Hub : Genes

G4

Models

#	tissue	modality	RNA phenotype	h²	h² se	h² P	eQTL R²	BLUP R²	ENET R²	LASSO R²	eQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000039658	0.0830	0.0460	7.3e-10	0.083	0.084	0.089	0.052	1.7e-09	1.5e-09	4.8e-10	1.8e-06
2	Adipose	isoform ratio	ENSRNOT00000060819	0.0460	0.0260	1.5e-06	0.049	0.050	0.053	0.049	3.4e-06	3.0e-06	1.6e-06	3.4e-06
3	Adipose	isoform ratio	ENSRNOT00000117404	0.0450	0.0260	1.6e-06	0.049	0.049	0.051	0.049	3.7e-06	3.3e-06	2.1e-06	3.9e-06
4	BLA	gene expression	ENSRNOG00000039658	0.2401	0.1370	9.8e-10	0.121	0.151	0.162	0.155	5.1e-07	1.8e-08	4.9e-09	1.2e-08
5	BLA	isoform ratio	ENSRNOT00000060819	0.0990	0.0590	1.5e-04	0.045	0.061	0.021	0.070	2.0e-03	3.4e-04	2.5e-02	1.3e-04
6	BLA	isoform ratio	ENSRNOT00000117404	0.0990	0.0590	1.5e-04	0.044	0.060	0.021	0.067	2.1e-03	3.9e-04	2.6e-02	1.8e-04
7	Brain	gene expression	ENSRNOG00000039658	0.0860	0.0550	5.9e-06	0.042	0.042	0.035	0.041	7.8e-05	8.3e-05	3.0e-04	1.0e-04
8	Brain	isoform ratio	ENSRNOT00000060819	0.1271	0.0646	3.9e-12	0.135	0.121	0.115	0.122	1.7e-12	2.7e-11	8.2e-11	2.3e-11
9	Brain	isoform ratio	ENSRNOT00000117404	0.1277	0.0647	3.3e-12	0.136	0.122	0.116	0.122	1.4e-12	2.4e-11	7.6e-11	2.4e-11
10	LHb	isoform ratio	ENSRNOT00000060819	0.2348	0.1244	1.9e-03	0.112	0.157	0.023	0.123	1.3e-03	1.5e-04	9.1e-02	7.7e-04
11	LHb	isoform ratio	ENSRNOT00000117404	0.2336	0.1232	1.8e-03	0.115	0.157	0.036	0.124	1.2e-03	1.5e-04	4.8e-02	7.6e-04
12	Liver	gene expression	ENSRNOG00000039658	0.0630	0.0350	1.5e-04	0.019	0.024	0.026	0.027	3.2e-03	9.2e-04	5.6e-04	4.9e-04
13	Liver	isoform ratio	ENSRNOT00000060819	0.0778	0.0377	1.1e-11	0.107	0.064	0.081	0.077	6.3e-12	1.4e-07	2.9e-09	6.0e-09
14	Liver	isoform ratio	ENSRNOT00000117404	0.0757	0.0369	2.2e-11	0.104	0.061	0.079	0.079	1.2e-11	2.3e-07	4.0e-09	4.5e-09
15	NAcc	gene expression	ENSRNOG00000039658	0.0490	0.0310	1.1e-03	-0.003	0.028	0.005	0.003	7.2e-01	3.5e-03	1.3e-01	1.9e-01
16	NAcc	isoform ratio	ENSRNOT00000060819	0.1270	0.0681	1.1e-07	0.085	0.053	0.037	0.054	7.1e-07	8.0e-05	9.3e-04	7.1e-05
17	NAcc	isoform ratio	ENSRNOT00000117404	0.1280	0.0680	8.3e-08	0.085	0.053	0.036	0.054	6.9e-07	8.0e-05	9.9e-04	7.0e-05
18	OFC	gene expression	ENSRNOG00000039658	0.2571	0.1305	1.6e-04	0.032	0.115	0.115	0.081	6.1e-02	1.1e-03	1.1e-03	5.8e-03
19	PL	gene expression	ENSRNOG00000039658	0.1787	0.1149	1.3e-08	0.122	0.100	0.110	0.123	1.5e-09	4.9e-08	1.1e-08	1.4e-09
20	PL	isoform ratio	ENSRNOT00000060819	0.1500	0.0710	8.5e-12	0.140	0.156	0.172	0.153	9.3e-11	6.1e-12	4.5e-13	1.1e-11
21	PL	isoform ratio	ENSRNOT00000117404	0.1500	0.0710	5.9e-12	0.142	0.159	0.174	0.155	6.2e-11	4.0e-12	3.2e-13	7.5e-12

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method.

Trait associations

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21
Locomotion distance, session 7	7.3	9.3	12.2	-2.9	3.2	-3.2	-3.1	3.4	-3.4	-3.5	3.3	-3.3	2.5	-2.5	-0.4	3.4	-3.4	-2.9	3.2	-3.2	-3.0	-3.1	2.7	-2.7
Locomotion velocity, session 7	6.4	7.0	10.5	-2.3	2.8	-2.8	-2.7	2.9	-2.8	-3.2	2.8	-2.8	2.8	-2.8	0.2	3.0	-3.0	-2.2	2.5	-2.5	-2.6	-2.6	2.3	-2.4
Cocaine response before conditioning	5.3	6.4	14.6	2.6	-2.6	2.6	1.4	-2.0	1.9	2.7	-2.8	2.8	-3.8	3.8	0.1	-2.6	2.6	1.6	-2.7	2.7	3.1	2.3	-1.9	2.0
Weight adjusted by age	5.1	5.7	8.6	2.1	-2.5	2.4	1.7	-2.0	2.0	2.3	-2.7	2.7	-2.0	2.0	1.6	-2.9	2.9	2.4	-2.7	2.7	2.8	2.6	-2.3	2.3
Progressive ratio	4.7	5.5	11.3	2.0	-2.8	2.8	3.4	-3.2	3.2	3.0	-2.0	2.0	-0.6	0.7	-0.5	-2.3	2.3	2.6	-1.9	1.9	1.3	2.3	-2.8	2.8
Bone: marrow area	4.5	9.6	18.7	2.4	-2.9	2.8	2.1	-3.0	3.0	3.2	-3.4	3.4	-3.8	3.8	2.6	-3.2	3.2	2.3	-3.3	3.3	4.3	2.9	-2.6	2.6
Body weight	4.4	18.8	27.8	3.9	-5.2	5.2	4.8	-4.4	4.4	4.1	-4.5	4.5	-1.7	1.8	2.2	-4.5	4.5	4.9	-4.4	4.4	4.0	5.3	-4.9	4.9
Locomotion distance, session 8	4.3	6.4	9.2	-2.4	2.6	-2.7	-2.5	2.2	-2.2	-2.8	2.9	-2.9	2.3	-2.4	2.2	3.0	-3.0	-2.4	2.6	-2.6	-1.6	-2.4	2.5	-2.5
Bone: endosteal estimation	4.1	8.9	18.0	2.3	-2.8	2.7	2.0	-2.9	2.9	3.1	-3.2	3.2	-3.7	3.7	2.6	-3.0	3.0	2.1	-3.2	3.2	4.2	2.8	-2.4	2.5
Diff in mean of infusions in LGA sessions	4.0	4.5	7.0	-2.3	2.3	-2.3	-1.4	1.5	-1.5	-2.3	2.5	-2.5	2.2	-2.2	-0.0	2.3	-2.3	-1.9	2.6	-2.6	-2.0	-2.4	1.9	-1.9
Bone: trabecular spacing	3.9	5.0	8.0	1.6	-2.7	2.7	1.7	-1.7	1.7	1.9	-2.5	2.5	-2.5	2.6	1.5	-2.1	2.1	1.8	-2.5	2.5	2.8	2.5	-2.2	2.2
Context. condit. distance diff. score	3.4	4.1	6.6	-1.6	2.5	-2.6	-2.6	1.7	-1.7	-2.0	2.2	-2.2	1.0	-1.1	1.9	2.3	-2.3	-2.1	2.1	-2.1	-0.8	-2.3	2.2	-2.2
Bone: trabecular number	3.4	5.3	9.8	-1.5	2.5	-2.4	-1.5	1.6	-1.6	-2.0	2.5	-2.5	3.1	-3.1	-1.6	2.4	-2.4	-1.6	2.5	-2.5	-3.1	-2.3	2.3	-2.3
Cu content in liver	3.4	4.1	6.8	-1.4	1.9	-1.8	-1.8	2.3	-2.3	-2.2	2.0	-2.0	1.9	-1.9	-1.9	2.2	-2.2	-1.7	1.9	-1.9	-2.6	-2.1	2.1	-2.1
BMI without tail	3.2	6.6	8.9	2.0	-2.9	2.8	2.6	-2.3	2.3	3.0	-2.6	2.6	-2.9	3.0	-0.3	-2.8	2.8	2.2	-2.6	2.6	2.6	2.8	-2.6	2.6
Tail length	3.1	9.5	24.9	2.9	-3.4	3.3	2.0	-2.2	2.2	3.1	-2.8	2.8	-5.0	5.0	1.2	-3.5	3.5	1.6	-2.8	2.8	4.4	3.1	-2.1	2.1
Pavlov. Cond. lever latency	3.1	3.9	6.9	2.4	-2.0	2.0	2.4	-2.3	2.3	2.2	-2.1	2.1	0.3	-0.3	-1.1	-2.1	2.1	2.6	-2.1	2.1	0.4	1.9	-2.2	2.2
Condit. Reinf. lever presses	3.0	4.1	6.8	-2.6	2.3	-2.3	-2.1	1.7	-1.7	-2.3	2.2	-2.2	1.4	-1.4	1.5	2.3	-2.3	-2.0	2.1	-2.1	-1.1	-2.1	1.9	-1.9
Bone: periosteal estimation	3.0	6.2	10.3	1.4	-2.5	2.5	2.3	-2.7	2.7	2.7	-2.7	2.7	-2.6	2.6	1.8	-2.4	2.4	2.0	-2.6	2.6	3.2	2.6	-2.3	2.3
