Hub : Genes

ENSRNOG00000036686

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	ENSRNOG00000036686	0.09	0.06	3.8e-04	0.05	0.05	0.05	0.04	1.6e-03	1.0e-03	9.2e-04	2.7e-03
2	Liver	gene expression	ENSRNOG00000036686	0.23	0.12	9.2e-12	0.11	0.1	0.1	0.1	4.9e-12	4.3e-11	8.8e-11	6.1e-11
3	Liver	mRNA stability	ENSRNOG00000036686	0.11	0.07	4.1e-10	0.09	0.09	0.08	0.09	2.9e-10	8.0e-10	2.6e-09	1.1e-09
4	PL	gene expression	ENSRNOG00000036686	0.1	0.06	1.3e-06	0.07	0.08	0.08	0.09	8.8e-06	6.8e-07	1.3e-06	3.8e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
BMI with tail	0.8	2.7	5.4	-0.2	1.5	1.7	-2.3
BMI without tail	6.4	13.3	23.1	-0.6	3.6	4.1	-4.8
Body weight	4.4	18.7	22.9	-3.5	4.8	4.6	-4.3
Epididymis fat weight	1.4	3.3	5.2	-0.8	1.9	1.9	-2.3
Glucose	3.7	5.7	9.2	0.0	-2.6	-2.6	3.0
Heart weight	0.4	0.6	0.9	-0.5	0.7	0.9	-1.0
Left kidney weight	0.1	0.4	1.3	-1.2	0.4	0.2	0.4
Right kidney weight	0.1	0.4	1.2	-1.1	-0.0	-0.0	0.5
Tail length	6.0	18.2	22.2	-3.0	4.7	4.7	-4.4
Length with tail	2.9	10.8	14.0	-3.7	3.6	3.3	-2.3
Length without tail	0.9	2.0	3.6	-1.9	-0.4	-0.8	1.8
Liver weight, left	0.2	0.3	0.5	-0.6	-0.4	-0.5	0.7
Liver weight, right	2.1	3.4	4.6	-2.1	2.2	1.8	-1.1
Parametrial fat weight	2.1	4.2	4.4	-2.1	2.1	2.1	-1.9
Retroperitoneal fat weight	5.2	17.1	20.7	-2.8	4.5	4.6	-4.4
Intraocular pressure	0.5	0.7	0.9	-0.5	1.0	0.8	-0.9
Extensor digitorum longus weight	0.3	1.2	2.8	1.1	0.6	0.7	-1.7
Soleus weight	1.5	4.3	5.3	-1.7	2.3	2.3	-2.0
Tibialis anterior weight	0.0	0.1	0.2	0.4	0.3	0.4	-0.5
Tibia length	9.2	26.0	36.8	-6.1	5.2	5.2	-3.5
Number of licking bursts	0.2	0.2	0.3	0.2	0.5	0.6	-0.5
Food consumed during 24 hour testing period	1.0	1.2	2.9	-1.7	0.9	0.8	-0.8
Times rat made contact with spout	1.6	1.9	5.8	-2.4	0.9	0.9	-0.2
Mean time between licks in bursts	1.7	2.4	3.0	1.7	-1.6	-1.6	1.3
Mean num. licks in bursts	0.5	0.6	2.2	-1.5	0.2	0.1	0.1
Std. dev. time between licks in bursts	1.5	1.8	4.3	0.7	1.1	1.1	-2.1
Water consumed over 24 hours	0.7	0.9	2.6	-1.6	-0.3	-0.3	0.9
Indifference point 0 sec	0.1	0.2	0.3	0.5	0.3	0.4	-0.5
Indifference point AUC	0.0	0.0	0.0	-0.0	-0.1	-0.1	-0.1
Indifference point function ln k	0.7	1.0	1.8	1.3	-1.0	-1.0	0.7
Indifference point function log k	0.7	1.0	1.8	1.3	-1.0	-1.0	0.7
Delay discounting total patch changes 0 sec	0.2	0.3	0.5	0.7	0.4	0.4	-0.6
