Hub : Genes

Acer3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000019987 0.23 0.14 6.5e-04 0.01 0 0.02 0.02 1.2e-02 7.5e-02 1.6e-03 4.7e-03
2 Adipose alternative polyA ENSRNOT00000100763 0.37 0.15 6.7e-05 0.02 0.03 0.03 0.01 4.6e-03 3.2e-04 1.0e-04 9.7e-03
3 Adipose alternative polyA ENSRNOT00000019987 0.06 0.04 7.6e-05 0.02 0.03 0.03 0.03 3.5e-03 1.8e-04 2.5e-04 1.7e-04
4 Adipose alternative polyA ENSRNOT00000102980 0.06 0.05 3.9e-05 0.02 0.04 0.04 0.04 6.2e-03 9.1e-05 7.6e-05 8.9e-05
5 Adipose gene expression ENSRNOG00000036866 0.73 0.09 0.0e+00 0.34 0.5 0.5 0.5 6.1e-39 5.1e-63 3.6e-64 6.3e-64
6 Adipose isoform ratio ENSRNOT00000019987 0.1 0.1 3.9e-03 0.01 0.01 0.02 0.01 1.0e-02 6.3e-02 5.8e-03 1.3e-02
7 Adipose mRNA stability ENSRNOG00000036866 0.58 0.1 0.0e+00 0.16 0.23 0.22 0.21 1.1e-17 1.5e-25 3.5e-24 1.6e-22
8 Liver gene expression ENSRNOG00000036866 0.24 0.12 1.3e-04 0.03 0.03 0.03 0.03 4.6e-04 4.2e-04 3.0e-04 8.2e-04
9 OFC alternative polyA ENSRNOT00000019987 0.14 0.09 5.0e-03 0.08 0.05 0.01 0.06 5.6e-03 2.7e-02 1.4e-01 1.5e-02
10 OFC alternative polyA ENSRNOT00000102980 0.13 0.09 7.4e-03 0.08 0.04 0.01 0.06 7.0e-03 3.3e-02 1.7e-01 1.9e-02
11 OFC alternative TSS ENSRNOT00000019987 0.18 0.13 8.2e-03 0.01 0.08 0.02 0.02 1.9e-01 7.4e-03 9.5e-02 1.2e-01
12 OFC alternative TSS ENSRNOT00000102980 0.17 0.12 8.9e-03 0.01 0.07 0.01 0.01 1.9e-01 8.4e-03 1.5e-01 1.4e-01
13 OFC alternative TSS ENSRNOT00000019987 0.19 0.1 1.8e-03 0.12 0.1 0.07 0.09 8.6e-04 2.5e-03 9.0e-03 3.1e-03
14 OFC alternative TSS ENSRNOT00000102980 0.19 0.11 1.8e-03 0.12 0.1 0.07 0.09 7.6e-04 2.6e-03 9.1e-03 3.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.72.23.9-1.80.8-1.31.20.90.00.6-1.8-1.91.92.0-1.91.4-1.4
BMI without tail3.47.019.6-1.6-0.0-1.61.50.80.02.0-1.8-2.52.54.4-4.43.9-3.9
Body weight1.35.615.9-1.70.2-1.31.20.50.01.2-1.9-2.52.54.0-4.03.4-3.4
Epididymis fat weight2.15.08.6-2.3-0.1-2.22.11.60.01.9-2.8-2.72.72.9-2.92.2-2.2
Glucose0.10.10.30.5-0.10.5-0.5-0.50.0-0.20.10.3-0.3-0.30.3-0.00.0
Heart weight0.40.61.50.9-0.01.2-1.1-1.20.0-1.20.40.9-0.90.0-0.00.4-0.4
Left kidney weight0.72.06.30.6-0.00.6-0.7-1.10.00.5-0.4-0.30.32.5-2.52.4-2.4
Right kidney weight0.51.34.40.50.10.5-0.5-0.90.00.6-0.3-0.20.22.1-2.11.9-1.9
Tail length2.37.123.80.4-0.50.2-0.4-1.20.01.4-0.7-0.90.94.8-4.84.9-4.9
Length with tail1.24.314.4-0.2-0.1-0.20.1-0.50.01.2-0.6-1.31.33.8-3.83.6-3.6
Length without tail0.10.30.9-0.50.5-0.20.20.40.0-0.20.2-0.40.4-0.70.7-1.01.0
Liver weight, left0.71.12.1-1.21.1-0.90.90.60.01.0-1.1-1.01.01.4-1.41.2-1.2
Liver weight, right2.64.37.1-2.40.9-2.22.11.80.02.1-1.7-2.72.72.6-2.61.8-1.8
Parametrial fat weight0.91.73.3-1.50.7-1.31.21.00.00.6-1.2-1.51.51.8-1.81.3-1.3
Retroperitoneal fat weight5.819.132.7-5.00.9-4.74.53.80.04.3-5.1-5.75.74.9-4.83.7-3.7
Intraocular pressure0.60.92.10.90.01.0-0.9-0.90.0-1.40.21.1-1.1-1.51.4-0.30.3
Extensor digitorum longus weight0.52.14.7-1.61.1-1.41.31.00.00.9-2.2-1.51.51.6-1.61.8-1.8
Soleus weight1.02.95.4-1.3-0.7-1.31.20.90.01.6-1.7-1.91.92.3-2.32.3-2.3
Tibialis anterior weight0.10.41.3-0.31.1-0.20.1-0.10.0-0.1-0.2-0.20.21.1-1.11.0-1.0
Tibia length0.92.65.92.1-0.32.0-2.0-2.00.0-2.41.92.0-2.0-0.80.8-0.50.5
Number of licking bursts2.83.47.2-2.70.7-2.72.72.70.01.9-1.9-2.32.30.3-0.2-0.10.1
Food consumed during 24 hour testing period3.34.09.83.1-0.92.7-2.6-2.50.0-0.82.72.6-2.6-0.90.9-0.80.8
