Hub : Genes

RGD1359508

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000058366 0.76 0.03 0.0e+00 0.16 0.13 0.18 0.18 8.1e-18 1.1e-14 3.2e-19 8.3e-20
2 Adipose alternative polyA ENSRNOT00000114451 0.76 0.03 0.0e+00 0.16 0.14 0.18 0.18 6.2e-18 4.3e-15 1.6e-19 4.4e-20
3 Adipose gene expression ENSRNOG00000038330 0.07 0.04 1.2e-12 0.11 0.09 0.09 0.1 3.7e-12 1.3e-10 7.0e-10 4.8e-11
4 BLA gene expression ENSRNOG00000038330 0.12 0.08 6.8e-05 0.04 0.06 0.02 0.05 2.0e-03 5.3e-04 1.9e-02 8.5e-04
5 BLA mRNA stability ENSRNOG00000038330 0.09 0.08 8.6e-03 -0 -0 -0 -0 9.6e-01 8.0e-01 8.1e-01 7.3e-01
6 Brain alternative polyA ENSRNOT00000058366 0.4 0.19 5.7e-03 0.05 0.02 0.02 0.04 4.4e-05 5.8e-03 1.1e-02 2.5e-04
7 Brain alternative polyA ENSRNOT00000114451 0.42 0.2 4.1e-03 0.05 0.02 0.02 0.04 3.7e-05 6.0e-03 4.0e-03 2.3e-04
8 Brain gene expression ENSRNOG00000038330 0.13 0.07 1.2e-14 0.15 0.16 0.12 0.16 1.9e-13 1.5e-14 1.2e-11 2.2e-14
9 Brain intron excision ratio chr2:124783582:124783672 0.03 0.03 7.2e-03 0.02 0.02 0.01 0.02 9.6e-03 5.8e-03 3.5e-02 9.2e-03
10 Brain mRNA stability ENSRNOG00000038330 0.11 0.07 3.8e-11 0.11 0.12 0.12 0.11 2.9e-10 7.5e-11 3.5e-11 1.6e-10
11 LHb gene expression ENSRNOG00000038330 0.28 0.18 1.8e-03 0.07 0.06 0.03 0.08 8.9e-03 1.3e-02 5.9e-02 6.9e-03
12 Liver alternative polyA ENSRNOT00000058366 0.78 0.04 6.0e-11 0.05 0.06 0.07 0.07 2.4e-06 1.7e-07 1.5e-08 1.1e-08
13 Liver alternative polyA ENSRNOT00000114451 0.79 0.03 3.8e-11 0.05 0.06 0.07 0.07 3.4e-06 1.9e-07 1.9e-08 2.7e-08
14 Liver gene expression ENSRNOG00000038330 0.07 0.04 2.6e-12 0.06 0.08 0.06 0.06 2.1e-07 7.3e-09 2.2e-07 1.1e-07
15 NAcc gene expression ENSRNOG00000038330 0.23 0.12 1.0e-13 0.14 0.14 0.14 0.14 7.1e-11 8.5e-11 5.9e-11 1.1e-10
16 PL gene expression ENSRNOG00000038330 0.13 0.07 1.9e-11 0.11 0.11 0.11 0.12 5.8e-09 6.0e-09 6.2e-09 3.1e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
BMI with tail4.915.822.4-4.54.54.03.3-3.5-4.14.13.23.3-4.73.9-4.34.53.63.73.9
BMI without tail1.73.68.7-2.82.81.30.5-0.8-2.92.90.40.4-1.91.1-2.62.70.80.71.3
Body weight4.619.526.4-4.94.94.44.0-4.2-4.14.14.04.1-5.14.2-4.75.04.04.34.3
Epididymis fat weight1.84.35.8-2.42.42.01.8-1.9-2.02.01.71.7-2.42.0-2.32.41.81.92.1
Glucose1.01.53.50.1-0.11.71.3-1.5-0.10.11.21.3-1.71.90.2-0.11.71.51.7
Heart weight0.50.81.9-0.30.41.01.3-1.30.3-0.31.41.0-0.61.1-0.40.40.71.11.1
Left kidney weight0.30.81.8-0.60.51.30.7-1.0-0.80.80.60.7-1.31.3-0.40.41.10.91.3
Right kidney weight1.13.16.7-1.01.02.31.8-2.1-1.01.01.71.7-2.32.6-0.80.92.12.02.3
Tail length0.10.20.6-0.70.8-0.1-0.20.1-0.70.7-0.2-0.40.10.0-0.80.8-0.4-0.3-0.1
Length with tail0.51.93.3-1.61.71.11.6-1.5-0.80.81.71.5-1.11.1-1.81.80.91.51.1
Length without tail1.43.15.3-1.91.91.32.1-1.8-0.90.92.32.2-1.41.3-2.02.11.42.01.3
Liver weight, left0.50.82.5-0.50.50.90.9-0.8-0.60.60.71.2-1.60.8-0.40.61.30.81.1
Liver weight, right0.30.61.1-0.60.6-0.6-1.01.0-1.01.0-1.1-0.80.1-0.6-0.50.5-0.5-0.8-0.7
Parametrial fat weight0.61.12.1-0.90.81.21.0-1.1-0.90.91.01.1-1.51.1-0.80.91.21.21.2
Retroperitoneal fat weight1.65.49.4-2.12.02.72.2-2.5-1.91.92.22.3-3.12.5-1.92.12.52.52.6
Intraocular pressure3.54.98.01.9-2.02.52.1-2.11.6-1.61.92.3-2.32.82.3-2.02.82.32.5
Extensor digitorum longus weight2.49.716.9-4.14.02.62.4-2.5-3.43.42.52.4-3.22.6-3.94.12.22.62.6
Soleus weight1.13.38.9-2.92.9-0.1-0.50.3-3.03.0-0.5-0.5-0.50.1-2.92.9-0.4-0.4-0.0
Tibialis anterior weight3.411.926.3-5.15.12.11.7-1.8-4.74.71.71.8-3.22.1-4.95.11.82.02.1
Tibia length0.00.10.3-0.50.50.20.00.1-0.60.6-0.00.2-0.50.1-0.40.50.30.10.2
Number of licking bursts3.13.76.8-2.12.11.91.5-1.6-2.12.11.41.7-2.61.9-1.92.12.01.81.9
