Hub : Genes

Gdpd5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000036859 0.08 0.05 3.1e-08 0.03 0.05 0.05 0.05 2.1e-04 1.6e-06 1.7e-06 3.5e-06
2 BLA gene expression ENSRNOG00000036859 0.19 0.13 7.0e-06 0.1 0.09 0.09 0.1 5.1e-06 1.5e-05 2.4e-05 5.4e-06
3 Brain gene expression ENSRNOG00000036859 0.46 0.17 0.0e+00 0.27 0.3 0.3 0.3 5.0e-25 1.0e-28 3.9e-28 1.6e-28
4 Brain isoform ratio ENSRNOT00000055321 0.04 0.03 5.4e-03 0 0.02 0 0.01 9.4e-02 5.7e-03 1.2e-01 2.7e-02
5 Brain isoform ratio ENSRNOT00000111969 0.04 0.03 4.6e-03 0.01 0.02 0.01 0.01 8.5e-02 4.4e-03 7.7e-02 2.3e-02
6 Brain intron excision ratio chr1:153680398:153723199 0.11 0.09 1.1e-05 0.06 0.06 0.06 0.06 3.9e-06 2.1e-06 4.4e-06 3.3e-06
7 Brain mRNA stability ENSRNOG00000036859 0.05 0.04 7.7e-04 0.04 0.04 0.03 0.04 1.2e-04 1.8e-04 6.8e-04 2.6e-04
8 Eye gene expression ENSRNOG00000036859 0.66 0.15 2.6e-06 0.2 0.12 0.14 0.17 5.5e-04 6.0e-03 4.2e-03 1.6e-03
9 IL gene expression ENSRNOG00000036859 0.4 0.17 6.6e-06 0.24 0.19 0.15 0.2 1.8e-06 2.3e-05 1.6e-04 1.2e-05
10 NAcc gene expression ENSRNOG00000036859 0.07 0.05 6.9e-05 0.03 0.04 0.04 0.04 5.5e-03 6.5e-04 1.0e-03 7.7e-04
11 NAcc intron excision ratio chr1:153680398:153723199 0.04 0.03 2.6e-03 0.01 0.03 0.02 0.02 3.5e-02 2.9e-03 9.4e-03 1.7e-02
12 PL gene expression ENSRNOG00000036859 0.26 0.12 4.9e-15 0.19 0.18 0.19 0.19 4.0e-14 1.1e-13 1.0e-14 1.3e-14
13 PL isoform ratio ENSRNOT00000055321 0.03 0.02 9.2e-03 0 0.01 0.01 0.01 2.3e-01 5.0e-02 8.8e-02 7.9e-02
14 PL intron excision ratio chr1:153756067:153758421 0.04 0.03 1.8e-03 0.02 0.01 0.02 0.01 1.6e-02 3.1e-02 1.3e-02 5.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.10.20.60.30.60.40.4-0.40.60.4-0.40.50.40.40.7-0.6-0.5
BMI without tail2.86.09.02.42.62.40.4-0.32.61.6-3.02.92.52.72.8-2.9-2.8
Body weight1.56.29.72.43.12.60.7-0.62.81.6-2.72.82.52.63.1-3.0-2.6
Epididymis fat weight1.12.55.21.12.01.41.5-1.51.51.9-1.51.81.21.32.3-1.8-1.2
Glucose0.10.10.3-0.4-0.4-0.4-0.00.0-0.4-0.20.5-0.5-0.4-0.4-0.40.40.3
Heart weight0.30.51.50.80.20.7-1.21.20.5-1.0-0.60.50.70.7-0.1-0.3-0.2
Left kidney weight1.85.37.82.72.72.8-0.70.82.70.3-2.42.22.72.62.4-2.5-2.5
Right kidney weight1.23.55.52.22.32.4-0.40.42.10.5-2.12.02.12.12.1-2.1-1.8
Tail length5.817.523.34.64.84.7-0.40.54.71.6-4.74.64.64.74.6-4.8-4.7
Length with tail2.810.215.33.33.93.60.4-0.43.51.8-3.53.63.43.43.8-3.7-3.3
Length without tail0.30.61.3-0.9-0.4-0.70.7-0.7-0.6-0.01.1-0.9-0.9-0.9-0.40.81.2
Liver weight, left1.21.94.00.81.51.01.5-1.41.12.0-1.61.60.91.01.8-1.5-1.2
Liver weight, right2.33.89.20.92.01.32.5-2.51.33.0-2.02.01.01.22.7-1.9-1.2
Parametrial fat weight0.81.62.80.51.40.61.5-1.41.01.7-1.41.60.70.91.6-1.4-1.1
Retroperitoneal fat weight3.110.222.91.23.41.64.2-4.22.34.8-3.23.21.61.94.4-3.3-2.6
Intraocular pressure0.60.92.2-0.5-0.9-0.6-1.21.2-0.5-1.50.8-1.1-0.5-0.6-1.20.90.7
Extensor digitorum longus weight0.52.14.11.11.51.10.8-0.71.31.2-2.02.01.31.41.7-1.7-1.5
Soleus weight1.64.87.61.82.51.91.1-1.12.12.0-2.82.72.02.22.7-2.6-2.2
Tibialis anterior weight0.41.21.71.21.31.1-0.20.21.30.2-1.31.31.21.31.2-1.3-1.2
Tibia length0.82.18.20.3-0.80.1-2.72.7-0.1-2.91.1-1.20.2-0.1-1.50.90.7
Number of licking bursts1.72.07.5-1.4-0.2-1.22.7-2.7-0.82.20.2-0.2-1.2-1.00.40.30.5
Food consumed during 24 hour testing period0.81.03.81.2-0.01.3-1.91.90.3-1.2-0.20.30.90.8-0.3-0.2-0.2