Times rat made contact with spout0.50.62.6-0.4-0.0-0.60.60.50.01.6-0.3-0.80.81.0-0.90.6-0.6
Mean time between licks in bursts2.13.06.32.1-0.72.1-2.2-2.50.0-0.61.21.1-1.12.0-2.02.1-2.1
Mean num. licks in bursts2.02.45.62.4-0.42.4-2.3-2.40.0-1.31.61.9-1.90.1-0.10.3-0.3
Std. dev. time between licks in bursts1.01.23.60.7-0.20.6-0.6-0.90.00.60.6-0.00.01.9-1.91.8-1.8
Water consumed over 24 hours0.50.62.5-0.7-0.0-1.01.11.20.01.6-0.5-0.80.8-0.20.2-0.50.5
Indifference point 0 sec2.94.710.02.61.73.0-3.1-3.20.0-2.82.52.4-2.40.7-0.80.8-0.8
Indifference point AUC0.10.10.4-0.10.3-0.10.1-0.10.0-0.3-0.4-0.30.30.5-0.50.6-0.6
Indifference point function ln k1.31.93.31.7-0.31.7-1.7-1.60.0-1.51.71.8-1.8-0.90.9-0.80.8
Indifference point function log k1.31.93.31.7-0.31.7-1.7-1.60.0-1.51.71.8-1.8-0.90.9-0.80.8
Delay discounting total patch changes 0 sec2.54.08.32.41.62.7-2.8-2.90.0-2.72.32.2-2.20.6-0.60.7-0.7
Delay discounting total patch changes 12 sec0.60.81.90.60.50.7-0.8-1.00.0-0.80.30.2-0.21.3-1.31.4-1.4
Delay discounting total patch changes 18 sec0.91.22.31.30.61.2-1.3-1.50.0-0.70.70.8-0.81.1-1.21.5-1.5
Delay discounting total patch changes 24 sec0.40.51.30.61.20.7-0.7-0.90.0-0.30.50.3-0.30.8-0.90.9-0.9
Delay discounting total patch changes 6 sec0.81.24.50.91.01.2-1.2-1.30.0-2.11.71.2-1.20.1-0.10.0-0.0
Delay discounting time to switch 0 sec2.13.27.8-2.3-0.9-2.62.62.80.02.3-1.4-1.91.9-0.70.7-1.11.1
Delay discounting water rate 0 sec1.93.06.82.20.42.5-2.5-2.60.0-2.21.52.1-2.10.3-0.30.8-0.8
Delay discounting water rate 12 sec1.72.55.32.3-0.12.3-2.3-2.30.0-1.51.92.1-2.1-0.10.10.3-0.3
Delay discounting water rate 18 sec0.40.51.31.00.21.1-1.1-1.10.0-0.40.50.8-0.80.3-0.30.5-0.5
Delay discounting water rate 24 sec1.01.42.71.6-0.41.5-1.5-1.30.0-1.10.91.6-1.6-1.11.1-0.60.6
Delay discounting water rate 6 sec0.71.02.31.30.61.2-1.2-1.10.0-1.11.01.5-1.5-0.80.7-0.30.3
Locomotor activity0.81.33.31.8-0.81.5-1.4-1.50.00.01.71.0-1.00.9-0.90.8-0.8
Locomotor testing distance1.21.93.81.7-0.11.6-1.7-2.00.0-0.51.11.0-1.01.8-1.81.6-1.6
Locomotor testing rearing1.01.66.10.4-0.00.4-0.5-0.80.00.40.4-0.50.52.5-2.52.0-2.0
Light reinforcement 11.12.04.6-2.11.2-2.12.02.00.01.2-1.2-1.71.70.5-0.4-0.00.0
Light reinforcement 20.20.31.1-0.11.00.1-0.1-0.00.0-0.70.60.4-0.4-0.30.3-0.80.8
Reaction time number correct0.71.03.20.80.00.7-0.7-0.40.0-0.61.81.1-1.1-1.11.1-1.51.5
Reaction time mean minus median0.81.01.81.0-0.11.1-1.1-1.30.0-0.81.00.5-0.51.2-1.21.3-1.3
Reaction time mean minus median AUC1.01.32.81.50.21.5-1.5-1.60.0-1.31.71.1-1.10.7-0.70.7-0.7
Reaction time num false alarms2.12.85.6-2.40.5-2.42.32.30.01.4-2.2-2.32.30.5-0.50.1-0.1
Reaction time num false alarms AUC1.01.53.0-1.60.2-1.71.71.70.01.1-1.6-1.61.6-0.10.1-0.40.4
Reaction time trials correct on left0.71.03.20.80.00.7-0.7-0.40.0-0.61.81.1-1.1-1.11.1-1.51.5
Reaction time trials on left0.81.13.30.80.10.8-0.7-0.40.0-0.71.81.1-1.1-1.11.1-1.51.5
Reaction time mean0.20.30.5-0.60.7-0.50.40.30.00.3-0.2-0.70.70.7-0.70.6-0.6
Reaction time mean AUC0.20.30.6-0.70.7-0.60.60.50.00.4-0.3-0.80.80.4-0.30.2-0.2
Median of all reaction times0.30.40.7-0.90.9-0.80.80.70.00.5-0.5-0.80.80.2-0.20.0-0.0
Reaction time omissions0.10.10.2-0.50.3-0.40.40.20.0-0.1-0.3-0.40.40.5-0.50.4-0.4
Reaction time false alarm rate1.62.36.0-2.10.5-2.12.01.90.01.2-2.4-2.12.10.4-0.40.3-0.3
Reaction time premature initiation rate1.62.27.7-0.10.20.2-0.3-0.70.0-0.1-0.6-0.50.52.8-2.82.6-2.6
