Hub : Genes

Pcbp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio ENSRNOT00000109477 0.03 0.02 2.6e-03 0.03 0.01 0.01 0.02 8.1e-04 1.4e-02 5.8e-02 2.5e-03
2 Brain intron excision ratio chr7:133620323:133621791 0.03 0.02 3.5e-03 0.03 0.01 0 0.02 1.1e-03 5.0e-02 2.6e-01 4.4e-03
3 Eye alternative polyA ENSRNOT00000077687 0.77 0.12 6.0e-03 0.12 -0.02 0.02 0 6.8e-03 8.8e-01 1.5e-01 2.7e-01
4 Eye alternative TSS ENSRNOT00000077687 0.49 0.25 1.2e-03 0.31 0.3 0.34 0.28 1.0e-05 1.7e-05 3.8e-06 2.8e-05
5 Eye alternative TSS ENSRNOT00000099581 0.5 0.28 2.0e-03 0.31 0.29 0.35 0.28 1.1e-05 2.4e-05 2.5e-06 3.1e-05
6 Eye alternative TSS ENSRNOT00000077687 0.48 0.25 1.8e-03 0.3 0.28 0.34 0.27 1.3e-05 3.1e-05 3.8e-06 4.0e-05
7 Eye alternative TSS ENSRNOT00000099581 0.48 0.3 2.8e-03 0.29 0.28 0.35 0.26 2.2e-05 3.8e-05 2.5e-06 6.3e-05
8 Eye gene expression ENSRNOG00000036852 0.78 0.13 1.3e-04 0.28 0.13 0.28 0.26 3.0e-05 4.4e-03 3.0e-05 6.7e-05
9 Eye intron excision ratio chr7:133608265:133608861 0.59 0.15 2.2e-05 0.31 0.22 0.25 0.28 1.1e-05 2.7e-04 8.2e-05 3.1e-05
10 Eye intron excision ratio chr7:133608491:133608861 0.59 0.15 1.7e-05 0.32 0.2 0.27 0.22 7.0e-06 5.3e-04 5.2e-05 3.1e-04
11 Liver isoform ratio ENSRNOT00000105769 0.14 0.09 1.5e-12 0.12 0.11 0.1 0.11 7.1e-13 4.4e-12 3.8e-11 8.2e-12
12 PL isoform ratio ENSRNOT00000105769 0.11 0.08 4.4e-03 0.03 0.01 0.01 0.03 1.6e-03 5.0e-02 2.7e-02 3.5e-03
13 PL isoform ratio ENSRNOT00000109477 0.03 0.03 7.0e-03 0.02 0.02 0.01 0.02 1.4e-02 1.2e-02 5.1e-02 1.3e-02
14 PL intron excision ratio chr7:133620323:133621791 0.03 0.02 5.8e-03 0.01 0.02 0.01 0.02 2.6e-02 1.5e-02 6.7e-02 1.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.62.03.5-1.4-1.5-1.2-1.31.3-1.31.3-1.31.4-1.41.41.3-1.7-1.9
BMI without tail0.10.30.60.00.40.10.7-0.70.8-0.70.8-0.30.3-0.6-0.2-0.0-0.1
Body weight0.10.41.0-0.9-0.4-0.9-0.60.5-0.50.5-0.60.4-0.40.70.4-0.8-1.0
Epididymis fat weight1.12.74.71.42.11.90.7-0.70.7-0.61.7-2.22.2-1.5-2.01.91.8
Glucose0.00.00.1-0.2-0.2-0.3-0.10.1-0.10.2-0.00.2-0.2-0.10.30.00.0
Heart weight0.10.20.60.80.20.6-0.50.4-0.50.4-0.4-0.20.20.1-0.10.30.2
Left kidney weight0.20.61.2-1.0-0.4-0.9-1.11.0-1.11.0-0.40.4-0.40.30.4-0.6-0.8
Right kidney weight1.23.56.3-2.5-1.5-2.5-2.12.1-2.22.1-1.21.6-1.61.11.4-1.7-1.8
Tail length0.30.81.10.71.00.81.0-1.01.0-1.01.1-0.80.8-0.9-0.80.90.9
Length with tail0.00.00.10.30.30.20.0-0.10.1-0.1-0.1-0.20.20.0-0.20.20.2
Length without tail0.51.02.0-0.3-0.8-0.3-1.41.3-1.41.3-1.40.8-0.81.20.7-0.7-0.8
Liver weight, left0.30.61.0-0.9-0.5-0.9-0.70.7-0.60.7-1.00.5-0.50.90.4-0.9-1.0
Liver weight, right0.20.31.0-1.0-0.1-1.0-0.60.6-0.60.60.0-0.10.10.0-0.3-0.3-0.5
Parametrial fat weight4.07.89.02.73.02.92.6-2.62.6-2.62.7-2.82.8-2.8-3.03.02.9
Retroperitoneal fat weight0.41.43.01.21.41.20.5-0.50.4-0.41.2-1.11.1-1.0-1.51.71.7
Intraocular pressure0.81.12.0-0.4-1.2-0.5-1.01.0-1.01.0-1.21.3-1.31.31.4-0.8-0.7
Extensor digitorum longus weight5.622.331.9-3.7-5.0-3.4-4.13.9-3.93.8-5.25.0-5.05.35.6-5.6-5.6
Soleus weight1.33.95.6-2.0-1.5-2.1-2.32.3-2.32.4-1.71.7-1.71.91.9-1.8-1.8
Tibialis anterior weight3.512.220.3-2.7-3.8-2.4-2.32.1-2.12.0-4.23.8-3.84.34.4-4.5-4.4
Tibia length0.10.40.9-0.5-0.2-0.1-0.90.8-0.90.8-0.50.2-0.20.40.3-0.7-0.9
Number of licking bursts1.21.42.91.11.01.21.7-1.71.7-1.71.0-0.90.9-0.9-0.60.60.8
Food consumed during 24 hour testing period0.30.40.9-0.80.7-0.80.1-0.10.1-0.00.8-0.90.9-0.6-0.80.30.1