Times rat made contact with spout0.80.91.90.70.90.70.9-0.90.61.4-1.21.30.60.81.2-1.1-1.0
Mean time between licks in bursts6.18.513.83.63.23.7-1.61.63.4-0.3-2.62.73.53.32.8-3.0-3.3
Mean num. licks in bursts1.61.96.01.60.41.4-2.42.50.9-1.8-0.70.71.41.3-0.1-0.6-0.8
Std. dev. time between licks in bursts3.33.96.22.22.42.3-0.40.42.40.5-1.91.82.32.22.3-2.2-2.5
Water consumed over 24 hours0.60.71.4-0.8-0.8-0.71.1-1.1-1.11.20.2-0.1-0.9-0.8-0.40.60.8
Indifference point 0 sec2.74.310.42.41.32.0-3.23.22.0-2.5-1.21.32.32.20.4-1.3-1.6
Indifference point AUC0.80.91.30.91.10.90.1-0.11.10.5-1.01.01.01.01.2-1.1-1.1
Indifference point function ln k1.01.34.3-0.2-1.1-0.4-1.81.8-0.6-2.11.1-1.0-0.3-0.4-1.51.00.7
Indifference point function log k1.01.34.3-0.2-1.1-0.4-1.81.8-0.6-2.11.1-1.0-0.3-0.4-1.51.00.7
Delay discounting total patch changes 0 sec2.23.58.32.11.21.9-2.92.91.9-2.3-1.11.12.12.00.4-1.2-1.5
Delay discounting total patch changes 12 sec2.22.94.22.01.71.9-1.21.22.0-0.4-1.81.72.02.01.4-1.8-1.8
Delay discounting total patch changes 18 sec2.02.64.02.01.51.9-1.51.51.7-0.6-1.61.71.91.91.1-1.6-1.8
Delay discounting total patch changes 24 sec0.70.91.81.11.21.3-0.50.51.3-0.3-0.50.61.21.01.1-1.0-0.9
Delay discounting total patch changes 6 sec0.50.72.50.80.10.5-1.61.60.6-1.4-0.40.30.80.7-0.3-0.3-0.4
Delay discounting time to switch 0 sec2.53.86.1-2.4-1.5-2.22.4-2.5-2.11.61.6-1.5-2.3-2.2-1.01.61.7
Delay discounting water rate 0 sec1.52.36.21.70.91.6-2.52.51.5-1.9-0.80.71.71.50.2-0.9-1.0
Delay discounting water rate 12 sec0.71.04.20.9-0.20.7-2.02.00.4-1.7-0.1-0.10.70.6-0.5-0.0-0.2
Delay discounting water rate 18 sec0.40.61.01.00.51.0-1.01.00.8-0.6-0.60.40.90.90.4-0.6-0.4
Delay discounting water rate 24 sec0.91.23.3-0.2-1.1-0.3-1.61.6-0.7-1.81.0-1.0-0.4-0.5-1.41.00.8
Delay discounting water rate 6 sec0.30.51.80.2-0.6-0.0-1.31.3-0.1-1.40.3-0.40.10.0-0.80.40.2
Locomotor activity0.40.61.60.9-0.00.9-1.21.20.3-0.8-0.80.60.80.8-0.1-0.4-0.4
Locomotor testing distance1.32.23.71.90.91.9-1.81.81.4-1.1-1.41.31.81.70.6-1.2-1.3
Locomotor testing rearing1.62.53.81.91.61.9-0.70.71.80.1-1.71.71.91.81.5-1.7-1.7
Light reinforcement 10.61.24.2-1.0-0.2-0.82.0-2.0-0.81.90.0-0.2-0.9-0.80.30.20.5
Light reinforcement 20.20.30.6-0.5-0.6-0.50.2-0.2-0.70.10.5-0.6-0.6-0.6-0.60.60.8
Reaction time number correct0.81.21.8-0.8-1.3-0.8-0.60.6-1.2-0.91.2-1.3-1.0-1.1-1.31.31.3
Reaction time mean minus median0.91.21.71.31.01.2-0.90.91.2-0.4-1.11.21.31.30.6-1.1-1.2
Reaction time mean minus median AUC0.60.71.41.00.50.9-1.21.20.8-0.8-0.70.81.00.90.1-0.6-0.6
Reaction time num false alarms0.60.93.6-0.50.4-0.31.9-1.9-0.21.8-0.20.2-0.5-0.40.8-0.20.2
Reaction time num false alarms AUC0.40.52.1-0.60.1-0.41.5-1.5-0.41.40.2-0.1-0.5-0.50.40.10.4
Reaction time trials correct on left0.81.21.8-0.8-1.3-0.8-0.60.6-1.2-0.91.2-1.3-1.0-1.1-1.31.31.3
Reaction time trials on left0.81.21.8-0.8-1.4-0.8-0.60.6-1.2-0.91.2-1.3-1.0-1.1-1.31.41.3
Reaction time mean0.30.41.3-0.10.6-0.11.1-1.10.31.1-0.70.70.10.20.7-0.6-0.4
Reaction time mean AUC0.40.52.0-0.50.2-0.41.4-1.4-0.11.2-0.30.4-0.3-0.20.4-0.2-0.0
Median of all reaction times0.40.62.4-0.60.2-0.61.5-1.5-0.11.2-0.30.3-0.4-0.30.5-0.20.0
Reaction time omissions0.10.10.40.00.30.10.6-0.60.40.4-0.20.30.10.20.6-0.4-0.1
Reaction time false alarm rate0.60.83.1-0.30.7-0.11.7-1.70.11.7-0.30.4-0.2-0.11.0-0.5-0.1
Reaction time premature initiation rate4.15.57.82.62.62.4-0.80.82.70.1-2.72.72.72.82.2-2.7-2.8
