Hub : Genes

Nploc4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000036698 0.05 0.03 9.9e-05 0.04 0.03 0.04 0.03 7.0e-05 1.1e-04 5.9e-05 1.7e-04
2 BLA gene expression ENSRNOG00000036698 0.51 0.15 0.0e+00 0.4 0.48 0.47 0.48 1.2e-22 1.5e-28 1.6e-27 1.7e-28
3 BLA mRNA stability ENSRNOG00000036698 0.09 0.06 8.9e-05 0.07 0.07 0.08 0.06 2.1e-04 8.4e-05 4.5e-05 2.4e-04
4 Brain gene expression ENSRNOG00000036698 0.81 0 0.0e+00 0.59 0.62 0.62 0.62 6.2e-68 1.6e-73 5.2e-74 4.8e-73
5 Brain mRNA stability ENSRNOG00000036698 0.41 0.24 0.0e+00 0.2 0.26 0.27 0.27 6.3e-18 6.1e-24 1.2e-24 5.8e-25
6 IL gene expression ENSRNOG00000036698 0.27 0.15 2.8e-04 0.03 0.09 0.07 0 6.5e-02 4.4e-03 9.9e-03 3.2e-01
7 LHb gene expression ENSRNOG00000036698 0.47 0.18 1.3e-07 0.12 0.08 0.16 0.03 1.1e-03 5.2e-03 1.5e-04 7.9e-02
8 Liver gene expression ENSRNOG00000036698 0.06 0.06 1.2e-04 0.04 0.03 0.04 0.03 2.1e-05 1.1e-04 4.6e-05 1.3e-04
9 NAcc gene expression ENSRNOG00000036698 0.11 0.06 1.7e-06 0.06 0.06 0.04 0.06 2.3e-05 1.4e-05 2.7e-04 5.1e-05
10 NAcc intron excision ratio chr10:105689731:105692037 0.03 0.02 8.0e-03 0.03 0.02 0.02 0.03 1.9e-03 8.8e-03 1.0e-02 4.7e-03
11 NAcc mRNA stability ENSRNOG00000036698 0.05 0.03 1.5e-03 0.03 0.02 0.03 0.03 2.3e-03 6.9e-03 3.9e-03 3.3e-03
12 OFC gene expression ENSRNOG00000036698 0.45 0.16 5.8e-08 0.19 0.18 0.17 0.19 3.0e-05 4.2e-05 7.9e-05 2.8e-05
13 OFC mRNA stability ENSRNOG00000036698 0.23 0.13 1.2e-03 0.08 0.08 0.04 0.04 6.4e-03 5.9e-03 3.8e-02 3.7e-02
14 PL gene expression ENSRNOG00000036698 0.43 0.15 0.0e+00 0.35 0.44 0.44 0.45 2.8e-27 1.0e-36 7.0e-37 4.6e-37
15 PL mRNA stability ENSRNOG00000036698 0.23 0.11 3.1e-12 0.16 0.17 0.16 0.17 2.5e-12 9.7e-13 1.7e-12 4.6e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail1.13.46.01.32.02.51.71.71.92.0-1.51.91.41.62.21.82.01.9
BMI without tail9.118.927.71.94.75.34.04.24.74.9-3.64.64.34.04.94.14.64.4
Body weight3.414.222.9-1.63.93.34.84.34.34.1-4.83.64.12.73.31.74.43.9
Epididymis fat weight1.63.64.80.32.12.02.02.02.12.0-1.92.01.51.72.01.62.22.2
Glucose6.710.215.3-0.4-3.6-3.0-3.0-3.6-3.2-3.32.6-3.8-2.5-3.9-3.3-3.0-3.3-3.9
Heart weight0.30.40.8-0.20.70.90.60.70.80.7-0.70.50.80.50.70.40.80.6
Left kidney weight0.20.64.4-2.1-0.4-0.90.3-0.2-0.2-0.4-0.4-0.5-0.1-0.7-0.8-1.2-0.1-0.2
Right kidney weight0.10.32.5-1.6-0.3-0.80.2-0.2-0.3-0.40.0-0.2-0.3-0.1-0.7-0.8-0.1-0.0
Tail length5.918.023.9-1.44.53.84.94.84.84.7-4.74.44.93.73.82.54.64.4
Length with tail1.65.913.0-3.22.21.03.52.92.72.3-3.61.92.91.21.1-0.22.72.2
Length without tail2.04.49.4-3.0-2.1-3.0-0.6-1.4-1.7-2.10.4-2.2-1.4-2.3-2.7-3.1-1.5-1.8
Liver weight, left0.71.11.9-1.0-1.1-1.1-0.6-1.0-0.9-1.00.4-1.3-0.6-1.3-1.2-1.4-0.9-1.1
Liver weight, right1.32.25.7-2.41.20.32.31.71.51.3-2.21.11.60.90.5-0.31.61.4
Parametrial fat weight1.22.44.4-1.01.51.22.11.81.81.7-2.11.41.81.11.20.41.81.6
Retroperitoneal fat weight4.113.620.7-0.83.93.74.54.24.34.0-4.53.53.72.73.42.04.43.7
Intraocular pressure0.81.11.90.51.11.10.81.01.21.2-1.01.11.40.81.10.91.01.1
Extensor digitorum longus weight0.73.06.02.21.82.10.91.41.41.7-0.61.90.62.12.32.51.41.7
Soleus weight1.23.55.7-1.21.91.52.42.22.11.9-2.31.92.11.61.40.72.12.0
Tibialis anterior weight0.20.51.30.40.80.70.60.70.60.7-0.31.00.41.10.80.90.60.9
Tibia length4.111.627.5-4.32.71.94.93.63.93.1-5.22.15.10.81.2-1.03.92.6
Number of licking bursts0.40.40.9-0.20.70.50.80.70.60.5-0.50.80.40.90.50.50.70.9
Food consumed during 24 hour testing period0.40.50.80.30.80.10.80.80.80.9-0.90.70.80.50.80.50.90.7