Time in novel zone, hab. session 1	2.9	2.8	5.4	2.1	-1.7	1.7	1.1	-1.7	1.7	1.9	-1.6	1.6	-1.6	1.6	1.8	-1.8	1.8	1.3	-1.6	1.6	2.3	1.5	-1.1	1.1
Time to tail flick, test, after self-admin	2.8	2.8	4.1	-1.0	1.8	-1.8	-1.6	1.7	-1.7	-1.8	1.8	-1.8	0.9	-0.9	-1.3	1.9	-1.9	-1.8	1.8	-1.8	-1.7	-1.8	2.0	-2.0
Tibia length	2.7	7.7	13.7	2.0	-2.8	2.8	2.4	-3.0	3.0	3.0	-3.0	3.0	-2.5	2.5	2.8	-2.4	2.4	2.4	-3.0	3.0	3.7	3.2	-2.4	2.5
Saline control response	2.7	3.6	6.3	1.9	-1.5	1.6	2.2	-2.1	2.1	2.2	-2.0	2.0	-0.7	0.7	-1.7	-2.5	2.5	2.2	-1.9	1.9	0.6	1.7	-1.9	1.9
Locomotion distance, session 3	2.7	2.9	4.2	-1.7	1.7	-1.7	-1.5	2.1	-2.1	-2.0	1.7	-1.7	1.2	-1.2	-0.8	2.0	-2.0	-1.7	1.7	-1.7	-1.7	-1.7	1.8	-1.8
Locomotion velocity, NPP test	2.7	3.8	8.5	-1.5	2.1	-2.1	-1.4	1.5	-1.5	-2.2	2.1	-2.1	2.9	-2.9	0.8	2.0	-2.0	-1.3	1.9	-1.9	-2.1	-1.9	1.9	-1.9
Pavlov. Cond. lever-magazine prob. diff.	2.7	3.4	6.3	-2.4	1.9	-1.9	-2.5	2.2	-2.2	-1.9	1.8	-1.8	-0.8	0.7	0.7	2.1	-2.1	-2.5	1.8	-1.8	-0.3	-1.8	1.7	-1.7
Condit. Reinf. inactive responses	2.6	3.1	5.2	-1.8	2.0	-2.0	-1.4	1.7	-1.7	-2.0	1.7	-1.7	2.1	-2.1	-0.8	1.8	-1.8	-1.4	1.7	-1.7	-2.3	-1.8	1.4	-1.4
Pavlov. Cond. index score	2.6	3.3	6.4	-2.4	1.8	-1.8	-2.4	2.2	-2.2	-1.9	1.8	-1.8	-0.8	0.8	0.8	2.0	-2.0	-2.5	1.8	-1.8	-0.2	-1.8	1.7	-1.7
Pavlov. Cond. latency score	2.6	3.3	6.8	-2.5	1.7	-1.7	-2.3	2.1	-2.1	-1.9	1.9	-1.9	-0.8	0.8	0.8	2.0	-2.0	-2.6	1.9	-1.9	-0.2	-1.7	1.8	-1.8
Seeking ratio, punishment vs. effort	2.6	3.2	8.0	-1.5	2.2	-2.2	-2.8	2.5	-2.5	-2.1	1.4	-1.4	0.0	-0.1	0.3	1.7	-1.7	-2.1	1.4	-1.4	-0.9	-1.9	2.1	-2.1
Left kidney weight	2.5	7.2	11.3	1.9	-3.3	3.3	3.4	-2.8	2.8	2.4	-2.8	2.8	-1.1	1.1	0.9	-2.8	2.8	2.9	-2.8	2.8	2.3	3.2	-2.9	3.0
Time in familiar zone, hab. session 1	2.5	2.4	5.8	-1.5	1.8	-1.8	-1.2	1.6	-1.6	-1.6	1.4	-1.4	1.3	-1.3	-2.4	1.4	-1.4	-1.1	1.3	-1.3	-2.3	-1.5	1.1	-1.1
Mg content in liver	2.4	2.4	4.2	-2.0	1.7	-1.8	-1.6	1.4	-1.3	-1.5	1.6	-1.6	-0.5	0.4	1.2	1.7	-1.7	-2.1	1.8	-1.8	0.0	-1.6	1.8	-1.8
Right kidney weight	2.3	6.7	9.8	1.5	-2.9	2.9	3.1	-3.0	3.0	2.7	-2.5	2.5	-1.3	1.4	1.1	-2.9	2.9	2.7	-2.5	2.5	2.4	2.9	-2.9	2.9
Pavlov. Cond. lever contacts	2.3	2.7	4.8	-2.2	1.5	-1.5	-2.0	1.9	-1.9	-1.9	1.7	-1.7	-0.2	0.1	1.6	1.8	-1.8	-2.1	1.7	-1.7	-0.1	-1.4	1.5	-1.5
Time >=10cm from walls, locomotor time 1	2.3	2.3	4.9	1.1	-1.4	1.4	1.7	-2.2	2.2	1.8	-1.5	1.5	-0.2	0.2	2.1	-1.3	1.3	1.7	-1.2	1.2	1.7	1.4	-1.5	1.4
Length with tail	2.2	8.2	13.0	2.8	-3.6	3.6	2.4	-2.4	2.4	2.5	-2.9	2.9	-2.9	2.9	1.8	-3.1	3.1	2.4	-2.8	2.8	3.6	3.3	-2.5	2.5
Intermittent access standard deviation	2.2	2.3	3.4	1.2	-1.7	1.7	1.7	-1.6	1.6	1.7	-1.6	1.6	-0.7	0.7	-0.5	-1.7	1.7	1.7	-1.7	1.7	0.9	1.5	-1.8	1.8
Short access day 10 total locomotion	2.2	2.4	5.0	0.5	-1.2	1.1	0.6	-1.8	1.8	2.2	-1.6	1.6	-2.1	2.1	1.6	-1.5	1.5	0.9	-1.5	1.5	2.2	1.0	-1.2	1.2
Stereotopy head waving duration, day 3	2.2	2.7	5.5	2.3	-1.6	1.5	0.8	-1.3	1.3	1.8	-1.6	1.6	-2.3	2.3	0.4	-1.9	1.9	1.1	-1.7	1.7	2.0	1.6	-1.0	1.0
Incentive salience index mean	2.2	2.7	4.7	-1.7	1.7	-1.7	-2.2	2.1	-2.1	-2.1	1.6	-1.6	0.4	-0.4	0.1	2.0	-2.0	-1.9	1.5	-1.5	-0.8	-1.6	1.6	-1.6
Bone: apparent density	2.2	3.7	7.6	-1.5	2.2	-2.1	-1.2	1.2	-1.2	-1.7	2.1	-2.1	2.8	-2.8	-1.2	2.0	-2.0	-1.2	2.0	-2.0	-2.6	-2.1	1.7	-1.7
Bone: final force	2.2	3.6	8.6	1.0	-2.5	2.5	2.9	-2.3	2.3	1.9	-1.5	1.5	0.3	-0.2	0.4	-1.8	1.8	2.3	-1.5	1.5	1.0	2.3	-2.6	2.5
Condit. Reinf. active-inactive response ratio	2.1	2.2	4.8	1.1	-1.7	1.7	1.2	-1.2	1.2	1.4	-1.5	1.5	-2.2	2.2	0.6	-1.5	1.5	0.9	-1.5	1.5	2.0	1.7	-1.1	1.1
One hour access (0.3 mA shock)	2.1	2.5	4.4	-2.1	1.4	-1.4	-0.8	0.9	-0.9	-1.2	1.9	-1.9	1.5	-1.5	-0.0	1.8	-1.8	-1.5	2.0	-2.0	-1.5	-2.0	1.6	-1.6
Distance traveled after self-admin	2.0	2.2	5.1	0.7	-1.2	1.2	1.6	-2.3	2.3	2.2	-1.5	1.5	-1.3	1.3	0.4	-1.5	1.5	1.3	-1.5	1.5	1.5	1.2	-1.4	1.4
Co content in liver	2.0	2.4	3.8	1.7	-1.7	1.7	1.8	-1.7	1.7	1.5	-1.7	1.7	-0.1	0.2	-0.1	-1.7	1.7	1.9	-1.7	1.7	0.8	1.6	-1.8	1.8
Locomotion velocity, hab. session 2	1.9	2.6	5.4	-2.3	1.5	-1.5	-0.6	0.9	-0.9	-1.4	1.9	-1.9	2.2	-2.2	0.5	1.8	-1.8	-1.3	1.8	-1.8	-1.6	-1.7	1.4	-1.4
Bone: connectivity density	1.9	2.9	7.3	-1.3	2.2	-2.2	-1.2	0.7	-0.7	-1.4	1.8	-1.8	2.7	-2.7	-0.3	1.5	-1.5	-0.9	1.8	-1.8	-2.1	-2.1	1.3	-1.4
Bone: final moment	1.9	3.2	7.0	1.1	-2.3	2.3	2.6	-2.0	2.0	1.7	-1.5	1.5	0.1	-0.0	0.3	-1.8	1.8	2.1	-1.5	1.5	1.0	2.2	-2.4	2.4
Delta distance traveled before/after self-admin	1.9	2.0	5.9	1.5	-1.3	1.3	0.9	-0.8	0.7	1.5	-1.4	1.4	-2.4	2.4	-1.4	-1.6	1.6	0.7	-1.4	1.4	1.3	1.2	-1.0	1.1
Time >=10cm from walls, locomotor time 2	1.9	2.0	3.3	1.0	-1.4	1.3	1.0	-1.3	1.3	1.6	-1.6	1.6	-0.9	0.9	1.7	-1.6	1.6	1.5	-1.3	1.3	1.8	1.4	-1.5	1.5
Reaction time premature initiations	1.8	2.6	3.9	1.5	-1.7	1.7	1.5	-1.5	1.5	1.7	-1.9	1.9	-0.4	0.4	0.7	-1.9	1.9	2.0	-1.7	1.7	1.2	1.8	-1.8	1.8
Intermitt. access day 15 inactive lever presses	1.8	2.0	3.2	1.1	-1.8	1.8	1.6	-1.3	1.3	1.4	-1.5	1.5	-1.3	1.3	-0.1	-1.3	1.3	1.1	-1.6	1.6	1.3	1.7	-1.4	1.4
Bone: trabecular thickness	1.8	2.2	5.4	-1.3	1.7	-1.6	-0.9	1.0	-1.0	-1.4	1.6	-1.6	2.3	-2.3	-0.8	1.3	-1.3	-0.9	1.6	-1.6	-2.2	-1.4	1.1	-1.1
Total locomotion distance, NPP test	1.7	2.4	6.0	-1.0	1.7	-1.7	-1.1	1.2	-1.2	-1.8	1.6	-1.6	2.4	-2.5	0.7	1.5	-1.5	-0.9	1.4	-1.4	-1.7	-1.4	1.5	-1.5
Pavlov. Cond. response bias	1.7	2.1	4.9	-1.7	1.6	-1.6	-2.2	1.9	-1.9	-1.6	1.2	-1.2	-0.9	0.8	0.7	1.6	-1.6	-1.9	1.2	-1.2	-0.0	-1.5	1.2	-1.3