Reaction time premature initiations1.72.43.51.81.51.7-1.21.21.7-0.6-1.71.71.81.91.2-1.6-1.7
Std. dev. reaction times1.21.62.61.31.51.2-0.00.01.50.4-1.51.61.41.51.3-1.6-1.5
Reaction time trials completed0.81.21.8-0.8-1.4-0.8-0.60.6-1.2-0.91.2-1.3-1.0-1.1-1.31.41.3
Reaction time trials AUC0.60.81.3-0.6-1.1-0.6-0.60.6-1.0-0.81.0-1.1-0.8-0.9-1.11.11.1
Social response proportion0.30.31.3-0.10.20.11.0-1.00.01.1-0.40.4-0.00.00.6-0.30.1
Social responses0.91.12.80.61.10.81.2-1.20.81.7-1.11.00.60.71.5-1.1-0.7
Social time2.33.04.6-2.1-1.2-1.71.9-1.9-1.81.21.5-1.8-2.0-2.1-0.71.62.1
Conditioned locomotion0.20.30.5-0.5-0.7-0.6-0.10.1-0.6-0.30.6-0.6-0.6-0.6-0.70.60.6
Cocaine response after cond. corrected0.70.83.3-0.60.5-0.41.8-1.80.01.40.1-0.0-0.4-0.40.8-0.20.0
Cocaine response after cond. not corrected0.30.31.1-0.60.2-0.31.0-1.0-0.10.60.4-0.4-0.4-0.50.30.10.2
Cocaine response before conditioning0.50.62.40.2-0.70.1-1.51.5-0.4-1.30.4-0.40.0-0.0-1.10.50.4
Saline control response1.41.93.41.81.31.8-1.21.21.6-0.6-1.21.21.71.61.1-1.3-1.3
Condit. Reinf. active minus inactive responses4.45.48.52.92.22.9-2.72.72.8-1.8-1.51.52.82.61.4-2.0-2.0
Condit. Reinf. active-inactive response ratio0.60.61.50.90.71.0-1.21.20.9-1.1-0.0-0.10.90.70.2-0.4-0.4
Condit. Reinf. active responses6.99.615.03.93.03.9-3.03.03.6-1.7-2.52.53.83.62.1-2.9-2.9
Condit. Reinf. inactive responses5.26.510.13.22.53.2-1.91.92.8-0.6-2.62.63.13.02.0-2.6-2.6
Condit. Reinf. lever presses9.212.625.24.22.63.9-5.05.03.8-3.7-2.22.14.13.91.2-2.6-3.0
Condit. Reinf. lever reinforcers received6.99.815.23.92.93.9-3.43.43.6-2.0-2.32.33.83.61.9-2.8-2.9
Pavlov. Cond. lever latency8.812.128.3-4.0-2.3-3.85.3-5.3-3.64.11.8-1.7-3.9-3.6-0.82.22.6
Pavlov. Cond. magazine entry latency2.02.28.21.30.31.0-2.92.91.1-2.7-0.20.31.31.1-0.5-0.4-0.7
Pavlov. Cond. change in total contacts5.77.922.13.11.62.9-4.74.72.8-3.9-0.80.83.02.60.3-1.4-1.8
Pavlov. Cond. index score6.78.723.03.31.73.0-4.84.83.0-4.0-1.21.23.22.90.4-1.7-2.1
Pavlov. Cond. latency score5.97.520.73.01.52.7-4.54.62.7-3.9-0.91.02.92.60.2-1.5-1.8
Pavlov. Cond. lever contacts9.212.830.34.12.33.8-5.55.53.7-4.3-1.81.84.03.70.7-2.3-2.7
Pavlov. Cond. magazine entry number2.93.613.0-1.7-0.5-1.53.6-3.6-1.53.30.0-0.1-1.7-1.40.50.40.8
Pavlov. Cond. intertrial magazine entries1.52.03.21.21.61.40.8-0.81.31.5-1.71.61.21.31.8-1.6-1.4
Pavlov. Cond. lever-magazine prob. diff.6.48.320.83.21.83.0-4.54.63.0-3.8-1.11.23.22.90.5-1.7-2.1
Pavlov. Cond. response bias9.112.531.74.02.13.7-5.65.63.5-4.5-1.71.73.93.60.5-2.2-2.6
Conditioned reinforcement - actives1.01.04.50.2-0.50.0-1.81.8-0.0-2.10.8-0.70.1-0.1-1.00.60.4
Conditioned reinforcement - inactives0.20.21.0-0.5-0.0-0.31.0-1.0-0.20.70.2-0.2-0.4-0.40.30.10.2
Conditioned locomotion1.31.54.4-0.4-1.2-0.5-1.71.6-0.8-2.11.2-1.2-0.5-0.6-1.61.21.1
Intermittent access intake day 1-15 change0.50.52.30.2-0.20.0-1.31.30.1-1.50.4-0.40.20.1-0.60.20.0
Intermittent access intake escalation0.60.62.90.3-0.30.1-1.51.50.2-1.70.4-0.40.30.2-0.70.30.0
Intermittent access intake escalation 20.30.30.60.50.30.4-0.80.80.6-0.8-0.20.20.60.50.1-0.3-0.5
Intermitt. access day 1 inactive lever presses0.20.21.0-0.40.0-0.21.0-1.0-0.10.90.1-0.1-0.3-0.30.40.10.2
Intermitt. access day 15 inactive lever presses0.30.40.9-0.5-0.7-0.5-0.00.0-0.7-0.20.6-0.6-0.6-0.6-0.70.71.0
Intermitt. access escalation Index0.10.10.20.3-0.00.3-0.40.40.1-0.0-0.40.40.20.3-0.1-0.20.1