Food consumed during 24 hour testing period1.61.93.4-0.10.11.81.7-1.7-0.00.01.61.7-1.81.8-0.00.21.81.81.8
Times rat made contact with spout0.20.31.0-0.10.10.70.4-0.4-0.40.40.30.5-1.00.70.00.10.80.60.8
Mean time between licks in bursts0.91.33.6-0.30.31.31.2-1.1-0.40.41.01.5-1.91.4-0.10.31.71.31.4
Mean num. licks in bursts1.82.23.91.7-1.7-1.4-1.21.31.6-1.6-1.1-1.42.0-1.41.6-1.7-1.5-1.3-1.3
Std. dev. time between licks in bursts0.81.02.0-0.30.31.11.2-1.1-0.10.11.21.4-1.31.2-0.30.41.31.21.1
Water consumed over 24 hours2.53.05.9-0.80.82.21.8-2.0-0.80.81.71.9-2.42.3-0.60.82.22.12.3
Indifference point 0 sec2.03.37.6-2.72.70.80.8-0.8-2.52.50.71.0-1.71.1-2.62.80.90.81.0
Indifference point AUC1.31.52.3-1.41.4-1.1-1.11.0-1.31.3-0.9-1.21.0-1.1-1.51.4-1.3-1.1-1.0
Indifference point function ln k1.52.13.60.9-0.91.71.7-1.61.0-1.01.61.8-1.61.81.0-0.91.91.71.7
Indifference point function log k1.52.13.60.9-0.91.71.7-1.61.0-1.01.61.8-1.61.81.0-0.91.91.71.7
Delay discounting total patch changes 0 sec1.83.07.2-2.72.60.70.6-0.7-2.42.40.60.8-1.51.1-2.62.70.80.70.9
Delay discounting total patch changes 12 sec1.52.03.2-1.61.6-1.3-1.41.3-1.81.8-1.3-1.40.7-1.2-1.71.6-1.3-1.4-1.1
Delay discounting total patch changes 18 sec1.62.26.1-2.42.4-0.1-0.10.1-2.32.3-0.0-0.1-0.5-0.0-2.52.5-0.2-0.10.0
Delay discounting total patch changes 24 sec2.12.77.2-2.72.70.2-0.0-0.1-2.62.60.0-0.1-0.70.3-2.62.6-0.00.20.3
Delay discounting total patch changes 6 sec2.33.67.8-2.82.8-1.0-1.11.2-2.82.8-1.1-1.10.3-0.9-2.82.8-1.2-1.1-0.9
Delay discounting time to switch 0 sec0.60.92.61.5-1.50.40.3-0.21.2-1.20.20.5-0.50.11.6-1.50.70.40.4
Delay discounting water rate 0 sec0.40.71.0-0.90.9-0.6-0.80.6-0.90.9-0.7-1.00.8-0.5-1.00.9-1.0-0.7-0.7
Delay discounting water rate 12 sec0.60.92.1-1.41.4-0.5-0.60.6-1.41.4-0.6-0.60.1-0.7-1.41.4-0.5-0.6-0.4
Delay discounting water rate 18 sec0.40.51.5-1.21.10.3-0.00.1-1.21.2-0.10.0-0.6-0.0-1.11.10.20.10.0
Delay discounting water rate 24 sec1.31.85.5-1.91.9-0.2-0.90.7-2.32.3-0.9-0.8-0.4-0.3-1.81.8-0.3-0.6-0.2
Delay discounting water rate 6 sec0.20.30.9-0.80.80.4-0.10.0-0.90.9-0.2-0.0-0.60.2-0.60.70.30.10.4
Locomotor activity0.40.71.60.5-0.40.51.2-1.01.1-1.11.31.2-0.30.60.3-0.30.60.90.4
Locomotor testing distance0.81.32.3-1.21.20.81.4-1.3-0.40.41.51.5-0.90.9-1.31.40.81.20.8
Locomotor testing rearing0.20.30.9-0.80.8-0.5-0.30.2-0.50.5-0.2-0.30.4-0.3-0.90.9-0.6-0.4-0.4
Light reinforcement 10.20.41.30.9-0.9-0.20.2-0.21.1-1.10.20.20.5-0.20.8-0.8-0.2-0.1-0.1
Light reinforcement 20.70.92.71.5-1.5-0.10.3-0.21.6-1.60.30.20.6-0.11.4-1.4-0.00.00.0
Reaction time number correct2.43.56.7-0.30.3-2.1-2.52.5-0.80.8-2.6-2.51.8-2.2-0.20.1-2.1-2.5-2.2
Reaction time mean minus median7.39.516.9-0.20.23.84.1-4.10.7-0.74.14.1-3.43.8-0.20.43.74.13.7
Reaction time mean minus median AUC5.77.312.6-0.70.73.43.4-3.5-0.10.13.33.5-3.43.3-0.60.83.43.63.3
Reaction time num false alarms0.50.61.10.8-0.80.80.8-0.90.9-0.90.90.7-0.51.10.7-0.70.70.90.7
Reaction time num false alarms AUC0.30.40.91.0-1.00.50.2-0.30.8-0.80.20.1-0.10.70.9-1.00.30.30.3
Reaction time trials correct on left2.43.56.7-0.30.3-2.1-2.52.5-0.80.8-2.6-2.51.8-2.2-0.20.1-2.1-2.5-2.2
Reaction time trials on left2.12.95.7-0.20.2-2.0-2.32.3-0.70.7-2.4-2.31.7-2.1-0.20.1-2.0-2.3-2.0
Reaction time mean6.69.016.3-0.20.23.74.0-4.00.7-0.74.03.9-3.33.6-0.20.43.64.03.6
Reaction time mean AUC7.19.517.4-0.10.13.94.1-4.10.8-0.84.24.0-3.23.8-0.20.33.64.13.7
Median of all reaction times4.46.010.8-0.00.03.13.2-3.20.7-0.73.33.2-2.62.9-0.00.22.93.33.0
Reaction time omissions12.416.730.51.1-1.14.85.4-5.52.2-2.25.45.2-3.85.01.1-0.94.75.44.9
Reaction time false alarm rate0.91.32.30.7-0.71.31.4-1.40.9-0.91.41.2-0.91.50.7-0.61.21.41.2
