Hub : Genes

Notum

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000036680 0.19 0.12 3.3e-06 0.14 0.11 0.11 0.12 8.9e-08 1.9e-06 1.2e-06 5.5e-07
2 Brain gene expression ENSRNOG00000036680 0.21 0.11 2.4e-15 0.18 0.15 0.16 0.17 1.0e-16 1.2e-13 1.3e-14 1.5e-15
3 Brain mRNA stability ENSRNOG00000036680 0.03 0.02 2.2e-03 0.03 0.03 0.03 0.03 1.4e-03 4.3e-04 7.8e-04 8.1e-04
4 IL gene expression ENSRNOG00000036680 0.24 0.14 2.2e-03 0.06 0.02 0.03 0.04 1.8e-02 1.0e-01 5.7e-02 4.4e-02
5 LHb gene expression ENSRNOG00000036680 0.21 0.13 8.9e-03 0 0.02 -0.01 0.01 2.4e-01 8.8e-02 6.7e-01 1.7e-01
6 Liver gene expression ENSRNOG00000036680 0.11 0.06 2.1e-11 0.1 0.1 0.09 0.09 5.3e-11 2.5e-11 1.3e-10 1.8e-10
7 Liver mRNA stability ENSRNOG00000036680 0.03 0.03 3.2e-03 0.02 0.01 0.02 0.01 5.4e-03 2.3e-02 3.6e-03 8.6e-03
8 NAcc gene expression ENSRNOG00000036680 0.06 0.04 3.1e-03 0.03 0.03 0.02 0.03 1.7e-03 5.8e-03 1.1e-02 3.6e-03
9 OFC gene expression ENSRNOG00000036680 0.32 0.16 2.3e-04 0.04 0 0.05 0.04 3.2e-02 2.5e-01 2.5e-02 3.7e-02
10 PL gene expression ENSRNOG00000036680 0.2 0.11 4.3e-10 0.13 0.13 0.12 0.14 2.3e-10 8.6e-10 4.1e-09 1.4e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.62.03.92.02.01.21.41.40.20.01.61.31.6
BMI without tail6.613.720.14.44.33.14.53.90.90.34.24.24.2
Body weight1.87.617.03.43.44.12.51.8-1.52.52.82.02.7
Epididymis fat weight1.02.44.92.22.21.41.41.40.10.41.91.21.8
Glucose7.311.117.0-3.7-3.7-1.3-4.1-3.9-2.00.7-3.9-4.0-3.9
Heart weight0.10.20.80.40.50.90.10.1-0.50.30.30.20.3
Left kidney weight0.10.40.7-0.8-0.80.3-0.4-0.6-0.80.8-0.4-0.6-0.5
Right kidney weight0.00.10.2-0.5-0.5-0.1-0.2-0.2-0.1-0.10.1-0.20.1
Tail length3.811.316.93.73.64.14.13.1-0.41.93.73.73.6
Length with tail0.93.110.51.61.73.21.20.4-2.02.71.20.81.1
Length without tail2.35.18.4-2.2-1.9-0.2-2.8-2.7-2.11.5-2.5-2.9-2.5
Liver weight, left1.01.62.7-1.2-1.10.0-1.6-1.6-1.20.6-1.4-1.6-1.4
Liver weight, right0.71.23.90.90.91.80.80.4-1.02.00.80.40.7
Parametrial fat weight0.81.53.71.61.61.91.00.6-0.91.21.00.81.0
Retroperitoneal fat weight2.37.715.13.73.73.92.21.8-1.42.22.91.92.8
Intraocular pressure0.50.71.40.80.81.01.20.90.10.10.91.10.9
Extensor digitorum longus weight0.93.75.22.32.3-0.12.02.11.7-1.42.12.12.1
Soleus weight0.72.04.01.31.32.01.61.1-0.51.31.61.31.5
Tibialis anterior weight0.30.91.51.01.10.01.21.10.9-0.41.11.21.0
Tibia length2.87.832.40.80.95.70.8-0.5-4.34.90.80.10.7
Number of licking bursts0.50.60.90.80.90.10.90.90.6-0.21.00.90.9
Food consumed during 24 hour testing period0.20.20.50.50.50.70.50.4-0.20.70.50.40.5
Times rat made contact with spout1.31.53.6-0.7-0.81.4-0.7-1.1-1.91.9-0.9-0.9-0.9
Mean time between licks in bursts0.50.72.7-0.6-0.6-1.7-0.4-0.11.0-1.4-0.5-0.3-0.5
Mean num. licks in bursts0.91.12.0-0.9-1.00.7-0.9-1.2-1.41.1-1.1-1.1-1.1