Intermittent access day 1 total infusions0.40.50.80.90.50.8-0.60.60.7-0.1-0.90.90.80.90.4-0.7-0.7
Intermittent access day 15 total infusions0.40.51.90.5-0.10.3-1.41.40.3-1.4-0.00.10.50.4-0.5-0.0-0.2
Intermittent access terminal intake (last 3 days)0.40.41.30.70.20.5-1.11.10.5-1.0-0.30.40.60.6-0.1-0.3-0.4
Intermittent access total infusions0.20.20.50.60.20.5-0.70.70.4-0.5-0.40.50.50.50.0-0.4-0.4
Intermittent access day 1 locomotion0.20.20.4-0.4-0.6-0.4-0.10.1-0.6-0.20.3-0.3-0.4-0.4-0.60.50.5
Intermittent access day 15 total locomotion0.40.51.80.2-0.50.0-1.31.3-0.2-1.30.3-0.30.10.0-0.80.40.2
Intermittent access total locomotion0.10.10.40.3-0.00.3-0.60.60.1-0.6-0.10.10.30.3-0.2-0.1-0.1
Intermittent access standard deviation0.10.20.30.50.50.5-0.10.10.50.0-0.30.40.50.40.5-0.4-0.4
Cocaine induced anxiety0.80.92.3-1.1-0.6-1.01.5-1.5-0.91.10.5-0.6-1.1-1.0-0.20.60.7
Post-drug Anxiety0.20.20.8-0.40.1-0.40.9-0.9-0.20.70.0-0.1-0.3-0.30.20.00.0
Baseline Anxiety1.01.01.81.20.81.0-1.31.31.1-1.0-0.70.71.21.10.4-0.8-1.0
Lifetime Intake0.30.30.80.60.30.5-0.90.90.5-0.7-0.30.40.60.60.0-0.4-0.5
Incentive Sensitization - Responses1.71.72.51.61.11.4-1.51.61.5-1.0-1.01.01.61.50.6-1.2-1.3
Incentive Sensitization - Breakpoint1.51.52.61.50.91.3-1.61.61.3-1.1-0.80.91.41.40.4-1.0-1.1
Progressive ratio test 1 active lever presses0.30.30.5-0.7-0.3-0.70.6-0.6-0.50.10.5-0.5-0.6-0.6-0.30.40.4
Progressive ratio test 1 breakpoint0.10.20.4-0.5-0.1-0.50.6-0.6-0.30.20.3-0.3-0.4-0.4-0.10.20.2
Progressive ratio test 1 inactive lever presses0.10.10.20.30.30.3-0.10.10.5-0.1-0.30.30.40.40.3-0.4-0.4
Progressive ratio test 2 active lever presses0.60.70.90.90.70.8-1.01.01.0-0.8-0.50.61.00.90.4-0.7-0.9
Progressive ratio test 2 breakpoint0.70.81.11.00.80.9-1.01.01.0-0.8-0.60.61.01.00.5-0.8-1.0
Progressive ratio test 2 inactive lever presses0.10.20.60.3-0.10.2-0.80.80.1-0.6-0.20.20.30.3-0.3-0.10.0
Total sessions with >9 infusions0.80.93.40.7-0.00.4-1.81.80.4-1.80.00.00.60.6-0.6-0.0-0.4
Short access day 1 total inactive lever presses0.20.30.4-0.6-0.4-0.50.6-0.6-0.60.60.3-0.3-0.6-0.5-0.20.40.6
Short access day 10 total inactive lever presses0.20.20.3-0.5-0.5-0.50.3-0.3-0.50.10.4-0.4-0.5-0.5-0.40.50.6
Short access day 1 total infusions1.01.11.91.20.81.1-1.41.41.1-1.0-0.70.71.21.10.4-0.8-0.9
Short access day 10 total infusions0.60.60.91.00.81.0-0.60.71.0-0.4-0.60.71.00.90.6-0.8-0.8
Short access total infusions0.50.60.80.90.70.8-0.60.60.9-0.4-0.70.70.90.90.5-0.8-0.9
Short access day 1 locomotion1.21.35.4-0.2-0.8-0.4-1.81.8-0.2-2.31.1-1.1-0.2-0.4-1.30.90.5
Short access day 10 total locomotion0.10.10.40.40.10.4-0.60.60.3-0.6-0.00.00.30.30.0-0.1-0.2
Short access total locomotion0.10.10.4-0.1-0.2-0.1-0.40.4-0.0-0.60.3-0.3-0.1-0.1-0.30.2-0.0
Compulsive drug intake0.50.50.7-0.5-0.6-0.5-0.50.5-0.6-0.80.9-0.9-0.5-0.6-0.90.80.8
One hour access (0.3 mA shock)0.70.92.61.00.30.8-1.61.60.7-1.4-0.40.40.90.9-0.1-0.4-0.6
One hour access (shock baseline)0.50.61.20.90.50.8-1.11.10.8-0.9-0.50.50.90.80.2-0.6-0.7
Number of responses in last shaping day0.90.91.51.10.91.1-0.20.21.00.5-1.21.21.11.10.9-1.1-1.0
Context. condit. distance diff. score1.11.36.00.6-0.40.2-2.32.30.4-2.40.2-0.20.60.5-1.00.1-0.3
Locomotion velocity, session 11.21.22.2-1.1-1.2-0.90.2-0.2-1.3-0.31.5-1.5-1.2-1.3-1.11.41.2
Locomotion distance, session 10.50.72.1-0.1-0.5-0.0-1.11.1-0.3-1.51.2-1.2-0.3-0.5-0.80.80.6