Reaction time premature initiation rate4.25.69.92.7-2.7-2.3-1.81.82.6-2.6-1.6-2.13.1-2.32.5-2.7-2.4-2.0-2.2
Reaction time premature initiations5.27.412.82.2-2.2-3.0-2.92.81.8-1.8-2.7-3.13.6-3.12.0-2.3-3.1-3.0-3.0
Std. dev. reaction times9.112.522.0-0.70.74.34.6-4.60.4-0.44.64.7-4.14.4-0.60.94.24.74.2
Reaction time trials completed2.12.95.7-0.20.2-2.0-2.32.3-0.70.7-2.4-2.31.7-2.1-0.20.1-2.0-2.3-2.0
Reaction time trials AUC2.13.05.7-0.20.2-2.0-2.42.3-0.70.7-2.4-2.41.7-2.1-0.20.1-2.0-2.3-2.0
Social response proportion2.62.98.42.7-2.80.80.5-0.52.3-2.30.20.6-0.50.82.9-2.81.10.50.7
Social responses0.30.41.3-0.70.70.1-0.50.4-1.11.1-0.6-0.5-0.30.1-0.70.7-0.0-0.30.0
Social time1.72.25.42.3-2.3-0.9-0.80.71.9-1.9-0.8-0.71.1-0.82.3-2.3-0.5-0.8-0.8
Conditioned locomotion0.70.92.81.6-1.60.2-0.20.01.2-1.2-0.3-0.40.30.21.6-1.70.1-0.10.2
Cocaine response after cond. corrected0.40.41.00.8-0.80.30.6-0.61.0-1.00.60.7-0.30.40.7-0.70.50.50.4
Cocaine response after cond. not corrected0.40.41.20.9-0.9-0.5-0.10.21.1-1.1-0.00.00.6-0.40.8-0.8-0.3-0.3-0.5
Cocaine response before conditioning1.51.93.9-0.20.3-1.8-1.51.6-0.20.2-1.3-1.62.0-1.8-0.40.3-1.9-1.7-1.8
Saline control response0.40.51.3-1.01.0-0.6-0.30.3-0.80.8-0.2-0.40.6-0.8-1.11.1-0.8-0.5-0.5
Condit. Reinf. active minus inactive responses2.83.57.50.00.02.22.6-2.70.7-0.72.72.4-1.52.3-0.10.11.92.42.3
Condit. Reinf. active-inactive response ratio7.27.511.41.9-1.93.03.3-3.42.4-2.43.23.2-2.13.12.0-1.93.03.23.0
Condit. Reinf. active responses0.71.02.3-1.31.40.61.0-1.1-0.70.71.10.9-0.40.6-1.51.50.30.80.8
Condit. Reinf. inactive responses4.25.213.4-3.53.5-1.3-1.11.2-3.13.1-1.0-1.10.6-1.4-3.73.6-1.6-1.2-1.2
Condit. Reinf. lever presses1.21.63.3-1.01.01.21.7-1.7-0.20.21.81.7-1.11.1-1.11.11.11.61.3
Condit. Reinf. lever reinforcers received0.60.92.3-1.41.40.50.9-1.0-0.70.71.10.8-0.30.4-1.51.50.20.70.6
Pavlov. Cond. lever latency1.62.26.22.4-2.4-0.5-0.80.81.8-1.8-1.0-0.80.7-0.42.5-2.5-0.3-0.8-0.5
Pavlov. Cond. magazine entry latency1.61.84.3-2.02.00.81.0-1.0-1.61.61.00.9-1.00.8-2.02.10.70.90.8
Pavlov. Cond. change in total contacts2.33.18.0-2.62.70.91.6-1.6-1.51.51.91.5-0.80.7-2.82.80.51.41.0
Pavlov. Cond. index score3.34.410.5-3.13.11.21.5-1.5-2.42.41.61.4-1.51.1-3.23.20.91.51.2
Pavlov. Cond. latency score3.24.08.8-2.92.91.31.6-1.6-2.12.11.71.6-1.61.2-2.93.01.11.61.3
Pavlov. Cond. lever contacts2.02.88.3-2.82.80.30.5-0.6-2.22.20.70.4-0.60.2-2.92.9-0.00.50.3
Pavlov. Cond. magazine entry number3.84.611.23.2-3.2-1.3-1.51.62.4-2.4-1.7-1.41.5-1.23.3-3.3-0.9-1.5-1.3
Pavlov. Cond. intertrial magazine entries0.10.10.40.6-0.60.1-0.30.10.2-0.2-0.4-0.3-0.00.40.7-0.60.1-0.10.0
Pavlov. Cond. lever-magazine prob. diff.3.14.09.8-3.03.01.21.4-1.4-2.32.31.51.4-1.41.0-3.13.10.91.41.1
Pavlov. Cond. response bias2.33.29.8-3.03.00.40.8-0.9-2.22.21.00.6-0.50.3-3.13.1-0.00.70.4
Conditioned reinforcement - actives2.32.33.71.3-1.3-1.6-1.81.70.8-0.8-1.9-1.81.4-1.71.3-1.4-1.4-1.8-1.5
Conditioned reinforcement - inactives4.65.210.01.7-1.7-2.8-2.12.21.9-1.9-2.0-2.23.2-2.91.5-1.7-2.7-2.4-2.8
Conditioned locomotion0.40.50.9-0.30.3-0.9-0.90.9-0.50.5-0.9-0.80.6-0.9-0.30.3-0.7-0.7-0.8
Intermittent access intake day 1-15 change2.32.26.22.4-2.4-0.5-0.20.12.3-2.3-0.2-0.20.7-0.32.5-2.5-0.1-0.3-0.2
Intermittent access intake escalation2.42.46.52.5-2.50.10.4-0.52.4-2.40.30.40.20.32.6-2.50.50.30.4
Intermittent access intake escalation 20.20.20.50.6-0.6-0.00.3-0.50.6-0.60.30.4-0.20.30.7-0.60.50.40.5
Intermitt. access day 1 inactive lever presses0.60.61.5-0.60.6-0.8-0.70.5-0.30.3-0.6-1.01.1-0.9-0.80.6-1.2-0.9-0.9
Intermitt. access day 15 inactive lever presses1.71.83.41.6-1.5-1.4-0.70.91.8-1.8-0.6-0.91.8-1.31.4-1.5-1.2-0.8-1.5
