water consumed over 24 hours0.40.41.90.80.50.2-1.2-0.50.9-0.3-0.81.20.0-0.20.10.9-0.00.0-0.1-0.40.31.40.1
Indifference point 0 sec0.50.94.20.20.70.71.70.80.4-0.01.61.21.01.00.9-0.50.60.22.10.50.7-0.20.6
Indifference point AUC0.80.92.3-1.0-1.2-1.30.2-1.00.2-1.1-0.4-1.5-1.1-0.7-1.30.5-1.1-0.8-0.8-0.9-1.3-0.2-1.0
Indifference point function ln k0.30.51.9-0.20.10.40.40.7-0.30.60.61.40.31.00.5-1.20.40.21.30.60.4-0.60.5
Indifference point function log k0.30.51.9-0.20.10.40.40.7-0.30.60.61.40.31.00.5-1.20.40.21.30.60.4-0.60.5
Delay discounting total patch changes 0 sec0.40.73.80.00.40.41.60.40.8-0.41.41.20.70.80.6-0.40.3-0.21.90.20.40.10.3
Delay discounting total patch changes 12 sec0.40.64.2-0.30.10.22.00.5-0.0-0.21.7-0.20.60.70.4-0.5-0.10.21.40.10.2-0.90.4
Delay discounting total patch changes 18 sec0.20.20.8-0.6-0.5-0.50.2-0.40.4-0.5-0.1-0.1-0.4-0.5-0.5-0.2-0.9-0.60.0-0.8-0.5-0.0-0.6
Delay discounting total patch changes 24 sec0.30.42.7-0.00.20.41.30.50.4-0.11.11.00.40.70.3-0.60.1-0.11.60.20.4-0.30.3
Delay discounting total patch changes 6 sec0.10.10.5-0.2-0.0-0.20.7-0.10.6-0.50.40.40.20.20.2-0.0-0.3-0.30.7-0.1-0.10.1-0.1
Delay discounting time to switch 0 sec0.10.20.6-0.10.30.60.20.5-0.60.50.2-0.40.8-0.30.8-0.4-0.00.1-0.2-0.40.5-0.70.1
Delay discounting water rate 0 sec0.30.51.80.1-0.1-0.6-0.6-0.81.3-0.9-0.60.6-0.5-0.4-0.50.8-0.4-0.60.2-0.4-0.51.4-0.5
Delay discounting water rate 12 sec0.30.44.50.30.10.0-2.1-0.20.00.3-1.21.3-0.2-0.2-0.1-0.3-0.4-0.1-0.2-0.20.10.6-0.1
Delay discounting water rate 18 sec1.21.66.41.51.61.4-0.11.00.40.90.72.51.31.41.4-0.31.20.91.71.31.50.61.3
Delay discounting water rate 24 sec1.11.53.31.31.51.5-0.11.3-0.41.40.61.81.41.21.4-0.71.31.21.11.31.50.21.3
Delay discounting water rate 6 sec0.10.20.7-0.6-0.3-0.4-0.1-0.10.0-0.2-0.20.8-0.30.1-0.2-0.8-0.4-0.40.7-0.2-0.4-0.3-0.4
Locomotor activity0.50.72.8-1.4-1.1-0.71.7-0.1-0.2-0.80.8-0.9-0.6-0.0-0.8-0.5-0.8-1.00.3-0.7-0.7-1.2-0.8
Locomotor testing distance1.11.88.1-2.1-1.6-0.82.80.2-0.9-0.61.4-1.6-0.9-0.1-1.0-1.4-1.0-1.10.7-0.9-0.9-2.3-1.0
Locomotor testing rearing0.71.15.3-1.4-0.9-0.12.30.5-1.2-0.11.5-1.8-0.2-0.4-0.4-1.0-0.7-0.60.4-0.9-0.2-2.0-0.6
Light reinforcement 10.30.52.3-0.3-0.00.21.50.6-0.10.01.40.60.21.10.2-0.90.60.21.50.70.1-0.80.4
Light reinforcement 20.60.83.2-0.20.10.51.40.9-0.30.51.30.90.31.40.3-1.20.90.41.81.00.5-0.70.7
Reaction time number correct0.20.30.8-0.2-0.5-0.4-0.7-0.60.3-0.5-0.8-0.0-0.8-0.8-0.70.4-0.7-0.5-0.5-0.9-0.30.6-0.6
Reaction time mean minus median0.10.10.4-0.5-0.5-0.20.50.0-0.4-0.10.3-0.4-0.10.1-0.2-0.3-0.1-0.40.1-0.2-0.2-0.6-0.4
Reaction time mean minus median AUC0.81.01.60.20.51.10.91.3-1.31.01.30.51.01.11.0-1.20.90.71.20.81.0-1.20.9
Reaction time num false alarms1.52.13.5-1.4-1.5-1.8-0.2-1.71.4-1.8-1.2-0.7-1.7-1.4-1.80.6-1.7-1.9-0.8-1.7-1.70.2-1.9
Reaction time num false alarms AUC1.31.83.2-1.5-1.4-1.70.2-1.61.4-1.8-1.0-0.5-1.5-1.2-1.70.4-1.5-1.8-0.5-1.5-1.70.1-1.7
Reaction time trials correct on left0.20.30.8-0.2-0.5-0.4-0.7-0.60.3-0.5-0.8-0.0-0.8-0.8-0.70.4-0.7-0.5-0.5-0.9-0.30.6-0.6
Reaction time trials on left0.20.30.8-0.3-0.5-0.3-0.6-0.50.2-0.5-0.8-0.0-0.8-0.8-0.70.2-0.7-0.5-0.4-0.9-0.30.4-0.6
Reaction time mean1.21.63.8-0.10.21.01.41.6-1.91.51.70.10.91.70.8-1.81.20.81.31.40.9-1.90.7
Reaction time mean AUC1.52.04.60.10.41.21.41.9-2.11.71.80.11.01.90.9-1.81.41.01.31.71.1-2.01.0
Median of all reaction times1.41.94.6-0.20.11.01.41.8-2.11.61.80.10.81.90.8-2.01.30.91.31.60.9-2.10.8
Reaction time omissions1.52.07.8-1.1-0.30.82.31.6-1.81.11.80.80.81.50.7-2.80.4-0.02.10.40.7-2.40.1
Reaction time false alarm rate0.60.91.8-1.2-1.0-1.30.5-1.01.0-1.2-0.5-0.5-1.0-0.6-1.10.2-1.0-1.3-0.2-0.8-1.3-0.2-1.2
