Hub : Genes

Fscn2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000036700	0.02	0.02	4.8e-03	0.01	0.01	0.01	0.01	2.1e-02	6.9e-03	3.7e-02	1.2e-02
2	Brain	mRNA stability	ENSRNOG00000036700	0.07	0.04	3.9e-05	0.03	0.04	0.04	0.04	4.8e-04	1.1e-04	1.4e-04	1.5e-04
3	PL	mRNA stability	ENSRNOG00000036700	0.05	0.03	6.9e-04	0.02	0.04	0.03	0.03	5.7e-03	6.2e-04	1.4e-03	2.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	0.2	0.6	1.4	0.5	0.1	-1.2
BMI without tail	1.5	3.1	7.7	1.2	-0.1	-2.8
Body weight	3.3	14.0	19.2	3.7	-3.0	-4.4
Epididymis fat weight	0.5	1.2	2.3	1.0	-0.5	-1.5
Glucose	0.6	0.9	2.3	-0.5	0.2	1.5
Heart weight	0.3	0.4	0.7	0.6	-0.3	-0.8
Left kidney weight	0.4	1.2	2.1	1.1	-1.4	-0.6
Right kidney weight	0.1	0.3	0.8	0.5	-0.9	-0.1
Tail length	3.6	10.9	16.6	3.1	-2.6	-4.1
Length with tail	3.6	13.1	13.2	3.6	-3.6	-3.6
Length without tail	1.0	2.1	4.3	1.4	-2.1	-0.3
Liver weight, left	0.1	0.2	0.5	0.5	-0.7	-0.1
Liver weight, right	3.0	5.0	5.6	2.2	-2.4	-2.1
Parametrial fat weight	1.6	3.2	4.0	1.8	-1.6	-2.0
Retroperitoneal fat weight	3.5	11.7	17.5	3.4	-2.5	-4.2
Intraocular pressure	0.1	0.2	0.5	0.3	-0.1	-0.7
Extensor digitorum longus weight	0.3	1.0	2.2	-0.9	1.5	0.1
Soleus weight	1.2	3.4	4.4	1.8	-1.7	-2.1
Tibialis anterior weight	0.0	0.1	0.1	-0.3	0.3	0.0
Tibia length	12.1	34.0	35.2	5.9	-5.7	-5.9
Number of licking bursts	0.0	0.0	0.1	0.1	-0.2	-0.3
Food consumed during 24 hour testing period	0.3	0.3	0.6	0.6	-0.3	-0.8
Times rat made contact with spout	2.4	2.8	3.1	1.8	-1.7	-1.5
Mean time between licks in bursts	1.6	2.2	2.7	-1.5	1.3	1.6
Mean num. licks in bursts	0.4	0.5	0.6	0.8	-0.6	-0.6
Std. dev. time between licks in bursts	0.5	0.6	1.3	-0.7	1.2	-0.2
Water consumed over 24 hours	0.3	0.3	0.6	0.6	-0.8	-0.2
Indifference point 0 sec	0.1	0.1	0.2	0.3	-0.0	-0.4
Indifference point AUC	0.0	0.0	0.1	-0.2	0.2	0.2
Indifference point function ln k	0.9	1.3	1.3	-1.1	1.1	1.1
Indifference point function log k	0.9	1.3	1.3	-1.1	1.1	1.1
Delay discounting total patch changes 0 sec	0.0	0.1	0.1	0.1	0.3	-0.3
Delay discounting total patch changes 12 sec	0.0	0.0	0.1	0.2	-0.2	-0.2
Delay discounting total patch changes 18 sec	0.7	0.9	1.6	-0.9	1.3	0.5
Delay discounting total patch changes 24 sec	0.3	0.4	0.8	0.6	-0.2	-0.9
Delay discounting total patch changes 6 sec	0.6	1.0	1.0	1.0	-1.0	-0.9
Delay discounting time to switch 0 sec	0.2	0.4	0.6	-0.6	0.4	0.8
Delay discounting water rate 0 sec	1.0	1.5	3.2	1.1	-0.5	-1.8