Locomotion velocity, session 20.00.00.20.20.30.40.0-0.00.10.20.2-0.10.10.00.3-0.00.0
Locomotion distance, session 20.10.10.50.2-0.10.4-0.70.7-0.1-0.50.4-0.40.1-0.0-0.30.30.2
Locomotion velocity, session 30.60.71.7-0.3-0.8-0.3-1.11.1-0.5-1.30.9-1.0-0.3-0.5-1.00.80.6
Locomotion distance, session 31.01.12.6-0.3-1.0-0.3-1.51.5-0.6-1.61.1-1.2-0.4-0.6-1.31.00.8
Stereotopy head waving bouts, day 30.30.41.20.20.60.40.9-0.90.41.1-0.60.60.30.30.9-0.6-0.4
Stereotopy head waving duration, day 30.10.10.30.1-0.3-0.0-0.60.6-0.1-0.5-0.00.00.10.1-0.30.1-0.1
Locomotion velocity, session 70.40.40.6-0.8-0.6-0.80.2-0.2-0.6-0.10.7-0.7-0.7-0.7-0.60.70.7
Locomotion distance, session 70.00.00.1-0.20.1-0.20.2-0.20.00.1-0.0-0.0-0.1-0.10.0-0.0-0.1
Stereotopy head waving bouts, day 70.60.62.80.6-0.10.6-1.71.70.3-1.30.4-0.30.50.3-0.50.20.1
Stereotopy head waving duration, day 70.81.03.51.20.31.1-1.91.90.7-1.3-0.20.31.00.9-0.1-0.4-0.4
Locomotion velocity, session 80.50.61.80.70.00.4-1.31.30.4-1.1-0.50.60.70.7-0.3-0.3-0.6
Locomotion distance, session 80.71.14.40.8-0.00.7-2.12.10.5-2.10.3-0.30.70.5-0.50.1-0.3
Degree of sensitization distance2.22.23.81.01.71.01.2-1.21.41.5-1.71.81.11.32.0-1.7-1.5
Degree of sensitization stereotypy1.41.56.21.1-0.01.0-2.52.50.5-2.10.5-0.50.80.6-0.60.10.0
Condit. Reinf. active minus inactive responses0.80.91.51.00.91.1-0.10.10.90.4-1.21.21.01.10.9-1.1-0.9
Condit. Reinf. active-inactive response ratio1.71.83.21.51.21.4-0.40.41.40.2-1.71.81.51.61.2-1.5-1.5
Condit. Reinf. active responses0.20.20.40.50.50.60.2-0.20.40.5-0.60.60.40.50.6-0.5-0.4
Condit. Reinf. inactive responses0.20.20.5-0.4-0.3-0.30.2-0.2-0.50.30.6-0.7-0.5-0.6-0.30.60.6
Incentive salience index mean0.60.71.21.00.91.1-0.20.20.80.3-1.00.90.91.00.8-0.9-0.8
Condit. Reinf. lever presses0.10.10.40.60.40.6-0.30.30.30.0-0.40.30.50.40.3-0.3-0.3
Time in familiar zone, hab. session 10.30.20.60.30.50.40.5-0.50.30.8-0.50.60.30.40.6-0.5-0.5
Time in novel zone, hab. session 10.00.00.1-0.2-0.1-0.20.3-0.3-0.00.1-0.10.1-0.1-0.10.1-0.0-0.0
Total zone transitions, hab. session 10.50.71.4-0.6-1.1-0.8-0.70.6-0.8-1.00.8-0.8-0.7-0.7-1.20.90.6
Total locomotion distance, hab. session 10.81.12.40.51.20.71.3-1.30.81.5-1.01.00.60.61.5-1.1-1.0
Locomotion velocity, hab. session 10.40.61.30.40.90.60.9-0.90.71.1-0.80.80.50.51.1-0.8-0.8
Time in familiar zone, hab. session 21.41.42.21.50.91.2-1.01.01.1-0.2-1.41.51.41.50.7-1.2-1.4
Time in novel zone, hab. session 20.90.91.9-1.1-0.8-0.80.4-0.4-0.8-0.21.4-1.4-1.0-1.2-0.71.11.2
Total zone transitions, hab. session 20.81.04.10.1-0.50.1-1.71.7-0.1-2.00.8-0.90.0-0.2-1.00.70.5
Total locomotion distance, hab. session 21.11.42.71.11.61.40.5-0.51.30.9-1.21.21.21.11.6-1.4-1.0
Locomotion velocity, hab. session 21.21.63.31.11.71.40.7-0.71.41.1-1.31.21.21.21.8-1.4-1.1
Novel to familiar place preference ratio0.10.10.4-0.1-0.1-0.0-0.20.20.1-0.60.4-0.5-0.1-0.2-0.10.20.3
Novelty place preference0.10.10.3-0.2-0.1-0.0-0.10.10.0-0.50.5-0.6-0.1-0.3-0.10.30.4
Time in novel zone, NPP test0.10.10.5-0.0-0.10.1-0.40.40.1-0.70.4-0.5-0.0-0.1-0.20.20.3
Total zone transitions, NPP test0.30.50.8-0.4-0.7-0.3-0.60.6-0.6-0.90.9-0.9-0.5-0.6-0.80.80.8
Total locomotion distance, NPP test0.50.71.90.31.10.71.4-1.40.61.4-0.30.30.30.21.4-0.7-0.3
Locomotion velocity, NPP test0.60.82.8-0.01.00.51.7-1.70.41.6-0.20.10.0-0.01.3-0.5-0.0