Times rat made contact with spout0.20.20.4-0.40.5-0.30.1-0.00.10.00.6-0.60.6-0.5-0.70.20.1
Mean time between licks in bursts0.10.10.4-0.40.1-0.40.10.1-0.00.10.6-0.10.1-0.60.00.30.5
Mean num. licks in bursts0.91.12.9-1.1-0.6-1.2-1.61.6-1.61.7-0.60.5-0.50.50.1-0.4-0.6
Std. dev. time between licks in bursts1.31.62.90.71.40.71.3-1.21.3-1.11.6-1.41.4-1.7-1.11.11.2
Water consumed over 24 hours0.10.10.3-0.60.4-0.50.00.10.00.10.4-0.50.5-0.4-0.50.10.0
Indifference point 0 sec1.62.63.90.91.40.71.9-1.81.8-1.92.0-1.41.4-1.9-1.61.51.5
Indifference point AUC2.32.76.31.61.11.52.4-2.52.5-2.51.0-1.11.1-0.9-1.01.11.2
Indifference point function ln k1.31.83.6-1.6-0.6-1.6-1.81.9-1.81.9-0.80.5-0.50.80.6-1.3-1.5
Indifference point function log k1.31.83.6-1.6-0.6-1.6-1.81.9-1.81.9-0.80.5-0.50.80.6-1.3-1.5
Delay discounting total patch changes 0 sec2.23.65.71.11.81.02.2-2.02.0-2.12.4-1.81.8-2.2-2.01.81.9
Delay discounting total patch changes 12 sec2.93.86.52.41.32.22.4-2.52.4-2.51.5-1.31.3-1.4-1.51.81.9
Delay discounting total patch changes 18 sec4.96.412.51.42.11.13.5-3.53.5-3.52.2-2.12.1-2.2-2.22.12.2
Delay discounting total patch changes 24 sec2.43.06.81.31.21.32.5-2.62.6-2.61.5-1.21.2-1.5-1.31.11.1
Delay discounting total patch changes 6 sec0.91.43.21.10.81.01.8-1.71.7-1.80.9-0.60.6-0.7-0.91.01.2
Delay discounting time to switch 0 sec0.81.32.4-0.1-1.2-0.3-1.31.3-1.41.2-1.31.1-1.11.31.5-0.8-0.6
Delay discounting water rate 0 sec0.40.71.30.20.80.31.0-1.01.1-1.00.9-0.80.8-0.9-1.10.50.3
Delay discounting water rate 12 sec0.50.81.70.41.20.70.7-0.80.9-0.80.9-1.11.1-0.8-1.30.70.4
Delay discounting water rate 18 sec0.00.00.20.10.10.3-0.10.0-0.00.00.0-0.10.10.1-0.40.0-0.0
Delay discounting water rate 24 sec0.10.10.4-0.0-0.20.30.2-0.30.3-0.2-0.60.1-0.10.60.1-0.5-0.5
Delay discounting water rate 6 sec0.50.72.5-0.31.2-0.40.6-0.70.7-0.60.7-1.21.2-0.6-1.60.3-0.0
Locomotor activity0.20.30.6-0.2-0.7-0.1-0.70.8-0.80.70.10.7-0.70.20.4-0.2-0.1
Locomotor testing distance0.10.20.30.1-0.60.2-0.30.4-0.50.40.50.6-0.6-0.30.10.20.3
Locomotor testing rearing0.00.10.2-0.1-0.3-0.1-0.20.4-0.30.40.30.4-0.4-0.2-0.00.00.1
Light reinforcement 13.15.710.91.72.11.43.2-3.33.2-3.32.0-2.12.1-2.0-1.91.92.0
Light reinforcement 21.21.63.11.11.11.01.6-1.71.6-1.80.9-1.11.1-0.8-0.91.31.3
Reaction time number correct0.40.51.1-0.8-0.5-0.7-0.91.0-1.01.0-0.60.4-0.40.70.2-0.6-0.7
Reaction time mean minus median0.10.10.4-0.0-0.30.0-0.20.1-0.10.1-0.60.2-0.20.70.6-0.10.0
Reaction time mean minus median AUC0.40.61.80.2-1.00.2-0.30.2-0.20.2-1.30.8-0.81.31.3-0.6-0.4
Reaction time num false alarms3.54.86.51.82.01.92.5-2.52.4-2.52.2-2.12.1-2.1-2.12.22.2
Reaction time num false alarms AUC2.23.14.41.61.41.62.0-2.11.9-2.11.6-1.51.5-1.6-1.51.91.9
Reaction time trials correct on left0.40.51.1-0.8-0.5-0.7-0.91.0-1.01.0-0.60.4-0.40.70.2-0.6-0.7
Reaction time trials on left0.30.41.0-0.7-0.4-0.5-0.91.0-0.91.0-0.50.3-0.30.60.1-0.5-0.6
Reaction time mean0.00.10.3-0.00.30.20.1-0.20.2-0.2-0.5-0.40.40.40.00.0-0.0
Reaction time mean AUC0.10.10.7-0.30.0-0.1-0.20.1-0.10.1-0.8-0.20.20.70.3-0.3-0.3
Median of all reaction times0.10.10.30.10.40.30.2-0.30.3-0.3-0.3-0.50.50.2-0.20.10.0
Reaction time omissions1.41.83.81.91.22.00.9-0.90.9-0.91.1-1.21.2-1.3-1.41.71.7
Reaction time false alarm rate2.23.25.41.71.41.72.2-2.32.1-2.31.5-1.41.4-1.6-1.31.81.8
Reaction time premature initiation rate0.10.20.6-0.10.2-0.2-0.20.2-0.20.20.7-0.20.2-0.8-0.50.70.6