Intermitt. access escalation Index1.31.21.81.2-1.2-1.0-0.91.01.2-1.2-0.8-0.91.3-1.21.1-1.2-1.1-1.0-1.0
Intermittent access day 1 total infusions2.02.33.81.4-1.4-1.8-1.41.81.3-1.3-1.5-1.11.6-1.71.4-1.5-1.3-1.5-1.9
Intermittent access day 15 total infusions2.12.45.82.4-2.4-0.9-0.30.52.4-2.4-0.4-0.21.0-0.62.4-2.4-0.2-0.4-0.8
Intermittent access terminal intake (last 3 days)1.21.32.81.6-1.6-1.1-0.60.81.6-1.6-0.7-0.40.9-0.81.7-1.7-0.4-0.6-0.9
Intermittent access total infusions1.31.42.21.2-1.2-1.5-1.01.31.1-1.1-1.1-0.81.2-1.31.2-1.2-0.9-1.1-1.5
Intermittent access day 1 locomotion0.60.61.3-0.40.4-1.0-0.91.1-0.40.4-1.0-0.80.6-1.0-0.40.3-0.8-0.9-1.1
Intermittent access day 15 total locomotion0.10.10.4-0.40.4-0.6-0.20.3-0.20.2-0.2-0.10.2-0.4-0.40.4-0.2-0.2-0.3
Intermittent access total locomotion0.40.40.8-0.90.9-0.5-0.60.6-0.90.9-0.6-0.40.1-0.6-0.80.8-0.4-0.5-0.6
Intermittent access standard deviation0.70.71.31.0-1.10.10.7-0.71.1-1.10.70.9-0.30.61.1-1.00.90.90.5
Cocaine induced anxiety1.51.73.7-0.80.81.51.8-1.8-0.10.11.91.7-1.21.4-1.01.01.11.71.4
Post-drug Anxiety0.50.61.3-1.01.00.70.7-0.7-0.50.50.80.8-0.60.4-1.11.10.40.70.4
Baseline Anxiety0.91.02.00.1-0.1-1.2-1.41.3-0.30.3-1.4-1.41.0-1.20.2-0.2-1.1-1.3-1.2
Lifetime Intake1.51.72.61.4-1.4-1.6-1.11.41.3-1.3-1.1-0.81.3-1.41.4-1.4-0.9-1.1-1.5
Incentive Sensitization - Responses0.00.00.10.2-0.2-0.1-0.0-0.00.2-0.2-0.10.1-0.20.00.2-0.20.30.00.2
Incentive Sensitization - Breakpoint0.10.10.20.3-0.3-0.10.1-0.20.3-0.30.10.3-0.20.10.3-0.30.40.20.3
Progressive ratio test 1 active lever presses0.90.92.20.0-0.0-1.4-1.01.20.2-0.2-0.9-0.91.3-1.2-0.1-0.0-1.2-1.0-1.5
Progressive ratio test 1 breakpoint0.90.92.20.00.0-1.4-1.11.30.2-0.2-1.0-1.01.4-1.3-0.1-0.0-1.3-1.1-1.5
Progressive ratio test 1 inactive lever presses1.41.53.0-0.00.0-1.6-1.41.50.1-0.1-1.3-1.51.7-1.6-0.1-0.0-1.7-1.5-1.7
Progressive ratio test 2 active lever presses0.80.91.51.0-1.0-1.2-0.91.00.9-0.9-0.9-0.60.9-0.91.1-1.1-0.5-0.8-0.9
Progressive ratio test 2 breakpoint0.91.02.30.8-0.8-1.5-1.11.20.6-0.6-1.2-0.91.1-1.20.8-0.9-0.8-1.1-1.2
Progressive ratio test 2 inactive lever presses2.02.43.21.8-1.8-1.6-1.21.51.7-1.7-1.2-1.01.6-1.61.7-1.8-1.2-1.3-1.7
Total sessions with >9 infusions0.60.62.31.1-1.1-0.20.20.11.5-1.50.20.30.4-0.61.0-1.0-0.2-0.1-0.6
Short access day 1 total inactive lever presses1.82.03.60.2-0.2-1.9-1.91.9-0.10.1-1.8-1.71.6-1.80.2-0.3-1.5-1.7-1.8
Short access day 10 total inactive lever presses0.30.30.6-0.60.6-0.7-0.50.4-0.50.5-0.4-0.70.8-0.6-0.70.6-0.8-0.4-0.6
Short access day 1 total infusions0.50.51.50.3-0.3-1.1-0.71.00.5-0.5-0.7-0.40.8-1.10.3-0.3-0.7-0.7-1.2
Short access day 10 total infusions0.50.61.20.9-0.9-0.8-0.40.71.1-1.1-0.4-0.20.8-0.80.8-0.8-0.5-0.5-1.0
Short access total infusions1.31.52.71.1-1.1-1.6-1.11.41.0-1.0-1.1-0.81.4-1.51.0-1.1-1.0-1.2-1.6
Short access day 1 locomotion0.60.71.7-1.31.30.2-0.30.3-1.31.3-0.3-0.3-0.4-0.1-1.31.3-0.2-0.2-0.2
Short access day 10 total locomotion2.42.64.6-1.01.02.11.7-1.8-0.90.91.61.7-2.21.9-0.91.01.91.92.0
Short access total locomotion0.10.10.5-0.30.30.60.2-0.2-0.30.30.10.4-0.70.2-0.20.20.50.30.3
Compulsive drug intake2.52.56.3-2.52.50.70.1-0.2-2.52.50.10.2-1.40.7-2.42.40.50.30.7
One hour access (0.3 mA shock)1.41.63.4-0.40.4-1.8-1.61.7-0.60.6-1.7-1.51.2-1.5-0.30.3-1.3-1.5-1.6
One hour access (shock baseline)2.93.34.51.9-1.9-2.1-1.61.81.7-1.7-1.7-1.52.1-1.91.9-2.0-1.5-1.8-2.0
Number of responses in last shaping day0.00.00.1-0.20.20.1-0.10.1-0.30.3-0.1-0.20.0-0.1-0.30.2-0.2-0.1-0.2
Context. condit. distance diff. score0.30.30.80.9-0.90.30.2-0.30.9-0.90.3-0.00.20.60.8-0.90.00.20.3
