Hub : Genes

Plekhd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000038297 0.2 0.08 1.7e-09 0.1 0.16 0.11 0.14 3.7e-06 8.7e-09 1.7e-06 8.3e-08
2 BLA mRNA stability ENSRNOG00000038297 0.78 0.03 0.0e+00 0.4 0.44 0.44 0.43 4.6e-23 7.8e-26 1.3e-25 4.7e-25
3 Brain gene expression ENSRNOG00000038297 0.24 0.08 0.0e+00 0.18 0.23 0.24 0.24 1.8e-16 2.5e-21 1.7e-22 4.9e-22
4 Brain intron excision ratio chr6:100355056:100355237 0.12 0.08 7.1e-03 0.03 0.02 0.01 0.01 1.4e-03 1.1e-02 2.9e-02 1.4e-02
5 Brain mRNA stability ENSRNOG00000038297 0.54 0.1 0.0e+00 0.55 0.57 0.58 0.58 2.9e-61 8.0e-64 3.0e-66 2.1e-66
6 IL mRNA stability ENSRNOG00000038297 0.45 0.13 3.1e-09 0.27 0.3 0.3 0.31 3.0e-07 5.3e-08 6.9e-08 4.4e-08
7 LHb gene expression ENSRNOG00000038297 0.51 0.13 1.7e-09 0.3 0.32 0.31 0.3 8.3e-08 2.9e-08 4.3e-08 9.5e-08
8 LHb mRNA stability ENSRNOG00000038297 0.56 0.12 5.2e-14 0.38 0.5 0.48 0.49 4.8e-10 8.2e-14 5.3e-13 1.8e-13
9 Liver gene expression ENSRNOG00000038297 0.03 0.02 5.8e-03 0.01 0 0 0 4.1e-02 8.9e-02 1.6e-01 1.4e-01
10 NAcc gene expression ENSRNOG00000038297 0.16 0.07 3.6e-10 0.03 0.1 0.09 0.08 3.1e-03 5.7e-08 3.1e-07 1.7e-06
11 NAcc mRNA stability ENSRNOG00000038297 0.41 0.11 0.0e+00 0.23 0.22 0.22 0.24 6.3e-17 1.1e-16 3.0e-16 9.6e-18
12 OFC gene expression ENSRNOG00000038297 0.21 0.1 1.3e-03 0.13 0.07 0.03 0.07 5.4e-04 9.7e-03 7.6e-02 1.0e-02
13 OFC mRNA stability ENSRNOG00000038297 0.5 0.14 3.0e-08 0.21 0.22 0.17 0.18 1.2e-05 5.2e-06 6.5e-05 4.4e-05
14 PL gene expression ENSRNOG00000038297 0.11 0.05 7.4e-08 0.09 0.07 0.06 0.07 1.9e-07 2.4e-06 2.3e-05 3.2e-06
15 PL mRNA stability ENSRNOG00000038297 0.49 0.09 0.0e+00 0.38 0.38 0.37 0.37 1.3e-30 3.2e-30 1.8e-29 1.1e-29

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.51.87.1-0.6-0.41.12.3-1.1-0.41.3-0.80.9-0.5-0.7-1.9-1.7-2.7-0.9
BMI without tail1.12.27.01.51.52.12.60.71.21.71.42.31.61.3-0.00.3-0.30.8
Body weight1.87.822.54.22.24.32.71.11.43.42.94.73.22.51.40.91.41.4
Epididymis fat weight0.00.10.50.10.10.00.40.20.50.00.20.70.20.2-0.4-0.10.10.0
Glucose1.31.96.8-1.8-1.2-2.3-1.4-0.3-0.7-2.0-1.2-2.6-1.5-1.1-0.1-0.00.2-0.4
Heart weight0.60.92.71.30.90.90.10.80.50.71.11.61.11.20.70.60.50.9
Left kidney weight0.20.72.10.40.2-0.8-1.40.70.3-0.90.5-0.50.30.41.31.11.50.8
Right kidney weight0.30.93.90.7-0.1-0.5-1.80.3-0.1-0.70.5-0.80.30.22.01.31.50.8
Tail length3.911.824.85.03.13.00.72.82.41.74.13.74.13.74.03.34.43.0
Length with tail3.211.828.95.42.83.91.42.31.92.64.04.44.13.53.52.84.22.4
Length without tail0.81.64.92.20.61.90.80.30.21.61.32.11.30.91.00.61.60.4
Liver weight, left0.00.10.2-0.00.2-0.3-0.20.30.4-0.40.2-0.10.20.20.30.3-0.40.4
Liver weight, right1.22.15.2-0.01.3-1.70.11.92.3-2.01.40.00.91.41.02.10.71.7
Parametrial fat weight0.20.51.50.50.4-0.3-0.90.70.4-0.50.60.30.60.71.20.90.70.9
Retroperitoneal fat weight0.51.63.6-0.7-1.00.81.0-1.4-0.81.2-1.20.6-0.9-1.1-1.9-1.9-1.9-1.6
Intraocular pressure1.82.54.3-1.5-1.70.11.1-1.9-2.10.7-2.0-1.1-1.9-1.9-1.9-1.7-0.9-1.9
Extensor digitorum longus weight0.20.71.51.20.80.90.10.50.70.61.01.01.00.90.90.70.80.6
Soleus weight1.75.110.83.22.42.41.71.61.91.62.73.32.72.51.71.81.31.6
Tibialis anterior weight1.34.515.83.51.14.01.90.10.43.51.73.52.11.41.00.10.50.3
Tibia length0.31.02.80.7-1.40.5-1.0-1.1-1.70.7-0.7-0.9-0.8-0.91.2-0.31.4-0.6
Number of licking bursts1.92.35.5-2.4-1.3-1.80.6-0.9-0.7-1.2-1.6-1.9-1.9-1.5-1.7-0.8-1.8-1.2
Food consumed during 24 hour testing period0.70.82.41.00.90.61.50.51.10.31.21.41.00.90.31.0-0.10.5
