Vti1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability ENSRNOG00000042786 0.06 0.05 4.4e-03 0.05 0.03 0.04 0.04 1.7e-03 7.2e-03 2.1e-03 1.9e-03
2 Brain gene expression ENSRNOG00000042786 0.07 0.05 2.2e-05 0.02 0.04 0.04 0.03 1.1e-02 7.0e-05 1.2e-04 1.0e-03
3 Brain mRNA stability ENSRNOG00000042786 0.15 0.08 6.9e-12 0.06 0.11 0.1 0.1 5.0e-06 2.5e-10 8.0e-10 1.6e-09
4 Liver intron excision ratio chr1:254535612:254536577 0.03 0.02 4.5e-03 0.01 -0 0 -0 2.9e-02 3.9e-01 7.4e-02 4.9e-01
5 OFC mRNA stability ENSRNOG00000042786 0.19 0.13 4.2e-03 0.1 0.05 0.05 0.08 2.5e-03 2.2e-02 2.6e-02 6.6e-03
6 PL gene expression ENSRNOG00000042786 0.1 0.07 2.5e-06 0.07 0.08 0.08 0.07 6.2e-06 1.5e-06 1.4e-06 2.5e-06
7 PL mRNA stability ENSRNOG00000042786 0.11 0.07 2.5e-06 0.02 0.06 0.04 0.04 1.3e-02 4.2e-05 3.2e-04 5.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail3.09.619.64.41.41.44.34.22.41.2
BMI without tail0.71.53.51.90.10.11.81.80.3-0.1
Body weight3.816.331.85.62.02.05.65.33.41.7
Epididymis fat weight2.76.415.13.90.20.23.83.41.7-0.1
Glucose2.74.26.22.41.61.52.52.42.21.5
Heart weight0.81.12.71.60.60.61.41.50.30.5
Left kidney weight5.616.119.54.43.63.64.44.44.03.5
Right kidney weight4.512.818.34.33.03.04.24.13.32.8
Tail length0.10.30.60.1-0.7-0.70.10.0-0.7-0.8
Length with tail0.93.26.22.50.90.92.52.31.60.8
Length without tail3.37.311.83.41.81.83.43.22.81.7
Liver weight, left0.40.71.30.7-1.1-1.10.80.40.1-1.1
Liver weight, right2.43.97.82.60.70.72.82.72.00.6
Parametrial fat weight0.81.62.61.6-1.0-1.01.61.60.4-1.2
Retroperitoneal fat weight3.511.724.04.91.21.24.94.72.81.0
Intraocular pressure0.60.91.50.8-1.1-1.10.60.7-0.8-1.2
Extensor digitorum longus weight0.10.40.90.9-0.2-0.20.90.70.4-0.3
Soleus weight3.610.616.13.62.62.54.03.83.52.5
Tibialis anterior weight0.20.81.1-0.5-1.0-1.0-0.6-0.9-0.9-1.1
Tibia length1.64.46.02.41.81.82.42.32.21.7
Number of licking bursts0.70.81.5-0.6-1.2-1.2-0.5-0.3-0.9-1.2
Food consumed during 24 hour testing period0.20.20.40.30.50.60.40.70.10.5
Times rat made contact with spout0.60.61.31.00.50.41.11.00.80.4
Mean time between licks in bursts0.71.01.7-0.5-1.1-1.1-0.8-0.7-1.3-1.2
Mean num. licks in bursts2.53.03.41.71.81.81.71.41.71.8
Std. dev. time between licks in bursts2.53.03.9-1.5-1.9-1.9-1.6-1.3-1.9-2.0
Water consumed over 24 hours1.61.82.11.21.41.41.41.41.31.3
Indifference point 0 sec0.61.02.61.60.10.11.51.30.6-0.0
Indifference point AUC1.61.93.3-1.0-1.7-1.8-0.7-1.0-1.0-1.8
Indifference point function ln k0.50.71.30.31.11.10.40.70.61.1
Indifference point function log k0.50.71.30.31.11.10.40.70.61.1
Delay discounting total patch changes 0 sec0.40.71.81.3-0.2-0.21.31.00.4-0.3
Delay discounting total patch changes 12 sec0.60.81.7-0.1-1.2-1.2-0.0-0.4-0.7-1.3
