Hub : Genes

Zdhhc6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000054681 0.07 0.04 7.3e-08 0.05 0.03 0.03 0.04 1.6e-06 1.3e-04 1.5e-04 2.4e-05
2 Adipose alternative polyA ENSRNOT00000087680 0.04 0.03 1.6e-05 0.03 0.01 0.02 0.02 7.0e-04 1.0e-02 1.5e-03 2.8e-03
3 Adipose alternative polyA ENSRNOT00000103424 0.05 0.04 7.9e-05 0.01 0.03 0.03 0.02 1.7e-02 2.3e-04 7.7e-04 1.4e-03
4 Adipose alternative polyA ENSRNOT00000054681 0.08 0.05 8.2e-09 0.06 0.05 0.05 0.06 1.1e-07 1.6e-06 3.1e-06 5.3e-07
5 Adipose alternative polyA ENSRNOT00000103424 0.08 0.05 1.1e-09 0.07 0.06 0.06 0.07 1.7e-08 2.3e-07 5.6e-07 5.4e-08
6 Adipose gene expression ENSRNOG00000036576 0.04 0.04 6.4e-03 0.01 -0 0 0 2.3e-02 5.6e-01 1.8e-01 1.2e-01
7 Adipose isoform ratio ENSRNOT00000054681 0.05 0.04 4.2e-06 0.04 0.02 0.03 0.03 1.6e-05 9.6e-04 2.5e-04 1.2e-04
8 Adipose isoform ratio ENSRNOT00000087680 0.03 0.02 6.6e-04 0.02 0.01 0.01 0.01 5.9e-03 2.4e-02 7.8e-03 8.3e-03
9 Adipose isoform ratio ENSRNOT00000103424 0.05 0.04 3.7e-04 0 0.02 0.02 0.02 1.2e-01 9.0e-04 6.6e-03 5.4e-03
10 BLA mRNA stability ENSRNOG00000036576 0.11 0.07 4.0e-04 0.05 0.05 0.04 0.05 9.8e-04 1.5e-03 4.5e-03 1.3e-03
11 Brain intron excision ratio chr1:254342845:254343415 0.03 0.03 6.3e-03 0.03 0.02 0.03 0.03 2.2e-03 6.8e-03 1.6e-03 1.0e-03
12 Brain mRNA stability ENSRNOG00000036576 0.08 0.05 2.2e-05 0.05 0.04 0.04 0.04 1.8e-05 6.8e-05 1.3e-04 5.1e-05
13 NAcc mRNA stability ENSRNOG00000036576 0.13 0.1 8.9e-06 0.07 0.07 0.06 0.07 9.6e-06 6.4e-06 4.0e-05 6.8e-06
14 PL mRNA stability ENSRNOG00000036576 0.11 0.07 3.8e-06 0.08 0.07 0.07 0.07 1.1e-06 5.5e-06 4.8e-06 4.4e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail4.815.537.64.5-4.5-4.26.1-6.11.64.5-4.4-3.8-1.4-3.8-1.9-1.6-2.0
BMI without tail2.34.711.01.9-1.9-2.73.3-3.31.71.9-1.9-2.6-1.5-1.1-1.8-1.6-1.8
Body weight6.025.258.76.1-6.1-5.17.7-7.71.86.1-5.6-4.6-1.8-5.1-2.1-1.7-2.2
Epididymis fat weight9.522.246.65.2-5.2-5.66.8-6.83.15.2-3.9-5.3-3.0-3.8-2.9-3.1-3.2
Glucose2.13.37.62.5-2.5-1.12.4-2.4-0.32.5-2.4-0.90.2-2.8-0.10.30.0
Heart weight0.71.03.30.2-0.2-1.11.8-1.80.20.2-1.6-1.0-0.8-0.3-0.9-0.5-0.7
Left kidney weight2.36.619.52.7-2.7-0.53.4-3.4-1.82.7-4.4-0.01.2-3.91.51.81.4
Right kidney weight2.36.518.32.9-2.9-1.33.9-3.9-0.82.9-4.3-0.90.5-3.40.51.00.6
Tail length0.41.11.90.4-0.4-1.31.1-1.11.40.4-0.1-1.3-1.40.5-1.3-1.2-1.3
Length with tail1.45.311.53.0-3.0-2.33.4-3.40.93.0-2.5-2.0-1.0-2.3-0.8-0.7-0.9