Times rat made contact with spout1.61.83.31.31.80.81.31.31.60.11.81.71.71.50.61.40.51.2
Mean time between licks in bursts1.82.56.0-2.3-1.6-2.0-1.6-1.1-1.3-1.5-1.9-2.5-1.9-1.6-0.6-0.8-0.4-0.9
Mean num. licks in bursts3.74.58.12.92.42.10.61.61.81.12.62.92.82.41.81.71.81.9
Std. dev. time between licks in bursts0.91.13.6-1.4-0.8-1.5-1.6-0.4-0.5-1.1-1.1-1.9-1.1-0.9-0.2-0.5-0.1-0.2
Water consumed over 24 hours1.41.67.81.11.21.62.80.31.01.11.22.01.10.8-0.60.4-0.90.1
Indifference point 0 sec0.50.91.71.31.10.90.60.71.20.51.21.31.20.80.50.70.70.6
Indifference point AUC0.20.31.20.8-0.10.2-0.70.1-0.10.10.30.30.30.11.00.41.10.3
Indifference point function ln k0.50.74.30.50.61.12.10.00.50.80.61.00.50.3-0.70.1-1.2-0.1
Indifference point function log k0.50.74.30.50.61.12.10.00.50.80.61.00.50.3-0.70.1-1.2-0.1
Delay discounting total patch changes 0 sec0.61.02.51.41.11.21.00.61.10.81.21.61.30.80.30.50.40.6
Delay discounting total patch changes 12 sec1.41.94.31.71.30.7-0.01.21.30.21.71.41.61.31.61.42.11.4
Delay discounting total patch changes 18 sec0.70.92.11.11.00.30.00.81.0-0.11.21.01.20.81.11.01.51.0
Delay discounting total patch changes 24 sec1.41.85.62.30.81.5-0.10.50.41.01.41.11.40.91.91.12.40.8
Delay discounting total patch changes 6 sec0.20.41.00.80.50.1-0.20.50.5-0.00.70.00.60.40.90.81.00.6
Delay discounting time to switch 0 sec0.91.45.3-0.50.2-1.7-2.30.90.4-1.70.1-1.40.00.41.41.01.90.9
Delay discounting water rate 0 sec1.42.29.91.50.72.53.1-0.40.02.20.82.00.90.4-0.8-0.3-1.8-0.4
Delay discounting water rate 12 sec0.91.42.60.1-1.01.31.4-1.5-1.41.6-0.80.1-0.7-1.0-1.2-1.4-1.6-1.2
Delay discounting water rate 18 sec2.33.09.91.2-0.73.02.7-1.7-1.63.1-0.51.0-0.2-0.6-1.2-1.6-1.8-1.5
Delay discounting water rate 24 sec2.53.510.00.9-1.02.92.8-1.9-1.93.2-0.81.4-0.4-1.0-1.7-2.1-1.7-1.7
Delay discounting water rate 6 sec1.52.27.72.21.12.82.10.20.42.31.22.21.51.10.10.10.20.1
Locomotor activity0.60.93.81.40.21.91.3-0.4-0.51.90.41.20.60.20.1-0.3-0.1-0.4
Locomotor testing distance0.71.13.80.6-0.51.81.0-1.2-1.31.9-0.50.5-0.2-0.7-0.7-1.2-0.5-1.2
Locomotor testing rearing0.40.62.71.20.31.60.2-0.3-0.41.50.30.80.60.3-0.0-0.4-0.1-0.3
Light reinforcement 12.24.117.83.00.24.22.6-0.8-1.23.90.82.61.10.50.5-0.60.6-0.8
Light reinforcement 21.21.65.50.6-0.91.92.3-1.3-1.62.0-0.50.5-0.6-0.7-0.7-1.0-1.0-1.3
Reaction time number correct4.36.210.6-2.1-2.70.10.6-3.0-2.81.0-2.9-2.1-2.7-2.8-2.6-3.0-3.3-2.9
Reaction time mean minus median0.40.52.0-0.90.3-1.4-0.90.70.7-1.30.0-0.2-0.10.4-0.30.4-0.20.5
Reaction time mean minus median AUC0.30.41.8-0.80.1-1.4-0.80.50.6-1.2-0.1-0.3-0.20.2-0.30.3-0.00.4
Reaction time num false alarms1.72.35.1-1.1-1.20.51.7-1.6-1.11.0-1.5-0.8-1.4-1.4-2.2-1.9-2.3-1.9
Reaction time num false alarms AUC1.72.45.7-1.0-1.20.71.6-1.7-1.21.2-1.6-0.7-1.4-1.4-2.3-2.0-2.4-1.9
Reaction time trials correct on left4.36.210.6-2.1-2.70.10.6-3.0-2.81.0-2.9-2.1-2.7-2.8-2.6-3.0-3.3-2.9
Reaction time trials on left4.46.211.4-2.2-2.60.00.6-2.9-2.70.9-3.0-2.1-2.7-2.8-2.7-3.0-3.4-2.9
Reaction time mean1.01.33.6-0.01.5-0.9-0.31.61.9-1.21.21.01.11.5-0.01.20.41.4
Reaction time mean AUC1.21.64.3-0.11.6-1.2-0.51.82.1-1.51.20.81.11.60.01.30.41.5
Median of all reaction times1.11.53.70.31.6-0.5-0.01.71.9-0.91.31.31.31.60.11.20.61.4
Reaction time omissions1.21.64.4-2.10.8-2.1-0.60.81.6-2.1-0.2-0.9-0.20.2-1.70.0-1.60.2
Reaction time false alarm rate0.20.31.70.10.10.71.3-0.20.10.8-0.10.5-0.0-0.0-0.9-0.5-0.7-0.5
Reaction time premature initiation rate0.91.22.81.11.20.3-0.41.21.1-0.11.31.71.51.41.01.00.91.1
