Hub : Genes

Mfsd12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000039858 0.44 0.15 0.0e+00 0.43 0.42 0.42 0.42 1.8e-51 7.7e-50 7.4e-51 4.4e-51
2 BLA gene expression ENSRNOG00000039858 0.07 0.05 1.8e-04 0.08 0.07 0.08 0.07 3.7e-05 7.7e-05 4.7e-05 7.6e-05
3 BLA mRNA stability ENSRNOG00000039858 0.06 0.05 1.5e-03 0.03 0.04 0.04 0.04 1.1e-02 2.3e-03 5.1e-03 2.4e-03
4 Brain gene expression ENSRNOG00000039858 0.11 0.07 1.4e-08 0.08 0.08 0.08 0.08 1.5e-07 8.8e-08 1.3e-07 4.9e-08
5 Brain intron excision ratio chr7:8347925:8348496 0.05 0.04 1.5e-03 0.02 0.02 0.01 0.02 3.1e-03 2.7e-03 2.2e-02 3.5e-03
6 Brain intron excision ratio chr7:8348860:8349298 0.05 0.04 9.0e-04 0.02 0.02 0.02 0.02 2.8e-03 6.0e-03 3.3e-03 1.1e-02
7 Brain mRNA stability ENSRNOG00000039858 0.09 0.06 1.3e-06 0.06 0.06 0.04 0.05 3.6e-06 7.6e-06 5.6e-05 8.4e-06
8 LHb intron excision ratio chr7:8347708:8347795 0.14 0.1 1.6e-03 0.1 0.09 0.05 0.09 3.0e-03 4.0e-03 2.3e-02 4.6e-03
9 Liver gene expression ENSRNOG00000039858 0.07 0.05 1.4e-04 0.04 0.02 0.03 0.03 3.2e-05 8.7e-04 2.7e-04 1.9e-04
10 NAcc gene expression ENSRNOG00000039858 0.13 0.08 2.6e-08 0.09 0.09 0.09 0.09 2.5e-07 1.7e-07 2.3e-07 2.0e-07
11 NAcc intron excision ratio chr7:8347925:8348496 0.04 0.03 8.9e-04 0.02 0.02 0.02 0.02 1.4e-02 9.3e-03 6.1e-03 2.3e-02
12 OFC gene expression ENSRNOG00000039858 0.17 0.12 1.4e-03 0.14 0.11 0.1 0.12 4.2e-04 1.2e-03 2.7e-03 7.2e-04
13 PL gene expression ENSRNOG00000039858 0.12 0.08 1.8e-09 0.1 0.11 0.1 0.12 2.7e-08 5.3e-09 1.2e-07 2.0e-09
14 PL mRNA stability ENSRNOG00000039858 0.04 0.03 4.6e-03 0.03 0 0.01 0.01 3.8e-03 2.1e-01 3.9e-02 4.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail5.919.122.5-4.6-4.64.7-4.63.8-4.74.64.60.8-4.04.7-4.6-4.54.7
BMI without tail2.24.67.3-2.0-2.02.4-1.92.3-2.72.42.41.0-1.52.3-2.0-1.92.7
Body weight1.14.86.9-2.2-2.12.3-2.22.0-2.62.32.30.6-1.92.4-2.2-2.22.6
Epididymis fat weight0.20.40.80.80.8-0.40.80.10.2-0.3-0.30.80.9-0.60.80.7-0.2
Glucose1.11.62.1-1.3-1.31.4-1.31.2-1.41.41.40.4-1.11.3-1.2-1.21.4
Heart weight0.40.51.00.80.9-0.51.0-0.00.7-0.4-0.40.51.0-0.70.90.9-0.7
Left kidney weight0.20.41.90.00.1-0.6-0.1-1.00.8-0.8-0.9-1.4-0.3-0.40.0-0.0-0.8
Right kidney weight1.44.16.02.02.0-2.21.9-1.92.5-2.2-2.3-0.91.7-2.22.01.9-2.5
Tail length2.78.011.43.33.3-2.93.4-1.92.4-2.7-2.60.53.2-3.13.33.2-2.4
Length with tail1.66.07.32.62.7-2.72.6-2.22.5-2.6-2.6-0.52.3-2.72.62.5-2.5
Length without tail0.20.41.2-0.00.1-0.5-0.1-1.00.8-0.6-0.7-1.1-0.3-0.30.0-0.0-0.8
Liver weight, left2.33.64.7-1.9-1.82.2-1.92.0-2.02.22.10.9-1.62.1-1.9-1.92.0
Liver weight, right1.52.53.2-1.8-1.71.7-1.81.2-1.51.51.60.1-1.61.7-1.7-1.71.5
Parametrial fat weight0.40.71.11.01.1-0.91.1-0.40.7-0.7-0.60.41.1-0.91.01.0-0.7
Retroperitoneal fat weight0.61.93.2-1.0-1.11.4-1.11.5-1.81.61.71.0-0.71.5-1.2-1.21.8
Intraocular pressure0.30.42.30.40.50.20.70.9-0.40.40.41.50.9-0.10.50.60.4
Extensor digitorum longus weight4.216.821.8-3.9-3.94.6-3.94.4-4.64.74.62.1-3.14.4-4.0-3.94.6
Soleus weight8.123.728.5-5.2-5.15.2-5.34.1-5.04.94.90.8-4.75.3-5.2-5.35.0
Tibialis anterior weight0.82.93.6-1.9-1.81.8-1.81.4-1.81.71.60.2-1.71.8-1.8-1.81.8
Tibia length0.82.23.11.71.8-1.51.7-1.01.4-1.4-1.30.21.6-1.61.71.6-1.4
Number of licking bursts0.40.41.90.20.00.50.11.1-0.60.80.81.40.50.4-0.0-0.00.6
Food consumed during 24 hour testing period0.40.50.7-0.7-0.80.8-0.80.7-0.80.80.80.2-0.70.8-0.8-0.80.8