Reaction time premature initiations0.71.03.40.40.20.6-0.7-1.00.0-0.50.50.2-0.21.8-1.81.5-1.5
Std. dev. reaction times0.70.93.20.20.10.3-0.3-0.60.0-0.0-0.1-0.30.31.7-1.71.8-1.8
Reaction time trials completed0.81.13.30.80.10.8-0.7-0.40.0-0.71.81.1-1.1-1.11.1-1.51.5
Reaction time trials AUC0.60.93.00.70.00.8-0.7-0.40.0-0.61.71.0-1.0-0.80.9-1.31.3
Social response proportion0.40.41.2-0.80.2-0.70.70.70.01.10.4-0.80.80.6-0.60.1-0.1
Social responses1.31.62.4-1.50.8-1.51.41.30.01.5-0.9-1.51.51.4-1.41.1-1.1
Social time1.41.84.2-1.90.6-1.81.92.10.01.3-0.4-1.51.5-0.60.6-1.31.3
Conditioned locomotion0.20.20.40.4-0.50.2-0.2-0.10.0-0.10.60.4-0.4-0.70.7-0.50.5
Cocaine response after cond. corrected0.91.14.1-1.40.2-1.31.21.20.00.7-2.0-1.31.3-0.00.00.0-0.0
Cocaine response after cond. not corrected0.20.31.1-0.60.5-0.50.40.40.0-0.1-1.0-0.50.5-0.50.5-0.60.6
Cocaine response before conditioning1.41.84.81.60.41.5-1.5-1.30.0-1.32.21.6-1.6-0.80.8-1.21.2
Saline control response1.01.33.21.5-0.21.6-1.6-1.80.0-0.81.21.0-1.01.1-1.10.9-0.9
Condit. Reinf. active minus inactive responses2.43.06.81.71.52.2-2.3-2.60.0-2.60.81.4-1.41.4-1.41.6-1.6
Condit. Reinf. active-inactive response ratio0.30.31.10.31.00.6-0.7-0.80.0-1.1-0.30.3-0.30.3-0.30.4-0.4
Condit. Reinf. active responses3.75.111.52.31.42.8-3.0-3.40.0-2.91.01.8-1.82.1-2.12.4-2.4
Condit. Reinf. inactive responses3.03.88.22.4-0.32.4-2.5-2.90.0-1.51.71.5-1.52.0-2.02.1-2.1
Condit. Reinf. lever presses10.013.832.05.00.35.3-5.4-5.70.0-5.13.34.4-4.40.7-0.71.5-1.5
Condit. Reinf. lever reinforcers received4.05.713.32.61.33.1-3.2-3.60.0-3.21.22.0-2.02.0-2.02.3-2.3
Pavlov. Cond. lever latency10.013.831.2-5.0-0.4-5.35.45.60.05.2-3.0-4.64.6-0.20.3-1.01.0
Pavlov. Cond. magazine entry latency3.23.711.22.40.42.5-2.6-2.60.0-3.41.32.5-2.5-0.80.7-0.20.2
Pavlov. Cond. change in total contacts6.99.621.84.10.64.4-4.5-4.70.0-4.62.63.7-3.70.2-0.30.6-0.6
Pavlov. Cond. index score7.810.222.74.20.44.5-4.6-4.80.0-4.72.53.9-3.9-0.0-0.10.7-0.7
Pavlov. Cond. latency score7.49.421.64.10.54.3-4.4-4.50.0-4.62.43.8-3.8-0.20.20.4-0.4
Pavlov. Cond. lever contacts10.514.633.25.10.35.4-5.5-5.80.0-5.33.24.6-4.60.4-0.51.2-1.2
Pavlov. Cond. magazine entry number3.94.812.7-2.9-0.6-3.03.13.20.03.6-1.0-2.72.70.8-0.7-0.00.0
Pavlov. Cond. intertrial magazine entries1.11.54.7-0.6-0.2-0.50.50.20.01.4-0.1-0.90.92.2-2.11.9-1.9
Pavlov. Cond. lever-magazine prob. diff.7.29.321.04.00.54.3-4.4-4.60.0-4.62.43.8-3.80.1-0.10.7-0.7
Pavlov. Cond. response bias10.314.232.45.10.45.3-5.5-5.70.0-5.33.04.6-4.60.3-0.31.2-1.2
Conditioned reinforcement - actives2.22.23.81.80.12.0-1.9-1.70.0-1.71.61.9-1.9-1.21.1-0.80.8
Conditioned reinforcement - inactives0.10.10.3-0.20.5-0.10.20.30.00.40.5-0.00.0-0.50.5-0.50.5
Conditioned locomotion1.92.23.91.90.22.0-1.9-1.70.0-1.71.61.9-1.9-1.21.1-0.90.9
Intermittent access intake day 1-15 change2.12.13.81.80.11.9-1.9-1.70.0-1.81.61.9-1.9-1.11.1-0.60.6
Intermittent access intake escalation2.52.54.42.0-0.12.1-2.1-1.90.0-1.91.62.1-2.1-1.01.0-0.60.6
Intermittent access intake escalation 20.50.51.00.90.31.0-1.0-0.90.0-0.90.90.9-0.9-0.20.2-0.10.1
Intermitt. access day 1 inactive lever presses0.50.53.1-0.71.8-0.70.70.80.01.00.4-0.70.7-0.00.0-0.20.2
Intermitt. access day 15 inactive lever presses0.40.43.8-0.01.90.0-0.00.10.00.10.60.2-0.2-0.60.6-0.60.6
