Mcrip1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	intron excision ratio	chr10:105822705:105828028	0.06	0.04	2.4e-03	0.03	0.03	0.03	0.03	1.2e-02	8.7e-03	6.8e-03	1.6e-02
2	Liver	alternative TSS	ENSRNOT00000054960	0.13	0.08	1.1e-12	0.12	0.12	0.12	0.12	1.2e-13	8.6e-13	8.2e-13	6.3e-13
3	Liver	alternative TSS	ENSRNOT00000103843	0.13	0.08	3.2e-12	0.12	0.11	0.12	0.11	2.9e-13	3.1e-12	6.4e-13	1.5e-12
4	Liver	gene expression	ENSRNOG00000036691	0.44	0.15	0.0e+00	0.39	0.4	0.39	0.39	2.2e-46	8.0e-47	2.2e-46	1.7e-46
5	Liver	intron excision ratio	chr10:105822705:105828028	0.02	0.02	5.7e-03	0.02	0.02	0.03	0.03	1.6e-03	2.4e-03	4.3e-04	6.9e-04
6	Liver	mRNA stability	ENSRNOG00000036691	0.04	0.03	2.2e-04	0.01	0.02	0.02	0.02	7.2e-03	1.4e-03	1.2e-03	2.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6
BMI with tail	0.6	1.8	2.7	-1.7	1.5	-1.5	1.5	0.5	1.0
BMI without tail	5.1	10.6	13.7	-3.7	3.6	-3.6	3.6	0.9	3.1
Body weight	4.8	20.1	26.8	-5.2	4.8	-4.8	4.7	-2.5	4.5
Epididymis fat weight	1.3	3.1	5.0	-2.2	1.9	-1.9	1.8	-0.3	1.7
Glucose	4.3	6.6	10.6	3.1	-2.6	2.6	-2.4	-0.2	-3.3
Heart weight	0.2	0.4	0.5	-0.7	0.7	-0.7	0.7	0.0	0.4
Left kidney weight	0.2	0.6	2.0	-0.4	0.4	-0.4	0.4	-1.4	0.8
Right kidney weight	0.1	0.2	0.9	-0.4	-0.0	0.0	0.0	-0.9	0.6
Tail length	6.4	19.5	24.4	-4.9	4.7	-4.7	4.6	-1.9	4.9
Length with tail	3.8	13.8	16.3	-4.0	3.6	-3.6	3.5	-3.5	4.0
Length without tail	0.6	1.2	7.1	0.0	-0.4	0.4	-0.3	-2.7	-0.0
Liver weight, left	0.2	0.3	0.5	0.4	-0.4	0.4	-0.3	-0.7	-0.7
Liver weight, right	3.3	5.6	6.8	-2.5	2.2	-2.2	2.1	-2.5	2.6
Parametrial fat weight	2.2	4.3	6.2	-2.5	2.1	-2.1	2.1	-1.6	2.1
Retroperitoneal fat weight	5.3	17.4	23.1	-4.8	4.5	-4.5	4.5	-2.0	4.0
Intraocular pressure	0.5	0.7	0.9	-0.8	1.0	-1.0	0.8	0.2	0.9
Extensor digitorum longus weight	0.2	0.7	2.7	-0.9	0.6	-0.6	0.4	1.6	0.3
Soleus weight	1.7	4.9	6.2	-2.3	2.3	-2.3	2.2	-1.5	2.5
Tibialis anterior weight	0.1	0.2	0.4	-0.6	0.3	-0.3	0.2	0.3	0.5
Tibia length	9.8	27.5	29.8	-4.9	5.2	-5.2	5.5	-5.4	5.2
Number of licking bursts	0.3	0.3	0.7	-0.7	0.5	-0.5	0.5	-0.3	0.8
Food consumed during 24 hour testing period	0.7	0.8	1.5	-1.0	0.9	-0.9	0.8	-0.4	1.2
Times rat made contact with spout	1.2	1.4	3.2	-1.0	0.9	-0.9	1.1	-1.8	1.1
Mean time between licks in bursts	1.6	2.2	2.5	1.6	-1.6	1.6	-1.6	1.3	-1.3
Mean num. licks in bursts	0.1	0.1	0.3	-0.0	0.2	-0.2	0.3	-0.5	0.0
Std. dev. time between licks in bursts	1.3	1.6	2.2	-1.4	1.1	-1.1	0.8	1.5	1.5
Water consumed over 24 hours	0.2	0.2	0.9	0.1	-0.3	0.3	-0.1	-1.0	-0.2
Indifference point 0 sec	0.1	0.1	0.2	-0.3	0.3	-0.3	0.5	0.3	0.1
Indifference point AUC	0.0	0.0	0.1	0.1	-0.1	0.1	-0.2	0.3	0.0