Delay discounting total patch changes 12 sec	0.0	0.0	0.0	0.1	-0.1	-0.0	0.1
Delay discounting total patch changes 18 sec	0.5	0.7	2.4	1.5	-0.0	-0.2	-0.6
Delay discounting total patch changes 24 sec	0.7	0.9	1.5	-0.0	1.1	0.9	-1.2
Delay discounting total patch changes 6 sec	0.2	0.3	0.4	-0.7	0.6	0.6	-0.3
Delay discounting time to switch 0 sec	0.4	0.7	1.1	0.4	-0.8	-0.9	1.0
Delay discounting water rate 0 sec	2.4	3.8	5.7	-0.6	2.2	2.1	-2.4
Delay discounting water rate 12 sec	0.5	0.7	1.6	0.6	0.7	0.6	-1.3
Delay discounting water rate 18 sec	1.0	1.3	2.3	0.2	1.3	1.2	-1.5
Delay discounting water rate 24 sec	3.0	4.1	8.4	0.2	2.1	1.9	-2.9
Delay discounting water rate 6 sec	0.1	0.2	0.4	0.1	0.5	0.4	-0.6
Locomotor activity	0.5	0.8	1.0	0.8	-1.0	-1.0	0.8
Locomotor testing distance	0.5	0.8	1.2	1.1	-0.7	-1.1	0.4
Locomotor testing rearing	0.2	0.4	1.1	1.0	-0.2	-0.6	-0.0
Light reinforcement 1	1.5	2.8	4.4	-0.3	1.8	1.9	-2.1
Light reinforcement 2	2.8	3.7	4.8	-1.4	2.1	2.2	-2.0
Reaction time number correct	1.6	2.3	3.9	1.9	0.8	0.8	-2.0
Reaction time mean minus median	0.2	0.3	0.8	-0.5	-0.3	-0.4	0.9
Reaction time mean minus median AUC	0.2	0.2	0.7	-0.8	0.2	-0.0	0.5
Reaction time num false alarms	0.2	0.3	0.6	0.8	-0.6	-0.5	0.3
Reaction time num false alarms AUC	0.5	0.8	1.1	1.1	-0.8	-0.9	0.6
Reaction time trials correct on left	1.6	2.3	3.9	1.9	0.8	0.8	-2.0
Reaction time trials on left	1.6	2.3	4.0	2.0	0.9	0.8	-2.0
Reaction time mean	0.4	0.5	0.6	-0.6	0.8	0.7	-0.8
Reaction time mean AUC	0.4	0.5	0.8	-0.4	0.8	0.7	-0.9
Median of all reaction times	0.5	0.6	1.1	-0.4	0.8	0.8	-1.0
Reaction time omissions	0.3	0.4	0.8	0.4	0.9	0.5	-0.6
Reaction time false alarm rate	0.9	1.3	2.4	0.1	-1.2	-1.2	1.5
Reaction time premature initiation rate	1.5	2.1	2.7	1.6	-1.4	-1.6	1.0
Reaction time premature initiations	1.3	1.9	6.0	2.4	-0.8	-0.9	-0.2
Std. dev. reaction times	0.2	0.2	0.3	0.4	-0.5	-0.6	0.5
Reaction time trials completed	1.6	2.3	4.0	2.0	0.9	0.8	-2.0
Reaction time trials AUC	1.7	2.4	4.2	1.9	0.9	0.9	-2.1
Social response proportion	0.4	0.5	1.0	1.0	-0.5	-0.7	0.5
Social responses	0.1	0.1	0.4	0.6	-0.1	-0.1	0.1
Social time	0.1	0.1	0.3	0.5	-0.3	-0.1	0.3
Conditioned locomotion	4.9	5.8	7.2	-1.4	2.7	2.6	-2.7
Cocaine response after cond. corrected	0.1	0.1	0.1	0.3	-0.3	-0.4	0.4