Length without tail3.47.515.33.7-3.7-2.13.9-3.90.23.7-3.4-1.8-0.2-3.5-0.3-0.1-0.3
Liver weight, left3.86.29.72.9-2.9-3.12.7-2.72.32.9-0.7-3.0-2.4-1.5-2.2-2.2-2.3
Liver weight, right5.99.919.54.4-4.4-3.14.2-4.21.24.4-2.6-2.8-1.4-3.3-1.6-1.2-1.6
Parametrial fat weight6.713.120.93.9-3.9-4.64.5-4.53.23.9-1.6-4.4-3.2-2.4-3.0-3.1-3.0
Retroperitoneal fat weight7.424.556.25.6-5.6-5.67.5-7.52.55.6-4.9-5.1-2.5-5.1-2.3-2.4-2.5
Intraocular pressure3.44.89.11.1-1.1-3.02.6-2.62.41.1-0.8-3.0-2.2-0.2-2.7-2.5-2.7
Extensor digitorum longus weight0.52.13.21.8-1.8-1.71.8-1.81.11.8-0.9-1.6-1.1-0.9-1.4-1.0-1.4
Soleus weight2.88.317.34.2-4.2-1.53.8-3.8-0.34.2-3.6-1.10.4-4.00.00.8-0.1
Tibialis anterior weight0.20.51.60.1-0.1-0.70.1-0.10.80.10.5-0.8-1.00.5-1.3-1.0-1.3
Tibia length0.82.36.01.8-1.8-0.51.9-1.9-0.81.8-2.4-0.30.6-2.40.80.70.8
Number of licking bursts1.31.62.91.1-1.1-1.40.6-0.61.51.10.6-1.5-1.50.3-1.7-1.5-1.7
Food consumed during 24 hour testing period0.10.10.4-0.10.10.4-0.10.1-0.5-0.1-0.30.40.60.4-0.20.4-0.2
Times rat made contact with spout1.21.43.41.9-1.9-0.91.4-1.40.31.9-1.0-0.8-0.2-0.9-0.8-0.2-0.8
Mean time between licks in bursts0.60.92.1-0.30.3-1.00.1-0.11.2-0.30.5-1.0-1.11.1-1.5-1.3-1.5
Mean num. licks in bursts1.01.32.80.3-0.30.80.7-0.7-1.50.3-1.70.91.6-1.31.31.51.3
Std. dev. time between licks in bursts1.51.83.6-0.20.2-1.2-0.40.41.8-0.21.5-1.3-1.81.6-1.9-1.8-1.9
Water consumed over 24 hours0.70.81.71.3-1.30.30.8-0.8-0.81.3-1.20.51.0-0.90.41.00.4
Indifference point 0 sec2.03.37.41.9-1.9-2.22.7-2.71.21.9-1.6-2.0-1.2-1.3-1.2-1.2-1.0
Indifference point AUC2.42.84.51.8-1.8-1.90.9-0.92.01.81.0-2.0-1.70.0-2.1-2.0-2.1
Indifference point function ln k0.71.01.7-0.90.91.3-0.60.6-1.2-0.9-0.31.31.30.11.21.31.2
Indifference point function log k0.71.01.7-0.90.91.3-0.60.6-1.2-0.9-0.31.31.30.11.21.31.2
Delay discounting total patch changes 0 sec2.33.77.42.1-2.1-2.42.7-2.71.52.1-1.3-2.2-1.4-1.2-1.6-1.5-1.4
Delay discounting total patch changes 12 sec2.02.74.51.6-1.6-2.01.4-1.41.81.60.1-2.0-1.50.0-2.1-1.8-2.0
Delay discounting total patch changes 18 sec5.06.69.92.7-2.7-3.12.3-2.32.92.70.1-3.1-2.5-0.3-3.0-2.7-3.0
Delay discounting total patch changes 24 sec4.86.011.31.8-1.8-3.11.7-1.73.41.80.7-3.2-2.70.5-3.2-3.1-3.2
Delay discounting total patch changes 6 sec3.65.58.92.5-2.5-3.02.9-2.92.02.5-1.1-2.9-1.9-1.1-2.2-2.1-2.0
Delay discounting time to switch 0 sec0.91.42.8-1.71.71.3-1.11.1-0.9-1.70.11.20.81.01.10.80.9