Reaction time premature initiations0.10.20.7-0.0-0.20.40.0-0.4-0.50.5-0.30.4-0.0-0.2-0.5-0.7-0.8-0.4
Std. dev. reaction times0.50.72.8-1.20.5-1.7-0.70.81.1-1.50.0-0.1-0.10.5-0.80.3-0.50.5
Reaction time trials completed4.46.211.4-2.2-2.60.00.6-2.9-2.70.9-3.0-2.1-2.7-2.8-2.7-3.0-3.4-2.9
Reaction time trials AUC4.86.811.2-2.2-2.80.10.8-3.1-2.81.1-3.1-2.1-2.9-3.0-2.9-3.2-3.3-3.1
Social response proportion0.50.50.90.60.6-0.3-0.90.80.6-0.50.90.50.80.90.80.90.20.9
Social responses0.20.31.00.3-0.60.5-0.2-0.6-0.80.8-0.40.1-0.3-0.3-0.3-0.7-1.0-0.5
Social time0.60.82.4-0.30.4-1.4-1.10.70.4-1.50.5-1.00.10.50.91.30.40.9
Conditioned locomotion0.70.94.4-0.5-0.3-1.5-2.10.5-0.2-1.4-0.2-1.6-0.4-0.11.10.60.20.4
Cocaine response after cond. corrected1.21.35.1-1.4-0.2-2.3-1.60.50.1-2.1-0.5-2.0-0.7-0.20.40.60.60.3
Cocaine response after cond. not corrected1.01.14.0-1.4-0.5-2.0-1.50.3-0.2-1.8-0.7-1.9-0.8-0.30.10.30.40.1
Cocaine response before conditioning0.10.20.50.2-0.00.60.6-0.10.00.70.00.70.10.1-0.5-0.4-0.4-0.3
Saline control response0.40.51.1-0.2-0.80.4-0.7-1.0-1.00.6-0.8-0.4-0.6-0.7-0.5-1.0-0.5-1.0
Condit. Reinf. active minus inactive responses2.73.37.0-0.5-1.31.62.6-2.1-1.52.0-1.40.2-1.2-1.5-2.6-2.3-2.1-2.3
Condit. Reinf. active-inactive response ratio1.11.23.40.3-0.51.51.8-1.1-0.71.7-0.50.7-0.3-0.5-1.3-1.2-1.1-1.2
Condit. Reinf. active responses0.81.12.80.3-0.61.51.7-1.2-0.81.7-0.50.5-0.3-0.6-1.4-1.2-0.8-1.3
Condit. Reinf. inactive responses0.10.10.2-0.2-0.5-0.4-0.4-0.3-0.2-0.3-0.2-0.4-0.3-0.3-0.1-0.00.3-0.3
Condit. Reinf. lever presses0.60.81.71.11.10.80.30.71.20.51.21.01.31.10.30.50.80.8
Condit. Reinf. lever reinforcers received1.01.43.20.3-0.71.61.7-1.3-0.81.8-0.60.6-0.3-0.7-1.6-1.5-0.9-1.5
Pavlov. Cond. lever latency0.30.40.9-1.0-0.5-0.9-0.5-0.1-0.6-0.7-0.7-0.9-0.8-0.4-0.1-0.10.2-0.4
Pavlov. Cond. magazine entry latency0.40.42.10.1-0.10.71.4-0.20.00.8-0.10.4-0.1-0.1-0.9-0.6-1.2-0.4
Pavlov. Cond. change in total contacts0.20.31.00.60.01.00.8-0.30.11.00.20.80.30.0-0.5-0.5-0.6-0.1
Pavlov. Cond. index score0.20.31.10.30.10.81.0-0.20.20.80.10.40.2-0.0-0.7-0.5-1.0-0.2
Pavlov. Cond. latency score0.20.31.00.40.10.91.0-0.20.10.90.10.40.20.0-0.6-0.5-0.9-0.2
Pavlov. Cond. lever contacts0.20.31.11.00.40.90.20.10.40.80.60.50.70.40.30.00.20.3
Pavlov. Cond. magazine entry number1.21.53.20.11.0-1.2-1.41.31.1-1.61.0-0.20.81.01.51.71.81.3
Pavlov. Cond. intertrial magazine entries0.30.41.0-0.0-1.00.30.7-1.0-0.90.5-0.5-0.1-0.7-0.8-0.4-0.4-0.3-1.0
Pavlov. Cond. lever-magazine prob. diff.0.20.31.30.20.00.71.0-0.20.10.80.00.40.1-0.1-0.7-0.6-1.2-0.2
Pavlov. Cond. response bias0.20.20.90.5-0.20.90.4-0.4-0.10.9-0.00.30.1-0.2-0.3-0.6-0.7-0.3
Conditioned reinforcement - actives1.91.93.9-0.1-1.91.00.4-1.9-2.01.4-1.3-0.1-1.3-1.7-1.0-1.6-0.7-1.9
Conditioned reinforcement - inactives1.51.82.8-1.5-1.4-0.8-0.7-1.3-1.7-0.4-1.6-1.5-1.6-1.6-1.2-1.2-1.2-1.4
Conditioned locomotion1.41.73.2-1.5-1.8-1.1-0.5-1.2-1.7-0.6-1.6-1.5-1.7-1.6-0.7-1.0-0.5-1.1
Intermittent access intake day 1-15 change2.92.94.8-1.8-2.1-0.9-1.0-1.7-1.7-0.1-2.2-1.8-2.1-2.1-1.6-1.9-1.1-1.9
Intermittent access intake escalation4.34.27.8-1.7-2.8-0.6-1.2-2.4-2.50.4-2.6-1.9-2.5-2.6-1.5-2.4-1.2-2.4
Intermittent access intake escalation 22.62.64.9-1.3-2.2-0.6-1.8-1.8-2.10.1-2.1-1.7-1.9-2.1-0.8-1.7-0.4-1.8
Intermitt. access day 1 inactive lever presses0.20.31.50.4-0.10.91.2-0.4-0.30.8-0.00.20.1-0.1-0.2-0.30.4-0.3
Intermitt. access day 15 inactive lever presses1.71.94.0-0.7-1.40.80.6-1.8-2.01.3-1.6-0.6-1.3-1.6-1.4-1.9-0.5-1.7
