Hub : Genes

Pycr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA isoform ratio ENSRNOT00000054949 0.1 0.07 4.4e-04 0.07 0.05 0.04 0.04 1.7e-04 1.2e-03 2.6e-03 3.3e-03
2 BLA isoform ratio ENSRNOT00000110897 0.07 0.06 5.2e-03 0.04 0.02 0.02 0.01 5.0e-03 1.9e-02 3.6e-02 5.4e-02
3 BLA mRNA stability ENSRNOG00000036682 0.14 0.08 9.8e-06 0.11 0.1 0.1 0.11 1.4e-06 6.7e-06 6.6e-06 2.4e-06
4 Brain isoform ratio ENSRNOT00000054949 0.11 0.06 1.5e-07 0.04 0.07 0.06 0.06 3.4e-04 6.1e-07 1.5e-06 3.8e-06
5 Brain isoform ratio ENSRNOT00000110897 0.08 0.05 8.6e-05 0.02 0.04 0.04 0.04 3.6e-03 5.8e-05 6.7e-05 1.4e-04
6 Brain mRNA stability ENSRNOG00000036682 0.06 0.04 2.1e-04 0.02 0.04 0.04 0.03 2.8e-03 1.9e-04 2.6e-04 6.2e-04
7 IL alternative TSS ENSRNOT00000110897 0.16 0.12 9.4e-03 0.06 0.01 0.04 0.03 1.7e-02 1.6e-01 3.4e-02 7.3e-02
8 NAcc isoform ratio ENSRNOT00000054949 0.06 0.04 4.1e-03 0.04 0.02 0.02 0.03 3.4e-04 2.3e-02 7.9e-03 2.1e-03
9 PL isoform ratio ENSRNOT00000054949 0.11 0.06 4.8e-06 0.06 0.07 0.05 0.06 1.1e-05 5.7e-06 1.5e-04 1.1e-05
10 PL isoform ratio ENSRNOT00000110897 0.12 0.07 1.5e-06 0.07 0.07 0.06 0.07 2.6e-06 3.5e-06 1.8e-05 6.1e-06
11 PL intron excision ratio chr10:105920645:105920850 0.04 0.03 8.7e-03 0.02 0.02 0.02 0.02 5.8e-03 1.2e-02 1.1e-02 6.5e-03
12 PL intron excision ratio chr10:105920645:105921642 0.03 0.03 9.8e-03 0.01 0.02 0.01 0.01 4.7e-02 5.7e-03 2.3e-02 3.3e-02
13 PL mRNA stability ENSRNOG00000036682 0.12 0.08 4.8e-06 0.07 0.08 0.07 0.07 2.6e-06 1.6e-06 3.2e-06 6.4e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.72.13.92.0-2.01.61.1-1.11.3-0.32.01.6-1.6-0.41.01.6
BMI without tail6.012.518.74.3-4.34.23.1-2.93.3-0.54.34.3-4.2-0.72.44.2
Body weight1.77.114.93.4-3.42.80.8-0.61.1-2.33.42.7-2.8-2.43.92.5
Epididymis fat weight1.12.54.92.2-2.21.91.1-1.01.2-0.32.21.7-1.9-0.51.21.7
Glucose7.110.916.2-3.73.7-3.9-3.43.2-3.5-1.3-3.7-4.03.9-1.2-0.6-4.0
Heart weight0.10.20.70.5-0.50.3-0.00.10.0-0.80.50.3-0.3-0.60.90.2
Left kidney weight0.20.40.8-0.80.8-0.4-0.80.9-0.8-0.5-0.8-0.50.4-0.60.5-0.5
Right kidney weight0.00.10.2-0.50.50.1-0.20.2-0.20.1-0.5-0.1-0.1-0.0-0.1-0.1
Tail length3.29.514.33.6-3.63.72.0-1.72.3-1.63.63.8-3.7-1.73.53.6
Length with tail0.72.710.21.7-1.71.2-0.40.6-0.2-2.31.71.2-1.2-2.33.21.0
Length without tail2.14.77.2-1.91.9-2.5-2.72.7-2.7-1.3-1.9-2.52.5-1.10.4-2.5
Liver weight, left1.01.52.3-1.11.1-1.4-1.51.5-1.5-1.0-1.1-1.51.4-0.60.3-1.5
Liver weight, right0.50.93.00.9-0.90.8-0.10.3-0.0-1.10.90.8-0.8-1.41.70.7
Parametrial fat weight0.71.43.31.6-1.61.00.1-0.00.3-1.31.61.0-1.0-1.01.80.9
Retroperitoneal fat weight2.27.413.93.7-3.72.90.9-0.71.2-2.23.72.6-2.9-2.13.72.5
Intraocular pressure0.40.61.00.8-0.80.90.6-0.60.7-0.30.81.0-0.9-0.30.70.9
Extensor digitorum longus weight1.03.95.22.3-2.32.12.2-2.22.21.22.32.1-2.11.2-0.42.1
Soleus weight0.61.63.21.3-1.31.60.6-0.50.7-1.01.31.5-1.6-1.01.81.4
Tibialis anterior weight0.30.91.21.1-1.11.11.1-1.11.10.61.11.1-1.10.4-0.21.1
Tibia length2.77.633.30.9-0.90.8-1.92.2-1.5-4.90.90.8-0.8-5.25.80.5
Number of licking bursts0.60.70.90.9-0.91.00.8-0.80.90.50.90.9-1.00.5-0.00.9
Food consumed during 24 hour testing period0.10.20.40.5-0.50.50.2-0.20.3-0.30.50.5-0.5-0.20.60.5