Delay discounting total patch changes 18 sec1.21.63.6-0.1-1.8-1.80.0-0.4-0.9-1.9
Delay discounting total patch changes 24 sec2.83.56.5-0.7-2.4-2.5-0.8-1.4-1.8-2.5
Delay discounting total patch changes 6 sec0.50.71.21.1-0.7-0.71.10.90.0-0.9
Delay discounting time to switch 0 sec0.10.10.2-0.10.40.4-0.3-0.4-0.30.3
Delay discounting water rate 0 sec0.10.20.50.60.10.10.70.60.60.1
Delay discounting water rate 12 sec0.10.20.50.3-0.4-0.40.50.70.0-0.4
Delay discounting water rate 18 sec0.60.81.51.00.70.71.01.20.90.7
Delay discounting water rate 24 sec0.50.71.91.10.30.31.21.40.70.2
Delay discounting water rate 6 sec1.01.42.10.91.11.21.01.41.51.1
Locomotor activity1.52.43.01.71.41.51.61.71.51.4
Locomotor testing distance3.35.46.12.32.32.42.42.52.32.3
Locomotor testing rearing1.11.82.61.41.21.31.51.61.31.2
Light reinforcement 10.50.91.6-1.1-0.6-0.6-1.2-1.3-0.9-0.5
Light reinforcement 20.30.51.2-1.0-0.2-0.1-1.1-0.9-0.4-0.1
Reaction time number correct0.10.20.30.3-0.5-0.50.50.40.0-0.6
Reaction time mean minus median0.00.00.0-0.0-0.2-0.10.10.20.2-0.1
Reaction time mean minus median AUC0.50.61.00.70.70.70.80.81.00.7
Reaction time num false alarms0.10.20.3-0.1-0.5-0.5-0.2-0.5-0.5-0.5
Reaction time num false alarms AUC0.00.00.10.1-0.1-0.10.1-0.2-0.1-0.1
Reaction time trials correct on left0.10.20.30.3-0.5-0.50.50.40.0-0.6
Reaction time trials on left0.10.20.30.3-0.5-0.50.50.40.0-0.5
Reaction time mean0.40.50.90.40.90.90.50.50.90.9
Reaction time mean AUC0.20.20.40.10.60.60.10.10.60.7
Median of all reaction times0.81.11.70.61.31.20.70.61.21.3
Reaction time omissions0.00.00.10.3-0.1-0.00.10.3-0.1-0.1
Reaction time false alarm rate0.10.10.4-0.3-0.2-0.2-0.5-0.6-0.5-0.1
Reaction time premature initiation rate2.23.04.51.71.81.71.71.42.11.7
Reaction time premature initiations2.43.55.21.91.61.52.21.82.31.6
Std. dev. reaction times0.30.30.70.70.30.30.70.80.70.3
Reaction time trials completed0.10.20.30.3-0.5-0.50.50.40.0-0.5
Reaction time trials AUC0.10.20.30.4-0.5-0.50.50.40.0-0.6
Social response proportion4.24.65.62.21.91.92.32.42.21.9
Social responses0.50.61.11.0-0.5-0.51.01.10.3-0.6
Social time1.21.62.51.21.01.01.51.61.51.0
Conditioned locomotion0.10.10.20.10.40.30.10.00.40.4
Cocaine response after cond. corrected0.20.20.4-0.20.60.7-0.2-0.1-0.00.6
Cocaine response after cond. not corrected0.30.30.6-0.70.30.3-0.7-0.8-0.30.3
Cocaine response before conditioning1.01.22.0-1.2-1.0-1.0-1.2-1.4-0.8-1.0
Saline control response0.10.10.2-0.10.50.4-0.1-0.10.20.5
Condit. Reinf. active minus inactive responses5.77.110.9-2.2-2.9-2.8-2.4-1.8-3.3-3.0
Condit. Reinf. active-inactive response ratio4.54.77.8-1.9-2.2-2.1-2.1-1.6-2.8-2.3
Condit. Reinf. active responses4.35.98.7-1.7-2.9-2.8-1.9-1.4-2.9-2.9
Condit. Reinf. inactive responses0.50.71.3-0.3-1.1-1.1-0.3-0.3-0.8-1.1