Intermitt. access escalation Index0.20.20.5-0.2-0.50.20.2-0.7-0.50.5-0.4-0.1-0.5-0.4-0.4-0.5-0.1-0.5
Intermittent access day 1 total infusions0.81.02.00.51.1-0.30.91.21.1-0.81.20.50.91.00.71.41.11.1
Intermittent access day 15 total infusions1.01.12.1-1.1-1.5-0.70.0-1.2-1.1-0.2-1.3-1.1-1.4-1.4-0.9-0.9-0.5-1.2
Intermittent access terminal intake (last 3 days)0.50.51.1-0.8-1.0-0.6-0.0-0.7-0.9-0.3-0.8-0.8-1.0-1.0-0.6-0.5-0.1-0.8
Intermittent access total infusions0.10.10.5-0.5-0.2-0.70.40.10.1-0.6-0.0-0.3-0.3-0.2-0.30.30.2-0.1
Intermittent access day 1 locomotion0.50.52.4-0.20.7-0.61.60.80.9-0.80.60.40.40.6-0.20.80.10.7
Intermittent access day 15 total locomotion0.40.40.8-0.5-0.9-0.00.9-0.8-0.60.2-0.7-0.1-0.8-0.8-0.7-0.6-0.6-0.7
Intermittent access total locomotion0.10.20.6-0.6-0.3-0.70.70.00.0-0.6-0.1-0.3-0.4-0.2-0.30.20.00.1
Intermittent access standard deviation1.31.42.5-1.4-1.4-1.2-1.3-0.8-1.2-0.6-1.5-1.6-1.4-1.3-0.7-1.00.0-1.0
Cocaine induced anxiety5.15.99.6-2.4-2.9-1.0-1.4-2.8-3.0-0.0-3.1-2.8-2.9-3.0-1.8-2.6-1.6-2.6
Post-drug Anxiety1.71.93.3-1.0-1.7-0.2-1.6-1.7-1.80.3-1.7-1.5-1.5-1.7-0.7-1.5-0.7-1.5
Baseline Anxiety2.32.44.11.51.90.4-0.61.92.0-0.21.91.51.92.01.51.61.01.8
Lifetime Intake0.10.10.4-0.3-0.5-0.6-0.4-0.2-0.3-0.5-0.3-0.4-0.5-0.4-0.00.00.4-0.2
Incentive Sensitization - Responses0.40.42.5-0.2-0.40.31.6-0.4-0.30.5-0.30.1-0.5-0.5-0.9-0.4-0.3-0.7
Incentive Sensitization - Breakpoint0.50.53.0-0.2-0.40.41.7-0.5-0.40.6-0.30.2-0.6-0.5-1.0-0.5-0.3-0.8
Progressive ratio test 1 active lever presses0.50.51.00.20.9-0.30.60.91.0-0.60.90.30.70.70.21.00.80.8
Progressive ratio test 1 breakpoint0.70.71.40.41.0-0.10.91.11.1-0.51.10.50.80.90.41.20.90.9
Progressive ratio test 1 inactive lever presses0.40.41.60.60.50.1-0.40.60.3-0.20.60.20.60.60.90.71.30.8
Progressive ratio test 2 active lever presses0.20.20.8-0.3-0.4-0.00.9-0.3-0.30.0-0.3-0.2-0.5-0.5-0.6-0.2-0.1-0.5
Progressive ratio test 2 breakpoint0.10.11.5-0.1-0.10.31.2-0.00.00.20.00.2-0.1-0.2-0.6-0.00.2-0.3
Progressive ratio test 2 inactive lever presses0.50.51.1-0.9-0.9-0.40.1-0.7-1.1-0.1-0.9-0.8-0.9-0.9-0.7-0.70.0-0.7
Total sessions with >9 infusions0.70.82.81.30.30.5-0.60.70.30.30.91.00.90.81.40.81.70.7
Short access day 1 total inactive lever presses0.00.00.10.1-0.20.1-0.2-0.00.00.10.10.20.00.00.10.10.4-0.0
Short access day 10 total inactive lever presses1.51.63.2-1.0-1.50.30.4-1.6-1.80.9-1.6-0.8-1.4-1.5-1.3-1.7-0.4-1.5
Short access day 1 total infusions0.30.31.30.7-0.10.2-1.10.1-0.10.20.40.60.30.20.70.31.10.1
Short access day 10 total infusions0.60.72.10.40.8-0.6-0.21.00.9-0.81.00.30.60.80.71.21.41.0
Short access total infusions0.20.21.10.20.1-0.3-0.80.30.3-0.40.30.20.20.30.50.41.00.3
Short access day 1 locomotion0.10.10.3-0.10.2-0.5-0.40.40.5-0.50.20.30.20.30.10.30.00.4
Short access day 10 total locomotion0.30.31.00.50.30.00.20.60.3-0.00.60.70.50.70.60.51.00.7
Short access total locomotion0.30.30.80.70.30.20.20.60.40.10.60.90.60.70.60.50.70.7
Compulsive drug intake0.60.62.51.10.31.60.5-0.20.21.40.41.30.70.40.3-0.3-0.60.1
One hour access (0.3 mA shock)0.50.61.80.4-1.20.8-0.0-1.1-1.31.1-0.70.0-0.6-0.80.1-0.8-0.1-0.7
One hour access (shock baseline)0.50.51.9-0.2-1.2-0.2-0.3-0.8-1.40.1-0.7-0.7-0.9-0.90.2-0.40.5-0.7
Number of responses in last shaping day1.21.22.11.11.20.40.41.21.4-0.01.41.21.31.30.81.30.91.2
Context. condit. distance diff. score0.30.41.41.1-0.31.20.1-0.4-0.51.10.21.00.40.10.5-0.10.4-0.2
Locomotion velocity, session 10.10.10.8-0.40.0-0.6-0.90.30.2-0.6-0.1-0.3-0.00.00.10.0-0.30.2