Reaction time premature initiations0.20.20.5-0.7-0.0-0.7-0.70.7-0.70.70.3-0.00.0-0.3-0.30.20.1
Std. dev. reaction times0.10.10.50.3-0.20.4-0.20.1-0.10.1-0.70.1-0.10.70.6-0.1-0.0
Reaction time trials completed0.30.41.0-0.7-0.4-0.5-0.91.0-0.91.0-0.50.3-0.30.60.1-0.5-0.6
Reaction time trials AUC0.30.51.0-0.8-0.5-0.6-0.91.0-0.91.0-0.50.4-0.40.60.2-0.6-0.7
Social response proportion0.20.20.90.80.00.9-0.40.4-0.50.40.10.3-0.3-0.2-0.00.60.5
Social responses1.01.32.31.11.01.21.0-0.90.9-0.91.3-0.70.7-1.3-1.21.41.5
Social time0.70.92.31.40.61.50.1-0.1-0.0-0.11.5-0.40.4-1.5-0.71.11.1
Conditioned locomotion1.31.62.60.91.30.61.2-1.11.1-1.21.3-1.41.4-1.4-1.61.31.3
Cocaine response after cond. corrected1.41.53.51.91.11.71.3-1.41.4-1.50.3-0.90.9-0.3-0.91.21.3
Cocaine response after cond. not corrected1.11.22.81.71.01.51.1-1.21.1-1.20.4-0.80.8-0.4-0.91.21.2
Cocaine response before conditioning0.20.30.7-0.5-0.4-0.6-0.80.8-0.90.80.00.4-0.4-0.00.4-0.2-0.3
Saline control response1.11.52.20.91.30.81.3-1.41.3-1.41.4-1.31.3-1.5-1.21.00.9
Condit. Reinf. active minus inactive responses1.21.53.6-0.5-1.3-0.3-1.00.9-0.90.9-1.91.4-1.41.81.3-1.2-1.2
Condit. Reinf. active-inactive response ratio1.01.12.6-0.5-1.0-0.4-1.00.9-0.90.9-1.61.1-1.11.41.0-1.0-1.0
Condit. Reinf. active responses0.91.32.5-0.7-1.3-0.6-0.80.7-0.70.7-1.61.4-1.41.51.4-1.3-1.2
Condit. Reinf. inactive responses0.10.10.2-0.3-0.1-0.20.4-0.30.4-0.40.50.1-0.1-0.30.00.00.1
Condit. Reinf. lever presses0.20.31.41.20.31.10.2-0.30.3-0.3-0.1-0.30.30.1-0.20.50.5
Condit. Reinf. lever reinforcers received0.50.71.7-0.2-0.9-0.1-0.50.5-0.50.5-1.31.0-1.01.21.0-0.8-0.7
Pavlov. Cond. lever latency0.81.03.3-1.7-0.8-1.8-0.70.7-0.70.7-0.60.9-0.90.60.7-1.1-1.1
Pavlov. Cond. magazine entry latency1.01.22.71.51.11.60.5-0.40.4-0.40.9-1.01.0-1.1-1.11.51.5
Pavlov. Cond. change in total contacts0.40.61.20.4-0.90.6-0.60.5-0.60.4-1.11.0-1.01.11.0-0.6-0.6
Pavlov. Cond. index score1.01.33.81.81.01.90.7-0.70.6-0.70.7-1.01.0-0.8-1.01.41.4
Pavlov. Cond. latency score1.01.33.71.81.01.90.7-0.80.7-0.80.7-1.01.0-0.8-1.01.41.4
Pavlov. Cond. lever contacts1.42.04.62.11.32.11.0-1.01.0-1.01.1-1.41.4-1.1-1.31.61.6
Pavlov. Cond. magazine entry number0.30.31.6-1.0-0.4-1.3-0.10.1-0.00.1-0.10.3-0.30.30.5-0.8-0.8
Pavlov. Cond. intertrial magazine entries0.30.41.0-0.01.0-0.20.5-0.50.5-0.40.8-0.80.8-0.7-1.00.60.5
Pavlov. Cond. lever-magazine prob. diff.0.50.62.51.40.61.60.3-0.30.2-0.30.3-0.60.6-0.4-0.61.01.1
Pavlov. Cond. response bias0.60.82.81.50.71.70.4-0.30.3-0.40.6-0.80.8-0.6-0.71.11.1
Conditioned reinforcement - actives1.61.64.8-0.3-1.4-0.6-1.01.0-1.00.9-2.21.4-1.42.01.4-0.9-0.7
Conditioned reinforcement - inactives0.00.00.20.4-0.10.0-0.1-0.0-0.2-0.0-0.20.1-0.10.10.40.30.3
Conditioned locomotion2.22.73.6-1.4-1.7-1.9-1.71.7-1.81.7-1.91.7-1.71.71.6-1.2-1.1
Intermittent access intake day 1-15 change0.10.10.6-0.1-0.30.2-0.10.1-0.10.1-0.80.3-0.30.70.2-0.3-0.3
Intermittent access intake escalation0.10.10.50.1-0.20.40.2-0.20.3-0.2-0.70.2-0.20.60.1-0.3-0.3
Intermittent access intake escalation 20.10.10.4-0.40.2-0.30.3-0.40.4-0.4-0.6-0.20.20.6-0.1-0.3-0.3
Intermitt. access day 1 inactive lever presses1.92.14.9-2.0-1.1-2.2-1.61.4-1.61.4-0.71.1-1.11.11.6-1.2-1.3
Intermitt. access day 15 inactive lever presses0.10.10.20.00.4-0.1-0.10.0-0.10.1-0.1-0.40.40.3-0.30.40.3
Intermitt. access escalation Index4.33.87.2-2.7-2.1-2.7-1.71.8-1.81.7-1.32.1-2.11.22.0-1.7-1.6