Se content in liver	1.7	2.0	4.8	-1.2	1.0	-1.0	-2.0	1.8	-1.8	-1.2	0.9	-0.9	-2.0	2.0	0.5	1.2	-1.2	-2.2	0.9	-0.9	0.7	-1.2	1.7	-1.7
Length without tail	1.6	3.4	5.9	1.4	-2.4	2.4	2.0	-1.9	2.0	1.3	-1.8	1.8	0.3	-0.3	2.1	-1.7	1.7	2.2	-1.7	1.7	1.6	2.2	-2.1	2.2
Locomotor activity	1.6	2.6	5.9	1.5	-1.8	1.8	1.0	-1.1	1.1	1.8	-1.7	1.7	-2.4	2.4	0.4	-1.6	1.6	0.8	-1.7	1.7	2.0	1.7	-1.3	1.3
Intermitt. access escalation Index	1.6	1.5	2.7	-1.1	1.4	-1.4	-0.9	0.7	-0.7	-1.2	1.4	-1.4	1.0	-1.0	0.0	1.3	-1.3	-1.2	1.4	-1.4	-0.9	-1.7	1.2	-1.2
Locomotion distance, session 2	1.6	2.3	3.9	-1.4	1.2	-1.2	-1.2	1.7	-1.7	-2.0	1.7	-1.7	1.7	-1.8	0.4	1.8	-1.8	-1.3	1.5	-1.5	-1.4	-1.3	1.5	-1.5
Bone: maximum force	1.6	2.7	5.8	1.3	-2.2	2.2	2.4	-1.8	1.8	1.6	-1.4	1.4	-0.1	0.1	0.3	-1.5	1.5	1.9	-1.4	1.4	1.1	2.2	-2.0	2.0
Times rat made contact with spout	1.5	1.7	7.1	-0.6	1.3	-1.3	-1.1	1.5	-1.5	-1.1	1.1	-1.1	0.6	-0.6	-2.7	1.2	-1.2	-1.1	1.0	-1.0	-1.8	-1.1	1.3	-1.3
Delay discounting total patch changes 0 sec	1.5	2.4	5.1	2.3	-1.4	1.4	1.1	-1.1	1.1	1.6	-1.7	1.7	-0.8	0.8	-1.5	-2.1	2.1	1.8	-1.7	1.7	0.6	1.6	-1.5	1.5
Reaction time mean minus median AUC	1.5	1.9	3.0	-1.3	1.3	-1.3	-1.5	1.6	-1.6	-1.7	1.5	-1.5	0.4	-0.4	0.6	1.7	-1.7	-1.7	1.4	-1.4	-0.6	-1.0	1.5	-1.5
Total locomotion distance, hab. session 2	1.5	2.0	5.0	-2.0	1.3	-1.3	-0.3	0.6	-0.6	-1.1	1.7	-1.7	2.2	-2.2	0.5	1.5	-1.5	-1.0	1.5	-1.5	-1.6	-1.4	1.1	-1.1
Total zone transitions, NPP test	1.5	2.1	3.0	-1.7	1.6	-1.6	-0.9	1.2	-1.2	-1.6	1.5	-1.5	1.6	-1.7	0.4	1.6	-1.6	-1.3	1.3	-1.3	-1.4	-1.5	1.7	-1.7
Time to tail flick, vehicle, before self-admin	1.5	1.5	3.9	-2.0	0.6	-0.5	0.2	0.3	-0.3	-0.4	1.6	-1.6	1.9	-1.9	0.2	1.4	-1.4	-0.8	1.6	-1.6	-1.3	-1.0	0.6	-0.6
Delay disc. indifference point, 4s delay	1.5	1.6	3.4	1.0	-1.5	1.5	0.8	-0.7	0.7	1.2	-1.3	1.3	-1.8	1.8	0.1	-1.3	1.3	0.7	-1.2	1.2	1.5	1.1	-1.4	1.4
BMI with tail	1.4	4.7	8.1	1.5	-2.5	2.5	2.8	-2.4	2.4	2.1	-2.2	2.2	0.3	-0.3	0.9	-1.9	1.9	2.8	-2.2	2.2	1.3	2.7	-2.8	2.8
Indifference point 0 sec	1.4	2.3	5.2	2.3	-1.4	1.4	1.1	-1.2	1.2	1.6	-1.7	1.7	-0.8	0.8	-1.3	-2.1	2.1	1.8	-1.7	1.7	0.7	1.5	-1.4	1.4
Incentive Sensitization - Breakpoint	1.4	1.4	2.4	-1.3	1.1	-1.1	-0.3	0.4	-0.4	-0.6	1.4	-1.4	1.3	-1.2	-1.1	1.4	-1.4	-1.1	1.4	-1.4	-1.5	-1.6	0.9	-1.0
Locomotion distance, session 1	1.4	1.8	2.6	-1.1	1.1	-1.0	-0.8	1.4	-1.4	-1.5	1.6	-1.6	1.5	-1.5	-0.7	1.5	-1.5	-1.2	1.3	-1.3	-1.6	-1.3	1.3	-1.3
Bone: maximum moment	1.4	2.4	4.6	1.4	-2.0	2.0	2.1	-1.7	1.7	1.5	-1.5	1.5	-0.4	0.4	0.3	-1.5	1.5	1.8	-1.5	1.5	1.1	2.1	-1.9	1.9
Liver weight, right	1.3	2.2	5.6	1.2	-1.9	1.9	1.2	-1.2	1.2	1.6	-1.1	1.1	-2.3	2.3	1.6	-1.3	1.3	0.5	-1.0	1.0	2.4	1.6	-1.0	1.0
Condit. Reinf. active minus inactive responses	1.3	1.6	3.7	1.1	-1.4	1.4	0.9	-1.0	1.0	1.2	-1.4	1.4	-1.9	1.9	-0.1	-1.2	1.2	0.8	-1.4	1.4	1.5	1.2	-1.0	1.0
Cocaine induced anxiety	1.3	1.5	2.6	-1.6	1.5	-1.5	-0.7	0.4	-0.4	-0.8	1.4	-1.4	1.6	-1.6	0.7	1.4	-1.4	-0.9	1.3	-1.3	-1.1	-1.2	1.0	-1.0
Short access day 1 locomotion	1.3	1.3	2.7	-1.5	1.6	-1.6	-1.4	0.8	-0.8	-0.9	1.1	-1.1	0.6	-0.6	0.6	1.3	-1.3	-1.2	1.2	-1.2	-0.7	-1.5	1.2	-1.2
Compulsive drug intake	1.3	1.3	2.8	-1.4	1.2	-1.3	-0.7	0.0	-0.0	-0.3	1.5	-1.5	0.7	-0.7	0.9	1.4	-1.4	-1.4	1.4	-1.4	-0.4	-1.7	1.2	-1.2
Stereotopy head waving bouts, day 3	1.3	1.6	3.0	1.5	-1.4	1.4	0.8	-1.2	1.2	1.5	-1.2	1.2	-1.6	1.6	1.1	-1.2	1.2	0.8	-1.2	1.2	1.7	1.4	-0.9	0.9
Condit. Reinf. active responses	1.3	1.6	3.3	-1.0	1.4	-1.4	-1.7	1.8	-1.8	-1.7	1.0	-1.0	0.6	-0.6	-1.0	1.4	-1.4	-1.2	1.0	-1.0	-1.2	-1.3	1.0	-1.1
Pavlov. Cond. magazine entry latency	1.3	1.7	3.8	-1.5	1.3	-1.3	-1.9	1.7	-1.7	-1.2	1.1	-1.1	-1.4	1.3	0.0	1.3	-1.3	-2.0	1.1	-1.1	0.1	-1.3	1.2	-1.2
Epididymis fat weight	1.2	2.9	7.0	1.8	-1.6	1.7	2.4	-1.5	1.5	1.0	-1.4	1.4	1.8	-1.7	-2.2	-1.3	1.3	2.6	-1.4	1.4	-0.9	1.6	-2.1	2.1
Locomotor testing rearing	1.2	1.9	2.7	1.6	-1.3	1.3	1.3	-1.6	1.6	1.4	-1.5	1.5	-0.8	0.8	1.1	-1.6	1.6	1.3	-1.5	1.5	1.4	1.5	-1.2	1.2
Social response proportion	1.2	1.3	3.1	1.3	-0.8	0.8	0.2	-0.7	0.7	0.7	-1.3	1.3	-1.5	1.5	1.4	-1.3	1.3	1.0	-1.2	1.2	1.8	0.9	-1.0	0.9
Baseline Anxiety	1.2	1.3	2.9	0.9	-1.0	1.0	0.5	-0.7	0.7	1.0	-1.3	1.3	-1.7	1.7	0.2	-1.3	1.3	0.8	-1.3	1.3	1.4	0.9	-1.1	1.1
Progressive ratio test 2 breakpoint	1.2	1.4	2.3	-1.2	1.4	-1.3	-0.9	1.0	-1.0	-1.2	1.2	-1.2	1.1	-1.1	-1.0	1.2	-1.2	-1.0	1.2	-1.2	-1.5	-1.5	1.1	-1.1
Delta ambulatory time before/after self-admin	1.2	1.3	4.3	0.9	-1.1	1.1	0.7	-0.7	0.7	1.4	-1.0	1.0	-2.1	2.1	-0.8	-1.2	1.2	0.4	-1.0	1.0	1.2	0.9	-0.8	0.8
Bouts of movement, locomotor time 1	1.2	1.3	2.2	-1.2	1.4	-1.4	-1.2	0.9	-0.9	-0.6	1.3	-1.3	0.6	-0.6	-0.2	1.5	-1.5	-1.2	1.2	-1.2	-1.0	-1.3	1.2	-1.2
Incentive Sensitization - Responses	1.1	1.1	2.1	-1.2	1.0	-1.0	-0.3	0.4	-0.4	-0.6	1.3	-1.3	1.0	-0.9	-1.2	1.2	-1.2	-1.1	1.3	-1.3	-1.4	-1.5	0.9	-0.9
Delta time in closed arm before/after self-admin	1.1	1.1	2.2	0.5	-0.8	0.8	0.8	-1.5	1.5	1.0	-1.1	1.1	-0.4	0.4	1.3	-1.1	1.1	1.1	-1.1	1.1	1.2	1.1	-0.9	0.9
Delay disc. indifference point, 2s delay	1.1	1.2	4.5	0.6	-1.4	1.4	0.3	0.1	-0.1	0.5	-1.0	1.0	-2.1	2.1	0.7	-1.0	1.0	0.3	-1.0	1.0	1.7	1.0	-0.7	0.7
Seeking ratio, delayed vs. immediate footshock	1.1	1.3	3.4	0.4	-1.2	1.2	1.4	-1.5	1.4	1.8	-0.9	0.9	-1.4	1.4	-1.0	-1.0	1.0	0.6	-0.7	0.7	0.8	0.5	-1.3	1.2
Heart weight	1.0	1.4	5.0	0.9	-1.0	1.0	0.5	-0.8	0.8	1.0	-1.3	1.3	-2.2	2.2	-0.2	-1.3	1.3	0.6	-1.3	1.3	1.6	0.6	-0.6	0.6
Liver weight, left	1.0	1.5	2.6	1.2	-1.1	1.1	1.0	-1.6	1.6	1.5	-1.3	1.3	-0.7	0.7	1.2	-1.2	1.2	1.3	-1.3	1.3	1.3	1.3	-1.3	1.3