Times rat made contact with spout0.30.30.8-0.3-0.30.6-0.20.9-0.50.80.70.9-0.00.5-0.2-0.20.5
Mean time between licks in bursts3.44.86.82.62.5-2.22.6-1.42.0-2.1-2.00.52.5-2.32.52.5-2.0
Mean num. licks in bursts0.10.10.3-0.3-0.2-0.0-0.1-0.30.3-0.1-0.2-0.5-0.3-0.1-0.1-0.1-0.3
Std. dev. time between licks in bursts1.01.22.30.80.7-1.20.6-1.51.4-1.3-1.3-1.20.4-1.00.70.7-1.4
Water consumed over 24 hours0.50.61.5-1.0-1.00.5-1.1-0.2-0.30.30.3-1.1-1.20.7-1.0-1.00.3
Indifference point 0 sec0.20.20.4-0.5-0.60.5-0.60.2-0.50.50.5-0.1-0.60.5-0.5-0.60.5
Indifference point AUC1.01.11.51.21.2-1.11.2-0.71.1-1.1-1.1-0.01.1-1.11.11.2-1.1
Indifference point function ln k0.20.40.5-0.5-0.60.6-0.60.6-0.60.70.70.3-0.50.7-0.5-0.60.6
Indifference point function log k0.20.40.5-0.5-0.60.6-0.60.6-0.60.70.70.3-0.50.7-0.5-0.60.6
Delay discounting total patch changes 0 sec0.10.20.3-0.4-0.50.4-0.50.3-0.50.50.50.1-0.40.5-0.4-0.50.5
Delay discounting total patch changes 12 sec0.40.51.1-0.4-0.50.8-0.31.1-0.91.00.90.9-0.10.6-0.4-0.40.9
Delay discounting total patch changes 18 sec0.81.11.51.21.2-1.11.2-0.81.0-1.1-1.0-0.11.1-1.11.11.1-1.0
Delay discounting total patch changes 24 sec0.10.10.20.30.2-0.40.3-0.40.2-0.4-0.5-0.30.2-0.40.30.3-0.2
Delay discounting total patch changes 6 sec0.10.20.30.60.4-0.50.5-0.30.5-0.3-0.40.10.4-0.40.50.4-0.5
Delay discounting time to switch 0 sec1.42.14.0-1.9-1.91.3-1.90.4-1.11.11.0-1.0-2.01.5-1.8-1.71.1
Delay discounting water rate 0 sec0.30.42.10.70.50.10.60.9-0.30.50.51.40.9-0.00.50.50.3
Delay discounting water rate 12 sec1.21.84.0-0.7-0.81.5-0.72.0-1.61.71.81.6-0.31.3-0.9-0.91.6
Delay discounting water rate 18 sec1.01.36.41.00.80.31.11.6-0.80.80.82.51.5-0.10.90.80.8
Delay discounting water rate 24 sec1.62.39.70.20.11.20.32.5-1.71.91.93.10.90.80.10.11.7
Delay discounting water rate 6 sec0.71.03.21.11.1-0.31.40.70.00.10.01.81.5-0.71.11.2-0.0
Locomotor activity3.35.27.42.12.0-2.62.0-2.72.6-2.7-2.7-1.41.5-2.42.02.0-2.6
Locomotor testing distance1.83.04.41.71.6-2.01.6-2.01.8-2.1-2.0-0.91.3-1.81.61.6-1.8
Locomotor testing rearing0.00.00.10.30.3-0.10.20.1-0.1-0.10.10.30.3-0.10.30.20.1
Light reinforcement 15.19.311.33.13.1-3.33.3-2.73.3-3.1-3.2-0.52.8-3.43.23.2-3.3
Light reinforcement 21.51.92.41.51.5-1.61.5-1.31.4-1.5-1.4-0.21.3-1.51.51.4-1.4
Reaction time number correct0.71.12.4-0.5-0.61.1-0.51.6-1.31.41.31.4-0.10.9-0.5-0.61.3
Reaction time mean minus median0.70.91.51.11.0-1.10.9-1.00.8-1.2-1.1-0.50.9-1.01.00.8-0.8
Reaction time mean minus median AUC0.40.63.0-0.2-0.2-0.5-0.5-1.30.5-0.9-0.7-1.7-0.6-0.1-0.2-0.4-0.5
Reaction time num false alarms0.00.10.2-0.0-0.10.3-0.00.5-0.10.30.30.40.10.2-0.1-0.00.1
Reaction time num false alarms AUC0.20.20.7-0.1-0.10.5-0.00.8-0.50.60.60.80.20.4-0.1-0.10.5
Reaction time trials correct on left0.71.12.4-0.5-0.61.1-0.51.6-1.31.41.31.4-0.10.9-0.5-0.61.3
Reaction time trials on left0.71.02.2-0.5-0.61.1-0.51.5-1.21.31.31.3-0.20.9-0.6-0.61.2
Reaction time mean0.20.31.7-0.2-0.3-0.3-0.5-0.90.1-0.6-0.4-1.3-0.60.0-0.3-0.4-0.1
Reaction time mean AUC0.20.31.6-0.3-0.4-0.2-0.6-0.80.0-0.5-0.3-1.2-0.70.1-0.4-0.5-0.0
Median of all reaction times0.40.51.5-0.7-0.80.3-1.0-0.4-0.3-0.00.1-1.2-1.10.6-0.9-0.90.3
Reaction time omissions0.20.30.60.60.5-0.70.4-0.70.4-0.7-0.6-0.50.4-0.50.40.4-0.4
Reaction time false alarm rate0.00.00.0-0.1-0.10.0-0.1-0.10.1-0.1-0.1-0.2-0.10.0-0.1-0.1-0.1
Reaction time premature initiation rate0.91.22.21.41.3-0.91.4-0.10.8-0.5-0.61.01.5-1.11.31.3-0.8
