Hub : Genes

Tbcd

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000036658 0.49 0.1 0.0e+00 0.37 0.39 0.4 0.34 2.7e-43 6.1e-46 3.0e-47 5.8e-39
2 Adipose mRNA stability ENSRNOG00000036658 0.1 0.05 1.5e-06 0.04 0.06 0.05 0.03 2.4e-05 6.6e-07 2.4e-06 9.2e-05
3 BLA mRNA stability ENSRNOG00000036658 0.12 0.07 2.8e-05 0.09 0.07 0.06 0.07 1.5e-05 8.0e-05 4.1e-04 1.0e-04
4 Brain intron excision ratio chr10:106868314:106868880 0.04 0.02 1.4e-05 0.02 0.04 0.04 0.05 2.9e-03 8.6e-05 2.4e-04 2.9e-05
5 Brain mRNA stability ENSRNOG00000036658 0.03 0.02 2.2e-03 0.02 0.02 0.02 0.02 2.4e-03 5.2e-03 5.5e-03 4.9e-03
6 Liver gene expression ENSRNOG00000036658 0.11 0.05 2.6e-14 0.11 0.11 0.1 0.04 4.9e-12 1.6e-12 1.2e-11 1.7e-05
7 NAcc gene expression ENSRNOG00000036658 0.09 0.04 3.8e-07 0.06 0.07 0.07 -0 1.7e-05 1.1e-05 1.1e-05 6.5e-01
8 PL gene expression ENSRNOG00000036658 0.05 0.03 4.8e-04 0.03 0.04 0.03 0.03 3.2e-03 7.8e-04 1.4e-03 1.3e-03
9 PL intron excision ratio chr10:106868989:106870530 0.04 0.02 1.0e-03 0.05 0.04 0.04 0.01 1.4e-04 6.2e-04 9.3e-04 7.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.41.32.8-1.3-1.71.11.01.2-0.6-1.3-0.91.1
BMI without tail4.69.513.5-3.0-1.83.32.73.2-3.2-3.6-3.73.0
Body weight3.012.620.6-3.7-4.53.33.63.5-2.8-3.6-3.63.0
Epididymis fat weight0.51.21.7-1.0-0.71.11.11.1-1.1-1.3-1.31.0
Glucose3.35.07.22.41.0-2.6-1.4-2.52.02.32.5-2.7
Heart weight1.42.03.6-1.5-1.91.31.51.5-1.1-1.6-1.11.1
Left kidney weight0.20.74.2-0.8-2.00.30.60.4-0.2-0.7-0.30.1
Right kidney weight0.10.42.7-0.6-1.70.10.30.30.3-0.40.1-0.1
Tail length4.613.820.4-3.5-2.53.83.63.8-4.0-4.1-4.53.4
Length with tail1.86.710.0-2.5-3.22.32.82.4-2.3-2.6-2.82.0
Length without tail0.61.31.90.7-1.2-1.3-0.4-1.11.41.21.3-1.2
Liver weight, left0.20.30.50.6-0.0-0.7-0.1-0.60.50.50.5-0.7
Liver weight, right1.22.02.8-1.4-1.71.41.41.3-1.3-1.5-1.51.4
Parametrial fat weight1.32.43.4-1.4-0.31.61.81.6-1.8-1.8-1.61.6
Retroperitoneal fat weight4.013.116.5-3.5-3.03.53.63.7-3.8-3.9-4.13.4
Intraocular pressure0.91.32.1-1.1-1.21.10.91.1-1.1-1.3-1.51.0
Extensor digitorum longus weight0.20.81.4-1.0-0.41.00.31.0-0.9-1.2-1.00.9
Soleus weight1.95.66.8-2.6-2.02.42.22.4-2.4-2.4-2.32.5
Tibialis anterior weight0.20.71.2-0.9-0.10.90.50.9-1.1-1.1-0.90.8
Tibia length11.532.560.7-6.1-7.85.36.05.2-4.5-5.4-5.15.3
Number of licking bursts0.20.20.4-0.40.00.60.20.6-0.4-0.6-0.40.7
Food consumed during 24 hour testing period0.50.60.9-0.7-0.30.80.70.7-1.0-0.8-0.80.9
Times rat made contact with spout1.61.83.9-1.0-0.31.31.51.1-2.0-1.4-1.31.5
Mean time between licks in bursts2.43.43.61.91.9-1.8-1.9-1.81.81.81.8-1.9
Mean num. licks in bursts0.20.30.7-0.4-0.40.30.70.2-0.8-0.4-0.50.4
Std. dev. time between licks in bursts0.30.30.6-0.6-0.20.70.20.8-0.2-0.6-0.80.6
