Pcyt2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000036684 0.07 0.06 3.8e-04 0.02 0.03 0.03 0.03 1.0e-03 1.8e-04 3.3e-04 4.2e-04
2 BLA isoform ratio ENSRNOT00000054952 0.08 0.06 4.2e-03 0.06 0.01 0.03 0.03 4.9e-04 1.3e-01 9.4e-03 9.8e-03
3 Brain intron excision ratio chr10:105891315:105892120 0.19 0.13 9.0e-08 0.08 0.09 0.08 0.09 3.5e-08 1.6e-08 8.3e-08 1.4e-08
4 Brain intron excision ratio chr10:105891801:105892120 0.15 0.14 6.1e-05 0.05 0.05 0.04 0.06 1.0e-05 1.7e-05 1.1e-04 4.6e-06
5 Liver gene expression ENSRNOG00000036684 0.04 0.03 9.8e-04 0.03 0.02 0.02 0.02 5.8e-04 2.2e-03 1.7e-03 1.6e-03
6 Liver intron excision ratio chr10:105891315:105892120 0.12 0.08 3.6e-07 0.06 0.07 0.06 0.06 1.4e-07 7.8e-08 3.6e-07 2.1e-07
7 Liver intron excision ratio chr10:105893820:105894322 0.16 0.08 0.0e+00 0.17 0.16 0.17 0.17 6.7e-19 7.8e-18 1.4e-18 1.7e-18
8 Liver intron excision ratio chr10:105893861:105894322 0.15 0.08 5.6e-17 0.16 0.16 0.16 0.16 9.1e-18 6.6e-17 1.9e-17 2.0e-17
9 Liver mRNA stability ENSRNOG00000036684 0.12 0.07 2.7e-09 0.04 0.07 0.06 0.06 1.6e-05 1.6e-08 1.2e-07 9.1e-08
10 NAcc gene expression ENSRNOG00000036684 0.08 0.07 5.5e-04 0.02 0.02 0.04 0.01 5.8e-03 1.2e-02 9.6e-04 2.9e-02
11 NAcc intron excision ratio chr10:105891315:105891748 0.05 0.04 9.5e-04 0.04 0.03 0.04 0.03 5.8e-04 2.8e-03 6.6e-04 1.7e-03
12 NAcc intron excision ratio chr10:105891315:105892120 0.04 0.03 3.4e-03 0.03 0.03 0.04 0.04 2.3e-03 1.9e-03 3.2e-04 5.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.62.05.7-1.30.51.1-1.02.41.5-1.71.71.91.0-0.40.9
BMI without tail5.210.825.1-3.00.42.8-2.55.03.4-4.14.14.62.8-0.72.8
Body weight4.016.722.5-4.52.14.7-4.73.24.6-4.64.64.14.5-2.63.7
Epididymis fat weight1.12.54.2-1.60.51.7-1.62.01.8-1.91.92.01.6-0.40.9
Glucose3.35.014.61.81.4-2.22.1-2.6-2.22.6-2.6-3.8-1.8-1.4-0.7
Heart weight0.30.50.8-0.70.30.6-0.40.90.7-0.90.90.50.5-0.70.8
Left kidney weight0.10.41.2-0.60.10.8-0.9-1.10.5-0.20.2-0.10.6-0.70.3
Right kidney weight0.10.21.3-0.1-0.70.4-0.6-1.20.10.0-0.0-0.10.0-0.1-0.2
Tail length5.416.222.3-4.11.34.5-4.53.64.3-4.74.74.74.4-1.83.9
Length with tail2.810.217.6-3.62.04.1-4.20.93.5-3.33.32.53.8-2.43.1
Length without tail0.61.48.1-0.20.90.5-0.7-2.9-0.10.8-0.8-1.80.3-1.3-0.0
Liver weight, left0.20.31.30.00.6-0.20.1-1.0-0.20.5-0.5-1.1-0.2-0.90.1
Liver weight, right2.33.87.4-2.11.42.6-2.70.12.1-1.81.81.62.5-1.41.6
Parametrial fat weight1.83.44.8-2.01.62.2-2.21.22.1-2.12.11.71.8-1.21.8
Retroperitoneal fat weight4.615.220.7-4.32.74.3-4.13.54.5-4.64.64.04.0-2.03.3
Intraocular pressure0.40.61.5-0.70.10.7-0.51.20.7-0.80.81.10.7-0.40.9
Extensor digitorum longus weight0.21.05.3-0.0-1.1-0.00.22.30.3-0.70.71.6-0.21.2-0.2
Soleus weight1.33.95.5-2.11.42.3-2.31.12.2-2.32.32.12.2-1.11.8
Tibialis anterior weight0.00.10.6-0.0-0.50.2-0.10.50.2-0.40.40.80.10.5-0.1
Tibia length9.226.035.8-5.85.15.9-6.01.25.6-5.25.23.25.5-4.95.4
Number of licking bursts0.20.30.7-0.4-0.20.6-0.60.20.5-0.60.60.80.30.80.1
Food consumed during 24 hour testing period0.70.92.9-0.81.00.7-0.80.90.8-0.80.80.80.9-1.70.7
Times rat made contact with spout1.71.96.8-1.41.81.2-1.3-0.21.2-0.90.90.11.4-2.61.7