Times rat made contact with spout1.31.53.2-0.80.8-0.9-1.51.5-1.4-1.8-0.7-0.80.9-1.51.6-0.9
Mean time between licks in bursts0.50.72.7-0.60.6-0.50.3-0.30.21.4-0.6-0.40.51.6-1.6-0.4
Mean num. licks in bursts1.11.31.9-0.90.9-1.1-1.31.3-1.3-1.4-1.0-1.01.1-1.20.9-1.1
Std. dev. time between licks in bursts5.06.07.72.8-2.82.72.7-2.72.81.42.82.7-2.71.4-0.32.7
Water consumed over 24 hours0.91.01.4-1.21.2-1.1-1.21.2-1.1-0.5-1.2-1.11.1-0.50.2-1.1
Indifference point 0 sec0.00.10.20.5-0.50.1-0.00.00.0-0.20.50.1-0.10.10.30.1
Indifference point AUC0.10.10.20.2-0.20.50.3-0.30.20.00.20.2-0.50.1-0.10.2
Indifference point function ln k0.20.31.3-0.20.2-0.50.2-0.20.11.1-0.2-0.30.50.9-1.2-0.2
Indifference point function log k0.20.31.3-0.20.2-0.50.2-0.20.11.1-0.2-0.30.50.9-1.2-0.2
Delay discounting total patch changes 0 sec0.10.10.40.7-0.70.20.1-0.10.2-0.10.70.3-0.20.10.30.3
Delay discounting total patch changes 12 sec0.10.10.2-0.10.1-0.2-0.40.4-0.4-0.4-0.1-0.30.2-0.20.3-0.3
Delay discounting total patch changes 18 sec0.70.91.91.4-1.40.71.0-1.00.90.71.40.7-0.70.9-0.50.7
Delay discounting total patch changes 24 sec0.50.61.81.4-1.40.40.3-0.30.4-0.41.40.7-0.4-0.60.80.6
Delay discounting total patch changes 6 sec0.10.20.7-0.20.2-0.0-0.50.5-0.4-0.8-0.2-0.10.0-0.60.9-0.1
Delay discounting time to switch 0 sec0.30.40.7-0.80.8-0.8-0.30.3-0.30.6-0.8-0.60.80.5-0.8-0.6
Delay discounting water rate 0 sec1.52.43.92.0-2.01.91.0-0.91.1-0.92.01.7-1.9-1.11.61.6
Delay discounting water rate 12 sec1.01.52.31.5-1.51.41.3-1.31.30.31.51.3-1.40.40.11.3
Delay discounting water rate 18 sec1.82.43.71.9-1.91.81.5-1.51.60.61.91.7-1.80.40.31.7
Delay discounting water rate 24 sec3.65.08.83.0-3.02.52.0-2.02.20.13.02.4-2.50.40.92.4
Delay discounting water rate 6 sec0.50.81.41.2-1.21.00.9-0.90.90.41.20.9-1.0-0.0-0.00.9
Locomotor activity0.30.40.9-0.50.5-0.9-0.20.2-0.30.7-0.5-0.70.90.9-1.0-0.6
Locomotor testing distance0.30.52.10.1-0.1-0.50.4-0.50.41.50.1-0.10.51.4-1.4-0.0
Locomotor testing rearing0.20.31.00.3-0.3-0.00.6-0.60.51.00.30.20.01.0-0.90.3
Light reinforcement 11.83.35.62.0-2.02.41.8-1.71.90.22.02.2-2.40.00.72.2
Light reinforcement 21.41.93.41.5-1.51.81.0-0.91.2-0.51.51.7-1.8-0.41.31.7
Reaction time number correct6.69.413.13.3-3.33.03.6-3.63.62.33.33.2-3.02.4-1.13.3
Reaction time mean minus median0.60.81.2-1.01.0-0.9-1.11.1-1.1-0.6-1.0-1.10.9-0.40.1-1.1
Reaction time mean minus median AUC0.10.10.1-0.30.3-0.1-0.30.4-0.4-0.3-0.3-0.30.1-0.10.1-0.3
Reaction time num false alarms0.20.30.9-1.01.0-0.5-0.10.0-0.10.4-1.0-0.30.50.3-0.5-0.3
Reaction time num false alarms AUC0.30.41.0-0.90.9-0.50.1-0.20.10.9-0.9-0.30.50.8-1.0-0.2
Reaction time trials correct on left6.69.413.13.3-3.33.03.6-3.63.62.33.33.2-3.02.4-1.13.3
Reaction time trials on left6.99.813.63.4-3.43.03.7-3.73.62.43.43.3-3.02.5-1.13.3
Reaction time mean0.20.30.60.8-0.80.80.4-0.30.4-0.30.80.5-0.8-0.00.50.5
Reaction time mean AUC0.60.81.51.1-1.11.20.8-0.80.90.21.10.9-1.20.40.21.0
Median of all reaction times0.50.71.21.1-1.11.10.7-0.70.7-0.11.10.9-1.10.20.40.9
Reaction time omissions0.40.60.80.9-0.90.70.7-0.70.80.50.90.8-0.70.8-0.00.8
Reaction time false alarm rate2.23.26.3-2.52.5-1.9-1.71.6-1.7-0.3-2.5-1.81.9-0.5-0.3-1.8
Reaction time premature initiation rate0.70.91.5-1.21.2-1.2-0.30.2-0.30.7-1.2-0.81.20.8-1.2-0.8
