Hub : Genes

Iqck

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000036758 0.38 0.11 0.0e+00 0.22 0.26 0.28 0.28 1.9e-24 3.3e-29 1.1e-31 1.0e-31
2 BLA gene expression ENSRNOG00000036758 0.18 0.08 7.4e-06 0.07 0.1 0.08 0.1 1.6e-04 4.8e-06 4.7e-05 8.7e-06
3 Brain gene expression ENSRNOG00000036758 0.14 0.07 9.3e-09 0.08 0.1 0.09 0.09 1.1e-07 2.2e-09 7.9e-09 2.4e-08
4 Brain mRNA stability ENSRNOG00000036758 0.03 0.02 7.2e-03 0.03 0.02 -0 0.02 1.6e-03 4.3e-03 4.7e-01 7.2e-03
5 IL gene expression ENSRNOG00000036758 0.36 0.15 7.3e-04 -0.01 0.06 0.04 0.01 7.4e-01 1.8e-02 3.7e-02 1.5e-01
6 LHb gene expression ENSRNOG00000036758 0.48 0.16 5.6e-05 0.07 0.16 0.13 0.13 8.1e-03 1.3e-04 5.4e-04 5.8e-04
7 NAcc gene expression ENSRNOG00000036758 0.13 0.07 3.7e-05 0.04 0.06 0.06 0.05 1.0e-03 3.0e-05 2.1e-05 9.0e-05
8 NAcc intron excision ratio chr1:173217154:173220756 0.06 0.04 1.1e-03 0.02 0.03 0.03 0.03 7.8e-03 5.6e-03 1.8e-03 3.0e-03
9 OFC gene expression ENSRNOG00000036758 0.36 0.16 8.1e-04 0.03 0.08 0.14 0.1 6.6e-02 6.0e-03 4.2e-04 2.7e-03
10 PL gene expression ENSRNOG00000036758 0.17 0.09 1.3e-06 0.01 0.08 0.05 0.07 9.9e-02 1.4e-06 1.9e-04 9.0e-06
11 PL intron excision ratio chr1:173217154:173220756 0.11 0.07 1.4e-04 0.01 0.04 0.03 0.03 7.5e-02 3.7e-04 4.0e-03 2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail1.54.89.7-3.1-0.9-2.0-2.4-0.1-2.0-3.02.4-3.0-2.1-0.6
BMI without tail3.88.119.9-4.5-1.0-2.6-3.4-0.3-2.7-3.62.9-3.7-2.5-1.0
Body weight0.93.812.4-3.5-0.1-1.8-2.70.0-1.5-2.32.1-2.1-1.2-0.5
Epididymis fat weight0.30.82.6-1.1-0.0-0.1-1.60.7-0.4-1.00.3-1.0-0.4-1.4
Glucose0.91.42.20.51.31.4-0.81.41.31.0-1.11.41.5-1.1
Heart weight1.11.62.70.81.41.6-0.81.71.61.1-1.01.21.4-0.8
Left kidney weight0.92.710.9-3.30.9-1.0-2.70.9-0.5-1.42.1-1.4-0.5-0.3
Right kidney weight1.13.112.4-3.50.9-1.2-2.90.7-0.6-1.52.2-1.6-0.5-0.3
Tail length0.72.29.7-3.10.7-1.0-2.80.5-0.7-1.01.3-1.0-0.2-0.8
Length with tail0.10.52.4-1.50.9-0.2-1.30.40.10.00.50.10.5-0.1
Length without tail0.41.02.21.00.60.71.2-0.11.01.4-0.71.51.10.8
Liver weight, left0.20.40.9-0.5-0.6-0.5-0.5-0.2-0.8-0.90.3-0.8-0.7-0.7
Liver weight, right1.93.15.6-1.1-2.0-1.90.3-1.5-2.2-2.31.4-2.4-2.30.2
Parametrial fat weight0.81.67.0-1.81.00.1-2.61.50.1-0.80.6-0.60.2-1.6
Retroperitoneal fat weight0.51.68.3-0.10.20.9-2.11.30.1-0.3-1.1-0.30.4-2.9
Intraocular pressure0.40.61.1-0.8-0.8-0.9-0.4-0.7-1.1-0.70.6-1.0-0.8-0.0
Extensor digitorum longus weight2.08.124.3-4.90.0-3.3-1.6-1.1-2.0-3.04.4-2.8-2.02.3
Soleus weight0.72.07.1-2.32.00.2-2.71.60.80.21.10.10.9-0.3
Tibialis anterior weight1.86.326.5-5.11.4-2.0-3.80.8-0.9-2.13.5-2.0-0.70.4
Tibia length0.41.31.90.71.21.3-0.71.31.31.4-0.91.21.3-0.6
Number of licking bursts2.42.88.72.70.10.83.0-0.61.22.1-0.91.80.81.9
Food consumed during 24 hour testing period0.50.61.8-1.40.7-0.5-1.00.50.1-0.71.3-0.5-0.20.5
Times rat made contact with spout1.11.24.4-1.50.2-1.30.0-0.5-0.4-0.22.1-0.7-0.71.9
Mean time between licks in bursts0.50.61.30.0-1.1-0.70.9-0.8-0.8-0.60.6-0.9-1.10.6