Mean time between licks in bursts1.62.22.71.6-1.5-1.61.6-0.8-1.61.6-1.6-1.1-1.61.5-1.6
Mean num. licks in bursts0.50.64.8-0.51.10.2-0.20.10.4-0.10.1-0.50.5-2.20.8
Std. dev. time between licks in bursts1.21.45.4-0.3-1.20.5-0.32.30.7-1.11.12.20.31.40.0
Water consumed over 24 hours0.40.43.0-0.10.50.0-0.2-1.1-0.00.3-0.3-0.70.2-1.70.3
Indifference point 0 sec0.10.20.5-0.5-0.30.2-0.20.70.5-0.40.40.40.30.20.4
Indifference point AUC0.00.10.10.2-0.3-0.30.3-0.0-0.20.1-0.10.0-0.30.30.3
Indifference point function ln k0.70.91.91.0-0.8-1.11.1-0.2-1.01.0-1.0-0.7-1.01.0-1.4
Indifference point function log k0.70.91.91.0-0.8-1.11.1-0.2-1.01.0-1.0-0.7-1.01.0-1.4
Delay discounting total patch changes 0 sec0.10.21.1-0.4-0.40.1-0.11.00.5-0.40.40.50.30.30.3
Delay discounting total patch changes 12 sec0.00.00.4-0.1-0.0-0.20.1-0.00.10.0-0.0-0.10.0-0.00.6
Delay discounting total patch changes 18 sec0.50.72.70.5-1.6-0.70.81.1-0.30.2-0.20.3-0.71.4-0.3
Delay discounting total patch changes 24 sec0.60.71.9-0.90.20.8-0.81.41.0-0.90.91.00.9-0.10.7
Delay discounting total patch changes 6 sec0.30.50.8-0.90.30.7-0.80.10.9-0.60.60.40.8-0.50.9
Delay discounting time to switch 0 sec0.40.60.80.7-0.2-0.70.7-0.8-0.80.9-0.9-0.8-0.80.3-0.9
Delay discounting water rate 0 sec2.13.36.7-1.70.41.7-1.62.61.9-2.12.12.11.9-0.71.8
Delay discounting water rate 12 sec0.40.53.2-0.1-1.00.2-0.11.80.3-0.60.61.00.30.40.0
Delay discounting water rate 18 sec0.81.13.1-0.7-0.40.9-0.71.80.9-1.21.21.61.00.30.2
Delay discounting water rate 24 sec2.12.912.6-1.2-0.71.3-1.03.61.5-1.91.92.41.30.10.9
Delay discounting water rate 6 sec0.10.20.9-0.1-0.60.3-0.30.90.2-0.40.40.70.50.10.0
Locomotor activity0.50.91.51.0-1.2-1.01.0-0.6-1.01.0-1.0-0.9-0.80.6-0.9
Locomotor testing distance0.71.22.51.1-1.6-1.01.10.0-1.11.1-1.1-0.6-0.91.1-1.4
Locomotor testing rearing0.30.51.60.8-1.2-0.60.70.4-0.70.6-0.6-0.2-0.50.9-0.9
Light reinforcement 11.12.14.8-1.20.31.5-1.31.91.5-1.91.92.21.10.20.9
Light reinforcement 22.43.24.8-1.80.62.1-2.11.42.0-2.22.22.12.0-0.61.3
Reaction time number correct1.82.68.90.5-3.0-0.10.42.9-0.1-0.80.82.1-0.42.5-0.9
Reaction time mean minus median0.20.21.20.00.30.0-0.1-1.1-0.10.4-0.4-0.8-0.0-0.3-0.1
Reaction time mean minus median AUC0.10.10.6-0.10.00.5-0.6-0.80.10.0-0.0-0.20.2-0.10.1
Reaction time num false alarms0.20.30.50.50.3-0.70.70.0-0.50.5-0.5-0.4-0.60.5-0.7
Reaction time num false alarms AUC0.50.71.51.0-0.1-1.01.0-0.2-0.90.9-0.9-0.6-0.90.9-1.2
Reaction time trials correct on left1.82.68.90.5-3.0-0.10.42.9-0.1-0.80.82.1-0.42.5-0.9
Reaction time trials on left1.92.79.20.5-3.0-0.00.33.0-0.0-0.80.82.2-0.42.6-1.0
Reaction time mean0.30.30.6-0.60.10.7-0.70.80.6-0.70.70.60.40.00.5
Reaction time mean AUC0.30.41.0-0.5-0.40.7-0.61.00.6-0.70.70.90.30.40.2
Median of all reaction times0.30.41.3-0.5-0.10.7-0.61.10.6-0.80.80.90.30.20.5
Reaction time omissions0.30.41.0-0.4-0.40.7-0.61.00.5-0.50.50.80.60.7-0.2
Reaction time false alarm rate0.81.12.60.61.4-0.90.7-1.6-0.81.2-1.2-1.6-0.6-0.5-0.6
Reaction time premature initiation rate1.31.83.11.5-0.7-1.71.8-0.7-1.51.6-1.6-1.3-1.30.7-1.2