Delay discounting total patch changes 12 sec	1.0	1.4	2.6	0.7	-1.3	1.3	1.3	-1.0	1.0	1.3	-1.1	1.1	-0.6	0.6	-1.4	-1.6	1.6	1.2	-1.3	1.3	0.3	1.2	-1.3	1.3
Reaction time mean minus median	1.0	1.3	2.5	-1.5	0.9	-0.9	-0.9	1.1	-1.1	-1.2	1.4	-1.4	0.1	-0.2	0.5	1.5	-1.5	-1.6	1.2	-1.2	-0.4	-0.9	1.4	-1.4
Reaction time mean	1.0	1.4	3.2	-1.0	1.2	-1.2	-1.4	1.0	-1.0	-1.4	1.3	-1.3	0.7	-0.7	1.8	1.3	-1.3	-1.3	1.2	-1.2	-0.2	-0.8	1.3	-1.3
Reaction time mean AUC	1.0	1.3	2.7	-1.0	1.2	-1.2	-1.4	1.0	-1.0	-1.5	1.3	-1.3	0.7	-0.7	1.7	1.3	-1.3	-1.2	1.1	-1.1	-0.2	-0.8	1.2	-1.2
Social responses	1.0	1.3	3.2	1.0	-1.2	1.2	0.5	-0.6	0.6	0.8	-1.3	1.3	-1.8	1.8	0.5	-1.2	1.2	0.7	-1.3	1.3	1.6	0.9	-1.0	1.0
Cocaine response after cond. corrected	1.0	1.2	4.0	-1.6	0.7	-0.7	0.0	0.3	-0.3	-0.7	1.3	-1.3	2.0	-2.0	1.2	0.9	-0.9	-0.4	1.3	-1.3	-0.9	-0.8	0.1	-0.2
Intermittent access day 1 total infusions	1.0	1.1	3.4	-0.8	1.2	-1.2	-1.3	1.7	-1.7	-1.9	0.9	-0.9	0.4	-0.5	-0.2	0.9	-0.9	-0.9	0.9	-0.9	-0.8	-1.0	1.0	-1.0
Number of responses in last shaping day	1.0	1.0	4.7	0.3	-0.7	0.7	-0.2	0.1	-0.1	0.3	-1.0	1.0	-2.2	2.2	1.2	-0.8	0.8	-0.1	-1.0	1.0	1.8	0.8	-0.3	0.3
Condit. Reinf. active minus inactive responses	1.0	1.1	3.0	-0.6	1.0	-1.0	-1.7	1.7	-1.7	-1.3	0.7	-0.7	-0.5	0.5	-1.2	1.0	-1.0	-1.2	0.7	-0.7	-0.6	-0.9	0.9	-0.9
Bone: cortical porosity	1.0	1.0	7.0	0.9	-0.6	0.6	-0.7	0.7	-0.8	0.2	-0.6	0.6	-2.7	2.6	-1.0	-0.6	0.6	-0.5	-0.6	0.6	1.0	0.5	0.1	-0.1
Delta time to tail flick, test, before/after SA	1.0	0.9	1.8	-0.4	1.3	-1.3	-1.1	0.8	-0.8	-1.3	0.7	-0.7	1.3	-1.3	-0.3	0.9	-0.9	-0.5	0.6	-0.6	-1.1	-0.8	1.0	-1.0
Glucose	0.9	1.3	11.1	-0.4	0.9	-0.9	-1.9	0.7	-0.7	-0.9	0.4	-0.4	-1.3	1.2	3.3	0.8	-0.8	-1.1	0.4	-0.4	1.6	-0.3	0.7	-0.7
Delay discounting total patch changes 6 sec	0.9	1.4	3.1	1.8	-1.2	1.2	1.0	-0.8	0.8	1.0	-1.2	1.2	-0.3	0.4	-1.5	-1.6	1.6	1.5	-1.3	1.3	0.2	1.2	-1.2	1.2
Locomotor testing distance	0.9	1.4	2.2	1.0	-1.2	1.2	0.8	-1.0	1.0	1.4	-1.3	1.3	-1.5	1.5	0.5	-1.3	1.3	0.8	-1.4	1.4	1.4	1.2	-1.0	1.0
Intermitt. access day 1 inactive lever presses	0.9	1.0	2.9	0.3	-0.9	0.8	0.8	-1.6	1.6	1.3	-0.8	0.8	-0.5	0.6	1.7	-0.7	0.7	0.7	-0.8	0.8	1.3	0.8	-0.9	0.9
Stereotopy head waving duration, day 7	0.9	1.1	2.8	1.0	-1.5	1.5	1.0	-0.6	0.5	0.9	-0.8	0.8	-1.6	1.7	-0.8	-1.0	1.0	0.4	-0.9	0.9	1.0	1.1	-0.6	0.6
Pavlov. Cond. magazine entry number	0.9	1.1	2.4	1.5	-1.2	1.3	1.6	-1.3	1.3	0.9	-0.8	0.8	1.1	-1.1	0.0	-1.1	1.1	1.6	-0.8	0.8	0.0	1.3	-0.6	0.7
Bone: endosteal perimeter	0.9	1.8	7.1	0.2	-0.9	0.8	0.4	-1.2	1.2	1.2	-1.2	1.2	-2.0	2.0	2.7	-1.1	1.1	0.5	-1.1	1.1	2.5	0.9	-1.0	1.0
Bone: minimum diameter	0.9	1.6	5.1	-0.2	-1.0	1.0	0.9	-1.2	1.2	1.1	-1.2	1.2	-1.6	1.6	2.3	-0.9	0.9	0.7	-1.2	1.2	2.2	1.2	-1.1	1.1
Ambulatory time after self-admin	0.9	1.0	2.1	0.5	-0.8	0.8	1.1	-1.4	1.4	1.4	-1.0	1.0	-1.2	1.2	-0.1	-1.1	1.1	0.7	-1.0	1.0	1.1	0.8	-0.8	0.8
Locomotion in novel chamber post-restriction	0.9	1.0	1.8	1.1	-1.0	1.0	1.0	-1.1	1.1	1.0	-1.2	1.2	-0.2	0.2	0.1	-1.3	1.3	1.3	-1.1	1.1	0.7	0.7	-1.1	1.2
Parametrial fat weight	0.8	1.5	4.4	0.5	-1.6	1.6	2.1	-1.2	1.2	1.0	-0.9	0.9	1.4	-1.3	0.1	-0.6	0.6	1.6	-1.0	1.0	-0.1	1.6	-1.5	1.5
Conditioned locomotion	0.8	0.9	2.3	1.0	-0.9	0.9	0.9	-1.1	1.1	1.1	-1.0	1.0	0.0	-0.0	1.5	-0.8	0.8	1.0	-1.0	1.0	1.0	1.2	-0.7	0.7
Bone: cortical porosity	0.8	0.9	5.0	0.8	-0.4	0.4	-0.7	0.9	-0.9	0.0	-0.6	0.6	-2.2	2.2	-1.7	-0.4	0.4	-0.4	-0.6	0.6	0.5	0.3	0.2	-0.1
Bone: periosteal perimeter	0.8	1.3	3.4	-0.0	-1.2	1.2	0.9	-1.1	1.1	1.1	-1.0	1.0	-1.6	1.6	1.5	-1.0	1.0	0.6	-1.0	1.0	1.8	1.1	-1.1	1.1
Delay disc. indifference point, 24s delay	0.8	0.8	2.3	1.1	-0.9	0.9	-0.2	0.3	-0.4	0.6	-0.9	0.9	-1.5	1.5	-0.7	-0.9	0.9	0.4	-0.8	0.8	0.8	0.8	-0.8	0.8
Total resting periods, locomotor time 1	0.8	0.9	1.5	-1.1	1.2	-1.2	-1.1	0.8	-0.8	-0.4	1.1	-1.1	0.4	-0.4	0.0	1.2	-1.2	-1.0	1.0	-1.0	-0.7	-1.0	1.0	-1.0
Latency to leave start box in cocaine runway, F	0.8	0.8	3.1	-1.8	0.7	-0.7	-0.4	0.5	-0.5	-0.8	1.1	-1.1	0.5	-0.6	0.8	1.0	-1.0	-0.9	1.1	-1.1	-0.3	-0.8	1.0	-1.0
K content in liver	0.8	0.8	1.9	-1.2	0.8	-0.8	-0.6	0.7	-0.7	-0.8	1.1	-1.1	0.5	-0.5	0.5	1.2	-1.2	-1.0	1.4	-1.4	-0.5	-0.8	0.8	-0.8
Intraocular pressure	0.7	1.0	3.0	-1.0	1.3	-1.3	-0.6	0.6	-0.6	-0.6	0.9	-0.9	1.7	-1.7	-0.8	0.7	-0.7	-0.2	1.0	-1.0	-1.5	-1.1	0.6	-0.6
Soleus weight	0.7	2.0	14.1	0.2	-0.9	0.9	0.5	-1.1	1.1	0.8	-0.7	0.7	-2.1	2.1	3.8	-1.1	1.1	0.3	-0.6	0.6	3.0	1.0	-0.6	0.6
Reaction time number correct	0.7	1.0	2.2	1.5	-0.8	0.8	0.8	-1.1	1.1	1.3	-1.2	1.2	0.1	-0.0	-0.6	-1.1	1.1	1.5	-1.0	1.0	0.2	0.8	-1.1	1.1
Reaction time trials correct on left	0.7	1.0	2.2	1.5	-0.8	0.8	0.8	-1.1	1.1	1.3	-1.2	1.2	0.1	-0.0	-0.6	-1.1	1.1	1.5	-1.0	1.0	0.2	0.8	-1.1	1.1
Reaction time trials on left	0.7	1.0	2.3	1.5	-0.9	0.9	0.8	-1.1	1.1	1.3	-1.2	1.2	-0.0	0.0	-0.6	-1.2	1.2	1.5	-1.1	1.1	0.3	0.8	-1.1	1.1
Reaction time premature initiation rate	0.7	1.0	1.6	0.9	-1.2	1.2	1.0	-0.8	0.8	0.9	-1.1	1.1	-0.3	0.3	1.0	-1.2	1.2	1.1	-1.0	1.0	1.0	1.3	-1.0	1.1
Std. dev. reaction times	0.7	1.0	2.3	-0.9	0.6	-0.7	-1.2	1.1	-1.1	-1.0	1.0	-1.0	-0.6	0.6	0.9	1.1	-1.1	-1.5	0.8	-0.8	0.2	-0.6	1.3	-1.3
Reaction time trials completed	0.7	1.0	2.3	1.5	-0.9	0.9	0.8	-1.1	1.1	1.3	-1.2	1.2	-0.0	0.0	-0.6	-1.2	1.2	1.5	-1.1	1.1	0.3	0.8	-1.1	1.1
Intermittent access intake escalation 2	0.7	0.7	1.7	-0.9	0.7	-0.7	-0.7	0.6	-0.6	-0.5	1.1	-1.1	-0.0	0.0	0.1	1.0	-1.0	-1.3	1.1	-1.1	-0.3	-1.0	1.2	-1.2