Delay discounting water rate 12 sec	0.3	0.4	0.9	-0.5	0.9	-0.1
Delay discounting water rate 18 sec	0.1	0.2	0.4	0.1	0.3	-0.6
Delay discounting water rate 24 sec	0.5	0.7	1.3	0.1	0.8	-1.2
Delay discounting water rate 6 sec	0.0	0.1	0.2	-0.2	0.4	-0.1
Locomotor activity	0.5	0.8	1.0	-0.8	0.8	1.0
Locomotor testing distance	0.9	1.6	1.8	-1.2	1.3	1.2
Locomotor testing rearing	0.6	0.9	1.4	-0.9	1.2	0.7
Light reinforcement 1	0.3	0.5	1.3	0.5	-0.0	-1.1
Light reinforcement 2	1.5	2.0	3.0	1.3	-1.1	-1.7
Reaction time number correct	2.2	3.2	5.8	-1.8	2.4	0.6
Reaction time mean minus median	0.2	0.2	0.5	0.4	-0.7	-0.0
Reaction time mean minus median AUC	0.2	0.3	0.5	0.5	-0.7	-0.2
Reaction time num false alarms	0.3	0.4	0.4	-0.6	0.6	0.6
Reaction time num false alarms AUC	0.7	1.0	1.1	-1.0	1.0	1.0
Reaction time trials correct on left	2.2	3.2	5.8	-1.8	2.4	0.6
Reaction time trials on left	2.3	3.2	6.0	-1.8	2.4	0.6
Reaction time mean	0.1	0.1	0.3	0.3	-0.1	-0.5
Reaction time mean AUC	0.0	0.1	0.1	0.1	0.2	-0.4
Median of all reaction times	0.1	0.1	0.2	0.1	0.2	-0.5
Reaction time omissions	0.0	0.0	0.1	0.1	0.2	-0.3
Reaction time false alarm rate	0.1	0.2	0.3	0.0	-0.3	0.6
Reaction time premature initiation rate	1.3	1.8	2.1	-1.3	1.2	1.4
Reaction time premature initiations	2.9	4.2	5.6	-2.1	2.4	1.6
Std. dev. reaction times	0.3	0.4	0.4	-0.6	0.6	0.7
Reaction time trials completed	2.3	3.2	6.0	-1.8	2.4	0.6
Reaction time trials AUC	2.1	3.1	5.7	-1.8	2.4	0.6
Social response proportion	0.8	0.8	0.9	-0.9	1.0	0.8
Social responses	0.1	0.2	0.2	-0.4	0.5	0.3
Social time	0.2	0.3	0.4	-0.5	0.6	0.4
Conditioned locomotion	2.1	2.5	4.4	1.4	-0.9	-2.1
Cocaine response after cond. corrected	0.0	0.0	0.0	-0.0	0.2	0.1
Cocaine response after cond. not corrected	0.3	0.3	0.5	-0.5	0.5	0.7
Cocaine response before conditioning	0.8	0.9	1.3	-1.0	0.7	1.1
Saline control response	2.7	3.7	4.7	1.9	-1.6	-2.2
Condit. Reinf. active minus inactive responses	0.5	0.7	0.9	0.8	-0.7	-0.9
Condit. Reinf. active-inactive response ratio	2.7	2.9	2.9	1.7	-1.7	-1.7
Condit. Reinf. active responses	0.0	0.0	0.1	-0.0	0.2	-0.3
Condit. Reinf. inactive responses	1.2	1.5	2.0	-1.2	1.4	1.0
Condit. Reinf. lever presses	0.2	0.3	0.6	-0.3	0.8	-0.2
Condit. Reinf. lever reinforcers received	0.1	0.2	0.5	-0.3	0.7	-0.2
Pavlov. Cond. lever latency	0.2	0.3	0.5	0.2	-0.7	0.5
Pavlov. Cond. magazine entry latency	3.8	4.4	5.6	-2.1	2.4	1.7