Reaction time premature initiations1.52.14.51.6-2.1-1.51.81.0-1.40.9-0.90.0-1.42.0-1.5
Std. dev. reaction times0.20.30.50.7-0.7-0.50.5-0.2-0.60.6-0.6-0.5-0.70.7-0.7
Reaction time trials completed1.92.79.20.5-3.0-0.00.33.0-0.0-0.80.82.2-0.42.6-1.0
Reaction time trials AUC1.92.79.00.5-3.00.00.33.00.0-0.90.92.2-0.42.5-0.9
Social response proportion0.50.50.90.8-1.0-0.70.70.2-0.80.7-0.7-0.3-0.60.9-0.7
Social responses0.10.10.50.2-0.2-0.20.20.2-0.10.1-0.10.2-0.10.7-0.6
Social time0.10.10.40.3-0.1-0.30.40.1-0.20.1-0.10.2-0.50.6-0.6
Conditioned locomotion4.04.87.4-2.20.92.4-2.32.42.3-2.62.62.72.0-0.72.1
Cocaine response after cond. corrected0.10.20.40.10.5-0.50.50.1-0.20.4-0.4-0.6-0.4-0.40.0
Cocaine response after cond. not corrected0.50.61.00.70.1-1.01.0-0.5-0.80.9-0.9-1.0-0.9-0.0-0.6
Cocaine response before conditioning0.80.91.81.1-1.2-0.80.8-0.9-1.00.9-0.9-0.4-0.81.2-1.3
Saline control response3.04.05.1-2.20.92.3-2.31.32.3-2.32.32.02.2-1.52.0
Condit. Reinf. active minus inactive responses0.70.91.5-0.80.31.1-1.10.60.8-1.01.01.01.2-0.81.2
Condit. Reinf. active-inactive response ratio2.32.43.8-1.61.21.8-1.90.41.5-1.51.51.01.7-1.92.0
Condit. Reinf. active responses0.20.20.9-0.1-0.10.3-0.30.90.2-0.50.50.60.4-0.20.7
Condit. Reinf. inactive responses0.60.81.51.0-0.9-1.11.20.5-0.90.7-0.7-0.4-1.01.0-0.8
Condit. Reinf. lever presses0.30.42.8-0.2-0.20.2-0.01.70.3-0.50.50.90.10.30.4
Condit. Reinf. lever reinforcers received0.20.32.4-0.1-0.30.2-0.01.50.2-0.50.50.80.3-0.00.6
Pavlov. Cond. lever latency0.70.94.90.50.3-0.60.4-2.2-0.71.0-1.0-1.4-0.5-0.5-0.6
Pavlov. Cond. magazine entry latency1.92.24.11.6-1.6-1.71.80.7-1.51.2-1.2-0.3-1.62.0-1.6
Pavlov. Cond. change in total contacts0.50.72.80.6-1.0-0.80.91.7-0.50.2-0.20.4-0.81.2-0.5
Pavlov. Cond. index score0.50.63.00.6-0.7-0.60.81.7-0.40.2-0.20.5-0.61.1-0.5
Pavlov. Cond. latency score0.50.63.10.5-0.8-0.50.71.8-0.30.1-0.10.6-0.51.2-0.4
Pavlov. Cond. lever contacts0.91.35.6-0.7-0.40.8-0.62.40.9-1.31.31.70.60.50.8
Pavlov. Cond. magazine entry number1.41.74.1-1.41.41.4-1.6-1.11.2-1.01.00.11.4-2.01.4
Pavlov. Cond. intertrial magazine entries1.51.92.7-1.40.61.6-1.70.91.4-1.61.61.41.5-1.11.5
Pavlov. Cond. lever-magazine prob. diff.0.60.82.90.7-0.8-0.81.01.7-0.50.3-0.30.3-0.81.3-0.6
Pavlov. Cond. response bias0.40.53.50.1-0.8-0.00.31.90.1-0.40.40.9-0.20.90.1
Conditioned reinforcement - actives0.30.31.5-0.1-0.60.6-0.50.30.2-0.20.20.70.31.2-0.3
Conditioned reinforcement - inactives1.51.73.0-1.31.11.7-1.71.11.3-1.11.10.91.7-1.01.2
Conditioned locomotion0.30.31.1-0.4-0.21.0-1.00.20.4-0.20.20.50.80.5-0.1
Intermittent access intake day 1-15 change0.80.82.0-0.91.40.9-0.80.60.9-0.80.80.60.8-0.81.2
Intermittent access intake escalation0.70.71.2-0.91.10.9-0.80.70.9-0.80.80.70.8-0.71.0
Intermittent access intake escalation 22.32.33.7-1.71.71.6-1.60.71.6-1.21.20.61.9-1.71.9
Intermitt. access day 1 inactive lever presses1.31.44.2-1.20.91.1-1.21.11.2-1.01.00.61.3-2.01.3
Intermitt. access day 15 inactive lever presses1.41.52.4-1.00.91.6-1.41.41.2-1.31.31.41.5-0.30.7
Intermitt. access escalation Index1.00.92.3-0.7-0.01.1-1.11.20.8-1.11.11.50.90.40.4