Intermittent access day 1 total infusions0.30.31.21.1-0.01.00.6-0.70.6-0.8-0.5-0.00.00.30.10.30.3
Intermittent access day 15 total infusions0.20.21.10.5-0.30.60.4-0.50.4-0.5-1.00.3-0.30.80.20.10.2
Intermittent access terminal intake (last 3 days)0.70.83.00.3-1.10.3-0.1-0.0-0.1-0.1-1.71.0-1.01.61.0-0.6-0.5
Intermittent access total infusions0.50.62.90.4-0.70.40.3-0.40.3-0.5-1.70.6-0.61.50.8-0.5-0.4
Intermittent access day 1 locomotion0.20.20.50.70.20.60.5-0.50.5-0.6-0.1-0.30.3-0.1-0.00.30.3
Intermittent access day 15 total locomotion0.10.10.4-0.3-0.2-0.1-0.10.1-0.10.1-0.60.2-0.20.60.2-0.3-0.3
Intermittent access total locomotion0.30.31.50.0-0.50.0-0.1-0.0-0.0-0.0-1.20.5-0.51.20.7-0.5-0.4
Intermittent access standard deviation0.50.50.90.00.9-0.10.8-0.80.8-0.7-0.0-0.90.9-0.1-1.00.70.7
Cocaine induced anxiety3.94.45.7-2.4-2.0-2.3-2.22.3-2.32.3-2.11.9-1.91.82.0-1.9-1.9
Post-drug Anxiety5.15.67.4-2.7-2.4-2.5-2.32.2-2.22.2-2.22.3-2.32.22.3-2.5-2.6
Baseline Anxiety0.91.01.81.10.81.31.1-1.21.2-1.20.9-0.80.8-0.6-1.00.70.5
Lifetime Intake0.30.31.40.6-0.60.50.2-0.30.3-0.4-1.20.5-0.51.00.7-0.3-0.2
Incentive Sensitization - Responses1.01.02.1-1.2-1.0-1.1-0.70.6-0.70.6-1.51.1-1.11.20.7-1.0-1.2
Incentive Sensitization - Breakpoint1.51.52.8-1.5-1.2-1.5-0.90.8-0.90.8-1.71.3-1.31.40.9-1.2-1.4
Progressive ratio test 1 active lever presses1.11.13.41.80.41.81.1-1.21.1-1.30.2-0.40.4-0.1-0.51.01.2
Progressive ratio test 1 breakpoint0.90.92.81.70.31.71.0-1.11.0-1.10.2-0.40.4-0.1-0.40.91.1
Progressive ratio test 1 inactive lever presses0.30.31.41.2-0.11.00.3-0.50.3-0.5-0.50.1-0.10.70.30.40.4
Progressive ratio test 2 active lever presses0.60.61.80.0-1.00.0-0.30.2-0.30.1-1.41.0-1.01.30.9-0.6-0.6
Progressive ratio test 2 breakpoint0.70.82.2-0.2-1.1-0.3-0.50.3-0.50.3-1.51.1-1.11.41.0-0.7-0.7
Progressive ratio test 2 inactive lever presses0.30.42.10.4-0.30.4-0.0-0.20.1-0.2-1.40.3-0.31.40.5-0.3-0.3
Total sessions with >9 infusions0.80.91.90.0-1.2-0.1-0.50.5-0.50.4-1.41.2-1.21.01.3-1.1-1.0
Short access day 1 total inactive lever presses1.51.73.80.1-1.5-0.1-1.31.2-1.31.2-1.61.4-1.41.71.9-1.1-1.0
Short access day 10 total inactive lever presses1.41.64.9-1.9-0.6-2.2-1.31.2-1.21.2-0.80.6-0.61.21.1-1.2-1.4
Short access day 1 total infusions0.50.51.11.0-0.91.1-0.70.7-0.80.6-0.20.8-0.80.20.6-0.1-0.1
Short access day 10 total infusions0.70.72.81.70.21.41.0-1.11.0-1.1-0.2-0.30.30.1-0.20.60.7
Short access total infusions0.20.31.41.2-0.11.20.4-0.50.4-0.5-0.30.0-0.00.00.10.10.2
Short access day 1 locomotion0.10.10.30.50.10.20.0-0.0-0.0-0.0-0.1-0.10.1-0.1-0.30.40.4
Short access day 10 total locomotion0.60.71.71.30.71.30.7-0.80.7-0.80.5-0.80.8-0.6-0.50.80.8
Short access total locomotion0.80.82.91.70.61.50.9-0.90.9-1.00.2-0.70.7-0.5-0.50.80.9
Compulsive drug intake1.31.35.4-2.2-0.7-2.3-0.80.8-0.80.7-0.50.7-0.70.40.6-1.1-1.3
One hour access (0.3 mA shock)2.42.86.2-1.0-1.9-0.9-1.21.1-1.11.0-2.51.8-1.82.31.8-2.0-2.0
One hour access (shock baseline)2.93.37.1-0.0-2.20.2-1.51.4-1.41.4-2.62.1-2.12.72.2-1.8-1.7
Number of responses in last shaping day0.70.82.91.70.61.50.2-0.20.2-0.20.2-0.60.6-0.5-0.71.31.3
Context. condit. distance diff. score0.20.31.6-1.3-0.2-1.2-0.40.5-0.40.5-0.10.1-0.10.1-0.1-0.3-0.5
Locomotion velocity, session 15.86.28.81.62.71.42.5-2.32.5-2.33.0-2.72.7-2.8-2.52.62.8
Locomotion distance, session 14.65.97.42.12.42.02.7-2.62.7-2.62.4-2.42.4-2.2-2.42.52.6