Std. dev. time between licks in bursts4.85.87.72.72.80.22.62.82.0-1.52.72.72.7
Water consumed over 24 hours0.91.11.4-1.2-1.20.0-1.1-1.1-0.90.9-1.1-1.1-1.1
Indifference point 0 sec0.00.10.20.40.50.30.20.0-0.30.10.10.10.1
Indifference point AUC0.10.10.30.20.20.00.50.30.3-0.40.50.50.5
Indifference point function ln k0.30.41.5-0.2-0.2-1.2-0.6-0.10.7-0.8-0.5-0.5-0.5
Indifference point function log k0.30.41.5-0.2-0.2-1.2-0.6-0.10.7-0.8-0.5-0.5-0.5
Delay discounting total patch changes 0 sec0.10.10.40.60.70.30.30.2-0.1-0.10.20.30.2
Delay discounting total patch changes 12 sec0.00.10.2-0.2-0.10.30.1-0.3-0.40.2-0.2-0.1-0.2
Delay discounting total patch changes 18 sec0.71.02.01.31.4-0.40.80.80.9-1.40.70.90.7
Delay discounting total patch changes 24 sec0.40.61.81.31.40.80.70.5-0.20.20.40.50.4
Delay discounting total patch changes 6 sec0.10.20.7-0.3-0.20.80.2-0.2-0.80.8-0.00.0-0.0
Delay discounting time to switch 0 sec0.30.40.7-0.8-0.8-0.8-0.6-0.50.2-0.3-0.8-0.5-0.8
Delay discounting water rate 0 sec1.62.63.91.92.01.91.71.4-0.20.61.91.51.9
Delay discounting water rate 12 sec1.01.52.41.51.50.31.11.30.9-0.81.41.31.4
Delay discounting water rate 18 sec1.62.23.71.91.90.61.41.70.9-0.21.81.41.8
Delay discounting water rate 24 sec3.34.68.82.93.01.32.02.30.9-0.72.52.02.5
Delay discounting water rate 6 sec0.50.71.41.21.20.10.60.90.7-0.21.00.71.0
Locomotor activity0.30.51.2-0.4-0.5-1.1-0.8-0.50.3-0.6-0.9-0.8-0.8
Locomotor testing distance0.30.62.10.00.1-1.5-0.50.11.0-1.3-0.5-0.5-0.4
Locomotor testing rearing0.20.31.10.30.3-0.9-0.10.40.9-1.1-0.0-0.10.0
Light reinforcement 11.73.25.61.92.01.01.92.00.8-0.32.42.02.4
Light reinforcement 21.51.93.41.41.51.51.41.40.00.91.81.31.8
Reaction time number correct6.18.711.93.23.3-0.52.83.43.1-3.03.03.13.0
Reaction time mean minus median0.70.91.6-0.9-1.0-0.1-1.2-1.1-0.80.5-0.9-1.3-0.9
Reaction time mean minus median AUC0.10.10.2-0.2-0.30.0-0.4-0.4-0.30.2-0.1-0.5-0.2
Reaction time num false alarms0.20.31.0-1.0-1.0-0.6-0.3-0.20.2-0.3-0.5-0.2-0.5
Reaction time num false alarms AUC0.30.41.1-0.9-0.9-1.0-0.3-0.10.6-0.7-0.5-0.2-0.5
Reaction time trials correct on left6.18.711.93.23.3-0.52.83.43.1-3.03.03.13.0
Reaction time trials on left6.39.012.33.33.4-0.52.83.53.2-3.03.03.23.0
Reaction time mean0.20.30.70.80.80.50.40.4-0.0-0.20.80.40.8
Reaction time mean AUC0.60.81.51.11.10.30.80.90.4-0.61.20.81.2
Median of all reaction times0.50.71.21.11.10.50.80.80.3-0.41.10.81.1
Reaction time omissions0.30.40.90.90.90.00.70.70.5-0.30.70.50.7
Reaction time false alarm rate2.23.16.3-2.5-2.5-0.6-1.7-1.8-1.00.9-1.9-1.7-1.9
Reaction time premature initiation rate0.70.91.6-1.1-1.2-1.3-0.5-0.50.5-0.6-1.2-0.5-1.2
Reaction time premature initiations1.21.74.70.70.7-1.41.11.42.1-2.20.51.20.6
Std. dev. reaction times0.10.10.5-0.0-0.1-0.7-0.4-0.20.3-0.7-0.1-0.3-0.1