Reaction time premature initiation rate0.50.61.3-0.7-0.7-1.00.8-0.91.1-1.1-0.30.0-0.5-0.6-0.60.5-0.9-1.20.0-1.0-0.90.5-1.0
Reaction time premature initiations0.71.02.0-0.7-0.9-1.10.7-1.21.3-1.4-0.5-0.1-0.9-0.9-0.90.7-1.2-1.3-0.1-1.4-1.00.7-1.2
Std. dev. reaction times1.01.42.70.10.41.01.21.4-1.61.21.60.31.11.61.0-1.41.10.71.41.10.9-1.60.7
Reaction time trials completed0.20.30.8-0.3-0.5-0.3-0.6-0.50.2-0.5-0.8-0.0-0.8-0.8-0.70.2-0.7-0.5-0.4-0.9-0.30.4-0.6
Reaction time trials AUC0.20.30.8-0.2-0.4-0.3-0.6-0.50.1-0.4-0.7-0.1-0.7-0.8-0.60.3-0.7-0.5-0.4-0.9-0.30.4-0.6
Social response proportion4.34.77.0-1.3-1.9-2.4-2.0-2.51.6-2.4-2.6-1.3-2.7-2.1-2.61.9-2.2-2.1-2.5-2.1-2.31.8-2.2
Social responses0.60.71.7-0.6-0.6-0.9-0.2-1.01.1-1.3-0.7-0.2-0.8-0.7-0.90.8-1.2-1.0-0.6-0.9-0.80.8-1.0
Social time3.64.68.0-2.2-2.6-2.7-1.2-2.30.7-2.0-2.2-1.7-2.8-1.9-2.80.7-2.5-2.4-2.2-2.2-2.70.5-2.5
Conditioned locomotion0.10.10.30.50.20.3-0.10.30.00.10.40.1-0.10.40.20.20.50.50.20.50.30.40.5
Cocaine response after cond. corrected0.40.52.5-0.1-0.0-0.4-1.6-0.71.0-0.3-1.31.0-0.1-0.5-0.10.3-0.3-0.6-0.4-0.6-0.31.0-0.5
Cocaine response after cond. not corrected0.20.32.5-0.10.20.0-1.0-0.10.50.2-0.81.60.30.10.3-0.40.1-0.20.3-0.30.10.5-0.1
Cocaine response before conditioning0.70.81.80.00.50.71.31.0-0.90.81.10.70.81.20.7-1.20.70.61.30.80.7-0.90.7
Saline control response0.30.41.2-0.2-0.5-0.41.0-0.50.5-0.80.2-1.1-0.7-0.8-0.60.8-0.5-0.5-0.4-0.9-0.40.2-0.5
Condit. Reinf. active minus inactive responses1.31.67.9-2.0-1.3-0.41.80.6-1.40.30.9-0.4-0.60.3-0.7-2.6-0.7-0.61.1-0.6-0.5-2.8-0.6
Condit. Reinf. active-inactive response ratio1.61.77.7-2.3-1.7-0.81.40.2-1.60.10.4-0.9-0.9-0.2-0.9-2.4-1.0-0.80.4-0.9-0.9-2.8-1.0
Condit. Reinf. active responses1.52.110.9-2.1-1.3-0.22.40.9-1.80.41.6-0.7-0.40.5-0.6-2.9-0.5-0.41.6-0.4-0.3-3.3-0.5
Condit. Reinf. inactive responses1.01.34.7-0.00.40.92.21.3-0.80.62.00.20.81.20.7-1.20.70.61.90.80.9-1.40.8
Condit. Reinf. lever presses0.70.94.3-1.1-0.60.11.70.9-1.40.61.2-0.30.00.6-0.0-2.0-0.00.01.00.10.0-2.1-0.0
Condit. Reinf. lever reinforcers received1.31.89.3-1.8-1.1-0.12.20.9-1.70.51.5-0.4-0.30.5-0.4-2.8-0.4-0.31.5-0.3-0.2-3.0-0.3
Pavlov. Cond. lever latency0.30.51.80.40.2-0.3-1.0-0.81.1-0.7-0.8-0.0-0.2-0.7-0.31.4-0.2-0.3-0.7-0.4-0.31.3-0.2
Pavlov. Cond. magazine entry latency0.20.20.50.50.50.5-0.50.4-0.40.70.00.00.60.30.5-0.00.60.6-0.20.60.50.10.5
Pavlov. Cond. change in total contacts0.91.25.5-1.0-0.80.21.81.0-2.30.81.3-1.5-0.20.5-0.1-1.70.10.30.30.20.0-2.30.1
Pavlov. Cond. index score0.20.31.3-0.6-0.50.00.30.5-1.20.60.3-0.5-0.10.3-0.1-1.1-0.00.1-0.00.1-0.1-1.1-0.1
Pavlov. Cond. latency score0.20.21.0-0.7-0.6-0.10.40.3-1.00.50.2-0.5-0.30.2-0.3-1.0-0.1-0.0-0.00.1-0.2-0.9-0.2
Pavlov. Cond. lever contacts0.20.31.1-0.2-0.00.40.70.7-0.90.60.80.20.20.70.3-1.10.30.30.70.40.4-1.00.3
Pavlov. Cond. magazine entry number0.50.61.3-0.8-0.8-0.80.5-0.80.7-1.2-0.2-0.5-0.9-0.8-0.80.4-0.9-0.9-0.0-1.0-0.80.0-0.8
Pavlov. Cond. intertrial magazine entries2.63.47.1-2.7-2.3-2.21.4-1.70.9-2.3-0.6-1.3-2.0-1.5-2.0-0.2-2.3-2.5-0.2-2.3-2.2-0.9-2.3
Pavlov. Cond. lever-magazine prob. diff.0.20.21.1-0.5-0.40.00.20.4-1.00.60.2-0.4-0.10.3-0.1-1.0-0.00.1-0.10.2-0.0-0.9-0.1
Pavlov. Cond. response bias0.40.51.10.20.40.70.50.9-1.00.90.80.40.60.80.6-1.00.60.70.70.60.7-0.90.6
Conditioned reinforcement - actives0.60.61.7-0.7-0.9-0.90.3-0.80.2-1.0-0.3-1.3-0.8-0.8-0.80.6-0.9-0.6-0.9-0.8-0.9-0.2-0.5
Conditioned reinforcement - inactives0.30.31.2-0.7-0.8-0.61.1-0.20.2-0.50.40.1-0.40.2-0.4-0.6-0.7-0.70.7-0.3-0.6-0.7-0.4
Conditioned locomotion1.31.63.2-1.4-1.5-1.50.1-1.30.7-1.5-0.9-1.2-1.3-1.6-1.20.3-1.8-1.4-1.0-1.7-1.50.1-1.2