Intermitt. access escalation Index0.00.00.10.0-0.4-0.00.00.00.0-0.10.40.1-0.10.00.0-0.10.1
Intermittent access day 1 total infusions0.20.30.70.7-0.10.8-0.8-0.80.0-0.40.20.5-0.50.2-0.30.6-0.6
Intermittent access day 15 total infusions2.02.24.32.0-0.12.1-2.0-1.90.0-1.71.32.0-2.0-1.00.9-0.40.4
Intermittent access terminal intake (last 3 days)0.91.02.21.30.51.5-1.4-1.40.0-1.31.01.3-1.3-0.40.30.2-0.2
Intermittent access total infusions0.30.40.90.90.21.0-0.9-0.90.0-0.70.30.8-0.8-0.10.10.2-0.2
Intermittent access day 1 locomotion0.10.10.30.20.40.3-0.2-0.10.0-0.20.40.3-0.3-0.60.6-0.50.5
Intermittent access day 15 total locomotion1.21.32.61.50.71.6-1.6-1.60.0-1.21.31.5-1.5-0.40.3-0.00.0
Intermittent access total locomotion0.30.30.80.80.40.9-0.9-0.90.0-0.60.60.6-0.60.1-0.10.3-0.3
Intermittent access standard deviation0.00.10.10.20.30.4-0.3-0.30.0-0.00.00.1-0.10.3-0.30.1-0.1
Cocaine induced anxiety1.31.53.4-1.7-0.0-1.71.81.80.01.5-1.2-1.61.6-0.20.2-0.60.6
Post-drug Anxiety0.30.30.6-0.7-0.1-0.70.70.80.00.7-0.5-0.60.6-0.30.3-0.40.4
Baseline Anxiety1.61.73.61.80.71.9-1.9-1.90.0-1.41.11.8-1.8-0.30.30.2-0.2
Lifetime Intake0.50.61.41.10.11.2-1.2-1.10.0-0.80.41.0-1.0-0.20.20.1-0.1
Incentive Sensitization - Responses1.31.32.91.40.81.5-1.6-1.70.0-1.10.31.0-1.00.8-0.81.2-1.2
Incentive Sensitization - Breakpoint1.21.23.01.50.81.5-1.6-1.70.0-1.10.31.1-1.10.7-0.71.0-1.0
Progressive ratio test 1 active lever presses0.10.10.2-0.30.1-0.30.30.40.00.10.2-0.10.1-0.50.5-0.30.3
Progressive ratio test 1 breakpoint0.10.10.2-0.30.1-0.30.30.40.00.10.2-0.20.2-0.40.4-0.30.3
Progressive ratio test 1 inactive lever presses0.00.00.20.10.40.2-0.2-0.20.0-0.10.30.1-0.10.0-0.00.1-0.1
Progressive ratio test 2 active lever presses0.70.81.81.10.91.2-1.2-1.30.0-0.80.30.8-0.80.5-0.50.9-0.9
Progressive ratio test 2 breakpoint0.60.71.51.01.11.1-1.1-1.20.0-0.80.40.6-0.60.5-0.60.9-0.9
Progressive ratio test 2 inactive lever presses0.30.41.00.71.00.8-0.8-0.90.0-0.40.50.5-0.50.2-0.30.6-0.6
Total sessions with >9 infusions1.51.63.11.7-0.51.8-1.7-1.70.0-1.71.41.7-1.7-0.40.4-0.20.2
Short access day 1 total inactive lever presses0.10.10.30.00.20.1-0.1-0.00.00.60.10.1-0.1-0.30.3-0.30.3
Short access day 10 total inactive lever presses0.10.20.6-0.30.8-0.30.30.40.00.40.8-0.20.20.00.0-0.40.4
Short access day 1 total infusions1.41.53.31.7-0.51.8-1.8-1.80.0-1.21.01.5-1.50.2-0.20.4-0.4
Short access day 10 total infusions0.20.20.50.60.20.7-0.7-0.70.0-0.5-0.20.4-0.40.3-0.30.5-0.5
Short access total infusions0.20.30.60.7-0.20.8-0.8-0.80.0-0.60.10.7-0.70.1-0.10.2-0.2
Short access day 1 locomotion2.83.05.12.00.52.1-2.1-1.80.0-2.11.82.2-2.2-1.51.5-1.11.1
Short access day 10 total locomotion0.10.20.30.40.50.5-0.5-0.50.0-0.50.60.2-0.20.3-0.30.3-0.3
Short access total locomotion0.30.30.70.40.90.5-0.5-0.30.0-0.60.80.6-0.6-0.30.4-0.50.5
Compulsive drug intake0.00.00.10.10.20.1-0.1-0.10.0-0.2-0.10.1-0.1-0.10.1-0.20.2
One hour access (0.3 mA shock)0.91.02.31.31.31.4-1.4-1.50.0-0.90.51.0-1.00.4-0.40.7-0.7
One hour access (shock baseline)0.91.02.21.41.01.5-1.5-1.40.0-0.91.11.1-1.10.0-0.10.3-0.3
Number of responses in last shaping day0.70.71.6-0.60.3-0.60.50.30.00.6-0.6-0.90.91.3-1.31.2-1.2
Context. condit. distance diff. score0.91.24.81.10.51.3-1.3-1.30.0-2.20.81.3-1.3-0.70.70.1-0.1
Locomotion velocity, session 10.70.72.20.8-0.50.5-0.4-0.20.00.40.30.9-0.9-1.51.5-1.11.1
Locomotion distance, session 10.70.91.41.1-0.11.2-1.2-1.00.0-1.10.81.1-1.1-0.80.8-1.01.0