Pavlov. Cond. change in total contacts	1.2	1.7	3.1	-1.2	1.8	0.7
Pavlov. Cond. index score	1.2	1.6	3.0	-1.2	1.7	0.6
Pavlov. Cond. latency score	1.1	1.4	2.8	-1.1	1.7	0.5
Pavlov. Cond. lever contacts	0.2	0.3	0.4	-0.1	0.7	-0.7
Pavlov. Cond. magazine entry number	3.1	3.8	5.5	2.0	-2.3	-1.5
Pavlov. Cond. intertrial magazine entries	1.4	1.8	2.2	1.3	-1.2	-1.5
Pavlov. Cond. lever-magazine prob. diff.	1.5	1.9	3.5	-1.3	1.9	0.8
Pavlov. Cond. response bias	0.5	0.7	1.6	-0.8	1.3	0.1
Conditioned reinforcement - actives	0.0	0.0	0.0	-0.1	0.1	-0.1
Conditioned reinforcement - inactives	1.5	1.7	2.0	1.3	-1.1	-1.4
Conditioned locomotion	0.2	0.2	0.2	0.4	-0.5	-0.4
Intermittent access intake day 1-15 change	0.7	0.7	0.9	0.9	-0.7	-0.9
Intermittent access intake escalation	0.5	0.5	0.7	0.7	-0.5	-0.8
Intermittent access intake escalation 2	2.8	2.8	3.1	1.8	-1.6	-1.7
Intermitt. access day 1 inactive lever presses	1.3	1.4	1.8	1.2	-0.9	-1.3
Intermitt. access day 15 inactive lever presses	0.5	0.6	1.1	0.7	-0.4	-1.1
Intermitt. access escalation Index	0.2	0.2	0.5	0.3	-0.1	-0.7
Intermittent access day 1 total infusions	0.2	0.2	0.3	0.4	-0.4	-0.6
Intermittent access day 15 total infusions	0.4	0.5	0.8	0.7	-0.5	-0.9
Intermittent access terminal intake (last 3 days)	1.3	1.4	1.7	1.2	-1.0	-1.3
Intermittent access total infusions	0.4	0.4	0.6	0.6	-0.5	-0.8
Intermittent access day 1 locomotion	0.2	0.2	0.3	0.4	-0.3	-0.6
Intermittent access day 15 total locomotion	0.8	0.8	1.0	0.9	-1.0	-0.8
Intermittent access total locomotion	0.5	0.6	0.6	0.8	-0.7	-0.8
Intermittent access standard deviation	0.1	0.1	0.1	0.4	-0.4	0.1
Cocaine induced anxiety	6.1	7.1	8.0	2.8	-2.3	-2.8
Post-drug Anxiety	0.7	0.8	1.0	1.0	-0.7	-0.9
Baseline Anxiety	8.2	8.7	10.8	-3.0	2.5	3.3
Lifetime Intake	0.1	0.1	0.2	0.3	-0.4	-0.4
Incentive Sensitization - Responses	0.2	0.2	0.2	0.4	-0.5	-0.4
Incentive Sensitization - Breakpoint	0.2	0.2	0.3	0.4	-0.5	-0.4
Progressive ratio test 1 active lever presses	0.8	0.8	1.2	0.9	-0.7	-1.1
Progressive ratio test 1 breakpoint	1.1	1.1	1.6	1.0	-0.8	-1.3
Progressive ratio test 1 inactive lever presses	1.7	1.8	3.0	1.3	-0.8	-1.7
Progressive ratio test 2 active lever presses	0.5	0.5	0.6	0.7	-0.8	-0.7
Progressive ratio test 2 breakpoint	0.4	0.4	0.5	0.6	-0.6	-0.7
Progressive ratio test 2 inactive lever presses	0.6	0.7	0.7	0.8	-0.8	-0.8
Total sessions with >9 infusions	0.1	0.2	0.3	-0.4	0.1	0.6
Short access day 1 total inactive lever presses	0.1	0.1	0.1	-0.3	0.2	0.2