Intermittent access intake day 1-15 change0.40.41.80.00.40.10.3-0.51.3-0.8-0.40.40.4-0.90.30.7-1.1-0.5-0.2-0.90.10.6-0.2
Intermittent access intake escalation0.60.62.80.40.60.1-0.3-0.71.7-0.9-0.70.60.4-0.90.41.2-0.9-0.4-0.4-0.70.21.2-0.1
Intermittent access intake escalation 21.00.94.8-0.2-0.1-0.90.2-1.32.2-1.6-0.90.4-0.3-0.8-0.41.4-0.8-1.1-0.5-0.7-0.81.2-0.7
Intermitt. access day 1 inactive lever presses2.02.25.1-2.1-2.0-1.90.9-1.51.5-1.9-0.7-0.4-1.7-0.8-1.80.0-1.4-2.2-0.3-1.4-1.9-0.2-1.6
Intermitt. access day 15 inactive lever presses1.92.19.1-2.6-1.8-0.61.70.5-1.80.10.8-0.6-0.40.1-0.5-3.0-1.1-1.01.1-1.0-0.7-2.9-0.9
Intermitt. access escalation Index0.30.31.00.2-0.3-0.4-0.9-0.4-0.10.1-0.6-0.7-0.5-0.3-0.50.70.00.1-1.00.1-0.40.9-0.0
Intermittent access day 1 total infusions0.80.91.7-0.9-1.0-1.1-0.4-1.00.3-1.0-0.8-1.3-1.1-1.3-1.10.3-1.1-0.7-1.0-1.2-1.10.1-0.7
Intermittent access day 15 total infusions0.91.02.9-0.3-0.2-0.7-0.2-1.11.4-1.5-0.9-0.9-0.3-1.7-0.31.4-1.5-0.7-1.0-1.4-0.71.0-0.6
Intermittent access terminal intake (last 3 days)1.01.13.3-1.0-0.9-1.10.3-1.10.6-1.4-0.6-1.2-0.7-1.7-0.70.4-1.7-1.0-0.8-1.8-1.1-0.0-0.8
Intermittent access total infusions1.21.32.7-0.8-0.9-1.2-0.1-1.31.2-1.6-0.9-1.2-1.1-1.7-1.11.2-1.4-1.1-1.1-1.4-1.20.8-0.9
Intermittent access day 1 locomotion2.93.05.5-1.7-1.6-2.0-0.1-2.01.6-2.3-1.5-1.5-1.5-2.2-1.51.1-2.2-1.9-1.5-2.4-2.00.7-1.6
Intermittent access day 15 total locomotion1.21.33.7-0.9-0.4-0.90.2-1.31.7-1.9-0.7-0.8-0.0-1.60.01.2-1.7-1.4-0.8-1.6-0.80.9-1.1
Intermittent access total locomotion3.43.98.4-2.1-1.6-2.10.2-2.32.2-2.9-1.6-1.5-1.3-2.5-1.31.3-2.7-2.5-1.5-2.7-2.00.9-2.1
Intermittent access standard deviation0.40.42.7-0.4-0.0-0.31.7-0.31.0-1.00.50.30.3-0.10.30.2-0.8-0.70.8-0.5-0.2-0.2-0.4
Cocaine induced anxiety0.40.52.30.10.20.1-1.4-0.41.1-0.3-1.11.5-0.1-0.4-0.10.1-0.6-0.50.1-0.40.21.0-0.5
Post-drug Anxiety2.02.25.3-0.9-1.0-1.2-2.1-1.71.5-1.4-2.30.0-1.4-1.7-1.40.9-1.7-1.7-1.4-1.7-1.11.3-1.8
Baseline Anxiety0.30.31.0-0.4-0.8-0.8-0.1-0.5-0.3-0.3-0.3-1.0-0.6-0.3-0.60.3-0.1-0.3-0.8-0.3-0.9-0.1-0.5
Lifetime Intake1.21.32.5-1.1-1.2-1.30.3-1.20.9-1.6-0.7-1.1-1.4-1.4-1.40.6-1.4-1.2-0.7-1.5-1.30.3-0.9
Incentive Sensitization - Responses0.50.51.7-1.3-0.7-0.41.0-0.1-0.2-0.50.3-0.80.1-0.60.1-0.8-0.9-0.80.0-1.0-0.5-1.0-0.7
Incentive Sensitization - Breakpoint0.40.41.4-1.2-0.6-0.21.10.0-0.3-0.40.4-0.70.4-0.50.3-0.8-0.8-0.70.1-0.9-0.3-1.0-0.6
Progressive ratio test 1 active lever presses0.80.92.0-1.4-1.4-1.20.9-0.5-0.5-0.70.1-1.4-1.2-0.7-1.2-0.4-0.7-0.7-0.3-0.9-1.3-0.9-0.5
Progressive ratio test 1 breakpoint1.21.33.1-1.8-1.6-1.30.9-0.6-0.5-0.9-0.0-1.7-1.4-1.0-1.4-0.6-1.1-1.0-0.4-1.2-1.4-1.1-0.8
Progressive ratio test 1 inactive lever presses0.90.94.3-1.5-1.3-0.92.1-0.40.3-1.00.8-0.7-0.9-0.2-0.9-0.6-0.7-1.00.7-0.8-1.0-1.1-0.5
Progressive ratio test 2 active lever presses0.70.71.9-1.4-1.0-1.10.7-0.70.4-1.2-0.2-1.1-0.5-0.9-0.60.1-0.9-1.1-0.4-1.1-1.1-0.3-0.9
Progressive ratio test 2 breakpoint0.70.81.9-1.4-1.0-1.10.9-0.80.5-1.3-0.2-1.1-0.5-1.0-0.50.3-1.0-1.2-0.4-1.1-1.1-0.1-0.9
Progressive ratio test 2 inactive lever presses1.51.84.2-1.7-1.6-1.60.9-1.31.3-2.1-0.5-1.0-1.3-1.0-1.40.6-1.7-1.9-0.5-1.4-1.60.1-1.5
Total sessions with >9 infusions0.50.61.6-0.5-0.9-1.10.5-0.70.3-0.9-0.1-1.2-1.3-0.4-1.20.7-0.4-0.5-0.5-0.2-1.10.2-0.2
Short access day 1 total inactive lever presses0.50.61.6-1.1-1.1-0.6-0.2-0.3-0.4-0.4-0.5-0.4-1.0-0.7-1.1-0.7-1.3-1.0-0.2-1.1-0.6-0.4-0.9
Short access day 10 total inactive lever presses2.42.65.2-1.6-1.7-2.00.3-1.92.1-2.3-1.1-0.3-2.1-1.0-2.20.9-1.6-2.1-0.7-1.5-2.00.7-1.7