Locomotion velocity, session 20.30.41.21.10.30.9-0.9-0.80.00.70.40.7-0.7-0.20.2-0.10.1
Locomotion distance, session 20.30.40.80.90.20.9-0.9-0.80.00.00.80.8-0.80.1-0.1-0.10.1
Locomotion velocity, session 30.20.20.60.8-0.20.7-0.7-0.60.0-0.20.50.7-0.7-0.40.4-0.10.1
Locomotion distance, session 30.80.91.51.10.01.0-1.0-0.90.0-1.10.21.2-1.2-1.21.1-0.70.7
Stereotopy head waving bouts, day 30.30.41.5-0.2-0.8-0.30.40.40.01.20.7-0.60.60.8-0.70.3-0.3
Stereotopy head waving duration, day 30.50.52.71.0-0.50.9-0.9-0.80.0-0.21.60.8-0.8-0.00.1-0.00.0
Locomotion velocity, session 70.30.30.5-0.7-0.7-0.70.70.70.00.4-0.7-0.40.4-0.50.4-0.30.3
Locomotion distance, session 70.20.31.5-0.80.1-0.50.50.40.00.0-1.2-0.70.70.2-0.20.5-0.5
Stereotopy head waving bouts, day 71.61.84.82.0-0.51.7-1.7-1.60.0-1.02.21.7-1.7-0.70.7-0.70.7
Stereotopy head waving duration, day 71.72.14.92.2-0.62.0-2.0-2.00.0-1.02.21.7-1.7-0.20.2-0.10.1
Locomotion velocity, session 81.21.42.81.5-0.31.6-1.6-1.50.0-1.70.41.5-1.5-1.21.1-0.00.0
Locomotion distance, session 81.01.42.91.50.31.7-1.7-1.60.0-1.61.41.5-1.5-0.60.5-0.10.1
Degree of sensitization distance1.51.53.1-1.30.3-0.90.90.60.00.7-0.8-1.51.51.8-1.81.6-1.6
Degree of sensitization stereotypy3.53.87.82.8-0.12.5-2.5-2.40.0-2.12.32.5-2.5-1.21.2-1.11.1
Condit. Reinf. active minus inactive responses1.01.13.0-0.80.4-0.60.50.30.00.3-1.0-1.01.01.6-1.61.7-1.7
Condit. Reinf. active-inactive response ratio1.01.03.8-0.50.5-0.20.2-0.10.0-0.3-0.5-0.60.61.6-1.61.9-1.9
Condit. Reinf. active responses0.60.81.4-0.80.7-0.70.70.50.00.7-0.8-1.01.01.1-1.11.2-1.2
Condit. Reinf. inactive responses0.10.10.6-0.20.6-0.40.40.40.00.8-0.3-0.30.3-0.10.1-0.30.3
Incentive salience index mean0.70.82.1-0.6-0.2-0.50.50.20.00.6-1.2-0.90.91.2-1.21.4-1.4
Condit. Reinf. lever presses0.10.10.80.2-0.90.00.0-0.00.00.7-0.6-0.20.20.0-0.00.3-0.3
Time in familiar zone, hab. session 10.20.21.4-0.41.2-0.40.40.40.00.4-0.7-0.20.2-0.10.10.1-0.1
Time in novel zone, hab. session 10.30.30.6-0.5-0.7-0.50.40.30.00.2-0.4-0.70.70.8-0.80.6-0.6
Total zone transitions, hab. session 10.50.71.50.80.10.7-0.7-0.50.0-1.21.11.0-1.0-0.90.9-0.90.9
Total locomotion distance, hab. session 11.62.34.4-1.80.6-1.71.61.50.01.4-0.8-2.12.12.0-1.91.1-1.1
Locomotion velocity, hab. session 11.11.63.2-1.40.4-1.31.31.10.01.0-0.4-1.81.81.8-1.71.0-1.0
Time in familiar zone, hab. session 20.40.51.60.7-0.00.6-0.6-0.80.0-0.30.40.3-0.30.6-0.71.3-1.3
Time in novel zone, hab. session 20.20.21.0-0.30.5-0.20.10.20.0-0.0-0.50.0-0.0-0.40.4-1.01.0
Total zone transitions, hab. session 21.31.75.11.20.41.4-1.5-1.30.0-2.31.71.5-1.5-0.80.8-1.11.1
Total locomotion distance, hab. session 21.01.33.2-1.40.9-1.11.00.80.00.4-0.4-1.51.51.8-1.70.9-0.9
Locomotion velocity, hab. session 21.11.53.7-1.50.8-1.21.10.90.00.6-0.4-1.61.61.9-1.91.0-1.0
Novel to familiar place preference ratio0.20.20.60.30.30.4-0.5-0.40.0-0.80.30.4-0.4-0.10.1-0.40.4
Novelty place preference0.10.10.20.30.20.4-0.4-0.40.0-0.50.20.3-0.3-0.10.1-0.40.4
Time in novel zone, NPP test0.20.20.40.40.20.5-0.6-0.50.0-0.70.20.5-0.5-0.10.1-0.30.3
Total zone transitions, NPP test0.50.71.50.6-0.20.7-0.7-0.50.0-1.20.60.8-0.8-1.21.2-1.11.1
Total locomotion distance, NPP test1.31.83.8-1.90.9-1.71.61.50.01.0-1.1-1.91.91.3-1.20.5-0.5
Locomotion velocity, NPP test1.62.24.7-2.10.9-1.91.81.80.01.2-1.2-2.22.21.3-1.20.3-0.3