Locomotion velocity, session 24.85.77.91.42.71.22.5-2.42.5-2.32.6-2.82.8-2.6-2.42.32.3
Locomotion distance, session 24.86.88.72.52.52.32.9-2.92.9-2.92.2-2.62.6-2.3-2.42.62.7
Locomotion velocity, session 34.04.66.21.72.41.42.1-2.02.1-1.92.1-2.52.5-2.0-2.32.32.3
Locomotion distance, session 33.94.27.10.62.50.41.9-1.81.9-1.72.3-2.52.5-2.2-2.72.12.0
Stereotopy head waving bouts, day 30.91.11.6-1.3-1.1-1.1-0.70.8-0.70.7-1.01.2-1.21.01.2-1.3-1.2
Stereotopy head waving duration, day 30.40.50.8-0.7-0.7-0.6-0.70.8-0.70.7-0.70.8-0.80.70.9-0.8-0.7
Locomotion velocity, session 70.10.10.40.10.00.20.2-0.20.1-0.20.2-0.00.0-0.2-0.10.50.6
Locomotion distance, session 70.81.02.30.91.00.90.7-0.60.6-0.60.9-1.01.0-1.1-1.11.51.5
Stereotopy head waving bouts, day 70.91.01.9-1.0-1.2-1.0-0.60.5-0.60.5-0.91.2-1.21.11.4-1.2-1.2
Stereotopy head waving duration, day 72.53.14.4-1.7-1.9-1.8-1.51.4-1.41.4-1.61.9-1.91.82.1-2.0-1.9
Locomotion velocity, session 80.00.00.1-0.10.1-0.20.3-0.30.4-0.20.2-0.20.2-0.2-0.10.10.2
Locomotion distance, session 82.53.86.20.72.10.62.0-1.92.0-1.82.0-2.22.2-2.0-2.52.22.1
Degree of sensitization distance1.11.12.00.0-1.40.3-1.01.0-1.10.9-1.21.4-1.41.11.4-0.8-0.7
Degree of sensitization stereotypy1.51.72.7-1.3-1.4-1.4-0.90.8-0.90.8-1.21.4-1.41.41.6-1.5-1.5
Condit. Reinf. active minus inactive responses1.21.31.71.11.21.01.1-1.11.1-1.11.3-1.31.3-1.3-1.11.11.0
Condit. Reinf. active-inactive response ratio0.60.61.00.81.00.60.6-0.70.6-0.70.8-1.01.0-0.8-0.80.80.6
Condit. Reinf. active responses2.93.64.31.72.01.61.8-1.81.8-1.82.1-2.02.0-2.1-2.01.91.8
Condit. Reinf. inactive responses2.63.14.11.81.71.81.7-1.61.6-1.61.9-1.61.6-1.9-1.92.02.0
Incentive salience index mean0.91.11.70.71.20.61.1-1.11.1-1.11.3-1.11.1-1.3-1.00.90.8
Condit. Reinf. lever presses0.10.20.4-0.20.4-0.20.6-0.50.5-0.50.6-0.30.3-0.6-0.40.20.1
Time in familiar zone, hab. session 10.10.10.20.30.20.3-0.20.3-0.20.30.2-0.20.2-0.2-0.30.40.5
Time in novel zone, hab. session 10.40.40.7-0.3-0.7-0.3-0.1-0.0-0.0-0.1-0.70.8-0.80.80.8-0.8-0.8
Total zone transitions, hab. session 11.01.43.30.80.90.41.8-1.81.8-1.80.8-1.01.0-0.7-0.81.01.1
Total locomotion distance, hab. session 13.65.26.91.72.31.52.6-2.62.6-2.62.1-2.22.2-2.1-2.42.32.3
Locomotion velocity, hab. session 12.73.94.81.42.01.22.2-2.12.1-2.11.9-2.02.0-1.9-2.22.12.1
Time in familiar zone, hab. session 22.32.44.7-1.6-1.4-1.3-2.12.2-2.22.2-0.81.3-1.30.81.0-1.2-1.3
Time in novel zone, hab. session 21.01.02.61.10.71.01.5-1.61.6-1.60.4-0.80.8-0.4-0.30.50.6
Total zone transitions, hab. session 21.92.43.21.21.50.81.8-1.71.7-1.71.4-1.71.7-1.4-1.51.61.6
Total locomotion distance, hab. session 25.67.59.12.42.72.42.9-2.72.8-2.82.8-2.72.7-2.7-3.02.82.7
Locomotion velocity, hab. session 25.57.49.52.22.82.22.8-2.72.7-2.72.8-2.82.8-2.8-3.12.82.8
Novel to familiar place preference ratio0.00.00.10.3-0.10.10.2-0.20.2-0.20.20.1-0.1-0.1-0.20.0-0.1
Novelty place preference0.10.10.20.30.00.10.3-0.30.3-0.30.40.0-0.0-0.3-0.20.0-0.0
Time in novel zone, NPP test0.00.00.10.1-0.1-0.10.2-0.20.2-0.20.20.2-0.2-0.1-0.1-0.1-0.2
Total zone transitions, NPP test4.56.48.42.22.41.92.9-2.82.8-2.82.3-2.52.5-2.3-2.42.72.8
Total locomotion distance, NPP test9.012.414.43.23.43.13.7-3.53.6-3.53.6-3.43.4-3.6-3.73.83.8
Locomotion velocity, NPP test9.914.116.73.23.83.03.9-3.73.8-3.74.0-3.83.8-3.8-4.14.04.0
Pavlov. Cond. lever latency0.30.30.90.6-0.20.4-0.80.7-0.70.8-0.90.2-0.20.90.20.20.3