Pavlov. Cond. lever latency0.81.11.9-1.4-0.8-1.31.1-1.1-0.90.41.0-1.0-1.2-1.2-0.60.91.0
Pavlov. Cond. magazine entry latency2.12.74.12.01.42.0-1.91.91.7-1.2-1.41.32.01.90.8-1.4-1.4
Pavlov. Cond. change in total contacts0.70.81.71.20.91.3-1.01.01.0-0.5-0.50.51.10.90.6-0.7-0.6
Pavlov. Cond. index score2.32.94.92.21.52.1-1.71.71.7-0.8-1.61.62.02.01.0-1.5-1.6
Pavlov. Cond. latency score2.12.74.52.11.42.1-1.81.81.6-0.8-1.51.52.01.90.9-1.4-1.5
Pavlov. Cond. lever contacts1.31.52.81.61.11.7-0.90.91.2-0.1-1.21.21.51.41.0-1.2-1.2
Pavlov. Cond. magazine entry number2.02.54.4-2.0-1.2-1.92.1-2.1-1.61.41.2-1.2-1.9-1.8-0.61.21.4
Pavlov. Cond. intertrial magazine entries1.21.42.3-1.3-0.9-1.11.5-1.5-1.31.21.0-1.1-1.4-1.4-0.41.01.2
Pavlov. Cond. lever-magazine prob. diff.1.92.34.02.01.31.9-1.51.51.5-0.6-1.51.51.81.80.9-1.4-1.4
Pavlov. Cond. response bias1.21.42.61.61.11.6-0.90.91.2-0.2-1.21.21.41.40.9-1.1-1.1
Bone: apparent density0.10.20.7-0.3-0.9-0.40.2-0.2-0.80.5-0.60.5-0.4-0.1-0.60.20.5
Bone surface0.81.32.91.40.41.1-1.21.20.8-0.5-1.71.61.31.40.3-1.1-1.0
Bone volume0.50.82.31.10.20.9-0.80.80.5-0.0-1.51.50.91.10.2-0.9-0.6
Bone: connectivity density0.20.31.1-0.2-1.1-0.5-0.60.6-0.7-0.3-0.50.4-0.3-0.1-1.00.30.4
Bone: cortical apparent density0.60.82.9-0.30.4-0.21.7-1.7-0.11.7-0.60.7-0.2-0.10.8-0.4-0.5
Bone: cortical area0.71.12.01.20.91.1-0.60.61.1-0.2-1.41.41.21.30.8-1.2-1.2
Bone: cortical porosity0.70.72.6-0.1-0.5-0.2-1.41.4-0.2-1.60.9-0.9-0.2-0.3-1.00.70.6
Bone: cortical porosity0.60.71.8-0.2-0.7-0.3-1.21.1-0.4-1.41.0-1.0-0.3-0.5-1.00.80.6
Bone: cortical thickness0.10.10.2-0.4-0.4-0.40.4-0.4-0.50.30.00.0-0.4-0.3-0.30.20.2
Bone: cortical thickness0.20.20.6-0.2-0.4-0.1-0.50.5-0.2-0.80.5-0.5-0.2-0.3-0.50.40.6
Bone: cortical tissue density0.60.82.9-0.30.3-0.31.7-1.7-0.21.7-0.50.6-0.3-0.10.7-0.3-0.4
Bone: elastic displacement1.51.72.8-1.7-1.4-1.71.3-1.3-1.60.50.9-0.8-1.6-1.5-0.91.21.3
Bone: elastic work1.82.43.8-1.9-1.7-1.91.2-1.2-1.90.41.3-1.1-1.9-1.8-1.31.51.6
Bone: endosteal estimation2.04.26.02.42.12.4-1.01.02.4-0.1-2.22.22.42.51.9-2.3-2.2
Bone: endosteal perimeter2.14.46.72.62.02.5-1.51.52.4-0.6-2.12.12.62.51.7-2.2-2.1
Bone: final force0.00.10.40.1-0.0-0.0-0.10.10.1-0.0-0.60.60.20.30.0-0.3-0.4
Bone: final moment0.10.20.70.40.10.3-0.20.20.3-0.0-0.80.80.40.60.2-0.5-0.6
Bone: marrow area1.84.05.62.32.12.3-0.80.82.30.0-2.22.22.32.41.9-2.2-2.1
Bone: maximum diameter1.93.55.12.31.72.1-1.71.72.1-1.0-1.81.92.32.31.2-1.9-1.9
Bone: maximum force0.10.20.70.40.10.2-0.40.40.4-0.3-0.80.80.50.60.1-0.5-0.6
Bone: maximum moment0.30.41.10.70.30.5-0.60.60.5-0.3-1.01.00.70.80.2-0.7-0.7
Bone: minimum diameter2.24.16.32.12.22.10.2-0.12.21.0-2.52.52.12.32.3-2.4-2.3
Bone: periosteal estimation1.73.65.22.21.82.1-1.01.02.1-0.3-2.12.12.22.31.7-2.1-2.0
Bone: periosteal perimeter1.93.14.82.21.52.1-1.31.31.9-0.4-2.02.12.12.21.3-1.9-1.8
Bone: post-yield work0.30.40.90.70.20.4-0.70.70.5-0.4-1.00.90.70.80.1-0.6-0.7
Bone: stiffness0.30.40.90.30.70.20.6-0.60.60.6-0.90.90.40.60.7-0.8-0.8
Bone: tissue strength2.01.92.9-1.4-1.7-1.5-0.30.3-1.4-1.01.6-1.6-1.4-1.4-1.71.61.3
Bone: trabecular number0.81.22.6-1.2-1.6-1.40.8-0.8-1.60.70.1-0.1-1.3-1.0-1.10.91.2
Bone: trabecular spacing0.40.51.90.40.30.4-1.21.20.6-1.40.7-0.70.40.2-0.10.1-0.3
Bone: trabecular thickness0.30.41.20.20.20.20.6-0.60.01.1-1.11.10.20.40.5-0.5-0.1
Bone: trabecular tissue density1.11.63.40.41.50.61.8-1.81.01.8-1.01.00.60.61.8-1.2-1.1