Mean num. licks in bursts2.42.810.4-3.20.4-1.3-2.80.4-1.0-1.71.9-1.7-0.8-0.6
Std. dev. time between licks in bursts0.70.82.0-0.2-1.1-0.70.3-0.4-0.9-1.40.7-1.4-1.30.0
Water consumed over 24 hours1.21.46.80.2-0.3-0.92.1-1.4-0.10.51.10.4-0.32.6
Indifference point 0 sec0.81.34.8-0.20.81.0-1.91.40.50.0-1.10.40.9-2.2
Indifference point AUC0.50.51.5-0.51.20.6-1.01.20.9-0.40.20.30.6-0.2
Indifference point function ln k0.10.10.5-0.70.1-0.2-0.60.1-0.20.40.3-0.2-0.1-0.3
Indifference point function log k0.10.10.5-0.70.1-0.2-0.60.1-0.20.40.3-0.2-0.1-0.3
Delay discounting total patch changes 0 sec0.91.45.7-0.20.71.0-2.01.50.50.0-1.10.30.8-2.4
Delay discounting total patch changes 12 sec0.20.21.0-0.3-0.2-0.1-0.50.2-0.3-1.00.1-0.6-0.4-0.5
Delay discounting total patch changes 18 sec0.50.60.90.60.90.9-0.40.91.00.2-0.80.91.0-0.5
Delay discounting total patch changes 24 sec0.60.72.4-0.40.80.7-1.61.20.5-0.0-0.50.20.7-1.4
Delay discounting total patch changes 6 sec3.65.58.31.62.12.9-1.72.82.41.7-2.62.22.6-2.6
Delay discounting time to switch 0 sec1.92.97.71.0-2.3-1.42.8-2.6-1.7-0.40.3-0.9-1.71.5
Delay discounting water rate 0 sec0.10.20.5-0.60.3-0.0-0.70.40.1-0.60.2-0.10.1-0.3
Delay discounting water rate 12 sec1.11.66.1-0.91.30.9-2.51.60.70.6-0.50.51.1-1.8
Delay discounting water rate 18 sec0.40.52.1-0.50.30.4-1.30.70.0-0.1-0.50.10.4-1.5
Delay discounting water rate 24 sec0.50.61.5-0.81.20.4-1.20.90.80.70.20.60.9-0.2
Delay discounting water rate 6 sec1.42.13.60.51.81.6-1.01.91.91.6-0.81.51.7-0.7
Locomotor activity0.20.30.5-0.1-0.7-0.4-0.1-0.4-0.7-0.7-0.0-0.7-0.6-0.4
Locomotor testing distance0.10.20.9-0.3-0.2-0.0-0.90.3-0.3-0.6-0.1-0.5-0.2-0.9
Locomotor testing rearing0.20.41.10.1-0.9-0.2-0.4-0.2-0.7-0.5-0.4-0.7-0.6-1.1
Light reinforcement 10.20.42.20.7-0.50.4-0.40.2-0.2-0.0-1.0-0.1-0.0-1.5
Light reinforcement 20.30.32.00.4-0.20.4-0.80.4-0.1-0.1-0.7-0.3-0.0-1.4
Reaction time number correct0.20.40.80.9-0.90.00.9-0.7-0.50.2-0.80.2-0.2-0.4
Reaction time mean minus median0.10.10.40.10.50.4-0.30.70.5-0.10.1-0.10.2-0.0
Reaction time mean minus median AUC0.40.51.20.80.41.0-0.41.00.70.4-1.00.30.5-1.1
Reaction time num false alarms0.60.92.21.30.60.61.30.11.10.9-0.11.00.71.5
Reaction time num false alarms AUC0.30.51.71.00.00.11.3-0.30.40.40.00.40.11.3
Reaction time trials correct on left0.20.40.80.9-0.90.00.9-0.7-0.50.2-0.80.2-0.2-0.4
Reaction time trials on left0.30.40.80.9-0.9-0.00.8-0.7-0.50.2-0.80.1-0.3-0.4
Reaction time mean0.20.20.7-0.40.10.0-0.80.5-0.1-0.70.1-0.6-0.2-0.6
Reaction time mean AUC0.20.20.6-0.3-0.4-0.2-0.50.0-0.4-0.80.1-0.8-0.5-0.5
Median of all reaction times0.20.30.9-0.5-0.2-0.2-0.80.2-0.4-0.90.3-0.9-0.5-0.6
Reaction time omissions0.81.12.70.2-1.6-0.90.9-1.2-1.4-1.00.1-1.2-1.4-0.1
Reaction time false alarm rate0.30.42.70.40.5-0.00.9-0.10.60.30.60.30.21.6
Reaction time premature initiation rate0.81.03.1-1.80.1-1.3-0.4-0.6-0.7-0.41.6-0.8-0.61.2
Reaction time premature initiations0.60.91.7-1.1-0.5-1.30.3-1.1-1.0-0.21.1-0.7-0.81.1