Pavlov. Cond. magazine entry latency2.73.55.5-1.6-2.3-1.3-1.81.8-1.91.7-1.52.3-2.31.52.2-2.0-2.0
Pavlov. Cond. change in total contacts0.80.92.1-1.1-1.1-0.9-0.50.4-0.40.3-0.91.0-1.00.81.1-1.4-1.4
Pavlov. Cond. index score1.41.73.2-1.4-1.6-1.1-1.00.9-1.00.9-0.81.6-1.60.81.6-1.7-1.8
Pavlov. Cond. latency score0.81.12.5-1.2-1.3-0.8-0.60.6-0.70.5-0.51.3-1.30.41.2-1.5-1.6
Pavlov. Cond. lever contacts0.20.20.8-0.9-0.3-0.60.2-0.10.1-0.10.40.3-0.3-0.40.2-0.6-0.7
Pavlov. Cond. magazine entry number1.31.72.71.01.60.51.3-1.31.4-1.20.9-1.61.6-0.9-1.51.31.4
Pavlov. Cond. intertrial magazine entries1.61.93.41.81.31.51.4-1.51.4-1.51.0-1.21.2-0.9-1.11.51.7
Pavlov. Cond. lever-magazine prob. diff.1.61.93.2-1.6-1.7-1.2-1.11.0-1.11.0-0.81.7-1.70.81.6-1.7-1.8
Pavlov. Cond. response bias1.51.82.4-1.5-1.6-1.2-1.31.3-1.41.3-0.81.5-1.50.81.5-1.5-1.5
Bone: apparent density1.42.37.6-2.7-0.7-2.8-1.61.7-1.71.8-0.70.7-0.70.70.5-1.2-1.5
Bone surface2.95.112.9-3.5-1.5-3.6-2.42.4-2.42.5-1.61.6-1.61.51.2-2.0-2.3
Bone volume2.23.711.5-3.3-1.1-3.4-1.92.0-2.02.0-1.31.2-1.21.20.8-1.7-2.0
Bone: connectivity density0.40.62.0-1.2-0.2-1.4-0.90.9-0.91.0-0.30.2-0.20.40.0-0.3-0.5
Bone: cortical apparent density0.50.62.81.6-0.11.70.7-0.70.7-0.80.20.1-0.1-0.10.00.50.7
Bone: cortical area0.50.81.9-1.4-0.5-1.1-1.00.9-1.01.0-0.70.6-0.60.70.5-1.0-1.2
Bone: cortical porosity0.40.51.0-0.60.9-0.60.2-0.10.1-0.11.0-1.01.0-1.0-0.80.50.3
Bone: cortical porosity0.91.01.8-0.01.20.00.7-0.70.7-0.71.3-1.31.3-1.3-1.20.90.7
Bone: cortical thickness0.50.91.8-0.9-0.9-0.7-1.21.2-1.31.2-0.61.0-1.00.50.6-0.6-0.7
Bone: cortical thickness1.01.22.91.60.81.70.4-0.40.3-0.41.1-0.80.8-1.1-1.21.51.5
Bone: cortical tissue density0.60.73.11.7-0.01.80.8-0.80.8-0.90.3-0.00.0-0.3-0.10.70.8
Bone: elastic displacement0.70.84.11.70.42.00.10.00.00.00.7-0.40.4-0.5-0.31.01.2
Bone: elastic work0.40.52.11.20.01.4-0.60.7-0.70.70.4-0.10.1-0.40.00.60.7
Bone: endosteal estimation0.61.46.4-2.5-0.1-2.3-0.70.7-0.60.7-0.7-0.10.10.50.1-1.4-1.7
Bone: endosteal perimeter0.61.24.6-2.1-0.2-1.9-0.60.5-0.40.6-1.10.2-0.20.80.4-1.4-1.7
Bone: final force1.42.35.3-2.3-1.0-2.2-1.71.7-1.71.8-1.10.9-0.90.90.6-1.4-1.7
Bone: final moment1.82.97.0-2.6-1.1-2.4-1.91.9-1.92.0-1.21.0-1.01.00.8-1.7-2.0
Bone: marrow area0.71.46.4-2.5-0.1-2.3-0.70.7-0.60.7-0.7-0.00.00.50.2-1.4-1.7
Bone: maximum diameter0.10.31.2-1.1-0.1-0.8-0.1-0.0-0.10.0-0.50.0-0.00.40.3-0.7-0.9
Bone: maximum force1.52.65.7-2.4-1.1-2.3-1.61.6-1.61.6-1.41.0-1.01.20.9-1.7-2.0
Bone: maximum moment1.83.17.3-2.7-1.2-2.5-1.81.8-1.81.8-1.41.1-1.11.20.9-1.9-2.2
Bone: minimum diameter0.81.64.0-2.0-0.8-1.6-1.31.2-1.21.2-1.00.6-0.60.90.9-1.5-1.8
Bone: periosteal estimation0.91.86.9-2.6-0.5-2.3-1.21.1-1.11.2-0.90.4-0.40.70.4-1.5-1.9
Bone: periosteal perimeter0.91.53.4-1.7-0.8-1.3-1.10.9-1.01.0-1.50.8-0.81.31.0-1.6-1.8
Bone: post-yield work0.81.03.8-1.9-0.5-1.9-0.90.8-0.80.8-0.80.3-0.30.50.2-1.1-1.3
Bone: stiffness1.93.09.9-3.1-1.1-3.2-1.31.3-1.31.3-1.51.0-1.01.20.7-1.9-2.2
Bone: tissue strength1.31.32.4-1.0-1.1-0.9-0.80.7-0.70.7-1.41.0-1.01.41.5-1.6-1.5
Bone: trabecular number0.30.53.1-1.60.3-1.8-0.50.6-0.50.60.2-0.30.3-0.3-0.5-0.1-0.3
Bone: trabecular spacing0.30.30.80.8-0.60.80.1-0.20.1-0.3-0.80.6-0.60.90.6-0.4-0.4
Bone: trabecular thickness0.20.20.5-0.40.6-0.50.3-0.20.3-0.20.5-0.70.7-0.4-0.70.40.4
Bone: trabecular tissue density0.30.41.20.70.00.80.9-1.11.0-1.10.1-0.20.2-0.1-0.20.20.3