Reaction time trials completed6.39.012.33.33.4-0.52.83.53.2-3.03.03.23.0
Reaction time trials AUC6.39.112.33.33.4-0.52.83.53.1-3.03.03.23.1
Social response proportion0.20.20.70.20.1-0.80.20.40.8-0.8-0.10.2-0.1
Social responses0.20.20.50.60.7-0.60.10.40.6-0.20.20.10.2
Social time0.10.10.40.20.1-0.50.30.50.7-0.50.20.20.2
Conditioned locomotion3.54.26.22.52.52.22.31.90.00.52.32.12.3
Cocaine response after cond. corrected0.40.50.8-0.8-0.8-0.0-0.7-0.8-0.60.1-0.9-0.8-0.9
Cocaine response after cond. not corrected0.60.61.1-1.0-1.0-0.6-0.7-0.8-0.2-0.2-1.0-0.8-1.0
Cocaine response before conditioning0.30.41.5-0.2-0.2-1.20.20.41.1-0.70.10.20.1
Saline control response1.31.74.41.31.32.11.30.9-0.81.31.31.11.2
Condit. Reinf. active minus inactive responses0.50.71.30.80.81.21.00.7-0.20.60.90.80.9
Condit. Reinf. active-inactive response ratio0.70.83.30.30.31.80.60.0-1.21.40.40.40.4
Condit. Reinf. active responses0.40.50.70.80.80.60.80.70.3-0.20.80.80.8
Condit. Reinf. inactive responses0.20.31.30.30.2-0.80.00.30.9-1.10.20.20.2
Condit. Reinf. lever presses0.70.91.61.31.20.31.11.00.6-0.71.01.01.0
Condit. Reinf. lever reinforcers received0.60.81.31.11.10.51.01.00.5-0.51.01.01.0
Pavlov. Cond. lever latency1.52.03.8-1.9-1.9-0.6-1.5-1.5-0.80.7-1.6-1.4-1.6
Pavlov. Cond. magazine entry latency1.11.33.90.60.6-1.70.50.91.9-2.00.40.60.5
Pavlov. Cond. change in total contacts0.71.02.21.21.2-0.60.71.01.2-1.50.80.80.8
Pavlov. Cond. index score0.71.01.81.21.1-0.50.81.01.2-1.40.80.80.8
Pavlov. Cond. latency score1.01.31.91.31.3-0.51.01.21.3-1.41.01.01.0
Pavlov. Cond. lever contacts2.12.95.12.32.20.81.81.80.9-0.81.91.71.9
Pavlov. Cond. magazine entry number1.11.33.7-0.9-0.81.5-0.6-1.0-1.81.9-0.5-0.7-0.6
Pavlov. Cond. intertrial magazine entries0.81.12.71.01.01.61.10.7-0.50.71.21.01.1
Pavlov. Cond. lever-magazine prob. diff.0.81.02.21.11.1-0.70.71.01.3-1.50.70.80.7
Pavlov. Cond. response bias1.21.62.81.71.70.01.21.41.1-1.21.31.21.3
Conditioned reinforcement - actives0.50.51.00.50.5-0.20.60.90.8-0.51.00.61.0
Conditioned reinforcement - inactives0.50.61.90.60.61.40.50.1-0.91.30.50.30.5
Conditioned locomotion0.10.10.30.50.50.10.20.40.20.10.60.10.5
Intermittent access intake day 1-15 change0.40.41.20.20.21.10.5-0.0-0.80.90.50.30.5
Intermittent access intake escalation0.30.30.90.20.21.00.70.3-0.40.70.60.50.6
Intermittent access intake escalation 21.11.14.2-0.3-0.31.7-0.0-0.7-1.82.1-0.0-0.4-0.0
Intermitt. access day 1 inactive lever presses0.40.51.70.60.51.30.2-0.3-1.11.10.1-0.00.1
Intermitt. access day 15 inactive lever presses1.01.22.31.51.40.91.21.10.20.61.11.01.1
Intermitt. access escalation Index1.71.52.31.41.40.61.51.50.8-0.21.41.51.4
Intermittent access day 1 total infusions0.30.30.50.60.60.70.60.5-0.1-0.00.70.60.7
Intermittent access day 15 total infusions0.50.61.10.70.80.90.90.7-0.10.21.00.81.0