Reaction time premature initiations0.71.03.31.31.1-0.31.30.70.10.10.11.81.5-0.61.11.1-0.1
Std. dev. reaction times0.30.41.00.50.4-0.80.2-1.00.6-1.0-0.8-1.00.2-0.50.40.2-0.6
Reaction time trials completed0.71.02.2-0.5-0.61.1-0.51.5-1.21.31.31.3-0.20.9-0.6-0.61.2
Reaction time trials AUC0.81.12.7-0.4-0.51.1-0.41.6-1.31.41.41.5-0.00.9-0.5-0.51.3
Social response proportion0.80.81.70.60.7-0.90.7-1.01.3-1.1-1.1-0.60.5-0.90.80.8-1.3
Social responses7.69.913.52.83.0-3.42.9-3.33.7-3.6-3.7-1.52.3-3.42.93.0-3.7
Social time0.70.91.3-0.9-0.91.1-0.91.0-1.11.11.10.5-0.71.1-0.9-0.91.1
Conditioned locomotion2.02.44.5-1.1-1.11.7-1.02.1-1.92.02.01.6-0.61.5-1.1-1.11.9
Cocaine response after cond. corrected5.15.78.7-2.0-2.12.7-2.02.9-2.72.92.91.8-1.52.6-2.1-2.12.7
Cocaine response after cond. not corrected5.66.29.4-2.1-2.22.8-2.03.1-2.83.13.11.9-1.52.6-2.1-2.12.8
Cocaine response before conditioning0.50.60.90.60.7-0.90.6-0.90.7-1.0-0.9-0.60.5-0.80.70.7-0.7
Saline control response0.10.10.3-0.2-0.20.3-0.10.5-0.60.50.40.5-0.00.3-0.1-0.10.6
Condit. Reinf. active minus inactive responses2.12.54.31.91.9-1.52.1-0.61.3-1.2-1.20.82.0-1.71.91.9-1.3
Condit. Reinf. active-inactive response ratio0.50.52.60.70.70.10.80.9-0.30.40.41.61.0-0.20.60.70.3
Condit. Reinf. active responses2.12.93.81.91.8-1.81.9-1.31.8-1.7-1.7-0.01.7-1.91.91.9-1.8
Condit. Reinf. inactive responses1.31.72.41.11.0-1.51.1-1.51.5-1.5-1.6-0.90.8-1.41.21.1-1.5
Condit. Reinf. lever presses2.02.84.52.02.0-1.72.1-0.91.2-1.4-1.40.62.0-1.82.02.0-1.2
Condit. Reinf. lever reinforcers received1.62.33.41.71.7-1.51.8-0.91.5-1.3-1.40.31.7-1.71.71.8-1.5
Pavlov. Cond. lever latency0.81.11.4-1.0-1.11.2-1.11.0-0.81.21.20.3-0.91.2-1.1-1.10.8
Pavlov. Cond. magazine entry latency0.50.61.10.70.8-0.90.6-0.90.7-1.0-0.9-0.60.5-0.80.70.6-0.7
Pavlov. Cond. change in total contacts0.81.21.61.11.2-1.11.2-0.81.0-1.1-1.10.01.1-1.21.31.2-1.0
Pavlov. Cond. index score0.91.11.51.11.2-1.21.1-1.00.8-1.2-1.1-0.21.0-1.21.21.1-0.8
Pavlov. Cond. latency score0.81.01.51.01.1-1.21.0-1.10.9-1.2-1.1-0.50.8-1.11.01.0-0.9
Pavlov. Cond. lever contacts0.71.01.41.11.2-1.01.2-0.70.7-1.0-1.00.11.1-1.11.21.2-0.7
Pavlov. Cond. magazine entry number0.81.01.7-1.0-1.01.2-0.91.2-0.91.31.20.6-0.71.1-1.0-0.90.9
Pavlov. Cond. intertrial magazine entries0.60.71.4-0.4-0.70.9-0.51.2-1.11.21.10.9-0.20.8-0.6-0.61.1
Pavlov. Cond. lever-magazine prob. diff.0.91.11.61.11.2-1.21.1-1.10.9-1.3-1.2-0.40.9-1.21.11.1-0.9
Pavlov. Cond. response bias1.72.33.21.71.8-1.61.8-1.11.2-1.5-1.50.11.7-1.71.81.7-1.2
Conditioned reinforcement - actives2.72.63.51.71.6-1.71.6-1.51.9-1.8-1.7-0.41.4-1.71.61.6-1.9
Conditioned reinforcement - inactives0.91.02.0-0.6-0.61.1-0.51.4-1.31.31.41.2-0.31.0-0.6-0.61.3
Conditioned locomotion7.59.010.83.23.2-3.23.3-2.43.2-3.0-3.0-0.23.0-3.33.23.2-3.2
Intermittent access intake day 1-15 change5.95.98.32.82.8-2.52.9-1.62.2-2.3-2.20.42.7-2.62.82.8-2.2
Intermittent access intake escalation5.65.59.42.92.9-2.23.1-0.91.6-1.8-1.71.43.1-2.42.92.9-1.6
Intermittent access intake escalation 26.96.811.23.23.2-2.53.4-1.22.0-2.1-2.11.13.3-2.83.23.2-2.0
Intermitt. access day 1 inactive lever presses0.50.51.10.90.9-0.51.00.10.4-0.2-0.30.81.1-0.70.90.9-0.4
Intermitt. access day 15 inactive lever presses0.40.40.80.80.7-0.50.8-0.00.6-0.3-0.20.60.9-0.50.70.7-0.6
Intermitt. access escalation Index0.50.52.1-0.7-0.80.1-0.9-0.70.1-0.3-0.2-1.4-1.00.3-0.8-0.8-0.1