Short access day 10 total inactive lever presses	3.2	3.5	4.5	1.9	-1.6	-2.1
Short access day 1 total infusions	1.1	1.2	1.8	-1.1	0.8	1.3
Short access day 10 total infusions	0.7	0.8	0.8	0.9	-0.9	-0.9
Short access total infusions	0.0	0.0	0.0	0.0	-0.1	0.0
Short access day 1 locomotion	0.1	0.1	0.2	-0.0	-0.4	0.4
Short access day 10 total locomotion	0.2	0.2	0.5	0.5	-0.7	-0.0
Short access total locomotion	0.1	0.1	0.2	0.0	-0.5	0.4
Compulsive drug intake	0.2	0.1	0.4	0.3	0.1	-0.6
One hour access (0.3 mA shock)	0.8	0.9	1.5	0.9	-0.7	-1.2
One hour access (shock baseline)	0.1	0.2	0.2	0.3	-0.5	-0.4
Number of responses in last shaping day	1.0	1.0	1.2	1.0	-0.9	-1.1
Context. condit. distance diff. score	0.4	0.4	1.0	-0.6	1.0	-0.2
Locomotion velocity, session 1	0.8	0.8	1.9	-0.7	0.2	1.4
Locomotion distance, session 1	3.7	4.8	5.1	-2.3	2.1	2.2
Locomotion velocity, session 2	3.1	3.7	6.0	-1.9	1.2	2.4
Locomotion distance, session 2	1.0	1.4	1.6	-1.3	1.2	1.0
Locomotion velocity, session 3	0.8	1.0	1.7	-0.9	0.6	1.3
Locomotion distance, session 3	2.8	3.0	3.9	-1.7	1.5	2.0
Stereotopy head waving bouts, day 3	0.2	0.2	0.5	-0.3	0.0	0.7
Stereotopy head waving duration, day 3	0.1	0.2	0.3	-0.4	0.2	0.6
Locomotion velocity, session 7	0.8	0.9	0.9	-1.0	1.0	1.0
Locomotion distance, session 7	5.2	6.7	7.6	-2.7	2.8	2.3
Stereotopy head waving bouts, day 7	0.1	0.1	0.2	0.3	-0.1	-0.4
Stereotopy head waving duration, day 7	0.6	0.7	0.8	0.9	-0.9	-0.8
Locomotion velocity, session 8	1.5	1.8	2.2	-1.4	1.5	1.1
Locomotion distance, session 8	1.4	2.2	4.0	-1.5	2.0	0.5
Degree of sensitization distance	0.1	0.1	0.2	-0.0	0.3	-0.4
Degree of sensitization stereotypy	0.2	0.2	0.5	0.4	-0.1	-0.7
Condit. Reinf. active minus inactive responses	1.6	1.7	2.7	1.3	-0.9	-1.7
Condit. Reinf. active-inactive response ratio	0.6	0.7	1.2	0.8	-0.4	-1.1
Condit. Reinf. active responses	2.8	3.4	5.2	1.8	-1.4	-2.3
Condit. Reinf. inactive responses	0.7	0.8	1.2	0.8	-0.7	-1.1
Incentive salience index mean	1.3	1.5	2.3	1.2	-0.9	-1.5
Condit. Reinf. lever presses	0.0	0.0	0.1	-0.2	0.3	0.0
Time in familiar zone, hab. session 1	0.0	0.0	0.0	-0.0	0.1	0.1
Time in novel zone, hab. session 1	0.0	0.0	0.0	-0.1	0.1	-0.0
Total zone transitions, hab. session 1	0.8	1.1	1.5	-1.1	1.2	0.8
Total locomotion distance, hab. session 1	0.2	0.3	0.8	-0.4	0.9	-0.1
Locomotion velocity, hab. session 1	0.2	0.3	0.7	-0.3	0.8	-0.1