Delay discounting water rate 0 sec0.71.12.91.7-1.7-0.91.1-1.10.51.7-0.6-0.8-0.3-1.1-0.9-0.3-0.7
Delay discounting water rate 12 sec0.91.42.01.3-1.3-1.41.4-1.41.11.3-0.3-1.4-1.1-0.6-1.2-1.0-1.1
Delay discounting water rate 18 sec0.30.41.20.8-0.8-0.41.0-1.0-0.10.8-1.0-0.30.0-1.1-0.00.20.0
Delay discounting water rate 24 sec1.62.24.22.1-2.1-1.51.9-1.90.82.1-1.1-1.4-0.4-1.2-1.2-0.7-1.2
Delay discounting water rate 6 sec0.60.82.01.4-1.40.30.5-0.5-0.81.4-0.90.40.8-1.40.20.90.3
Locomotor activity0.50.82.80.7-0.70.11.0-1.0-0.60.7-1.70.21.0-1.41.00.80.8
Locomotor testing distance1.22.05.20.7-0.70.51.3-1.3-1.40.7-2.30.71.6-2.01.91.61.7
Locomotor testing rearing0.40.71.80.5-0.5-0.11.1-1.1-0.60.5-1.40.10.5-1.31.10.61.0
Light reinforcement 10.51.02.1-1.31.30.8-1.41.4-0.1-1.31.10.70.11.20.40.10.3
Light reinforcement 20.91.12.7-1.11.11.3-1.61.6-0.6-1.11.01.20.51.00.80.60.8
Reaction time number correct1.52.23.51.9-1.9-1.71.6-1.61.41.9-0.3-1.6-1.1-0.7-1.5-1.2-1.5
Reaction time mean minus median0.20.20.60.8-0.8-0.50.3-0.30.40.80.0-0.5-0.1-0.6-0.2-0.3-0.3
Reaction time mean minus median AUC0.30.41.60.9-0.9-0.10.6-0.6-0.10.9-0.7-0.00.5-1.30.40.40.3
Reaction time num false alarms0.10.20.50.1-0.1-0.40.2-0.20.70.10.1-0.5-0.50.2-0.7-0.5-0.6
Reaction time num false alarms AUC0.00.00.10.1-0.1-0.10.2-0.20.30.1-0.1-0.1-0.1-0.1-0.3-0.1-0.3
Reaction time trials correct on left1.52.23.51.9-1.9-1.71.6-1.61.41.9-0.3-1.6-1.1-0.7-1.5-1.2-1.5
Reaction time trials on left1.52.23.51.9-1.9-1.71.6-1.61.41.9-0.3-1.6-1.1-0.7-1.6-1.2-1.5
Reaction time mean0.40.61.50.1-0.10.8-0.30.3-0.90.1-0.40.81.2-0.81.11.01.1
Reaction time mean AUC0.50.61.4-0.30.31.0-0.60.6-0.8-0.3-0.11.01.2-0.31.10.91.1
Median of all reaction times0.91.22.8-0.00.01.2-0.40.4-1.4-0.0-0.61.31.7-0.91.51.51.5
Reaction time omissions0.10.10.20.0-0.0-0.40.3-0.30.30.0-0.3-0.4-0.1-0.2-0.2-0.3-0.3
Reaction time false alarm rate0.30.41.0-1.01.00.5-0.70.7-0.2-1.00.30.50.10.60.20.20.3
Reaction time premature initiation rate1.31.84.01.4-1.40.50.9-0.9-1.21.4-1.70.61.7-2.01.31.41.2
Reaction time premature initiations2.02.96.82.6-2.6-0.41.8-1.8-0.52.6-1.9-0.21.1-2.50.50.90.4
Std. dev. reaction times0.40.51.21.1-1.1-0.60.9-0.90.21.1-0.7-0.50.0-1.1-0.0-0.1-0.1
Reaction time trials completed1.52.23.51.9-1.9-1.71.6-1.61.41.9-0.3-1.6-1.1-0.7-1.6-1.2-1.5
Reaction time trials AUC1.62.33.51.9-1.9-1.71.6-1.61.51.9-0.4-1.7-1.2-0.7-1.6-1.2-1.6