Intermittent access day 1 total infusions0.10.10.2-0.3-0.40.3-0.40.1-0.40.10.3-0.1-0.30.4-0.4-0.40.4
Intermittent access day 15 total infusions1.41.62.81.71.5-1.21.6-0.50.8-1.1-0.90.81.7-1.31.51.5-0.8
Intermittent access terminal intake (last 3 days)0.91.01.51.21.0-1.11.1-0.80.9-1.2-1.0-0.01.1-1.11.01.0-0.9
Intermittent access total infusions0.10.10.30.60.4-0.30.5-0.00.1-0.3-0.10.40.6-0.30.40.4-0.1
Intermittent access day 1 locomotion0.20.20.40.60.5-0.40.6-0.10.2-0.4-0.20.40.6-0.40.50.5-0.2
Intermittent access day 15 total locomotion2.93.14.62.22.0-1.82.1-1.11.5-1.7-1.50.52.1-1.82.02.0-1.5
Intermittent access total locomotion0.80.91.41.21.0-1.01.1-0.70.8-1.1-0.90.11.1-1.01.01.0-0.8
Intermittent access standard deviation2.93.14.42.12.0-1.72.1-1.01.7-1.6-1.50.42.0-1.82.02.0-1.7
Cocaine induced anxiety1.11.32.70.60.7-1.20.6-1.61.4-1.4-1.5-1.60.3-1.10.70.7-1.4
Post-drug Anxiety1.11.24.50.30.4-1.10.2-1.71.2-1.4-1.5-2.1-0.2-0.90.40.4-1.2
Baseline Anxiety0.10.10.40.30.20.00.20.3-0.10.20.20.70.4-0.00.20.20.1
Lifetime Intake0.00.00.10.30.1-0.20.2-0.10.0-0.3-0.10.00.3-0.10.10.1-0.0
Incentive Sensitization - Responses0.40.40.70.80.7-0.50.8-0.10.6-0.5-0.40.60.8-0.60.70.7-0.6
Incentive Sensitization - Breakpoint0.50.50.60.80.8-0.60.8-0.30.7-0.6-0.60.40.8-0.70.80.8-0.7
Progressive ratio test 1 active lever presses0.20.20.6-0.2-0.30.5-0.30.7-0.70.50.70.5-0.10.5-0.3-0.30.7
Progressive ratio test 1 breakpoint0.30.30.6-0.3-0.50.6-0.40.6-0.80.50.70.3-0.30.6-0.5-0.50.8
Progressive ratio test 1 inactive lever presses0.00.00.00.10.0-0.10.0-0.00.0-0.1-0.0-0.00.0-0.00.00.0-0.0
Progressive ratio test 2 active lever presses0.20.20.50.70.6-0.40.60.00.3-0.3-0.20.50.7-0.40.60.6-0.3
Progressive ratio test 2 breakpoint0.30.30.50.70.6-0.60.6-0.40.7-0.7-0.6-0.00.6-0.60.60.6-0.7
Progressive ratio test 2 inactive lever presses0.10.10.10.20.1-0.30.2-0.30.4-0.4-0.2-0.20.2-0.20.10.1-0.4
Total sessions with >9 infusions0.20.21.3-0.1-0.2-0.3-0.3-0.70.4-0.6-0.5-1.1-0.4-0.1-0.2-0.2-0.4
Short access day 1 total inactive lever presses0.00.00.00.20.2-0.10.2-0.1-0.0-0.2-0.1-0.00.2-0.20.20.20.0
Short access day 10 total inactive lever presses0.10.10.40.40.4-0.10.50.4-0.10.20.20.60.6-0.10.40.40.1
Short access day 1 total infusions0.30.31.50.1-0.0-0.5-0.1-0.90.3-0.9-0.7-1.2-0.2-0.3-0.0-0.0-0.3
Short access day 10 total infusions0.00.00.10.2-0.1-0.0-0.00.0-0.1-0.20.00.00.10.0-0.1-0.10.1
Short access total infusions0.10.10.6-0.0-0.2-0.2-0.3-0.40.0-0.5-0.3-0.8-0.2-0.0-0.2-0.2-0.0
Short access day 1 locomotion0.70.71.30.90.7-1.00.7-1.10.9-1.1-0.9-0.70.6-0.80.70.7-0.9
Short access day 10 total locomotion3.74.05.82.42.3-2.02.4-1.21.8-1.8-1.70.62.3-2.12.32.3-1.8
Short access total locomotion0.80.81.41.00.8-1.00.9-0.90.8-1.2-1.0-0.40.8-0.90.80.8-0.8
Compulsive drug intake0.80.71.4-1.2-0.90.9-1.00.4-0.80.90.7-0.2-1.10.9-0.9-0.90.8
One hour access (0.3 mA shock)0.20.30.4-0.4-0.50.6-0.50.5-0.60.50.70.3-0.40.6-0.5-0.50.6
One hour access (shock baseline)0.10.10.60.40.20.00.30.4-0.10.10.30.80.50.00.20.20.1
Number of responses in last shaping day0.10.10.20.40.3-0.40.3-0.40.3-0.5-0.4-0.30.3-0.40.30.3-0.3
Context. condit. distance diff. score0.30.40.5-0.5-0.60.7-0.60.6-0.60.60.70.2-0.50.7-0.7-0.70.6
Locomotion velocity, session 11.01.12.30.50.6-1.10.5-1.51.4-1.3-1.3-1.40.1-1.00.60.6-1.4
Locomotion distance, session 10.60.83.4-0.1-0.1-0.7-0.2-1.41.0-0.9-1.0-1.8-0.6-0.5-0.0-0.0-1.0