Intermittent access terminal intake (last 3 days)0.50.61.70.60.71.30.70.4-0.50.80.90.60.9
Intermittent access total infusions0.40.50.80.60.60.90.80.6-0.10.20.90.80.9
Intermittent access day 1 locomotion0.50.50.90.90.80.50.80.80.3-0.10.90.70.9
Intermittent access day 15 total locomotion0.20.20.6-0.0-0.00.80.30.0-0.50.50.40.10.4
Intermittent access total locomotion0.30.30.60.50.50.70.60.4-0.20.40.70.40.7
Intermittent access standard deviation2.12.23.2-1.6-1.7-0.1-1.6-1.8-1.41.1-1.4-1.8-1.4
Cocaine induced anxiety2.73.110.40.20.12.7-0.6-1.5-3.13.2-0.5-1.0-0.5
Post-drug Anxiety1.01.12.9-0.1-0.11.0-0.7-1.2-1.61.7-0.8-0.9-0.8
Baseline Anxiety2.52.79.9-1.1-1.2-3.2-0.60.22.3-2.5-0.9-0.3-0.9
Lifetime Intake0.20.20.40.30.30.40.40.40.00.10.60.40.6
Incentive Sensitization - Responses0.10.10.40.20.30.60.70.2-0.20.10.10.50.1
Incentive Sensitization - Breakpoint0.10.10.30.10.20.50.50.1-0.20.10.00.3-0.0
Progressive ratio test 1 active lever presses0.80.81.31.11.01.10.90.8-0.20.41.20.81.1
Progressive ratio test 1 breakpoint1.01.01.71.21.21.30.90.8-0.30.51.21.01.2
Progressive ratio test 1 inactive lever presses1.81.93.11.81.61.71.31.1-0.30.61.71.21.7
Progressive ratio test 2 active lever presses0.20.20.60.30.30.80.60.3-0.30.40.50.40.5
Progressive ratio test 2 breakpoint0.40.50.90.50.60.80.90.70.00.20.90.80.8
Progressive ratio test 2 inactive lever presses0.20.20.70.10.00.80.3-0.1-0.60.70.30.00.2
Total sessions with >9 infusions0.10.10.3-0.2-0.2-0.6-0.00.20.6-0.40.10.10.1
Short access day 1 total inactive lever presses0.80.91.40.90.8-0.41.01.21.2-1.01.00.81.0
Short access day 10 total inactive lever presses1.31.44.90.90.82.21.10.3-1.31.60.90.80.8
Short access day 1 total infusions0.70.82.1-0.8-0.8-1.4-1.0-0.50.6-0.8-0.8-0.8-0.8
Short access day 10 total infusions0.20.20.80.00.00.90.1-0.0-0.70.80.50.10.5
Short access total infusions0.00.00.1-0.1-0.10.0-0.00.00.00.10.20.10.2
Short access day 1 locomotion0.60.71.3-1.1-1.1-0.6-1.0-0.9-0.30.1-0.8-0.9-0.8
Short access day 10 total locomotion0.80.91.5-0.9-1.0-0.0-1.0-1.2-0.90.8-1.0-1.1-1.0
Short access total locomotion0.60.61.4-1.1-1.2-0.5-0.9-0.9-0.40.3-0.6-0.9-0.7
Compulsive drug intake0.50.51.01.01.00.60.60.60.00.10.90.50.9
One hour access (0.3 mA shock)1.11.32.01.01.11.31.31.0-0.10.51.41.21.4
One hour access (shock baseline)0.30.40.70.20.30.30.90.80.40.00.70.80.7
Number of responses in last shaping day0.60.61.71.31.20.80.60.6-0.10.50.80.60.7
Context. condit. distance diff. score3.03.75.32.12.10.32.12.21.5-0.92.32.32.3
Locomotion velocity, session 13.13.45.4-2.0-2.0-1.3-2.2-2.0-0.60.1-2.3-2.0-2.3
Locomotion distance, session 11.01.34.5-0.0-0.0-2.10.20.61.9-2.0-0.00.50.0
Locomotion velocity, session 22.32.75.8-2.1-2.0-2.4-1.5-1.20.8-1.0-1.7-1.4-1.7
Locomotion distance, session 20.60.92.10.60.6-0.90.91.01.4-1.20.71.00.7