Condit. Reinf. lever presses2.63.65.2-1.3-2.2-2.1-1.6-1.4-2.2-2.3
Condit. Reinf. lever reinforcers received4.36.08.8-1.7-2.8-2.8-1.9-1.5-3.0-2.9
Pavlov. Cond. lever latency4.35.88.21.62.82.82.02.02.62.9
Pavlov. Cond. magazine entry latency0.30.40.80.5-0.8-0.90.3-0.2-0.4-0.9
Pavlov. Cond. change in total contacts2.63.65.9-1.0-2.3-2.3-1.2-1.2-2.1-2.4
Pavlov. Cond. index score1.72.34.1-0.5-1.9-1.9-0.8-1.0-1.6-2.0
Pavlov. Cond. latency score1.72.13.9-0.5-1.9-1.9-0.7-1.0-1.5-2.0
Pavlov. Cond. lever contacts1.72.43.8-0.8-1.9-1.8-1.1-1.2-1.7-1.9
Pavlov. Cond. magazine entry number0.40.51.0-0.30.91.0-0.20.20.61.0
Pavlov. Cond. intertrial magazine entries0.00.10.2-0.4-0.00.1-0.10.40.10.0
Pavlov. Cond. lever-magazine prob. diff.1.41.83.3-0.4-1.7-1.7-0.7-0.8-1.4-1.8
Pavlov. Cond. response bias1.62.23.8-0.6-1.9-1.9-0.8-1.0-1.7-2.0
Conditioned reinforcement - actives0.10.10.2-0.2-0.2-0.2-0.4-0.4-0.4-0.2
Conditioned reinforcement - inactives0.20.30.5-0.1-0.7-0.7-0.1-0.2-0.5-0.7
Conditioned locomotion0.10.10.3-0.6-0.1-0.1-0.4-0.50.3-0.0
Intermittent access intake day 1-15 change0.20.20.30.3-0.5-0.60.40.5-0.3-0.6
Intermittent access intake escalation0.60.61.41.10.20.21.11.20.50.1
Intermittent access intake escalation 20.40.40.90.80.20.20.90.90.50.2
Intermitt. access day 1 inactive lever presses0.40.51.1-0.1-1.0-1.0-0.1-0.0-0.6-1.0
Intermitt. access day 15 inactive lever presses0.30.40.7-0.3-0.7-0.7-0.4-0.4-0.8-0.7
Intermitt. access escalation Index0.40.40.60.50.60.60.60.60.80.6
Intermittent access day 1 total infusions1.31.52.1-1.0-1.4-1.4-0.9-1.0-1.2-1.5
Intermittent access day 15 total infusions0.60.61.3-0.2-1.1-1.1-0.1-0.0-0.8-1.1
Intermittent access terminal intake (last 3 days)0.60.61.2-0.5-1.0-1.1-0.4-0.3-0.8-1.1
Intermittent access total infusions0.90.91.7-0.7-1.3-1.3-0.5-0.5-0.9-1.3
Intermittent access day 1 locomotion0.10.10.10.20.40.40.20.20.40.3
Intermittent access day 15 total locomotion0.10.10.20.4-0.4-0.40.40.40.1-0.4
Intermittent access total locomotion0.20.30.60.30.50.50.50.50.80.5
Intermittent access standard deviation1.81.93.5-0.9-1.8-1.8-0.8-0.7-1.1-1.9
Cocaine induced anxiety1.21.43.0-0.11.61.70.10.11.21.7
Post-drug Anxiety0.50.50.90.30.90.90.40.40.80.9
Baseline Anxiety0.90.92.00.4-1.3-1.30.50.5-0.5-1.4
Lifetime Intake1.11.22.2-0.7-1.4-1.4-0.6-0.5-1.0-1.5
Incentive Sensitization - Responses0.40.40.8-0.2-0.8-0.9-0.1-0.2-0.6-0.8
Incentive Sensitization - Breakpoint0.40.40.8-0.3-0.9-0.9-0.1-0.2-0.6-0.9
Progressive ratio test 1 active lever presses0.30.30.50.0-0.7-0.6-0.1-0.0-0.6-0.7
Progressive ratio test 1 breakpoint0.70.71.1-0.5-1.0-1.0-0.6-0.5-1.0-1.1
Progressive ratio test 1 inactive lever presses0.80.91.3-0.7-1.1-1.1-0.7-0.7-1.0-1.1
Progressive ratio test 2 active lever presses0.30.30.60.1-0.7-0.80.20.2-0.5-0.8