Reaction time premature initiations1.21.83.90.7-0.70.51.7-1.81.61.90.71.0-0.52.0-1.71.1
Std. dev. reaction times0.10.10.5-0.10.1-0.10.1-0.10.00.4-0.1-0.30.10.7-0.6-0.2
Reaction time trials completed6.99.813.63.4-3.43.03.7-3.73.62.43.43.3-3.02.5-1.13.3
Reaction time trials AUC6.99.813.43.4-3.43.03.7-3.73.62.33.43.3-3.02.5-1.13.3
Social response proportion0.20.20.80.1-0.1-0.10.6-0.60.50.80.10.20.10.9-0.80.2
Social responses0.30.40.90.7-0.70.20.5-0.50.50.90.70.4-0.20.9-0.60.4
Social time0.20.20.70.1-0.10.20.5-0.60.60.80.10.4-0.20.8-0.60.4
Conditioned locomotion3.23.96.22.5-2.52.31.4-1.31.5-0.82.52.3-2.3-0.61.82.2
Cocaine response after cond. corrected0.50.50.8-0.80.8-0.9-0.80.8-0.8-0.4-0.8-0.80.9-0.60.1-0.8
Cocaine response after cond. not corrected0.60.61.1-1.01.0-1.0-0.70.6-0.70.1-1.0-0.91.0-0.2-0.5-0.9
Cocaine response before conditioning0.40.41.7-0.20.20.10.6-0.60.51.3-0.20.1-0.11.1-1.30.2
Saline control response1.01.43.81.3-1.31.30.3-0.20.5-1.21.31.3-1.3-1.22.01.2
Condit. Reinf. active minus inactive responses0.40.60.90.8-0.80.90.4-0.30.4-0.70.80.8-0.9-0.71.00.7
Condit. Reinf. active-inactive response ratio0.70.73.10.3-0.30.4-0.40.5-0.4-1.60.30.4-0.4-1.61.80.2
Condit. Reinf. active responses0.30.50.70.8-0.80.80.7-0.60.6-0.20.80.7-0.8-0.30.40.7
Condit. Reinf. inactive responses0.20.20.80.2-0.20.20.6-0.70.50.70.20.1-0.20.7-0.90.2
Condit. Reinf. lever presses0.70.91.51.2-1.21.01.0-1.01.00.21.21.0-1.00.20.11.0
Condit. Reinf. lever reinforcers received0.50.81.21.1-1.11.00.9-0.90.9-0.01.11.0-1.0-0.10.30.9
Pavlov. Cond. lever latency1.52.13.6-1.91.9-1.6-1.41.4-1.5-0.2-1.9-1.61.6-0.3-0.4-1.6
Pavlov. Cond. magazine entry latency1.21.33.70.6-0.60.41.3-1.41.31.90.60.5-0.41.7-1.80.6
Pavlov. Cond. change in total contacts0.81.11.71.2-1.20.81.2-1.31.20.91.20.9-0.80.9-0.70.9
Pavlov. Cond. index score0.81.01.61.1-1.10.81.2-1.31.21.01.10.9-0.80.8-0.70.9
Pavlov. Cond. latency score1.11.32.01.3-1.31.01.4-1.41.41.11.31.1-1.00.9-0.71.1
Pavlov. Cond. lever contacts2.12.95.02.2-2.21.91.7-1.61.70.22.21.9-1.90.50.51.8
Pavlov. Cond. magazine entry number1.11.43.4-0.80.8-0.5-1.41.5-1.4-1.8-0.8-0.70.5-1.51.6-0.8
Pavlov. Cond. intertrial magazine entries0.70.92.21.0-1.01.20.4-0.30.4-1.11.01.0-1.2-0.91.50.9
Pavlov. Cond. lever-magazine prob. diff.0.81.01.71.1-1.10.71.2-1.31.21.11.10.8-0.70.9-0.80.9
Pavlov. Cond. response bias1.21.72.71.7-1.71.31.4-1.41.40.61.71.3-1.30.8-0.21.3
Conditioned reinforcement - actives0.60.61.00.5-0.51.00.9-0.90.90.80.50.9-1.00.8-0.30.9
Conditioned reinforcement - inactives0.50.62.60.6-0.60.5-0.20.3-0.2-1.10.60.4-0.5-1.61.30.3
Conditioned locomotion0.20.20.30.5-0.50.60.3-0.30.30.20.50.5-0.60.20.10.5
Intermittent access intake day 1-15 change0.30.31.20.2-0.20.5-0.30.3-0.2-1.00.20.2-0.5-0.91.10.1
Intermittent access intake escalation0.20.20.80.2-0.20.60.00.00.1-0.70.20.4-0.6-0.60.90.4
Intermittent access intake escalation 21.11.13.9-0.30.3-0.0-1.11.2-1.0-2.0-0.3-0.30.0-1.61.9-0.4
Intermitt. access day 1 inactive lever presses0.60.62.80.5-0.50.1-0.60.6-0.5-1.30.5-0.0-0.1-1.71.3-0.1
Intermitt. access day 15 inactive lever presses1.01.12.01.4-1.41.10.8-0.80.9-0.21.41.2-1.1-0.30.81.2
Intermitt. access escalation Index1.81.62.61.4-1.41.41.4-1.31.40.51.41.6-1.40.40.31.6