Times rat made contact with spout0.40.51.4-1.2-0.1-0.60.80.10.40.1-0.9-0.40.9-0.9-0.5-1.10.4-0.3
Mean time between licks in bursts0.91.32.50.5-1.1-1.0-1.6-1.1-1.3-1.21.6-0.9-1.6-0.5-0.8-0.2-1.4-1.0
Mean num. licks in bursts0.20.31.2-0.2-0.4-0.6-0.2-0.4-0.1-0.2-0.2-0.70.3-1.1-0.4-0.8-0.2-0.7
Std. dev. time between licks in bursts3.64.37.51.52.32.01.22.11.82.1-1.12.51.12.72.52.71.82.4
Water consumed over 24 hours0.60.71.6-0.9-0.9-1.1-0.2-0.7-0.7-0.80.3-1.0-0.3-1.1-1.1-1.2-0.6-0.9
Indifference point 0 sec0.10.10.20.40.30.50.30.30.40.4-0.30.20.20.20.50.30.40.2
Indifference point AUC0.00.00.10.30.10.0-0.1-0.00.10.10.10.10.20.10.10.20.0-0.0
Indifference point function ln k0.40.51.21.1-0.6-0.3-1.0-0.8-0.8-0.71.0-0.6-1.1-0.2-0.30.1-0.8-0.6
Indifference point function log k0.40.51.21.1-0.6-0.3-1.0-0.8-0.8-0.71.0-0.6-1.1-0.2-0.30.1-0.8-0.6
Delay discounting total patch changes 0 sec0.20.30.70.80.50.70.30.30.50.6-0.40.30.20.40.70.60.50.3
Delay discounting total patch changes 12 sec0.00.00.2-0.0-0.2-0.1-0.1-0.3-0.0-0.10.1-0.30.2-0.5-0.2-0.3-0.1-0.3
Delay discounting total patch changes 18 sec0.40.53.11.80.50.8-0.40.40.30.50.00.5-0.10.80.91.20.20.4
Delay discounting total patch changes 24 sec0.70.91.30.31.01.00.91.11.11.1-1.10.80.70.81.10.81.00.9
Delay discounting total patch changes 6 sec0.10.20.8-0.90.2-0.00.60.30.50.4-0.60.10.6-0.20.0-0.40.40.1
Delay discounting time to switch 0 sec0.40.71.0-0.1-0.9-0.8-0.9-0.8-0.9-0.90.8-0.8-0.9-0.8-0.7-0.6-1.0-0.8
Delay discounting water rate 0 sec2.94.76.10.72.42.32.22.22.42.5-2.22.12.12.02.31.82.42.2
Delay discounting water rate 12 sec1.21.73.11.81.41.60.81.01.21.3-0.71.40.81.51.61.71.11.2
Delay discounting water rate 18 sec1.92.53.50.91.81.71.41.61.61.7-1.31.81.11.91.81.71.61.8
Delay discounting water rate 24 sec5.17.010.32.32.93.12.12.52.72.9-2.12.72.02.73.23.02.72.6
Delay discounting water rate 6 sec0.50.71.31.00.90.80.60.80.80.9-0.51.00.51.11.01.00.90.9
Locomotor activity0.50.81.30.5-0.9-0.7-1.1-0.9-1.0-0.91.0-0.9-1.1-0.8-0.6-0.3-1.0-0.8
Locomotor testing distance0.30.51.70.9-0.4-0.4-1.1-0.5-0.8-0.60.7-0.4-1.3-0.3-0.00.4-0.8-0.3
Locomotor testing rearing0.10.21.71.30.10.1-0.40.1-0.2-0.00.20.1-0.60.20.30.7-0.10.1
Light reinforcement 12.34.26.70.52.32.32.02.22.12.0-1.82.31.32.12.22.02.32.6
Light reinforcement 22.83.65.9-0.62.11.82.32.22.01.9-2.12.01.51.81.71.22.22.4
Reaction time number correct4.36.213.63.02.62.90.92.31.82.2-0.82.80.83.43.13.71.82.7
Reaction time mean minus median0.50.71.4-1.0-0.9-1.0-0.4-0.6-0.7-0.80.3-0.9-0.7-1.0-1.0-1.2-0.6-0.8
Reaction time mean minus median AUC0.20.21.4-1.2-0.2-0.70.20.2-0.2-0.3-0.2-0.2-0.2-0.1-0.5-0.6-0.10.1
Reaction time num false alarms0.20.30.80.4-0.5-0.1-0.9-0.7-0.5-0.40.6-0.5-0.6-0.4-0.1-0.0-0.6-0.6
Reaction time num false alarms AUC0.40.51.40.5-0.7-0.4-1.2-0.8-0.8-0.60.8-0.6-1.0-0.3-0.20.0-0.9-0.8
Reaction time trials correct on left4.36.213.63.02.62.90.92.31.82.2-0.82.80.83.43.13.71.82.7
Reaction time trials on left4.56.414.03.12.62.91.02.31.92.2-0.92.90.83.43.13.71.82.8
Reaction time mean0.40.50.80.40.80.80.70.90.70.7-0.80.70.40.70.80.60.90.8
Reaction time mean AUC0.70.91.30.71.01.00.81.10.90.9-0.81.00.41.01.11.01.01.1
Median of all reaction times0.70.91.30.81.01.10.81.10.91.0-0.81.00.61.01.11.01.01.0
Reaction time omissions0.40.61.30.20.80.60.61.10.70.8-0.90.80.20.91.00.80.60.8
Reaction time false alarm rate2.02.84.0-1.0-1.8-1.7-1.5-1.9-1.6-1.61.2-1.9-1.2-2.0-1.7-1.8-1.7-2.0