Progressive ratio test 2 breakpoint0.40.50.9-0.1-0.9-0.9-0.00.0-0.7-1.0
Progressive ratio test 2 inactive lever presses0.91.01.8-0.6-1.3-1.3-0.6-0.5-1.0-1.4
Total sessions with >9 infusions1.31.42.71.50.70.71.61.61.20.6
Short access day 1 total inactive lever presses0.10.10.20.3-0.4-0.40.30.40.1-0.4
Short access day 10 total inactive lever presses0.00.00.10.1-0.3-0.30.10.2-0.1-0.3
Short access day 1 total infusions0.10.10.10.2-0.2-0.10.40.30.2-0.2
Short access day 10 total infusions0.91.01.4-0.8-1.1-1.1-0.8-0.8-1.0-1.2
Short access total infusions0.70.81.5-0.6-1.2-1.2-0.5-0.5-0.8-1.2
Short access day 1 locomotion0.20.20.5-0.3-0.7-0.6-0.3-0.3-0.4-0.7
Short access day 10 total locomotion2.42.63.81.51.61.71.51.51.91.6
Short access total locomotion1.21.31.61.11.11.11.11.11.31.1
Compulsive drug intake1.21.21.5-1.1-1.2-1.2-1.0-1.1-1.0-1.2
One hour access (0.3 mA shock)2.73.15.5-1.2-2.3-2.3-1.0-1.0-1.4-2.4
One hour access (shock baseline)0.10.10.20.3-0.4-0.40.30.30.1-0.4
Number of responses in last shaping day0.20.20.40.70.30.40.60.50.30.3
Context. condit. distance diff. score0.50.61.20.51.11.10.40.40.51.1
Locomotion velocity, session 12.42.64.2-1.7-1.3-1.3-1.9-2.0-1.4-1.3
Locomotion distance, session 10.10.20.3-0.00.60.5-0.1-0.20.30.6
Locomotion velocity, session 21.11.32.40.61.51.50.50.31.11.5
Locomotion distance, session 20.60.91.51.20.50.51.21.20.90.5
Locomotion velocity, session 30.30.40.60.60.80.70.50.30.40.7
Locomotion distance, session 31.92.12.81.41.71.61.41.21.11.6
Stereotopy head waving bouts, day 30.00.00.00.1-0.2-0.20.10.1-0.0-0.1
Stereotopy head waving duration, day 31.11.42.0-1.4-1.1-1.0-1.4-1.1-1.2-1.0
Locomotion velocity, session 70.00.00.0-0.0-0.1-0.10.1-0.1-0.1-0.1
Locomotion distance, session 70.20.30.40.30.70.60.40.20.50.7
Stereotopy head waving bouts, day 70.10.10.2-0.2-0.4-0.3-0.3-0.1-0.4-0.4
Stereotopy head waving duration, day 70.10.20.3-0.2-0.6-0.5-0.20.3-0.4-0.6
Locomotion velocity, session 80.20.30.5-0.70.30.3-0.7-0.70.00.4
Locomotion distance, session 80.50.81.30.61.21.10.60.50.71.2
Degree of sensitization distance2.12.22.5-1.6-1.5-1.4-1.5-1.5-1.2-1.5
Degree of sensitization stereotypy0.20.20.4-0.2-0.6-0.5-0.3-0.2-0.5-0.6
Condit. Reinf. active minus inactive responses0.50.51.3-0.3-0.6-0.6-0.7-0.8-1.1-0.7
Condit. Reinf. active-inactive response ratio0.60.61.3-0.6-0.6-0.6-0.9-0.9-1.1-0.6
Condit. Reinf. active responses0.50.61.30.1-0.8-0.9-0.3-0.6-1.1-0.9
Condit. Reinf. inactive responses0.40.51.00.1-0.9-1.0-0.1-0.3-0.8-1.0
Incentive salience index mean0.81.02.0-0.6-0.8-0.8-1.1-1.3-1.4-0.8
Condit. Reinf. lever presses0.91.22.3-0.8-0.9-0.9-1.2-1.5-1.2-0.9
Time in familiar zone, hab. session 10.80.71.40.41.21.20.40.50.71.2
Time in novel zone, hab. session 11.11.02.0-0.6-1.4-1.4-0.5-0.3-0.9-1.4
Total zone transitions, hab. session 10.91.32.11.40.80.81.41.31.10.7