Intermittent access day 1 total infusions0.20.30.50.6-0.60.70.3-0.30.4-0.30.60.6-0.7-0.20.60.5
Intermittent access day 15 total infusions0.50.51.10.8-0.81.00.5-0.40.5-0.40.80.8-1.0-0.30.80.8
Intermittent access terminal intake (last 3 days)0.50.51.50.7-0.70.90.1-0.10.2-0.90.70.7-0.9-0.61.20.6
Intermittent access total infusions0.40.40.80.6-0.60.90.4-0.40.5-0.30.60.8-0.9-0.30.70.7
Intermittent access day 1 locomotion0.50.50.90.8-0.80.90.6-0.60.70.10.80.9-0.9-0.00.30.9
Intermittent access day 15 total locomotion0.10.10.6-0.00.00.4-0.20.3-0.2-0.6-0.00.2-0.4-0.50.80.1
Intermittent access total locomotion0.20.20.50.5-0.50.70.2-0.10.2-0.40.50.5-0.7-0.50.70.5
Intermittent access standard deviation2.12.23.0-1.71.7-1.4-1.71.7-1.7-1.1-1.7-1.71.4-0.80.3-1.7
Cocaine induced anxiety3.54.016.90.1-0.1-0.5-2.02.1-1.8-3.40.1-0.80.5-4.13.0-1.0
Post-drug Anxiety1.41.56.5-0.10.1-0.8-1.41.4-1.3-1.7-0.1-1.00.8-2.61.2-1.0
Baseline Anxiety2.62.710.6-1.21.2-0.90.9-1.00.63.0-1.2-0.50.92.7-3.2-0.4
Lifetime Intake0.10.10.40.3-0.30.60.3-0.30.3-0.10.30.5-0.6-0.10.30.4
Incentive Sensitization - Responses0.10.10.30.3-0.30.10.10.00.1-0.30.30.3-0.1-0.60.50.2
Incentive Sensitization - Breakpoint0.10.10.30.2-0.20.0-0.10.1-0.1-0.40.20.1-0.0-0.60.40.1
Progressive ratio test 1 active lever presses0.80.81.31.0-1.01.20.5-0.50.6-0.51.01.0-1.2-0.61.01.0
Progressive ratio test 1 breakpoint0.91.01.61.2-1.21.20.5-0.40.6-0.71.21.1-1.2-0.81.21.0
Progressive ratio test 1 inactive lever presses1.61.72.91.6-1.61.70.7-0.60.9-0.81.61.4-1.7-0.71.51.4
Progressive ratio test 2 active lever presses0.10.20.50.3-0.30.50.10.00.1-0.50.30.4-0.5-0.50.70.4
Progressive ratio test 2 breakpoint0.30.40.80.6-0.60.90.4-0.40.5-0.20.60.8-0.9-0.30.60.8
Progressive ratio test 2 inactive lever presses0.10.20.60.0-0.00.3-0.30.3-0.2-0.70.00.1-0.3-0.70.80.1
Total sessions with >9 infusions0.10.10.4-0.20.20.10.3-0.30.20.7-0.20.1-0.10.5-0.60.1
Short access day 1 total inactive lever presses1.01.11.50.8-0.81.01.2-1.21.21.20.81.1-1.01.0-0.61.2
Short access day 10 total inactive lever presses1.11.24.50.8-0.80.9-0.30.4-0.1-1.80.80.7-0.9-1.92.10.5
Short access day 1 total infusions0.60.61.8-0.80.8-0.8-0.20.1-0.31.0-0.8-0.80.81.0-1.3-0.7
Short access day 10 total infusions0.20.20.80.0-0.00.5-0.20.3-0.2-0.80.00.1-0.5-0.90.90.1
Short access total infusions0.00.00.1-0.10.10.20.0-0.00.0-0.0-0.10.0-0.2-0.10.00.0
Short access day 1 locomotion0.60.71.3-1.11.1-0.8-0.70.7-0.80.0-1.1-0.90.80.2-0.4-0.9
Short access day 10 total locomotion0.91.01.5-1.01.0-1.0-1.21.2-1.2-0.7-1.0-1.11.0-0.40.2-1.2
Short access total locomotion0.70.71.4-1.21.2-0.6-0.80.8-0.9-0.1-1.2-1.00.60.0-0.3-1.0
Compulsive drug intake0.50.51.01.0-1.00.90.5-0.40.5-0.21.00.7-0.9-0.30.50.7
One hour access (0.3 mA shock)1.01.12.01.1-1.11.40.7-0.60.8-0.51.11.3-1.4-0.91.11.2
One hour access (shock baseline)0.30.30.70.3-0.30.70.7-0.60.70.30.30.8-0.70.00.20.8
Number of responses in last shaping day0.60.61.41.2-1.20.80.5-0.40.5-0.31.20.9-0.8-0.30.70.8
Context. condit. distance diff. score3.03.75.22.1-2.12.32.1-2.12.20.92.12.2-2.30.7-0.02.2
Locomotion velocity, session 13.03.35.4-2.02.0-2.3-1.71.6-1.8-0.1-2.0-2.22.3-0.1-1.0-2.2
Locomotion distance, session 11.01.45.1-0.00.0-0.01.1-1.21.02.2-0.00.10.02.0-2.30.2