Std. dev. reaction times0.10.20.7-0.20.40.3-0.80.70.2-0.2-0.1-0.30.1-0.7
Reaction time trials completed0.30.40.80.9-0.9-0.00.8-0.7-0.50.2-0.80.1-0.3-0.4
Reaction time trials AUC0.20.30.60.7-0.8-0.00.7-0.6-0.50.2-0.80.1-0.2-0.4
Social response proportion0.40.42.00.7-0.20.7-0.30.50.1-0.5-1.10.00.1-1.4
Social responses0.30.41.01.0-1.00.20.7-0.3-0.4-0.7-0.8-0.3-0.5-0.6
Social time0.60.82.31.40.01.00.60.20.60.6-1.51.10.7-0.6
Conditioned locomotion1.11.32.80.0-1.4-1.21.6-1.7-1.2-0.70.7-0.7-1.21.1
Cocaine response after cond. corrected0.10.20.40.60.20.30.50.10.40.6-0.30.40.30.3
Cocaine response after cond. not corrected0.10.10.2-0.3-0.0-0.40.1-0.2-0.20.20.4-0.2-0.20.5
Cocaine response before conditioning1.21.54.9-2.2-0.3-1.6-0.8-0.7-1.2-0.91.7-1.2-1.00.7
Saline control response0.10.20.50.6-0.00.5-0.20.40.20.1-0.60.10.2-0.7
Condit. Reinf. active minus inactive responses0.60.73.8-0.1-0.10.5-1.40.9-0.1-0.5-0.5-0.6-0.2-1.9
Condit. Reinf. active-inactive response ratio0.70.73.60.70.00.9-1.01.10.30.1-1.0-0.20.2-1.9
Condit. Reinf. active responses0.30.41.8-0.5-0.30.0-1.00.5-0.4-0.7-0.1-0.7-0.4-1.3
Condit. Reinf. inactive responses0.91.22.9-1.7-0.5-1.3-0.2-0.9-1.1-1.21.4-1.0-0.90.7
Condit. Reinf. lever presses0.70.91.9-1.4-0.4-0.6-1.30.2-0.9-1.40.5-1.2-0.8-1.1
Condit. Reinf. lever reinforcers received0.30.41.9-0.2-0.50.1-0.80.3-0.5-0.7-0.3-0.7-0.5-1.4
Pavlov. Cond. lever latency0.40.51.61.30.00.31.1-0.30.40.9-0.50.80.40.7
Pavlov. Cond. magazine entry latency1.01.13.90.6-1.3-0.82.0-1.5-0.8-0.20.3-0.3-0.91.2
Pavlov. Cond. change in total contacts0.81.13.70.50.51.2-1.11.20.70.3-1.40.50.8-1.9
Pavlov. Cond. index score0.10.10.3-0.0-0.6-0.20.3-0.3-0.4-0.4-0.0-0.4-0.5-0.2
Pavlov. Cond. latency score0.10.20.3-0.2-0.6-0.40.3-0.4-0.5-0.50.2-0.4-0.50.0
Pavlov. Cond. lever contacts0.60.82.0-1.4-0.5-0.7-1.10.0-0.9-1.20.7-1.2-0.8-0.8
Pavlov. Cond. magazine entry number0.50.62.3-1.50.6-0.4-1.50.5-0.1-0.60.9-0.6-0.1-0.1
Pavlov. Cond. intertrial magazine entries1.31.74.0-2.0-0.4-1.1-1.60.0-1.1-1.71.2-1.8-1.2-0.6
Pavlov. Cond. lever-magazine prob. diff.0.20.20.60.1-0.8-0.30.5-0.5-0.6-0.5-0.0-0.4-0.6-0.1
Pavlov. Cond. response bias0.20.20.5-0.4-0.6-0.3-0.2-0.1-0.6-0.60.1-0.7-0.6-0.6
Conditioned reinforcement - actives1.91.93.6-0.21.91.4-1.01.61.61.5-0.51.51.9-0.9
Conditioned reinforcement - inactives1.71.93.40.81.61.60.41.31.81.8-0.91.71.8-0.1
Conditioned locomotion0.10.20.40.20.40.4-0.00.10.40.7-0.30.60.6-0.1
Intermittent access intake day 1-15 change0.90.93.11.00.50.31.8-0.00.90.90.20.90.51.7
Intermittent access intake escalation0.80.82.30.90.70.51.50.21.00.90.10.90.61.4
Intermittent access intake escalation 20.90.92.81.10.50.41.70.00.90.80.20.90.51.6
Intermitt. access day 1 inactive lever presses0.60.61.20.51.00.70.20.71.11.0-0.11.01.00.3
Intermitt. access day 15 inactive lever presses0.30.31.2-1.10.3-0.6-0.0-0.2-0.1-0.21.0-0.3-0.20.8
Intermitt. access escalation Index0.30.30.6-0.6-0.0-0.3-0.60.3-0.2-0.80.7-0.8-0.5-0.0
Intermittent access day 1 total infusions0.70.83.5-1.20.20.1-1.90.7-0.3-0.4-0.3-0.40.1-1.8