Social response proportion2.02.25.41.8-1.8-0.11.7-1.7-1.01.8-2.20.11.1-2.30.61.10.7
Social responses3.54.57.32.4-2.4-2.62.7-2.71.82.4-1.0-2.5-1.6-1.4-1.8-1.7-1.8
Social time1.01.33.71.5-1.5-0.61.6-1.6-0.21.5-1.2-0.40.4-1.90.50.30.5
Conditioned locomotion0.10.10.30.3-0.30.4-0.20.2-0.40.3-0.10.40.4-0.20.20.50.2
Cocaine response after cond. corrected1.61.83.3-1.81.81.5-1.21.2-1.3-1.80.21.51.30.91.31.11.2
Cocaine response after cond. not corrected2.12.34.1-2.02.01.7-1.71.7-1.2-2.00.71.61.21.21.31.11.3
Cocaine response before conditioning0.30.31.4-0.10.10.0-0.80.80.6-0.11.2-0.1-0.50.6-0.4-0.5-0.4
Saline control response0.40.51.0-0.60.61.0-0.80.8-0.9-0.60.11.00.80.30.70.80.6
Condit. Reinf. active minus inactive responses3.84.78.6-1.31.3-1.7-0.50.52.9-1.32.2-1.9-2.72.9-2.9-2.9-2.9
Condit. Reinf. active-inactive response ratio2.93.07.0-1.91.9-0.8-0.90.91.9-1.91.9-1.0-1.72.6-1.8-2.0-1.8
Condit. Reinf. active responses3.75.110.9-0.30.3-2.40.4-0.43.3-0.31.7-2.6-3.12.2-3.2-3.2-3.2
Condit. Reinf. inactive responses1.21.52.70.9-0.9-1.50.9-0.91.60.90.3-1.5-1.60.4-1.5-1.5-1.6
Condit. Reinf. lever presses1.82.45.3-0.20.2-1.6-0.00.02.1-0.21.3-1.8-2.21.5-2.2-2.3-2.1
Condit. Reinf. lever reinforcers received3.44.89.7-0.50.5-2.20.2-0.23.1-0.51.7-2.4-3.02.3-3.0-3.1-3.1
Pavlov. Cond. lever latency2.63.68.0-0.10.12.1-0.00.0-2.4-0.1-1.62.22.8-1.72.72.82.6
Pavlov. Cond. magazine entry latency2.02.33.61.5-1.5-1.91.6-1.61.61.5-0.5-1.9-1.6-0.4-1.7-1.5-1.7
Pavlov. Cond. change in total contacts2.73.87.90.4-0.4-2.40.8-0.82.60.41.0-2.5-2.61.4-2.8-2.8-2.8
Pavlov. Cond. index score2.63.46.71.0-1.0-2.31.1-1.12.21.00.5-2.4-2.40.7-2.6-2.5-2.5
Pavlov. Cond. latency score2.63.36.51.1-1.1-2.31.1-1.12.21.10.5-2.4-2.40.6-2.6-2.4-2.5
Pavlov. Cond. lever contacts1.52.14.50.2-0.2-1.70.4-0.41.80.20.8-1.8-2.01.1-2.1-2.1-2.1
Pavlov. Cond. magazine entry number1.92.44.1-1.51.51.9-1.41.4-1.6-1.50.31.91.60.12.01.62.0
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.20.20.2-0.10.10.2-0.20.40.2-0.0-0.10.40.10.3
Pavlov. Cond. lever-magazine prob. diff.2.22.95.80.9-0.9-2.11.0-1.02.00.90.4-2.2-2.20.6-2.4-2.2-2.3
Pavlov. Cond. response bias2.12.86.10.6-0.6-2.10.8-0.82.10.60.6-2.2-2.31.0-2.5-2.3-2.4
Conditioned reinforcement - actives0.20.20.4-0.60.60.2-0.50.5-0.2-0.60.20.20.30.6-0.1-0.0-0.0
Conditioned reinforcement - inactives0.80.91.40.8-0.8-1.20.8-0.81.10.80.1-1.2-1.0-0.1-1.2-1.1-1.2
Conditioned locomotion0.30.30.60.6-0.60.5-0.80.8-0.70.60.60.50.5-0.40.50.40.5