Locomotion velocity, session 22.22.64.9-2.02.0-1.7-0.60.5-0.81.4-2.0-1.71.71.3-2.2-1.6
Locomotion distance, session 20.60.91.80.6-0.60.71.2-1.21.11.40.60.8-0.71.3-1.10.8
Locomotion velocity, session 31.31.52.5-1.31.3-1.6-1.00.9-1.10.5-1.3-1.61.60.4-1.2-1.5
Locomotion distance, session 31.11.23.5-1.11.1-1.1-0.30.2-0.41.3-1.1-1.11.11.2-1.9-1.0
Stereotopy head waving bouts, day 31.01.22.8-1.71.7-1.1-0.80.8-0.90.1-1.7-1.11.10.2-0.5-1.1
Stereotopy head waving duration, day 30.40.51.2-1.11.1-0.6-0.30.3-0.40.2-1.1-0.60.60.6-0.5-0.6
Locomotion velocity, session 70.20.21.0-0.20.2-0.10.2-0.30.20.9-0.2-0.20.10.8-1.0-0.1
Locomotion distance, session 71.51.95.70.5-0.50.51.5-1.61.42.30.50.5-0.52.3-2.40.6
Stereotopy head waving bouts, day 70.10.10.1-0.00.00.40.2-0.10.2-0.2-0.00.3-0.40.20.40.3
Stereotopy head waving duration, day 70.10.10.5-0.20.20.3-0.10.2-0.1-0.5-0.20.2-0.3-0.10.70.2
Locomotion velocity, session 81.01.32.30.6-0.61.11.5-1.51.41.40.61.0-1.11.0-1.21.0
Locomotion distance, session 84.97.310.12.8-2.82.93.2-3.23.22.02.82.9-2.91.7-0.93.0
Degree of sensitization distance1.41.42.21.5-1.51.51.2-1.21.20.11.51.4-1.5-0.00.41.3
Degree of sensitization stereotypy0.20.30.50.5-0.50.70.4-0.30.4-0.30.50.6-0.7-0.10.60.6
Condit. Reinf. active minus inactive responses1.11.22.41.2-1.21.20.5-0.40.6-0.91.21.2-1.2-1.21.51.1
Condit. Reinf. active-inactive response ratio0.50.61.11.0-1.00.70.2-0.20.4-0.61.00.7-0.7-0.61.00.7
Condit. Reinf. active responses1.92.34.41.6-1.61.80.8-0.60.9-1.21.61.8-1.8-1.42.11.7
Condit. Reinf. inactive responses0.40.51.10.5-0.50.90.4-0.40.5-0.60.50.9-0.9-0.71.10.9
Incentive salience index mean1.01.21.81.2-1.21.30.6-0.50.8-0.61.21.3-1.3-0.81.31.3
Condit. Reinf. lever presses0.50.60.80.6-0.60.90.9-0.90.90.80.60.9-0.90.6-0.30.9
Time in familiar zone, hab. session 10.30.30.5-0.30.3-0.6-0.60.6-0.6-0.5-0.3-0.60.6-0.70.2-0.6
Time in novel zone, hab. session 10.10.10.20.1-0.10.50.5-0.50.50.30.10.4-0.50.5-0.10.5
Total zone transitions, hab. session 10.20.20.70.0-0.00.10.6-0.60.50.80.00.2-0.10.6-0.80.2
Total locomotion distance, hab. session 10.60.81.20.9-0.90.91.0-1.01.10.60.91.0-0.90.3-0.11.1
Locomotion velocity, hab. session 10.71.01.31.2-1.21.01.0-1.11.10.71.21.1-1.00.4-0.11.1
Time in familiar zone, hab. session 20.20.20.40.6-0.60.20.4-0.50.40.60.60.1-0.20.7-0.60.2
Time in novel zone, hab. session 20.10.10.4-0.60.6-0.1-0.00.0-0.10.0-0.6-0.10.10.1-0.2-0.1
Total zone transitions, hab. session 22.02.64.11.5-1.51.52.0-2.01.91.71.51.6-1.51.4-1.11.6
Total locomotion distance, hab. session 23.04.05.52.0-2.02.22.3-2.32.31.32.02.3-2.21.2-0.32.3
Locomotion velocity, hab. session 23.04.05.72.1-2.12.32.2-2.22.31.02.12.4-2.30.9-0.02.4
Novel to familiar place preference ratio1.41.54.7-0.30.3-0.4-1.21.3-1.1-2.1-0.3-0.30.4-2.12.2-0.4
Novelty place preference1.51.65.0-0.40.4-0.5-1.31.4-1.2-2.2-0.4-0.40.5-2.22.1-0.5
Time in novel zone, NPP test1.11.13.9-0.20.2-0.3-1.11.1-0.9-1.9-0.2-0.30.3-2.01.9-0.4
Total zone transitions, NPP test2.84.06.21.7-1.71.72.5-2.52.42.21.71.9-1.72.1-1.61.9
Total locomotion distance, NPP test3.95.47.62.2-2.22.52.8-2.82.81.92.22.5-2.51.7-0.92.6
Locomotion velocity, NPP test2.84.05.52.0-2.02.22.3-2.32.31.42.02.2-2.21.3-0.52.3
Pavlov. Cond. lever latency1.72.13.71.2-1.21.11.8-1.91.81.81.21.2-1.11.6-1.51.2