Time in familiar zone, hab. session 2	0.7	0.7	1.1	-0.8	1.0	0.6
Time in novel zone, hab. session 2	0.0	0.0	0.1	-0.1	-0.2	0.2
Total zone transitions, hab. session 2	1.6	2.0	2.9	-1.5	1.7	0.9
Total locomotion distance, hab. session 2	0.3	0.5	1.0	-0.6	1.0	-0.1
Locomotion velocity, hab. session 2	0.2	0.3	0.5	-0.3	0.7	-0.4
Novel to familiar place preference ratio	3.4	3.6	4.0	2.0	-1.7	-2.0
Novelty place preference	3.5	3.6	4.0	2.0	-1.7	-1.9
Time in novel zone, NPP test	2.6	2.7	3.0	1.7	-1.5	-1.7
Total zone transitions, NPP test	2.2	3.1	4.2	-1.9	2.0	1.3
Total locomotion distance, NPP test	1.1	1.5	2.8	-1.3	1.7	0.4
Locomotion velocity, NPP test	0.6	0.8	1.6	-0.9	1.3	0.1
Pavlov. Cond. lever latency	3.5	4.4	6.6	-2.1	2.6	1.5
Pavlov. Cond. magazine entry latency	4.1	5.3	5.8	2.4	-2.4	-2.1
Pavlov. Cond. change in total contacts	1.1	1.2	1.4	1.2	-1.2	-0.8
Pavlov. Cond. index score	5.3	6.8	7.5	2.7	-2.7	-2.4
Pavlov. Cond. latency score	5.1	6.5	7.9	2.6	-2.8	-2.2
Pavlov. Cond. lever contacts	2.1	2.5	3.4	1.6	-1.9	-1.2
Pavlov. Cond. magazine entry number	4.3	5.4	6.2	-2.5	2.5	2.0
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.3	-0.2	0.5	-0.2
Pavlov. Cond. lever-magazine prob. diff.	5.4	6.8	7.2	2.7	-2.7	-2.4
Pavlov. Cond. response bias	4.3	5.2	6.1	2.4	-2.5	-2.0
Bone: apparent density	0.0	0.1	0.2	0.2	0.0	-0.4
Bone surface	0.4	0.7	0.8	0.8	-0.9	-0.8
Bone volume	0.2	0.3	0.5	0.6	-0.5	-0.7
Bone: connectivity density	0.1	0.1	0.2	-0.5	0.4	0.3
Bone: cortical apparent density	2.1	2.7	3.6	-1.6	1.4	1.9
Bone: cortical area	7.2	10.9	12.6	3.4	-3.0	-3.6
Bone: cortical porosity	3.1	3.4	4.2	2.0	-2.0	-1.4
Bone: cortical porosity	2.9	3.1	3.7	1.9	-1.9	-1.5
Bone: cortical thickness	7.1	11.7	12.4	3.5	-3.3	-3.5
Bone: cortical thickness	2.0	2.3	2.8	1.6	-1.3	-1.7
Bone: cortical tissue density	2.4	3.1	4.1	-1.7	1.5	2.0
Bone: elastic displacement	1.9	2.2	2.4	1.5	-1.3	-1.5
Bone: elastic work	10.4	13.5	14.7	3.8	-3.5	-3.7
Bone: endosteal estimation	0.2	0.5	0.9	-0.7	0.9	0.2
Bone: endosteal perimeter	0.8	1.6	1.8	1.3	-1.2	-1.4
Bone: final force	5.5	8.9	11.5	3.0	-2.5	-3.4
Bone: final moment	6.6	10.8	13.7	3.3	-2.8	-3.7
Bone: marrow area	0.2	0.5	0.9	-0.7	0.9	0.2
Bone: maximum diameter	2.0	3.6	3.8	1.9	-1.8	-2.0
Bone: maximum force	5.1	8.8	11.6	3.0	-2.5	-3.4
Bone: maximum moment	6.1	10.6	13.7	3.3	-2.7	-3.7
Bone: minimum diameter	3.8	6.9	8.4	2.7	-2.3	-2.9
Bone: periosteal estimation	1.7	3.4	4.8	1.8	-1.4	-2.2
Bone: periosteal perimeter	5.4	8.9	9.4	3.1	-3.0	-2.8