Breakpoint value in progressive ratio session0.30.30.5-0.7-0.4-0.70.3-0.3-0.7-0.00.7-0.7-0.7-0.7-0.50.70.7
Distance traveled before self-admin0.20.20.7-0.4-0.3-0.40.8-0.8-0.30.6-0.00.1-0.4-0.30.10.0-0.1
Distance traveled after self-admin2.32.54.1-1.8-1.7-1.80.8-0.8-2.00.21.5-1.5-1.9-1.8-1.51.72.0
Delta time in closed arm before/after self-admin2.32.23.61.01.61.01.2-1.11.41.7-1.61.81.21.31.9-1.7-1.8
Delta time in open arm before/after self-admin1.41.32.21.40.91.4-1.51.51.2-1.0-1.00.91.41.30.4-0.9-0.8
Diff in mean of infusions in LGA sessions1.11.34.0-1.2-0.4-1.12.0-2.0-0.91.60.5-0.5-1.1-1.00.10.50.6
Extinction: sum of active levers before priming0.10.10.4-0.00.30.10.6-0.60.10.6-0.10.1-0.0-0.00.4-0.20.0
Active lever presses in extinction session 62.12.18.2-0.2-0.9-0.4-2.32.2-0.4-2.91.4-1.3-0.3-0.5-1.71.21.0
Delta distance traveled before/after self-admin0.60.71.3-0.6-0.8-0.6-0.50.5-0.9-0.70.9-1.0-0.7-0.8-1.11.01.1
Delta ambulatory time before/after self-admin1.21.32.3-0.9-1.0-0.9-0.60.6-1.1-1.11.3-1.5-1.0-1.1-1.41.31.4
Time in closed arm before self-admin1.92.14.2-0.6-1.8-0.7-1.71.7-1.4-1.81.2-1.3-0.9-1.0-2.11.61.7
Time in closed arm after self-admin1.51.52.9-1.3-1.7-1.30.4-0.4-1.70.20.9-1.0-1.5-1.4-1.41.41.5
Time in open arm before self-admin1.01.14.6-0.90.2-0.82.1-2.1-0.21.60.5-0.4-0.7-0.70.8-0.0-0.3
Time in open arm after self-admin2.02.23.51.51.91.4-0.10.11.90.3-1.61.41.61.61.7-1.8-1.8
Sum of active levers in priming session hrs 5-60.00.00.2-0.10.00.10.1-0.1-0.20.10.2-0.1-0.2-0.2-0.10.20.5
Time to tail flick, vehicle, before self-admin0.10.20.6-0.1-0.5-0.10.1-0.1-0.50.7-0.80.5-0.2-0.0-0.30.10.4
Time to tail flick, vehicle, after self-admin0.60.72.80.6-0.20.5-1.71.70.3-1.60.00.10.50.5-0.60.0-0.0
Time to tail flick, test, before self-admin0.70.71.30.81.10.8-0.10.11.00.2-0.80.80.90.90.9-0.9-1.1
Time to tail flick, test, after self-admin1.01.11.91.11.31.20.1-0.11.30.4-0.90.81.11.11.4-1.2-1.3
Delta time to tail flick, vehicle, before/after SA0.90.94.90.40.20.2-1.61.60.7-2.21.0-0.70.50.2-0.40.1-0.4
Delta time to tail flick, test, before/after SA0.20.10.4-0.4-0.2-0.30.4-0.4-0.20.10.6-0.6-0.4-0.50.00.30.3
Ambulatory time before self-admin0.50.60.9-0.9-0.9-1.00.8-0.8-0.80.50.6-0.5-0.9-0.8-0.40.60.6
Ambulatory time after self-admin3.64.06.4-2.2-2.1-2.10.6-0.7-2.4-0.22.1-2.1-2.3-2.3-2.02.32.5
Total heroin consumption0.00.10.20.20.20.2-0.50.5-0.0-0.40.1-0.20.10.1-0.10.10.2
Area under the delay curve0.10.10.30.20.50.20.1-0.10.5-0.10.1-0.10.30.20.4-0.3-0.4
Delay disc. indifference point, 0s delay0.40.40.80.80.70.9-0.70.80.8-0.5-0.10.30.80.70.5-0.5-0.7
Delay disc. indifference point, 16s delay0.20.20.5-0.5-0.3-0.50.2-0.2-0.3-0.20.6-0.7-0.4-0.5-0.30.40.5
Delay disc. indifference point, 2s delay1.01.12.51.01.41.0-0.90.91.6-1.0-0.00.11.21.00.9-0.9-1.4
Delay disc. indifference point, 24s delay0.50.51.2-0.7-0.4-0.61.1-1.1-0.71.1-0.10.0-0.7-0.5-0.10.30.7
Delay disc. indifference point, 4s delay0.91.02.11.11.51.4-0.30.31.4-0.1-0.20.21.10.91.2-0.9-1.4
Delay disc. indifference point, 8s delay0.20.20.30.40.40.3-0.50.50.6-0.6-0.10.10.50.40.2-0.4-0.4
Delay discount exponential model param0.10.10.3-0.1-0.5-0.2-0.10.1-0.40.0-0.20.1-0.2-0.1-0.40.20.3
Delay discount hyperbolic model param0.20.20.6-0.4-0.8-0.40.0-0.0-0.80.1-0.00.0-0.5-0.4-0.60.40.6
Fecal boli incidents, locomotor time 10.40.51.30.1-0.60.2-1.11.1-0.5-1.10.4-0.6-0.1-0.2-0.80.60.9