Pavlov. Cond. magazine entry latency1.72.26.6-0.30.3-0.8-1.71.8-1.6-2.3-0.3-0.80.8-2.62.3-0.9
Pavlov. Cond. change in total contacts1.81.93.2-1.11.1-1.4-1.81.8-1.7-1.4-1.1-1.41.4-1.21.0-1.4
Pavlov. Cond. index score1.21.65.60.1-0.1-0.2-1.31.4-1.2-2.20.1-0.20.2-2.22.4-0.3
Pavlov. Cond. latency score1.41.84.8-0.50.5-0.5-1.61.7-1.5-2.1-0.5-0.60.5-2.22.2-0.7
Pavlov. Cond. lever contacts0.50.61.3-0.40.4-0.4-1.01.1-0.9-1.1-0.4-0.40.4-1.11.1-0.5
Pavlov. Cond. magazine entry number2.73.47.00.9-0.91.32.3-2.32.22.70.91.4-1.32.7-2.31.5
Pavlov. Cond. intertrial magazine entries1.21.51.91.4-1.41.41.3-1.31.30.41.41.4-1.40.60.11.4
Pavlov. Cond. lever-magazine prob. diff.1.31.65.90.1-0.1-0.2-1.31.5-1.2-2.20.1-0.20.2-2.22.4-0.3
Pavlov. Cond. response bias1.92.45.4-0.60.6-1.0-1.92.0-1.8-2.3-0.6-1.01.0-2.32.1-1.1
Bone: apparent density0.40.61.31.1-1.10.80.7-0.70.80.31.10.9-0.8-0.00.20.9
Bone surface0.10.20.40.5-0.50.40.00.00.1-0.30.50.4-0.4-0.50.60.3
Bone volume0.20.30.70.9-0.90.60.3-0.30.4-0.10.90.6-0.6-0.30.50.6
Bone: connectivity density0.60.91.30.8-0.81.11.1-1.11.10.90.81.0-1.10.6-0.51.0
Bone: cortical apparent density1.11.42.9-1.21.2-1.4-0.60.4-0.71.0-1.2-1.41.41.2-1.7-1.3
Bone: cortical area1.72.610.41.4-1.41.2-0.40.6-0.1-2.21.41.2-1.2-2.73.21.1
Bone: cortical porosity3.94.26.8-1.61.6-1.9-2.62.6-2.5-2.2-1.6-1.91.9-2.11.7-2.0
Bone: cortical porosity2.62.84.6-1.21.2-1.4-2.12.1-2.0-2.1-1.2-1.41.4-1.91.7-1.4
Bone: cortical thickness1.62.611.00.6-0.60.3-1.31.4-1.0-2.70.60.3-0.3-3.23.30.2
Bone: cortical thickness0.50.62.60.3-0.30.2-0.50.6-0.4-1.30.30.2-0.2-1.41.60.2
Bone: cortical tissue density1.31.63.3-1.31.3-1.5-0.60.5-0.71.0-1.3-1.51.51.3-1.8-1.4
Bone: elastic displacement0.40.52.10.3-0.3-0.0-0.70.7-0.5-1.20.30.00.0-1.11.4-0.0
Bone: elastic work3.03.914.00.1-0.1-0.4-2.02.2-1.7-3.40.1-0.30.4-3.63.7-0.5
Bone: endosteal estimation0.71.41.91.4-1.41.21.3-1.31.30.81.41.2-1.20.9-0.41.2
Bone: endosteal perimeter0.30.51.30.8-0.80.60.00.10.1-0.70.80.6-0.6-1.11.20.6
Bone: final force1.62.69.91.5-1.51.4-0.10.30.2-2.21.51.4-1.4-2.23.11.3
Bone: final moment1.72.912.01.5-1.51.2-0.40.5-0.1-2.51.51.3-1.2-2.43.51.1
Bone: marrow area0.71.41.91.4-1.41.21.3-1.31.30.81.41.2-1.20.9-0.41.2
Bone: maximum diameter0.40.82.60.8-0.80.90.00.10.2-0.90.80.9-0.9-1.21.60.8
Bone: maximum force1.93.210.21.9-1.91.70.20.00.4-2.21.91.7-1.7-2.33.21.5
Bone: maximum moment2.03.412.21.8-1.81.6-0.10.30.2-2.51.81.5-1.6-2.63.51.4
Bone: minimum diameter0.81.66.41.0-1.00.9-0.40.5-0.1-1.61.01.0-0.9-2.12.50.9
Bone: periosteal estimation0.91.83.51.7-1.71.40.5-0.40.7-1.01.71.4-1.4-1.21.91.4
Bone: periosteal perimeter1.21.97.40.2-0.20.0-1.31.4-1.1-2.30.20.0-0.0-2.72.7-0.1
Bone: post-yield work0.50.71.10.7-0.70.91.0-1.01.00.60.70.9-0.90.5-0.40.9
Bone: stiffness0.40.61.01.0-1.01.00.4-0.40.5-0.51.00.9-1.0-0.61.00.9
Bone: tissue strength1.41.42.21.3-1.31.51.0-0.91.10.01.31.5-1.50.00.71.5
Bone: trabecular number0.10.10.30.5-0.50.20.2-0.20.20.10.50.2-0.2-0.1-0.00.2
Bone: trabecular spacing3.44.46.02.1-2.12.32.4-2.42.51.42.12.3-2.31.5-0.52.3
Bone: trabecular thickness2.12.53.8-1.31.3-1.5-1.92.0-1.9-1.7-1.3-1.41.5-1.91.3-1.5
Bone: trabecular tissue density0.30.41.2-0.80.8-0.6-0.10.0-0.20.7-0.8-0.60.60.9-1.1-0.6