Locomotion velocity, session 23.94.67.91.61.6-2.41.5-2.82.7-2.6-2.7-2.10.9-2.21.71.7-2.7
Locomotion distance, session 22.02.85.81.00.9-1.80.9-2.42.2-2.0-2.1-2.10.3-1.61.01.0-2.2
Locomotion velocity, session 35.66.47.92.72.8-2.72.8-2.02.6-2.6-2.5-0.22.5-2.82.82.8-2.6
Locomotion distance, session 30.00.00.10.10.2-0.00.20.10.1-0.0-0.00.20.2-0.10.20.2-0.1
Stereotopy head waving bouts, day 34.35.16.42.22.2-2.52.2-2.32.5-2.5-2.5-1.01.8-2.52.22.2-2.5
Stereotopy head waving duration, day 34.96.07.22.52.5-2.72.5-2.32.6-2.6-2.6-0.82.1-2.72.52.5-2.6
Locomotion velocity, session 70.80.91.40.80.8-1.00.8-1.11.2-1.0-1.1-0.60.6-1.00.90.9-1.2
Locomotion distance, session 70.10.20.8-0.1-0.00.40.10.7-0.40.50.50.90.20.2-0.0-0.00.4
Stereotopy head waving bouts, day 70.30.42.0-0.3-0.2-0.3-0.4-1.00.5-0.6-0.5-1.4-0.6-0.1-0.3-0.3-0.5
Stereotopy head waving duration, day 70.50.62.70.10.1-0.7-0.1-1.40.9-1.0-0.9-1.7-0.4-0.50.00.0-0.9
Locomotion velocity, session 81.01.24.10.30.3-1.10.1-1.81.4-1.4-1.4-2.0-0.3-0.80.20.2-1.4
Locomotion distance, session 80.10.20.50.20.1-0.50.1-0.70.7-0.5-0.6-0.7-0.0-0.40.20.2-0.7
Degree of sensitization distance0.40.40.5-0.6-0.70.6-0.70.5-0.70.60.60.0-0.60.7-0.7-0.70.7
Degree of sensitization stereotypy1.61.83.2-1.6-1.61.1-1.80.3-1.00.90.9-1.0-1.81.4-1.6-1.61.0
Condit. Reinf. active minus inactive responses3.94.35.32.22.1-2.22.2-1.82.3-2.1-2.2-0.41.9-2.22.22.2-2.3
Condit. Reinf. active-inactive response ratio1.92.03.11.71.7-1.41.8-0.81.3-1.2-1.20.41.7-1.51.71.7-1.3
Condit. Reinf. active responses3.64.46.51.91.9-2.31.9-2.32.5-2.4-2.4-1.21.5-2.21.91.9-2.5
Condit. Reinf. inactive responses1.11.32.80.70.6-1.20.5-1.71.5-1.4-1.5-1.40.2-1.10.70.7-1.5
Incentive salience index mean2.32.74.31.51.4-1.81.4-1.92.1-1.9-1.9-1.11.1-1.71.41.4-2.1
Condit. Reinf. lever presses0.60.84.0-0.2-0.3-0.6-0.4-1.51.0-0.9-0.9-2.0-0.8-0.3-0.3-0.3-1.0
Time in familiar zone, hab. session 11.91.82.61.51.5-1.31.6-0.81.2-1.2-1.20.31.5-1.51.61.6-1.2
Time in novel zone, hab. session 11.00.92.0-1.1-1.20.7-1.3-0.1-0.40.50.5-1.2-1.40.9-1.2-1.20.4
Total zone transitions, hab. session 11.21.73.40.80.7-1.40.7-1.81.7-1.6-1.6-1.60.3-1.20.80.8-1.7
Total locomotion distance, hab. session 11.92.76.40.60.6-1.70.5-2.52.2-2.0-2.1-2.5-0.1-1.40.80.8-2.2
Locomotion velocity, hab. session 12.02.85.71.01.0-1.80.9-2.42.2-2.1-2.1-2.10.4-1.61.11.1-2.2
Time in familiar zone, hab. session 25.55.78.82.72.8-2.33.0-1.32.1-2.1-2.10.82.8-2.62.82.8-2.1
Time in novel zone, hab. session 24.04.06.6-2.4-2.41.9-2.60.8-1.61.61.6-1.0-2.52.1-2.4-2.41.6
Total zone transitions, hab. session 20.50.73.3-0.8-0.90.0-0.9-0.90.4-0.2-0.4-1.8-1.20.2-0.7-0.7-0.4
Total locomotion distance, hab. session 21.11.52.90.70.7-1.30.7-1.71.6-1.4-1.6-1.40.3-1.20.90.9-1.6
Locomotion velocity, hab. session 21.21.73.60.60.6-1.30.6-1.91.7-1.5-1.7-1.80.1-1.20.70.7-1.7
Novel to familiar place preference ratio3.33.46.2-2.3-2.21.6-2.50.5-1.41.31.3-1.3-2.51.9-2.3-2.31.4
Novelty place preference2.02.04.0-1.8-1.71.2-1.90.2-0.90.90.9-1.3-2.01.4-1.8-1.80.9
Time in novel zone, NPP test2.22.34.3-1.9-1.81.3-2.00.4-1.11.01.0-1.2-2.11.6-1.9-1.91.1
Total zone transitions, NPP test0.10.20.9-0.3-0.4-0.1-0.3-0.60.4-0.2-0.3-0.9-0.5-0.0-0.2-0.2-0.4
Total locomotion distance, NPP test0.30.41.9-0.5-0.5-0.2-0.5-0.80.6-0.3-0.5-1.4-0.8-0.0-0.3-0.3-0.6
Locomotion velocity, NPP test0.30.41.8-0.2-0.2-0.4-0.2-1.00.8-0.6-0.7-1.3-0.5-0.3-0.0-0.0-0.8