Water consumed over 24 hours0.00.00.10.00.1-0.00.1-0.2-0.30.00.20.0
Indifference point 0 sec0.00.00.00.00.0-0.1-0.0-0.20.00.2-0.1-0.2
Indifference point AUC0.10.20.5-0.30.50.30.20.5-0.4-0.4-0.20.7
Indifference point function ln k0.81.12.00.80.0-1.0-1.0-0.91.41.01.1-1.4
Indifference point function log k0.81.12.00.80.0-1.0-1.0-0.91.41.01.1-1.4
Delay discounting total patch changes 0 sec0.00.00.00.0-0.0-0.1-0.0-0.10.10.2-0.1-0.2
Delay discounting total patch changes 12 sec0.10.10.70.20.8-0.2-0.0-0.1-0.10.10.1-0.0
Delay discounting total patch changes 18 sec0.10.10.30.20.5-0.2-0.4-0.20.30.30.2-0.1
Delay discounting total patch changes 24 sec0.20.20.4-0.5-0.30.40.40.4-0.4-0.2-0.50.6
Delay discounting total patch changes 6 sec0.30.40.7-0.6-0.20.60.70.6-0.7-0.6-0.60.8
Delay discounting time to switch 0 sec0.40.61.01.00.9-0.7-0.8-0.90.50.60.7-0.9
Delay discounting water rate 0 sec0.61.01.6-1.1-0.81.01.21.0-0.7-0.8-1.31.0
Delay discounting water rate 12 sec0.00.00.1-0.2-0.30.20.20.30.4-0.1-0.10.1
Delay discounting water rate 18 sec0.50.61.3-1.0-1.20.80.51.0-0.3-0.7-0.80.7
Delay discounting water rate 24 sec0.91.22.6-1.3-1.61.10.91.1-0.6-1.0-1.30.9
Delay discounting water rate 6 sec0.20.31.20.3-0.1-0.4-0.2-0.41.10.50.5-0.7
Locomotor activity0.91.52.01.41.2-1.2-1.2-1.21.21.11.2-1.4
Locomotor testing distance0.71.21.71.10.9-1.1-1.3-1.11.00.91.1-1.3
Locomotor testing rearing0.81.32.81.31.7-1.0-1.2-1.00.81.00.9-1.2
Light reinforcement 11.12.03.0-1.5-0.41.41.11.6-1.7-1.7-1.51.2
Light reinforcement 21.62.12.6-1.6-0.91.51.41.6-1.5-1.6-1.51.3
Reaction time number correct0.10.20.3-0.40.20.5-0.40.50.1-0.4-0.40.2
Reaction time mean minus median0.40.61.00.91.0-0.8-0.4-0.70.40.70.7-0.8
Reaction time mean minus median AUC0.00.00.10.20.3-0.2-0.0-0.20.10.20.2-0.1
Reaction time num false alarms0.00.10.10.10.1-0.2-0.4-0.3-0.00.10.2-0.3
Reaction time num false alarms AUC0.20.30.50.50.6-0.5-0.7-0.60.40.40.6-0.6
Reaction time trials correct on left0.10.20.3-0.40.20.5-0.40.50.1-0.4-0.40.2
Reaction time trials on left0.10.10.3-0.40.20.5-0.40.50.1-0.4-0.40.2
Reaction time mean0.20.30.4-0.4-0.00.50.60.5-0.6-0.6-0.50.5
Reaction time mean AUC0.20.30.5-0.5-0.10.70.50.6-0.6-0.7-0.60.6
Median of all reaction times0.30.30.5-0.6-0.20.70.60.6-0.6-0.7-0.60.6
Reaction time omissions0.10.10.70.20.80.1-0.2-0.10.00.10.00.1
Reaction time false alarm rate0.20.30.60.60.4-0.7-0.5-0.80.20.60.7-0.6
Reaction time premature initiation rate0.91.11.91.21.4-1.0-0.9-1.00.90.81.1-1.2
Reaction time premature initiations0.50.61.70.81.3-0.5-1.0-0.50.80.50.7-0.9
Std. dev. reaction times0.30.41.00.81.0-0.6-0.5-0.60.50.50.6-0.5
Reaction time trials completed0.10.10.3-0.40.20.5-0.40.50.1-0.4-0.40.2