Total locomotion distance, hab. session 10.10.10.2-0.0-0.4-0.4-0.1-0.2-0.2-0.4
Locomotion velocity, hab. session 10.00.10.10.0-0.3-0.3-0.1-0.2-0.3-0.4
Time in familiar zone, hab. session 21.01.02.20.1-1.4-1.40.10.2-0.8-1.5
Time in novel zone, hab. session 21.01.12.10.51.41.40.40.30.91.5
Total zone transitions, hab. session 21.11.43.21.80.70.71.61.40.80.6
Total locomotion distance, hab. session 20.50.71.81.30.40.41.20.90.60.3
Locomotion velocity, hab. session 20.40.51.21.10.40.41.00.70.50.3
Novel to familiar place preference ratio0.30.40.5-0.6-0.7-0.7-0.5-0.4-0.5-0.7
Novelty place preference0.30.30.5-0.6-0.7-0.7-0.5-0.3-0.5-0.7
Time in novel zone, NPP test0.60.61.1-0.6-1.0-1.0-0.4-0.2-0.7-1.0
Total zone transitions, NPP test0.40.61.71.30.10.01.20.90.60.0
Total locomotion distance, NPP test0.20.31.11.0-0.2-0.20.80.60.1-0.3
Locomotion velocity, NPP test0.20.31.11.00.30.20.80.60.40.2
Pavlov. Cond. lever latency0.10.10.20.1-0.4-0.40.40.3-0.1-0.4
Pavlov. Cond. magazine entry latency0.10.20.60.80.10.00.60.30.40.1
Pavlov. Cond. change in total contacts0.30.40.50.60.70.60.50.20.70.7
Pavlov. Cond. index score0.30.40.70.80.60.50.70.40.70.5
Pavlov. Cond. latency score0.20.30.50.70.60.50.60.30.70.5
Pavlov. Cond. lever contacts0.10.10.3-0.4-0.1-0.1-0.5-0.5-0.2-0.1
Pavlov. Cond. magazine entry number0.91.12.3-1.5-0.8-0.7-1.4-1.0-1.1-0.7
Pavlov. Cond. intertrial magazine entries0.00.00.10.30.00.00.30.2-0.2-0.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.30.60.30.30.50.20.50.3
Pavlov. Cond. response bias0.20.30.50.70.50.50.60.30.60.5
Bone: apparent density0.20.40.90.2-0.9-0.90.40.4-0.2-1.0
Bone surface0.10.10.40.5-0.1-0.10.50.60.2-0.2
Bone volume0.40.71.61.1-0.2-0.21.31.30.6-0.3
Bone: connectivity density0.10.10.1-0.4-0.3-0.3-0.3-0.3-0.4-0.3
Bone: cortical apparent density2.73.56.41.12.52.51.01.01.72.5
Bone: cortical area1.01.54.91.4-0.4-0.31.72.20.4-0.5
Bone: cortical porosity0.70.81.3-0.7-1.1-1.1-0.6-0.5-0.9-1.1
Bone: cortical porosity0.90.91.7-0.6-1.3-1.2-0.5-0.5-1.0-1.3
Bone: cortical thickness1.01.74.31.60.50.51.82.10.90.3
Bone: cortical thickness1.41.62.91.31.01.01.51.71.30.9
Bone: cortical tissue density2.63.46.31.02.52.40.90.81.72.5
Bone: elastic displacement0.10.20.3-0.2-0.5-0.5-0.2-0.3-0.5-0.5
Bone: elastic work1.52.02.71.61.21.21.71.61.31.2
Bone: endosteal estimation0.20.51.30.8-0.4-0.40.91.10.2-0.5
Bone: endosteal perimeter0.51.14.11.2-0.10.11.42.00.6-0.1
Bone: final force0.40.61.51.10.10.11.11.20.70.0
Bone: final moment0.50.82.01.30.10.11.31.40.70.0
Bone: marrow area0.20.51.40.8-0.4-0.41.01.20.2-0.5
Bone: maximum diameter0.71.33.71.1-0.8-0.71.41.90.3-0.9
Bone: maximum force0.30.61.71.00.20.31.01.30.60.1
Bone: maximum moment0.40.82.11.10.20.21.21.40.60.1
Bone: minimum diameter0.51.03.31.1-0.4-0.31.31.80.2-0.5