Indifference point function ln k	0.8	1.1	1.3	1.1	-1.0	1.0	-1.0	1.1	-1.1
Indifference point function log k	0.8	1.1	1.3	1.1	-1.0	1.0	-1.0	1.1	-1.1
Delay discounting total patch changes 0 sec	0.1	0.1	0.4	-0.2	0.4	-0.4	0.4	0.6	0.0
Delay discounting total patch changes 12 sec	0.0	0.0	0.0	0.1	-0.1	0.1	0.1	0.1	-0.1
Delay discounting total patch changes 18 sec	0.4	0.6	3.1	0.0	-0.0	0.0	-0.3	1.8	-0.4
Delay discounting total patch changes 24 sec	0.7	0.9	1.4	-1.2	1.1	-1.1	1.0	0.1	0.8
Delay discounting total patch changes 6 sec	0.3	0.5	0.7	-0.5	0.6	-0.6	0.8	-0.8	0.8
Delay discounting time to switch 0 sec	0.4	0.6	0.8	0.9	-0.8	0.8	-0.8	0.2	-0.8
Delay discounting water rate 0 sec	2.1	3.4	4.7	-2.0	2.2	-2.2	2.0	0.0	1.7
Delay discounting water rate 12 sec	0.4	0.6	1.8	-0.6	0.7	-0.7	0.4	1.4	0.3
Delay discounting water rate 18 sec	0.9	1.3	1.8	-1.4	1.3	-1.3	1.0	0.5	1.1
Delay discounting water rate 24 sec	2.4	3.3	4.5	-1.9	2.1	-2.1	1.7	1.5	1.3
Delay discounting water rate 6 sec	0.2	0.3	0.7	-0.8	0.5	-0.5	0.3	0.4	0.5
Locomotor activity	0.6	1.0	1.2	0.9	-1.0	1.0	-1.0	0.9	-1.1
Locomotor testing distance	0.6	0.9	1.8	0.9	-0.7	0.7	-1.1	1.3	-1.0
Locomotor testing rearing	0.3	0.4	1.4	0.5	-0.2	0.2	-0.6	1.2	-0.5
Light reinforcement 1	1.3	2.4	3.2	-1.7	1.8	-1.8	1.5	0.1	1.6
Light reinforcement 2	2.8	3.7	4.6	-2.1	2.1	-2.1	2.0	-0.9	2.1
Reaction time number correct	1.3	1.9	9.1	-0.9	0.8	-0.8	0.2	3.0	0.6
Reaction time mean minus median	0.2	0.2	0.8	0.3	-0.3	0.3	-0.2	-0.9	-0.3
Reaction time mean minus median AUC	0.2	0.2	1.0	-0.4	0.2	-0.2	0.1	-1.0	0.5
Reaction time num false alarms	0.4	0.6	1.8	1.3	-0.6	0.6	-0.6	0.6	-0.8
Reaction time num false alarms AUC	0.7	1.0	2.3	1.5	-0.8	0.8	-0.9	0.8	-0.9
Reaction time trials correct on left	1.3	1.9	9.1	-0.9	0.8	-0.8	0.2	3.0	0.6
Reaction time trials on left	1.4	2.0	9.2	-0.9	0.9	-0.9	0.2	3.0	0.6
Reaction time mean	0.3	0.4	0.6	-0.8	0.8	-0.8	0.6	0.0	0.5
Reaction time mean AUC	0.4	0.5	0.7	-0.8	0.8	-0.8	0.6	0.3	0.6
Median of all reaction times	0.3	0.5	0.7	-0.8	0.8	-0.8	0.7	0.4	0.5
Reaction time omissions	0.4	0.5	0.8	-0.6	0.9	-0.9	0.5	0.2	0.7
Reaction time false alarm rate	1.1	1.5	3.4	1.9	-1.2	1.2	-0.9	-0.7	-1.2
Reaction time premature initiation rate	1.7	2.2	3.4	1.9	-1.4	1.4	-1.5	1.2	-1.5
Reaction time premature initiations	1.4	2.0	6.9	1.2	-0.8	0.8	-1.2	2.6	-1.0
Std. dev. reaction times	0.2	0.3	0.4	0.5	-0.5	0.5	-0.6	0.5	-0.6
Reaction time trials completed	1.4	2.0	9.2	-0.9	0.9	-0.9	0.2	3.0	0.6
Reaction time trials AUC	1.4	2.0	8.9	-1.0	0.9	-0.9	0.3	3.0	0.6
Social response proportion	0.4	0.4	0.9	0.5	-0.5	0.5	-0.7	0.9	-0.5
Social responses	0.0	0.0	0.0	-0.2	-0.1	0.1	-0.2	0.2	-0.1