Intermittent access day 1 total infusions0.30.30.5-0.6-0.20.6-0.50.30.6-0.70.70.70.3-0.10.7
Intermittent access day 15 total infusions0.70.81.2-0.90.51.1-0.90.90.9-1.01.01.00.8-0.30.9
Intermittent access terminal intake (last 3 days)1.31.42.4-1.30.71.5-1.40.81.3-1.21.21.11.3-0.41.3
Intermittent access total infusions0.50.61.0-0.80.21.0-0.90.60.9-0.90.90.90.7-0.20.8
Intermittent access day 1 locomotion0.40.41.0-0.6-0.21.0-0.90.80.6-0.60.60.90.70.10.3
Intermittent access day 15 total locomotion0.40.51.1-0.8-0.11.0-1.0-0.00.8-0.50.50.50.8-0.60.8
Intermittent access total locomotion0.50.61.5-0.80.31.2-1.10.50.8-0.60.60.80.9-0.50.7
Intermittent access standard deviation0.60.62.00.11.4-0.40.5-0.8-0.30.6-0.6-1.3-0.1-1.30.2
Cocaine induced anxiety4.95.711.7-2.73.02.2-2.11.42.4-1.91.90.72.7-3.42.7
Post-drug Anxiety0.80.82.9-0.91.70.5-0.40.50.7-0.40.4-0.21.0-1.71.0
Baseline Anxiety7.47.810.33.2-2.0-2.82.8-2.0-3.12.9-2.9-1.9-3.13.0-3.2
Lifetime Intake0.20.20.5-0.40.10.7-0.60.20.4-0.40.40.50.4-0.10.4
Incentive Sensitization - Responses0.10.10.5-0.40.70.5-0.4-0.10.4-0.30.30.40.1-0.20.6
Incentive Sensitization - Breakpoint0.10.10.5-0.30.70.4-0.4-0.20.3-0.20.20.30.0-0.20.5
Progressive ratio test 1 active lever presses1.21.21.8-1.20.11.3-1.20.91.3-1.31.31.31.1-0.41.0
Progressive ratio test 1 breakpoint1.51.52.2-1.30.51.4-1.31.01.4-1.51.51.41.2-0.61.2
Progressive ratio test 1 inactive lever presses2.72.94.0-1.70.51.9-1.81.91.9-2.02.01.91.7-1.01.5
Progressive ratio test 2 active lever presses0.40.40.9-0.70.40.9-0.90.10.7-0.50.50.60.6-0.30.7
Progressive ratio test 2 breakpoint0.50.51.1-0.70.31.0-1.00.30.7-0.70.70.90.7-0.10.7
Progressive ratio test 2 inactive lever presses0.40.51.0-0.80.41.0-0.90.30.7-0.60.60.40.9-0.60.8
Total sessions with >9 infusions0.20.30.70.5-0.3-0.00.0-0.8-0.50.5-0.5-0.2-0.40.8-0.6
Short access day 1 total inactive lever presses0.40.52.50.2-1.60.6-0.50.3-0.10.0-0.00.70.21.1-0.7
Short access day 10 total inactive lever presses3.33.65.3-2.01.71.9-1.91.32.0-1.91.91.51.9-2.32.2
Short access day 1 total infusions1.41.52.31.3-1.0-1.01.1-1.2-1.31.5-1.5-1.2-1.20.8-1.4
Short access day 10 total infusions0.50.60.9-0.90.60.9-0.80.30.9-0.70.70.50.8-0.80.9
Short access total infusions0.00.00.1-0.00.30.2-0.1-0.20.00.1-0.10.0-0.1-0.00.1
Short access day 1 locomotion0.40.41.80.5-0.3-0.30.2-1.3-0.60.7-0.7-0.9-0.40.3-0.5
Short access day 10 total locomotion0.20.30.80.00.30.1-0.2-0.9-0.20.6-0.6-0.90.1-0.90.2
Short access total locomotion0.50.52.10.50.2-0.20.1-1.4-0.60.9-0.9-1.0-0.5-0.2-0.3
Compulsive drug intake0.60.61.6-0.60.80.5-0.41.30.7-0.90.90.80.6-0.50.5
One hour access (0.3 mA shock)1.31.52.3-1.30.81.4-1.31.21.4-1.51.51.51.1-0.31.2
One hour access (shock baseline)0.20.30.8-0.4-0.10.9-0.90.00.4-0.50.50.80.40.50.2
Number of responses in last shaping day1.21.23.0-1.00.71.7-1.60.91.1-1.01.01.11.4-0.30.7
Context. condit. distance diff. score0.91.14.7-0.3-1.20.5-0.32.20.6-1.01.01.80.50.70.2
Locomotion velocity, session 12.52.75.81.50.2-1.61.5-2.2-1.82.0-2.0-2.4-1.4-0.1-0.9
Locomotion distance, session 12.73.54.62.1-2.0-2.12.1-0.4-2.01.8-1.8-0.9-2.12.1-2.1