Intermittent access intake day 1-15 change2.12.13.21.4-1.4-1.81.8-1.81.81.4-0.3-1.7-1.1-0.6-1.3-1.3-1.7
Intermittent access intake escalation2.02.04.31.5-1.5-1.62.1-2.11.21.5-1.1-1.5-0.7-1.2-1.0-0.8-1.1
Intermittent access intake escalation 21.31.22.21.5-1.5-1.11.5-1.50.81.5-0.8-1.0-0.4-1.1-0.7-0.5-0.7
Intermitt. access day 1 inactive lever presses2.32.53.91.7-1.7-2.01.5-1.51.81.70.1-2.0-1.8-0.3-1.6-1.6-1.8
Intermitt. access day 15 inactive lever presses0.30.40.7-0.60.6-0.60.1-0.10.8-0.60.3-0.6-0.60.6-0.6-0.8-0.7
Intermitt. access escalation Index0.40.30.70.8-0.80.20.3-0.3-0.70.8-0.50.20.4-0.80.50.50.4
Intermittent access day 1 total infusions1.11.22.60.8-0.8-1.20.2-0.21.30.81.0-1.2-1.40.7-1.6-1.5-1.5
Intermittent access day 15 total infusions2.22.44.11.4-1.4-1.91.4-1.41.91.40.2-1.9-1.50.0-2.0-1.7-2.0
Intermittent access terminal intake (last 3 days)1.41.52.71.2-1.2-1.40.9-0.91.41.20.5-1.5-1.20.1-1.6-1.4-1.6
Intermittent access total infusions1.71.93.31.4-1.4-1.60.9-0.91.51.40.7-1.6-1.40.2-1.8-1.6-1.7
Intermittent access day 1 locomotion0.10.10.50.0-0.00.3-0.20.2-0.70.0-0.20.40.5-0.20.40.40.6
Intermittent access day 15 total locomotion1.41.52.41.5-1.5-1.61.5-1.51.01.5-0.4-1.5-0.8-0.8-1.0-1.0-1.0
Intermittent access total locomotion0.20.30.60.7-0.70.10.2-0.2-0.60.7-0.30.20.6-0.80.50.40.5
Intermittent access standard deviation4.04.36.62.2-2.2-2.41.3-1.32.62.20.9-2.4-2.4-0.0-2.5-2.3-2.4
Cocaine induced anxiety4.65.39.1-1.61.63.0-2.22.2-2.6-1.60.13.02.6-0.12.92.72.9
Post-drug Anxiety0.70.81.5-0.30.31.2-0.60.6-1.1-0.3-0.31.21.2-0.31.21.21.2
Baseline Anxiety7.17.511.43.0-3.0-3.42.9-2.92.73.0-0.4-3.3-2.7-0.9-2.9-2.6-2.9
Lifetime Intake2.02.23.91.3-1.3-1.81.0-1.01.81.30.7-1.8-1.70.3-2.0-1.8-1.9
Incentive Sensitization - Responses1.41.42.51.2-1.2-1.41.0-1.01.41.20.2-1.4-1.1-0.1-1.6-1.2-1.6
Incentive Sensitization - Breakpoint1.51.52.71.3-1.3-1.41.0-1.01.51.30.3-1.4-1.1-0.1-1.6-1.3-1.6
Progressive ratio test 1 active lever presses0.60.61.20.3-0.3-1.10.8-0.80.80.3-0.0-1.1-1.00.3-0.8-1.1-0.8
Progressive ratio test 1 breakpoint0.50.61.4-0.10.1-0.90.3-0.30.9-0.10.5-1.0-1.10.8-1.0-1.2-0.9
Progressive ratio test 1 inactive lever presses0.91.02.30.5-0.5-1.10.3-0.31.40.50.7-1.1-1.20.5-1.5-1.2-1.4
Progressive ratio test 2 active lever presses1.61.83.01.2-1.2-1.71.5-1.51.31.2-0.1-1.7-1.2-0.2-1.5-1.4-1.4
Progressive ratio test 2 breakpoint1.82.03.21.3-1.3-1.81.5-1.51.61.30.1-1.8-1.3-0.1-1.7-1.6-1.7