Locomotion velocity, session 31.51.82.8-1.4-1.3-1.4-1.7-1.3-0.1-0.6-1.6-1.5-1.6
Locomotion distance, session 31.31.44.1-1.2-1.1-2.0-1.2-0.70.8-1.2-1.1-1.0-1.1
Stereotopy head waving bouts, day 31.01.22.9-1.7-1.7-0.7-1.1-1.0-0.3-0.1-1.1-1.0-1.1
Stereotopy head waving duration, day 30.40.41.2-1.1-1.1-0.6-0.6-0.50.0-0.3-0.6-0.5-0.6
Locomotion velocity, session 70.20.21.1-0.3-0.2-1.1-0.3-0.00.6-0.6-0.1-0.2-0.1
Locomotion distance, session 71.51.95.80.50.5-2.20.41.02.3-2.40.50.80.6
Stereotopy head waving bouts, day 70.10.10.1-0.0-0.00.40.20.2-0.10.30.40.20.4
Stereotopy head waving duration, day 70.10.20.7-0.2-0.20.70.10.0-0.50.80.30.00.3
Locomotion velocity, session 81.01.32.80.60.6-0.91.11.31.7-1.11.11.21.1
Locomotion distance, session 84.87.29.72.82.8-0.32.93.12.7-2.02.93.12.9
Degree of sensitization distance1.51.52.21.51.50.61.41.30.7-0.31.51.41.5
Degree of sensitization stereotypy0.30.30.50.50.50.70.50.5-0.10.50.70.40.7
Condit. Reinf. active minus inactive responses1.31.42.91.21.21.71.30.9-0.51.21.21.11.2
Condit. Reinf. active-inactive response ratio0.50.61.11.01.01.10.70.5-0.40.70.70.60.7
Condit. Reinf. active responses2.32.85.61.61.62.41.91.3-0.51.51.81.71.8
Condit. Reinf. inactive responses0.60.71.50.60.51.21.10.7-0.20.90.91.00.9
Incentive salience index mean1.21.42.21.21.21.51.41.0-0.21.21.31.21.3
Condit. Reinf. lever presses0.40.60.80.70.6-0.20.90.90.8-0.10.90.90.9
Time in familiar zone, hab. session 10.20.20.4-0.3-0.30.1-0.6-0.6-0.50.2-0.6-0.5-0.6
Time in novel zone, hab. session 10.10.10.20.10.1-0.10.40.50.4-0.20.50.40.5
Total zone transitions, hab. session 10.20.20.80.00.0-0.70.20.40.8-0.90.10.30.2
Total locomotion distance, hab. session 10.50.71.10.90.9-0.00.91.00.7-0.30.90.91.0
Locomotion velocity, hab. session 10.60.81.41.21.20.00.91.10.7-0.31.00.91.0
Time in familiar zone, hab. session 20.20.20.40.60.6-0.60.10.30.6-0.60.20.20.2
Time in novel zone, hab. session 20.10.10.4-0.6-0.6-0.1-0.1-0.10.1-0.2-0.1-0.0-0.1
Total zone transitions, hab. session 21.92.54.01.41.5-0.81.71.82.0-1.61.51.81.5
Total locomotion distance, hab. session 22.93.95.72.02.00.12.42.41.8-0.92.22.42.3
Locomotion velocity, hab. session 22.94.05.82.12.10.42.42.41.6-0.72.32.42.3
Novel to familiar place preference ratio1.31.44.3-0.3-0.32.0-0.4-0.8-2.02.1-0.4-0.6-0.4
Novelty place preference1.41.54.3-0.4-0.42.0-0.5-0.9-2.02.1-0.5-0.7-0.5
Time in novel zone, NPP test1.01.03.1-0.3-0.21.8-0.3-0.7-1.71.8-0.3-0.5-0.3
Total zone transitions, NPP test2.63.76.51.71.7-1.21.92.22.5-2.11.72.11.7
Total locomotion distance, NPP test3.65.07.22.22.2-0.42.52.72.4-1.62.52.62.5
Locomotion velocity, NPP test2.63.75.32.02.0-0.12.12.31.8-1.22.22.22.2
Pavlov. Cond. lever latency1.72.25.41.11.2-1.21.11.52.1-2.31.11.31.1
Pavlov. Cond. magazine entry latency1.62.16.7-0.3-0.32.1-0.7-1.2-2.42.6-0.8-0.9-0.8