Cocaine response after cond. not corrected	0.7	0.7	0.9	0.6	-0.9	-0.9	1.0
Cocaine response before conditioning	0.7	0.9	0.9	0.9	-0.9	-0.9	1.0
Saline control response	3.3	4.4	5.1	-1.9	2.2	2.3	-2.0
Condit. Reinf. active minus inactive responses	1.0	1.2	1.4	-1.2	1.1	1.0	-1.0
Condit. Reinf. active-inactive response ratio	2.5	2.6	4.8	-2.2	1.5	1.5	-1.0
Condit. Reinf. active responses	0.3	0.4	0.7	-0.3	0.6	0.5	-0.9
Condit. Reinf. inactive responses	0.5	0.6	1.5	1.2	-0.7	-0.7	0.1
Condit. Reinf. lever presses	0.5	0.6	1.7	0.3	0.7	0.5	-1.3
Condit. Reinf. lever reinforcers received	0.4	0.6	1.5	0.1	0.7	0.5	-1.2
Pavlov. Cond. lever latency	1.1	1.6	3.7	-0.4	-1.2	-1.0	1.9
Pavlov. Cond. magazine entry latency	1.8	2.0	5.2	2.3	-1.2	-1.2	0.0
Pavlov. Cond. change in total contacts	0.6	0.8	2.2	1.5	-0.1	-0.2	-1.0
Pavlov. Cond. index score	0.6	0.8	2.0	1.4	0.0	-0.2	-1.1
Pavlov. Cond. latency score	0.6	0.8	1.9	1.4	0.1	-0.1	-1.1
Pavlov. Cond. lever contacts	1.4	2.0	4.5	0.3	1.4	1.3	-2.1
Pavlov. Cond. magazine entry number	1.4	1.7	5.0	-2.2	0.8	1.0	0.2
Pavlov. Cond. intertrial magazine entries	1.7	2.2	2.5	-1.5	1.6	1.6	-1.2
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	2.5	1.6	-0.1	-0.3	-1.0
Pavlov. Cond. response bias	0.6	0.8	2.0	0.9	0.5	0.4	-1.4
Conditioned reinforcement - actives	0.3	0.3	0.5	0.7	0.5	0.2	-0.4
Conditioned reinforcement - inactives	1.5	1.7	2.7	-1.1	1.6	1.1	-1.2
Conditioned locomotion	0.2	0.3	0.6	-0.4	0.8	0.2	-0.4
Intermittent access intake day 1-15 change	0.6	0.6	0.7	-0.8	0.8	0.8	-0.7
Intermittent access intake escalation	0.6	0.6	0.8	-0.6	0.9	0.8	-0.7
Intermittent access intake escalation 2	1.4	1.4	2.0	-1.1	1.4	1.2	-0.9
Intermitt. access day 1 inactive lever presses	1.5	1.6	3.1	-1.7	1.2	1.0	-0.9
Intermitt. access day 15 inactive lever presses	1.7	1.8	3.1	-0.4	1.8	1.3	-1.5
Intermitt. access escalation Index	1.3	1.2	1.9	-0.1	1.4	1.1	-1.2
Intermittent access day 1 total infusions	0.3	0.3	0.5	-0.4	0.5	0.7	-0.7
Intermittent access day 15 total infusions	0.8	0.9	1.1	-0.5	1.1	1.0	-1.0
Intermittent access terminal intake (last 3 days)	1.2	1.3	1.9	-0.8	1.4	1.2	-1.1
Intermittent access total infusions	0.6	0.6	0.8	-0.5	0.9	0.9	-0.9
Intermittent access day 1 locomotion	0.6	0.6	0.9	-0.5	0.9	0.6	-0.9
Intermittent access day 15 total locomotion	0.6	0.6	1.7	-1.3	0.7	0.5	-0.3