Progressive ratio test 2 inactive lever presses1.51.72.90.9-0.9-1.70.9-0.91.70.90.6-1.7-1.70.3-1.6-1.7-1.7
Total sessions with >9 infusions2.02.25.31.9-1.9-1.42.3-2.30.51.9-1.5-1.3-0.4-1.8-0.4-0.4-0.3
Short access day 1 total inactive lever presses1.31.52.61.6-1.6-1.41.4-1.41.01.6-0.3-1.4-1.1-0.8-0.8-0.9-0.9
Short access day 10 total inactive lever presses0.50.50.80.7-0.7-0.90.7-0.70.80.7-0.1-0.8-0.7-0.2-0.8-0.6-0.9
Short access day 1 total infusions0.50.51.00.9-0.9-0.91.0-1.00.60.9-0.2-0.8-0.6-0.7-0.3-0.5-0.4
Short access day 10 total infusions0.60.61.80.2-0.2-0.8-0.10.10.90.20.8-0.8-1.00.9-1.3-1.1-1.1
Short access total infusions1.11.22.10.8-0.8-1.40.7-0.71.40.80.6-1.4-1.40.3-1.5-1.4-1.4
Short access day 1 locomotion0.40.41.00.5-0.5-0.90.4-0.40.70.50.3-0.9-1.0-0.1-0.5-0.9-0.5
Short access day 10 total locomotion1.21.43.20.7-0.70.50.6-0.6-1.40.7-1.50.71.1-1.81.71.31.7
Short access total locomotion0.50.61.30.3-0.30.30.5-0.5-1.00.3-1.10.40.8-1.11.00.81.0
Compulsive drug intake0.80.81.90.6-0.6-0.6-0.40.41.20.61.1-0.7-1.20.6-1.4-1.0-1.3
One hour access (0.3 mA shock)4.95.88.72.4-2.4-2.91.5-1.52.82.41.2-2.9-2.70.0-2.9-2.9-2.9
One hour access (shock baseline)1.01.21.91.3-1.3-1.41.4-1.40.81.3-0.3-1.3-0.7-0.7-0.8-1.0-0.7
Number of responses in last shaping day0.10.10.4-0.30.3-0.20.6-0.6-0.2-0.3-0.7-0.10.3-0.30.40.10.4
Context. condit. distance diff. score0.91.12.2-1.01.01.4-0.70.7-1.4-1.0-0.51.41.50.41.01.31.0
Locomotion velocity, session 11.01.02.9-0.90.90.5-1.71.70.4-0.91.70.3-0.41.4-0.7-0.5-0.7
Locomotion distance, session 10.40.51.1-0.40.41.1-0.80.8-1.0-0.40.01.11.00.30.50.90.5
Locomotion velocity, session 21.82.14.1-0.60.61.9-1.01.0-2.0-0.6-0.62.02.0-0.31.72.01.8
Locomotion distance, session 20.81.22.41.5-1.5-0.91.6-1.60.21.5-1.2-0.8-0.3-1.1-0.6-0.2-0.6
Locomotion velocity, session 30.20.20.7-0.00.00.6-0.10.1-0.6-0.0-0.60.70.80.20.30.80.2
Locomotion distance, session 30.80.92.4-0.30.31.00.2-0.2-1.5-0.3-1.41.11.6-0.40.71.40.6
Stereotopy head waving bouts, day 30.10.10.30.4-0.4-0.40.3-0.30.50.4-0.1-0.4-0.3-0.3-0.5-0.3-0.6
Stereotopy head waving duration, day 30.50.61.9-0.70.70.2-1.11.10.7-0.71.40.0-0.51.1-0.5-0.5-0.5
Locomotion velocity, session 70.10.10.10.3-0.3-0.20.1-0.10.30.30.0-0.2-0.20.2-0.4-0.2-0.4
Locomotion distance, session 70.20.20.60.1-0.10.6-0.20.2-0.80.1-0.30.70.80.10.50.80.5
Stereotopy head waving bouts, day 70.10.10.30.1-0.1-0.40.1-0.10.50.10.2-0.4-0.40.1-0.5-0.5-0.4