Progressive ratio test 2 active lever presses	0.7	0.8	1.4	-0.9	1.0	-1.0	-0.6	0.7	-0.7	-0.9	0.9	-0.9	0.8	-0.8	-0.7	0.9	-0.9	-0.7	0.9	-0.9	-1.0	-1.2	0.9	-0.9
Short access total locomotion	0.7	0.7	1.7	0.3	-0.4	0.3	-0.0	-0.9	0.9	0.9	-1.0	1.0	-1.0	1.0	1.3	-0.8	0.8	0.6	-1.0	1.0	1.3	0.5	-0.6	0.6
Bone: cortical tissue density	0.7	0.9	2.0	0.9	-0.8	0.8	1.4	-1.3	1.3	1.1	-0.8	0.8	0.6	-0.6	-0.7	-0.8	0.8	1.3	-0.8	0.8	-0.2	0.7	-1.0	1.0
Bone: stiffness	0.7	1.1	3.4	-0.1	-1.0	1.0	1.8	-1.5	1.5	1.1	-0.6	0.6	0.8	-0.7	0.1	-0.7	0.7	1.3	-0.6	0.6	0.1	1.0	-1.6	1.5
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	2.5	1.1	0.9	-0.9	-1.6	1.5	-1.4	-1.1	0.3	-0.3	-0.3	0.3	-0.3	0.3	-0.3	-0.6	0.2	-0.2	-0.2	-0.5	1.1	-1.1
Mn content in liver	0.7	0.8	5.5	-1.0	0.3	-0.4	-0.9	0.4	-0.4	-0.3	0.2	-0.2	-1.3	1.2	2.3	0.6	-0.6	-0.9	0.5	-0.5	1.5	-0.4	0.5	-0.5
Std. dev. time between licks in bursts	0.6	0.8	4.6	0.2	-0.2	0.2	-0.4	-0.3	0.3	0.4	-0.4	0.4	-1.7	1.7	2.2	-0.4	0.4	-0.4	-0.4	0.4	1.8	0.4	0.0	-0.0
Delay discounting total patch changes 24 sec	0.6	0.7	3.6	-0.1	0.6	-0.5	-0.4	0.8	-0.8	-0.8	0.6	-0.6	1.5	-1.5	-1.9	0.4	-0.4	0.0	0.3	-0.3	-1.8	-0.3	0.4	-0.4
Median of all reaction times	0.6	0.9	3.8	-0.5	0.9	-0.9	-1.2	0.7	-0.7	-1.1	0.9	-0.9	0.7	-0.8	1.9	0.9	-0.9	-0.8	0.8	-0.8	0.0	-0.5	0.9	-0.9
Reaction time omissions	0.6	0.8	2.0	-1.4	0.9	-0.9	-0.9	0.8	-0.8	-0.8	1.0	-1.0	0.4	-0.5	1.0	1.0	-1.0	-1.1	0.8	-0.8	-0.3	-0.7	0.9	-0.9
Reaction time trials AUC	0.6	0.9	2.0	1.4	-0.8	0.8	0.8	-1.1	1.1	1.2	-1.1	1.1	0.2	-0.1	-0.5	-1.1	1.1	1.4	-0.9	0.9	0.2	0.7	-1.0	1.1
Short access day 1 total infusions	0.6	0.6	2.7	-0.1	0.6	-0.6	-1.6	1.6	-1.6	-1.3	-0.1	0.1	-1.0	0.9	0.6	-0.1	0.1	-0.5	-0.1	0.1	0.5	-0.1	0.5	-0.5
Locomotion velocity, session 8	0.6	0.8	3.9	-0.4	0.2	-0.3	-1.1	0.7	-0.7	-0.5	0.5	-0.5	-1.3	1.3	2.0	0.6	-0.6	-1.2	0.3	-0.3	1.2	-0.2	1.0	-1.0
Time in novel zone, hab. session 2	0.6	0.6	5.4	2.3	-0.6	0.6	-0.2	-0.0	0.0	0.2	-0.6	0.6	-0.8	0.8	-0.0	-0.8	0.8	0.4	-0.7	0.7	0.7	0.6	0.3	-0.3
Pavlov. Cond. change in total contacts	0.6	0.6	2.0	-1.4	0.2	-0.2	-0.9	1.1	-1.1	-0.6	0.6	-0.6	-1.3	1.3	0.2	0.8	-0.8	-1.3	0.5	-0.5	0.4	-0.5	0.3	-0.3
Bone: cortical apparent density	0.6	0.8	2.1	0.7	-0.7	0.8	1.5	-1.3	1.3	1.1	-0.7	0.7	0.8	-0.8	-0.8	-0.7	0.7	1.3	-0.7	0.7	-0.3	0.7	-1.0	1.0
Bone: trabecular tissue density	0.6	0.9	3.3	0.9	-1.2	1.2	0.6	-0.4	0.4	1.0	-0.8	0.8	-1.8	1.8	-0.8	-1.0	1.0	0.2	-0.7	0.7	0.9	0.7	-0.6	0.6
Time in open arm before self-admin	0.6	0.7	1.6	0.3	0.7	-0.7	-1.3	1.1	-1.1	-0.6	0.6	-0.6	-0.7	0.7	-0.7	0.6	-0.6	-1.1	0.6	-0.6	-0.3	-0.8	1.2	-1.2
Change in fecal boli incidents, locomotor task	0.6	0.6	1.9	-0.3	-1.0	1.0	0.7	-0.7	0.7	0.9	-0.4	0.4	-1.1	1.1	1.4	-0.5	0.5	0.0	-0.3	0.3	1.3	0.6	-0.6	0.6
Fe content in liver	0.6	0.8	2.2	1.5	-0.8	0.8	0.8	-0.9	0.9	0.8	-0.8	0.8	0.3	-0.3	-1.0	-1.3	1.3	1.2	-0.6	0.6	-0.1	0.8	-0.7	0.7
Na content in liver	0.6	0.6	2.0	-1.4	0.5	-0.5	-0.3	0.6	-0.6	-0.5	1.0	-1.0	0.5	-0.5	-0.2	1.0	-1.0	-0.9	1.2	-1.2	-0.7	-0.7	0.4	-0.4
Sr content in liver	0.6	0.5	2.4	1.1	-0.6	0.6	0.0	-0.5	0.5	0.4	-0.6	0.6	-0.4	0.4	1.6	-0.6	0.6	0.8	-0.3	0.3	1.0	0.9	-0.8	0.8
Food consumed during 24 hour testing period	0.5	0.6	2.7	0.4	-0.8	0.8	0.9	-1.0	1.0	0.7	-0.6	0.6	0.3	-0.2	1.7	-0.6	0.6	0.8	-0.5	0.5	0.9	1.1	-0.6	0.6
Indifference point AUC	0.5	0.6	2.1	-0.2	-1.2	1.2	0.8	-0.3	0.3	0.8	-0.4	0.4	-1.4	1.4	-0.5	-0.6	0.6	-0.0	-0.5	0.5	0.7	0.9	-0.4	0.4
Delay discounting total patch changes 18 sec	0.5	0.7	3.4	0.4	-0.5	0.5	1.1	-0.6	0.6	0.6	-0.2	0.2	1.4	-1.4	-1.8	-0.5	0.5	1.1	-0.3	0.3	-1.2	0.5	-0.6	0.6
Delay discounting time to switch 0 sec	0.5	0.8	4.8	-0.0	-0.0	0.0	1.1	-1.1	1.1	0.1	-0.1	0.1	2.2	-2.2	0.3	0.0	-0.0	1.2	-0.3	0.3	-0.7	0.1	-0.6	0.6
Social time	0.5	0.6	4.6	-2.1	0.0	-0.1	0.2	-0.0	0.0	-0.2	0.7	-0.7	-0.2	0.2	1.9	0.8	-0.8	-1.0	0.6	-0.6	0.5	-0.4	0.3	-0.4
Short access day 1 total inactive lever presses	0.5	0.5	3.3	0.0	0.3	-0.3	-1.0	0.9	-0.9	-1.5	-0.2	0.2	-0.7	0.7	1.8	0.1	-0.1	-0.4	-0.2	0.2	0.9	0.4	0.4	-0.4
Locomotion velocity, session 1	0.5	0.6	1.4	0.2	0.5	-0.5	-1.1	1.2	-1.2	-0.8	0.5	-0.5	-0.8	0.8	-0.2	0.6	-0.6	-1.1	0.5	-0.5	0.0	-0.7	1.2	-1.1
Stereotopy head waving bouts, day 7	0.5	0.6	2.9	0.9	-1.1	1.1	0.4	-0.0	-0.0	0.5	-0.4	0.4	-1.7	1.7	-1.1	-0.5	0.5	-0.1	-0.3	0.3	0.7	0.7	-0.1	0.1
Total locomotion distance, hab. session 1	0.5	0.8	1.2	-1.1	1.0	-1.0	-0.6	0.5	-0.5	-0.7	1.1	-1.1	1.0	-1.0	0.3	0.9	-0.9	-0.8	0.9	-0.9	-0.9	-1.0	0.7	-0.7
Bone: cortical thickness	0.5	0.6	2.4	-0.3	-0.8	0.8	1.6	-0.9	0.9	0.7	-0.4	0.4	1.1	-1.0	-1.1	-0.3	0.3	0.9	-0.3	0.3	-0.7	0.4	-0.9	0.9
Breakpoint value in progressive ratio session	0.5	0.5	1.2	-0.5	1.1	-1.1	-0.8	0.5	-0.5	-0.6	0.9	-0.9	0.2	-0.2	0.2	0.7	-0.7	-0.8	0.9	-0.9	-0.3	-1.0	0.6	-0.6
Time in open arm after self-admin	0.5	0.6	1.6	0.5	0.9	-0.9	-1.1	1.0	-1.0	-0.6	0.3	-0.3	-1.1	1.1	-1.3	0.2	-0.2	-0.8	0.3	-0.3	-0.1	-0.7	0.9	-0.8
Delay discount hyperbolic model param	0.5	0.5	2.4	-0.7	1.0	-1.0	-0.0	-0.4	0.4	-0.3	0.6	-0.6	1.6	-1.6	0.4	0.5	-0.5	-0.0	0.4	-0.4	-0.9	-0.6	0.6	-0.6
Retroperitoneal fat weight	0.4	1.2	2.0	1.4	-1.1	1.1	1.0	-0.8	0.8	0.7	-1.4	1.4	-0.3	0.3	0.3	-1.1	1.1	1.4	-1.4	1.4	0.9	1.3	-1.0	1.1
Mean time between licks in bursts	0.4	0.5	3.3	-0.7	0.4	-0.4	-0.7	0.3	-0.3	-0.1	0.4	-0.4	-1.1	1.1	1.8	0.3	-0.3	-0.9	0.5	-0.5	0.9	-0.3	0.5	-0.5
Delay discounting water rate 12 sec	0.4	0.6	1.4	-0.6	0.7	-0.7	-0.5	0.6	-0.6	-0.6	0.8	-0.8	0.9	-0.9	-0.7	0.8	-0.8	-0.5	1.2	-1.2	-1.1	-0.8	0.5	-0.5