Breakpoint value in progressive ratio session1.11.22.6-0.2-0.90.1-0.90.8-0.80.8-1.50.9-0.91.51.4-1.6-1.6
Distance traveled before self-admin0.60.61.1-0.8-0.6-1.1-0.80.8-0.80.8-1.10.7-0.71.10.6-0.6-0.5
Distance traveled after self-admin1.51.73.50.4-1.20.5-1.81.7-1.91.7-1.11.3-1.31.31.0-0.7-0.7
Delta time in closed arm before/after self-admin0.10.10.30.3-0.20.60.1-0.10.0-0.10.20.2-0.2-0.10.1-0.1-0.2
Delta time in open arm before/after self-admin2.22.13.41.31.81.21.1-1.21.1-1.11.2-1.81.8-1.2-1.41.81.8
Diff in mean of infusions in LGA sessions0.20.20.4-0.3-0.4-0.2-0.70.7-0.70.6-0.40.4-0.40.50.4-0.4-0.4
Extinction: sum of active levers before priming0.40.41.7-1.1-0.1-1.0-0.30.2-0.10.3-0.20.1-0.10.70.5-1.2-1.3
Active lever presses in extinction session 60.10.10.30.2-0.00.40.1-0.10.2-0.1-0.50.1-0.10.50.2-0.5-0.5
Delta distance traveled before/after self-admin0.90.93.11.40.91.80.2-0.20.1-0.21.3-0.90.9-1.2-0.91.00.8
Delta ambulatory time before/after self-admin0.60.62.11.20.71.4-0.0-0.0-0.1-0.01.0-0.80.8-0.9-0.80.90.6
Time in closed arm before self-admin0.40.53.2-1.60.1-1.80.4-0.30.3-0.30.5-0.20.2-0.50.1-0.1-0.0
Time in closed arm after self-admin0.50.51.1-0.6-1.0-0.40.0-0.10.0-0.1-0.61.0-1.00.71.1-0.9-0.8
Time in open arm before self-admin2.93.04.7-0.4-2.2-0.6-1.61.5-1.61.5-2.02.2-2.22.11.9-1.8-1.7
Time in open arm after self-admin0.30.30.70.70.80.6-0.0-0.0-0.0-0.00.5-0.80.8-0.4-0.70.70.7
Sum of active levers in priming session hrs 5-60.70.72.00.5-0.80.3-0.60.5-0.60.5-1.10.8-0.81.41.3-0.8-0.7
Time to tail flick, vehicle, before self-admin0.10.10.3-0.1-0.5-0.6-0.10.1-0.10.1-0.40.4-0.40.50.4-0.2-0.1
Time to tail flick, vehicle, after self-admin0.10.10.4-0.60.4-0.60.3-0.30.4-0.2-0.0-0.40.4-0.1-0.2-0.2-0.3
Time to tail flick, test, before self-admin0.20.20.50.20.2-0.10.5-0.60.5-0.60.3-0.20.2-0.1-0.30.70.7
Time to tail flick, test, after self-admin2.52.64.1-1.9-1.4-1.9-2.02.0-2.02.0-0.71.5-1.50.91.2-1.2-1.4
Delta time to tail flick, vehicle, before/after SA0.20.20.6-0.30.8-0.00.3-0.30.4-0.30.1-0.60.6-0.4-0.7-0.1-0.2
Delta time to tail flick, test, before/after SA1.91.73.1-1.5-0.9-1.4-1.71.8-1.71.8-0.41.0-1.00.41.0-1.2-1.4
Ambulatory time before self-admin0.60.61.2-0.8-0.7-1.1-0.50.5-0.50.5-0.90.8-0.81.00.8-0.7-0.6
Ambulatory time after self-admin1.51.63.5-0.3-1.0-0.4-1.81.7-1.91.7-1.11.2-1.21.21.1-0.9-1.0
Total heroin consumption0.30.41.2-0.5-0.1-0.2-0.60.6-0.50.7-1.00.2-0.20.80.4-0.9-1.1
Area under the delay curve0.80.91.6-0.3-1.1-0.1-1.01.0-1.01.0-1.31.0-1.01.10.9-0.8-0.8
Delay disc. indifference point, 0s delay0.20.20.40.5-0.60.5-0.30.3-0.30.3-0.60.6-0.60.60.5-0.2-0.2
Delay disc. indifference point, 16s delay0.50.60.9-0.4-1.0-0.2-0.80.8-0.80.8-0.90.9-0.90.70.7-0.7-0.7
Delay disc. indifference point, 2s delay4.14.66.9-1.3-2.6-1.0-1.81.8-1.81.7-2.42.6-2.62.52.5-2.3-2.2
Delay disc. indifference point, 24s delay0.40.40.9-0.1-0.60.2-0.70.7-0.70.7-0.90.5-0.50.70.5-0.5-0.5
Delay disc. indifference point, 4s delay1.01.01.8-0.4-1.1-0.1-1.11.1-1.01.1-1.31.1-1.11.40.9-0.9-0.9
Delay disc. indifference point, 8s delay0.30.30.6-0.5-0.6-0.5-0.70.7-0.70.8-0.60.7-0.70.40.3-0.3-0.4
Delay discount exponential model param1.41.52.30.51.30.31.3-1.41.3-1.41.5-1.31.3-1.4-1.11.11.0
Delay discount hyperbolic model param1.81.93.00.61.50.31.4-1.41.4-1.41.7-1.51.5-1.6-1.41.31.2
Fecal boli incidents, locomotor time 12.93.14.51.42.01.71.5-1.41.4-1.41.6-2.12.1-1.7-2.02.02.0