Breakpoint value in progressive ratio session0.80.92.0-0.50.5-0.7-1.21.2-1.1-1.4-0.5-0.80.7-1.41.1-0.8
Distance traveled before self-admin1.01.13.60.1-0.1-0.0-1.21.2-1.0-1.80.1-0.50.0-1.91.6-0.6
Distance traveled after self-admin0.80.92.01.4-1.41.00.8-0.70.80.11.41.0-1.0-0.10.51.0
Delta time in closed arm before/after self-admin0.20.20.50.3-0.30.20.5-0.50.50.70.30.5-0.20.7-0.40.5
Delta time in open arm before/after self-admin0.20.20.30.5-0.50.30.4-0.50.50.20.50.3-0.30.2-0.10.4
Diff in mean of infusions in LGA sessions0.20.20.4-0.50.5-0.4-0.50.4-0.50.1-0.5-0.70.40.1-0.3-0.6
Extinction: sum of active levers before priming1.01.01.9-1.01.0-1.1-0.90.8-0.90.3-1.0-1.41.10.3-0.9-1.3
Active lever presses in extinction session 61.51.52.3-1.01.0-1.5-1.51.4-1.4-0.6-1.0-1.51.5-0.80.1-1.5
Delta distance traveled before/after self-admin1.21.32.30.9-0.90.61.4-1.41.41.50.91.0-0.61.5-1.11.0
Delta ambulatory time before/after self-admin1.21.33.70.4-0.40.21.3-1.41.21.90.40.7-0.21.9-1.60.7
Time in closed arm before self-admin1.11.32.3-1.51.5-1.0-1.11.1-1.1-0.8-1.5-1.11.0-0.80.2-1.2
Time in closed arm after self-admin2.72.83.9-2.02.0-1.8-1.71.7-1.8-0.9-2.0-1.91.8-0.8-0.0-1.9
Time in open arm before self-admin0.40.41.10.5-0.50.40.7-0.60.61.00.50.5-0.41.0-0.70.6
Time in open arm after self-admin0.60.61.10.8-0.80.50.9-0.90.91.00.80.7-0.51.0-0.70.7
Sum of active levers in priming session hrs 5-60.90.82.3-0.40.4-0.7-1.01.0-0.9-1.5-0.4-0.60.7-1.51.2-0.6
Time to tail flick, vehicle, before self-admin0.10.10.20.0-0.00.40.4-0.30.40.10.00.4-0.40.10.10.4
Time to tail flick, vehicle, after self-admin0.91.02.9-1.11.1-0.80.1-0.20.01.5-1.1-0.60.81.4-1.7-0.5
Time to tail flick, test, before self-admin0.30.20.4-0.50.5-0.6-0.50.5-0.5-0.6-0.5-0.30.6-0.60.4-0.4
Time to tail flick, test, after self-admin0.20.20.4-0.40.4-0.7-0.20.2-0.30.4-0.4-0.40.70.3-0.5-0.4
Delta time to tail flick, vehicle, before/after SA0.50.41.40.4-0.40.20.7-0.70.71.20.40.4-0.21.1-0.90.4
Delta time to tail flick, test, before/after SA0.50.40.8-0.70.7-0.8-0.60.6-0.60.1-0.7-0.90.80.1-0.5-0.8
Ambulatory time before self-admin1.21.24.60.4-0.40.3-1.01.0-0.8-2.00.4-0.1-0.3-2.12.0-0.2
Ambulatory time after self-admin0.40.40.80.9-0.90.70.4-0.40.5-0.10.90.6-0.7-0.20.50.6
Total heroin consumption1.01.32.0-0.70.7-1.3-1.41.4-1.4-1.2-0.7-1.21.3-0.90.6-1.2
Area under the delay curve0.60.61.8-0.80.8-0.8-0.10.0-0.20.8-0.8-0.70.81.2-1.3-0.7
Delay disc. indifference point, 0s delay0.00.00.5-0.10.1-0.10.1-0.10.00.1-0.1-0.10.10.7-0.2-0.0
Delay disc. indifference point, 16s delay1.41.44.80.8-0.80.31.3-1.41.11.80.80.5-0.32.2-1.80.6
Delay disc. indifference point, 2s delay0.40.40.7-0.80.8-0.7-0.40.4-0.50.1-0.8-0.60.70.7-0.5-0.6
Delay disc. indifference point, 24s delay2.82.84.2-2.02.0-2.0-1.00.9-1.20.9-2.0-2.02.00.7-2.0-1.9
Delay disc. indifference point, 4s delay0.40.41.0-1.01.0-0.6-0.40.3-0.40.4-1.0-0.60.60.6-0.6-0.5
Delay disc. indifference point, 8s delay1.01.01.6-1.31.3-1.1-0.90.8-1.0-0.2-1.3-1.21.10.0-0.6-1.2
Delay discount exponential model param1.01.12.11.2-1.21.10.4-0.30.6-0.71.21.1-1.1-1.11.51.1
Delay discount hyperbolic model param1.01.12.11.3-1.31.10.4-0.30.5-0.71.31.1-1.1-1.21.41.0
Fecal boli incidents, locomotor time 10.20.21.0-0.00.0-0.20.4-0.40.31.0-0.00.00.20.7-1.00.1