Intermittent access total locomotion	0.7	0.8	1.5	-1.2	1.0	0.6	-0.7
Intermittent access standard deviation	0.4	0.5	1.0	-0.3	-0.7	-0.6	1.0
Cocaine induced anxiety	3.5	4.0	4.6	-2.1	2.1	1.9	-1.7
Post-drug Anxiety	0.2	0.2	0.3	-0.5	0.5	0.4	-0.5
Baseline Anxiety	7.4	7.8	8.6	2.7	-2.9	-2.9	2.6
Lifetime Intake	0.2	0.2	0.3	-0.4	0.5	0.4	-0.4
Incentive Sensitization - Responses	0.3	0.3	0.9	-0.9	0.3	0.3	-0.1
Incentive Sensitization - Breakpoint	0.2	0.2	0.8	-0.9	0.2	0.2	0.0
Progressive ratio test 1 active lever presses	1.4	1.4	1.7	-0.9	1.3	1.3	-1.3
Progressive ratio test 1 breakpoint	1.8	1.8	2.2	-1.1	1.4	1.5	-1.4
Progressive ratio test 1 inactive lever presses	3.5	3.7	4.4	-1.5	2.1	2.0	-2.0
Progressive ratio test 2 active lever presses	0.4	0.5	0.9	-1.0	0.7	0.5	-0.4
Progressive ratio test 2 breakpoint	0.5	0.6	0.7	-0.9	0.8	0.7	-0.6
Progressive ratio test 2 inactive lever presses	0.4	0.5	0.7	-0.6	0.9	0.6	-0.6
Total sessions with >9 infusions	0.2	0.2	0.3	0.0	-0.3	-0.5	0.5
Short access day 1 total inactive lever presses	0.1	0.1	0.3	0.2	0.5	-0.0	-0.3
Short access day 10 total inactive lever presses	3.6	4.0	6.5	-2.5	1.9	1.9	-1.5
Short access day 1 total infusions	1.5	1.6	2.3	1.0	-1.2	-1.5	1.2
Short access day 10 total infusions	0.4	0.5	0.6	-0.8	0.7	0.7	-0.5
Short access total infusions	0.0	0.0	0.1	-0.3	-0.0	-0.1	0.0
Short access day 1 locomotion	0.5	0.6	1.2	0.1	-0.8	-0.7	1.1
Short access day 10 total locomotion	0.5	0.5	0.8	-0.9	-0.4	-0.6	0.9
Short access total locomotion	0.9	0.9	1.6	-0.7	-0.8	-0.9	1.3
Compulsive drug intake	0.6	0.6	0.9	-0.2	0.9	0.9	-0.9
One hour access (0.3 mA shock)	1.4	1.6	2.2	-0.7	1.4	1.5	-1.4
One hour access (shock baseline)	0.2	0.2	0.3	-0.3	0.5	0.5	-0.4
Number of responses in last shaping day	1.6	1.6	2.7	-1.1	1.6	1.0	-1.3
Context. condit. distance diff. score	1.2	1.5	3.5	0.7	1.0	1.0	-1.9
Locomotion velocity, session 1	3.0	3.3	5.0	0.4	-2.0	-2.0	2.2
Locomotion distance, session 1	2.5	3.2	5.2	2.3	-1.8	-1.8	0.9
Locomotion velocity, session 2	5.3	6.2	7.4	1.7	-2.7	-2.7	2.7
Locomotion distance, session 2	0.5	0.6	1.7	1.3	-0.6	-0.6	-0.1
Locomotion velocity, session 3	1.9	2.2	2.8	0.9	-1.7	-1.7	1.6
Locomotion distance, session 3	3.4	3.7	4.3	1.8	-2.1	-2.1	1.7
Stereotopy head waving bouts, day 3	0.7	0.9	1.7	0.1	-1.0	-1.0	1.3