Locomotion distance, session 11.21.63.3-1.5-1.0-0.10.5-1.2-1.20.3-1.5-0.6-1.3-1.4-1.8-1.6-1.8-1.5
Locomotion velocity, session 20.70.92.1-0.4-1.5-0.1-1.2-1.2-1.40.3-1.2-0.4-1.1-1.0-0.0-1.0-0.3-0.9
Locomotion distance, session 21.92.74.7-2.0-1.6-0.5-0.1-1.8-1.70.2-2.2-1.3-1.9-1.9-1.9-2.0-1.7-1.9
Locomotion velocity, session 30.91.04.20.8-0.60.0-2.1-0.5-1.1-0.1-0.1-1.0-0.1-0.31.90.61.90.2
Locomotion distance, session 30.80.91.80.50.9-0.4-0.91.10.8-0.80.9-0.30.80.91.41.31.11.1
Stereotopy head waving bouts, day 31.11.42.31.41.20.4-0.11.11.1-0.11.50.71.41.41.51.51.41.2
Stereotopy head waving duration, day 30.70.92.61.20.60.2-1.10.60.5-0.11.00.30.90.91.61.11.50.9
Locomotion velocity, session 70.80.92.8-0.7-0.6-1.6-1.7-0.0-0.3-1.5-0.3-1.6-0.6-0.40.80.60.60.2
Locomotion distance, session 71.01.32.0-1.1-1.4-0.30.3-1.2-1.30.2-1.4-1.0-1.4-1.4-1.1-1.2-1.4-1.3
Stereotopy head waving bouts, day 72.52.87.02.61.41.7-0.11.10.80.92.01.42.01.72.31.72.11.5
Stereotopy head waving duration, day 72.63.28.83.01.42.0-0.21.00.71.42.11.82.21.72.41.42.21.5
Locomotion velocity, session 80.60.81.7-0.4-1.10.4-0.6-1.2-1.20.7-1.0-0.5-0.7-0.9-0.7-1.3-0.6-1.0
Locomotion distance, session 80.81.22.5-0.5-1.30.70.4-1.6-1.61.1-1.3-0.0-1.0-1.2-1.0-1.4-0.8-1.4
Degree of sensitization distance1.71.72.8-0.8-1.60.40.9-1.6-1.40.9-1.4-0.3-1.3-1.5-1.5-1.6-1.5-1.7
Degree of sensitization stereotypy2.02.15.52.31.31.70.10.90.71.11.71.51.81.51.81.21.71.2
Condit. Reinf. active minus inactive responses1.01.14.81.60.42.21.2-0.3-0.31.90.61.50.90.40.2-0.2-0.1-0.1
Condit. Reinf. active-inactive response ratio1.01.13.41.70.61.81.00.10.11.50.91.51.20.80.60.30.60.3
Condit. Reinf. active responses1.01.24.00.9-0.32.01.8-1.0-0.91.9-0.11.00.1-0.5-0.7-0.9-0.9-0.9
Condit. Reinf. inactive responses2.02.45.3-1.2-1.30.41.9-1.6-1.30.9-1.5-0.2-1.5-1.7-2.3-1.8-2.2-1.9
Incentive salience index mean0.50.62.51.20.31.61.1-0.2-0.21.40.51.30.70.3-0.0-0.20.0-0.1
Condit. Reinf. lever presses0.10.10.70.20.30.20.70.20.50.20.30.80.30.3-0.40.00.30.1
Time in familiar zone, hab. session 10.40.41.10.50.70.2-0.90.50.4-0.20.60.40.80.71.00.70.40.8
Time in novel zone, hab. session 10.40.40.9-0.3-0.9-0.2-0.1-0.8-0.70.1-0.7-0.8-0.9-1.0-0.5-0.60.2-0.8
Total zone transitions, hab. session 10.30.52.0-1.4-0.1-1.0-0.1-0.20.1-0.9-0.7-0.5-0.6-0.5-1.1-0.5-0.7-0.3
Total locomotion distance, hab. session 12.13.08.7-2.9-1.3-1.9-0.4-1.1-0.8-1.3-2.1-1.9-2.0-1.8-2.2-1.5-1.9-1.3
Locomotion velocity, hab. session 11.62.47.1-2.7-1.0-1.70.2-0.9-0.6-1.1-1.8-1.5-1.8-1.5-2.2-1.3-1.7-1.2
Time in familiar zone, hab. session 20.80.82.40.61.20.51.00.91.20.11.01.51.11.10.20.70.10.9
Time in novel zone, hab. session 21.31.32.5-0.6-1.50.1-0.3-1.5-1.60.6-1.4-1.2-1.3-1.5-0.8-1.3-0.4-1.5
Total zone transitions, hab. session 20.70.92.2-0.7-0.40.61.2-0.9-0.50.9-0.80.8-0.5-0.7-1.5-1.3-1.3-1.0
Total locomotion distance, hab. session 22.12.76.2-1.9-1.4-0.11.1-1.7-1.30.6-2.0-0.2-1.7-1.7-2.5-2.2-2.2-1.9
Locomotion velocity, hab. session 22.12.85.4-1.8-1.5-0.00.9-1.8-1.50.7-2.0-0.3-1.8-1.8-2.3-2.2-2.1-2.0
Novel to familiar place preference ratio2.83.06.8-0.8-2.5-1.0-2.6-1.8-2.4-0.3-1.9-2.2-1.9-1.90.4-1.11.3-1.5
Novelty place preference2.42.58.6-0.5-2.2-0.9-2.9-1.5-2.1-0.3-1.5-1.9-1.5-1.50.8-0.81.8-1.1
Time in novel zone, NPP test2.22.37.1-0.5-2.2-0.9-2.7-1.4-2.0-0.3-1.5-1.8-1.5-1.50.6-0.81.7-1.1
Total zone transitions, NPP test0.40.62.2-0.50.40.51.1-0.10.40.6-0.31.10.10.0-1.5-0.9-1.3-0.3
Total locomotion distance, NPP test0.40.52.1-0.9-0.2-0.11.0-0.4-0.10.2-0.70.1-0.6-0.5-1.4-0.9-1.2-0.7