Bone: post-yield work	0.2	0.3	0.4	-0.6	0.7	0.3
Bone: stiffness	0.5	0.8	1.2	0.9	-0.7	-1.1
Bone: tissue strength	0.6	0.6	1.1	0.7	-0.4	-1.1
Bone: trabecular number	0.0	0.0	0.0	0.0	-0.1	-0.0
Bone: trabecular spacing	0.9	1.1	2.4	-1.0	1.6	0.1
Bone: trabecular thickness	1.7	2.0	2.7	1.5	-1.6	-1.0
Bone: trabecular tissue density	0.7	1.0	1.3	-1.0	0.8	1.2
Breakpoint value in progressive ratio session	0.5	0.6	0.7	0.9	-0.5	-0.9
Distance traveled before self-admin	1.8	1.9	2.3	1.5	-1.1	-1.5
Distance traveled after self-admin	0.1	0.2	0.3	0.1	0.3	-0.6
Delta time in closed arm before/after self-admin	0.1	0.1	0.3	0.1	-0.5	0.2
Delta time in open arm before/after self-admin	0.3	0.3	0.7	-0.4	0.8	-0.0
Diff in mean of infusions in LGA sessions	0.1	0.1	0.1	-0.2	0.2	0.3
Extinction: sum of active levers before priming	0.8	0.8	1.1	-0.8	0.8	1.0
Active lever presses in extinction session 6	0.0	0.0	0.0	0.2	0.1	0.0
Delta distance traveled before/after self-admin	1.3	1.4	1.9	-1.3	1.4	0.9
Delta ambulatory time before/after self-admin	2.3	2.5	2.7	-1.7	1.6	1.5
Time in closed arm before self-admin	0.0	0.0	0.0	0.0	-0.1	0.2
Time in closed arm after self-admin	0.3	0.3	0.6	0.2	-0.8	0.5
Time in open arm before self-admin	0.1	0.1	0.1	-0.1	-0.3	0.3
Time in open arm after self-admin	0.4	0.4	0.6	-0.6	0.8	0.4
Sum of active levers in priming session hrs 5-6	0.4	0.4	0.8	0.6	0.0	-0.9
Time to tail flick, vehicle, before self-admin	0.0	0.0	0.0	0.1	-0.1	-0.2
Time to tail flick, vehicle, after self-admin	1.6	1.7	2.7	-1.3	0.8	1.7
Time to tail flick, test, before self-admin	0.2	0.2	0.3	0.4	-0.6	-0.2
Time to tail flick, test, after self-admin	0.1	0.1	0.2	-0.2	-0.0	0.4
Delta time to tail flick, vehicle, before/after SA	0.6	0.5	0.6	-0.8	0.7	0.7
Delta time to tail flick, test, before/after SA	0.2	0.2	0.3	-0.3	0.3	0.6
Ambulatory time before self-admin	2.9	3.1	3.9	1.8	-1.4	-2.0
Ambulatory time after self-admin	0.1	0.1	0.3	0.2	0.1	-0.5
Total heroin consumption	0.2	0.3	0.4	0.7	-0.4	-0.5
Area under the delay curve	1.8	1.9	2.3	-1.4	1.2	1.5
Delay disc. indifference point, 0s delay	0.0	0.0	0.0	-0.1	0.1	0.1
Delay disc. indifference point, 16s delay	3.8	3.9	4.5	-2.0	2.1	1.7
Delay disc. indifference point, 2s delay	0.2	0.2	0.3	-0.4	0.3	0.6
Delay disc. indifference point, 24s delay	3.4	3.3	5.0	-1.7	1.4	2.2
Delay disc. indifference point, 4s delay	0.3	0.3	0.5	-0.5	0.3	0.7