Locomotion velocity, session 24.65.47.42.5-1.4-2.42.3-2.5-2.62.7-2.7-2.4-2.21.2-2.2
Locomotion distance, session 20.50.81.81.0-1.3-0.90.90.2-0.80.6-0.60.1-0.81.3-0.9
Locomotion velocity, session 31.72.03.21.3-0.9-1.51.4-1.5-1.51.7-1.7-1.8-1.40.4-1.2
Locomotion distance, session 33.13.44.51.9-1.6-2.12.1-1.2-2.02.1-2.1-1.7-1.91.2-1.9
Stereotopy head waving bouts, day 30.60.71.70.7-0.5-0.70.7-1.3-0.81.0-1.0-1.2-0.70.0-0.6
Stereotopy head waving duration, day 30.30.40.80.6-0.9-0.50.5-0.8-0.60.7-0.7-0.7-0.50.3-0.5
Locomotion velocity, session 70.60.71.20.9-0.5-1.01.0-0.2-0.80.9-0.9-0.5-0.80.9-1.1
Locomotion distance, session 73.03.85.52.2-2.0-2.22.30.3-2.11.7-1.7-0.7-2.22.3-2.2
Stereotopy head waving bouts, day 70.20.20.4-0.5-0.20.4-0.30.60.5-0.50.50.50.6-0.20.3
Stereotopy head waving duration, day 70.40.51.2-0.8-0.10.9-0.90.00.8-0.70.70.51.1-0.50.6
Locomotion velocity, session 80.60.81.61.0-1.0-0.91.00.6-0.90.6-0.60.3-0.81.3-1.1
Locomotion distance, session 81.11.76.50.3-2.2-0.10.32.50.1-0.60.62.0-0.11.8-0.6
Degree of sensitization distance0.60.61.9-0.40.40.6-0.51.40.6-0.90.91.20.40.20.5
Degree of sensitization stereotypy0.50.51.2-0.70.00.6-0.61.10.8-0.80.80.80.9-0.30.6
Condit. Reinf. active minus inactive responses2.42.63.2-1.71.51.6-1.61.61.7-1.81.81.71.8-1.01.5
Condit. Reinf. active-inactive response ratio1.11.21.7-1.11.01.0-0.91.31.2-1.21.21.11.1-0.51.0
Condit. Reinf. active responses4.15.06.3-2.31.82.4-2.32.02.4-2.52.52.42.5-1.42.2
Condit. Reinf. inactive responses1.11.21.6-1.10.91.2-1.11.01.1-1.21.21.21.3-0.91.2
Incentive salience index mean1.92.33.2-1.61.31.6-1.61.31.7-1.71.71.71.8-0.71.3
Condit. Reinf. lever presses0.10.10.4-0.0-0.20.2-0.10.40.2-0.20.20.70.30.6-0.3
Time in familiar zone, hab. session 10.20.20.80.20.9-0.30.3-0.0-0.30.3-0.3-0.5-0.3-0.60.1
Time in novel zone, hab. session 10.10.10.7-0.0-0.90.2-0.20.10.1-0.20.20.30.10.4-0.1
Total zone transitions, hab. session 10.40.51.00.8-0.6-0.91.00.5-0.70.6-0.6-0.2-0.80.7-0.8
Total locomotion distance, hab. session 10.30.42.8-0.20.0-0.00.21.70.4-0.50.50.90.20.6-0.3
Locomotion velocity, hab. session 10.30.42.8-0.30.00.10.11.70.5-0.60.61.00.20.6-0.3
Time in familiar zone, hab. session 20.30.30.70.5-0.1-0.80.90.7-0.50.4-0.4-0.1-0.60.6-0.6
Time in novel zone, hab. session 20.10.10.60.3-0.60.0-0.1-0.8-0.30.2-0.2-0.2-0.20.1-0.1
Total zone transitions, hab. session 20.70.92.30.9-1.4-0.80.91.2-0.60.3-0.30.8-0.71.5-0.9
Total locomotion distance, hab. session 20.81.03.8-0.2-1.00.4-0.22.00.5-0.90.91.90.41.1-0.2
Locomotion velocity, hab. session 20.91.24.1-0.5-0.70.7-0.52.00.8-1.21.22.00.70.90.1
Novel to familiar place preference ratio2.83.04.2-2.02.01.7-1.70.71.8-1.61.60.71.9-2.12.0
Novelty place preference2.72.84.3-1.92.11.7-1.70.61.8-1.51.50.61.9-2.12.0
Time in novel zone, NPP test2.12.33.3-1.71.81.5-1.50.71.6-1.41.40.61.7-1.81.8
Total zone transitions, NPP test1.01.54.41.1-2.0-0.91.11.2-0.80.4-0.40.9-1.02.1-1.4
Total locomotion distance, NPP test0.81.24.20.3-1.5-0.10.32.10.1-0.50.51.8-0.11.7-0.8
Locomotion velocity, NPP test0.70.94.0-0.0-1.10.20.02.00.4-0.70.71.70.11.3-0.4