Intermittent access day 15 total infusions0.30.30.7-0.10.70.6-0.40.80.60.5-0.40.40.6-0.6
Intermittent access terminal intake (last 3 days)0.30.30.8-0.10.70.7-0.60.90.60.4-0.40.40.6-0.7
Intermittent access total infusions0.60.62.1-0.90.60.5-1.50.90.20.1-0.30.00.5-1.5
Intermittent access day 1 locomotion0.80.93.5-0.80.40.5-1.91.00.0-0.2-0.5-0.30.3-1.9
Intermittent access day 15 total locomotion3.43.66.51.81.52.6-0.42.22.11.8-2.21.82.0-2.0
Intermittent access total locomotion1.21.45.70.10.61.3-1.71.70.60.1-1.10.10.6-2.4
Intermittent access standard deviation0.30.30.8-0.20.90.20.20.50.70.50.40.50.60.7
Cocaine induced anxiety0.10.10.40.7-0.20.20.40.20.1-0.3-0.1-0.3-0.30.0
Post-drug Anxiety1.01.11.90.91.01.4-0.31.21.31.1-1.01.11.2-0.9
Baseline Anxiety1.11.22.6-0.71.60.8-1.11.11.11.2-0.21.21.6-0.6
Lifetime Intake0.80.93.5-1.40.60.3-1.90.9-0.0-0.2-0.0-0.20.4-1.6
Incentive Sensitization - Responses0.30.30.7-0.5-0.8-0.4-0.3-0.6-0.8-0.4-0.1-0.4-0.5-0.6
Incentive Sensitization - Breakpoint0.20.20.6-0.4-0.7-0.3-0.4-0.4-0.8-0.4-0.2-0.4-0.4-0.7
Progressive ratio test 1 active lever presses0.30.31.5-0.6-0.10.1-1.00.5-0.3-0.4-0.3-0.4-0.1-1.2
Progressive ratio test 1 breakpoint0.30.31.4-0.6-0.10.1-1.00.4-0.3-0.3-0.3-0.4-0.1-1.2
Progressive ratio test 1 inactive lever presses0.20.20.6-0.80.1-0.0-0.70.4-0.0-0.30.2-0.4-0.1-0.5
Progressive ratio test 2 active lever presses0.30.41.9-0.60.10.3-1.10.4-0.10.0-0.5-0.00.2-1.4
Progressive ratio test 2 breakpoint0.30.42.1-0.50.00.3-1.10.4-0.2-0.0-0.5-0.10.2-1.5
Progressive ratio test 2 inactive lever presses0.30.41.8-0.10.20.6-0.80.70.20.2-0.70.10.3-1.3
Total sessions with >9 infusions1.41.68.0-2.80.8-0.8-2.20.5-0.4-0.61.4-0.70.1-0.5
Short access day 1 total inactive lever presses0.40.40.7-0.20.70.6-0.60.70.60.8-0.60.70.9-0.8
Short access day 10 total inactive lever presses1.11.22.31.21.01.10.90.61.41.5-0.61.51.30.5
Short access day 1 total infusions0.90.93.4-1.41.00.4-1.81.00.30.5-0.00.30.9-1.4
Short access day 10 total infusions0.50.62.9-1.70.3-0.4-1.30.3-0.4-0.40.6-0.5-0.1-0.6
Short access total infusions1.21.35.6-1.90.70.1-2.41.0-0.1-0.20.2-0.30.4-1.8
Short access day 1 locomotion0.50.51.0-0.50.90.5-0.80.70.60.8-0.20.71.0-0.7
Short access day 10 total locomotion1.01.12.4-1.3-0.4-0.5-1.60.4-0.8-1.40.7-1.4-1.0-0.9
Short access total locomotion1.81.97.1-1.00.90.9-2.71.70.4-0.0-0.6-0.10.7-2.6
Compulsive drug intake0.80.81.7-0.2-1.1-0.5-0.9-0.3-1.1-1.30.0-1.3-1.1-0.9
One hour access (0.3 mA shock)1.01.13.7-1.4-0.1-0.1-1.90.8-0.5-1.20.4-1.2-0.6-1.5
One hour access (shock baseline)0.70.81.20.51.01.1-0.11.11.11.0-0.80.91.0-0.6
Number of responses in last shaping day0.20.21.1-1.0-0.0-0.5-0.8-0.2-0.5-0.30.4-0.3-0.1-0.2
Context. condit. distance diff. score0.10.20.40.7-0.60.10.4-0.3-0.30.4-0.7-0.0-0.2-0.5
Locomotion velocity, session 10.20.20.5-0.20.70.20.10.30.60.30.00.70.60.4
Locomotion distance, session 10.40.51.6-1.10.1-0.3-1.30.3-0.4-0.70.2-0.7-0.3-0.9