Stereotopy head waving duration, day 70.40.51.20.6-0.6-0.90.6-0.61.10.60.2-0.9-0.9-0.0-0.8-0.9-0.8
Locomotion velocity, session 81.01.22.3-0.70.71.5-1.51.5-0.9-0.70.71.51.10.80.91.10.8
Locomotion distance, session 80.50.81.9-0.40.41.2-0.40.4-1.3-0.4-0.61.21.40.20.91.30.8
Degree of sensitization distance0.60.62.5-0.20.2-0.4-0.90.91.0-0.21.6-0.5-1.11.0-0.4-1.0-0.3
Degree of sensitization stereotypy0.20.30.70.2-0.2-0.70.3-0.30.80.20.2-0.7-0.70.2-0.6-0.7-0.6
Condit. Reinf. active minus inactive responses0.60.72.0-1.41.4-0.1-0.40.40.3-1.40.3-0.1-0.31.1-0.8-0.5-0.8
Condit. Reinf. active-inactive response ratio0.80.92.7-1.61.60.3-0.80.80.1-1.60.60.2-0.11.2-0.4-0.3-0.4
Condit. Reinf. active responses0.81.03.0-0.60.6-1.00.5-0.51.0-0.6-0.1-1.1-1.10.8-1.7-1.2-1.7
Condit. Reinf. inactive responses1.31.53.80.6-0.6-1.50.9-0.91.50.6-0.1-1.5-1.40.3-1.9-1.4-2.0
Incentive salience index mean1.01.23.8-1.91.90.3-0.90.90.1-1.90.60.2-0.21.5-0.6-0.4-0.7
Condit. Reinf. lever presses0.60.71.8-1.31.30.2-1.01.00.2-1.30.80.1-0.31.3-0.5-0.4-0.5
Time in familiar zone, hab. session 11.81.73.1-1.21.21.5-0.80.8-1.5-1.2-0.41.51.5-0.21.81.51.8
Time in novel zone, hab. session 12.22.13.51.2-1.2-1.80.9-0.91.81.20.6-1.8-1.90.2-1.9-1.8-1.9
Total zone transitions, hab. session 10.81.12.31.3-1.3-0.71.5-1.5-0.11.3-1.4-0.6-0.0-1.3-0.30.0-0.3
Total locomotion distance, hab. session 10.20.20.50.5-0.5-0.50.3-0.30.20.50.0-0.5-0.50.1-0.7-0.5-0.6
Locomotion velocity, hab. session 10.10.20.50.4-0.4-0.40.2-0.20.10.40.0-0.4-0.40.2-0.7-0.4-0.6
Time in familiar zone, hab. session 23.63.76.91.1-1.1-2.61.9-1.92.41.1-0.1-2.6-2.4-0.6-2.2-2.3-2.2
Time in novel zone, hab. session 22.12.13.9-0.90.91.9-1.11.1-1.9-0.9-0.52.02.00.21.81.91.8
Total zone transitions, hab. session 21.11.44.01.0-1.0-1.22.0-2.00.31.0-1.8-1.1-0.4-1.2-0.6-0.3-0.6
Total locomotion distance, hab. session 20.71.02.51.0-1.0-1.11.6-1.60.31.0-1.3-1.0-0.4-0.8-0.7-0.4-0.6
Locomotion velocity, hab. session 20.40.61.40.9-0.9-0.71.2-1.20.00.9-1.1-0.6-0.2-0.7-0.4-0.2-0.4
Novel to familiar place preference ratio0.20.20.50.1-0.1-0.4-0.10.10.50.10.6-0.5-0.70.2-0.7-0.7-0.7
Novelty place preference0.30.30.60.3-0.3-0.60.0-0.00.60.30.6-0.6-0.80.1-0.7-0.7-0.7
Time in novel zone, NPP test0.80.81.70.6-0.6-1.20.5-0.51.20.60.6-1.2-1.30.1-1.2-1.2-1.2
Total zone transitions, NPP test1.52.24.01.7-1.7-1.72.0-2.00.81.7-1.3-1.6-1.0-1.3-1.3-0.9-1.3