Short access day 1 total infusions0.50.51.7-0.7-1.1-0.51.2-0.1-0.4-0.50.6-1.0-1.3-0.2-1.3-0.2-0.5-0.40.2-0.7-0.5-0.7-0.1
Short access day 10 total infusions1.51.73.4-1.8-1.6-1.50.8-1.20.7-1.6-0.5-1.3-1.5-1.5-1.40.0-1.7-1.4-0.4-1.9-1.5-0.4-1.2
Short access total infusions1.21.33.1-1.4-1.6-1.31.1-0.80.2-1.3-0.0-1.2-1.8-1.0-1.7-0.1-1.3-1.0-0.1-1.5-1.3-0.6-0.8
Short access day 1 locomotion0.90.92.5-1.4-1.2-0.81.1-0.60.2-1.10.0-0.8-0.9-0.8-0.9-0.4-1.6-1.20.0-1.5-0.8-0.6-1.0
Short access day 10 total locomotion6.47.015.3-3.4-2.7-2.91.3-2.72.6-3.9-1.5-2.4-2.3-2.6-2.41.4-3.3-3.6-1.8-3.3-2.90.1-3.0
Short access total locomotion5.65.79.8-3.0-2.8-2.80.8-2.41.7-3.1-1.4-2.5-2.5-2.3-2.61.0-3.0-2.9-1.9-2.8-2.80.0-2.6
Compulsive drug intake0.80.81.81.21.21.1-1.00.70.10.9-0.11.31.10.71.10.20.90.70.30.91.21.00.5
One hour access (0.3 mA shock)0.70.92.4-0.7-0.3-0.8-0.4-1.01.1-1.3-1.1-0.6-0.2-1.5-0.21.0-1.2-1.0-1.0-1.3-0.70.7-0.9
One hour access (shock baseline)2.42.85.4-1.4-1.3-1.8-0.3-2.01.6-2.3-1.4-1.8-1.4-2.3-1.41.5-2.1-1.8-1.7-2.1-1.80.7-1.5
Number of responses in last shaping day4.84.87.7-2.0-2.5-2.8-0.6-2.61.9-2.5-2.1-1.2-2.6-2.4-2.61.0-2.5-2.6-1.5-2.5-2.70.9-2.4
Context. condit. distance diff. score0.40.51.80.90.5-0.0-1.2-0.60.9-0.3-0.8-0.30.1-0.80.11.3-0.10.2-0.7-0.20.01.30.1
Locomotion velocity, session 10.20.21.1-0.00.40.51.00.4-0.10.10.80.40.20.40.3-0.40.30.10.90.10.5-0.50.3
Locomotion distance, session 10.10.10.50.10.40.40.70.30.3-0.10.40.30.40.30.40.0-0.1-0.10.50.30.40.10.1
Locomotion velocity, session 21.82.13.40.51.21.61.01.8-1.41.61.71.01.51.71.5-1.61.41.21.81.51.6-1.51.2
Locomotion distance, session 20.30.51.50.20.60.61.20.7-0.30.41.20.10.90.80.7-0.40.60.50.90.60.6-0.70.6
Locomotion velocity, session 30.20.21.70.40.40.1-0.8-0.00.80.2-0.41.30.20.50.20.20.50.10.20.60.10.60.4
Locomotion distance, session 30.20.32.3-0.0-0.2-0.4-1.5-0.40.30.1-1.00.3-0.3-0.3-0.30.1-0.0-0.1-0.6-0.0-0.40.4-0.1
Stereotopy head waving bouts, day 31.51.84.01.51.51.5-0.11.20.11.20.82.01.51.31.5-0.41.71.51.61.41.50.51.7
Stereotopy head waving duration, day 30.91.11.91.31.21.30.21.0-0.10.90.90.91.30.91.4-0.11.21.31.11.11.30.31.3
Locomotion velocity, session 70.70.82.21.51.40.8-0.50.20.80.3-0.01.20.90.40.90.90.90.80.40.70.91.21.0
Locomotion distance, session 70.20.20.70.70.80.5-0.40.20.10.50.10.10.60.00.50.20.70.70.10.20.50.20.6
Stereotopy head waving bouts, day 70.91.12.60.50.61.0-0.61.2-1.21.30.61.20.81.60.9-1.11.01.11.01.40.9-0.51.0
Stereotopy head waving duration, day 72.02.44.71.41.41.7-0.31.7-1.41.81.21.31.62.21.7-0.91.71.81.32.21.7-0.41.7
Locomotion velocity, session 80.91.14.80.40.1-0.70.3-1.42.2-1.6-0.5-0.3-0.5-1.1-0.52.0-0.6-0.9-0.4-0.9-0.61.6-0.6
Locomotion distance, session 80.30.41.20.91.00.80.30.5-0.00.40.7-0.11.10.40.90.30.50.80.50.70.80.10.8
Degree of sensitization distance0.30.31.0-0.1-0.1-0.30.6-0.50.6-0.80.2-1.0-0.4-0.7-0.50.8-0.5-0.4-0.3-0.6-0.30.1-0.5
Degree of sensitization stereotypy0.80.92.10.60.60.9-0.61.1-1.31.30.50.80.81.50.8-0.90.91.00.61.30.9-0.50.9
Condit. Reinf. active minus inactive responses0.91.02.6-1.6-1.4-0.71.0-0.0-1.3-0.10.3-1.5-1.1-0.5-0.8-1.2-0.9-0.7-0.0-0.8-0.8-1.4-0.9
Condit. Reinf. active-inactive response ratio0.60.73.1-1.1-0.9-0.20.40.4-1.80.60.3-1.4-0.4-0.3-0.1-1.4-0.5-0.0-0.2-0.4-0.3-1.6-0.4
Condit. Reinf. active responses0.50.62.5-1.3-1.0-0.41.60.2-0.8-0.20.8-1.1-0.6-0.2-0.5-1.1-0.5-0.60.5-0.6-0.5-1.1-0.5
Condit. Reinf. inactive responses0.30.31.70.20.40.31.30.20.9-0.20.80.90.20.40.1-0.00.5-0.11.20.10.30.40.4
Incentive salience index mean0.70.92.6-1.6-1.2-0.41.30.3-1.50.20.6-1.1-0.7-0.1-0.4-1.6-0.6-0.50.4-0.5-0.5-1.6-0.6
Condit. Reinf. lever presses0.20.31.5-0.40.00.31.20.5-0.50.30.7-0.00.40.50.4-0.80.20.10.80.30.2-0.40.2