Pavlov. Cond. lever latency0.30.31.80.40.30.20.40.9-0.50.50.51.40.70.00.30.30.5
Pavlov. Cond. magazine entry latency2.33.04.02.01.9-1.82.0-1.21.7-1.7-1.70.11.9-1.91.91.9-1.7
Pavlov. Cond. change in total contacts0.10.10.10.20.2-0.30.2-0.30.4-0.3-0.3-0.10.2-0.30.30.3-0.4
Pavlov. Cond. index score0.50.61.20.50.5-0.80.4-1.11.0-0.9-1.0-0.90.2-0.70.50.5-1.0
Pavlov. Cond. latency score0.60.71.70.40.4-0.90.3-1.31.1-1.1-1.1-1.30.0-0.70.40.4-1.1
Pavlov. Cond. lever contacts0.50.62.7-0.2-0.1-0.5-0.2-1.20.9-0.8-0.8-1.6-0.6-0.3-0.1-0.1-0.9
Pavlov. Cond. magazine entry number0.50.70.8-0.9-0.80.9-0.90.7-0.90.80.80.1-0.80.9-0.8-0.80.9
Pavlov. Cond. intertrial magazine entries0.20.21.00.60.4-0.10.60.5-0.20.20.11.00.7-0.20.50.50.2
Pavlov. Cond. lever-magazine prob. diff.0.81.01.60.80.8-1.10.7-1.21.3-1.2-1.2-0.90.5-1.00.80.8-1.3
Pavlov. Cond. response bias0.91.11.41.11.1-1.21.1-1.01.2-1.1-1.1-0.31.0-1.21.11.1-1.2
Bone: apparent density0.91.57.0-0.6-0.6-0.6-0.8-1.91.2-1.2-1.2-2.6-1.3-0.3-0.6-0.5-1.2
Bone surface2.03.515.1-0.3-0.3-1.4-0.6-3.12.2-2.2-2.2-3.9-1.3-0.9-0.3-0.3-2.2
Bone volume2.13.515.1-0.3-0.3-1.4-0.6-3.12.2-2.2-2.2-3.9-1.3-0.9-0.3-0.2-2.2
Bone: connectivity density0.60.93.9-1.0-0.9-0.0-1.0-1.10.6-0.5-0.6-2.0-1.40.2-0.8-0.8-0.6
Bone: cortical apparent density1.11.41.9-1.0-1.21.2-1.31.0-1.41.11.30.2-1.01.4-1.4-1.41.4
Bone: cortical area0.61.02.2-1.1-1.20.5-1.4-0.4-0.20.10.2-1.4-1.50.8-1.3-1.30.2
Bone: cortical porosity0.60.71.10.60.7-0.90.6-1.11.1-1.0-1.0-0.80.4-0.80.60.6-1.1
Bone: cortical porosity0.30.31.3-0.1-0.1-0.4-0.2-0.90.7-0.6-0.6-1.2-0.4-0.2-0.2-0.1-0.7
Bone: cortical thickness1.01.72.8-1.5-1.61.2-1.70.6-1.01.01.0-0.6-1.61.4-1.6-1.61.0
Bone: cortical thickness0.10.10.70.30.20.10.30.5-0.30.30.30.80.5-0.00.30.30.3
Bone: cortical tissue density0.81.11.5-0.8-1.01.0-1.10.9-1.20.91.10.2-0.81.2-1.2-1.21.2
Bone: elastic displacement0.30.30.40.50.6-0.60.5-0.60.6-0.6-0.6-0.20.4-0.60.60.5-0.6
Bone: elastic work0.20.20.5-0.6-0.60.3-0.7-0.1-0.20.10.2-0.6-0.70.4-0.6-0.60.2
Bone: endosteal estimation0.20.41.0-0.8-0.80.4-0.9-0.1-0.20.20.3-0.8-1.00.6-0.9-0.90.2
Bone: endosteal perimeter0.40.92.10.40.4-1.00.2-1.41.2-1.2-1.2-1.4-0.0-0.70.30.3-1.2
Bone: final force1.01.73.4-1.6-1.71.0-1.80.1-0.70.70.7-1.2-1.81.3-1.7-1.70.7
Bone: final moment0.81.42.8-1.4-1.50.9-1.60.0-0.60.60.6-1.1-1.71.1-1.6-1.50.6
Bone: marrow area0.20.51.0-0.8-0.80.5-1.0-0.1-0.30.20.3-0.7-1.00.7-0.9-0.90.3
Bone: maximum diameter0.91.63.70.80.7-1.40.5-1.91.6-1.7-1.6-1.80.2-1.10.60.6-1.6
Bone: maximum force1.11.93.4-1.6-1.71.2-1.90.4-0.90.90.9-0.9-1.81.5-1.8-1.80.9
Bone: maximum moment0.91.63.0-1.5-1.61.1-1.70.3-0.80.80.8-0.9-1.71.3-1.7-1.60.8
Bone: minimum diameter0.10.31.3-0.3-0.3-0.2-0.5-0.70.4-0.4-0.4-1.1-0.60.1-0.5-0.4-0.4
Bone: periosteal estimation0.51.02.5-1.1-1.20.4-1.4-0.5-0.10.00.1-1.6-1.50.8-1.3-1.30.1
Bone: periosteal perimeter0.40.62.9-0.0-0.1-0.6-0.3-1.30.9-1.0-0.9-1.7-0.5-0.3-0.2-0.2-0.9
Bone: post-yield work0.60.91.2-0.8-1.01.0-1.00.8-0.90.91.00.1-0.81.1-1.1-1.00.9
Bone: stiffness2.64.26.4-2.3-2.42.0-2.51.2-1.71.81.7-0.5-2.42.2-2.5-2.41.7
Bone: tissue strength1.71.72.5-1.4-1.51.3-1.60.8-1.21.11.2-0.2-1.41.5-1.6-1.61.2
Bone: trabecular number1.21.94.30.60.7-1.50.6-2.11.8-1.8-1.9-1.90.1-1.30.70.8-1.8
Bone: trabecular spacing1.51.96.8-0.1-0.11.20.12.3-1.71.71.72.60.60.9-0.1-0.11.7
Bone: trabecular thickness2.12.511.9-0.7-0.7-0.9-0.9-2.51.7-1.6-1.6-3.5-1.6-0.4-0.7-0.6-1.7