Reaction time trials AUC0.10.20.4-0.50.10.6-0.30.6-0.0-0.5-0.50.3
Social response proportion1.51.62.41.30.7-1.3-1.3-1.51.51.41.1-1.3
Social responses0.50.61.10.60.2-0.8-0.8-0.81.00.80.8-0.9
Social time0.10.10.30.2-0.2-0.2-0.4-0.40.60.20.4-0.4
Conditioned locomotion5.36.37.3-2.6-2.22.62.32.6-2.4-2.6-2.72.5
Cocaine response after cond. corrected0.40.40.60.70.4-0.7-0.4-0.70.60.80.6-0.7
Cocaine response after cond. not corrected1.11.21.71.20.9-1.2-0.9-1.21.11.21.0-1.3
Cocaine response before conditioning0.70.81.20.90.9-0.9-1.1-0.71.00.80.9-1.0
Saline control response2.63.44.3-1.9-1.81.91.91.9-1.7-1.6-2.02.1
Condit. Reinf. active minus inactive responses2.32.86.2-1.9-2.51.51.41.6-1.3-1.5-1.61.5
Condit. Reinf. active-inactive response ratio4.24.46.9-2.2-2.61.92.12.0-2.0-2.0-2.01.9
Condit. Reinf. active responses0.71.02.7-1.1-1.70.80.70.8-0.7-0.8-1.00.8
Condit. Reinf. inactive responses0.50.71.00.70.3-0.8-1.0-0.91.00.90.7-0.7
Condit. Reinf. lever presses0.20.30.7-0.6-0.40.60.40.6-0.4-0.6-0.60.9
Condit. Reinf. lever reinforcers received0.60.82.1-1.0-1.40.80.60.8-0.7-0.9-1.00.8
Pavlov. Cond. lever latency0.81.11.61.00.6-1.1-0.7-1.01.11.21.2-1.3
Pavlov. Cond. magazine entry latency2.02.34.71.72.2-1.3-1.7-1.41.31.21.3-1.3
Pavlov. Cond. change in total contacts0.10.10.40.30.2-0.3-0.6-0.30.20.20.0-0.2
Pavlov. Cond. index score0.10.20.70.50.9-0.2-0.6-0.30.20.10.1-0.0
Pavlov. Cond. latency score0.10.10.60.30.8-0.1-0.5-0.20.0-0.1-0.10.1
Pavlov. Cond. lever contacts1.21.72.5-1.3-0.81.30.91.3-1.4-1.4-1.51.6
Pavlov. Cond. magazine entry number1.72.14.6-1.6-2.11.21.61.3-1.3-1.2-1.11.1
Pavlov. Cond. intertrial magazine entries2.63.44.8-2.0-2.21.81.81.8-1.5-1.7-1.81.8
Pavlov. Cond. lever-magazine prob. diff.0.20.31.10.71.1-0.4-0.7-0.50.30.20.2-0.2
Pavlov. Cond. response bias0.10.10.3-0.10.30.3-0.10.2-0.3-0.4-0.50.5
Conditioned reinforcement - actives0.10.10.3-0.10.50.2-0.20.4-0.0-0.1-0.10.5
Conditioned reinforcement - inactives0.10.10.5-0.10.00.40.70.3-0.2-0.3-0.50.4
Conditioned locomotion0.00.10.20.00.10.4-0.40.30.10.0-0.20.3
Intermittent access intake day 1-15 change0.10.10.40.10.30.20.40.0-0.4-0.1-0.60.2
Intermittent access intake escalation0.10.10.40.20.60.30.1-0.0-0.4-0.1-0.60.3
Intermittent access intake escalation 20.10.10.50.0-0.10.10.60.0-0.5-0.1-0.70.2
Intermitt. access day 1 inactive lever presses0.10.10.4-0.1-0.4-0.20.70.2-0.4-0.3-0.60.0
Intermitt. access day 15 inactive lever presses0.60.61.0-0.7-0.90.80.70.8-0.5-0.7-1.00.9
Intermitt. access escalation Index1.31.21.7-1.2-0.41.30.61.0-1.3-1.1-1.21.2
Intermittent access day 1 total infusions0.91.01.5-0.9-0.81.20.81.1-0.9-1.1-1.01.1
Intermittent access day 15 total infusions0.50.50.9-0.5-0.10.90.50.7-0.8-0.6-0.90.9