Time in familiar zone, hab. session 10.60.63.20.80.4-0.10.1-0.81.1-0.8-0.3-0.90.1-1.00.11.8-0.3-0.2-0.8-0.8-0.01.3-0.2
Time in novel zone, hab. session 10.40.42.4-0.6-0.30.0-0.70.6-1.00.8-0.00.7-0.20.8-0.2-1.50.30.30.60.8-0.0-1.00.3
Total zone transitions, hab. session 10.60.93.40.50.2-0.4-1.2-1.11.2-0.9-1.2-0.5-0.0-1.0-0.21.8-0.6-0.5-1.3-0.5-0.31.7-0.5
Total locomotion distance, hab. session 10.20.30.9-0.7-0.5-0.60.0-0.60.8-0.7-0.50.1-0.3-0.4-0.40.1-0.8-0.90.1-0.5-0.50.3-0.8
Locomotion velocity, hab. session 10.40.51.4-0.9-0.7-0.80.1-0.81.0-1.0-0.5-0.2-0.5-0.6-0.60.3-1.0-1.2-0.1-0.7-0.80.4-1.0
Time in familiar zone, hab. session 20.91.05.30.60.2-0.50.0-1.21.8-1.4-0.5-0.9-0.4-1.2-0.42.3-0.5-0.5-0.9-0.8-0.41.5-0.4
Time in novel zone, hab. session 21.41.46.5-0.4-0.00.7-0.41.4-1.71.70.51.40.61.60.6-2.60.80.81.31.30.6-1.50.7
Total zone transitions, hab. session 20.20.31.10.80.70.4-0.7-0.0-0.20.1-0.1-0.70.7-0.30.41.00.20.4-0.70.10.50.90.2
Total locomotion distance, hab. session 20.20.21.00.70.60.3-0.6-0.00.00.0-0.0-0.40.7-0.10.50.80.30.3-0.20.20.31.00.2
Locomotion velocity, hab. session 20.20.31.30.80.60.3-0.6-0.10.2-0.1-0.1-0.30.8-0.20.61.00.20.3-0.20.10.31.20.2
Novel to familiar place preference ratio0.30.30.7-0.8-0.7-0.50.1-0.40.5-0.6-0.30.1-0.8-0.5-0.7-0.3-0.8-0.80.1-0.8-0.5-0.2-0.8
Novelty place preference0.20.20.5-0.7-0.5-0.3-0.0-0.20.3-0.3-0.20.3-0.5-0.3-0.5-0.5-0.6-0.60.2-0.6-0.3-0.3-0.6
Time in novel zone, NPP test0.10.10.3-0.5-0.3-0.1-0.2-0.10.3-0.1-0.10.5-0.4-0.1-0.3-0.5-0.4-0.50.4-0.4-0.1-0.2-0.4
Total zone transitions, NPP test0.50.72.01.21.41.1-0.40.6-0.20.60.50.31.40.31.20.50.70.90.30.61.20.50.9
Total locomotion distance, NPP test0.10.20.60.30.50.5-0.20.30.20.20.20.60.60.30.5-0.10.20.20.80.30.50.30.3
Locomotion velocity, NPP test0.00.00.10.00.30.1-0.2-0.10.3-0.2-0.10.10.4-0.20.20.2-0.1-0.10.2-0.10.10.4-0.0
Pavlov. Cond. lever latency1.11.44.22.11.61.4-0.80.9-0.71.20.30.31.20.71.00.81.61.7-0.21.31.40.81.5
Pavlov. Cond. magazine entry latency0.71.06.4-1.2-0.6-0.22.50.40.0-0.21.30.50.00.8-0.1-1.5-0.2-0.51.8-0.0-0.2-1.4-0.1
Pavlov. Cond. change in total contacts0.80.93.4-1.6-1.1-0.71.80.0-0.7-0.40.8-0.8-0.70.1-0.6-1.3-0.7-0.70.8-0.5-0.8-1.6-0.6
Pavlov. Cond. index score0.70.93.3-1.7-1.2-0.91.8-0.20.3-0.80.6-0.2-0.70.1-0.8-1.2-1.0-1.11.0-0.5-0.9-1.2-0.8
Pavlov. Cond. latency score0.70.93.0-1.7-1.2-1.01.5-0.40.5-1.00.3-0.3-0.8-0.1-0.9-0.9-1.1-1.30.7-0.7-1.0-1.0-1.0
Pavlov. Cond. lever contacts1.41.74.1-2.0-1.8-1.60.8-1.10.6-1.3-0.5-0.9-1.5-0.9-1.4-0.4-1.6-1.7-0.3-1.3-1.6-0.7-1.6
Pavlov. Cond. magazine entry number1.41.89.10.80.1-0.5-3.0-1.30.8-0.5-2.1-0.6-0.6-1.5-0.52.1-0.6-0.3-2.4-0.7-0.42.0-0.7
Pavlov. Cond. intertrial magazine entries0.91.12.9-0.5-0.9-1.00.2-1.10.5-1.2-0.5-1.7-1.1-1.2-0.91.2-1.1-1.2-1.1-1.1-0.90.9-1.3
Pavlov. Cond. lever-magazine prob. diff.0.91.13.8-2.0-1.3-1.01.7-0.20.1-0.70.4-0.2-0.80.0-0.9-1.4-1.1-1.30.9-0.6-1.0-1.4-1.0
Pavlov. Cond. response bias0.91.15.4-1.6-0.8-0.42.30.4-0.2-0.11.10.5-0.20.7-0.2-2.0-0.3-0.71.9-0.1-0.4-1.8-0.2
Bone: apparent density0.30.62.7-0.8-0.3-0.10.80.30.4-0.00.41.6-0.31.0-0.1-1.40.0-0.41.70.3-0.1-0.80.0
Bone surface1.32.37.0-2.6-2.2-1.70.7-1.00.6-1.1-0.60.5-1.8-0.5-1.7-1.8-1.7-2.10.7-1.6-1.8-1.1-1.7
Bone volume0.71.23.6-1.9-1.4-1.00.8-0.50.7-0.8-0.20.9-1.2-0.1-1.0-1.5-1.1-1.51.2-1.1-1.1-0.9-1.1
Bone: connectivity density0.60.94.7-1.4-0.8-0.31.10.5-0.50.20.71.0-0.51.1-0.3-2.2-0.2-0.51.60.3-0.3-1.7-0.2
Bone: cortical apparent density7.69.915.73.33.63.80.83.5-2.13.62.72.44.03.43.8-1.33.53.72.53.73.8-0.63.6
Bone: cortical area0.60.92.2-1.4-1.0-1.0-0.2-0.81.1-0.8-0.71.1-0.6-0.4-0.9-0.9-1.1-1.50.5-1.2-0.9-0.1-1.1