Locomotion velocity, NPP test0.40.51.6-0.8-0.40.01.0-0.5-0.30.3-0.70.0-0.7-0.6-1.3-0.9-1.1-0.7
Pavlov. Cond. lever latency0.30.31.8-0.2-0.3-0.5-0.8-0.2-0.6-0.6-0.2-1.3-0.4-0.40.90.50.40.0
Pavlov. Cond. magazine entry latency0.50.62.00.21.0-0.2-0.41.11.4-0.30.81.10.91.1-0.00.40.20.9
Pavlov. Cond. change in total contacts0.80.84.10.50.90.60.90.81.20.60.72.00.90.8-0.7-0.2-0.70.5
Pavlov. Cond. index score0.30.42.30.50.50.60.10.60.80.60.51.50.70.7-0.3-0.20.10.3
Pavlov. Cond. latency score0.30.42.00.70.50.60.00.50.70.60.51.40.70.7-0.1-0.10.30.3
Pavlov. Cond. lever contacts0.30.32.00.30.40.40.50.40.80.50.41.40.50.5-0.5-0.20.00.2
Pavlov. Cond. magazine entry number0.40.52.50.0-0.7-0.2-0.4-0.8-1.2-0.2-0.4-1.6-0.6-0.70.90.30.7-0.3
Pavlov. Cond. intertrial magazine entries0.50.64.00.30.01.32.0-0.8-0.61.2-0.10.2-0.0-0.4-0.5-0.4-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.42.20.40.60.30.20.81.00.30.51.50.70.9-0.4-0.1-0.00.4
Pavlov. Cond. response bias0.50.63.30.10.80.40.60.71.20.40.51.80.70.8-0.9-0.3-0.60.3
Bone: apparent density0.81.33.91.51.31.50.50.60.91.11.22.01.51.20.60.40.60.8
Bone surface1.93.36.31.72.50.90.71.92.40.22.32.12.42.31.11.71.12.0
Bone volume2.03.36.02.12.31.2-0.01.62.00.52.32.02.42.31.61.61.81.9
Bone: connectivity density0.40.72.50.70.81.11.50.30.70.90.71.60.80.6-0.40.0-0.40.3
Bone: cortical apparent density0.10.21.10.3-0.30.2-1.0-0.3-0.50.3-0.10.3-0.0-0.10.6-0.10.2-0.1
Bone: cortical area1.42.14.61.31.5-0.2-0.31.51.5-0.81.80.31.51.62.02.21.71.9
Bone: cortical porosity0.40.54.10.80.00.92.00.10.10.80.50.40.30.1-0.20.2-0.2-0.1
Bone: cortical porosity0.50.63.11.00.60.81.80.50.60.60.90.60.70.50.10.60.30.3
Bone: cortical thickness0.30.51.5-0.4-0.9-0.20.3-1.0-1.0-0.1-0.7-1.2-0.9-0.90.0-0.2-0.5-0.6
Bone: cortical thickness4.14.87.8-2.5-2.4-1.10.5-2.3-2.3-0.4-2.6-2.7-2.8-2.8-2.1-1.9-2.1-2.3
Bone: cortical tissue density0.10.11.10.3-0.30.2-1.1-0.3-0.50.2-0.10.3-0.0-0.00.5-0.10.2-0.1
Bone: elastic displacement1.92.13.4-1.4-1.8-0.5-0.2-1.6-1.8-0.1-1.8-1.6-1.8-1.9-1.1-1.4-1.1-1.7
Bone: elastic work2.53.27.2-0.9-2.50.40.5-2.4-2.71.0-2.1-1.7-2.1-2.3-1.0-1.8-0.9-2.2
Bone: endosteal estimation3.47.312.02.52.90.2-1.02.93.1-0.93.22.13.23.12.93.13.53.2
Bone: endosteal perimeter3.47.010.42.63.00.4-1.12.83.0-0.73.21.93.23.13.03.13.13.1
Bone: final force0.20.31.20.9-0.21.11.0-0.6-0.41.00.1-0.20.0-0.20.3-0.0-0.0-0.3
Bone: final moment0.30.51.91.0-0.31.41.2-0.8-0.61.30.1-0.00.0-0.30.2-0.2-0.1-0.4
Bone: marrow area3.57.612.72.63.00.2-1.13.03.1-0.83.32.23.23.23.03.13.63.2
Bone: maximum diameter3.66.710.42.02.9-0.4-1.32.93.0-1.43.01.42.92.92.93.23.03.2
Bone: maximum force0.40.71.81.10.80.4-0.00.50.60.01.0-0.20.90.81.31.11.20.9
Bone: maximum moment0.30.61.31.10.70.70.10.30.40.30.9-0.10.80.71.20.91.10.7
Bone: minimum diameter3.66.710.62.32.7-0.1-1.32.82.9-1.23.11.12.93.03.23.33.13.1
Bone: periosteal estimation3.46.910.42.42.90.0-0.72.83.0-1.03.21.73.03.02.93.23.13.2
Bone: periosteal perimeter5.08.213.03.13.31.0-0.42.93.1-0.23.62.43.63.43.23.22.93.3
Bone: post-yield work2.43.36.20.52.2-1.3-1.12.22.3-1.91.8-0.01.62.01.92.41.72.5
Bone: stiffness0.50.81.40.50.9-0.4-0.50.81.0-0.70.9-0.60.70.91.11.21.21.2
Bone: tissue strength1.51.42.3-0.6-0.90.91.4-1.5-1.21.2-1.2-0.5-1.0-1.1-1.5-1.5-1.4-1.5
Bone: trabecular number0.30.41.10.80.80.60.60.40.60.40.81.10.80.70.40.50.40.6
Bone: trabecular spacing0.71.02.50.0-1.21.00.6-1.3-1.61.3-1.0-0.1-0.9-1.0-0.4-1.1-0.5-1.2
Bone: trabecular thickness0.81.01.70.71.2-0.1-0.81.11.2-0.51.20.11.31.21.11.11.01.3