Change in fecal boli incidents, locomotor task3.33.14.6-2.12.1-2.0-1.71.7-1.8-0.4-2.1-2.22.0-0.3-0.6-2.1
Time >=10cm from walls, locomotor time 11.81.82.71.4-1.41.61.5-1.51.50.41.41.6-1.60.60.11.6
Bouts of movement, locomotor time 10.70.81.7-1.01.0-1.1-0.30.2-0.40.8-1.0-1.01.10.4-1.3-0.9
Total resting periods, locomotor time 11.21.42.1-1.41.4-1.4-0.70.6-0.80.7-1.4-1.41.40.2-1.3-1.3
Rest time, locomotor task time 10.60.71.0-0.80.8-1.0-1.00.9-0.9-0.2-0.8-1.01.0-0.6-0.1-1.0
Distance moved, locomotor task time 10.80.81.81.3-1.31.00.7-0.70.8-0.11.31.0-1.00.40.50.9
Vertical activity count, locomotor time 12.22.34.22.0-2.01.71.4-1.31.40.12.01.7-1.70.80.61.7
Time >=10cm from walls, locomotor time 20.10.10.3-0.30.30.50.4-0.30.30.0-0.30.4-0.50.5-0.00.4
Bouts of movement, locomotor time 20.30.41.6-0.60.6-0.30.3-0.40.21.0-0.6-0.30.30.7-1.3-0.3
Total resting periods, locomotor time 20.40.41.4-0.20.20.10.7-0.70.61.2-0.20.2-0.10.8-1.20.2
Rest time, locomotor task time 20.00.00.1-0.20.2-0.1-0.10.1-0.10.1-0.2-0.20.10.0-0.2-0.2
Distance moved, locomotor task time 20.10.10.50.6-0.60.20.2-0.20.20.00.60.2-0.20.70.00.2
Vertical activity count, locomotor time 21.21.31.81.4-1.41.11.3-1.21.20.71.41.2-1.11.2-0.21.2
Weight adjusted by age0.91.03.41.0-1.00.6-0.20.3-0.1-1.41.00.6-0.6-1.81.80.5
Seeking ratio, delayed vs. immediate footshock0.70.81.50.9-0.91.10.4-0.30.5-0.80.91.0-1.1-0.71.21.0
Locomotion in novel chamber0.30.30.50.7-0.70.40.7-0.70.60.50.70.3-0.40.6-0.60.3
Locomotion in novel chamber post-restriction0.81.03.10.4-0.41.20.10.10.2-1.40.40.9-1.2-1.61.70.7
Progressive ratio0.20.20.5-0.50.5-0.5-0.20.2-0.20.5-0.5-0.50.50.6-0.7-0.4
Food seeking constrained by brief footshock0.50.61.0-0.70.7-1.0-0.90.9-0.9-0.5-0.7-1.01.0-0.2-0.0-1.0
Seeking ratio, punishment vs. effort0.10.10.20.4-0.40.30.2-0.20.3-0.30.40.4-0.3-0.20.40.4
Run reversals in cocaine runway, females0.60.61.30.4-0.40.21.1-1.11.01.00.40.5-0.21.1-1.00.6
Run reversals in cocaine runway, males1.31.33.4-0.60.6-0.4-1.31.4-1.3-1.8-0.6-0.60.4-1.71.6-0.7
Latency to leave start box in cocaine runway0.20.30.90.1-0.10.20.5-0.50.50.90.10.3-0.21.0-0.70.3
Latency to leave start box in cocaine runway, F1.11.22.60.5-0.51.01.3-1.31.31.60.51.0-1.01.4-1.11.1
Latency to leave start box in cocaine runway, M0.10.10.3-0.30.3-0.2-0.40.4-0.4-0.6-0.3-0.30.2-0.30.4-0.3
Cd content in liver0.50.52.3-0.40.4-0.40.4-0.50.21.2-0.4-0.40.41.4-1.5-0.3
Co content in liver0.10.10.40.0-0.0-0.10.2-0.20.20.60.00.00.10.5-0.50.1
Cu content in liver1.41.62.7-1.11.1-1.3-1.61.7-1.5-1.3-1.1-1.21.3-1.31.0-1.2
Fe content in liver0.30.41.50.1-0.1-0.30.3-0.30.21.00.1-0.30.31.2-1.2-0.2
K content in liver1.81.83.21.3-1.31.81.2-1.11.30.01.31.8-1.8-0.40.91.8
Mg content in liver2.82.93.91.6-1.62.02.0-1.92.01.21.62.0-2.01.0-0.42.0
Mn content in liver0.10.10.3-0.10.10.1-0.20.2-0.1-0.5-0.10.1-0.1-0.60.60.1
Na content in liver0.00.00.1-0.10.1-0.1-0.10.2-0.10.0-0.1-0.10.1-0.40.0-0.1
Rb content in liver1.41.72.71.6-1.61.61.3-1.21.3-0.11.61.6-1.6-0.00.61.5
Se content in liver0.20.30.50.7-0.70.60.4-0.30.4-0.20.70.6-0.6-0.40.50.6
Sr content in liver3.22.93.7-1.91.9-1.9-1.91.9-1.9-1.3-1.9-1.91.9-1.00.5-1.9
Zn content in liver0.20.30.9-0.90.9-0.3-0.30.4-0.30.2-0.9-0.20.3-0.1-0.1-0.3