Intermittent access terminal intake (last 3 days)0.60.71.1-0.6-0.11.00.70.7-1.0-0.8-1.10.9
Intermittent access total infusions0.70.71.1-0.8-0.51.00.71.0-0.8-0.8-1.01.0
Intermittent access day 1 locomotion0.00.00.1-0.0-0.20.0-0.10.30.1-0.1-0.30.1
Intermittent access day 15 total locomotion0.20.20.5-0.3-0.70.30.30.6-0.4-0.3-0.70.5
Intermittent access total locomotion0.00.00.20.0-0.3-0.1-0.00.30.00.0-0.40.1
Intermittent access standard deviation2.32.53.51.91.0-1.7-0.9-1.81.71.71.5-1.7
Cocaine induced anxiety0.91.02.7-0.9-1.60.71.60.5-0.9-0.5-1.00.5
Post-drug Anxiety0.20.20.50.3-0.5-0.60.2-0.50.30.60.2-0.7
Baseline Anxiety4.24.56.22.01.6-2.2-2.5-1.92.42.02.2-2.1
Lifetime Intake0.10.10.2-0.20.10.50.20.4-0.4-0.3-0.40.5
Incentive Sensitization - Responses0.80.81.4-0.7-0.30.71.00.9-1.1-1.2-1.00.8
Incentive Sensitization - Breakpoint0.60.61.2-0.6-0.30.50.90.8-1.0-1.1-0.90.7
Progressive ratio test 1 active lever presses0.60.61.3-0.7-0.60.70.60.9-1.0-0.7-1.10.7
Progressive ratio test 1 breakpoint1.21.32.1-1.0-0.91.00.91.3-1.4-1.1-1.51.0
Progressive ratio test 1 inactive lever presses1.01.11.6-1.0-0.91.20.91.2-0.9-0.9-1.31.1
Progressive ratio test 2 active lever presses0.30.30.7-0.3-0.30.30.60.6-0.8-0.7-0.80.5
Progressive ratio test 2 breakpoint0.40.50.9-0.5-0.30.40.70.8-0.9-0.9-1.00.6
Progressive ratio test 2 inactive lever presses0.10.10.2-0.1-0.50.00.30.2-0.3-0.1-0.40.2
Total sessions with >9 infusions0.30.30.50.60.5-0.4-0.7-0.40.60.50.5-0.7
Short access day 1 total inactive lever presses0.10.10.50.20.7-0.1-0.3-0.10.0-0.20.00.1
Short access day 10 total inactive lever presses1.31.43.4-1.0-1.10.71.81.1-1.1-1.3-1.40.8
Short access day 1 total infusions2.42.52.91.61.5-1.5-1.6-1.71.51.51.7-1.6
Short access day 10 total infusions0.20.20.4-0.2-0.10.60.40.3-0.6-0.4-0.60.4
Short access total infusions0.00.00.30.20.5-0.1-0.1-0.10.00.10.1-0.2
Short access day 1 locomotion0.60.71.00.80.3-0.9-0.7-1.00.80.81.0-0.8
Short access day 10 total locomotion0.70.81.40.90.5-1.2-0.6-0.60.91.00.9-1.0
Short access total locomotion0.70.71.50.80.3-1.2-0.7-0.60.90.80.9-1.0
Compulsive drug intake0.80.81.0-0.9-0.90.91.01.0-0.7-1.0-0.70.8
One hour access (0.3 mA shock)1.61.92.4-1.2-0.61.31.41.5-1.5-1.5-1.51.6
One hour access (shock baseline)0.60.71.2-0.7-0.00.90.50.9-0.9-0.9-0.91.1
Number of responses in last shaping day0.10.10.5-0.4-0.70.20.30.5-0.1-0.2-0.40.3
Context. condit. distance diff. score0.50.60.9-0.8-0.00.90.40.9-0.8-0.9-1.00.9
Locomotion velocity, session 11.71.92.81.31.1-1.4-1.1-1.41.21.51.7-1.4
Locomotion distance, session 11.31.72.81.11.0-1.2-1.7-1.21.51.21.5-1.1
Locomotion velocity, session 24.65.46.12.41.9-2.3-2.3-2.32.52.52.5-2.3
Locomotion distance, session 20.10.10.50.10.1-0.2-0.6-0.00.70.30.30.1