Bone: trabecular tissue density1.31.92.81.31.40.1-1.21.41.4-0.41.61.21.71.61.61.41.41.6
Breakpoint value in progressive ratio session1.41.63.81.41.30.90.51.21.60.51.61.91.81.60.60.9-0.31.3
Distance traveled before self-admin0.40.41.6-1.3-0.1-1.10.70.20.2-1.0-0.4-0.4-0.5-0.2-1.0-0.1-0.4-0.2
Distance traveled after self-admin0.20.20.90.30.50.31.00.50.40.20.50.70.40.5-0.20.3-0.5-0.0
Delta time in closed arm before/after self-admin0.10.10.4-0.3-0.6-0.2-0.0-0.4-0.40.0-0.4-0.3-0.5-0.4-0.3-0.3-0.1-0.2
Delta time in open arm before/after self-admin0.50.51.61.00.51.20.5-0.2-0.11.00.50.90.60.40.50.1-1.2-0.1
Diff in mean of infusions in LGA sessions0.50.61.70.60.81.01.10.50.90.70.71.31.00.6-0.7-0.1-0.20.5
Extinction: sum of active levers before priming1.51.54.72.20.61.4-1.00.50.80.81.31.41.41.02.01.01.00.8
Active lever presses in extinction session 61.91.84.71.61.30.80.71.31.40.31.72.21.81.81.01.20.41.3
Delta distance traveled before/after self-admin1.31.43.92.01.11.70.70.60.61.41.41.71.41.20.90.70.50.6
Delta ambulatory time before/after self-admin0.80.92.31.50.91.30.80.50.50.91.11.21.10.90.70.60.50.5
Time in closed arm before self-admin0.10.10.3-0.10.40.30.50.10.10.2-0.00.20.20.1-0.5-0.3-0.40.0
Time in closed arm after self-admin0.30.30.7-0.6-0.50.10.2-0.4-0.60.2-0.7-0.2-0.5-0.6-0.8-0.8-0.4-0.4
Time in open arm before self-admin0.30.31.1-0.4-0.8-0.70.1-0.3-0.4-0.4-0.5-0.8-0.7-0.5-0.3-0.11.0-0.3
Time in open arm after self-admin1.41.53.31.81.40.90.40.91.10.41.71.21.61.51.41.5-0.01.0
Sum of active levers in priming session hrs 5-63.33.36.62.22.01.40.81.82.10.62.32.52.62.11.21.50.71.7
Time to tail flick, vehicle, before self-admin0.50.51.1-0.9-0.6-0.20.1-0.6-0.90.1-0.9-0.5-0.8-0.7-1.0-1.0-0.6-0.6
Time to tail flick, vehicle, after self-admin2.52.66.4-1.4-1.70.51.1-1.7-1.71.1-2.0-0.5-1.6-1.8-2.3-2.5-0.5-2.1
Time to tail flick, test, before self-admin1.81.83.7-1.6-1.3-0.9-0.7-1.2-1.3-0.5-1.7-1.9-1.6-1.5-1.2-1.2-1.9-1.0
Time to tail flick, test, after self-admin1.81.94.8-2.2-1.1-2.0-0.8-0.4-1.0-1.4-1.5-2.1-1.7-1.3-1.4-0.80.5-0.8
Delta time to tail flick, vehicle, before/after SA1.21.22.6-0.9-1.20.21.4-1.1-0.80.6-1.2-0.4-1.1-1.3-1.6-1.4-0.2-1.6
Delta time to tail flick, test, before/after SA0.30.32.9-0.5-0.2-0.7-0.30.2-0.2-0.6-0.2-0.5-0.4-0.1-0.10.11.7-0.1
Ambulatory time before self-admin0.20.20.8-0.70.1-0.40.90.30.2-0.4-0.10.3-0.10.0-0.8-0.10.3-0.1
Ambulatory time after self-admin0.40.41.60.60.60.91.10.40.40.80.51.30.60.6-0.2-0.0-0.0-0.0
Total heroin consumption2.42.94.71.61.90.4-0.11.92.1-0.22.12.12.22.21.41.61.42.0
Area under the delay curve0.30.30.60.60.60.60.70.50.50.40.60.80.70.60.10.30.10.6
Delay disc. indifference point, 0s delay0.91.03.2-0.6-0.50.71.5-0.8-0.61.1-0.90.5-0.7-0.7-1.8-1.4-0.7-1.2
Delay disc. indifference point, 16s delay1.21.23.21.11.10.1-0.51.10.8-0.51.30.31.21.21.81.60.51.6
Delay disc. indifference point, 2s delay0.60.72.30.50.01.41.5-0.5-0.41.5-0.20.90.0-0.1-0.9-0.8-0.4-0.6
Delay disc. indifference point, 24s delay0.30.30.70.60.80.40.20.60.5-0.10.80.30.70.50.60.7-0.10.7
Delay disc. indifference point, 4s delay0.20.20.8-0.40.4-0.60.80.60.9-0.60.30.10.10.4-0.50.40.10.4
Delay disc. indifference point, 8s delay0.80.82.61.30.71.61.10.40.41.20.71.51.10.80.30.20.10.5
Delay discount exponential model param0.30.30.6-0.6-0.7-0.7-0.6-0.5-0.4-0.4-0.6-0.8-0.7-0.6-0.2-0.4-0.1-0.6
Delay discount hyperbolic model param0.10.10.4-0.4-0.4-0.5-0.6-0.3-0.3-0.4-0.3-0.6-0.4-0.40.0-0.2-0.0-0.4
Fecal boli incidents, locomotor time 10.50.51.3-0.4-0.90.0-1.1-0.7-1.10.4-1.0-0.6-0.7-0.8-0.1-1.00.1-0.8