Reaction time premature initiation rate1.21.63.20.9-1.2-0.9-1.8-1.6-1.3-1.21.4-1.2-1.3-1.3-0.8-0.4-1.4-1.3
Reaction time premature initiations0.60.96.12.50.30.7-1.0-0.2-0.20.10.80.5-0.70.60.91.6-0.30.3
Std. dev. reaction times0.10.20.70.5-0.4-0.3-0.6-0.3-0.5-0.40.5-0.3-0.8-0.2-0.20.0-0.5-0.3
Reaction time trials completed4.56.414.03.12.62.91.02.31.92.2-0.92.90.83.43.13.71.82.8
Reaction time trials AUC4.66.514.03.02.63.01.02.41.92.3-0.92.90.83.53.23.71.92.8
Social response proportion0.10.10.90.9-0.1-0.1-0.5-0.2-0.3-0.10.5-0.0-0.50.20.10.5-0.4-0.1
Social responses0.10.10.30.40.20.10.00.2-0.00.00.10.2-0.50.40.20.40.00.3
Social time0.10.10.80.90.20.3-0.0-0.0-0.00.00.30.2-0.20.30.10.50.00.2
Conditioned locomotion5.46.47.90.22.72.52.82.82.82.7-2.72.72.62.32.41.82.82.7
Cocaine response after cond. corrected0.30.30.80.4-0.6-0.3-0.6-0.6-0.4-0.40.3-0.7-0.2-0.9-0.3-0.4-0.5-0.8
Cocaine response after cond. not corrected0.70.81.30.3-1.0-0.7-1.1-1.0-0.9-0.90.9-1.0-0.7-1.0-0.8-0.6-1.0-1.1
Cocaine response before conditioning0.30.40.90.2-0.5-0.7-0.7-0.5-0.8-0.70.9-0.3-0.90.1-0.5-0.0-0.7-0.3
Saline control response2.43.25.2-1.01.81.52.32.02.11.9-2.21.72.31.31.40.72.01.8
Condit. Reinf. active minus inactive responses0.81.02.1-0.41.10.71.31.11.11.1-1.11.01.40.80.80.51.11.1
Condit. Reinf. active-inactive response ratio1.21.23.1-1.30.90.51.71.11.21.0-1.50.81.80.40.4-0.21.20.9
Condit. Reinf. active responses0.50.60.90.70.90.80.60.70.80.9-0.60.91.00.70.90.90.80.8
Condit. Reinf. inactive responses0.30.32.31.5-0.10.3-0.8-0.4-0.3-0.10.7-0.0-0.50.00.40.8-0.3-0.2
Condit. Reinf. lever presses0.91.22.51.61.11.30.60.91.01.2-0.71.10.80.91.51.41.01.0
Condit. Reinf. lever reinforcers received0.81.11.91.31.11.20.60.81.01.2-0.71.10.90.91.41.30.90.9
Pavlov. Cond. lever latency1.92.64.1-1.5-1.7-1.9-1.1-1.6-1.5-1.71.2-1.7-1.0-1.5-2.0-2.0-1.5-1.6
Pavlov. Cond. magazine entry latency0.80.96.42.5-0.10.4-1.2-0.4-0.6-0.21.20.1-1.20.40.61.3-0.5-0.2
Pavlov. Cond. change in total contacts0.71.05.42.30.71.2-0.30.40.40.70.10.7-0.20.81.41.70.40.6
Pavlov. Cond. index score0.81.05.52.30.81.2-0.20.50.50.8-0.00.7-0.10.81.41.70.50.6
Pavlov. Cond. latency score0.91.25.12.30.91.3-0.00.70.60.9-0.10.9-0.01.01.51.80.60.7
Pavlov. Cond. lever contacts2.43.45.11.52.02.11.31.91.82.0-1.42.01.31.92.32.21.81.9
Pavlov. Cond. magazine entry number0.81.07.4-2.7-0.2-0.71.00.10.3-0.1-0.8-0.31.0-0.6-0.9-1.60.2-0.1
Pavlov. Cond. intertrial magazine entries1.41.83.1-0.81.41.01.71.51.61.5-1.61.31.81.11.00.51.51.4
Pavlov. Cond. lever-magazine prob. diff.0.81.06.12.50.71.1-0.40.40.30.60.10.6-0.30.71.41.70.30.5
Pavlov. Cond. response bias1.21.64.02.01.31.50.41.11.01.2-0.51.30.51.31.71.91.01.1
Conditioned reinforcement - actives0.40.40.7-0.10.80.80.80.70.50.4-0.50.80.10.70.50.70.60.7
Conditioned reinforcement - inactives1.01.12.7-0.81.00.61.41.41.21.2-1.60.71.30.50.80.21.00.8
Conditioned locomotion0.30.30.8-0.90.60.10.80.70.40.5-0.80.50.10.40.30.20.60.7
Intermittent access intake day 1-15 change0.40.30.9-0.10.50.60.70.70.70.7-0.80.40.90.20.5-0.00.70.4
Intermittent access intake escalation0.50.50.8-0.00.70.80.80.80.80.8-0.90.60.90.40.60.20.80.7
Intermittent access intake escalation 20.60.62.0-0.90.50.51.20.80.90.8-1.40.21.0-0.10.5-0.50.90.5
Intermitt. access day 1 inactive lever presses0.50.61.4-0.50.70.21.00.81.01.0-1.20.41.00.20.70.10.80.4
Intermitt. access day 15 inactive lever presses1.82.03.40.21.61.11.61.81.51.5-1.81.41.21.51.41.11.41.5
Intermitt. access escalation Index2.11.93.1-0.21.61.11.31.71.41.4-1.41.61.11.71.41.31.31.6