Stereotopy head waving duration, day 3	0.4	0.5	0.8	0.3	-0.7	-0.7	0.9
Locomotion velocity, session 7	0.7	0.8	1.6	1.3	-0.9	-0.9	0.5
Locomotion distance, session 7	2.6	3.3	6.9	2.6	-1.7	-1.7	0.5
Stereotopy head waving bouts, day 7	0.2	0.2	0.2	0.2	0.5	0.5	-0.5
Stereotopy head waving duration, day 7	0.3	0.4	0.6	-0.5	0.7	0.7	-0.3
Locomotion velocity, session 8	0.6	0.7	2.2	1.5	-0.6	-0.6	-0.1
Locomotion distance, session 8	1.4	2.1	4.5	1.8	0.6	0.6	-2.1
Degree of sensitization distance	0.9	0.9	2.0	-0.1	0.9	0.9	-1.4
Degree of sensitization stereotypy	0.5	0.6	0.8	0.1	0.8	0.8	-0.9
Condit. Reinf. active minus inactive responses	2.4	2.7	3.2	-1.1	1.8	1.8	-1.8
Condit. Reinf. active-inactive response ratio	1.1	1.2	1.6	-0.6	1.2	1.2	-1.3
Condit. Reinf. active responses	4.4	5.3	6.3	-1.7	2.5	2.5	-2.4
Condit. Reinf. inactive responses	1.1	1.3	1.5	-0.9	1.2	1.2	-1.2
Incentive salience index mean	1.9	2.3	2.9	-0.9	1.7	1.7	-1.6
Condit. Reinf. lever presses	0.1	0.1	0.2	0.5	0.2	0.2	-0.4
Time in familiar zone, hab. session 1	0.1	0.1	0.1	-0.3	-0.3	-0.3	0.2
Time in novel zone, hab. session 1	0.1	0.1	0.1	0.3	0.2	0.2	-0.2
Total zone transitions, hab. session 1	0.3	0.5	1.2	1.1	-0.6	-0.6	-0.1
Total locomotion distance, hab. session 1	0.6	0.9	1.8	1.1	0.5	0.5	-1.3
Locomotion velocity, hab. session 1	0.7	1.0	1.9	1.1	0.6	0.6	-1.4
Time in familiar zone, hab. session 2	0.4	0.4	1.2	1.1	-0.4	-0.4	-0.2
Time in novel zone, hab. session 2	0.1	0.1	0.3	-0.4	-0.2	-0.2	0.6
Total zone transitions, hab. session 2	0.6	0.8	2.5	1.6	-0.3	-0.3	-0.7
Total locomotion distance, hab. session 2	1.0	1.3	2.7	1.0	0.9	0.9	-1.6
Locomotion velocity, hab. session 2	1.2	1.7	3.4	0.7	1.2	1.2	-1.9
Novel to familiar place preference ratio	2.2	2.3	2.8	-1.7	1.6	1.6	-1.0
Novelty place preference	2.1	2.1	2.9	-1.7	1.5	1.5	-0.9
Time in novel zone, NPP test	1.7	1.8	2.2	-1.5	1.4	1.4	-0.9
Total zone transitions, NPP test	0.8	1.1	3.5	1.9	-0.4	-0.4	-0.8
Total locomotion distance, NPP test	1.0	1.4	2.6	1.5	0.5	0.5	-1.6
Locomotion velocity, NPP test	0.9	1.3	2.7	1.2	0.7	0.7	-1.7
Pavlov. Cond. lever latency	1.3	1.6	4.8	2.2	-0.8	-0.8	-0.7
Pavlov. Cond. magazine entry latency	2.0	2.6	5.5	-2.4	1.5	1.5	-0.6
Pavlov. Cond. change in total contacts	0.3	0.3	0.9	-0.9	0.2	0.2	0.4