Locomotion velocity, session 10.70.71.9-1.41.4-0.1-0.20.1-1.31.3-0.2-0.1-0.3-0.5-1.41.4-0.1-0.1-0.1
Locomotion distance, session 11.82.43.7-1.91.91.41.4-1.4-1.51.51.41.4-1.61.2-1.81.91.31.51.3
Locomotion velocity, session 20.70.82.4-0.90.9-0.5-1.01.0-1.61.6-1.2-0.7-0.4-0.8-0.70.8-0.2-0.8-0.5
Locomotion distance, session 21.21.72.5-1.61.61.21.0-1.1-1.51.50.91.1-1.51.1-1.51.61.21.21.2
Locomotion velocity, session 30.20.20.4-0.30.3-0.3-0.60.4-0.50.5-0.6-0.60.2-0.3-0.30.3-0.5-0.6-0.3
Locomotion distance, session 30.50.51.0-0.20.21.00.8-0.9-0.20.20.70.7-1.01.0-0.20.30.90.81.0
Stereotopy head waving bouts, day 31.21.42.9-0.20.2-1.3-1.61.6-0.70.7-1.7-1.71.0-1.4-0.20.1-1.4-1.5-1.3
Stereotopy head waving duration, day 31.41.73.0-0.70.7-1.4-1.71.6-1.01.0-1.6-1.71.1-1.5-0.70.6-1.6-1.6-1.4
Locomotion velocity, session 70.30.31.0-0.80.9-0.30.00.1-0.40.40.2-0.10.5-0.2-1.01.0-0.5-0.1-0.4
Locomotion distance, session 70.50.71.10.9-0.9-0.9-0.60.71.0-1.0-0.6-0.71.0-0.70.8-0.9-0.9-0.8-0.9
Stereotopy head waving bouts, day 71.51.75.9-1.91.80.1-0.70.5-2.42.4-0.8-0.7-0.70.1-1.71.7-0.1-0.40.0
Stereotopy head waving duration, day 71.31.65.4-1.81.8-0.1-0.80.6-2.32.3-0.8-0.7-0.5-0.0-1.71.7-0.3-0.5-0.1
Locomotion velocity, session 81.41.73.6-0.80.81.71.4-1.6-0.70.71.41.3-1.61.9-0.70.81.51.61.6
Locomotion distance, session 80.81.32.5-0.80.81.41.1-1.3-0.80.81.11.0-1.31.6-0.80.81.21.31.3
Degree of sensitization distance1.51.52.11.4-1.3-1.3-0.91.21.3-1.3-0.9-0.91.5-1.21.3-1.4-1.1-1.1-1.3
Degree of sensitization stereotypy1.61.74.3-1.71.71.10.4-0.6-2.12.10.30.4-1.51.1-1.61.60.90.71.0
Condit. Reinf. active minus inactive responses1.11.21.6-1.11.11.11.2-1.2-0.70.71.31.2-1.01.0-1.11.21.01.21.1
Condit. Reinf. active-inactive response ratio0.90.91.7-0.70.71.01.3-1.2-0.20.21.31.2-0.90.8-0.70.81.01.21.1
Condit. Reinf. active responses2.73.35.6-2.22.21.61.8-1.8-1.61.61.81.6-1.61.6-2.32.41.31.81.6
Condit. Reinf. inactive responses2.83.37.9-2.72.81.01.0-1.1-2.42.41.10.8-1.31.3-2.82.80.71.10.9
Incentive salience index mean1.41.72.4-1.11.01.41.5-1.4-0.80.81.51.5-1.51.4-1.01.11.41.51.5
Condit. Reinf. lever presses0.91.22.4-0.80.71.31.1-1.0-0.90.90.91.2-1.51.5-0.60.71.41.21.3
Time in familiar zone, hab. session 10.30.30.6-0.30.3-0.7-0.60.8-0.40.4-0.7-0.50.3-0.5-0.30.3-0.5-0.8-0.7
Time in novel zone, hab. session 10.20.20.6-0.20.2-0.3-0.50.3-0.30.3-0.4-0.80.7-0.5-0.30.2-0.7-0.4-0.4
Total zone transitions, hab. session 10.91.21.9-0.90.91.21.3-1.3-0.60.61.31.3-1.21.3-0.91.01.21.41.1
Total locomotion distance, hab. session 10.30.41.3-1.11.10.10.2-0.2-0.90.90.20.1-0.1-0.0-1.21.1-0.00.20.0
Locomotion velocity, hab. session 10.30.41.0-0.91.00.30.4-0.5-0.70.70.50.4-0.30.2-1.01.00.20.50.3
Time in familiar zone, hab. session 23.63.85.71.5-1.5-2.2-2.22.31.0-1.0-2.3-2.22.1-2.21.5-1.6-2.0-2.4-2.2
Time in novel zone, hab. session 24.64.66.6-1.91.92.52.4-2.6-1.21.22.52.1-2.22.6-1.92.02.02.62.4
Total zone transitions, hab. session 20.70.92.0-1.41.40.60.5-0.6-1.31.30.50.6-0.90.5-1.41.40.60.60.6
Total locomotion distance, hab. session 20.40.60.9-0.90.90.70.7-0.8-0.80.80.70.7-0.80.4-0.90.90.60.70.7
Locomotion velocity, hab. session 20.30.51.1-1.01.00.40.4-0.5-0.90.90.40.4-0.60.1-1.01.00.40.40.4
Novel to familiar place preference ratio0.10.10.2-0.30.30.40.3-0.3-0.20.20.40.1-0.10.4-0.30.30.10.40.3
Novelty place preference0.10.10.2-0.30.30.1-0.0-0.1-0.30.30.1-0.20.20.1-0.40.4-0.20.10.0
Time in novel zone, NPP test0.20.20.7-0.70.80.20.1-0.2-0.60.60.2-0.20.10.2-0.80.8-0.20.10.1
Total zone transitions, NPP test0.10.10.3-0.50.5-0.2-0.10.1-0.40.4-0.1-0.00.1-0.5-0.50.5-0.2-0.1-0.2
Total locomotion distance, NPP test0.00.10.3-0.20.2-0.2-0.10.1-0.10.1-0.1-0.20.3-0.6-0.20.2-0.3-0.1-0.3