Intermittent access day 1 total infusions0.30.41.0-0.20.61.00.70.50.70.6-0.50.70.90.30.50.30.70.5
Intermittent access day 15 total infusions0.80.91.5-0.21.01.21.11.11.11.0-1.11.01.20.70.90.61.00.9
Intermittent access terminal intake (last 3 days)1.11.22.1-0.71.11.31.41.21.21.1-1.41.01.30.60.80.31.20.9
Intermittent access total infusions0.70.71.3-0.30.91.21.10.91.00.9-0.90.91.10.60.70.50.90.8
Intermittent access day 1 locomotion0.70.70.9-0.30.90.60.90.90.91.0-0.90.90.80.70.80.60.90.8
Intermittent access day 15 total locomotion0.30.30.9-0.90.40.20.80.40.50.4-0.70.30.8-0.10.1-0.30.60.3
Intermittent access total locomotion0.50.51.1-0.60.70.41.00.90.80.8-1.00.70.80.40.50.20.80.7
Intermittent access standard deviation1.21.33.1-0.3-1.2-1.0-0.8-1.2-1.0-1.10.7-1.5-0.9-1.8-1.1-1.3-0.9-1.2
Cocaine induced anxiety1.21.44.6-1.40.80.71.81.41.41.2-2.10.21.5-0.10.7-0.61.40.6
Post-drug Anxiety0.10.10.40.1-0.1-0.20.30.10.20.1-0.5-0.50.4-0.7-0.1-0.50.2-0.3
Baseline Anxiety3.94.28.41.5-1.9-1.8-2.6-2.4-2.5-2.22.9-1.4-2.5-1.1-1.6-0.3-2.4-1.8
Lifetime Intake0.20.20.5-0.30.50.70.70.60.50.4-0.50.50.60.30.30.20.50.4
Incentive Sensitization - Responses0.10.10.6-0.40.2-0.00.40.20.30.3-0.30.20.8-0.00.0-0.10.20.2
Incentive Sensitization - Breakpoint0.10.10.4-0.50.1-0.10.30.10.20.1-0.20.10.6-0.2-0.1-0.20.10.1
Progressive ratio test 1 active lever presses1.31.32.0-0.31.21.11.41.31.31.2-1.31.21.20.91.00.71.31.2
Progressive ratio test 1 breakpoint1.61.62.4-0.31.31.21.61.41.51.4-1.41.31.41.01.20.71.51.3
Progressive ratio test 1 inactive lever presses3.13.44.4-0.22.01.92.12.12.12.0-2.11.81.81.71.81.32.01.8
Progressive ratio test 2 active lever presses0.30.30.8-0.60.50.30.90.50.60.5-0.70.50.90.00.2-0.00.60.5
Progressive ratio test 2 breakpoint0.50.61.1-0.40.80.61.10.70.80.7-0.80.81.10.30.50.30.80.8
Progressive ratio test 2 inactive lever presses0.20.30.7-0.70.40.60.80.60.60.5-0.90.30.8-0.00.2-0.10.50.4
Total sessions with >9 infusions0.10.10.2-0.2-0.3-0.4-0.1-0.2-0.4-0.40.3-0.1-0.40.1-0.4-0.2-0.4-0.3
Short access day 1 total inactive lever presses0.30.30.7-0.40.70.40.40.70.40.5-0.50.90.30.70.60.70.40.7
Short access day 10 total inactive lever presses2.02.25.2-0.81.51.12.11.51.81.6-1.91.22.30.81.10.31.71.3
Short access day 1 total infusions1.21.32.50.2-1.2-0.9-1.2-1.1-1.4-1.31.2-1.0-1.6-0.7-1.1-0.6-1.4-1.2
Short access day 10 total infusions0.30.30.8-0.60.50.50.90.60.70.6-0.70.40.90.20.3-0.10.70.4
Short access total infusions0.00.00.1-0.1-0.10.30.10.1-0.0-0.10.00.00.00.0-0.1-0.1-0.0-0.2
Short access day 1 locomotion0.90.91.3-1.0-1.0-1.1-0.5-0.8-1.0-1.10.8-0.9-0.9-0.9-1.1-1.1-1.0-1.0
Short access day 10 total locomotion0.70.81.5-1.0-0.9-1.2-0.4-0.8-0.8-0.80.4-1.0-0.6-1.2-1.0-1.2-0.8-1.0
Short access total locomotion1.11.11.6-1.1-1.1-1.3-0.6-1.1-1.0-1.00.8-1.0-0.7-1.2-1.2-1.2-1.0-1.2
Compulsive drug intake0.70.71.20.60.90.50.60.90.91.0-0.90.80.60.81.10.91.00.8
One hour access (0.3 mA shock)1.61.82.70.21.51.31.61.41.51.5-1.41.41.60.91.20.91.61.3
One hour access (shock baseline)0.40.41.0-0.60.70.71.00.70.60.6-0.50.80.70.50.30.30.60.8
Number of responses in last shaping day1.21.32.7-1.21.20.41.31.61.11.1-1.61.10.81.20.90.51.01.1
Context. condit. distance diff. score2.83.45.51.62.02.11.21.81.71.9-1.02.11.02.32.32.31.72.0
Locomotion velocity, session 14.54.85.9-0.7-2.4-2.3-2.2-2.4-2.3-2.42.0-2.4-1.8-2.3-2.3-2.0-2.4-2.4
Locomotion distance, session 11.01.33.41.5-0.8-0.5-1.7-1.1-1.3-0.91.8-0.5-1.70.0-0.30.6-1.3-0.7