Social time	0.1	0.1	0.2	0.3	-0.3	0.3	-0.2	0.5	-0.2
Conditioned locomotion	5.0	5.9	8.0	-2.8	2.7	-2.7	2.5	-0.7	2.6
Cocaine response after cond. corrected	0.2	0.3	0.6	0.8	-0.3	0.3	-0.3	0.3	-0.7
Cocaine response after cond. not corrected	0.8	0.9	1.5	1.2	-0.9	0.9	-0.8	0.5	-1.1
Cocaine response before conditioning	0.5	0.6	0.9	0.7	-0.9	0.9	-1.0	0.5	-0.5
Saline control response	3.5	4.6	5.5	-2.3	2.2	-2.2	2.3	-1.4	2.3
Condit. Reinf. active minus inactive responses	1.0	1.2	1.7	-1.3	1.1	-1.1	1.0	-0.7	1.3
Condit. Reinf. active-inactive response ratio	2.4	2.6	2.9	-1.7	1.5	-1.5	1.5	-1.6	1.7
Condit. Reinf. active responses	0.2	0.3	0.4	-0.6	0.6	-0.6	0.4	0.3	0.5
Condit. Reinf. inactive responses	0.7	0.9	2.1	0.8	-0.7	0.7	-0.9	1.5	-1.0
Condit. Reinf. lever presses	0.3	0.4	0.9	-0.5	0.7	-0.7	0.4	0.9	0.3
Condit. Reinf. lever reinforcers received	0.3	0.4	0.8	-0.5	0.7	-0.7	0.4	0.9	0.3
Pavlov. Cond. lever latency	0.7	1.0	1.4	1.1	-1.2	1.2	-0.8	-1.0	-0.7
Pavlov. Cond. magazine entry latency	2.0	2.3	5.6	1.3	-1.2	1.2	-1.4	2.4	-1.4
Pavlov. Cond. change in total contacts	0.5	0.8	3.8	0.3	-0.1	0.1	-0.4	2.0	-0.7
Pavlov. Cond. index score	0.5	0.7	3.4	0.3	0.0	-0.0	-0.3	1.8	-0.6
Pavlov. Cond. latency score	0.5	0.6	3.3	0.1	0.1	-0.1	-0.2	1.8	-0.4
Pavlov. Cond. lever contacts	1.0	1.4	1.9	-1.4	1.4	-1.4	1.0	1.0	1.0
Pavlov. Cond. magazine entry number	1.5	1.8	5.5	-1.0	0.8	-0.8	1.1	-2.3	1.2
Pavlov. Cond. intertrial magazine entries	1.9	2.4	3.1	-1.8	1.6	-1.6	1.5	-1.0	1.7
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	4.1	0.5	-0.1	0.1	-0.5	2.0	-0.8
Pavlov. Cond. response bias	0.4	0.5	2.2	-0.5	0.5	-0.5	0.2	1.5	0.1
Conditioned reinforcement - actives	0.1	0.1	0.3	-0.2	0.5	-0.5	0.2	-0.1	0.3
Conditioned reinforcement - inactives	1.9	2.1	2.7	-1.4	1.6	-1.6	1.4	-1.2	1.4
Conditioned locomotion	0.5	0.6	0.7	-0.8	0.8	-0.8	0.5	-0.8	0.7
Intermittent access intake day 1-15 change	0.7	0.6	0.9	-0.7	0.8	-0.8	0.9	-0.8	0.8
Intermittent access intake escalation	0.6	0.6	0.8	-0.6	0.9	-0.9	0.9	-0.6	0.8
Intermittent access intake escalation 2	1.8	1.8	2.4	-1.0	1.4	-1.4	1.5	-1.5	1.1
Intermitt. access day 1 inactive lever presses	1.2	1.3	1.7	-1.3	1.2	-1.2	1.2	-0.6	1.2
Intermitt. access day 15 inactive lever presses	2.0	2.2	3.1	-1.6	1.8	-1.8	1.3	-0.6	1.6
Intermitt. access escalation Index	1.6	1.5	2.3	-1.3	1.4	-1.4	1.0	-0.2	1.5
Intermittent access day 1 total infusions	0.2	0.2	0.4	-0.6	0.5	-0.5	0.6	-0.0	0.3
Intermittent access day 15 total infusions	0.7	0.8	1.1	-0.9	1.1	-1.1	1.0	-0.4	0.8
Intermittent access terminal intake (last 3 days)	1.4	1.5	1.9	-1.2	1.4	-1.4	1.3	-1.0	1.0
Intermittent access total infusions	0.5	0.6	0.8	-0.8	0.9	-0.9	0.9	-0.4	0.7