Pavlov. Cond. lever latency1.51.93.61.4-1.2-1.51.71.6-1.10.8-0.80.3-1.71.9-1.4
Pavlov. Cond. magazine entry latency2.73.56.6-2.02.61.8-1.90.01.8-1.51.50.42.1-2.52.3
Pavlov. Cond. change in total contacts0.60.62.1-0.81.20.5-0.5-0.60.6-0.20.2-0.60.7-1.50.8
Pavlov. Cond. index score3.44.36.6-2.32.12.4-2.5-0.12.2-1.91.90.92.6-2.32.3
Pavlov. Cond. latency score2.83.65.7-2.11.92.2-2.3-0.61.9-1.61.60.52.4-2.32.1
Pavlov. Cond. lever contacts1.01.22.2-1.20.91.3-1.4-0.91.1-0.80.80.21.5-1.21.0
Pavlov. Cond. magazine entry number2.53.27.71.9-2.7-1.61.70.4-1.61.2-1.20.1-1.92.8-2.3
Pavlov. Cond. intertrial magazine entries0.30.41.6-0.30.10.4-0.31.30.4-0.70.71.20.10.60.1
Pavlov. Cond. lever-magazine prob. diff.3.64.56.4-2.42.22.4-2.40.12.2-2.02.00.92.5-2.32.4
Pavlov. Cond. response bias2.43.05.8-1.92.31.7-1.8-0.51.6-1.31.30.11.9-2.42.1
Bone: apparent density0.20.30.8-0.50.00.4-0.40.70.6-0.70.70.90.30.30.1
Bone surface0.30.50.8-0.80.40.9-0.9-0.20.9-0.80.80.70.8-0.20.5
Bone volume0.30.40.7-0.80.30.7-0.70.40.8-0.80.80.80.7-0.00.4
Bone: connectivity density0.10.20.70.2-0.70.0-0.10.1-0.0-0.10.10.7-0.10.9-0.4
Bone: cortical apparent density2.53.34.51.9-1.1-2.12.1-1.2-2.02.1-2.1-1.9-2.11.0-1.6
Bone: cortical area6.610.013.6-3.73.03.5-3.51.63.7-3.43.42.63.5-2.32.8
Bone: cortical porosity1.71.85.8-1.32.41.0-1.1-0.91.0-0.50.5-0.81.3-2.41.4
Bone: cortical porosity1.71.84.9-1.52.21.1-1.2-0.41.2-0.80.8-0.31.4-2.21.4
Bone: cortical thickness5.59.112.6-3.53.53.3-3.40.93.4-3.13.11.93.3-2.82.9
Bone: cortical thickness1.82.23.3-1.71.81.5-1.41.01.7-1.51.51.01.5-1.41.4
Bone: cortical tissue density2.93.85.22.0-1.2-2.32.2-1.3-2.12.2-2.2-2.1-2.31.1-1.7
Bone: elastic displacement1.51.72.6-1.61.61.3-1.30.51.6-1.31.30.81.2-1.11.3
Bone: elastic work7.59.715.0-3.73.93.2-3.20.93.5-3.13.11.53.2-3.33.4
Bone: endosteal estimation0.20.41.50.2-1.2-0.10.21.20.0-0.30.30.8-0.20.9-0.3
Bone: endosteal perimeter0.71.52.1-1.41.21.4-1.40.61.5-1.41.41.11.4-0.70.9
Bone: final force5.69.212.0-3.42.13.3-3.32.23.5-3.43.42.73.4-2.33.0
Bone: final moment6.510.714.1-3.82.63.6-3.52.33.8-3.63.62.73.6-2.63.3
Bone: marrow area0.20.41.50.2-1.2-0.10.21.2-0.0-0.20.20.8-0.20.9-0.3
Bone: maximum diameter1.73.14.6-2.11.32.1-2.10.62.1-2.02.01.62.1-1.01.2
Bone: maximum force5.59.512.1-3.42.13.4-3.32.33.5-3.53.52.93.4-2.33.1
Bone: maximum moment6.311.014.0-3.72.53.6-3.52.43.7-3.73.72.93.6-2.63.4
Bone: minimum diameter3.66.79.6-3.12.52.8-2.81.63.1-2.82.82.23.0-1.82.1
Bone: periosteal estimation2.04.25.8-2.31.12.3-2.21.72.4-2.42.42.22.2-1.01.7
Bone: periosteal perimeter3.66.08.3-2.92.92.8-2.80.22.7-2.42.41.42.8-2.42.3
Bone: post-yield work0.10.20.50.3-0.6-0.10.20.6-0.2-0.00.00.5-0.30.7-0.3
Bone: stiffness0.71.11.5-1.10.11.2-1.20.91.2-1.21.21.21.2-0.71.0
Bone: tissue strength1.41.42.8-1.20.31.2-1.21.31.3-1.41.41.71.1-0.00.7
Bone: trabecular number0.00.00.0-0.10.00.2-0.2-0.20.1-0.10.10.20.10.1-0.0
Bone: trabecular spacing0.91.26.3-0.0-1.2-0.00.22.50.4-0.70.71.8-0.01.5-0.4
Bone: trabecular thickness0.91.13.6-1.01.90.8-0.9-0.90.7-0.40.4-0.60.8-1.71.2
Bone: trabecular tissue density0.91.21.51.2-0.9-1.21.2-0.8-1.21.2-1.2-1.0-1.20.8-1.0