Locomotion velocity, session 24.55.37.40.1-2.4-2.4-2.6-2.5-2.7-2.62.7-2.2-2.5-1.7-2.3-1.4-2.7-2.3
Locomotion distance, session 20.20.21.21.10.20.2-0.5-0.1-0.20.10.60.4-0.40.70.40.9-0.20.2
Locomotion velocity, session 32.32.73.4-0.2-1.8-1.5-1.8-1.8-1.8-1.81.7-1.8-1.9-1.6-1.6-1.2-1.8-1.8
Locomotion distance, session 32.52.84.60.9-1.7-1.3-2.1-1.9-1.9-1.82.1-1.6-2.1-1.2-1.2-0.6-1.9-1.7
Stereotopy head waving bouts, day 31.01.21.6-0.4-1.2-1.2-0.9-1.2-1.2-1.21.0-1.2-1.0-1.1-1.3-1.1-1.1-1.2
Stereotopy head waving duration, day 30.40.50.6-0.1-0.8-0.7-0.6-0.7-0.8-0.80.7-0.7-0.7-0.6-0.8-0.6-0.7-0.7
Locomotion velocity, session 70.40.41.10.8-0.5-0.3-0.9-0.7-0.7-0.60.9-0.5-1.1-0.3-0.20.1-0.6-0.5
Locomotion distance, session 71.11.36.72.6-0.40.1-1.6-0.8-1.0-0.61.7-0.1-1.70.40.31.3-0.9-0.3
Stereotopy head waving bouts, day 70.20.20.30.10.50.60.50.50.50.5-0.50.40.40.30.50.40.50.4
Stereotopy head waving duration, day 70.20.30.7-0.80.40.20.80.60.50.4-0.70.40.50.30.2-0.10.60.5
Locomotion velocity, session 80.40.52.11.50.40.5-0.30.10.00.30.60.6-0.30.90.71.20.00.5
Locomotion distance, session 83.24.710.12.62.32.50.91.81.72.0-0.62.50.72.92.83.21.62.3
Degree of sensitization distance1.61.72.11.01.41.41.11.31.31.3-0.91.41.11.41.41.41.31.4
Degree of sensitization stereotypy0.60.71.00.30.91.00.80.80.90.9-0.80.80.70.61.00.70.90.8
Condit. Reinf. active minus inactive responses2.22.53.6-0.21.71.61.71.71.81.8-1.81.51.91.21.50.91.81.5
Condit. Reinf. active-inactive response ratio1.01.11.50.31.11.21.11.11.21.2-1.21.01.10.71.10.71.21.0
Condit. Reinf. active responses4.04.97.3-0.62.42.12.52.42.62.5-2.52.22.71.82.01.22.52.2
Condit. Reinf. inactive responses1.11.22.1-0.41.21.01.31.21.31.2-1.21.11.50.91.00.61.21.1
Incentive salience index mean1.92.33.0-0.41.61.41.71.71.71.7-1.71.51.71.31.40.91.71.6
Condit. Reinf. lever presses0.20.30.70.20.60.50.40.60.40.5-0.20.70.10.90.60.70.50.7
Time in familiar zone, hab. session 10.20.20.50.3-0.4-0.2-0.3-0.5-0.3-0.30.3-0.50.0-0.7-0.3-0.3-0.3-0.6
Time in novel zone, hab. session 10.10.10.30.00.30.30.20.40.20.2-0.20.40.00.50.30.30.30.4
Total zone transitions, hab. session 10.20.31.71.3-0.00.3-0.6-0.3-0.2-0.10.60.0-0.60.20.40.7-0.3-0.1
Total locomotion distance, hab. session 10.71.02.21.41.01.40.40.80.81.1-0.51.00.31.01.51.50.90.9
Locomotion velocity, hab. session 10.71.12.21.21.11.40.50.80.91.1-0.61.00.21.01.51.50.91.0
Time in familiar zone, hab. session 20.20.21.21.10.00.3-0.5-0.3-0.10.00.4-0.0-0.50.00.40.6-0.2-0.1
Time in novel zone, hab. session 20.10.10.3-0.4-0.3-0.5-0.1-0.1-0.3-0.40.2-0.1-0.1-0.0-0.5-0.4-0.3-0.1
Total zone transitions, hab. session 20.91.13.41.80.91.1-0.00.60.50.80.31.20.01.51.41.80.41.0
Total locomotion distance, hab. session 22.33.15.31.41.92.01.11.71.51.8-0.92.10.92.22.22.31.52.0
Locomotion velocity, hab. session 22.63.55.21.12.12.11.41.91.72.0-1.22.21.22.32.22.31.72.1
Novel to familiar place preference ratio0.80.92.6-0.50.70.61.40.91.20.9-1.60.31.5-0.30.3-0.51.20.4
Novelty place preference0.70.82.4-0.60.60.51.40.81.10.8-1.50.21.5-0.40.2-0.61.10.3
Time in novel zone, NPP test0.70.72.0-0.30.60.51.30.81.00.8-1.40.31.4-0.20.3-0.41.10.4
Total zone transitions, NPP test0.91.44.52.01.01.2-0.20.60.40.80.41.3-0.31.81.52.10.41.1
Total locomotion distance, NPP test2.43.37.22.01.92.00.81.61.31.7-0.52.10.52.52.32.71.42.0
Locomotion velocity, NPP test2.02.95.61.71.81.90.91.51.41.7-0.72.00.72.22.12.41.41.9
Pavlov. Cond. lever latency1.11.48.93.00.61.1-0.80.10.10.60.80.8-0.61.11.42.00.00.5