Locomotion velocity, session 32.73.24.21.70.9-1.8-1.6-1.82.12.11.9-1.7
Locomotion distance, session 34.95.36.92.31.6-2.4-2.3-2.32.62.52.4-2.2
Stereotopy head waving bouts, day 30.20.20.40.3-0.1-0.4-0.3-0.50.50.40.7-0.4
Stereotopy head waving duration, day 30.00.00.10.0-0.4-0.1-0.1-0.10.20.00.3-0.2
Locomotion velocity, session 71.01.11.51.00.9-1.0-1.2-1.11.01.11.0-1.0
Locomotion distance, session 73.54.56.02.12.4-1.9-2.4-1.92.12.12.0-2.0
Stereotopy head waving bouts, day 70.60.61.2-0.8-1.10.70.70.7-0.7-0.9-0.70.8
Stereotopy head waving duration, day 70.80.91.8-1.0-1.30.90.90.9-0.9-1.0-0.90.9
Locomotion velocity, session 80.20.20.60.1-0.2-0.3-0.7-0.20.80.50.4-0.2
Locomotion distance, session 80.30.50.9-0.8-0.30.9-0.01.0-0.2-0.8-0.81.0
Degree of sensitization distance0.70.71.2-0.80.11.00.61.0-1.1-1.0-1.00.8
Degree of sensitization stereotypy0.60.71.1-0.8-1.00.80.70.7-0.7-0.9-0.80.8
Condit. Reinf. active minus inactive responses2.62.93.2-1.8-1.71.71.71.7-1.7-1.7-1.81.6
Condit. Reinf. active-inactive response ratio1.21.33.2-1.3-1.81.01.01.0-0.9-1.0-1.10.9
Condit. Reinf. active responses4.45.36.1-2.3-1.72.42.32.4-2.4-2.4-2.52.3
Condit. Reinf. inactive responses1.11.31.8-0.9-0.01.21.11.1-1.3-1.3-1.21.2
Incentive salience index mean1.82.22.6-1.5-1.21.51.41.5-1.5-1.5-1.61.4
Condit. Reinf. lever presses0.10.10.80.30.9-0.1-0.4-0.1-0.00.0-0.0-0.1
Time in familiar zone, hab. session 10.00.00.10.20.1-0.10.1-0.20.10.10.2-0.1
Time in novel zone, hab. session 10.00.00.0-0.10.20.1-0.10.2-0.1-0.0-0.00.1
Total zone transitions, hab. session 10.20.20.50.40.5-0.4-0.5-0.30.70.40.6-0.3
Total locomotion distance, hab. session 10.30.40.6-0.6-0.30.70.40.8-0.3-0.8-0.40.7
Locomotion velocity, hab. session 10.30.40.8-0.6-0.40.80.50.9-0.4-0.9-0.50.8
Time in familiar zone, hab. session 20.50.51.40.81.2-0.6-0.7-0.60.40.60.6-0.7
Time in novel zone, hab. session 20.10.10.3-0.2-0.6-0.00.00.10.30.10.10.1
Total zone transitions, hab. session 20.10.20.4-0.40.10.5-0.10.6-0.0-0.5-0.20.6
Total locomotion distance, hab. session 21.11.42.2-1.2-0.41.40.71.5-1.0-1.5-1.11.4
Locomotion velocity, hab. session 21.52.03.0-1.5-0.71.61.01.7-1.2-1.7-1.41.6
Novel to familiar place preference ratio2.62.84.5-1.7-2.11.51.91.5-1.5-1.5-1.51.6
Novelty place preference2.72.84.8-1.8-2.21.51.91.5-1.5-1.5-1.41.6
Time in novel zone, NPP test2.22.33.7-1.6-1.91.41.81.3-1.3-1.3-1.31.5
Total zone transitions, NPP test0.10.10.60.10.60.0-0.80.10.40.00.10.1
Total locomotion distance, NPP test0.30.40.7-0.40.40.7-0.00.8-0.3-0.8-0.60.8
Locomotion velocity, NPP test0.40.60.9-0.70.00.90.20.9-0.6-0.9-0.81.0
Pavlov. Cond. lever latency0.50.71.50.80.7-0.7-1.2-0.81.00.70.6-0.7