Locomotion velocity, session 20.30.40.90.20.80.50.20.30.80.7-0.31.00.90.3
Locomotion distance, session 20.50.83.1-1.80.5-0.6-1.30.3-0.3-1.11.0-0.7-0.20.0
Locomotion velocity, session 30.10.10.7-0.80.0-0.4-0.6-0.1-0.4-0.20.3-0.3-0.1-0.2
Locomotion distance, session 31.11.22.0-1.1-0.7-1.40.6-1.2-1.0-1.01.3-0.8-1.01.4
Stereotopy head waving bouts, day 30.50.61.31.00.10.80.00.40.51.2-1.10.70.6-0.8
Stereotopy head waving duration, day 30.50.61.30.80.20.9-0.30.50.41.0-1.20.60.6-1.1
Locomotion velocity, session 72.42.64.4-2.0-1.0-2.10.1-1.6-1.8-1.91.9-1.5-1.51.2
Locomotion distance, session 70.91.12.8-0.7-0.7-1.30.9-1.3-0.8-1.11.3-0.6-0.91.7
Stereotopy head waving bouts, day 70.20.20.8-0.40.30.2-0.90.4-0.00.3-0.30.10.3-0.9
Stereotopy head waving duration, day 70.70.82.3-1.5-0.2-0.7-1.30.1-0.9-0.90.6-1.1-0.6-0.9
Locomotion velocity, session 80.10.10.2-0.10.40.2-0.30.20.20.2-0.30.40.4-0.2
Locomotion distance, session 80.10.10.3-0.6-0.2-0.4-0.4-0.1-0.4-0.50.2-0.5-0.3-0.2
Degree of sensitization distance1.11.21.91.00.91.4-0.71.21.20.9-1.21.01.2-1.1
Degree of sensitization stereotypy0.50.52.2-1.50.1-0.6-1.1-0.0-0.6-0.70.7-0.7-0.3-0.3
Condit. Reinf. active minus inactive responses0.10.10.50.5-0.40.2-0.1-0.0-0.2-0.2-0.5-0.1-0.1-0.7
Condit. Reinf. active-inactive response ratio0.40.40.90.0-1.0-0.40.0-0.5-0.9-0.9-0.1-0.8-0.8-0.6
Condit. Reinf. active responses0.10.10.40.60.00.5-0.10.40.3-0.0-0.50.20.2-0.6
Condit. Reinf. inactive responses0.20.20.50.40.60.6-0.20.70.70.2-0.30.50.5-0.2
Incentive salience index mean0.40.50.9-0.2-0.8-0.70.3-0.7-0.8-0.90.5-0.8-0.90.2
Condit. Reinf. lever presses1.01.42.1-0.2-1.4-1.21.1-1.3-1.2-1.31.1-1.2-1.51.0
Time in familiar zone, hab. session 12.52.33.81.31.61.9-0.31.71.91.6-1.41.71.8-0.7
Time in novel zone, hab. session 12.92.85.7-1.7-1.8-2.20.1-2.1-2.4-1.61.3-1.7-1.80.4
Total zone transitions, hab. session 11.01.35.2-1.71.50.3-2.31.50.6-0.40.50.00.7-0.9
Total locomotion distance, hab. session 11.82.612.2-2.51.60.1-3.51.80.3-0.60.7-0.60.5-1.6
Locomotion velocity, hab. session 11.52.210.5-2.11.30.2-3.21.80.2-0.70.6-0.80.3-1.7
Time in familiar zone, hab. session 20.20.20.5-0.40.60.2-0.70.60.4-0.20.2-0.00.3-0.0
Time in novel zone, hab. session 20.10.10.20.1-0.4-0.10.1-0.2-0.30.2-0.3-0.1-0.2-0.4
Total zone transitions, hab. session 20.81.14.4-1.61.00.1-2.11.10.2-0.70.3-0.20.4-1.2
Total locomotion distance, hab. session 21.11.56.4-1.81.50.2-2.51.40.5-0.20.5-0.10.7-1.0
Locomotion velocity, hab. session 21.11.56.5-2.11.3-0.1-2.61.30.3-0.60.8-0.40.4-0.8
Novel to familiar place preference ratio0.80.81.61.30.71.10.50.71.21.2-0.71.00.90.2
Novelty place preference1.01.12.01.30.91.10.60.71.41.4-0.71.31.10.4
Time in novel zone, NPP test1.01.01.71.30.81.20.40.81.31.3-0.81.21.00.1
Total zone transitions, NPP test0.50.72.9-1.50.8-0.1-1.70.80.1-0.50.5-0.30.2-0.6
Total locomotion distance, NPP test0.70.93.5-1.31.40.3-1.91.30.70.00.5-0.00.6-0.4
Locomotion velocity, NPP test0.60.82.9-1.21.30.3-1.71.20.70.10.50.10.7-0.3
Pavlov. Cond. lever latency5.16.510.91.62.92.9-0.92.53.12.9-2.33.23.3-1.1