Pavlov. Cond. lever latency0.40.51.4-1.10.5-1.11.11.20.00.1-0.5-0.60.6-0.20.2-0.50.5
Pavlov. Cond. magazine entry latency0.91.12.41.00.31.3-1.4-1.60.0-1.30.50.8-0.81.0-1.01.3-1.3
Pavlov. Cond. change in total contacts0.20.20.70.60.50.8-0.8-0.90.0-0.5-0.10.4-0.40.1-0.20.1-0.1
Pavlov. Cond. index score0.81.02.51.3-0.41.3-1.4-1.60.0-0.40.30.6-0.60.9-1.01.3-1.3
Pavlov. Cond. latency score0.81.02.51.2-0.41.4-1.4-1.60.0-0.60.40.7-0.70.9-0.91.2-1.2
Pavlov. Cond. lever contacts0.30.40.80.8-0.90.8-0.8-0.90.00.5-0.10.2-0.20.5-0.60.8-0.8
Pavlov. Cond. magazine entry number1.01.33.1-1.4-0.2-1.51.61.80.01.3-0.6-1.01.0-0.80.8-1.21.2
Pavlov. Cond. intertrial magazine entries0.81.03.4-1.10.1-1.31.31.40.01.8-0.8-1.21.2-0.10.1-0.60.6
Pavlov. Cond. lever-magazine prob. diff.0.60.81.91.1-0.41.2-1.2-1.40.0-0.30.20.6-0.60.8-0.81.1-1.1
Pavlov. Cond. response bias0.30.30.80.7-0.60.6-0.6-0.80.00.30.00.1-0.10.7-0.70.9-0.9
Bone: apparent density0.10.10.3-0.4-0.1-0.50.50.50.00.2-0.4-0.00.0-0.20.20.4-0.4
Bone surface0.40.71.41.0-0.11.0-1.0-1.20.0-1.1-0.11.0-1.00.4-0.41.1-1.1
Bone volume0.30.52.10.4-0.10.4-0.4-0.60.0-0.3-0.50.3-0.30.7-0.71.4-1.4
Bone: connectivity density0.20.30.70.3-0.40.3-0.2-0.20.0-0.60.20.8-0.8-0.80.8-0.20.2
Bone: cortical apparent density0.50.71.7-1.00.1-1.01.11.00.01.3-0.9-1.11.10.2-0.20.4-0.4
Bone: cortical area0.60.92.4-0.41.4-0.10.0-0.20.0-0.9-1.2-0.40.41.3-1.41.6-1.6
Bone: cortical porosity1.61.74.21.8-1.01.7-1.7-1.50.0-1.22.01.4-1.4-0.60.6-0.90.9
Bone: cortical porosity1.41.53.81.6-1.01.5-1.5-1.30.0-0.72.01.3-1.3-0.70.7-1.01.0
Bone: cortical thickness0.40.71.6-1.21.3-1.00.90.90.0-0.1-1.1-1.01.00.4-0.40.3-0.3
Bone: cortical thickness0.20.21.3-0.20.60.2-0.3-0.20.0-1.1-0.6-0.10.1-0.30.3-0.40.4
Bone: cortical tissue density0.50.61.8-0.9-0.1-1.01.01.00.01.4-0.8-1.11.10.2-0.10.3-0.3
Bone: elastic displacement0.80.92.4-1.40.0-1.41.41.50.00.6-1.1-0.90.9-0.70.7-0.50.5
Bone: elastic work1.01.42.7-1.2-0.5-1.41.41.60.00.6-1.4-0.50.5-1.61.6-1.21.2
Bone: endosteal estimation0.61.33.90.8-0.70.8-0.8-1.10.0-0.2-0.50.2-0.21.7-1.72.0-2.0
Bone: endosteal perimeter0.81.73.41.5-0.31.5-1.6-1.90.0-0.8-0.01.0-1.01.3-1.31.8-1.8
Bone: final force0.10.21.6-0.40.4-0.10.10.00.0-1.2-0.5-0.00.0-0.20.20.2-0.2
Bone: final moment0.10.11.4-0.20.30.1-0.1-0.20.0-1.2-0.30.1-0.1-0.00.00.3-0.3
Bone: marrow area0.51.13.70.7-0.70.6-0.7-1.00.0-0.2-0.50.1-0.11.6-1.71.9-1.9
Bone: maximum diameter0.81.52.91.10.81.2-1.4-1.60.0-1.7-0.30.9-0.91.3-1.41.7-1.7
Bone: maximum force0.10.22.0-0.00.10.2-0.2-0.20.0-1.4-0.50.3-0.3-0.40.40.0-0.0
Bone: maximum moment0.10.21.70.20.00.4-0.4-0.40.0-1.3-0.30.5-0.5-0.30.20.1-0.1
Bone: minimum diameter1.01.95.8-0.60.6-0.60.50.10.00.6-1.6-0.90.92.2-2.22.4-2.4
Bone: periosteal estimation0.61.34.30.40.30.6-0.7-1.00.0-0.8-1.00.1-0.11.7-1.72.1-2.1
Bone: periosteal perimeter0.81.33.31.1-0.01.1-1.2-1.40.0-0.70.00.7-0.71.3-1.41.8-1.8
Bone: post-yield work0.20.30.80.6-0.30.7-0.7-0.70.0-0.80.90.8-0.8-0.10.10.0-0.0
Bone: stiffness0.10.21.1-0.60.7-0.30.30.30.0-1.1-0.7-0.40.4-0.20.2-0.00.0
Bone: tissue strength1.00.93.1-0.10.0-0.10.10.40.0-1.01.10.4-0.4-1.41.5-1.71.7
Bone: trabecular number0.60.92.5-1.3-0.6-1.41.51.60.00.7-1.0-0.70.7-0.70.7-0.30.3
Bone: trabecular spacing1.01.32.91.70.41.7-1.7-1.70.0-0.91.51.4-1.4-0.10.1-0.20.2
Bone: trabecular thickness0.70.92.0-1.10.3-1.01.00.80.00.8-1.4-1.01.00.8-0.81.1-1.1