Bone: trabecular tissue density2.63.75.7-1.4-1.62.1-1.62.2-2.42.22.41.4-1.02.1-1.7-1.82.4
Breakpoint value in progressive ratio session4.34.86.92.62.6-2.32.6-1.41.8-2.1-2.00.42.6-2.42.52.5-1.8
Distance traveled before self-admin0.20.20.4-0.5-0.50.4-0.60.0-0.30.30.3-0.4-0.70.4-0.6-0.60.3
Distance traveled after self-admin0.91.01.31.01.0-1.11.0-1.01.1-1.1-1.2-0.40.8-1.11.01.0-1.1
Delta time in closed arm before/after self-admin1.51.44.9-0.3-0.21.2-0.12.0-1.51.51.42.20.30.8-0.2-0.21.5
Delta time in open arm before/after self-admin1.21.11.7-1.2-1.21.1-1.30.7-0.91.01.1-0.2-1.21.2-1.3-1.30.9
Diff in mean of infusions in LGA sessions1.41.51.91.41.4-1.31.3-0.91.2-1.2-1.2-0.01.3-1.31.31.3-1.2
Extinction: sum of active levers before priming1.21.22.61.41.4-0.81.40.00.7-0.6-0.51.11.6-1.01.31.3-0.7
Active lever presses in extinction session 63.13.03.91.81.7-1.81.8-1.52.0-1.9-1.8-0.51.6-1.81.71.7-2.0
Delta distance traveled before/after self-admin1.41.51.91.31.3-1.31.3-1.11.2-1.3-1.3-0.21.2-1.41.31.3-1.2
Delta ambulatory time before/after self-admin1.71.82.51.31.2-1.51.3-1.41.5-1.5-1.6-0.71.0-1.51.31.3-1.5
Time in closed arm before self-admin0.81.02.0-1.3-1.30.7-1.3-0.0-0.70.50.5-1.1-1.40.9-1.2-1.20.7
Time in closed arm after self-admin0.00.00.10.10.2-0.10.30.0-0.20.0-0.20.10.1-0.20.30.30.2
Time in open arm before self-admin1.21.21.71.21.2-1.11.3-0.61.2-0.9-1.00.31.2-1.21.31.3-1.2
Time in open arm after self-admin0.70.71.3-0.8-0.81.0-0.90.9-0.71.01.10.5-0.71.0-0.9-0.90.7
Sum of active levers in priming session hrs 5-60.00.00.10.10.00.1-0.00.2-0.30.10.20.20.10.1-0.0-0.00.3
Time to tail flick, vehicle, before self-admin1.01.02.70.40.5-1.10.5-1.60.9-1.4-1.4-1.70.1-1.00.50.5-0.9
Time to tail flick, vehicle, after self-admin0.20.20.90.40.5-0.00.70.50.20.10.10.90.7-0.30.60.6-0.2
Time to tail flick, test, before self-admin0.70.72.60.00.0-0.7-0.0-1.31.0-1.1-1.0-1.6-0.3-0.50.10.1-1.0
Time to tail flick, test, after self-admin0.30.41.10.30.2-0.60.2-0.90.6-0.9-0.8-1.10.0-0.50.20.2-0.6
Delta time to tail flick, vehicle, before/after SA1.00.93.1-0.4-0.31.1-0.31.7-0.91.31.31.80.10.8-0.3-0.30.9
Delta time to tail flick, test, before/after SA0.20.20.90.50.4-0.10.60.4-0.30.10.11.00.7-0.20.50.50.3
Ambulatory time before self-admin0.20.20.3-0.4-0.50.4-0.50.2-0.40.30.4-0.1-0.50.5-0.5-0.50.4
Ambulatory time after self-admin0.50.60.70.80.8-0.80.7-0.80.8-0.8-0.8-0.30.6-0.80.70.7-0.8
Total heroin consumption1.82.12.91.51.4-1.61.4-1.41.5-1.7-1.6-0.61.3-1.61.41.4-1.5
Area under the delay curve1.81.92.8-1.6-1.61.4-1.70.8-1.31.31.2-0.4-1.61.5-1.6-1.61.3
Delay disc. indifference point, 0s delay6.16.711.6-3.1-3.02.4-3.40.9-2.02.02.0-1.6-3.42.7-3.1-3.12.0
Delay disc. indifference point, 16s delay0.10.10.2-0.4-0.50.3-0.40.1-0.40.30.3-0.2-0.40.3-0.4-0.40.4
Delay disc. indifference point, 2s delay5.05.68.3-2.7-2.72.3-2.91.2-2.32.12.0-0.8-2.82.5-2.7-2.72.3
Delay disc. indifference point, 24s delay0.40.40.6-0.8-0.80.7-0.70.5-0.60.70.60.2-0.60.6-0.7-0.70.6
Delay disc. indifference point, 4s delay1.01.02.2-1.3-1.30.8-1.4-0.0-0.60.60.5-1.1-1.50.9-1.2-1.20.6
Delay disc. indifference point, 8s delay1.01.01.5-1.0-0.91.2-0.91.2-1.11.21.20.6-0.71.1-0.9-0.91.1
Delay discount exponential model param1.61.72.41.51.5-1.31.6-0.81.3-1.2-1.20.31.5-1.41.51.5-1.3
Delay discount hyperbolic model param2.42.53.61.91.8-1.61.9-0.91.6-1.5-1.40.41.8-1.71.81.8-1.6
Fecal boli incidents, locomotor time 12.02.23.6-1.2-1.21.7-1.21.8-1.81.71.91.1-0.81.6-1.3-1.21.8