Light reinforcement 1	0.4	0.8	3.1	-0.8	-0.7	0.7	1.8	-1.5	1.5	0.9	-0.1	0.1	1.4	-1.4	0.1	-0.2	0.2	0.9	-0.2	0.2	-0.3	0.4	-0.7	0.7
Light reinforcement 2	0.4	0.5	1.5	0.1	-0.7	0.7	1.2	-1.1	1.1	0.4	-0.5	0.5	0.9	-0.9	0.8	-0.2	0.2	0.8	-0.8	0.8	0.3	0.9	-0.3	0.3
Pavlov. Cond. intertrial magazine entries	0.4	0.5	1.5	-1.2	0.7	-0.8	-0.6	0.6	-0.6	-0.3	0.7	-0.7	-0.7	0.7	0.5	0.6	-0.6	-1.1	0.7	-0.7	0.2	-1.2	0.6	-0.6
Pavlov. Cond. response bias	0.4	0.6	1.7	-0.6	0.7	-0.7	-0.7	1.1	-1.1	-0.9	0.6	-0.6	0.1	-0.1	-1.3	0.7	-0.7	-0.7	0.7	-0.7	-0.9	-0.5	0.6	-0.6
Intermittent access day 15 total infusions	0.4	0.5	0.7	-0.5	0.7	-0.6	-0.3	0.6	-0.6	-0.8	0.7	-0.7	0.6	-0.6	-0.8	0.6	-0.6	-0.6	0.7	-0.7	-0.9	-0.8	0.7	-0.7
Intermittent access day 15 total locomotion	0.4	0.5	1.2	0.8	-0.7	0.7	0.7	-0.9	0.9	1.1	-0.7	0.7	-0.2	0.2	0.1	-0.7	0.7	0.8	-0.7	0.7	0.5	0.7	-0.6	0.6
Locomotion velocity, session 2	0.4	0.5	1.9	-1.4	0.3	-0.3	-0.5	1.0	-1.0	-0.8	0.8	-0.8	-0.1	0.1	0.4	0.7	-0.7	-1.0	0.7	-0.7	-0.2	-0.5	0.6	-0.7
Total zone transitions, hab. session 1	0.4	0.6	1.7	-1.3	0.8	-0.8	-0.4	0.5	-0.5	-0.6	0.9	-0.9	0.6	-0.6	0.2	0.7	-0.7	-0.9	0.8	-0.8	-0.7	-0.9	0.7	-0.7
Total zone transitions, hab. session 2	0.4	0.5	2.5	-1.6	0.1	-0.1	0.7	-0.2	0.2	-0.2	0.7	-0.7	1.3	-1.3	0.5	0.6	-0.6	-0.2	0.6	-0.6	-0.7	-0.5	0.3	-0.3
Pavlov. Cond. intertrial magazine entries	0.4	0.5	2.7	0.8	0.5	-0.4	-0.0	0.0	-0.0	-0.5	-0.1	0.1	1.6	-1.6	-0.8	0.3	-0.3	0.6	-0.1	0.1	-1.1	-0.1	0.5	-0.4
Bone: cortical area	0.4	0.6	1.8	-0.3	-1.1	1.1	1.3	-0.9	0.9	0.8	-0.6	0.6	-0.4	0.5	0.3	-0.4	0.4	0.6	-0.7	0.7	0.7	1.0	-0.8	0.8
Bone: cortical thickness	0.4	0.7	3.0	-0.2	-1.1	1.2	1.7	-0.7	0.7	0.6	-0.3	0.3	0.8	-0.7	-1.3	-0.2	0.2	0.9	-0.4	0.4	-0.5	1.0	-1.0	1.0
Bone: post-yield work	0.4	0.6	2.7	0.8	-0.1	0.1	0.3	-1.2	1.2	0.8	-0.7	0.7	-0.5	0.5	1.6	-0.6	0.6	0.6	-0.7	0.7	1.1	0.5	-0.3	0.3
Bone: tissue strength	0.4	0.3	1.3	1.1	-1.0	1.0	0.7	-0.3	0.3	0.1	-0.3	0.3	0.4	-0.4	0.2	-0.3	0.3	0.7	-0.3	0.3	0.2	1.1	-0.5	0.5
Distance traveled before self-admin	0.4	0.4	2.3	-0.7	-0.1	0.1	0.8	-1.2	1.2	0.7	-0.1	0.1	0.9	-0.9	1.5	0.1	-0.1	0.5	-0.1	0.1	0.2	0.1	-0.3	0.3
Time to tail flick, vehicle, after self-admin	0.4	0.4	0.8	-0.0	0.7	-0.7	-0.8	0.5	-0.5	-0.4	0.7	-0.7	0.4	-0.4	0.8	0.7	-0.7	-0.7	0.6	-0.6	-0.2	-0.6	0.9	-0.9
Time to tail flick, test, before self-admin	0.4	0.4	0.8	-0.6	0.0	-0.0	0.4	0.2	-0.2	-0.1	0.9	-0.9	0.7	-0.7	-0.8	0.7	-0.7	-0.5	0.9	-0.9	-0.9	-0.5	0.4	-0.4
Delay discount exponential model param	0.4	0.4	1.7	-0.7	0.9	-0.9	0.0	-0.5	0.5	-0.1	0.5	-0.5	1.3	-1.3	0.5	0.4	-0.4	-0.0	0.3	-0.3	-0.7	-0.4	0.5	-0.5
Vertical activity count, locomotor time 1	0.4	0.4	1.3	0.3	-0.8	0.8	0.9	-0.6	0.6	0.7	-0.3	0.3	0.6	-0.5	-0.2	-0.6	0.6	0.9	-0.1	0.1	-0.1	0.4	-1.1	1.1
Total resting periods, locomotor time 2	0.4	0.4	2.7	0.2	-0.4	0.4	0.0	-0.1	0.1	0.6	-0.2	0.2	-1.7	1.7	-0.6	-0.2	0.2	-0.4	-0.5	0.5	0.7	0.1	0.2	-0.2
Distance moved, locomotor task time 2	0.4	0.4	1.1	0.8	-0.9	0.9	0.5	0.1	-0.1	0.3	-0.6	0.6	0.6	-0.6	-0.1	-0.7	0.7	1.0	-0.6	0.6	-0.1	0.9	-0.9	0.9
Vertical activity count, locomotor time 2	0.4	0.4	1.2	0.9	-0.6	0.6	0.3	-0.2	0.2	0.4	-0.7	0.7	0.2	-0.2	0.2	-0.9	0.9	1.1	-0.6	0.6	0.2	0.6	-1.0	1.0
Cd content in liver	0.4	0.5	3.7	0.5	-0.0	0.1	0.4	-0.2	0.2	-0.3	0.1	-0.1	1.9	-1.9	0.2	-0.0	0.0	0.7	-0.2	0.2	-0.9	0.5	-0.1	0.1
Rb content in liver	0.4	0.5	1.5	-0.5	1.1	-1.1	-0.2	-0.1	0.1	-0.6	0.7	-0.7	1.2	-1.2	0.9	0.3	-0.3	-0.1	0.5	-0.5	-0.4	-0.6	0.8	-0.8
Number of licking bursts	0.3	0.3	0.9	-0.5	0.5	-0.5	-0.8	0.5	-0.5	-0.3	0.5	-0.5	-0.6	0.5	0.9	0.6	-0.6	-0.9	0.5	-0.5	0.4	-0.5	0.6	-0.7
Mean num. licks in bursts	0.3	0.4	5.0	0.2	0.1	-0.1	0.3	0.2	-0.2	-0.2	-0.0	0.0	0.7	-0.7	-2.2	-0.0	0.0	0.4	-0.2	0.2	-1.2	0.0	0.0	-0.0
Indifference point function ln k	0.3	0.4	1.1	-0.2	0.6	-0.6	-1.1	0.8	-0.8	-0.5	0.4	-0.4	-0.6	0.6	0.6	0.5	-0.5	-0.8	0.5	-0.5	0.3	-0.7	0.6	-0.6
Indifference point function log k	0.3	0.4	1.1	-0.2	0.6	-0.6	-1.1	0.8	-0.8	-0.5	0.4	-0.4	-0.6	0.6	0.6	0.5	-0.5	-0.8	0.5	-0.5	0.3	-0.7	0.6	-0.6
Reaction time false alarm rate	0.3	0.4	1.8	-0.9	-0.2	0.1	-0.2	0.5	-0.5	-0.0	0.6	-0.6	-1.3	1.3	0.5	0.4	-0.4	-1.3	0.3	-0.3	0.7	-0.2	0.5	-0.5
Cocaine response after cond. not corrected	0.3	0.3	2.0	-0.6	-0.5	0.5	0.6	-0.6	0.6	0.6	-0.0	0.0	-0.0	0.0	1.4	-0.3	0.3	0.3	0.1	-0.1	0.7	0.3	-0.8	0.8
Condit. Reinf. active responses	0.3	0.4	1.3	0.5	-0.4	0.3	0.4	-0.5	0.5	0.6	-0.8	0.8	-1.1	1.1	-0.5	-0.6	0.6	0.3	-0.7	0.7	0.7	0.2	-0.4	0.4
Conditioned reinforcement - actives	0.3	0.3	0.4	-0.0	-0.6	0.6	0.5	-0.4	0.4	0.1	-0.6	0.6	-0.4	0.4	0.5	-0.6	0.6	0.6	-0.6	0.6	0.6	0.5	-0.5	0.6
Conditioned reinforcement - inactives	0.3	0.4	0.7	0.8	-0.8	0.8	0.5	0.0	-0.0	0.1	-0.7	0.7	-0.6	0.6	-0.7	-0.7	0.7	0.5	-0.6	0.6	0.3	0.8	-0.7	0.7
Short access total infusions	0.3	0.4	1.2	0.1	-0.1	0.1	-0.7	1.0	-1.0	-0.8	-0.5	0.5	-1.1	1.1	0.4	-0.4	0.4	-0.1	-0.5	0.5	0.7	0.3	-0.0	0.1
Degree of sensitization stereotypy	0.3	0.3	2.0	-0.2	-0.4	0.5	0.0	0.6	-0.6	-0.2	0.3	-0.3	-1.1	1.1	-1.4	0.2	-0.2	-0.7	0.3	-0.3	0.0	0.0	0.3	-0.3
Locomotion velocity, hab. session 1	0.3	0.4	1.0	-1.0	0.7	-0.7	-0.4	0.4	-0.4	-0.5	0.8	-0.8	0.6	-0.6	0.1	0.7	-0.7	-0.7	0.7	-0.7	-0.6	-0.7	0.5	-0.5
Time in familiar zone, hab. session 2	0.3	0.3	1.8	-1.3	0.2	-0.2	0.6	-0.3	0.3	0.3	0.2	-0.2	0.5	-0.5	-0.9	0.4	-0.4	-0.0	0.3	-0.3	-0.8	-0.3	-0.5	0.5