Intermittent access day 1 locomotion	0.7	0.7	1.0	-0.9	0.9	-0.9	0.7	-0.2	1.0
Intermittent access day 15 total locomotion	0.6	0.6	0.8	-0.7	0.7	-0.7	0.8	-0.9	0.8
Intermittent access total locomotion	0.8	0.9	1.1	-1.0	1.0	-1.0	0.9	-0.8	1.0
Intermittent access standard deviation	0.5	0.6	1.0	1.0	-0.7	0.7	-0.4	-0.6	-1.0
Cocaine induced anxiety	3.5	4.1	5.4	-1.9	2.1	-2.1	2.3	-2.0	1.4
Post-drug Anxiety	0.2	0.2	0.4	-0.4	0.5	-0.5	0.6	-0.6	0.2
Baseline Anxiety	6.9	7.3	9.5	2.9	-2.9	2.9	-3.1	1.9	-2.4
Lifetime Intake	0.2	0.2	0.3	-0.4	0.5	-0.5	0.5	-0.3	0.4
Incentive Sensitization - Responses	0.2	0.2	0.5	-0.5	0.3	-0.3	0.4	-0.6	0.7
Incentive Sensitization - Breakpoint	0.2	0.2	0.4	-0.4	0.2	-0.2	0.3	-0.7	0.6
Progressive ratio test 1 active lever presses	1.4	1.4	1.8	-1.4	1.3	-1.3	1.3	-0.5	1.3
Progressive ratio test 1 breakpoint	1.7	1.8	2.3	-1.5	1.4	-1.4	1.4	-0.6	1.5
Progressive ratio test 1 inactive lever presses	3.1	3.3	4.4	-2.1	2.1	-2.1	1.9	-0.5	1.8
Progressive ratio test 2 active lever presses	0.5	0.6	0.7	-0.7	0.7	-0.7	0.7	-0.8	0.8
Progressive ratio test 2 breakpoint	0.7	0.7	1.1	-0.9	0.8	-0.8	0.8	-0.7	1.1
Progressive ratio test 2 inactive lever presses	0.5	0.5	0.7	-0.6	0.9	-0.9	0.7	-0.8	0.5
Total sessions with >9 infusions	0.1	0.1	0.2	0.3	-0.3	0.3	-0.5	-0.4	-0.1
Short access day 1 total inactive lever presses	0.2	0.2	0.4	-0.5	0.5	-0.5	0.1	0.3	0.7
Short access day 10 total inactive lever presses	3.2	3.5	4.1	-2.0	1.9	-1.9	2.0	-1.4	2.0
Short access day 1 total infusions	1.4	1.5	1.9	1.2	-1.2	1.2	-1.4	0.5	-1.4
Short access day 10 total infusions	0.5	0.5	0.7	-0.6	0.7	-0.7	0.9	-0.7	0.7
Short access total infusions	0.0	0.0	0.1	0.1	-0.0	0.0	0.0	-0.3	-0.2
Short access day 1 locomotion	0.5	0.5	0.6	0.7	-0.8	0.8	-0.6	-0.7	-0.6
Short access day 10 total locomotion	0.2	0.2	0.9	0.2	-0.4	0.4	-0.2	-1.0	-0.2
Short access total locomotion	0.5	0.5	0.9	0.5	-0.8	0.8	-0.6	-1.0	-0.4
Compulsive drug intake	0.7	0.7	1.0	-0.8	0.9	-0.9	0.7	0.2	1.0
One hour access (0.3 mA shock)	1.5	1.7	2.3	-1.4	1.4	-1.4	1.4	-0.6	1.5
One hour access (shock baseline)	0.3	0.3	0.5	-0.5	0.5	-0.5	0.5	-0.7	0.7
Number of responses in last shaping day	2.3	2.3	3.0	-1.7	1.6	-1.6	1.2	-1.2	1.7
Context. condit. distance diff. score	0.9	1.1	1.8	-1.1	1.0	-1.0	0.7	1.3	0.8
Locomotion velocity, session 1	2.9	3.1	4.0	1.9	-2.0	2.0	-1.9	-0.1	-2.0
Locomotion distance, session 1	2.6	3.4	4.4	1.7	-1.8	1.8	-1.9	2.1	-1.7
Locomotion velocity, session 2	5.0	5.8	7.4	2.6	-2.7	2.7	-2.6	0.9	-2.3
Locomotion distance, session 2	0.4	0.6	1.7	0.5	-0.6	0.6	-0.8	1.3	-0.4
Locomotion velocity, session 3	2.0	2.4	3.2	1.6	-1.7	1.7	-1.6	0.6	-1.8