Pavlov. Cond. change in total contacts1.81.93.2-1.1-1.10.7-1.4-1.6-1.81.5-1.4-1.6-1.4
Pavlov. Cond. index score1.41.87.10.10.12.2-0.2-0.8-2.22.7-0.2-0.5-0.2
Pavlov. Cond. latency score1.51.97.4-0.4-0.52.0-0.5-1.1-2.22.7-0.5-0.8-0.6
Pavlov. Cond. lever contacts0.60.72.9-0.4-0.41.0-0.4-0.7-1.31.7-0.4-0.6-0.4
Pavlov. Cond. magazine entry number2.53.17.80.90.9-2.01.31.82.8-2.71.31.51.3
Pavlov. Cond. intertrial magazine entries1.31.52.11.41.40.31.41.40.9-0.61.41.41.4
Pavlov. Cond. lever-magazine prob. diff.1.41.87.00.20.12.3-0.2-0.8-2.22.6-0.2-0.5-0.3
Pavlov. Cond. response bias1.92.36.4-0.6-0.61.8-0.9-1.5-2.42.5-1.0-1.2-1.0
Bone: apparent density0.40.61.31.11.10.30.90.80.4-0.20.80.80.8
Bone surface0.10.20.40.50.50.60.40.2-0.30.60.40.30.4
Bone volume0.20.40.70.80.90.60.70.5-0.10.40.60.60.6
Bone: connectivity density0.60.91.30.80.8-0.31.11.11.1-0.61.11.11.1
Bone: cortical apparent density1.31.73.6-1.2-1.2-1.9-1.5-1.10.5-1.3-1.4-1.3-1.4
Bone: cortical area2.13.110.51.41.43.21.20.4-2.02.91.20.71.1
Bone: cortical porosity3.84.17.2-1.7-1.61.3-1.9-2.3-2.72.3-1.9-2.2-2.0
Bone: cortical porosity2.62.85.6-1.3-1.21.4-1.4-1.8-2.42.1-1.4-1.7-1.5
Bone: cortical thickness1.72.910.30.60.63.20.4-0.4-2.63.20.3-0.10.2
Bone: cortical thickness0.50.62.40.30.31.60.2-0.1-1.21.30.20.00.2
Bone: cortical tissue density1.62.04.1-1.3-1.3-2.0-1.6-1.10.5-1.4-1.5-1.4-1.5
Bone: elastic displacement0.50.51.90.30.31.40.0-0.3-1.21.2-0.0-0.2-0.0
Bone: elastic work2.93.812.30.10.13.5-0.3-1.2-3.43.5-0.4-0.8-0.4
Bone: endosteal estimation0.61.41.91.41.4-0.21.21.31.1-1.01.21.21.2
Bone: endosteal perimeter0.30.61.40.80.81.20.60.3-0.61.10.60.40.6
Bone: final force1.93.110.51.61.53.21.40.7-1.72.41.41.01.3
Bone: final moment2.03.412.31.51.53.51.30.5-2.12.71.20.81.2
Bone: marrow area0.61.31.91.41.4-0.21.11.31.1-1.11.21.21.2
Bone: maximum diameter0.61.02.80.80.81.70.80.5-0.91.60.90.60.9
Bone: maximum force2.13.711.31.91.93.41.71.0-1.52.21.71.41.7
Bone: maximum moment2.23.913.11.81.83.61.60.8-1.92.51.61.21.5
Bone: minimum diameter1.12.06.31.01.02.50.90.3-1.62.40.90.50.8
Bone: periosteal estimation1.02.04.01.71.72.01.41.0-0.71.31.41.21.4
Bone: periosteal perimeter1.32.18.30.20.22.6-0.0-0.6-2.32.90.0-0.4-0.0
Bone: post-yield work0.50.70.90.70.7-0.20.91.01.0-0.70.90.90.9
Bone: stiffness0.50.71.21.01.01.10.90.7-0.20.51.00.80.9
Bone: tissue strength1.51.52.31.31.31.01.51.30.30.21.51.41.5
Bone: trabecular number0.10.10.30.50.50.00.30.20.2-0.00.20.30.2
Bone: trabecular spacing3.24.15.72.12.1-0.12.22.41.9-1.42.32.32.3
Bone: trabecular thickness1.92.34.1-1.3-1.31.0-1.4-1.7-2.01.7-1.5-1.5-1.5
Bone: trabecular tissue density0.40.51.3-0.8-0.8-1.1-0.7-0.40.5-0.8-0.6-0.5-0.6
Breakpoint value in progressive ratio session0.80.92.1-0.4-0.50.8-0.8-1.1-1.41.2-0.7-1.0-0.7
Distance traveled before self-admin1.11.14.7-0.00.11.4-0.7-0.9-1.72.2-0.0-0.7-0.1