Bone: elastic displacement	0.3	0.4	2.6	1.0	-0.0	0.0	-0.5	1.0	-1.0	-0.6	0.1	-0.1	-0.3	0.3	-1.6	0.2	-0.2	-0.3	0.2	-0.2	-0.5	-0.1	0.6	-0.5
Time in closed arm after self-admin	0.3	0.3	0.5	0.3	-0.7	0.7	0.7	-0.6	0.6	0.1	-0.6	0.6	-0.0	0.0	0.2	-0.5	0.5	0.5	-0.6	0.6	0.3	0.7	-0.4	0.4
Area under the delay curve	0.3	0.3	1.1	0.6	-0.9	0.9	-0.1	0.5	-0.5	0.1	-0.3	0.3	-1.0	1.0	-0.4	-0.3	0.3	0.0	-0.1	0.1	0.6	0.4	-0.4	0.4
Distance moved, locomotor task time 1	0.3	0.3	1.0	0.3	-0.8	0.8	0.7	-0.4	0.4	0.6	-0.4	0.4	0.2	-0.2	0.0	-0.5	0.5	0.6	-0.3	0.3	0.1	0.6	-1.0	1.0
Bouts of movement, locomotor time 2	0.3	0.3	1.6	0.1	-0.6	0.6	0.3	-0.2	0.2	0.6	-0.3	0.3	-1.3	1.3	-0.7	-0.3	0.3	-0.2	-0.5	0.5	0.5	0.2	-0.1	0.1
Latency to leave start box in cocaine runway	0.3	0.4	2.2	-1.5	0.0	-0.0	0.2	0.3	-0.3	-0.6	0.6	-0.6	0.2	-0.2	1.1	0.6	-0.6	-0.7	0.7	-0.7	0.1	-0.3	0.7	-0.7
Delay discounting water rate 0 sec	0.2	0.2	1.2	1.1	-0.7	0.7	-0.1	0.0	-0.0	0.3	-0.4	0.4	-0.6	0.6	0.3	-0.6	0.6	0.4	-0.2	0.2	0.6	0.6	-0.2	0.2
Delay discounting water rate 24 sec	0.2	0.2	0.7	-0.5	-0.6	0.6	0.8	-0.6	0.6	0.4	0.0	-0.0	0.2	-0.2	-0.1	-0.0	0.0	0.3	0.3	-0.3	-0.1	0.4	-0.9	0.9
Reaction time num false alarms AUC	0.2	0.3	1.6	-0.2	-0.7	0.7	0.4	-0.2	0.2	0.8	0.0	-0.0	-1.2	1.3	0.1	-0.2	0.2	-0.5	-0.2	0.2	0.7	0.2	-0.2	0.2
Condit. Reinf. lever reinforcers received	0.2	0.3	1.6	0.3	-0.2	0.2	0.2	-0.3	0.3	0.5	-0.6	0.6	-1.3	1.3	-0.6	-0.4	0.4	0.1	-0.6	0.6	0.6	-0.0	-0.2	0.2
Pavlov. Cond. lever latency	0.2	0.2	0.8	0.0	-0.5	0.5	0.7	-0.8	0.8	0.5	-0.2	0.2	0.3	-0.3	0.9	-0.3	0.3	0.4	-0.2	0.2	0.4	0.3	-0.3	0.3
Pavlov. Cond. lever contacts	0.2	0.2	2.3	-0.1	0.4	-0.4	-0.3	0.6	-0.6	-0.4	0.2	-0.2	0.1	-0.1	-1.5	0.3	-0.3	-0.2	0.2	-0.2	-0.8	-0.2	0.1	-0.1
Intermittent access intake day 1-15 change	0.2	0.2	2.8	0.2	-0.2	0.3	0.5	-0.2	0.1	0.5	0.2	-0.2	-0.0	0.1	-1.7	0.1	-0.1	-0.2	0.2	-0.2	-0.6	-0.1	0.2	-0.2
Intermittent access intake escalation	0.2	0.2	0.9	-0.1	-0.0	0.0	0.4	-0.2	0.2	0.4	0.5	-0.5	0.2	-0.2	-1.0	0.3	-0.3	-0.4	0.5	-0.5	-0.5	-0.4	0.4	-0.4
Progressive ratio test 1 active lever presses	0.2	0.2	0.8	-0.1	0.4	-0.4	-0.9	0.9	-0.9	-0.8	0.0	-0.0	-0.3	0.3	0.2	0.1	-0.1	-0.3	0.0	-0.0	0.1	-0.3	0.5	-0.5
Short access day 10 total inactive lever presses	0.2	0.2	1.2	-0.5	-0.1	0.1	0.7	-1.1	1.1	0.8	0.3	-0.3	0.3	-0.2	0.5	0.4	-0.4	-0.2	0.3	-0.3	0.1	-0.2	0.0	-0.0
Degree of sensitization distance	0.2	0.2	1.7	-0.4	0.4	-0.4	-0.6	0.0	-0.0	-0.0	0.3	-0.3	-0.2	0.2	1.3	0.2	-0.2	-0.4	0.3	-0.3	0.3	-0.5	0.0	-0.0
Novel to familiar place preference ratio	0.2	0.3	0.6	0.8	0.2	-0.2	-0.7	0.7	-0.7	-0.4	0.6	-0.6	-0.1	0.1	-0.4	0.3	-0.3	-0.5	0.6	-0.6	-0.4	-0.3	0.7	-0.7
Novelty place preference	0.2	0.2	1.0	1.0	-0.0	0.0	-0.6	0.6	-0.6	-0.2	0.4	-0.4	-0.5	0.5	-0.4	0.0	-0.0	-0.5	0.4	-0.4	-0.1	-0.1	0.6	-0.5
Time in novel zone, NPP test	0.2	0.2	1.3	1.1	-0.2	0.2	-0.4	0.4	-0.4	-0.0	0.1	-0.1	-0.8	0.8	-0.5	-0.2	0.2	-0.3	0.1	-0.1	0.1	0.1	0.4	-0.4
Bone: elastic work	0.2	0.3	1.2	1.1	-0.9	0.9	0.4	0.1	-0.1	0.1	-0.3	0.3	-0.4	0.4	-0.5	-0.3	0.3	0.4	-0.3	0.3	0.3	0.9	-0.3	0.3
Bone: maximum diameter	0.2	0.5	3.5	-0.8	-0.4	0.4	0.2	-0.3	0.3	0.2	-0.2	0.2	-1.1	1.1	1.9	0.0	-0.0	-0.3	-0.1	0.1	1.4	0.4	-0.0	0.0
Extinction: sum of active levers before priming	0.2	0.3	0.6	-0.1	0.7	-0.7	-0.8	0.5	-0.5	-0.6	0.5	-0.5	-0.2	0.1	0.5	0.4	-0.4	-0.6	0.6	-0.6	0.0	-0.6	0.4	-0.4
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.9	0.8	0.3	-0.3	-1.0	0.6	-0.6	-0.3	0.0	-0.0	-0.9	0.8	0.0	-0.2	0.2	-0.3	0.0	-0.0	0.5	-0.2	0.5	-0.5
Ambulatory time before self-admin	0.2	0.2	1.0	-0.3	0.2	-0.2	0.3	-0.3	0.3	-0.1	0.5	-0.5	1.0	-1.0	0.2	0.4	-0.4	0.0	0.4	-0.4	-0.4	-0.2	0.3	-0.3
Delay disc. indifference point, 16s delay	0.2	0.2	1.3	0.7	-0.4	0.4	-0.1	0.7	-0.7	-0.2	0.0	-0.0	-0.2	0.2	-1.2	0.1	-0.1	-0.0	0.1	-0.1	-0.3	0.1	-0.1	0.1
Delay disc. indifference point, 8s delay	0.2	0.2	1.0	0.1	-0.1	0.1	-0.7	1.0	-1.0	-0.5	0.3	-0.3	-0.4	0.4	-0.4	0.3	-0.3	-0.4	0.5	-0.5	-0.0	-0.3	0.2	-0.2
Rest time, locomotor task time 1	0.2	0.2	1.1	1.0	-0.0	0.0	-0.2	-0.0	-0.0	0.1	-0.4	0.4	-0.9	0.9	0.0	-0.3	0.3	-0.1	-0.3	0.3	0.6	0.4	0.4	-0.4
Rest time, locomotor task time 2	0.2	0.3	2.9	-0.5	0.5	-0.5	-0.1	-0.4	0.4	-0.1	0.4	-0.4	0.2	-0.2	1.7	0.5	-0.5	-0.4	0.5	-0.5	0.4	-0.1	0.4	-0.5
Extensor digitorum longus weight	0.1	0.4	2.1	-0.2	-0.3	0.3	0.4	-0.7	0.7	0.2	-0.5	0.5	-0.5	0.5	1.5	-0.6	0.6	0.4	-0.5	0.5	1.1	0.6	-0.7	0.7
Tibialis anterior weight	0.1	0.2	0.7	-0.7	0.0	-0.0	0.6	-0.2	0.2	-0.1	0.2	-0.2	0.8	-0.8	-0.8	0.2	-0.2	0.1	0.1	-0.1	-0.7	-0.2	-0.1	0.1
Water consumed over 24 hours	0.1	0.1	0.5	0.4	-0.0	0.0	-0.4	0.1	-0.1	-0.1	0.1	-0.1	-0.3	0.3	0.7	0.2	-0.2	-0.3	-0.2	0.2	0.4	0.1	0.3	-0.3
Delay discounting water rate 18 sec	0.1	0.1	0.8	0.9	-0.2	0.2	-0.5	-0.1	0.1	0.2	-0.5	0.5	-0.2	0.2	-0.0	-0.3	0.3	0.4	-0.3	0.3	0.1	0.3	-0.4	0.4
Delay discounting water rate 6 sec	0.1	0.2	0.4	0.5	0.1	-0.1	-0.2	0.4	-0.4	-0.3	0.4	-0.4	0.5	-0.5	-0.5	0.3	-0.3	-0.1	0.6	-0.6	-0.5	-0.3	0.4	-0.4
Reaction time num false alarms	0.1	0.1	0.4	-0.4	-0.3	0.3	0.2	-0.0	0.0	0.3	0.3	-0.3	-0.7	0.7	0.2	0.1	-0.1	-0.5	0.1	-0.1	0.4	0.0	0.1	-0.1
Condit. Reinf. inactive responses	0.1	0.2	0.6	-0.1	0.7	-0.7	-0.2	0.0	-0.0	-0.1	-0.1	0.1	0.4	-0.4	-0.8	0.2	-0.2	0.1	0.0	-0.0	-0.6	-0.8	0.1	-0.1
Condit. Reinf. lever presses	0.1	0.2	0.6	-0.7	0.5	-0.5	-0.4	0.5	-0.5	-0.4	0.1	-0.1	-0.7	0.7	-0.8	0.2	-0.2	-0.4	0.2	-0.2	-0.2	-0.4	-0.0	0.0