Pavlov. Cond. magazine entry latency1.21.52.9-1.2-1.41.11.71.0-1.4-1.1-1.20.9
Pavlov. Cond. change in total contacts0.00.00.20.1-0.1-0.10.5-0.1-0.10.00.1-0.3
Pavlov. Cond. index score2.12.74.2-1.6-1.51.62.01.6-1.8-1.6-1.61.4
Pavlov. Cond. latency score1.62.13.4-1.4-1.31.41.91.3-1.7-1.4-1.41.3
Pavlov. Cond. lever contacts0.40.50.8-0.6-0.40.60.90.6-0.8-0.7-0.60.6
Pavlov. Cond. magazine entry number1.01.22.91.01.3-0.9-1.7-0.91.21.01.0-0.7
Pavlov. Cond. intertrial magazine entries0.50.50.8-0.7-0.10.80.50.8-0.8-0.9-0.80.9
Pavlov. Cond. lever-magazine prob. diff.2.12.64.1-1.6-1.71.52.01.5-1.7-1.5-1.61.4
Pavlov. Cond. response bias0.81.02.3-0.9-1.10.81.50.8-1.1-0.9-0.90.7
Bone: apparent density0.30.50.8-0.9-0.80.70.40.6-0.6-0.6-0.60.9
Bone surface0.51.01.3-1.0-1.10.90.70.8-1.1-1.0-1.10.9
Bone volume0.40.71.0-0.9-0.80.90.60.7-1.0-0.9-0.90.9
Bone: connectivity density0.10.10.4-0.5-0.30.4-0.10.4-0.3-0.3-0.40.6
Bone: cortical apparent density3.34.35.02.12.0-2.1-1.9-2.02.12.22.2-2.0
Bone: cortical area7.611.528.1-3.8-5.33.13.33.2-2.0-3.0-2.83.1
Bone: cortical porosity0.30.30.9-0.3-1.00.21.00.1-0.6-0.4-0.30.1
Bone: cortical porosity0.60.61.4-0.6-1.10.61.20.5-0.9-0.8-0.60.5
Bone: cortical thickness6.110.127.7-3.6-5.32.83.33.0-1.4-2.6-2.22.9
Bone: cortical thickness1.92.25.4-1.7-2.31.31.71.5-0.5-1.2-0.81.5
Bone: cortical tissue density3.85.05.72.32.3-2.2-2.1-2.22.22.32.4-2.2
Bone: elastic displacement1.71.93.1-1.6-1.81.31.51.4-1.0-1.2-1.11.2
Bone: elastic work7.810.218.3-3.5-4.32.93.63.0-2.6-2.9-2.62.9
Bone: endosteal estimation0.00.10.30.0-0.00.1-0.3-0.1-0.5-0.4-0.6-0.2
Bone: endosteal perimeter0.91.83.2-1.3-1.81.21.01.0-1.5-1.3-1.60.9
Bone: final force6.09.922.7-3.5-4.82.93.12.9-2.0-2.9-2.72.9
Bone: final moment7.011.525.7-3.8-5.13.13.43.1-2.3-3.1-3.03.1
Bone: marrow area0.00.10.30.1-0.00.0-0.3-0.2-0.5-0.4-0.5-0.2
Bone: maximum diameter1.83.49.3-2.0-3.11.61.61.6-1.2-1.6-1.71.5
Bone: maximum force6.711.724.9-3.7-5.03.23.43.2-2.3-3.2-3.13.2
Bone: maximum moment7.713.427.7-4.0-5.33.43.63.4-2.6-3.5-3.33.3
Bone: minimum diameter3.56.412.5-2.8-3.52.32.52.3-2.1-2.4-2.42.1
Bone: periosteal estimation2.55.111.9-2.4-3.42.02.02.0-1.7-2.2-2.21.9
Bone: periosteal perimeter3.65.915.0-2.6-3.92.12.42.0-2.0-2.2-2.21.9
Bone: post-yield work0.00.00.3-0.1-0.50.0-0.3-0.10.1-0.1-0.20.1
Bone: stiffness0.91.54.9-1.2-2.21.01.11.0-0.3-1.2-0.91.2
Bone: tissue strength1.71.63.7-1.5-1.91.21.01.2-0.7-1.2-1.31.1
Bone: trabecular number0.10.10.3-0.5-0.10.40.10.3-0.4-0.2-0.20.6
Bone: trabecular spacing0.10.10.3-0.10.10.3-0.30.30.0-0.4-0.50.3
Bone: trabecular thickness0.30.30.8-0.6-0.80.40.90.2-0.8-0.4-0.30.4
Bone: trabecular tissue density1.01.41.91.40.9-1.2-1.2-1.21.21.21.1-1.2
Breakpoint value in progressive ratio session0.70.71.81.10.3-0.9-0.4-1.40.70.90.5-1.0