Bone: cortical porosity6.97.515.7-4.0-3.5-3.31.0-2.61.7-2.9-1.7-1.0-3.2-2.6-3.3-0.8-3.2-3.6-0.6-3.8-3.3-0.9-3.2
Bone: cortical porosity6.36.813.2-3.3-3.0-3.10.2-2.82.3-2.9-2.1-0.6-3.0-2.7-3.1-0.1-3.1-3.4-1.0-3.6-3.1-0.1-3.1
Bone: cortical thickness1.32.211.41.41.81.5-1.21.00.71.20.13.41.81.91.5-0.51.31.01.51.61.50.81.3
Bone: cortical thickness2.83.37.41.01.51.8-0.72.0-1.62.41.02.71.92.41.9-2.31.71.81.81.81.7-1.01.8
Bone: cortical tissue density7.59.715.43.23.53.70.83.5-2.33.62.82.23.93.43.8-1.43.53.72.53.63.7-0.73.5
Bone: elastic displacement0.20.21.2-0.00.10.1-0.50.3-0.10.5-0.11.10.11.00.4-0.60.30.20.40.90.1-0.40.3
Bone: elastic work0.20.30.9-0.9-0.6-0.50.2-0.20.5-0.3-0.10.9-0.50.4-0.4-0.7-0.4-0.70.6-0.1-0.6-0.6-0.5
Bone: endosteal estimation4.29.018.6-4.3-4.1-3.50.8-2.50.4-2.7-1.5-3.0-3.4-3.4-3.5-1.0-3.4-3.5-1.4-4.1-3.6-1.4-3.5
Bone: endosteal perimeter6.814.027.7-4.9-4.9-4.40.6-3.51.1-3.6-2.3-3.4-4.4-4.3-4.4-0.4-4.4-4.5-2.1-5.3-4.4-1.0-4.5
Bone: final force0.30.53.8-0.20.30.30.50.20.70.10.42.00.60.70.2-1.00.3-0.21.6-0.10.3-0.20.2
Bone: final moment0.30.64.2-0.20.30.30.60.30.60.20.52.00.60.80.3-1.10.3-0.21.7-0.10.3-0.30.3
Bone: marrow area4.18.718.0-4.2-4.0-3.50.8-2.50.5-2.7-1.5-2.9-3.4-3.3-3.5-0.9-3.4-3.5-1.4-4.0-3.6-1.3-3.4
Bone: maximum diameter1.32.46.1-2.5-2.1-1.70.4-1.20.5-1.2-0.7-0.4-1.6-1.5-1.6-1.3-1.9-2.10.1-2.5-1.7-0.8-1.9
Bone: maximum force0.61.02.7-1.2-0.9-1.10.1-1.11.6-1.2-0.70.8-0.8-0.7-1.1-0.1-1.1-1.60.3-1.3-1.10.4-1.1
Bone: maximum moment0.50.82.1-1.1-0.9-0.90.3-0.91.4-1.0-0.61.0-0.7-0.6-1.0-0.4-0.9-1.40.5-1.1-0.90.3-1.0
Bone: minimum diameter5.510.219.9-4.5-4.1-3.80.5-3.01.6-3.3-2.0-2.0-3.5-3.3-3.9-0.6-3.9-4.2-1.4-4.3-3.9-0.9-3.9
Bone: periosteal estimation2.65.313.3-3.6-3.1-2.70.4-1.90.9-2.1-1.3-1.0-2.5-2.2-2.7-1.4-2.8-3.1-0.4-3.2-2.8-1.1-2.8
Bone: periosteal perimeter3.66.012.2-3.5-3.2-2.9-0.2-2.31.0-2.1-1.9-1.2-2.9-2.7-2.9-0.9-2.9-3.1-1.2-3.5-2.9-0.7-2.9
Bone: post-yield work6.08.211.5-2.6-3.0-3.4-1.3-3.32.3-3.1-2.9-1.9-3.2-3.2-3.21.6-3.3-3.4-2.7-3.1-3.31.5-3.4
Bone: stiffness0.10.21.10.10.1-0.20.3-0.51.1-0.6-0.10.10.2-0.5-0.30.6-0.2-0.50.1-0.6-0.10.7-0.3
Bone: tissue strength0.90.93.91.61.10.6-0.10.01.4-0.10.01.00.50.50.61.50.70.40.30.90.72.00.6
Bone: trabecular number0.50.82.9-1.3-0.8-0.41.30.30.2-0.20.61.2-0.60.8-0.4-1.7-0.2-0.71.7-0.1-0.4-1.3-0.3
Bone: trabecular spacing0.50.63.30.60.3-0.1-0.3-0.70.7-0.6-0.5-1.30.1-1.0-0.01.8-0.3-0.1-1.4-0.5-0.11.4-0.3
Bone: trabecular thickness0.91.12.2-1.5-1.4-1.3-0.3-1.00.7-0.9-0.90.4-1.3-0.7-1.2-0.7-1.2-1.40.2-1.1-1.3-0.3-1.2
Bone: trabecular tissue density0.81.22.61.31.41.30.21.00.00.90.61.61.41.21.4-0.21.11.01.21.31.30.41.1
Breakpoint value in progressive ratio session0.40.41.7-0.9-0.8-0.11.20.3-0.9-0.00.7-1.3-0.6-0.2-0.6-0.6-0.2-0.10.1-0.6-0.1-1.2-0.1
Distance traveled before self-admin0.50.51.5-1.1-1.0-0.40.2-0.2-0.8-0.0-0.3-1.1-0.6-0.9-0.6-0.6-0.8-0.5-0.6-1.2-0.5-1.0-0.5
Distance traveled after self-admin0.40.51.5-0.7-0.7-0.7-0.8-0.50.1-0.2-0.8-0.9-0.2-0.6-0.20.3-0.7-0.9-1.2-0.5-0.70.2-1.1
Delta time in closed arm before/after self-admin2.02.09.61.41.2-0.0-1.2-1.23.1-1.3-1.41.30.3-0.80.32.6-0.2-0.7-0.6-0.40.23.0-0.5
Delta time in open arm before/after self-admin0.90.83.3-0.2-0.4-0.11.20.6-1.80.71.3-1.6-0.30.6-0.3-0.71.01.00.20.8-0.3-1.40.9
Diff in mean of infusions in LGA sessions0.50.61.4-0.8-1.0-1.00.5-0.80.4-1.0-0.3-1.2-0.9-0.8-0.90.5-0.7-0.8-0.6-1.0-1.0-0.0-0.8
Extinction: sum of active levers before priming0.10.10.70.2-0.1-0.10.4-0.30.6-0.60.0-0.5-0.4-0.2-0.40.9-0.3-0.1-0.4-0.1-0.10.10.1
Active lever presses in extinction session 62.72.65.0-2.0-2.2-2.00.6-1.50.4-1.5-0.8-1.8-2.2-1.5-2.20.0-1.5-1.7-1.0-1.9-2.1-0.7-1.5