Change in fecal boli incidents, locomotor task0.60.61.5-0.5-0.7-1.2-0.50.5-0.40.5-0.60.8-0.80.70.9-1.0-1.0
Time >=10cm from walls, locomotor time 10.80.81.71.30.71.20.9-0.90.9-0.90.9-0.70.7-0.8-0.90.90.8
Bouts of movement, locomotor time 10.60.61.10.90.60.90.9-0.80.8-0.80.7-0.60.6-0.7-0.81.01.0
Total resting periods, locomotor time 11.61.72.41.51.11.51.3-1.31.3-1.31.4-1.11.1-1.2-1.21.51.5
Rest time, locomotor task time 10.10.10.30.20.3-0.00.4-0.30.3-0.30.5-0.30.3-0.4-0.30.40.5
Distance moved, locomotor task time 10.40.41.00.5-0.90.9-0.30.3-0.30.3-0.60.9-0.90.61.0-0.6-0.6
Vertical activity count, locomotor time 12.22.33.4-1.1-1.8-0.9-1.41.4-1.51.3-1.81.8-1.81.61.8-1.3-1.3
Time >=10cm from walls, locomotor time 20.10.10.40.6-0.50.5-0.10.1-0.10.10.20.5-0.5-0.00.00.10.1
Bouts of movement, locomotor time 21.51.72.3-1.5-1.5-1.0-0.91.0-1.01.0-1.31.5-1.51.51.4-1.4-1.3
Total resting periods, locomotor time 21.51.62.3-1.4-1.5-0.9-0.80.8-0.80.8-1.41.5-1.51.51.4-1.4-1.3
Rest time, locomotor task time 20.60.71.4-0.10.90.11.2-1.11.1-1.20.7-0.80.8-0.8-0.90.80.9
Distance moved, locomotor task time 20.20.30.80.9-0.70.9-0.50.5-0.40.5-0.00.6-0.60.10.4-0.2-0.2
Vertical activity count, locomotor time 21.41.62.4-0.2-1.6-0.1-1.41.5-1.51.5-1.31.5-1.51.11.2-0.9-0.9
Weight adjusted by age0.50.63.01.60.31.70.2-0.30.3-0.30.5-0.30.3-0.6-0.50.70.8
Seeking ratio, delayed vs. immediate footshock0.40.51.51.1-0.81.2-0.60.6-0.70.6-0.10.7-0.70.20.6-0.1-0.0
Locomotion in novel chamber3.64.56.5-1.2-2.6-1.0-2.32.4-2.42.4-1.62.5-2.51.72.3-2.0-2.0
Locomotion in novel chamber post-restriction2.42.94.4-1.1-2.1-1.1-1.92.0-2.12.0-1.02.1-2.10.91.8-1.4-1.4
Progressive ratio0.20.20.90.9-0.30.70.2-0.20.2-0.1-0.70.3-0.30.60.5-0.3-0.2
Food seeking constrained by brief footshock0.81.03.31.80.31.61.2-1.41.3-1.40.5-0.30.3-0.7-0.10.50.5
Seeking ratio, punishment vs. effort0.10.10.30.00.20.10.0-0.10.0-0.20.5-0.10.1-0.6-0.10.30.2
Run reversals in cocaine runway, females0.40.41.0-0.7-0.4-1.0-0.70.6-0.60.7-0.30.3-0.30.30.7-0.6-0.7
Run reversals in cocaine runway, males0.10.10.40.6-0.30.6-0.10.1-0.1-0.0-0.40.3-0.30.50.5-0.2-0.1
Latency to leave start box in cocaine runway0.10.20.5-0.1-0.70.2-0.30.3-0.40.2-0.00.7-0.7-0.00.6-0.2-0.2
Latency to leave start box in cocaine runway, F0.40.40.80.80.20.90.8-0.80.7-0.90.5-0.30.3-0.6-0.20.50.6
Latency to leave start box in cocaine runway, M2.42.33.6-1.5-1.7-1.1-1.81.8-1.91.8-1.01.8-1.80.91.5-1.2-1.3
Cd content in liver0.20.30.90.8-0.50.9-0.30.2-0.20.2-0.70.5-0.50.60.7-0.3-0.2
Co content in liver0.30.40.9-0.7-0.5-0.7-0.40.4-0.30.5-0.50.5-0.50.60.6-0.9-0.9
Cu content in liver4.55.58.4-2.2-2.3-1.9-2.22.1-2.12.1-2.52.3-2.32.42.3-2.8-2.9
Fe content in liver0.10.10.50.7-0.10.70.4-0.40.4-0.40.2-0.10.1-0.10.10.20.4
K content in liver0.30.30.5-0.60.5-0.70.6-0.50.6-0.40.6-0.60.6-0.7-0.60.10.1
Mg content in liver0.30.30.5-0.40.5-0.40.7-0.60.7-0.50.7-0.50.5-0.7-0.60.20.3
Mn content in liver0.20.20.9-0.8-0.3-1.0-0.40.5-0.50.50.10.4-0.4-0.10.2-0.1-0.1
Na content in liver0.50.53.7-1.5-0.5-1.9-0.10.2-0.20.2-0.40.3-0.30.40.3-0.5-0.5
Rb content in liver0.20.20.60.2-0.50.4-0.30.3-0.20.3-0.60.6-0.60.60.4-0.8-0.8
Se content in liver0.10.10.40.50.10.10.1-0.10.1-0.10.1-0.00.00.0-0.30.50.6
Sr content in liver1.00.92.3-0.31.1-0.30.6-0.50.5-0.41.5-1.01.0-1.5-1.31.00.8
Zn content in liver3.53.94.82.01.82.02.0-1.91.9-1.92.2-1.91.9-2.2-1.92.01.9