Bone: periosteal estimation0.91.85.41.6-0.3-0.21.92.30.7-0.4
Bone: periosteal perimeter1.32.27.71.6-0.10.02.02.81.0-0.3
Bone: post-yield work1.01.41.8-1.1-1.3-1.3-1.1-0.6-1.3-1.3
Bone: stiffness0.10.10.50.40.20.30.30.70.20.2
Bone: tissue strength0.40.40.7-0.5-0.6-0.6-0.6-0.7-0.8-0.6
Bone: trabecular number0.40.61.1-0.4-1.0-1.0-0.3-0.2-0.7-1.1
Bone: trabecular spacing0.20.20.4-0.4-0.4-0.4-0.5-0.6-0.4-0.4
Bone: trabecular thickness0.60.71.50.8-0.6-0.51.11.20.4-0.7
Bone: trabecular tissue density0.40.60.90.40.80.90.40.90.80.9
Breakpoint value in progressive ratio session1.41.62.6-0.8-1.6-1.5-0.9-0.8-1.3-1.6
Distance traveled before self-admin3.13.34.81.52.22.21.41.21.82.2
Distance traveled after self-admin4.65.16.42.12.42.42.11.92.52.4
Delta time in closed arm before/after self-admin0.90.91.20.81.11.00.80.81.01.1
Delta time in open arm before/after self-admin1.41.32.2-0.8-1.5-1.4-0.7-0.8-1.0-1.5
Diff in mean of infusions in LGA sessions1.31.52.4-1.4-0.9-0.8-1.6-1.3-1.6-0.8
Extinction: sum of active levers before priming1.61.62.0-1.3-1.4-1.4-1.1-1.1-1.0-1.4
Active lever presses in extinction session 60.10.10.2-0.2-0.5-0.50.0-0.00.0-0.4
Delta distance traveled before/after self-admin0.70.71.30.90.50.51.11.11.10.5
Delta ambulatory time before/after self-admin0.10.20.20.2-0.5-0.40.40.40.3-0.5
Time in closed arm before self-admin0.20.20.40.70.40.50.50.50.30.4
Time in closed arm after self-admin0.10.10.20.50.50.50.20.10.00.5
Time in open arm before self-admin0.40.41.1-1.1-0.2-0.3-0.9-0.9-0.3-0.1
Time in open arm after self-admin2.73.03.5-1.9-1.8-1.9-1.6-1.6-1.4-1.8
Sum of active levers in priming session hrs 5-60.80.82.1-1.4-0.5-0.5-1.1-1.0-0.5-0.5
Time to tail flick, vehicle, before self-admin0.10.10.30.4-0.1-0.10.50.60.4-0.1
Time to tail flick, vehicle, after self-admin0.70.71.30.41.00.90.70.61.21.0
Time to tail flick, test, before self-admin3.53.43.71.81.91.91.81.81.91.9
Time to tail flick, test, after self-admin0.20.20.60.8-0.0-0.00.70.60.3-0.1
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.10.30.3-0.0-0.00.10.3
Delta time to tail flick, test, before/after SA0.30.30.7-0.1-0.8-0.8-0.1-0.1-0.5-0.8
Ambulatory time before self-admin4.04.25.22.02.32.31.81.62.02.3
Ambulatory time after self-admin4.95.47.72.02.42.42.22.02.82.4
Total heroin consumption0.50.61.20.1-1.0-1.0-0.1-0.0-0.9-1.1
Area under the delay curve0.60.61.3-0.3-1.1-1.0-0.3-0.3-0.7-1.1
Delay disc. indifference point, 0s delay0.10.10.30.50.00.00.60.60.4-0.1
Delay disc. indifference point, 16s delay1.31.31.8-1.0-1.3-1.3-1.0-1.0-1.1-1.4
Delay disc. indifference point, 2s delay0.00.00.10.20.10.10.30.20.30.1
Delay disc. indifference point, 24s delay2.32.23.7-1.1-1.9-1.8-1.0-1.0-1.2-1.9
Delay disc. indifference point, 4s delay0.50.50.8-0.4-0.8-0.8-0.5-0.6-0.9-0.8