Delta distance traveled before/after self-admin0.30.41.20.70.70.3-0.50.10.70.1-0.10.70.80.60.80.60.6-0.00.00.90.31.1-0.0
Delta ambulatory time before/after self-admin0.50.52.60.70.5-0.2-0.2-0.41.6-0.5-0.20.70.40.50.41.30.4-0.5-0.00.9-0.11.6-0.3
Time in closed arm before self-admin3.43.96.42.52.42.50.52.0-0.92.01.72.02.22.22.2-0.22.42.11.82.22.50.42.2
Time in closed arm after self-admin4.04.111.33.43.22.4-0.61.01.60.80.52.52.61.32.62.11.81.40.91.82.52.71.5
Time in open arm before self-admin3.43.68.8-1.1-1.4-1.8-2.7-2.01.6-1.4-3.0-0.9-1.9-2.4-1.91.2-2.0-1.8-2.6-1.9-1.71.3-2.0
Time in open arm after self-admin5.05.511.3-2.6-3.1-3.3-0.5-2.40.3-2.0-1.8-2.9-3.2-2.3-3.20.4-2.1-2.0-2.4-2.2-3.4-0.5-2.1
Sum of active levers in priming session hrs 5-61.51.55.8-0.00.41.40.71.7-2.41.51.4-1.20.80.60.8-1.30.81.40.30.71.3-1.81.1
Time to tail flick, vehicle, before self-admin0.90.92.30.41.01.1-1.20.9-0.91.5-0.10.91.40.21.4-1.20.90.80.50.51.0-0.40.7
Time to tail flick, vehicle, after self-admin0.20.21.9-0.3-0.20.01.40.2-0.1-0.30.8-0.4-0.10.2-0.1-0.10.0-0.30.80.00.0-0.4-0.2
Time to tail flick, test, before self-admin0.40.42.30.40.40.3-1.5-0.1-0.20.1-0.8-0.90.4-0.60.41.0-0.10.2-1.3-0.20.30.6-0.2
Time to tail flick, test, after self-admin0.20.20.7-0.6-0.4-0.0-0.0-0.0-0.60.1-0.0-0.4-0.3-0.6-0.3-0.7-0.30.00.0-0.8-0.1-0.9-0.2
Delta time to tail flick, vehicle, before/after SA0.80.85.3-1.0-1.0-0.92.3-0.30.0-1.11.1-0.9-0.80.5-0.8-0.0-0.6-0.70.70.0-0.9-0.8-0.5
Delta time to tail flick, test, before/after SA0.80.73.2-1.0-0.9-0.31.40.2-1.00.20.9-0.3-0.7-0.0-0.7-1.7-0.30.11.0-0.5-0.4-1.80.2
Ambulatory time before self-admin0.50.61.5-1.1-1.0-0.50.2-0.2-0.8-0.1-0.3-1.0-0.7-0.9-0.7-0.7-0.8-0.5-0.7-1.2-0.6-1.1-0.6
Ambulatory time after self-admin0.40.41.3-0.7-0.7-0.7-0.4-0.60.5-0.6-0.7-0.3-0.4-0.5-0.40.2-0.7-1.1-0.8-0.7-0.70.4-1.1
Total heroin consumption0.80.94.0-1.1-0.60.60.81.0-1.80.80.8-0.70.0-0.10.0-2.0-0.40.30.4-0.80.5-2.00.2
Area under the delay curve0.20.30.8-0.4-0.6-0.5-0.3-0.5-0.1-0.2-0.5-0.7-0.5-0.9-0.40.1-0.5-0.3-0.6-0.9-0.50.0-0.5
Delay disc. indifference point, 0s delay0.20.31.40.00.00.20.20.5-1.20.70.6-0.70.20.20.3-0.50.40.70.10.30.2-0.70.4
Delay disc. indifference point, 16s delay0.80.92.0-0.4-0.6-0.9-1.4-1.10.7-0.6-1.4-0.4-0.9-1.4-0.80.6-0.8-0.8-1.1-1.2-0.90.7-0.8
Delay disc. indifference point, 2s delay0.60.72.8-1.1-0.7-0.01.50.6-1.00.31.0-0.3-0.10.60.1-1.5-0.1-0.11.00.3-0.1-1.7-0.2
Delay disc. indifference point, 24s delay0.60.61.6-0.8-0.9-0.70.1-0.7-0.2-0.6-0.5-1.1-0.9-1.1-0.80.2-1.0-0.7-0.8-1.3-0.7-0.2-0.9
Delay disc. indifference point, 4s delay0.10.10.5-0.1-0.10.2-0.30.2-0.70.5-0.1-0.30.1-0.60.1-0.6-0.00.3-0.1-0.60.1-0.60.1
Delay disc. indifference point, 8s delay0.20.30.60.50.40.60.20.6-0.60.70.40.40.50.40.6-0.40.80.70.30.30.6-0.20.6
Delay discount exponential model param0.40.41.30.60.70.60.20.7-0.10.50.60.90.71.10.6-0.20.70.60.71.10.7-0.00.7
Delay discount hyperbolic model param0.20.20.70.50.60.4-0.10.30.20.20.20.70.50.80.40.10.40.30.30.90.40.30.5
Fecal boli incidents, locomotor time 10.10.10.40.50.60.5-0.00.10.5-0.0-0.00.60.4-0.00.40.50.20.1-0.1-0.10.50.40.1
Change in fecal boli incidents, locomotor task0.20.20.5-0.5-0.6-0.6-0.3-0.40.1-0.3-0.4-0.4-0.7-0.4-0.7-0.0-0.2-0.3-0.3-0.4-0.7-0.0-0.5
Time >=10cm from walls, locomotor time 10.50.51.90.20.20.5-1.20.7-1.41.4-0.20.40.50.50.5-1.10.40.8-0.10.70.4-0.50.4
Bouts of movement, locomotor time 10.20.31.50.70.60.5-1.20.3-0.10.5-0.40.60.60.30.50.20.20.2-0.20.60.60.30.3
Total resting periods, locomotor time 10.20.32.50.60.50.4-1.60.00.10.4-0.70.70.30.10.30.20.10.0-0.40.40.40.50.1