Pavlov. Cond. index score	2.8	3.6	6.4	-2.5	1.9	1.9	-0.8
Pavlov. Cond. latency score	2.3	2.9	6.4	-2.5	1.6	1.6	-0.3
Pavlov. Cond. lever contacts	0.8	0.9	2.3	-1.5	0.8	0.8	0.2
Pavlov. Cond. magazine entry number	1.9	2.3	6.3	2.5	-1.2	-1.2	0.2
Pavlov. Cond. intertrial magazine entries	0.5	0.6	1.3	0.2	0.7	0.7	-1.1
Pavlov. Cond. lever-magazine prob. diff.	3.0	3.7	6.5	-2.5	2.0	2.0	-0.9
Pavlov. Cond. response bias	1.8	2.3	5.7	-2.4	1.3	1.3	-0.2
Bone: apparent density	0.2	0.4	0.7	0.0	0.6	0.7	-0.9
Bone surface	0.2	0.4	0.6	-0.7	0.7	0.8	-0.4
Bone volume	0.3	0.5	0.7	-0.3	0.8	0.8	-0.7
Bone: connectivity density	0.0	0.0	0.1	0.3	0.1	0.1	-0.3
Bone: cortical apparent density	2.5	3.3	4.3	1.3	-2.1	-2.1	1.7
Bone: cortical area	6.1	9.2	11.8	-2.7	3.4	3.4	-2.5
Bone: cortical porosity	1.1	1.2	3.9	-2.0	0.6	0.5	0.3
Bone: cortical porosity	1.1	1.1	3.2	-1.8	0.9	0.8	-0.0
Bone: cortical thickness	4.8	8.0	9.3	-3.0	3.0	3.1	-2.0
Bone: cortical thickness	1.7	1.9	2.3	-1.3	1.5	1.5	-1.2
Bone: cortical tissue density	2.9	3.8	5.0	1.4	-2.2	-2.2	1.8
Bone: elastic displacement	1.3	1.4	1.8	-1.3	1.2	1.3	-0.8
Bone: elastic work	6.2	8.1	11.1	-3.3	2.9	3.1	-1.9
Bone: endosteal estimation	0.1	0.3	0.6	0.8	0.2	0.3	-0.7
Bone: endosteal perimeter	0.7	1.4	1.9	-0.9	1.4	1.4	-1.0
Bone: final force	5.6	9.2	11.5	-2.5	3.4	3.4	-2.8
Bone: final moment	6.4	10.5	13.0	-2.7	3.6	3.6	-3.0
Bone: marrow area	0.1	0.3	0.6	0.8	0.2	0.2	-0.7
Bone: maximum diameter	1.5	2.8	3.9	-1.3	1.9	2.0	-1.3
Bone: maximum force	5.8	10.1	12.1	-2.7	3.5	3.5	-3.0
Bone: maximum moment	6.5	11.3	13.5	-2.9	3.7	3.7	-3.2
Bone: minimum diameter	3.0	5.6	7.8	-1.7	2.8	2.8	-2.0
Bone: periosteal estimation	2.1	4.3	5.7	-1.3	2.4	2.4	-2.0
Bone: periosteal perimeter	3.0	4.9	6.9	-2.6	2.4	2.4	-1.2
Bone: post-yield work	0.1	0.1	0.3	0.5	0.1	0.0	-0.5
Bone: stiffness	0.8	1.3	1.6	-0.9	1.3	1.2	-1.2
Bone: tissue strength	1.8	1.7	2.7	-0.5	1.4	1.4	-1.6
Bone: trabecular number	0.0	0.0	0.1	-0.3	0.1	0.1	-0.1
Bone: trabecular spacing	1.2	1.6	3.0	1.5	0.7	0.7	-1.7
Bone: trabecular thickness	0.6	0.7	2.3	-1.5	0.4	0.4	0.4
Bone: trabecular tissue density	0.9	1.2	1.5	0.9	-1.2	-1.2	1.0
Breakpoint value in progressive ratio session	0.1	0.2	0.3	-0.3	0.6	0.4	-0.4
Distance traveled before self-admin	0.8	0.9	1.3	-0.6	1.1	1.1	-0.7
Distance traveled after self-admin	0.8	0.9	1.7	0.4	0.9	1.0	-1.3