Delay disc. indifference point, 8s delay	0.4	0.4	0.8	-0.6	0.4	0.9
Delay discount exponential model param	2.1	2.3	3.0	1.5	-1.3	-1.7
Delay discount hyperbolic model param	2.0	2.2	2.9	1.4	-1.2	-1.7
Fecal boli incidents, locomotor time 1	0.7	0.7	0.8	-0.9	0.7	0.9
Change in fecal boli incidents, locomotor task	0.5	0.5	1.2	-0.5	0.2	1.1
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.0	-0.2	0.2	-0.2
Bouts of movement, locomotor time 1	1.5	1.7	2.2	-1.3	1.1	1.5
Total resting periods, locomotor time 1	1.4	1.5	2.4	-1.2	0.9	1.5
Rest time, locomotor task time 1	0.0	0.1	0.1	0.1	-0.3	0.2
Distance moved, locomotor task time 1	0.2	0.2	0.5	0.4	-0.2	-0.7
Vertical activity count, locomotor time 1	0.3	0.3	0.7	0.3	-0.0	-0.8
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.3	0.2	-0.6	0.0
Bouts of movement, locomotor time 2	1.6	1.7	2.0	-1.4	1.2	1.4
Total resting periods, locomotor time 2	1.3	1.4	1.6	-1.2	1.1	1.2
Rest time, locomotor task time 2	0.0	0.0	0.1	-0.1	-0.2	0.2
Distance moved, locomotor task time 2	0.0	0.0	0.0	0.1	-0.1	-0.1
Vertical activity count, locomotor time 2	0.1	0.1	0.2	-0.3	0.4	-0.0
Weight adjusted by age	2.8	3.1	4.3	1.8	-1.3	-2.1
Seeking ratio, delayed vs. immediate footshock	1.3	1.5	1.9	1.2	-1.1	-1.4
Locomotion in novel chamber	0.4	0.5	0.7	-0.7	0.9	0.6
Locomotion in novel chamber post-restriction	2.1	2.5	2.8	1.5	-1.5	-1.7
Progressive ratio	0.4	0.4	0.6	-0.6	0.6	0.7
Food seeking constrained by brief footshock	0.0	0.0	0.1	-0.0	0.0	0.2
Seeking ratio, punishment vs. effort	0.1	0.1	0.2	0.2	-0.1	-0.4
Run reversals in cocaine runway, females	2.1	2.1	2.9	-1.5	1.7	1.1
Run reversals in cocaine runway, males	2.7	2.6	3.0	1.7	-1.7	-1.4
Latency to leave start box in cocaine runway	0.4	0.5	0.5	-0.7	0.6	0.7
Latency to leave start box in cocaine runway, F	0.7	0.8	1.0	-1.0	0.9	0.8
Latency to leave start box in cocaine runway, M	0.1	0.1	0.1	0.3	-0.4	-0.2
Cd content in liver	2.8	3.0	3.3	-1.7	1.8	1.6
Co content in liver	0.2	0.2	0.4	-0.4	0.6	0.3
Cu content in liver	1.3	1.5	2.0	1.3	-1.4	-0.9
Fe content in liver	1.1	1.3	1.4	-1.1	1.1	1.2
K content in liver	1.2	1.2	1.9	1.0	-0.9	-1.4
Mg content in liver	0.1	0.2	0.3	-0.5	0.5	0.0
Mn content in liver	0.5	0.6	0.8	0.7	-0.9	-0.6
Na content in liver	0.1	0.1	0.2	0.3	-0.4	-0.2
Rb content in liver	0.2	0.2	0.6	0.3	0.0	-0.7
Se content in liver	0.1	0.2	0.3	0.4	-0.2	-0.6
Sr content in liver	0.4	0.4	0.7	0.6	-0.8	-0.1
Zn content in liver	0.3	0.3	0.8	0.4	-0.9	-0.0