Change in fecal boli incidents, locomotor task0.60.61.4-0.9-0.2-0.91.2-1.2-0.50.80.7-0.3-0.8-0.8-0.10.40.3
Time >=10cm from walls, locomotor time 10.80.83.70.2-0.20.0-1.61.60.2-1.90.7-0.70.20.0-0.80.40.3
Bouts of movement, locomotor time 10.00.00.10.00.10.1-0.20.2-0.0-0.30.3-0.2-0.0-0.1-0.10.20.2
Total resting periods, locomotor time 10.30.40.7-0.5-0.6-0.4-0.10.1-0.7-0.40.8-0.6-0.6-0.7-0.70.70.8
Rest time, locomotor task time 10.70.81.7-0.9-0.8-0.70.4-0.4-0.9-0.01.3-1.1-1.0-1.1-0.61.01.2
Distance moved, locomotor task time 11.61.83.81.31.21.1-0.30.31.40.3-1.71.71.41.61.2-1.6-2.0
Vertical activity count, locomotor time 11.51.64.21.31.20.9-0.80.81.4-0.3-1.51.31.41.50.9-1.4-2.0
Time >=10cm from walls, locomotor time 20.50.51.10.80.80.9-1.01.00.8-0.9-0.10.10.80.60.3-0.4-0.4
Bouts of movement, locomotor time 20.60.61.40.90.90.9-0.40.41.2-0.3-0.40.51.00.80.9-0.8-1.0
Total resting periods, locomotor time 20.40.41.00.60.90.6-0.20.21.0-0.3-0.10.20.70.60.8-0.6-0.9
Rest time, locomotor task time 21.21.43.3-1.5-0.8-1.41.8-1.8-1.31.30.5-0.6-1.4-1.2-0.40.80.7
Distance moved, locomotor task time 22.12.43.81.91.42.0-1.81.81.8-1.2-1.01.21.91.70.9-1.3-1.4
Vertical activity count, locomotor time 22.22.43.61.81.61.6-1.21.21.8-0.4-1.51.51.81.81.1-1.6-1.9
Weight adjusted by age1.61.82.51.51.41.6-0.30.31.50.2-1.51.41.51.51.4-1.5-1.6
Seeking ratio, delayed vs. immediate footshock1.51.73.0-1.5-1.3-1.31.3-1.3-1.70.90.8-0.9-1.6-1.5-0.81.21.5
Locomotion in novel chamber0.70.92.2-0.2-1.1-0.3-1.41.4-0.7-1.50.6-0.9-0.3-0.4-1.40.90.9
Locomotion in novel chamber post-restriction1.41.77.50.1-0.6-0.2-2.32.30.1-2.71.0-1.10.1-0.1-1.30.70.4
Progressive ratio0.20.30.6-0.3-0.6-0.3-0.40.4-0.4-0.60.5-0.7-0.3-0.4-0.60.60.8
Food seeking constrained by brief footshock1.51.83.01.61.51.7-0.90.91.7-0.4-1.11.21.71.61.3-1.4-1.3
Seeking ratio, punishment vs. effort1.92.33.51.61.91.6-0.30.31.80.3-1.51.71.71.71.7-1.7-1.9
Run reversals in cocaine runway, females5.35.28.21.82.61.81.3-1.32.32.2-2.72.72.02.22.9-2.7-2.7
Run reversals in cocaine runway, males0.00.00.1-0.2-0.1-0.30.2-0.2-0.20.2-0.10.1-0.2-0.1-0.20.1-0.2
Latency to leave start box in cocaine runway0.70.83.3-0.70.5-0.61.8-1.80.11.20.5-0.5-0.5-0.50.8-0.1-0.3
Latency to leave start box in cocaine runway, F0.90.92.8-0.11.20.11.7-1.70.81.3-0.00.10.20.11.5-0.7-0.9
Latency to leave start box in cocaine runway, M0.70.61.1-1.0-0.9-1.10.3-0.3-0.9-0.10.8-0.9-0.9-0.9-0.80.80.7
Cd content in liver0.50.51.40.20.70.31.0-1.00.41.2-0.80.80.30.40.9-0.7-0.4
Co content in liver1.72.13.31.81.71.8-0.70.81.60.1-1.31.31.71.61.3-1.5-1.6
Cu content in liver1.21.52.71.51.61.6-0.30.41.50.2-0.90.91.41.31.4-1.3-1.3
Fe content in liver0.00.00.1-0.00.30.00.2-0.20.20.1-0.10.10.10.10.2-0.2-0.3
K content in liver0.20.20.50.30.50.40.5-0.50.30.7-0.40.40.30.30.7-0.5-0.3
Mg content in liver0.10.10.20.40.30.4-0.40.40.5-0.4-0.00.00.40.40.3-0.3-0.3
Mn content in liver2.22.53.6-1.9-1.6-1.70.9-0.9-1.90.21.6-1.6-1.9-1.9-1.41.71.8
Na content in liver0.20.21.00.0-0.20.0-0.80.80.1-1.00.7-0.70.0-0.1-0.30.3-0.0
Rb content in liver0.81.01.61.20.81.1-1.01.01.0-0.3-1.11.11.21.20.5-1.0-0.9
Se content in liver2.63.15.3-2.1-1.1-1.82.3-2.3-1.91.61.5-1.5-2.1-2.0-0.61.51.7
Sr content in liver0.40.40.6-0.6-0.7-0.6-0.20.2-0.6-0.50.8-0.8-0.6-0.6-0.80.70.7
Zn content in liver2.52.76.62.01.11.8-2.62.61.7-1.9-0.80.81.91.70.4-1.0-1.3