Change in fecal boli incidents, locomotor task1.41.44.9-0.90.7-2.0-1.61.21.4-2.20.5-0.60.20.50.51.10.81.0
Time >=10cm from walls, locomotor time 10.50.54.80.3-0.50.2-2.2-0.5-0.40.0-0.2-0.40.0-0.30.9-0.10.7-0.1
Bouts of movement, locomotor time 12.52.86.81.31.4-0.5-2.01.81.1-1.01.70.71.61.72.22.02.61.8
Total resting periods, locomotor time 12.22.55.71.41.2-0.3-2.31.60.8-0.81.60.61.51.62.31.82.41.6
Rest time, locomotor task time 11.01.16.4-0.10.1-1.3-2.50.80.1-1.30.1-0.70.10.31.20.81.70.6
Distance moved, locomotor task time 10.50.61.50.1-0.70.81.2-1.0-1.00.9-0.4-0.3-0.7-0.8-0.5-0.6-0.6-0.9
Vertical activity count, locomotor time 11.01.11.8-1.0-1.1-0.21.2-1.1-1.00.1-1.1-0.8-1.3-1.2-1.3-1.0-0.7-1.2
Time >=10cm from walls, locomotor time 21.71.84.2-0.3-1.51.2-0.0-2.0-1.61.4-1.4-0.4-1.2-1.7-1.0-1.7-0.9-1.9
Bouts of movement, locomotor time 21.41.53.80.41.7-0.11.01.72.0-0.61.31.31.51.50.21.1-0.31.4
Total resting periods, locomotor time 21.61.74.10.41.8-0.40.61.92.0-0.91.41.11.51.60.51.30.01.6
Rest time, locomotor task time 20.91.03.9-1.4-0.8-1.5-2.0-0.0-0.7-1.2-1.1-1.4-0.9-0.7-0.2-0.60.3-0.1
Distance moved, locomotor task time 20.60.72.61.1-0.61.50.9-1.1-1.11.6-0.00.3-0.3-0.50.1-0.40.2-1.0
Vertical activity count, locomotor time 20.40.41.0-0.3-0.9-0.20.6-0.8-0.70.1-0.5-0.5-0.9-0.7-0.6-0.40.1-1.0
Weight adjusted by age5.25.89.92.23.11.32.42.62.80.43.03.13.03.11.02.11.42.5
Seeking ratio, delayed vs. immediate footshock0.20.20.9-0.2-0.5-0.6-0.0-0.1-0.7-0.4-0.3-0.9-0.5-0.30.40.30.1-0.5
Locomotion in novel chamber0.40.52.1-1.00.3-1.5-0.30.51.0-1.20.0-0.2-0.10.2-0.60.1-0.60.5
Locomotion in novel chamber post-restriction0.40.51.6-0.1-1.00.3-0.5-1.0-1.30.5-0.8-0.8-0.7-1.00.2-0.70.3-0.5
Progressive ratio0.30.31.40.5-0.51.20.3-0.7-0.51.1-0.30.2-0.1-0.40.1-0.5-0.5-0.5
Food seeking constrained by brief footshock0.60.72.1-0.8-0.50.11.3-0.7-0.50.4-0.9-0.5-0.9-0.8-1.4-1.0-0.8-0.8
Seeking ratio, punishment vs. effort0.10.20.6-0.60.2-0.80.40.30.2-0.5-0.1-0.2-0.20.1-0.60.10.40.1
Run reversals in cocaine runway, females1.01.03.51.60.21.3-0.70.2-0.11.00.71.00.90.61.40.31.90.6
Run reversals in cocaine runway, males0.50.42.30.30.50.60.90.30.90.60.41.50.50.6-0.6-0.2-0.60.1
Latency to leave start box in cocaine runway0.40.41.3-0.70.6-1.00.20.81.2-1.00.30.20.30.4-0.60.40.10.4
Latency to leave start box in cocaine runway, F0.60.61.60.21.2-0.20.31.11.3-0.50.90.50.90.90.10.80.90.7
Latency to leave start box in cocaine runway, M0.80.84.2-1.4-0.2-2.0-1.00.40.5-1.8-0.3-0.8-0.4-0.0-0.20.30.10.5
Cd content in liver0.60.61.8-0.1-1.20.30.0-1.1-1.30.7-0.9-0.6-0.9-1.0-0.2-0.8-0.2-1.0
Co content in liver1.61.82.81.61.50.4-0.61.51.3-0.11.71.11.71.51.51.51.51.5
Cu content in liver1.41.74.2-0.3-0.21.52.1-1.1-0.71.7-0.70.8-0.4-0.8-1.9-1.6-2.1-1.3
Fe content in liver0.40.51.3-0.31.1-0.70.10.81.1-1.00.6-0.10.60.6-0.00.80.80.8
K content in liver0.50.51.50.61.00.40.20.81.10.20.81.20.91.00.00.3-0.30.6
Mg content in liver1.51.55.91.21.51.41.30.81.31.11.32.41.51.4-0.20.3-0.20.6
Mn content in liver0.10.10.70.30.10.60.8-0.10.00.50.20.80.10.2-0.2-0.10.0-0.2
Na content in liver0.40.41.10.50.60.61.00.70.70.40.61.10.70.7-0.30.1-0.90.3
Rb content in liver1.11.43.61.80.91.91.40.10.31.61.11.91.20.80.40.41.00.3
Se content in liver0.10.10.5-0.70.1-0.20.2-0.0-0.1-0.2-0.4-0.1-0.3-0.2-0.7-0.4-0.6-0.2
Sr content in liver0.60.51.7-0.2-0.9-0.2-1.1-0.8-1.1-0.0-0.8-1.3-0.8-0.90.3-0.4-0.3-0.5
Zn content in liver1.31.44.30.90.82.12.0-0.10.31.90.41.60.90.4-1.0-0.8-1.3-0.3