Locomotion distance, session 3	3.7	4.0	4.6	2.1	-2.1	2.1	-2.0	1.5	-2.1
Stereotopy head waving bouts, day 3	0.8	0.9	1.9	1.4	-1.0	1.0	-0.9	0.0	-0.9
Stereotopy head waving duration, day 3	0.4	0.5	1.0	1.0	-0.7	0.7	-0.7	0.2	-0.6
Locomotion velocity, session 7	0.7	0.8	0.9	0.9	-0.9	0.9	-0.9	0.8	-1.0
Locomotion distance, session 7	3.0	3.8	6.8	1.6	-1.7	1.7	-2.0	2.6	-1.9
Stereotopy head waving bouts, day 7	0.1	0.1	0.2	-0.1	0.5	-0.5	0.5	0.1	0.3
Stereotopy head waving duration, day 7	0.4	0.5	0.6	-0.6	0.7	-0.7	0.8	-0.7	0.8
Locomotion velocity, session 8	0.5	0.6	2.1	0.6	-0.6	0.6	-0.8	1.4	-0.4
Locomotion distance, session 8	0.9	1.3	5.7	-0.9	0.6	-0.6	0.3	2.4	0.6
Degree of sensitization distance	0.7	0.7	1.1	-1.1	0.9	-0.9	0.7	0.2	0.9
Degree of sensitization stereotypy	0.4	0.4	0.7	-0.6	0.8	-0.8	0.8	0.1	0.5
Condit. Reinf. active minus inactive responses	2.4	2.7	3.2	-1.7	1.8	-1.8	1.8	-0.8	1.7
Condit. Reinf. active-inactive response ratio	1.0	1.1	1.4	-1.2	1.2	-1.2	1.2	-0.4	0.9
Condit. Reinf. active responses	4.4	5.4	6.3	-2.4	2.5	-2.5	2.5	-1.3	2.5
Condit. Reinf. inactive responses	1.0	1.2	1.5	-1.1	1.2	-1.2	1.2	-0.6	1.2
Incentive salience index mean	2.1	2.6	3.1	-1.7	1.7	-1.7	1.7	-0.9	1.8
Condit. Reinf. lever presses	0.1	0.1	0.2	-0.3	0.2	-0.2	0.2	0.2	0.4
Time in familiar zone, hab. session 1	0.1	0.1	0.3	0.2	-0.3	0.3	-0.3	-0.1	-0.5
Time in novel zone, hab. session 1	0.0	0.0	0.1	-0.0	0.2	-0.2	0.1	0.3	0.3
Total zone transitions, hab. session 1	0.5	0.7	1.7	0.8	-0.6	0.6	-0.7	1.3	-0.9
Total locomotion distance, hab. session 1	0.2	0.3	1.0	-0.1	0.5	-0.5	0.4	1.0	0.0
Locomotion velocity, hab. session 1	0.2	0.3	0.9	-0.3	0.6	-0.6	0.4	1.0	0.1
Time in familiar zone, hab. session 2	0.4	0.4	1.0	0.3	-0.4	0.4	-0.5	1.0	-0.7
Time in novel zone, hab. session 2	0.1	0.1	0.1	0.3	-0.2	0.2	-0.2	-0.2	0.1
Total zone transitions, hab. session 2	0.5	0.6	3.3	0.0	-0.3	0.3	-0.5	1.8	-0.2
Total locomotion distance, hab. session 2	0.7	0.9	1.5	-1.0	0.9	-0.9	0.7	1.2	1.0
Locomotion velocity, hab. session 2	0.9	1.3	1.5	-1.2	1.2	-1.2	1.0	0.9	1.2
Novel to familiar place preference ratio	2.2	2.3	3.1	-1.1	1.6	-1.6	1.8	-1.6	1.2
Novelty place preference	2.1	2.2	2.9	-1.1	1.5	-1.5	1.7	-1.7	1.2
Time in novel zone, NPP test	1.7	1.8	2.3	-1.0	1.4	-1.4	1.5	-1.4	1.1
Total zone transitions, NPP test	0.7	1.0	4.8	0.1	-0.4	0.4	-0.7	2.2	-0.3
Total locomotion distance, NPP test	0.6	0.8	3.5	-0.6	0.5	-0.5	0.2	1.9	0.6
Locomotion velocity, NPP test	0.5	0.7	2.3	-0.7	0.7	-0.7	0.5	1.5	0.7
Pavlov. Cond. lever latency	1.4	1.8	6.4	0.9	-0.8	0.8	-1.0	2.5	-1.2
Pavlov. Cond. magazine entry latency	2.1	2.7	5.0	-1.4	1.5	-1.5	1.7	-2.2	1.3
Pavlov. Cond. change in total contacts	0.2	0.2	1.1	0.0	0.2	-0.2	0.4	-1.1	-0.1