Pavlov. Cond. magazine entry latency	0.1	0.1	0.3	-0.4	-0.1	0.1	-0.2	0.5	-0.5	-0.5	0.2	-0.2	-0.4	0.3	0.1	0.3	-0.3	-0.4	0.2	-0.2	0.1	0.3	0.3	-0.2
Pavlov. Cond. change in total contacts	0.1	0.2	1.7	0.3	-0.1	0.1	-0.1	0.4	-0.4	-0.0	-0.2	0.2	-0.9	0.9	-1.3	-0.2	0.2	-0.1	-0.2	0.2	-0.0	0.4	-0.1	0.1
Pavlov. Cond. index score	0.1	0.1	0.4	-0.2	0.2	-0.2	-0.4	0.6	-0.6	-0.4	0.1	-0.1	-0.5	0.5	-0.7	0.2	-0.2	-0.4	0.1	-0.1	-0.2	0.1	0.2	-0.2
Pavlov. Cond. latency score	0.1	0.1	0.3	-0.1	-0.0	0.0	-0.2	0.4	-0.4	-0.2	-0.1	0.1	-0.6	0.6	-0.6	-0.0	0.0	-0.1	-0.1	0.1	0.0	0.3	-0.1	0.1
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	0.3	-0.1	0.0	0.0	-0.3	0.3	0.4	-0.2	0.2	-0.2	0.2	0.2	-0.3	0.3	0.2	-0.3	0.3	0.3	-0.2	-0.3	0.2
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.4	-0.2	0.2	-0.1	-0.3	0.5	-0.5	-0.4	0.0	-0.0	-0.4	0.4	-0.6	0.2	-0.2	-0.3	0.0	-0.0	-0.1	0.1	0.1	-0.1
Conditioned locomotion	0.1	0.1	0.3	0.4	-0.1	0.1	-0.4	0.3	-0.2	-0.4	-0.4	0.4	-0.2	0.2	0.6	-0.4	0.4	0.3	-0.4	0.4	0.5	0.2	0.1	-0.1
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.2	0.1	0.1	-0.1	-0.2	0.5	-0.5	-0.5	-0.1	0.1	-0.3	0.3	-0.4	-0.0	0.0	-0.1	-0.1	0.1	-0.0	-0.1	0.2	-0.2
Intermittent access total infusions	0.1	0.2	0.8	-0.1	0.4	-0.4	-0.5	0.8	-0.8	-0.9	0.1	-0.1	0.0	-0.0	-0.5	0.1	-0.1	-0.2	0.1	-0.1	-0.3	-0.3	0.3	-0.3
Intermittent access total locomotion	0.1	0.1	0.3	0.2	-0.2	0.2	0.2	-0.3	0.3	0.2	-0.4	0.4	0.4	-0.4	0.1	-0.3	0.3	0.6	-0.4	0.4	-0.1	0.5	-0.3	0.3
Post-drug Anxiety	0.1	0.2	1.1	-0.6	0.3	-0.3	0.3	-0.7	0.7	0.2	0.1	-0.1	0.4	-0.4	1.0	0.2	-0.2	0.1	0.0	-0.0	0.2	-0.0	-0.2	0.1
Lifetime Intake	0.1	0.1	0.7	-0.1	0.2	-0.2	-0.5	0.8	-0.8	-0.8	-0.1	0.1	-0.3	0.3	-0.1	-0.1	0.1	-0.1	-0.2	0.2	0.0	-0.1	0.2	-0.2
Progressive ratio test 1 breakpoint	0.1	0.1	0.5	-0.1	0.3	-0.3	-0.7	0.7	-0.7	-0.6	-0.2	0.2	-0.4	0.4	0.4	-0.0	0.0	-0.1	-0.2	0.2	0.2	-0.2	0.3	-0.3
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.2	0.1	0.0	-0.0	0.2	-0.3	0.3	0.2	-0.2	0.2	0.5	-0.5	-0.1	0.0	-0.0	0.3	-0.2	0.2	-0.3	0.1	-0.2	0.2
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.7	-0.0	-0.0	0.0	-0.2	0.6	-0.6	-0.8	-0.0	0.0	-0.5	0.5	-0.1	0.1	-0.1	-0.4	-0.0	0.0	0.2	0.1	0.6	-0.5
Total sessions with >9 infusions	0.1	0.1	0.7	-0.2	0.1	-0.1	-0.5	0.7	-0.7	-0.8	-0.3	0.3	-0.1	0.1	0.6	-0.1	0.1	-0.0	-0.3	0.3	0.2	0.1	0.1	-0.0
Short access day 10 total infusions	0.1	0.1	0.2	-0.1	-0.1	0.1	-0.3	0.4	-0.4	-0.3	-0.3	0.3	-0.4	0.4	0.3	-0.1	0.1	0.0	-0.3	0.3	0.3	0.2	-0.0	0.0
One hour access (shock baseline)	0.1	0.1	0.3	0.1	-0.2	0.2	0.1	0.3	-0.3	-0.5	-0.1	0.1	0.3	-0.3	-0.5	-0.2	0.2	0.3	-0.0	0.0	-0.3	0.2	-0.1	0.1
Locomotion velocity, session 3	0.1	0.1	1.4	0.3	-0.3	0.3	0.4	0.1	-0.1	0.2	-0.3	0.3	-0.4	0.4	-1.2	-0.2	0.2	0.1	-0.3	0.3	-0.1	0.2	-0.1	0.1
Condit. Reinf. active-inactive response ratio	0.1	0.2	1.5	-0.0	-0.2	0.2	-0.2	0.5	-0.5	-0.0	-0.3	0.3	-0.6	0.6	-1.2	0.0	-0.0	0.0	-0.2	0.2	-0.1	0.1	-0.3	0.3
Bone volume	0.1	0.2	0.9	-0.4	0.4	-0.3	0.2	-0.3	0.3	0.1	0.4	-0.4	1.0	-0.9	-0.3	0.3	-0.3	0.0	0.4	-0.4	-0.6	-0.2	0.0	-0.0
Delta time in open arm before/after self-admin	0.1	0.1	1.8	-0.1	0.3	-0.3	-0.1	0.5	-0.5	-0.3	0.0	-0.0	-0.0	0.0	-1.3	0.2	-0.2	-0.1	0.0	-0.0	-0.5	-0.2	0.1	-0.1
Active lever presses in extinction session 6	0.1	0.1	0.8	0.9	0.2	-0.2	-0.4	0.6	-0.6	-0.8	-0.1	0.1	0.4	-0.4	-0.1	-0.2	0.2	0.4	-0.1	0.1	-0.2	0.0	0.1	-0.0
Time in closed arm before self-admin	0.1	0.1	0.2	0.3	-0.2	0.2	0.0	-0.0	0.0	0.0	-0.4	0.4	-0.4	0.4	0.1	-0.3	0.3	0.1	-0.3	0.3	0.3	0.2	-0.2	0.2
Total heroin consumption	0.1	0.1	0.7	0.9	0.3	-0.3	-0.3	0.1	-0.1	-0.1	0.1	-0.1	0.0	-0.0	-0.3	0.1	-0.1	-0.1	0.1	-0.1	-0.1	-0.3	0.4	-0.4
Delay disc. indifference point, 0s delay	0.1	0.1	1.1	-0.3	-0.2	0.2	-0.3	0.4	-0.4	-0.3	0.1	-0.1	-0.3	0.3	1.0	0.0	-0.0	-0.3	0.1	-0.1	0.5	-0.0	-0.1	0.1
Fecal boli incidents, locomotor time 1	0.1	0.1	0.4	0.2	0.6	-0.6	-0.4	0.2	-0.2	-0.7	-0.1	0.1	0.4	-0.4	0.2	-0.0	0.0	0.2	0.1	-0.1	-0.2	-0.3	0.1	-0.1
Locomotion in novel chamber	0.1	0.1	0.4	0.7	-0.5	0.5	0.6	-0.3	0.3	0.3	-0.3	0.3	-0.3	0.3	-0.3	-0.3	0.3	0.2	-0.4	0.4	0.2	0.5	-0.3	0.3
Run reversals in cocaine runway, females	0.1	0.1	0.5	0.6	0.2	-0.1	-0.2	0.1	-0.1	-0.3	-0.1	0.1	0.7	-0.7	-0.7	-0.0	0.0	0.4	0.1	-0.1	-0.7	-0.1	-0.1	0.1
Run reversals in cocaine runway, males	0.1	0.1	0.3	-0.5	-0.1	0.1	-0.0	0.2	-0.2	-0.1	0.4	-0.4	-0.3	0.2	0.4	0.4	-0.4	-0.6	0.4	-0.4	0.2	0.1	0.5	-0.5
Latency to leave start box in cocaine runway, M	0.1	0.1	0.9	-0.2	-0.7	0.7	1.0	-0.4	0.4	0.2	-0.1	0.1	0.1	-0.1	0.3	-0.0	0.0	0.1	-0.1	0.1	0.2	0.5	-0.2	0.2
Zn content in liver	0.1	0.1	1.3	0.2	-0.1	0.1	-0.1	-0.1	0.1	-0.4	-0.1	0.1	0.1	-0.1	1.2	-0.0	0.0	0.2	-0.1	0.1	0.5	0.2	0.1	-0.1
Intermittent access day 1 locomotion	0.0	0.0	0.2	0.0	0.4	-0.4	-0.4	0.0	-0.0	-0.1	-0.3	0.3	0.1	-0.1	0.3	-0.2	0.2	0.2	-0.2	0.2	0.0	-0.0	-0.0	0.0
Bone surface	0.0	0.1	0.4	-0.5	0.1	-0.0	0.4	-0.7	0.6	0.5	0.1	-0.1	0.2	-0.2	0.3	-0.1	0.1	0.1	0.1	-0.1	0.1	-0.1	-0.3	0.2
Food seeking constrained by brief footshock	0.0	0.1	0.2	0.5	-0.1	0.1	-0.1	0.0	-0.0	0.1	-0.1	0.1	-0.3	0.3	-0.5	-0.2	0.2	0.2	-0.1	0.1	-0.0	0.2	-0.3	0.3

For each tested trait, stats based on TWAS chi² (squared Z-score) for the above models are shown. Avg chi² ratio is the mean chi² across all models for this gene, divided by the mean chi² across all models for all genes. Avg chi² is the mean chi² across all models for this gene. Max chi² is the highest chi² across all models for this gene.

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.