Pavlov. Cond. magazine entry latency6.28.014.3-2.6-2.9-3.2-0.1-2.3-3.4-3.32.8-3.8-3.60.6
Pavlov. Cond. change in total contacts7.78.212.1-1.9-2.9-3.41.4-3.1-3.2-2.92.9-3.2-3.52.2
Pavlov. Cond. index score7.08.914.9-2.0-3.4-3.40.8-2.9-3.6-3.42.7-3.8-3.91.1
Pavlov. Cond. latency score5.87.412.6-1.9-3.1-3.10.6-2.5-3.3-3.12.5-3.5-3.50.9
Pavlov. Cond. lever contacts7.58.814.2-2.1-3.2-3.40.9-2.9-3.5-3.42.8-3.7-3.81.3
Pavlov. Cond. magazine entry number6.88.513.42.03.13.4-0.92.93.53.3-2.83.63.7-1.5
Pavlov. Cond. intertrial magazine entries3.33.96.01.91.72.5-0.62.02.21.9-2.32.32.3-1.5
Pavlov. Cond. lever-magazine prob. diff.7.79.616.2-2.2-3.4-3.50.7-2.8-3.8-3.62.9-4.0-4.01.1
Pavlov. Cond. response bias8.410.216.0-2.2-3.4-3.71.2-3.3-3.8-3.53.1-3.8-4.01.8
Bone: apparent density0.20.41.7-1.20.6-0.2-1.30.5-0.0-0.40.5-0.20.1-0.4
Bone surface0.50.92.9-1.7-0.1-1.1-0.7-0.4-0.8-1.11.3-0.8-0.60.5
Bone volume0.50.93.7-1.90.4-0.8-1.30.2-0.4-1.11.2-0.7-0.30.1
Bone: connectivity density0.30.41.0-1.0-0.3-0.7-0.6-0.3-0.7-0.70.7-0.8-0.6-0.1
Bone: cortical apparent density0.40.51.31.20.40.70.80.20.90.5-0.60.90.70.5
Bone: cortical area1.01.56.6-2.60.7-0.9-1.90.4-0.4-1.11.6-1.0-0.30.2
Bone: cortical porosity0.80.91.5-1.2-0.7-0.8-0.9-0.4-1.2-1.20.5-1.1-0.9-0.8
Bone: cortical porosity0.70.71.4-0.7-1.0-0.7-0.6-0.5-1.2-1.00.1-1.0-0.9-1.0
Bone: cortical thickness0.61.03.0-1.51.60.2-1.71.20.90.30.70.40.90.1
Bone: cortical thickness1.92.25.20.02.31.4-1.11.72.01.5-0.51.82.00.0
Bone: cortical tissue density0.40.51.31.20.40.70.80.20.80.5-0.70.90.70.4
Bone: elastic displacement1.31.52.41.11.11.5-0.31.11.31.3-1.41.51.5-0.9
Bone: elastic work0.20.20.6-0.50.70.3-0.80.60.40.30.00.40.5-0.2
Bone: endosteal estimation1.43.15.8-2.3-1.0-2.0-0.7-1.0-1.8-2.42.1-2.2-1.90.6
Bone: endosteal perimeter1.42.94.8-1.9-1.0-2.00.2-1.3-1.6-2.22.2-1.9-1.81.5
Bone: final force1.62.710.7-3.30.7-1.3-2.40.6-0.6-1.42.2-1.6-0.70.1
Bone: final moment1.32.28.6-2.90.7-1.0-2.40.7-0.5-1.31.8-1.4-0.5-0.2
Bone: marrow area1.32.85.4-2.2-1.0-1.9-0.6-1.0-1.7-2.32.1-2.1-1.80.6
Bone: maximum diameter0.91.75.3-2.3-0.1-1.3-1.4-0.1-0.9-1.71.7-1.5-1.00.2
Bone: maximum force1.32.29.1-3.00.8-1.1-2.20.5-0.5-1.32.1-1.3-0.50.3
Bone: maximum moment1.01.77.1-2.70.8-0.9-2.20.6-0.4-1.11.7-1.1-0.4-0.1
Bone: minimum diameter1.32.45.9-2.4-0.6-1.8-0.9-0.8-1.4-2.12.0-1.8-1.40.7
Bone: periosteal estimation1.63.29.3-3.0-0.3-1.9-1.5-0.4-1.4-2.42.4-2.0-1.40.6
Bone: periosteal perimeter1.22.04.4-2.0-0.7-1.5-0.9-0.6-1.4-2.11.6-1.8-1.40.2
Bone: post-yield work1.31.73.6-1.7-0.6-0.9-1.90.1-1.3-1.70.7-1.7-1.1-1.5
Bone: stiffness1.01.56.3-2.51.2-0.8-1.70.70.1-0.71.9-0.8-0.10.7
Bone: tissue strength0.10.10.3-0.30.2-0.20.2-0.10.10.30.30.20.10.6
Bone: trabecular number0.20.31.0-0.90.80.0-1.00.60.30.20.40.10.3-0.2
Bone: trabecular spacing1.21.63.90.5-2.0-1.01.4-1.5-1.5-1.50.2-1.1-1.60.3
Bone: trabecular thickness2.73.39.7-0.92.21.5-3.12.51.50.4-0.80.91.8-2.2
Bone: trabecular tissue density0.20.20.60.10.70.5-0.20.70.80.2-0.10.40.60.1