Pavlov. Cond. index score	3.4	4.4	6.6	-2.0	1.9	-1.9	2.1	-2.6	2.0
Pavlov. Cond. latency score	2.8	3.6	7.3	-1.6	1.6	-1.6	1.8	-2.7	1.8
Pavlov. Cond. lever contacts	1.1	1.3	3.3	-0.9	0.8	-0.8	1.0	-1.8	1.1
Pavlov. Cond. magazine entry number	1.7	2.1	5.7	1.1	-1.2	1.2	-1.5	2.4	-0.9
Pavlov. Cond. intertrial magazine entries	0.3	0.4	0.6	-0.8	0.7	-0.7	0.5	0.4	0.7
Pavlov. Cond. lever-magazine prob. diff.	3.5	4.4	6.3	-2.0	2.0	-2.0	2.1	-2.5	2.0
Pavlov. Cond. response bias	2.0	2.4	5.8	-1.2	1.3	-1.3	1.5	-2.4	1.2
Bone: apparent density	0.2	0.4	0.7	-0.8	0.6	-0.6	0.6	0.0	0.7
Bone surface	0.4	0.7	0.9	-0.9	0.7	-0.7	0.8	-0.9	1.0
Bone volume	0.3	0.6	0.9	-0.9	0.8	-0.8	0.8	-0.4	0.8
Bone: connectivity density	0.1	0.1	0.3	-0.4	0.1	-0.1	0.0	0.2	0.5
Bone: cortical apparent density	3.0	4.0	5.1	2.0	-2.1	2.1	-2.0	1.3	-2.3
Bone: cortical area	7.1	10.8	12.7	-3.2	3.4	-3.4	3.6	-2.7	3.3
Bone: cortical porosity	0.9	1.0	4.3	-0.2	0.6	-0.6	0.8	-2.1	0.2
Bone: cortical porosity	1.0	1.1	3.5	-0.4	0.9	-0.9	1.0	-1.9	0.5
Bone: cortical thickness	5.6	9.2	10.7	-2.8	3.0	-3.0	3.3	-3.2	2.9
Bone: cortical thickness	1.6	1.9	2.6	-1.2	1.5	-1.5	1.6	-1.2	1.2
Bone: cortical tissue density	3.5	4.6	5.8	2.2	-2.2	2.2	-2.2	1.4	-2.4
Bone: elastic displacement	1.4	1.6	2.1	-1.1	1.2	-1.2	1.4	-1.3	1.1
Bone: elastic work	6.6	8.6	10.8	-2.6	2.9	-2.9	3.3	-3.3	2.5
Bone: endosteal estimation	0.1	0.3	1.5	-0.4	0.2	-0.2	0.1	1.2	0.1
Bone: endosteal perimeter	0.9	1.8	2.1	-1.4	1.4	-1.4	1.4	-1.1	1.3
Bone: final force	5.9	9.7	11.8	-3.1	3.4	-3.4	3.4	-2.0	3.1
Bone: final moment	6.6	10.9	13.6	-3.2	3.6	-3.6	3.7	-2.3	3.2
Bone: marrow area	0.1	0.3	1.6	-0.4	0.2	-0.2	0.1	1.3	0.1
Bone: maximum diameter	2.1	3.8	4.5	-1.9	1.9	-1.9	2.0	-1.7	2.1
Bone: maximum force	5.9	10.3	12.1	-3.4	3.5	-3.5	3.5	-1.9	3.2
Bone: maximum moment	6.6	11.5	13.9	-3.5	3.7	-3.7	3.7	-2.2	3.3
Bone: minimum diameter	3.7	6.7	8.7	-2.4	2.8	-2.8	2.9	-2.0	2.6
Bone: periosteal estimation	2.3	4.8	5.7	-2.4	2.4	-2.4	2.4	-1.1	2.2
Bone: periosteal perimeter	3.7	6.2	8.6	-2.3	2.4	-2.4	2.6	-2.9	2.4
Bone: post-yield work	0.1	0.1	0.4	-0.1	0.1	-0.1	-0.1	0.7	0.1
Bone: stiffness	0.9	1.4	1.8	-1.4	1.3	-1.3	1.2	-0.4	1.3
Bone: tissue strength	1.7	1.7	2.2	-1.4	1.4	-1.4	1.4	-0.3	1.5
Bone: trabecular number	0.1	0.1	0.2	-0.5	0.1	-0.1	0.1	-0.3	0.4
Bone: trabecular spacing	0.7	0.9	3.3	-0.6	0.7	-0.7	0.5	1.8	0.5
Bone: trabecular thickness	0.5	0.6	2.8	-0.1	0.4	-0.4	0.6	-1.7	0.2
Bone: trabecular tissue density	1.0	1.4	1.7	1.3	-1.2	1.2	-1.2	0.8	-1.2
Breakpoint value in progressive ratio session	0.2	0.2	0.4	-0.0	0.6	-0.6	0.6	0.1	-0.4
Distance traveled before self-admin	0.9	1.0	1.6	-0.9	1.1	-1.1	1.3	-1.1	0.3