Locomotion velocity, NPP test0.10.20.90.1-0.1-0.6-0.50.50.1-0.1-0.5-0.40.5-0.90.1-0.1-0.5-0.5-0.6
Pavlov. Cond. lever latency0.70.92.90.5-0.4-1.1-0.70.70.9-0.9-0.5-1.11.7-1.20.2-0.4-1.5-0.9-1.1
Pavlov. Cond. magazine entry latency1.52.03.2-1.31.31.61.3-1.3-1.31.31.21.3-1.81.6-1.21.31.51.41.5
Pavlov. Cond. change in total contacts0.80.82.3-0.50.41.20.7-0.8-0.90.90.50.8-1.51.1-0.30.41.30.91.2
Pavlov. Cond. index score1.51.94.5-1.31.31.50.9-0.9-1.71.70.61.1-2.11.6-1.01.21.71.21.5
Pavlov. Cond. latency score1.11.43.2-1.21.11.10.6-0.6-1.61.60.40.9-1.81.3-0.91.11.40.81.1
Pavlov. Cond. lever contacts1.11.34.4-0.50.41.40.8-0.8-1.01.00.51.2-2.11.6-0.10.31.81.11.4
Pavlov. Cond. magazine entry number2.43.06.32.2-2.2-1.5-0.80.92.5-2.5-0.6-1.02.2-1.51.9-2.1-1.5-1.1-1.4
Pavlov. Cond. intertrial magazine entries1.82.26.42.3-2.30.20.5-0.52.5-2.50.60.30.60.22.2-2.30.10.40.2
Pavlov. Cond. lever-magazine prob. diff.1.62.04.9-1.21.11.71.0-1.1-1.61.60.81.2-2.21.8-0.91.11.81.31.6
Pavlov. Cond. response bias2.93.68.5-1.51.52.21.5-1.6-1.91.91.21.7-2.92.3-1.21.42.41.82.2
Bone: apparent density0.10.20.40.6-0.6-0.2-0.50.50.2-0.2-0.6-0.60.4-0.20.6-0.6-0.3-0.4-0.2
Bone surface0.20.41.2-1.01.00.20.1-0.3-0.90.90.2-0.10.00.3-1.11.0-0.10.20.1
Bone volume0.00.00.1-0.00.00.1-0.0-0.1-0.10.1-0.0-0.20.10.2-0.10.1-0.10.00.1
Bone: connectivity density0.20.40.8-0.40.4-0.5-0.70.7-0.60.6-0.7-0.90.7-0.5-0.50.4-0.8-0.6-0.5
Bone: cortical apparent density0.71.01.71.0-1.0-0.9-1.21.10.4-0.4-1.3-1.20.8-0.91.1-1.1-0.8-1.2-0.8
Bone: cortical area0.91.32.9-1.71.70.70.6-0.7-1.51.50.70.7-1.00.7-1.71.70.70.70.7
Bone: cortical porosity0.20.31.0-0.40.4-0.6-0.10.10.2-0.20.1-0.31.0-0.4-0.70.6-0.9-0.3-0.5
Bone: cortical porosity0.50.51.7-0.40.5-0.9-0.40.50.1-0.1-0.2-0.71.3-0.8-0.70.6-1.2-0.7-0.9
Bone: cortical thickness0.00.00.10.1-0.10.20.2-0.20.2-0.20.20.2-0.30.30.1-0.10.30.20.1
Bone: cortical thickness0.60.71.6-0.60.61.10.7-0.8-0.70.70.60.8-1.31.0-0.50.51.01.00.9
Bone: cortical tissue density0.70.91.61.0-1.0-0.8-1.21.00.4-0.4-1.3-1.20.8-0.91.1-1.1-0.8-1.1-0.7
Bone: elastic displacement0.80.93.11.5-1.5-0.20.3-0.11.8-1.80.30.20.6-0.11.3-1.4-0.1-0.0-0.1
Bone: elastic work0.91.13.11.7-1.70.00.3-0.01.8-1.80.30.30.30.21.6-1.60.20.10.1
Bone: endosteal estimation2.96.311.2-3.23.22.11.9-2.2-2.82.82.01.8-2.42.2-3.23.31.72.12.1
Bone: endosteal perimeter1.12.35.8-2.32.30.80.8-0.9-2.02.00.90.8-1.00.8-2.42.40.60.90.7
Bone: final force1.11.95.8-2.32.40.10.2-0.1-1.81.80.40.2-0.40.0-2.42.4-0.20.20.1
Bone: final moment1.21.96.1-2.42.40.20.3-0.3-1.81.80.50.2-0.40.1-2.52.4-0.10.30.2
Bone: marrow area3.26.811.8-3.33.32.32.0-2.3-2.92.92.11.9-2.62.4-3.33.41.82.22.2
Bone: maximum diameter1.52.77.3-2.72.70.2-0.0-0.1-2.62.6-0.0-0.0-0.70.3-2.72.70.00.10.1
Bone: maximum force0.81.32.8-1.61.60.80.8-0.8-1.21.20.90.9-1.10.8-1.61.70.70.90.9
Bone: maximum moment0.81.42.9-1.61.60.90.9-0.9-1.21.21.00.9-1.10.8-1.71.70.71.01.0
Bone: minimum diameter1.63.06.7-2.42.41.21.4-1.5-1.81.81.61.4-1.31.3-2.52.61.01.41.1
Bone: periosteal estimation2.24.58.7-2.92.91.71.5-1.7-2.42.41.61.5-2.01.8-2.82.91.41.71.6
Bone: periosteal perimeter1.01.64.8-2.12.1-0.5-0.40.2-1.71.7-0.2-0.50.3-0.5-2.22.1-0.7-0.4-0.5
Bone: post-yield work3.95.310.2-0.20.12.92.7-2.7-0.10.12.52.9-3.23.00.10.23.22.92.9
Bone: stiffness0.91.54.1-2.02.00.2-0.0-0.1-1.91.90.00.1-0.7-0.1-1.92.00.10.10.2
Bone: tissue strength0.70.62.00.5-0.4-1.0-0.30.51.2-1.2-0.0-0.51.4-1.00.2-0.3-1.1-0.6-0.8
Bone: trabecular number0.60.92.20.0-0.0-0.9-1.31.3-0.50.5-1.4-1.50.9-0.80.0-0.1-1.1-1.2-0.9
Bone: trabecular spacing0.20.20.60.3-0.3-0.7-0.30.40.6-0.6-0.3-0.20.6-0.80.3-0.3-0.5-0.5-0.6