Distance traveled before self-admin0.60.62.1-0.7-1.50.60.80.5-0.5-0.3-0.70.6
Distance traveled after self-admin0.30.30.6-0.20.70.70.20.6-0.7-0.5-0.80.7
Delta time in closed arm before/after self-admin0.10.10.30.20.6-0.5-0.1-0.20.00.00.2-0.4
Delta time in open arm before/after self-admin0.30.30.60.70.7-0.5-0.6-0.40.50.60.4-0.6
Diff in mean of infusions in LGA sessions1.31.41.81.31.1-1.3-1.3-1.30.81.30.9-1.2
Extinction: sum of active levers before priming2.02.03.41.41.0-1.3-1.3-1.61.51.61.9-1.2
Active lever presses in extinction session 63.83.75.52.00.7-2.0-1.7-2.12.12.31.8-2.0
Delta distance traveled before/after self-admin0.90.94.40.92.1-0.5-1.2-0.40.40.70.5-0.5
Delta ambulatory time before/after self-admin1.71.96.81.32.6-0.9-1.8-0.80.71.10.9-1.0
Time in closed arm before self-admin0.10.10.20.2-0.5-0.0-0.3-0.30.50.50.30.0
Time in closed arm after self-admin1.01.01.61.20.5-1.2-0.6-1.31.01.21.0-1.0
Time in open arm before self-admin0.20.30.6-0.8-0.30.30.20.6-0.7-0.7-0.30.5
Time in open arm after self-admin0.10.10.40.10.3-0.4-0.70.00.10.20.3-0.4
Sum of active levers in priming session hrs 5-60.10.10.40.60.5-0.00.3-0.6-0.00.2-0.0-0.3
Time to tail flick, vehicle, before self-admin0.40.41.0-0.6-0.50.90.60.7-0.3-0.5-0.51.0
Time to tail flick, vehicle, after self-admin1.01.11.70.90.7-1.1-1.3-0.91.20.91.3-1.0
Time to tail flick, test, before self-admin0.20.20.60.50.8-0.3-0.4-0.00.40.70.0-0.4
Time to tail flick, test, after self-admin1.61.72.31.31.3-1.0-1.3-1.21.51.51.3-1.1
Delta time to tail flick, vehicle, before/after SA0.30.31.20.41.1-0.6-0.7-0.20.20.10.5-0.6
Delta time to tail flick, test, before/after SA0.90.81.50.90.4-0.8-0.7-1.21.00.91.2-0.8
Ambulatory time before self-admin1.31.33.8-1.2-1.91.01.40.9-0.8-0.7-1.11.0
Ambulatory time after self-admin0.10.10.20.00.50.3-0.30.3-0.30.1-0.30.2
Total heroin consumption0.50.71.10.6-0.9-0.6-0.7-1.10.91.00.7-0.7
Area under the delay curve2.12.23.01.51.2-1.2-1.5-1.51.71.71.5-1.3
Delay disc. indifference point, 0s delay0.10.10.3-0.1-0.5-0.30.0-0.00.40.20.3-0.2
Delay disc. indifference point, 16s delay2.02.12.81.51.7-0.9-1.6-1.51.71.41.4-1.1
Delay disc. indifference point, 2s delay0.50.60.80.80.4-0.9-0.7-0.70.80.80.7-0.9
Delay disc. indifference point, 24s delay5.35.16.72.31.6-2.0-2.4-2.62.42.62.4-1.9
Delay disc. indifference point, 4s delay0.50.51.20.40.0-0.6-0.7-0.51.11.10.8-0.6
Delay disc. indifference point, 8s delay1.21.32.21.10.6-1.1-0.9-1.31.31.51.2-1.0
Delay discount exponential model param2.93.14.3-1.7-1.41.41.81.8-2.0-2.1-1.81.6
Delay discount hyperbolic model param2.72.94.0-1.6-1.31.41.81.7-2.0-2.0-1.81.5
Fecal boli incidents, locomotor time 10.20.20.50.40.7-0.3-0.7-0.20.30.10.4-0.3