Distance traveled after self-admin0.90.92.01.41.40.71.00.90.3-0.11.01.01.0
Delta time in closed arm before/after self-admin0.20.20.40.30.3-0.30.50.50.6-0.30.20.40.2
Delta time in open arm before/after self-admin0.10.10.30.50.5-0.1-0.00.30.3-0.40.30.10.4
Diff in mean of infusions in LGA sessions0.30.30.9-0.4-0.5-0.5-0.9-0.6-0.20.1-0.4-0.9-0.4
Extinction: sum of active levers before priming1.31.33.1-1.0-1.0-1.2-1.8-1.2-0.2-0.3-1.1-1.5-1.1
Active lever presses in extinction session 61.81.73.3-0.9-1.0-0.3-1.7-1.6-1.10.7-1.5-1.8-1.5
Delta distance traveled before/after self-admin1.21.33.71.00.9-0.80.91.31.6-1.90.61.10.6
Delta ambulatory time before/after self-admin1.21.35.00.50.4-1.40.71.11.8-2.20.20.80.3
Time in closed arm before self-admin0.91.02.3-1.5-1.50.0-1.0-1.2-0.90.5-1.0-0.9-0.9
Time in closed arm after self-admin2.32.44.1-2.0-2.0-0.3-1.5-1.8-1.20.7-1.8-1.6-1.8
Time in open arm before self-admin0.30.30.70.50.5-0.60.40.60.8-0.50.40.30.4
Time in open arm after self-admin0.40.40.90.80.8-0.60.30.80.9-0.90.50.40.5
Sum of active levers in priming session hrs 5-60.70.71.9-0.2-0.41.1-0.4-0.8-1.41.2-0.7-0.6-0.6
Time to tail flick, vehicle, before self-admin0.10.10.20.00.00.20.40.40.2-0.30.40.40.4
Time to tail flick, vehicle, after self-admin0.90.93.0-1.1-1.1-1.7-0.7-0.21.0-0.9-0.8-0.6-0.8
Time to tail flick, test, before self-admin0.20.20.4-0.6-0.50.40.2-0.3-0.50.5-0.6-0.0-0.6
Time to tail flick, test, after self-admin0.20.20.5-0.3-0.4-0.6-0.5-0.40.1-0.0-0.7-0.6-0.7
Delta time to tail flick, vehicle, before/after SA0.30.31.00.40.4-0.80.30.61.0-0.60.20.30.2
Delta time to tail flick, test, before/after SA0.60.61.4-0.5-0.7-0.7-1.2-0.8-0.2-0.2-0.8-1.1-0.8
Ambulatory time before self-admin1.21.35.10.10.41.8-0.3-0.6-1.82.30.3-0.40.3
Ambulatory time after self-admin0.30.40.80.90.90.50.50.50.00.20.70.60.7
Total heroin consumption1.21.52.5-0.8-0.70.3-1.4-1.5-1.41.3-1.3-1.6-1.3
Area under the delay curve0.70.71.9-0.9-0.8-1.4-0.7-0.40.6-1.1-0.8-0.6-0.7
Delay disc. indifference point, 0s delay0.00.00.1-0.1-0.1-0.3-0.2-0.00.1-0.3-0.1-0.2-0.1
Delay disc. indifference point, 16s delay1.31.35.00.60.8-1.70.30.91.8-2.20.30.50.4
Delay disc. indifference point, 2s delay0.30.40.7-0.7-0.8-0.6-0.6-0.5-0.0-0.1-0.7-0.7-0.7
Delay disc. indifference point, 24s delay3.33.25.0-2.1-2.0-2.2-1.9-1.60.3-1.0-2.0-1.9-1.9
Delay disc. indifference point, 4s delay0.30.41.0-0.9-1.0-0.6-0.4-0.40.1-0.4-0.6-0.5-0.5
Delay disc. indifference point, 8s delay0.90.91.6-1.3-1.3-0.7-1.0-1.1-0.3-0.1-1.1-1.0-1.1
Delay discount exponential model param1.11.22.41.31.21.61.00.8-0.51.11.10.91.1
Delay discount hyperbolic model param1.11.22.41.31.31.51.00.7-0.51.11.10.91.1
Fecal boli incidents, locomotor time 10.20.20.9-0.1-0.0-0.9-0.10.20.8-0.7-0.2-0.1-0.2