Bone: trabecular tissue density0.81.22.3-1.30.6-1.21.11.00.01.0-0.9-1.51.51.4-1.30.7-0.7
Breakpoint value in progressive ratio session0.20.20.6-0.2-0.8-0.30.30.40.00.1-0.2-0.10.1-0.70.7-0.60.6
Distance traveled before self-admin0.20.20.5-0.6-0.0-0.60.70.70.00.5-0.4-0.60.6-0.10.1-0.20.2
Distance traveled after self-admin0.60.62.0-0.50.2-0.60.70.90.00.50.0-0.20.2-1.01.0-1.41.4
Delta time in closed arm before/after self-admin1.31.32.7-1.10.2-1.11.10.80.01.3-1.6-1.31.31.1-1.11.4-1.4
Delta time in open arm before/after self-admin1.21.22.51.3-0.21.5-1.5-1.60.0-1.21.11.1-1.10.6-0.60.8-0.8
Diff in mean of infusions in LGA sessions2.22.45.0-2.0-0.8-2.22.22.20.01.8-1.5-2.12.10.2-0.1-0.40.4
Extinction: sum of active levers before priming0.20.20.5-0.3-0.4-0.20.20.10.00.6-0.3-0.40.40.4-0.40.7-0.7
Active lever presses in extinction session 64.13.99.92.30.32.5-2.4-2.20.0-1.93.12.6-2.6-1.11.1-1.21.2
Delta distance traveled before/after self-admin0.30.30.70.50.20.5-0.4-0.30.0-0.30.80.7-0.7-0.60.6-0.80.8
Delta ambulatory time before/after self-admin0.60.71.40.60.30.6-0.5-0.30.0-0.60.91.0-1.0-1.11.1-1.21.2
Time in closed arm before self-admin1.61.93.31.4-0.61.5-1.4-1.20.0-1.41.71.8-1.8-1.41.4-1.31.3
Time in closed arm after self-admin0.60.72.60.0-0.2-0.10.10.30.00.10.20.5-0.5-1.61.6-1.31.3
Time in open arm before self-admin1.92.04.0-1.80.5-2.02.02.00.01.6-1.6-1.91.90.2-0.2-0.10.1
Time in open arm after self-admin0.60.72.5-0.20.1-0.10.1-0.10.00.2-0.4-0.60.61.6-1.61.4-1.4
Sum of active levers in priming session hrs 5-60.10.11.30.01.10.1-0.1-0.10.00.40.3-0.10.10.2-0.2-0.00.0
Time to tail flick, vehicle, before self-admin0.70.71.3-1.0-0.4-1.01.00.90.00.7-1.1-1.11.10.5-0.50.4-0.4
Time to tail flick, vehicle, after self-admin1.21.32.41.5-0.51.5-1.5-1.50.0-1.50.91.5-1.5-0.60.6-0.30.3
Time to tail flick, test, before self-admin0.30.31.7-0.0-1.3-0.0-0.0-0.10.0-0.3-0.6-0.30.30.5-0.50.8-0.8
Time to tail flick, test, after self-admin0.40.41.00.21.00.2-0.3-0.40.00.3-0.6-0.10.10.8-0.91.0-1.0
Delta time to tail flick, vehicle, before/after SA3.13.15.72.2-0.22.2-2.3-2.10.0-2.01.82.4-2.4-1.31.3-0.90.9
Delta time to tail flick, test, before/after SA0.40.33.40.01.80.00.00.10.00.50.30.2-0.2-0.30.3-0.50.5
Ambulatory time before self-admin0.20.30.5-0.50.1-0.50.60.70.00.4-0.3-0.40.4-0.70.7-0.60.6
Ambulatory time after self-admin0.70.82.8-0.20.3-0.30.40.70.00.30.40.2-0.2-1.51.5-1.71.7
Total heroin consumption0.10.10.40.40.40.3-0.3-0.30.0-0.60.40.3-0.3-0.40.4-0.30.3
Area under the delay curve0.40.43.00.4-1.70.4-0.4-0.30.0-0.3-0.10.5-0.5-0.60.6-0.80.8
Delay disc. indifference point, 0s delay0.30.30.80.8-0.60.8-0.8-0.90.0-0.50.40.6-0.60.4-0.40.3-0.3
Delay disc. indifference point, 16s delay0.40.41.20.2-0.90.3-0.2-0.10.0-0.10.30.6-0.6-1.11.1-1.01.0
Delay disc. indifference point, 2s delay0.80.92.01.30.51.4-1.4-1.40.0-1.11.01.2-1.2-0.20.2-0.40.4
Delay disc. indifference point, 24s delay0.70.71.6-0.8-1.2-0.91.01.00.00.6-1.3-0.70.7-0.60.5-0.60.6
Delay disc. indifference point, 4s delay0.40.42.20.7-1.50.8-0.8-0.90.0-0.1-0.20.4-0.40.4-0.40.2-0.2
Delay disc. indifference point, 8s delay0.70.85.80.6-2.40.6-0.6-0.50.0-0.90.20.7-0.7-0.70.7-0.60.6
Delay discount exponential model param0.40.53.2-0.41.8-0.40.40.30.00.30.0-0.50.50.7-0.70.8-0.8
Delay discount hyperbolic model param0.40.42.4-0.51.5-0.60.60.50.00.3-0.0-0.60.60.5-0.50.6-0.6
Fecal boli incidents, locomotor time 10.80.91.81.10.31.1-1.2-1.10.0-1.10.61.3-1.3-0.90.9-0.10.1