Breakpoint value in progressive ratio session1.01.13.51.6-0.21.20.20.30.40.8-1.90.90.7-1.6
Distance traveled before self-admin0.70.71.7-0.41.30.7-0.10.81.11.00.01.11.10.3
Distance traveled after self-admin0.70.73.0-1.70.8-0.6-0.70.20.1-0.31.5-0.20.11.0
Delta time in closed arm before/after self-admin1.71.63.2-0.0-1.6-1.51.2-1.8-1.4-1.10.8-1.1-1.51.2
Delta time in open arm before/after self-admin0.90.83.8-1.11.00.3-2.01.40.5-0.30.4-0.30.3-0.8
Diff in mean of infusions in LGA sessions1.51.73.21.40.71.8-0.51.51.21.0-1.61.01.1-1.8
Extinction: sum of active levers before priming0.10.10.60.8-0.00.20.7-0.10.30.2-0.30.30.10.4
Active lever presses in extinction session 60.40.41.50.60.10.8-0.50.60.30.1-0.90.30.4-1.2
Delta distance traveled before/after self-admin1.21.22.0-1.4-0.7-1.4-0.6-0.8-1.3-1.31.2-1.3-1.10.3
Delta ambulatory time before/after self-admin0.70.71.6-1.3-0.3-1.1-0.7-0.5-0.9-0.91.1-1.0-0.80.4
Time in closed arm before self-admin0.40.51.4-0.80.90.4-1.21.10.50.10.10.10.5-0.7
Time in closed arm after self-admin1.31.32.31.20.81.4-0.20.91.11.3-1.51.31.3-1.1
Time in open arm before self-admin0.70.73.01.5-0.90.11.7-0.9-0.20.3-0.50.3-0.30.6
Time in open arm after self-admin0.80.92.7-1.2-0.0-1.0-0.3-0.2-0.4-1.11.6-1.0-0.81.2
Sum of active levers in priming session hrs 5-60.40.40.90.3-0.9-0.2-0.1-0.3-0.8-0.8-0.3-0.7-0.8-0.8
Time to tail flick, vehicle, before self-admin0.20.20.6-0.4-0.1-0.5-0.0-0.2-0.2-0.50.8-0.6-0.50.7
Time to tail flick, vehicle, after self-admin0.60.61.90.9-1.3-0.31.4-1.1-0.8-0.2-0.6-0.2-0.70.0
Time to tail flick, test, before self-admin0.40.42.1-0.3-0.1-0.60.6-0.5-0.1-0.10.9-0.3-0.41.5
Time to tail flick, test, after self-admin1.91.95.60.6-1.4-1.12.4-1.6-0.9-0.81.0-0.8-1.52.0
Delta time to tail flick, vehicle, before/after SA0.30.30.80.3-0.9-0.20.2-0.6-0.8-0.4-0.5-0.3-0.5-0.8
Delta time to tail flick, test, before/after SA0.50.50.80.1-0.9-0.60.8-0.7-0.8-0.80.4-0.7-0.90.3
Ambulatory time before self-admin1.41.52.9-0.01.71.2-0.21.21.61.6-0.41.61.70.1
Ambulatory time after self-admin0.80.83.5-1.91.0-0.6-0.70.20.3-0.01.50.00.31.1
Total heroin consumption0.40.52.60.7-0.70.50.0-0.0-0.30.1-1.30.1-0.0-1.6
Area under the delay curve0.50.61.70.50.70.60.10.20.81.3-0.61.11.00.1
Delay disc. indifference point, 0s delay0.50.52.2-0.81.0-0.30.00.10.50.21.00.30.41.5
Delay disc. indifference point, 16s delay3.33.37.22.70.61.91.00.51.52.6-2.42.31.8-0.8
Delay disc. indifference point, 2s delay1.21.35.1-2.30.6-1.1-1.50.2-0.4-0.91.8-0.9-0.40.7
Delay disc. indifference point, 24s delay1.61.53.92.00.00.91.7-0.30.81.6-1.61.60.90.3
Delay disc. indifference point, 4s delay1.51.53.00.21.71.1-0.61.11.61.7-0.41.61.70.1
Delay disc. indifference point, 8s delay0.30.30.9-0.20.70.10.2-0.00.51.00.10.80.70.6
Delay discount exponential model param0.40.41.5-0.5-0.5-0.5-0.2-0.1-0.6-1.20.5-1.0-0.8-0.1
Delay discount hyperbolic model param0.40.41.2-0.2-0.7-0.40.0-0.2-0.7-1.10.3-0.9-0.9-0.2
Fecal boli incidents, locomotor time 11.41.54.00.0-2.0-1.11.1-1.6-1.7-1.0-0.1-1.1-1.5-0.0