Pavlov. Cond. magazine entry latency0.71.04.5-2.10.20.01.20.60.80.4-1.5-0.21.5-0.8-0.3-1.20.70.0
Pavlov. Cond. change in total contacts0.60.72.1-1.0-0.7-0.7-0.0-0.6-0.4-0.6-0.2-1.00.0-1.4-0.9-1.4-0.3-1.0
Pavlov. Cond. index score1.21.66.6-2.60.60.21.81.11.20.8-1.90.31.7-0.2-0.1-1.11.20.6
Pavlov. Cond. latency score1.01.38.2-2.90.2-0.31.50.70.80.3-1.6-0.01.4-0.5-0.6-1.50.80.2
Pavlov. Cond. lever contacts0.50.64.6-2.1-0.1-0.50.90.40.2-0.1-0.8-0.20.6-0.4-0.7-1.20.30.0
Pavlov. Cond. magazine entry number0.81.05.52.30.30.4-0.9-0.1-0.40.01.20.7-1.21.30.81.7-0.30.5
Pavlov. Cond. intertrial magazine entries1.11.31.90.91.31.20.81.01.11.2-0.71.30.81.31.31.41.01.2
Pavlov. Cond. lever-magazine prob. diff.1.21.55.6-2.40.70.31.81.11.20.8-2.00.41.7-0.2-0.0-1.01.20.6
Pavlov. Cond. response bias0.81.05.8-2.4-0.1-0.41.10.40.50.1-1.3-0.41.2-1.0-0.7-1.50.5-0.2
Bone: apparent density0.30.60.80.30.80.80.70.80.70.8-0.60.80.50.90.80.70.80.8
Bone surface0.20.30.7-0.80.40.20.80.70.50.4-0.70.40.60.40.1-0.10.60.6
Bone volume0.30.40.7-0.20.70.60.90.80.70.7-0.80.70.60.70.50.30.80.7
Bone: connectivity density0.20.31.20.50.60.40.40.60.30.4-0.10.80.11.10.50.70.40.8
Bone: cortical apparent density2.43.14.80.8-1.8-1.4-2.2-2.0-2.0-1.92.1-1.7-2.1-1.4-1.4-0.8-2.0-1.8
Bone: cortical area3.75.611.6-2.02.21.93.32.62.82.5-3.41.93.01.21.50.22.82.1
Bone: cortical porosity1.21.34.2-1.9-0.9-1.00.2-0.6-0.3-0.6-0.6-1.30.4-1.9-1.3-2.0-0.3-1.2
Bone: cortical porosity0.70.72.4-1.5-0.5-0.50.5-0.20.1-0.2-0.9-0.80.7-1.4-0.8-1.50.1-0.7
Bone: cortical thickness2.23.69.2-2.31.51.12.82.02.21.8-3.01.12.70.30.7-0.62.31.4
Bone: cortical thickness0.80.92.3-0.80.90.91.31.01.21.1-1.50.61.30.20.70.01.20.7
Bone: cortical tissue density2.73.65.60.8-2.0-1.6-2.4-2.2-2.1-2.02.2-1.9-2.3-1.6-1.5-0.8-2.1-2.0
Bone: elastic displacement0.50.61.5-0.70.60.51.20.80.90.7-1.20.41.1-0.00.3-0.31.00.5
Bone: elastic work2.43.18.5-2.41.11.02.61.62.01.5-2.90.62.7-0.40.4-1.02.00.8
Bone: endosteal estimation0.40.92.01.00.91.10.40.80.70.9-0.21.00.31.21.31.40.61.0
Bone: endosteal perimeter0.51.01.8-1.10.90.81.31.11.11.0-1.40.81.10.60.70.21.11.0
Bone: final force3.86.211.5-1.52.52.23.22.83.02.7-3.42.13.11.41.90.72.92.3
Bone: final moment4.06.613.0-1.62.52.33.32.93.12.8-3.62.13.31.31.90.63.02.3
Bone: marrow area0.40.82.01.10.91.10.30.70.70.9-0.21.00.31.21.31.40.60.9
Bone: maximum diameter1.12.04.1-1.61.31.02.01.71.51.4-1.91.21.61.00.80.11.61.4
Bone: maximum force4.17.112.0-1.52.72.43.33.03.22.9-3.52.43.41.72.10.93.12.5
Bone: maximum moment4.37.513.4-1.62.72.53.43.03.33.0-3.72.33.51.62.10.83.22.5
Bone: minimum diameter2.03.67.8-1.41.81.62.62.12.22.1-2.81.52.20.91.40.32.31.7
Bone: periosteal estimation1.83.75.6-0.72.01.82.42.22.22.1-2.41.82.11.51.70.92.21.9
Bone: periosteal perimeter1.42.27.5-2.70.90.62.21.41.51.2-2.40.62.00.00.2-0.91.50.9
Bone: post-yield work0.30.30.90.60.60.60.20.50.40.5-0.10.70.20.90.70.90.40.7
Bone: stiffness0.81.21.6-0.61.21.01.21.21.21.2-1.31.11.30.91.00.61.21.2
Bone: tissue strength2.12.02.50.21.61.41.51.61.51.5-1.41.51.31.41.41.11.61.6
Bone: trabecular number0.00.00.1-0.10.1-0.10.20.20.10.1-0.10.20.10.3-0.00.00.10.2
Bone: trabecular spacing2.73.57.22.22.02.20.91.51.51.9-0.72.10.72.32.52.71.61.9
Bone: trabecular thickness0.70.92.7-1.6-0.8-0.80.1-0.4-0.3-0.6-0.4-1.00.3-1.5-1.1-1.7-0.3-0.9
Bone: trabecular tissue density0.60.91.60.0-1.0-0.8-1.2-1.1-1.1-1.01.2-0.8-1.2-0.6-0.7-0.3-1.2-0.9
Breakpoint value in progressive ratio session0.10.10.60.3-0.00.50.3-0.00.20.2-0.6-0.40.1-0.70.3-0.30.3-0.2