Bone: trabecular thickness0.20.20.60.7-0.7-0.1-0.50.40.4-0.4-0.6-0.50.1-0.20.8-0.8-0.1-0.4-0.1
Bone: trabecular tissue density0.20.31.00.9-0.90.1-0.30.10.5-0.5-0.5-0.2-0.20.11.0-1.00.2-0.20.1
Breakpoint value in progressive ratio session0.91.02.40.0-1.01.01.5-1.50.00.01.61.3-0.41.10.00.01.01.51.3
Distance traveled before self-admin0.70.81.70.0-0.70.71.2-1.10.00.01.21.3-0.81.10.00.01.11.11.1
Distance traveled after self-admin0.50.51.30.0-0.80.71.0-0.90.00.00.91.1-0.70.80.00.01.01.00.7
Delta time in closed arm before/after self-admin0.10.10.30.00.4-0.0-0.30.10.00.0-0.2-0.50.4-0.20.00.0-0.5-0.3-0.0
Delta time in open arm before/after self-admin0.00.00.20.0-0.0-0.4-0.20.30.00.0-0.30.1-0.30.00.00.00.3-0.0-0.3
Diff in mean of infusions in LGA sessions1.51.73.40.0-1.61.61.8-1.80.00.01.81.6-0.71.60.00.01.41.81.4
Extinction: sum of active levers before priming0.70.72.20.0-1.40.51.3-1.30.00.01.51.10.20.60.00.00.61.20.9
Active lever presses in extinction session 61.11.12.00.0-0.71.31.4-1.20.00.01.41.4-1.11.10.00.01.31.41.2
Delta distance traveled before/after self-admin0.30.30.60.00.3-0.4-0.80.80.00.0-0.8-0.80.4-0.70.00.0-0.6-0.7-0.8
Delta ambulatory time before/after self-admin0.30.40.70.0-0.0-0.7-0.70.70.00.0-0.7-0.70.8-0.80.00.0-0.8-0.8-0.8
Time in closed arm before self-admin0.91.12.50.00.3-1.0-1.51.60.00.0-1.6-1.30.6-1.30.00.0-1.1-1.4-1.4
Time in closed arm after self-admin1.31.32.80.00.4-0.9-1.61.50.00.0-1.6-1.60.9-1.50.00.0-1.5-1.7-1.3
Time in open arm before self-admin1.51.63.90.0-0.91.41.9-1.90.00.02.01.6-0.51.60.00.01.21.71.6
Time in open arm after self-admin0.70.81.90.0-0.10.61.2-1.00.00.01.11.3-1.01.30.00.01.41.31.0
Sum of active levers in priming session hrs 5-61.71.63.70.0-1.91.31.8-1.70.00.01.91.7-0.61.10.00.01.31.71.3
Time to tail flick, vehicle, before self-admin0.50.52.10.00.41.40.7-0.80.00.00.70.5-1.01.00.00.00.70.91.0
Time to tail flick, vehicle, after self-admin0.00.00.20.0-0.00.2-0.10.30.00.0-0.3-0.0-0.40.00.00.00.1-0.1-0.1
Time to tail flick, test, before self-admin1.41.42.60.0-1.11.51.6-1.50.00.01.61.6-1.11.40.00.01.41.61.3
Time to tail flick, test, after self-admin0.20.22.00.01.4-0.0-0.60.50.00.0-0.7-0.5-0.50.10.00.0-0.1-0.4-0.1
Delta time to tail flick, vehicle, before/after SA1.21.22.60.00.4-1.5-1.51.60.00.0-1.6-1.10.7-1.40.00.0-1.0-1.5-1.4
Delta time to tail flick, test, before/after SA1.21.13.20.01.8-1.2-1.51.30.00.0-1.5-1.40.5-0.80.00.0-1.0-1.3-0.9
Ambulatory time before self-admin0.60.71.9-1.31.30.10.4-0.3-1.01.00.50.6-0.60.3-1.31.40.30.40.3
Ambulatory time after self-admin0.10.10.70.0-0.9-0.30.1-0.00.00.00.10.10.3-0.20.00.0-0.10.0-0.3
Total heroin consumption1.31.63.2-1.21.21.21.5-1.8-0.50.51.71.1-0.71.4-1.41.30.71.51.5
Area under the delay curve3.03.26.2-0.50.51.92.4-2.40.1-0.12.42.5-2.02.1-0.40.62.12.32.2
Delay disc. indifference point, 0s delay0.40.40.9-0.70.7-0.5-0.70.7-0.90.9-0.8-0.60.0-0.6-0.60.6-0.4-0.6-0.5
Delay disc. indifference point, 16s delay2.12.15.3-0.70.71.32.1-2.20.4-0.42.32.1-1.11.4-0.80.81.31.91.5
Delay disc. indifference point, 2s delay2.62.95.5-0.40.42.32.0-2.1-0.30.31.82.0-2.32.2-0.20.42.32.12.3
Delay disc. indifference point, 24s delay2.62.53.51.5-1.51.51.8-1.71.9-1.91.81.8-0.91.41.5-1.41.51.71.5
Delay disc. indifference point, 4s delay0.90.92.2-1.51.50.40.6-0.6-1.11.10.60.7-0.90.5-1.41.50.50.60.6
Delay disc. indifference point, 8s delay1.71.73.80.3-0.31.11.8-1.70.8-0.81.82.0-1.31.50.4-0.21.71.71.6
Delay discount exponential model param3.33.46.70.3-0.3-2.0-2.52.5-0.30.3-2.5-2.62.1-2.20.2-0.4-2.3-2.4-2.3
Delay discount hyperbolic model param3.13.36.10.4-0.4-2.0-2.42.4-0.20.2-2.3-2.52.1-2.10.3-0.5-2.2-2.3-2.3
Fecal boli incidents, locomotor time 11.41.52.51.4-1.40.51.3-1.21.6-1.61.31.4-0.40.91.4-1.31.21.20.9