Breakpoint value in progressive ratio session0.50.62.4-0.90.50.3-0.30.80.7-0.40.4-0.10.9-1.50.9
Distance traveled before self-admin1.81.95.1-1.52.31.1-1.00.81.4-1.11.10.31.6-1.71.6
Distance traveled after self-admin0.60.61.9-0.7-0.50.4-0.31.40.8-1.01.01.10.8-0.10.6
Delta time in closed arm before/after self-admin0.30.20.80.2-0.40.7-0.8-0.7-0.20.2-0.20.20.20.9-0.4
Delta time in open arm before/after self-admin0.20.21.4-0.1-0.4-0.20.31.20.2-0.30.30.30.0-0.0-0.1
Diff in mean of infusions in LGA sessions0.20.20.70.3-0.8-0.40.4-0.3-0.40.5-0.5-0.6-0.00.3-0.6
Extinction: sum of active levers before priming1.11.12.11.0-0.3-1.21.1-0.7-1.11.2-1.2-1.5-1.0-0.4-1.1
Active lever presses in extinction session 60.40.41.90.10.1-0.30.30.1-0.20.7-0.7-1.10.3-1.4-0.2
Delta distance traveled before/after self-admin1.01.05.10.9-2.2-0.70.80.4-0.70.3-0.30.3-0.91.6-1.1
Delta ambulatory time before/after self-admin1.82.06.81.4-2.6-1.21.2-0.1-1.31.0-1.0-0.2-1.42.1-1.6
Time in closed arm before self-admin0.40.51.10.10.8-1.00.8-0.7-0.20.3-0.3-0.9-0.7-1.00.2
Time in closed arm after self-admin1.11.13.80.61.0-0.70.4-2.0-0.81.1-1.1-1.7-0.8-1.0-0.1
Time in open arm before self-admin0.40.51.90.3-1.30.6-0.6-0.6-0.20.3-0.30.20.31.4-0.7
Time in open arm after self-admin0.30.31.70.4-1.3-0.20.30.4-0.20.0-0.00.3-0.11.0-0.7
Sum of active levers in priming session hrs 5-60.70.72.6-0.90.30.00.01.60.8-0.50.50.01.0-1.31.2
Time to tail flick, vehicle, before self-admin0.10.10.8-0.2-0.90.3-0.30.10.3-0.30.30.40.1-0.40.2
Time to tail flick, vehicle, after self-admin2.12.23.31.6-0.6-1.41.4-1.7-1.61.6-1.6-1.2-1.51.4-1.8
Time to tail flick, test, before self-admin0.10.10.9-0.20.10.2-0.2-0.40.10.1-0.1-0.20.2-0.90.5
Time to tail flick, test, after self-admin0.20.30.60.5-0.60.0-0.1-0.5-0.50.8-0.8-0.50.10.2-0.6
Delta time to tail flick, vehicle, before/after SA0.40.42.00.7-0.0-0.40.4-0.1-0.60.6-0.6-0.0-0.41.4-1.0
Delta time to tail flick, test, before/after SA0.50.40.80.5-0.6-0.50.4-0.6-0.60.8-0.8-0.9-0.50.7-0.6
Ambulatory time before self-admin3.03.14.5-2.02.01.5-1.51.31.9-1.71.70.92.1-2.12.0
Ambulatory time after self-admin0.40.41.2-0.6-0.20.4-0.41.10.7-0.80.80.80.8-0.20.5
Total heroin consumption0.30.41.8-0.50.90.2-0.10.20.30.0-0.0-0.70.8-1.30.3
Area under the delay curve1.81.92.81.6-0.9-1.71.6-0.8-1.61.5-1.5-1.3-1.60.7-1.4
Delay disc. indifference point, 0s delay0.00.00.10.2-0.3-0.10.10.1-0.20.2-0.2-0.1-0.10.1-0.2
Delay disc. indifference point, 16s delay2.22.24.01.7-2.0-1.41.60.3-1.61.2-1.2-0.4-1.52.0-1.9
Delay disc. indifference point, 2s delay0.40.40.80.6-0.3-0.70.7-0.4-0.70.9-0.9-0.7-0.4-0.3-0.5
Delay disc. indifference point, 24s delay4.94.76.62.3-0.6-2.42.4-1.8-2.42.6-2.6-2.5-2.30.9-2.2
Delay disc. indifference point, 4s delay0.60.60.90.7-0.7-1.00.8-0.9-0.80.8-0.8-0.8-0.90.3-0.6
Delay disc. indifference point, 8s delay1.01.01.91.00.2-1.21.1-1.1-1.11.2-1.2-1.4-1.1-0.1-0.7
Delay discount exponential model param2.62.73.9-1.81.02.0-1.91.21.9-1.91.91.71.9-0.71.5
Delay discount hyperbolic model param2.42.63.8-1.71.01.9-1.91.11.8-1.81.81.61.8-0.61.5
Fecal boli incidents, locomotor time 10.50.50.80.8-0.3-0.80.9-0.5-0.80.9-0.9-0.4-0.70.6-0.9