Distance traveled after self-admin	0.6	0.7	0.8	-0.9	0.9	-0.9	0.8	0.9	0.5
Delta time in closed arm before/after self-admin	0.6	0.6	1.5	-0.7	0.2	-0.2	-0.0	-1.2	1.2
Delta time in open arm before/after self-admin	0.5	0.4	1.7	0.2	0.4	-0.4	0.1	1.3	-0.7
Diff in mean of infusions in LGA sessions	0.2	0.3	0.5	0.6	-0.4	0.4	-0.4	0.4	-0.7
Extinction: sum of active levers before priming	1.5	1.5	3.0	1.2	-1.2	1.2	-1.2	0.7	-1.7
Active lever presses in extinction session 6	0.3	0.3	1.2	0.6	-0.2	0.2	-0.3	0.2	-1.1
Delta distance traveled before/after self-admin	0.6	0.7	3.2	0.3	-0.3	0.3	-0.6	1.8	-0.3
Delta ambulatory time before/after self-admin	1.1	1.2	3.3	0.9	-0.9	0.9	-1.2	1.8	-0.7
Time in closed arm before self-admin	0.7	0.8	1.4	1.2	-1.1	1.1	-0.4	0.2	-1.1
Time in closed arm after self-admin	1.2	1.2	1.9	0.9	-1.4	1.4	-0.9	-1.3	-0.3
Time in open arm before self-admin	0.3	0.3	0.8	-0.6	0.3	-0.3	-0.1	-0.7	0.9
Time in open arm after self-admin	0.2	0.2	1.1	0.1	0.2	-0.2	-0.2	1.1	-0.5
Sum of active levers in priming session hrs 5-6	0.4	0.4	1.1	0.3	0.6	-0.6	0.7	1.0	-0.5
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.3	-0.3	0.3	-0.3	0.3	0.2	0.6
Time to tail flick, vehicle, after self-admin	1.8	2.0	2.7	1.5	-1.6	1.6	-1.6	0.3	-1.3
Time to tail flick, test, before self-admin	0.1	0.1	0.3	-0.1	0.0	-0.0	0.1	-0.5	0.5
Time to tail flick, test, after self-admin	0.1	0.1	0.2	0.1	-0.1	0.1	-0.5	-0.4	-0.0
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.3	0.2	-0.3	0.3	-0.6	0.2	-0.3
Delta time to tail flick, test, before/after SA	0.6	0.5	1.3	0.7	-0.6	0.6	-0.7	0.2	-1.1
Ambulatory time before self-admin	1.9	2.0	3.2	-1.3	1.6	-1.6	1.8	-1.1	0.8
Ambulatory time after self-admin	0.4	0.4	0.7	-0.6	0.8	-0.8	0.7	0.5	0.4
Total heroin consumption	0.1	0.2	0.4	0.2	0.4	-0.4	0.2	-0.3	-0.7
Area under the delay curve	2.4	2.6	3.6	1.7	-1.5	1.5	-1.6	1.3	-1.9
Delay disc. indifference point, 0s delay	0.1	0.1	0.5	0.2	0.0	-0.0	-0.2	0.2	-0.7
Delay disc. indifference point, 16s delay	2.0	2.0	5.3	1.1	-0.9	0.9	-1.5	2.3	-1.4
Delay disc. indifference point, 2s delay	0.5	0.6	1.4	0.9	-0.6	0.6	-0.7	0.5	-1.2
Delay disc. indifference point, 24s delay	5.8	5.6	7.5	2.7	-2.5	2.5	-2.5	1.1	-2.5
Delay disc. indifference point, 4s delay	1.1	1.2	2.2	1.2	-1.1	1.1	-0.8	0.5	-1.5
Delay disc. indifference point, 8s delay	1.4	1.5	2.1	1.4	-1.3	1.3	-1.2	0.3	-1.5
Delay discount exponential model param	3.4	3.6	5.0	-2.0	1.9	-1.9	1.9	-1.3	2.2
Delay discount hyperbolic model param	3.3	3.5	5.0	-2.0	1.8	-1.8	1.8	-1.3	2.2
Fecal boli incidents, locomotor time 1	0.3	0.4	0.6	0.6	-0.5	0.5	-0.8	0.5	-0.7
Change in fecal boli incidents, locomotor task	3.5	3.3	4.8	2.2	-2.0	2.0	-1.5	0.5	-2.2