Change in fecal boli incidents, locomotor task0.90.81.5-0.80.8-0.7-0.81.0-0.70.7-0.7-0.90.7-1.2-1.01.0-1.2-0.9-1.2
Time >=10cm from walls, locomotor time 10.50.51.10.9-0.9-1.0-0.30.50.9-0.9-0.3-0.10.8-0.70.8-0.9-0.3-0.4-0.6
Bouts of movement, locomotor time 11.61.84.31.7-1.7-1.4-0.40.72.1-2.1-0.4-0.41.6-1.21.6-1.7-0.9-0.8-1.1
Total resting periods, locomotor time 12.62.96.32.4-2.4-1.6-0.60.82.5-2.5-0.5-0.51.8-1.22.3-2.3-0.9-0.9-1.2
Rest time, locomotor task time 10.91.02.91.6-1.6-0.40.3-0.21.5-1.50.20.50.10.21.7-1.60.60.20.2
Distance moved, locomotor task time 12.32.56.2-2.52.51.30.1-0.2-2.52.50.1-0.1-1.20.4-2.52.50.00.30.4
Vertical activity count, locomotor time 13.63.89.3-2.82.81.50.4-0.7-3.13.10.30.4-1.91.1-2.72.80.80.81.1
Time >=10cm from walls, locomotor time 21.61.74.52.1-2.10.30.5-0.41.8-1.80.40.8-0.40.52.1-2.01.00.50.5
Bouts of movement, locomotor time 23.84.05.71.8-1.8-2.0-2.12.21.3-1.3-2.1-2.22.4-2.31.6-1.8-2.2-2.3-2.3
Total resting periods, locomotor time 23.53.75.51.6-1.6-2.0-2.02.11.2-1.2-2.0-2.12.3-2.31.5-1.6-2.2-2.2-2.2
Rest time, locomotor task time 20.40.41.10.9-0.9-0.7-0.10.01.1-1.1-0.1-0.20.8-0.20.9-0.9-0.3-0.2-0.2
Distance moved, locomotor task time 21.82.04.1-1.91.91.50.6-0.7-2.02.00.50.7-1.81.0-1.71.81.00.91.0
Vertical activity count, locomotor time 23.63.911.1-2.92.81.30.2-0.4-3.33.30.00.4-2.11.1-2.62.71.00.71.0
Weight adjusted by age1.71.83.3-0.00.0-1.8-1.81.8-0.40.4-1.7-1.71.6-1.6-0.0-0.1-1.6-1.7-1.8
Seeking ratio, delayed vs. immediate footshock0.30.41.0-0.90.90.50.5-0.5-0.50.50.60.3-0.30.2-1.01.00.00.50.2
Locomotion in novel chamber1.31.63.4-1.41.41.50.8-0.8-1.51.50.71.0-1.81.1-1.21.31.21.01.1
Locomotion in novel chamber post-restriction0.40.40.7-0.50.5-0.5-0.70.8-0.60.6-0.7-0.80.5-0.7-0.60.5-0.8-0.7-0.7
Progressive ratio0.10.10.3-0.20.20.30.4-0.5-0.00.00.50.2-0.10.3-0.30.30.20.50.5
Food seeking constrained by brief footshock1.21.54.0-0.60.61.71.2-1.2-0.70.71.01.3-2.01.5-0.40.61.71.41.6
Seeking ratio, punishment vs. effort0.30.31.2-0.40.40.80.5-0.3-0.50.50.30.7-1.10.7-0.20.30.90.50.6
Run reversals in cocaine runway, females2.02.02.8-1.61.6-1.2-1.31.2-1.71.7-1.2-1.51.0-1.3-1.61.5-1.4-1.3-1.2
Run reversals in cocaine runway, males1.11.13.3-1.71.80.40.3-0.4-1.41.40.40.3-0.50.3-1.81.80.10.30.3
Latency to leave start box in cocaine runway0.20.20.80.3-0.3-0.00.5-0.50.9-0.90.70.40.3-0.20.1-0.2-0.10.30.1
Latency to leave start box in cocaine runway, F0.20.30.60.5-0.5-0.8-0.30.30.7-0.7-0.2-0.30.8-0.60.4-0.4-0.5-0.4-0.5
Latency to leave start box in cocaine runway, M0.90.81.80.5-0.51.21.2-1.11.1-1.11.31.1-0.50.60.4-0.40.61.10.8
Cd content in liver1.01.11.61.3-1.3-0.9-0.90.91.1-1.1-0.9-0.91.1-1.01.2-1.3-0.9-0.9-1.0
Co content in liver0.10.10.2-0.20.30.10.4-0.20.1-0.10.40.5-0.20.2-0.30.30.20.30.0
Cu content in liver0.30.31.3-0.91.0-0.20.4-0.2-0.20.20.60.30.3-0.0-1.11.1-0.30.1-0.3
Fe content in liver0.60.72.01.1-1.10.30.6-0.61.4-1.40.70.40.40.51.0-1.10.10.50.3
K content in liver1.11.12.5-0.10.1-1.5-1.01.20.2-0.2-0.9-1.11.6-1.5-0.20.1-1.5-1.3-1.5
Mg content in liver0.60.61.60.6-0.6-1.0-0.40.61.0-1.0-0.2-0.41.2-1.00.4-0.5-0.9-0.6-1.0
Mn content in liver1.21.42.11.4-1.4-1.2-0.91.01.3-1.3-0.9-0.81.3-1.21.4-1.4-0.9-1.1-1.1
Na content in liver2.12.22.8-1.41.5-1.6-1.51.5-1.41.4-1.4-1.51.3-1.5-1.51.4-1.7-1.6-1.6
Rb content in liver1.41.74.3-0.50.5-1.9-1.01.30.2-0.2-0.8-1.12.1-1.9-0.80.7-1.9-1.4-1.9
Se content in liver1.21.42.70.2-0.2-1.6-1.51.60.0-0.0-1.5-1.41.4-1.50.2-0.3-1.5-1.5-1.6
Sr content in liver1.21.12.6-0.10.11.60.9-1.2-0.60.60.80.8-1.61.50.10.01.41.21.5
Zn content in liver0.30.41.10.8-0.80.30.6-0.51.1-1.10.60.40.10.40.7-0.70.20.40.3