Distance traveled before self-admin0.40.41.2-0.50.40.91.00.60.70.6-1.10.00.7-0.30.4-0.30.80.3
Distance traveled after self-admin1.21.32.41.21.21.50.81.11.11.1-0.91.11.01.01.21.21.21.1
Delta time in closed arm before/after self-admin0.30.31.9-1.40.1-1.20.50.5-0.1-0.0-0.20.20.00.5-0.3-0.3-0.00.1
Delta time in open arm before/after self-admin0.60.52.01.30.61.40.00.40.50.5-0.40.5-0.20.51.01.00.40.5
Diff in mean of infusions in LGA sessions0.20.30.80.0-0.5-0.4-0.6-0.6-0.6-0.60.4-0.6-0.9-0.6-0.3-0.3-0.4-0.5
Extinction: sum of active levers before priming1.51.53.40.9-1.3-0.9-1.3-1.3-1.4-1.41.2-1.4-1.9-1.1-0.9-0.7-1.2-1.3
Active lever presses in extinction session 60.60.61.50.4-0.8-0.6-0.6-0.6-0.8-0.70.2-1.2-1.0-1.1-0.5-0.7-0.7-1.0
Delta distance traveled before/after self-admin0.40.52.81.70.50.6-0.30.30.10.20.30.6-0.20.90.51.20.10.4
Delta ambulatory time before/after self-admin0.40.42.61.6-0.1-0.1-0.8-0.2-0.5-0.30.90.2-0.70.6-0.00.9-0.50.0
Time in closed arm before self-admin0.80.91.90.1-1.0-0.4-1.0-1.4-0.7-0.91.1-1.0-0.5-1.3-0.8-0.9-0.8-1.1
Time in closed arm after self-admin2.93.06.6-1.5-1.9-2.6-1.2-1.7-1.6-1.71.4-1.8-0.9-1.8-2.0-2.1-1.7-1.8
Time in open arm before self-admin0.20.21.2-1.10.2-0.80.40.5-0.1-0.0-0.30.3-0.10.6-0.3-0.10.10.4
Time in open arm after self-admin0.20.30.80.80.50.90.00.40.20.3-0.20.5-0.30.60.50.90.30.5
Sum of active levers in priming session hrs 5-60.30.31.11.00.21.1-0.00.10.60.6-0.6-0.20.6-0.50.80.30.40.0
Time to tail flick, vehicle, before self-admin0.10.10.3-0.20.40.20.40.30.30.4-0.30.40.20.50.30.30.40.5
Time to tail flick, vehicle, after self-admin1.61.72.6-0.2-1.3-1.3-1.6-1.5-1.6-1.51.6-1.0-1.5-0.8-1.4-0.7-1.6-1.2
Time to tail flick, test, before self-admin0.10.10.5-0.6-0.2-0.7-0.0-0.1-0.0-0.1-0.0-0.30.6-0.3-0.4-0.6-0.3-0.4
Time to tail flick, test, after self-admin0.30.31.1-0.4-0.5-1.1-0.2-0.2-0.6-0.50.1-0.5-0.7-0.1-0.6-0.5-0.6-0.5
Delta time to tail flick, vehicle, before/after SA0.10.10.30.5-0.0-0.1-0.4-0.0-0.3-0.20.30.1-0.30.3-0.00.4-0.3-0.0
Delta time to tail flick, test, before/after SA0.70.61.30.3-0.8-0.5-0.7-0.8-0.9-0.90.6-0.9-1.2-0.8-0.7-0.6-0.7-0.8
Ambulatory time before self-admin1.11.12.6-0.50.91.31.51.11.31.1-1.60.51.20.10.9-0.01.40.8
Ambulatory time after self-admin0.70.71.41.00.91.20.70.90.80.8-0.80.80.60.70.90.80.90.9
Total heroin consumption0.20.31.3-0.0-0.5-0.1-0.2-0.4-0.3-0.4-0.4-0.9-0.7-1.2-0.2-0.6-0.2-0.5
Area under the delay curve1.21.32.80.7-1.1-0.5-1.7-1.5-1.3-1.21.5-1.1-1.1-1.2-0.8-0.3-1.3-1.0
Delay disc. indifference point, 0s delay0.00.10.4-0.3-0.00.6-0.3-0.1-0.1-0.1-0.0-0.0-0.3-0.10.10.1-0.00.2
Delay disc. indifference point, 16s delay0.60.63.71.9-0.20.2-1.2-0.2-0.7-0.30.9-0.0-1.00.30.31.1-0.6-0.2
Delay disc. indifference point, 2s delay0.40.41.1-0.2-0.7-0.1-1.0-0.9-0.7-0.60.6-0.7-0.5-1.0-0.5-0.4-0.7-0.5
Delay disc. indifference point, 24s delay5.35.16.70.5-2.4-2.2-2.6-2.5-2.6-2.42.5-2.3-2.5-2.1-2.0-1.3-2.5-2.4
Delay disc. indifference point, 4s delay0.60.71.70.1-0.90.0-0.9-1.3-0.9-0.91.1-0.8-0.3-1.2-0.8-0.6-0.7-0.6
Delay disc. indifference point, 8s delay1.41.52.4-0.2-1.3-0.9-1.3-1.5-1.3-1.31.3-1.3-0.9-1.5-1.2-1.0-1.2-1.3
Delay discount exponential model param2.12.34.1-0.61.60.92.01.91.71.6-1.91.51.41.61.20.61.71.5
Delay discount hyperbolic model param2.02.24.0-0.61.50.82.01.91.71.5-1.81.41.31.61.20.61.61.4
Fecal boli incidents, locomotor time 10.20.30.60.6-0.4-0.4-0.8-0.6-0.6-0.50.5-0.3-0.7-0.4-0.40.0-0.5-0.4