Time >=10cm from walls, locomotor time 1	0.5	0.5	1.2	-0.9	0.5	-0.5	0.6	0.3	1.1
Bouts of movement, locomotor time 1	2.3	2.6	3.4	1.7	-1.9	1.9	-1.6	0.9	-1.6
Total resting periods, locomotor time 1	2.9	3.2	4.8	1.9	-2.2	2.2	-1.7	0.7	-1.7
Rest time, locomotor task time 1	0.4	0.4	0.6	0.4	-0.8	0.8	-0.4	-0.5	-0.7
Distance moved, locomotor task time 1	0.7	0.7	1.1	-1.1	1.0	-1.0	0.8	-0.1	0.8
Vertical activity count, locomotor time 1	2.0	2.0	3.0	-1.7	1.7	-1.7	1.2	-0.1	1.5
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.7	-0.1	-0.0	0.0	0.1	-0.8	0.4
Bouts of movement, locomotor time 2	1.4	1.5	2.0	1.2	-1.4	1.4	-1.4	1.0	-0.9
Total resting periods, locomotor time 2	0.8	0.9	1.2	0.8	-1.1	1.1	-1.1	0.9	-0.5
Rest time, locomotor task time 2	0.2	0.2	0.5	-0.0	-0.7	0.7	-0.3	-0.4	0.1
Distance moved, locomotor task time 2	0.1	0.1	0.2	-0.4	0.4	-0.4	0.2	-0.1	-0.2
Vertical activity count, locomotor time 2	0.3	0.4	0.6	-0.8	0.8	-0.8	0.3	0.4	0.5
Weight adjusted by age	3.2	3.6	5.0	-1.9	2.2	-2.2	2.1	-1.3	1.4
Seeking ratio, delayed vs. immediate footshock	1.6	1.8	2.3	-1.3	1.5	-1.5	1.5	-0.9	1.2
Locomotion in novel chamber	0.1	0.2	0.6	-0.0	-0.1	0.1	-0.5	0.8	-0.4
Locomotion in novel chamber post-restriction	2.0	2.4	4.1	-1.5	1.3	-1.3	1.7	-1.4	2.0
Progressive ratio	0.4	0.4	0.7	0.8	-0.4	0.4	-0.8	0.4	-0.9
Food seeking constrained by brief footshock	0.2	0.3	0.7	0.3	-0.6	0.6	-0.5	-0.1	-0.8
Seeking ratio, punishment vs. effort	0.1	0.1	0.3	-0.6	0.2	-0.2	0.4	0.1	0.4
Run reversals in cocaine runway, females	1.9	1.9	5.4	1.1	-0.9	0.9	-0.9	2.3	-1.5
Run reversals in cocaine runway, males	1.3	1.2	3.3	-0.9	0.9	-0.9	1.2	-1.8	0.7
Latency to leave start box in cocaine runway	0.2	0.2	0.4	0.5	-0.5	0.5	-0.5	0.6	-0.2
Latency to leave start box in cocaine runway, F	0.2	0.2	0.9	0.4	-0.2	0.2	-0.4	0.9	0.1
Latency to leave start box in cocaine runway, M	0.1	0.1	0.3	-0.1	-0.3	0.3	0.1	-0.6	0.3
Cd content in liver	2.3	2.5	2.9	1.4	-1.5	1.5	-1.6	1.7	-1.7
Co content in liver	0.2	0.2	0.6	0.3	-0.3	0.3	-0.3	0.8	-0.4
Cu content in liver	0.4	0.5	2.3	-0.3	0.3	-0.3	0.6	-1.5	0.4
Fe content in liver	0.9	1.1	1.2	0.8	-1.1	1.1	-1.1	1.0	-1.1
K content in liver	2.9	2.9	4.7	-1.8	1.7	-1.7	1.7	-0.7	2.2
Mg content in liver	0.6	0.6	1.4	-0.9	0.6	-0.6	0.5	0.5	1.2
Mn content in liver	0.4	0.5	0.9	-0.6	0.6	-0.6	0.6	-0.9	0.8
Na content in liver	0.1	0.1	0.2	-0.3	0.1	-0.1	0.1	-0.5	0.2
Rb content in liver	1.0	1.2	1.6	-1.3	1.2	-1.2	1.1	0.2	1.3
Se content in liver	0.3	0.4	0.5	-0.6	0.7	-0.7	0.7	-0.3	0.7
Sr content in liver	0.7	0.7	1.4	1.2	-0.5	0.5	-0.4	-1.1	-0.9
Zn content in liver	0.3	0.3	1.6	0.1	-0.2	0.2	-0.1	-1.3	0.6