Change in fecal boli incidents, locomotor task3.53.34.01.91.9-1.9-1.5-2.01.41.91.8-2.0
Time >=10cm from walls, locomotor time 10.60.61.4-0.8-0.51.20.40.6-0.7-0.6-1.01.0
Bouts of movement, locomotor time 10.60.71.30.80.8-0.7-0.8-0.80.80.61.2-0.7
Total resting periods, locomotor time 10.80.91.80.90.9-0.8-0.9-1.01.00.81.3-0.7
Rest time, locomotor task time 10.00.10.10.30.3-0.30.0-0.30.1-0.10.3-0.3
Distance moved, locomotor task time 10.20.30.70.50.5-0.4-0.5-0.60.50.90.1-0.3
Vertical activity count, locomotor time 10.10.10.3-0.2-0.20.10.30.3-0.2-0.1-0.50.2
Time >=10cm from walls, locomotor time 21.11.12.1-1.3-1.40.80.91.3-0.7-0.9-0.81.1
Bouts of movement, locomotor time 21.21.31.61.21.1-1.1-1.1-1.21.11.11.1-1.2
Total resting periods, locomotor time 20.60.60.80.90.9-0.7-0.8-0.90.70.70.8-0.8
Rest time, locomotor task time 20.10.10.30.10.50.30.1-0.0-0.5-0.3-0.20.2
Distance moved, locomotor task time 20.10.10.50.20.0-0.2-0.3-0.20.70.60.4-0.0
Vertical activity count, locomotor time 20.00.00.1-0.1-0.4-0.0-0.10.20.4-0.1-0.00.1
Weight adjusted by age2.83.25.5-1.8-2.41.32.21.5-1.7-1.9-1.71.3
Seeking ratio, delayed vs. immediate footshock1.71.92.6-1.5-1.21.51.31.6-1.2-1.2-1.41.5
Locomotion in novel chamber0.10.20.60.3-0.2-0.8-0.2-0.40.20.10.2-0.6
Locomotion in novel chamber post-restriction2.93.54.5-1.7-1.51.72.11.8-2.1-2.0-2.11.9
Progressive ratio0.40.50.70.70.3-0.6-0.8-0.90.70.70.6-0.8
Food seeking constrained by brief footshock0.10.10.20.40.2-0.4-0.3-0.50.20.40.4-0.3
Seeking ratio, punishment vs. effort0.20.30.5-0.6-0.30.40.50.7-0.6-0.5-0.50.7
Run reversals in cocaine runway, females0.10.10.40.30.6-0.3-0.6-0.30.10.20.2-0.3
Run reversals in cocaine runway, males0.80.71.3-0.7-0.80.41.21.0-1.1-0.8-1.00.6
Latency to leave start box in cocaine runway0.10.10.50.20.70.2-0.6-0.10.0-0.00.10.2
Latency to leave start box in cocaine runway, F0.20.20.4-0.20.30.6-0.50.5-0.1-0.4-0.10.7
Latency to leave start box in cocaine runway, M0.10.10.50.30.7-0.10.1-0.3-0.2-0.1-0.1-0.2
Cd content in liver2.02.22.81.51.3-1.5-1.6-1.41.71.61.6-1.2
Co content in liver0.40.40.60.70.6-0.7-0.7-0.80.50.60.5-0.7
Cu content in liver0.10.10.3-0.2-0.50.10.60.2-0.00.1-0.00.0
Fe content in liver1.72.02.61.51.2-1.5-1.6-1.51.21.41.1-1.5
K content in liver1.21.21.7-1.1-0.11.30.91.3-1.1-1.1-1.31.3
Mg content in liver0.20.21.50.11.20.3-0.20.4-0.1-0.1-0.30.4
Mn content in liver0.20.20.4-0.4-0.30.50.60.5-0.1-0.4-0.30.5
Na content in liver0.10.10.20.40.3-0.4-0.3-0.40.30.40.2-0.4
Rb content in liver1.31.72.4-1.4-1.11.41.11.6-0.9-1.2-1.31.5
Se content in liver0.20.30.5-0.40.40.60.40.5-0.7-0.4-0.60.7
Sr content in liver0.10.10.2-0.0-0.4-0.20.3-0.3-0.00.30.3-0.1
Zn content in liver0.10.10.10.30.2-0.3-0.3-0.40.20.30.1-0.3