Change in fecal boli incidents, locomotor task3.12.94.6-2.1-2.1-0.9-1.9-2.0-0.9-0.0-2.0-1.8-2.0
Time >=10cm from walls, locomotor time 12.02.03.71.31.40.51.81.71.0-0.81.61.91.6
Bouts of movement, locomotor time 10.91.12.1-1.1-1.0-1.4-1.2-0.70.5-0.9-1.1-1.0-1.0
Total resting periods, locomotor time 11.51.62.3-1.5-1.4-1.5-1.5-1.10.2-0.7-1.4-1.4-1.4
Rest time, locomotor task time 10.60.71.2-0.8-0.8-0.3-0.9-1.0-0.60.4-1.0-1.1-1.0
Distance moved, locomotor task time 10.70.81.81.21.30.70.80.80.2-0.21.00.91.0
Vertical activity count, locomotor time 12.02.14.21.92.00.81.31.50.7-0.31.71.51.7
Time >=10cm from walls, locomotor time 20.20.20.4-0.4-0.30.10.60.40.3-0.20.50.60.5
Bouts of movement, locomotor time 20.40.51.5-0.6-0.6-1.2-0.40.00.9-1.2-0.3-0.2-0.3
Total resting periods, locomotor time 20.40.41.5-0.3-0.2-1.10.00.51.1-1.20.10.20.1
Rest time, locomotor task time 20.00.00.1-0.2-0.2-0.2-0.2-0.10.1-0.1-0.1-0.3-0.2
Distance moved, locomotor task time 20.10.10.40.50.60.10.20.20.1-0.30.20.30.2
Vertical activity count, locomotor time 21.11.21.81.31.4-0.01.11.21.0-0.81.11.21.1
Weight adjusted by age0.91.13.21.21.01.80.40.1-1.21.60.60.20.6
Seeking ratio, delayed vs. immediate footshock0.91.01.91.00.91.41.10.8-0.41.11.10.91.0
Locomotion in novel chamber0.30.41.00.70.7-0.6-0.00.40.8-1.00.40.20.5
Locomotion in novel chamber post-restriction1.01.23.70.50.41.91.20.6-0.81.31.21.11.2
Progressive ratio0.20.20.6-0.4-0.5-0.8-0.5-0.30.2-0.1-0.5-0.5-0.4
Food seeking constrained by brief footshock0.60.71.1-0.7-0.7-0.2-1.0-1.0-0.70.4-1.0-1.0-1.0
Seeking ratio, punishment vs. effort0.10.10.20.40.40.40.40.3-0.1-0.10.30.40.3
Run reversals in cocaine runway, females0.70.73.30.30.4-0.90.40.81.3-1.80.20.70.3
Run reversals in cocaine runway, males1.21.23.7-0.5-0.61.4-0.5-1.0-1.81.9-0.4-0.8-0.4
Latency to leave start box in cocaine runway0.20.20.70.10.1-0.60.20.50.8-0.90.20.30.3
Latency to leave start box in cocaine runway, F1.01.12.30.50.5-0.90.91.21.5-1.41.00.91.0
Latency to leave start box in cocaine runway, M0.10.10.2-0.4-0.30.4-0.1-0.3-0.50.5-0.20.0-0.2
Cd content in liver0.50.62.3-0.4-0.4-1.5-0.4-0.01.0-1.4-0.4-0.2-0.3
Co content in liver0.10.10.30.00.0-0.5-0.10.10.3-0.6-0.1-0.1-0.1
Cu content in liver1.41.72.7-1.1-1.10.7-1.2-1.4-1.61.6-1.3-1.4-1.3
Fe content in liver0.30.41.60.10.1-1.3-0.4-0.00.8-1.1-0.3-0.3-0.3
K content in liver2.02.03.61.31.31.21.91.60.30.41.81.71.7
Mg content in liver2.82.94.41.51.6-0.12.12.11.6-1.02.02.12.0
Mn content in liver0.10.10.7-0.2-0.10.60.20.0-0.40.80.10.10.1
Na content in liver0.00.00.1-0.1-0.1-0.0-0.2-0.1-0.10.3-0.1-0.2-0.2
Rb content in liver1.51.92.81.51.60.91.71.50.6-0.21.61.61.6
Se content in liver0.30.30.50.60.70.60.60.50.00.40.60.60.6
Sr content in liver3.22.93.8-1.9-1.90.1-1.9-2.0-1.61.3-1.9-1.9-1.9
Zn content in liver0.20.20.9-1.0-0.9-0.1-0.0-0.2-0.10.5-0.3-0.1-0.3