Delta time in closed arm before/after self-admin	0.2	0.2	0.4	-0.6	0.2	-0.2	0.3
Delta time in open arm before/after self-admin	0.4	0.4	0.7	0.8	0.4	0.3	-0.7
Diff in mean of infusions in LGA sessions	0.3	0.3	0.5	0.7	-0.4	-0.5	0.5
Extinction: sum of active levers before priming	1.0	1.0	1.5	0.3	-1.2	-1.2	1.1
Active lever presses in extinction session 6	0.2	0.2	0.5	-0.0	-0.2	-0.7	0.5
Delta distance traveled before/after self-admin	0.5	0.5	1.7	1.3	-0.3	-0.3	-0.4
Delta ambulatory time before/after self-admin	1.0	1.1	2.6	1.6	-0.9	-1.0	0.3
Time in closed arm before self-admin	0.4	0.4	1.2	-0.1	-1.1	-0.3	0.6
Time in closed arm after self-admin	1.8	1.9	2.8	-1.2	-1.4	-1.1	1.7
Time in open arm before self-admin	0.1	0.1	0.1	-0.2	0.3	-0.3	0.3
Time in open arm after self-admin	0.2	0.2	0.8	0.9	0.2	-0.0	-0.3
Sum of active levers in priming session hrs 5-6	0.6	0.6	0.9	0.9	0.6	0.5	-0.9
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.1	-0.4	0.3	0.3	0.1
Time to tail flick, vehicle, after self-admin	2.1	2.2	2.6	1.1	-1.6	-1.6	1.6
Time to tail flick, test, before self-admin	0.2	0.2	0.6	-0.8	0.0	-0.1	0.1
Time to tail flick, test, after self-admin	0.3	0.3	0.6	0.1	-0.1	-0.8	0.7
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.8	0.9	-0.3	-0.6	0.0
Delta time to tail flick, test, before/after SA	0.7	0.6	0.9	0.8	-0.6	-0.8	0.9
Ambulatory time before self-admin	2.0	2.0	2.8	-1.1	1.6	1.7	-1.2
Ambulatory time after self-admin	0.5	0.5	0.8	0.2	0.8	0.8	-0.9
Total heroin consumption	0.0	0.0	0.1	0.1	0.4	-0.0	0.2
Area under the delay curve	1.7	1.9	2.4	1.1	-1.5	-1.5	1.2
Delay disc. indifference point, 0s delay	0.0	0.0	0.0	0.2	0.0	-0.2	-0.1
Delay disc. indifference point, 16s delay	1.5	1.5	3.6	1.9	-0.9	-1.2	0.3
Delay disc. indifference point, 2s delay	0.4	0.4	0.8	0.3	-0.6	-0.9	0.7
Delay disc. indifference point, 24s delay	5.8	5.6	7.0	1.6	-2.5	-2.6	2.6
Delay disc. indifference point, 4s delay	0.6	0.6	1.2	0.1	-1.1	-0.8	0.8
Delay disc. indifference point, 8s delay	1.3	1.3	1.9	0.5	-1.3	-1.2	1.4
Delay discount exponential model param	2.7	2.8	3.6	-1.2	1.9	1.9	-1.7
Delay discount hyperbolic model param	2.5	2.7	3.4	-1.1	1.8	1.8	-1.6
Fecal boli incidents, locomotor time 1	0.4	0.4	0.7	0.5	-0.5	-0.9	0.6
Change in fecal boli incidents, locomotor task	3.3	3.1	4.4	1.3	-2.0	-1.5	2.1