Change in fecal boli incidents, locomotor task3.93.75.5-0.0-2.2-1.4-2.0-2.3-1.9-2.12.0-2.2-1.5-2.1-2.0-1.8-2.0-2.0
Time >=10cm from walls, locomotor time 11.31.32.20.91.21.21.01.01.01.0-0.51.51.01.41.01.11.21.4
Bouts of movement, locomotor time 11.61.73.40.7-1.3-1.3-1.6-1.5-1.4-1.31.9-1.2-1.4-1.0-1.1-0.5-1.5-1.3
Total resting periods, locomotor time 12.42.74.80.4-1.7-1.7-1.8-2.0-1.8-1.72.2-1.6-1.5-1.4-1.5-1.0-1.8-1.7
Rest time, locomotor task time 10.70.81.1-0.7-0.9-0.9-0.6-0.9-0.8-0.80.8-1.0-0.4-1.1-0.9-1.0-0.8-1.0
Distance moved, locomotor task time 10.90.91.30.01.01.21.01.01.00.9-1.01.10.71.00.90.81.11.2
Vertical activity count, locomotor time 12.52.63.80.61.81.51.51.81.61.6-1.71.81.11.81.71.61.81.9
Time >=10cm from walls, locomotor time 20.10.10.9-1.00.00.10.3-0.0-0.0-0.10.00.30.30.2-0.4-0.30.10.3
Bouts of movement, locomotor time 20.70.82.00.9-0.8-0.9-1.3-1.0-1.0-0.91.4-0.6-0.9-0.4-0.60.0-1.0-0.6
Total resting periods, locomotor time 20.30.31.10.8-0.4-0.7-0.9-0.6-0.6-0.51.1-0.2-0.60.0-0.30.3-0.6-0.2
Rest time, locomotor task time 20.20.20.8-0.4-0.4-0.9-0.2-0.5-0.4-0.40.7-0.2-0.0-0.4-0.6-0.4-0.3-0.4
Distance moved, locomotor task time 20.10.10.5-0.60.20.70.20.30.20.2-0.40.3-0.00.40.20.20.10.3
Vertical activity count, locomotor time 20.80.91.80.41.01.10.61.00.80.9-0.81.10.41.31.01.10.71.1
Weight adjusted by age2.12.45.0-1.01.51.51.81.91.81.8-2.21.21.41.31.70.61.61.4
Seeking ratio, delayed vs. immediate footshock1.41.63.1-0.91.21.81.41.41.41.2-1.51.21.50.91.00.51.41.4
Locomotion in novel chamber0.10.10.50.60.20.2-0.30.2-0.10.10.10.2-0.30.60.40.7-0.00.3
Locomotion in novel chamber post-restriction1.31.54.5-0.91.10.91.61.21.51.2-1.31.12.10.70.80.11.51.2
Progressive ratio0.30.40.80.5-0.6-0.5-0.7-0.5-0.7-0.70.4-0.7-0.7-0.4-0.5-0.3-0.7-0.9
Food seeking constrained by brief footshock0.50.61.00.2-0.8-0.6-0.7-1.0-0.7-0.80.6-0.9-0.7-1.0-0.7-0.7-0.7-1.0
Seeking ratio, punishment vs. effort0.10.20.30.10.50.50.40.20.50.5-0.20.50.40.30.40.40.50.6
Run reversals in cocaine runway, females0.60.63.41.80.11.2-0.9-0.2-0.20.10.90.3-0.60.40.51.1-0.20.2
Run reversals in cocaine runway, males0.50.42.3-1.50.1-0.00.90.30.40.2-0.9-0.20.8-0.5-0.2-1.00.50.1
Latency to leave start box in cocaine runway0.10.10.40.7-0.2-0.3-0.5-0.2-0.3-0.20.5-0.0-0.2-0.1-0.10.2-0.3-0.2
Latency to leave start box in cocaine runway, F0.20.20.70.80.30.1-0.30.30.00.20.20.6-0.30.70.40.80.10.4
Latency to leave start box in cocaine runway, M0.10.10.2-0.1-0.2-0.50.0-0.3-0.0-0.10.3-0.20.4-0.3-0.3-0.4-0.1-0.2
Cd content in liver1.01.13.31.8-0.8-0.4-1.4-1.2-1.1-0.81.5-0.7-1.3-0.4-0.20.4-1.1-0.9
Co content in liver0.10.10.60.8-0.10.1-0.3-0.2-0.2-0.10.3-0.1-0.5-0.10.20.3-0.1-0.1
Cu content in liver0.50.72.2-1.1-0.7-0.80.2-0.5-0.3-0.5-0.3-0.90.2-1.4-1.0-1.5-0.2-0.9
Fe content in liver0.50.61.50.7-0.7-0.5-1.2-0.9-0.9-0.71.1-0.6-1.2-0.3-0.30.1-0.9-0.6
K content in liver2.82.83.9-0.51.81.42.01.91.81.8-1.71.81.51.71.51.11.81.9
Mg content in liver1.61.73.80.71.41.11.01.31.11.2-0.61.70.71.91.41.51.11.6
Mn content in liver0.10.20.7-0.80.3-0.10.60.30.40.2-0.60.30.60.2-0.1-0.30.40.3
Na content in liver0.00.00.4-0.6-0.1-0.20.20.1-0.1-0.1-0.1-0.1-0.1-0.0-0.2-0.3-0.00.0
Rb content in liver1.72.22.70.71.61.51.41.41.51.6-1.21.61.41.51.61.41.51.6
Se content in liver0.40.50.70.30.70.70.80.70.70.7-0.70.70.70.60.60.50.80.7
Sr content in liver1.91.73.5-1.0-1.4-1.3-0.8-1.2-1.1-1.30.5-1.6-0.7-1.9-1.6-1.7-1.1-1.5
Zn content in liver0.50.52.2-1.5-0.6-1.0-0.0-0.4-0.5-0.60.2-0.4-0.1-0.4-1.1-1.1-0.4-0.4