Delay disc. indifference point, 8s delay0.60.61.50.1-1.1-1.10.10.0-0.5-1.2
Delay discount exponential model param0.70.71.50.31.11.10.30.40.81.2
Delay discount hyperbolic model param0.40.40.80.20.90.80.20.20.60.9
Fecal boli incidents, locomotor time 10.20.30.3-0.5-0.6-0.6-0.4-0.5-0.4-0.6
Change in fecal boli incidents, locomotor task0.00.00.20.0-0.0-0.0-0.2-0.1-0.4-0.0
Time >=10cm from walls, locomotor time 10.10.10.5-0.70.0-0.0-0.4-0.6-0.10.1
Bouts of movement, locomotor time 11.31.52.9-0.5-1.7-1.7-0.5-0.6-1.0-1.7
Total resting periods, locomotor time 11.01.12.3-0.5-1.5-1.5-0.4-0.4-0.8-1.5
Rest time, locomotor task time 10.10.20.30.50.30.20.50.50.30.3
Distance moved, locomotor task time 10.10.10.20.20.20.20.10.10.40.2
Vertical activity count, locomotor time 11.11.22.20.91.41.50.50.60.71.4
Time >=10cm from walls, locomotor time 20.10.10.10.0-0.3-0.40.20.10.1-0.3
Bouts of movement, locomotor time 20.40.40.7-0.9-0.4-0.4-0.9-0.8-0.6-0.3
Total resting periods, locomotor time 20.30.30.5-0.7-0.4-0.4-0.7-0.6-0.5-0.4
Rest time, locomotor task time 20.40.40.70.60.80.80.40.50.80.7
Distance moved, locomotor task time 20.70.91.3-0.5-1.1-1.2-0.6-0.7-1.0-1.2
Vertical activity count, locomotor time 20.00.00.00.2-0.1-0.10.00.2-0.1-0.1
Weight adjusted by age3.33.76.62.61.41.42.42.31.71.3
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.3-0.0-0.0-0.1-0.10.10.0
Locomotion in novel chamber2.02.53.11.51.71.81.41.41.41.7
Locomotion in novel chamber post-restriction0.10.10.3-0.30.50.5-0.2-0.1-0.00.6
Progressive ratio1.11.31.8-1.1-1.0-1.0-1.3-1.2-1.4-1.0
Food seeking constrained by brief footshock2.53.13.7-1.6-1.8-1.9-1.6-1.6-1.9-1.9
Seeking ratio, punishment vs. effort0.00.00.10.2-0.0-0.10.30.20.1-0.0
Run reversals in cocaine runway, females1.71.72.51.21.21.21.21.31.61.2
Run reversals in cocaine runway, males1.21.21.9-1.2-0.9-0.8-1.3-1.4-1.0-0.8
Latency to leave start box in cocaine runway0.10.10.3-0.50.20.2-0.4-0.40.00.2
Latency to leave start box in cocaine runway, F0.40.40.90.00.90.90.10.10.60.9
Latency to leave start box in cocaine runway, M0.30.30.4-0.4-0.6-0.6-0.5-0.3-0.5-0.6
Cd content in liver1.71.93.0-1.6-1.1-1.0-1.7-1.5-1.6-1.0
Co content in liver0.80.91.50.61.21.10.70.51.11.2
Cu content in liver0.50.50.80.70.70.70.80.60.90.7
Fe content in liver0.00.00.10.2-0.0-0.10.30.20.0-0.1
K content in liver0.20.20.6-0.4-0.3-0.4-0.4-0.80.0-0.3
Mg content in liver0.90.91.4-0.8-1.2-1.2-0.7-0.9-0.7-1.1
Mn content in liver0.10.10.2-0.10.40.4-0.1-0.10.10.4
Na content in liver2.12.22.7-1.6-1.4-1.3-1.6-1.6-1.4-1.4
Rb content in liver2.22.83.4-1.5-1.6-1.7-1.6-1.9-1.7-1.6
Se content in liver0.60.81.4-1.1-0.6-0.6-1.2-1.2-0.7-0.6
Sr content in liver0.30.20.4-0.50.60.6-0.6-0.4-0.10.6
Zn content in liver0.40.40.9-0.20.90.9-0.3-0.40.31.0