Change in fecal boli incidents, locomotor task3.53.35.4-0.02.11.9-2.32.21.81.1-1.21.72.3-2.0
Time >=10cm from walls, locomotor time 10.20.21.4-1.20.6-0.2-0.40.30.20.10.6-0.10.10.4
Bouts of movement, locomotor time 10.91.04.32.1-0.70.81.7-0.20.30.7-1.20.5-0.1-0.1
Total resting periods, locomotor time 11.01.14.52.1-1.00.61.9-0.60.10.7-1.20.5-0.10.0
Rest time, locomotor task time 10.70.73.10.6-0.3-0.41.8-1.2-0.10.7-0.10.70.21.4
Distance moved, locomotor task time 10.91.04.6-0.70.80.5-2.21.50.4-0.70.2-0.60.1-1.4
Vertical activity count, locomotor time 11.51.64.4-1.11.90.8-2.12.11.30.10.8-0.00.8-0.4
Time >=10cm from walls, locomotor time 20.80.84.2-2.10.5-0.9-0.9-0.1-0.3-0.61.3-0.5-0.20.7
Bouts of movement, locomotor time 23.84.17.4-0.8-2.5-2.21.1-2.1-2.5-2.31.4-2.5-2.70.7
Total resting periods, locomotor time 23.73.96.9-1.0-2.3-2.20.8-2.0-2.5-2.31.4-2.5-2.60.6
Rest time, locomotor task time 20.20.20.4-0.10.40.3-0.40.20.30.5-0.50.60.6-0.4
Distance moved, locomotor task time 20.30.41.5-0.50.8-0.20.00.30.5-0.31.1-0.10.11.2
Vertical activity count, locomotor time 21.11.33.9-0.22.00.9-0.71.51.70.80.40.91.20.6
Weight adjusted by age1.61.84.0-0.4-1.7-1.10.0-0.9-1.6-1.90.8-2.0-1.9-0.4
Seeking ratio, delayed vs. immediate footshock0.10.10.1-0.10.30.3-0.20.30.20.3-0.10.20.2-0.3
Locomotion in novel chamber0.50.62.5-0.6-0.20.1-1.40.8-0.3-0.6-0.1-0.9-0.4-1.6
Locomotion in novel chamber post-restriction1.01.23.51.10.41.4-0.91.50.90.3-1.50.40.7-1.9
Progressive ratio1.01.22.40.70.91.4-1.01.31.00.8-1.20.81.1-1.6
Food seeking constrained by brief footshock1.01.22.51.50.61.20.70.51.21.6-1.21.41.20.1
Seeking ratio, punishment vs. effort0.70.91.4-0.7-0.9-1.20.8-1.2-1.0-0.60.9-0.7-1.01.2
Run reversals in cocaine runway, females1.81.87.9-2.80.9-1.2-1.70.2-0.3-0.82.2-0.9-0.20.9
Run reversals in cocaine runway, males0.40.41.60.60.40.40.60.00.61.3-0.40.70.50.5
Latency to leave start box in cocaine runway1.11.32.60.60.71.3-0.91.10.81.1-1.61.01.2-1.6
Latency to leave start box in cocaine runway, F0.20.20.60.2-0.8-0.10.2-0.4-0.5-0.1-0.7-0.2-0.3-0.6
Latency to leave start box in cocaine runway, M3.43.24.70.91.92.1-1.32.01.92.0-1.81.92.2-1.6
Cd content in liver2.93.28.32.80.12.00.50.71.12.0-2.91.91.5-1.9
Co content in liver2.63.04.41.41.62.1-0.91.81.92.1-1.71.92.0-1.3
Cu content in liver1.01.22.50.01.21.2-1.51.61.10.9-0.70.61.0-1.3
Fe content in liver1.82.25.31.41.41.60.31.21.82.3-1.11.81.7-0.0
K content in liver0.10.10.40.0-0.3-0.0-0.20.2-0.2-0.60.1-0.5-0.4-0.4
Mg content in liver1.01.02.60.2-1.6-0.70.4-0.8-1.3-1.20.1-1.3-1.4-0.5
Mn content in liver0.60.71.1-0.8-0.7-1.00.4-0.9-0.9-0.71.1-1.0-1.00.9
Na content in liver4.64.99.5-3.0-1.1-2.6-0.1-1.4-2.0-2.63.1-2.7-2.31.8
Rb content in liver2.73.46.91.71.02.2-1.41.91.51.8-2.41.51.7-2.6
Se content in liver0.10.20.7-0.30.1-0.30.4-0.00.1-0.20.8-0.3-0.30.8
Sr content in liver0.40.40.8-0.9-0.3-0.6-0.4-0.2-0.5-0.80.7-0.8-0.60.2
Zn content in liver1.92.14.4-2.1-0.8-1.5-1.1-0.5-1.5-1.71.5-2.1-1.6-0.1