Change in fecal boli incidents, locomotor task0.60.62.3-0.8-1.5-0.80.91.00.00.9-0.2-0.80.8-0.20.2-0.50.5
Time >=10cm from walls, locomotor time 11.71.73.11.6-0.11.7-1.7-1.50.0-1.61.71.8-1.8-0.80.8-0.40.4
Bouts of movement, locomotor time 10.10.10.30.40.60.5-0.5-0.50.0-0.30.10.4-0.4-0.30.3-0.20.2
Total resting periods, locomotor time 10.20.30.70.40.30.4-0.4-0.30.0-0.30.30.5-0.5-0.80.8-0.80.8
Rest time, locomotor task time 10.60.62.00.3-0.70.3-0.3-0.00.00.10.20.5-0.5-1.31.3-1.41.4
Distance moved, locomotor task time 10.80.92.8-0.3-0.0-0.30.2-0.10.00.1-0.8-0.60.61.7-1.71.6-1.6
Vertical activity count, locomotor time 10.50.51.60.1-0.40.0-0.0-0.30.0-0.6-0.5-0.20.21.3-1.31.2-1.2
Time >=10cm from walls, locomotor time 20.50.51.51.00.01.1-1.1-1.20.0-0.70.70.8-0.80.3-0.30.2-0.2
Bouts of movement, locomotor time 20.40.51.10.80.70.9-1.0-1.00.0-0.11.10.6-0.60.4-0.40.4-0.4
Total resting periods, locomotor time 20.30.30.80.70.70.7-0.8-0.80.0-0.10.90.5-0.50.2-0.20.3-0.3
Rest time, locomotor task time 20.81.02.6-1.3-1.0-1.51.41.60.01.1-0.8-0.90.9-0.60.6-0.10.1
Distance moved, locomotor task time 20.91.12.91.2-0.41.4-1.4-1.70.0-1.00.30.8-0.81.2-1.20.8-0.8
Vertical activity count, locomotor time 20.60.72.30.40.30.5-0.5-0.90.0-0.5-0.4-0.00.01.5-1.51.2-1.2
Weight adjusted by age0.91.02.8-0.10.1-0.1-0.0-0.30.00.5-1.0-0.70.71.7-1.71.7-1.7
Seeking ratio, delayed vs. immediate footshock1.31.44.2-1.4-0.2-1.61.61.70.01.3-2.1-1.31.3-0.50.5-0.50.5
Locomotion in novel chamber0.91.12.41.3-0.31.4-1.3-1.30.0-1.20.91.5-1.5-0.70.7-0.50.5
Locomotion in novel chamber post-restriction3.74.37.72.6-1.62.8-2.7-2.50.0-2.41.92.7-2.7-1.41.4-0.80.8
Progressive ratio0.40.41.10.5-0.80.3-0.3-0.20.0-0.9-0.40.5-0.5-1.01.0-0.80.8
Food seeking constrained by brief footshock1.11.42.71.30.11.4-1.4-1.60.0-0.71.11.0-1.01.2-1.21.4-1.4
Seeking ratio, punishment vs. effort1.01.33.60.51.00.7-0.7-1.00.00.20.90.2-0.21.9-1.91.8-1.8
Run reversals in cocaine runway, females3.43.46.0-1.51.5-1.51.41.00.01.6-2.2-2.02.02.3-2.32.4-2.4
Run reversals in cocaine runway, males0.30.31.00.3-0.30.3-0.4-0.30.0-0.40.40.5-0.5-1.01.0-0.70.7
Latency to leave start box in cocaine runway1.01.12.3-1.31.0-1.41.41.50.01.3-0.6-1.21.2-0.10.2-0.80.8
Latency to leave start box in cocaine runway, F1.11.22.2-1.41.2-1.51.51.40.01.2-1.1-1.41.40.4-0.3-0.20.2
Latency to leave start box in cocaine runway, M0.40.41.7-0.1-0.2-0.20.20.40.00.00.60.2-0.2-0.90.9-1.31.3
Cd content in liver1.31.42.5-1.50.5-1.51.51.40.01.1-1.5-1.61.60.7-0.70.6-0.6
Co content in liver0.60.71.90.6-0.90.4-0.4-0.60.00.7-0.7-0.00.01.1-1.21.4-1.4
Cu content in liver0.50.61.70.3-0.70.7-0.7-0.90.00.40.4-0.30.31.3-1.30.9-0.9
Fe content in liver0.10.10.8-0.5-0.4-0.30.30.20.0-0.1-0.9-0.30.30.0-0.00.1-0.1
K content in liver0.20.21.0-0.3-0.3-0.30.30.40.01.00.4-0.40.40.3-0.3-0.10.1
Mg content in liver0.10.10.50.40.50.5-0.5-0.50.0-0.00.70.4-0.40.1-0.1-0.20.2
Mn content in liver0.80.92.9-0.7-0.3-0.70.71.00.00.30.3-0.30.3-1.41.4-1.71.7
Na content in liver1.31.43.51.20.41.3-1.3-1.00.0-0.91.91.5-1.5-0.90.9-1.21.2
Rb content in liver0.30.40.80.6-0.60.8-0.7-0.90.0-0.20.4-0.00.00.8-0.80.8-0.8
Se content in liver1.92.35.3-2.00.2-2.02.02.30.01.8-0.9-1.31.3-1.11.1-1.71.7
Sr content in liver0.10.10.40.1-0.20.1-0.1-0.00.0-0.1-0.20.3-0.3-0.70.6-0.40.4
Zn content in liver2.42.76.52.10.12.4-2.4-2.50.0-2.01.91.6-1.60.8-0.80.8-0.8