Rest time, locomotor task time 11.21.33.00.60.81.1-0.41.4-1.11.50.81.01.01.60.9-1.11.51.20.91.71.1-0.91.4
Distance moved, locomotor task time 11.51.63.0-0.9-1.2-1.40.0-1.51.0-1.5-1.0-1.2-1.4-1.6-1.30.9-1.5-1.2-1.1-1.7-1.40.7-1.4
Vertical activity count, locomotor time 10.90.91.7-0.9-1.0-1.1-0.2-1.00.6-0.9-1.0-0.8-1.0-1.3-0.90.3-1.2-1.1-0.8-1.3-1.10.5-1.2
Time >=10cm from walls, locomotor time 20.30.31.3-0.8-0.6-0.3-0.2-0.2-0.50.1-0.40.1-0.2-0.6-0.2-0.9-0.9-0.60.0-1.1-0.3-0.5-0.8
Bouts of movement, locomotor time 20.20.20.7-0.1-0.10.00.10.3-0.30.40.10.8-0.10.7-0.0-0.80.30.20.40.7-0.0-0.50.5
Total resting periods, locomotor time 20.20.31.00.30.10.2-0.30.4-0.20.6-0.11.00.10.80.1-0.70.50.50.30.90.2-0.20.7
Rest time, locomotor task time 20.30.42.10.60.1-0.3-1.4-0.50.6-0.0-0.90.2-0.4-0.0-0.40.70.50.2-0.80.5-0.31.00.3
Distance moved, locomotor task time 20.10.20.6-0.4-0.4-0.30.4-0.2-0.1-0.2-0.1-0.5-0.2-0.6-0.2-0.2-0.7-0.3-0.2-0.8-0.3-0.3-0.5
Vertical activity count, locomotor time 20.20.21.0-0.6-0.30.11.00.4-0.60.30.6-0.10.10.20.2-0.9-0.2-0.20.7-0.10.1-0.9-0.2
Weight adjusted by age0.50.61.3-1.0-0.9-0.5-0.4-0.3-0.90.1-0.7-1.1-0.6-1.0-0.6-0.7-1.2-0.4-0.9-1.0-0.5-0.6-0.7
Seeking ratio, delayed vs. immediate footshock2.63.05.2-1.7-1.7-1.8-0.7-1.71.0-1.9-1.5-2.3-1.7-2.2-1.81.3-2.0-1.9-2.2-1.9-1.70.2-1.9
Locomotion in novel chamber0.91.24.4-1.6-1.1-0.40.2-0.1-1.3-0.0-0.2-1.3-0.1-1.5-0.0-1.4-1.6-0.7-0.4-2.1-0.5-1.6-1.3
Locomotion in novel chamber post-restriction0.20.30.6-0.7-0.5-0.60.7-0.50.6-0.80.00.2-0.4-0.3-0.4-0.3-0.4-0.60.4-0.7-0.6-0.3-0.3
Progressive ratio0.20.20.70.20.40.50.80.4-0.30.20.6-0.10.7-0.20.7-0.3-0.00.30.3-0.40.4-0.50.3
Food seeking constrained by brief footshock0.40.52.2-0.9-0.6-0.50.8-0.50.5-0.90.2-1.5-0.2-0.5-0.30.8-0.6-1.0-0.5-0.5-0.50.2-0.9
Seeking ratio, punishment vs. effort0.40.51.1-0.7-0.9-1.0-0.3-0.80.5-0.7-0.5-0.8-1.0-0.2-1.00.6-0.3-0.8-0.70.0-1.00.5-0.8
Run reversals in cocaine runway, females1.41.44.6-0.6-0.6-1.0-1.9-1.30.9-0.9-2.2-0.0-0.4-1.5-0.40.5-1.4-1.4-1.6-1.3-0.90.8-1.6
Run reversals in cocaine runway, males0.50.51.8-0.8-0.6-0.4-0.0-0.50.6-0.7-0.70.4-0.4-0.8-0.4-0.1-1.1-1.0-0.2-1.3-0.40.4-0.8
Latency to leave start box in cocaine runway0.40.41.50.50.2-0.4-1.1-0.61.2-0.4-0.90.2-0.4-0.4-0.41.20.4-0.3-0.60.3-0.31.1-0.2
Latency to leave start box in cocaine runway, F1.41.64.70.2-0.4-1.1-2.2-1.41.8-0.8-2.1-0.2-1.1-1.2-1.11.7-0.2-0.9-1.6-0.1-1.01.7-1.0
Latency to leave start box in cocaine runway, M1.71.62.70.91.31.51.41.4-0.91.01.70.91.51.41.4-0.71.41.31.41.01.4-1.11.4
Cd content in liver1.41.63.41.51.41.6-0.21.3-1.41.50.9-0.51.50.71.50.11.41.9-0.01.31.6-0.21.4
Co content in liver0.70.94.9-0.9-0.7-0.10.70.6-2.20.60.7-2.2-0.2-0.0-0.1-0.9-0.00.4-0.60.1-0.2-1.8-0.1
Cu content in liver0.40.52.5-1.0-0.9-0.20.50.4-1.60.20.5-0.9-0.30.2-0.4-1.2-0.5-0.20.2-0.3-0.3-1.4-0.4
Fe content in liver3.74.37.62.72.52.6-0.42.1-1.32.31.41.52.81.82.7-0.42.42.51.62.22.60.32.4
K content in liver2.32.37.1-0.40.21.11.01.9-2.61.91.70.50.91.80.9-2.70.91.21.51.11.0-2.51.0
Mg content in liver7.37.515.91.11.93.01.43.5-4.03.43.11.12.73.12.7-3.12.52.92.52.42.8-3.02.6
Mn content in liver3.94.411.71.31.72.01.72.3-1.31.92.52.51.83.41.9-1.82.01.82.92.72.0-1.22.1
Na content in liver1.71.86.5-0.50.00.82.11.5-2.21.41.9-0.50.71.00.7-2.10.80.91.30.80.7-2.50.8
Rb content in liver4.35.412.41.11.52.50.83.1-3.53.02.80.22.32.42.3-2.42.32.61.72.22.4-2.42.3
Se content in liver0.50.51.51.20.80.7-1.10.4-0.40.7-0.1-0.20.80.40.80.80.71.0-0.70.80.70.70.7
Sr content in liver0.90.84.0-0.6-0.6-0.7-2.0-0.80.1-0.3-1.70.1-0.7-1.1-0.70.0-0.8-0.6-1.1-1.0-0.70.5-0.8
Zn content in liver0.40.51.8-0.20.20.70.40.8-1.30.90.6-0.00.60.40.6-1.20.50.60.6-0.00.6-1.20.4