Change in fecal boli incidents, locomotor task2.22.14.51.1-1.1-1.71.5-1.8-1.41.5-1.5-2.1-1.40.5-0.7
Time >=10cm from walls, locomotor time 10.60.61.7-0.3-0.60.5-0.40.50.5-1.21.21.3-0.00.70.4
Bouts of movement, locomotor time 11.71.93.01.5-0.6-1.71.6-1.0-1.51.5-1.5-1.4-1.70.8-1.4
Total resting periods, locomotor time 12.12.33.51.5-0.4-1.91.6-1.5-1.61.7-1.7-1.7-1.90.5-1.4
Rest time, locomotor task time 10.30.30.70.20.6-0.40.2-0.8-0.30.7-0.7-0.8-0.4-0.6-0.1
Distance moved, locomotor task time 10.50.61.2-0.70.10.8-0.80.80.8-1.11.11.00.60.40.3
Vertical activity count, locomotor time 11.31.32.7-0.90.21.3-1.21.51.1-1.51.51.61.10.20.3
Time >=10cm from walls, locomotor time 20.10.10.70.0-0.30.4-0.5-0.9-0.0-0.10.10.2-0.10.50.1
Bouts of movement, locomotor time 21.31.42.41.4-0.7-1.41.4-0.7-1.41.3-1.3-0.9-1.50.5-1.1
Total resting periods, locomotor time 20.90.91.61.2-0.8-1.11.0-0.5-1.21.0-1.0-0.5-1.30.7-1.0
Rest time, locomotor task time 20.10.10.60.20.1-0.30.2-0.8-0.30.2-0.2-0.3-0.5-0.2-0.3
Distance moved, locomotor task time 20.10.10.3-0.1-0.40.3-0.40.20.1-0.10.10.20.20.6-0.1
Vertical activity count, locomotor time 20.30.30.8-0.0-0.60.6-0.50.80.2-0.40.40.90.30.8-0.2
Weight adjusted by age3.23.65.6-2.01.72.0-2.12.02.0-2.02.01.42.4-1.01.8
Seeking ratio, delayed vs. immediate footshock1.41.62.2-1.41.01.4-1.30.81.5-1.51.51.41.4-0.21.2
Locomotion in novel chamber0.20.30.60.7-0.7-0.40.40.4-0.60.3-0.3-0.1-0.50.7-0.8
Locomotion in novel chamber post-restriction2.12.53.7-1.71.61.5-1.50.51.7-1.91.91.41.2-1.31.9
Progressive ratio0.40.40.90.7-0.1-0.60.8-0.4-0.80.9-0.9-0.7-0.50.3-0.7
Food seeking constrained by brief footshock0.30.41.90.30.5-0.60.6-0.6-0.40.5-0.5-0.9-0.3-1.4-0.1
Seeking ratio, punishment vs. effort0.10.20.4-0.40.10.2-0.30.50.4-0.60.60.50.2-0.60.4
Run reversals in cocaine runway, females1.21.23.61.0-1.9-1.41.40.6-0.90.4-0.4-0.1-1.31.2-1.0
Run reversals in cocaine runway, males1.51.52.6-1.41.61.3-1.3-0.11.2-0.80.80.21.4-1.61.6
Latency to leave start box in cocaine runway0.30.30.80.6-0.5-0.70.7-0.3-0.50.5-0.5-0.1-0.80.9-0.6
Latency to leave start box in cocaine runway, F0.60.73.00.6-1.5-0.50.50.1-0.40.4-0.40.5-0.71.7-1.0
Latency to leave start box in cocaine runway, M0.20.21.3-0.21.1-0.1-0.0-0.30.1-0.10.1-0.1-0.2-0.70.6
Cd content in liver1.82.03.61.7-1.0-1.81.9-0.0-1.61.5-1.5-1.0-1.70.5-1.4
Co content in liver0.10.20.60.2-0.8-0.40.50.4-0.20.3-0.3-0.1-0.4-0.1-0.6
Cu content in liver0.81.05.0-0.91.50.7-0.8-0.80.8-0.30.3-0.40.9-2.20.7
Fe content in liver1.01.11.61.1-1.0-1.21.2-0.3-1.11.1-1.1-0.7-1.21.1-1.3
K content in liver2.22.24.2-1.50.21.7-1.71.21.7-1.71.72.11.6-0.41.0
Mg content in liver0.60.62.3-0.1-1.10.5-0.50.90.4-0.60.61.50.21.2-0.2
Mn content in liver0.30.40.8-0.60.40.7-0.9-0.30.6-0.60.60.40.9-0.60.6
Na content in liver0.00.00.1-0.20.10.3-0.3-0.40.2-0.10.10.00.3-0.2-0.1
Rb content in liver0.81.02.4-0.8-0.10.9-0.81.50.9-1.21.21.50.90.10.8
Se content in liver0.30.40.6-0.60.50.6-0.60.60.7-0.70.70.70.70.30.6
Sr content in liver0.70.62.9-0.01.7-0.20.2-1.3-0.20.5-0.5-1.4-0.1-0.10.1
Zn content in liver0.20.22.2-0.00.60.3-0.4-1.5-0.00.2-0.2-0.20.1-0.3-0.1