Time >=10cm from walls, locomotor time 1	0.6	0.6	1.5	-0.1	0.5	1.2	-0.9
Bouts of movement, locomotor time 1	2.0	2.2	3.4	1.4	-1.9	-1.5	1.1
Total resting periods, locomotor time 1	2.5	2.8	4.8	1.1	-2.2	-1.7	1.5
Rest time, locomotor task time 1	0.5	0.6	0.8	-0.5	-0.8	-0.7	0.9
Distance moved, locomotor task time 1	0.9	1.0	1.5	-0.4	1.0	1.1	-1.2
Vertical activity count, locomotor time 1	2.2	2.3	3.6	-0.8	1.7	1.5	-1.9
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.2	-0.5	-0.0	0.1	0.4
Bouts of movement, locomotor time 2	1.2	1.3	2.0	0.9	-1.4	-1.3	0.8
Total resting periods, locomotor time 2	0.7	0.8	1.1	0.9	-1.1	-1.0	0.4
Rest time, locomotor task time 2	0.2	0.3	0.5	-0.5	-0.7	-0.2	0.6
Distance moved, locomotor task time 2	0.1	0.1	0.2	-0.1	0.4	0.1	-0.4
Vertical activity count, locomotor time 2	0.4	0.4	0.8	-0.0	0.8	0.4	-0.9
Weight adjusted by age	3.1	3.5	5.0	-1.1	2.2	2.0	-2.0
Seeking ratio, delayed vs. immediate footshock	1.5	1.7	2.4	0.0	1.5	1.5	-1.5
Locomotion in novel chamber	0.1	0.1	0.3	0.6	-0.1	-0.3	-0.0
Locomotion in novel chamber post-restriction	2.0	2.4	3.7	-1.7	1.3	1.9	-1.2
Progressive ratio	0.5	0.6	0.9	0.8	-0.4	-0.9	0.8
Food seeking constrained by brief footshock	0.2	0.2	0.3	-0.6	-0.6	-0.5	0.4
Seeking ratio, punishment vs. effort	0.3	0.4	0.6	-0.7	0.2	0.6	-0.8
Run reversals in cocaine runway, females	0.9	0.9	2.5	1.6	-0.9	-0.4	-0.0
Run reversals in cocaine runway, males	0.7	0.6	1.1	-1.1	0.9	0.8	-0.1
Latency to leave start box in cocaine runway	0.2	0.2	0.3	0.2	-0.5	-0.5	0.4
Latency to leave start box in cocaine runway, F	0.2	0.2	0.8	0.9	-0.2	-0.4	-0.0
Latency to leave start box in cocaine runway, M	0.4	0.4	1.4	-1.2	-0.3	0.1	0.2
Cd content in liver	1.5	1.6	2.3	1.0	-1.5	-1.5	0.8
Co content in liver	0.0	0.0	0.1	0.1	-0.3	-0.3	-0.0
Cu content in liver	0.9	1.1	4.1	-2.0	0.3	0.3	0.3
Fe content in liver	0.8	1.0	1.2	1.1	-1.1	-1.1	0.6
K content in liver	2.3	2.3	3.0	-1.1	1.7	1.7	-1.5
Mg content in liver	0.4	0.4	0.6	0.3	0.6	0.6	-0.8
Mn content in liver	0.2	0.3	0.5	-0.7	0.6	0.6	-0.0
Na content in liver	0.0	0.0	0.1	-0.3	0.1	0.1	0.1
Rb content in liver	0.9	1.2	1.8	-0.1	1.2	1.2	-1.3
Se content in liver	0.3	0.3	0.5	0.2	0.7	0.7	-0.6
Sr content in liver	0.5	0.5	0.9	0.6	-0.5	-0.5	0.9
Zn content in liver	0.4	0.4	0.9	-0.9	-0.2	-0.2	0.9