Change in fecal boli incidents, locomotor task0.80.72.10.30.4-0.90.2-1.41.1-1.1-1.1-1.4-0.1-0.70.30.3-1.1
Time >=10cm from walls, locomotor time 10.40.40.9-0.6-0.80.3-0.9-0.3-0.10.20.1-1.0-0.90.5-0.7-0.80.1
Bouts of movement, locomotor time 10.10.10.30.50.4-0.30.4-0.20.4-0.4-0.30.20.5-0.30.40.4-0.4
Total resting periods, locomotor time 10.20.20.30.60.4-0.50.4-0.40.5-0.6-0.4-0.10.4-0.40.40.4-0.5
Rest time, locomotor task time 10.20.20.30.50.4-0.50.2-0.60.5-0.6-0.5-0.30.2-0.40.30.2-0.5
Distance moved, locomotor task time 10.40.51.2-0.9-0.80.3-0.9-0.3-0.20.20.1-1.0-1.10.5-0.8-0.80.2
Vertical activity count, locomotor time 10.10.10.2-0.2-0.10.3-0.10.4-0.30.40.30.4-0.10.2-0.1-0.10.3
Time >=10cm from walls, locomotor time 21.11.11.7-0.8-1.01.2-0.91.2-1.31.31.30.8-0.71.1-1.0-0.91.3
Bouts of movement, locomotor time 20.70.71.60.40.4-0.90.3-1.21.3-1.0-1.0-1.20.1-0.70.40.4-1.3
Total resting periods, locomotor time 20.70.81.80.40.3-0.90.2-1.31.3-1.0-1.1-1.3-0.0-0.70.40.3-1.3
Rest time, locomotor task time 20.60.71.30.70.4-0.90.5-1.11.0-1.1-1.0-0.90.3-0.80.50.6-1.0
Distance moved, locomotor task time 20.91.01.7-0.8-0.81.1-0.81.3-1.11.31.21.0-0.51.0-0.8-0.81.1
Vertical activity count, locomotor time 21.11.22.6-0.5-0.51.2-0.61.6-1.31.41.41.6-0.21.0-0.7-0.71.3
Weight adjusted by age0.30.41.0-0.4-0.30.7-0.41.0-0.50.70.90.8-0.10.6-0.4-0.40.5
Seeking ratio, delayed vs. immediate footshock4.75.47.22.22.3-2.62.3-2.42.3-2.6-2.7-0.91.9-2.62.42.3-2.3
Locomotion in novel chamber0.50.60.90.80.8-0.70.9-0.30.7-0.5-0.70.40.9-0.90.90.9-0.7
Locomotion in novel chamber post-restriction0.60.70.91.00.9-1.00.9-0.80.7-1.0-1.0-0.10.8-0.90.91.0-0.7
Progressive ratio0.10.20.5-0.4-0.20.6-0.20.7-0.10.50.50.6-0.10.4-0.3-0.20.1
Food seeking constrained by brief footshock0.10.10.30.30.2-0.30.5-0.30.5-0.3-0.5-0.10.3-0.40.40.5-0.5
Seeking ratio, punishment vs. effort0.10.10.20.30.1-0.40.2-0.50.0-0.3-0.4-0.30.2-0.30.20.3-0.0
Run reversals in cocaine runway, females1.01.02.20.50.6-1.00.7-1.21.5-1.0-1.4-1.00.3-1.10.80.8-1.5
Run reversals in cocaine runway, males1.31.32.41.00.9-1.31.0-1.41.1-1.4-1.6-0.90.7-1.21.01.1-1.1
Latency to leave start box in cocaine runway1.21.33.10.90.6-1.30.5-1.81.3-1.6-1.4-1.50.3-1.10.70.5-1.3
Latency to leave start box in cocaine runway, F0.70.84.7-0.2-0.5-0.5-0.7-1.50.6-0.9-0.8-2.2-0.9-0.1-0.5-0.5-0.6
Latency to leave start box in cocaine runway, M2.62.54.31.92.0-1.42.0-0.51.4-1.2-1.01.02.1-1.61.91.8-1.4
Cd content in liver0.20.20.3-0.5-0.50.4-0.50.2-0.60.30.3-0.1-0.50.4-0.5-0.40.6
Co content in liver0.50.61.20.90.9-0.71.1-0.30.6-0.5-0.60.51.0-0.80.91.0-0.6
Cu content in liver0.20.31.4-0.5-0.5-0.0-0.6-0.60.3-0.2-0.2-1.2-0.80.2-0.5-0.5-0.3
Fe content in liver0.10.10.50.20.20.10.30.4-0.00.20.20.70.4-0.00.20.20.0
K content in liver0.30.31.3-0.2-0.2-0.3-0.3-0.90.7-0.5-0.7-1.1-0.5-0.2-0.2-0.2-0.7
Mg content in liver0.40.42.0-0.2-0.2-0.4-0.4-1.10.8-0.6-0.8-1.4-0.6-0.2-0.2-0.2-0.8
Mn content in liver2.22.56.80.50.5-1.60.3-2.52.2-2.0-2.0-2.6-0.2-1.20.50.5-2.2
Na content in liver0.90.91.7-1.2-1.20.8-1.30.2-0.60.70.6-0.6-1.31.0-1.2-1.20.6
Rb content in liver0.50.62.0-0.9-0.90.3-1.1-0.6-0.2-0.0-0.1-1.4-1.20.5-0.9-1.00.2
Se content in liver0.20.30.60.40.4-0.50.5-0.50.8-0.5-0.6-0.30.3-0.50.40.6-0.8
Sr content in liver0.30.31.80.30.30.30.50.8-0.40.50.51.30.60.00.30.40.4
Zn content in liver2.12.34.91.91.9-1.12.10.10.9-0.6-0.81.72.2-1.41.92.0-0.9