Total locomotion distance, NPP test1.31.83.01.3-1.3-1.61.7-1.70.81.3-1.0-1.5-1.1-0.6-1.5-1.0-1.4
Locomotion velocity, NPP test0.50.71.41.1-1.1-0.81.2-1.20.11.1-1.0-0.7-0.3-0.6-0.8-0.3-0.7
Pavlov. Cond. lever latency0.60.71.30.8-0.8-1.11.0-1.00.90.8-0.1-1.1-0.9-0.5-0.9-0.9-0.9
Pavlov. Cond. magazine entry latency0.40.51.00.8-0.8-0.81.0-1.00.30.8-0.8-0.7-0.4-0.8-0.6-0.3-0.6
Pavlov. Cond. change in total contacts0.20.20.50.2-0.20.40.1-0.1-0.70.2-0.60.50.7-0.50.50.70.4
Pavlov. Cond. index score0.20.20.70.5-0.5-0.10.6-0.6-0.30.5-0.8-0.00.3-0.80.10.30.1
Pavlov. Cond. latency score0.10.20.50.4-0.40.00.4-0.4-0.30.4-0.70.10.3-0.60.20.40.3
Pavlov. Cond. lever contacts0.30.30.6-0.70.70.6-0.80.8-0.4-0.70.40.60.30.50.30.30.3
Pavlov. Cond. magazine entry number0.81.02.3-1.11.10.7-1.51.50.0-1.11.50.6-0.01.40.4-0.10.3
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.10.1-0.40.4-0.40.3-0.1-0.3-0.3-0.20.2-0.3-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.40.5-0.5-0.20.5-0.5-0.10.5-0.6-0.10.1-0.7-0.00.1-0.0
Pavlov. Cond. response bias0.10.10.50.2-0.20.00.4-0.4-0.40.2-0.70.10.3-0.60.10.40.2
Bone: apparent density2.13.44.92.2-2.2-2.11.8-1.81.72.2-0.2-2.1-1.8-0.5-2.0-1.7-2.0
Bone surface0.50.91.81.3-1.3-1.11.1-1.10.61.3-0.5-1.0-0.8-0.5-0.6-0.7-0.6
Bone volume2.44.16.92.6-2.6-2.32.5-2.51.52.6-1.1-2.2-1.6-1.4-1.5-1.4-1.5
Bone: connectivity density0.00.10.40.2-0.20.0-0.30.3-0.10.20.4-0.0-0.20.6-0.2-0.2-0.2
Bone: cortical apparent density4.45.711.4-1.71.72.9-1.31.3-3.4-1.7-1.13.03.2-0.43.03.03.0
Bone: cortical area5.17.712.73.0-3.0-3.43.6-3.62.53.0-1.4-3.2-2.4-1.6-2.3-2.2-2.3
Bone: cortical porosity0.90.91.90.7-0.7-1.00.2-0.21.30.70.7-1.0-1.20.8-1.4-1.2-1.4
Bone: cortical porosity1.51.63.01.0-1.0-1.50.7-0.71.71.00.6-1.5-1.60.6-1.7-1.6-1.7
Bone: cortical thickness2.03.36.92.2-2.2-2.02.6-2.61.12.2-1.6-1.8-1.0-1.5-1.2-0.9-1.2
Bone: cortical thickness1.11.23.01.6-1.6-0.61.5-1.5-0.01.6-1.3-0.50.1-1.7-0.10.2-0.2
Bone: cortical tissue density4.66.011.8-1.81.83.0-1.51.5-3.4-1.8-1.03.13.2-0.43.13.13.1
Bone: elastic displacement0.20.20.4-0.10.1-0.50.2-0.20.5-0.10.2-0.5-0.50.6-0.6-0.6-0.6
Bone: elastic work0.60.82.50.9-0.9-0.31.3-1.3-0.40.9-1.6-0.10.5-1.30.40.50.4
Bone: endosteal estimation1.53.25.02.0-2.0-2.22.2-2.21.72.0-0.8-2.1-1.7-1.1-1.5-1.5-1.5
Bone: endosteal perimeter1.93.86.62.3-2.3-2.32.6-2.61.52.3-1.2-2.2-1.6-1.6-1.3-1.4-1.3
Bone: final force1.22.03.31.8-1.8-1.51.8-1.81.01.8-1.1-1.4-1.0-1.4-1.0-0.8-1.0
Bone: final moment1.72.84.62.1-2.1-1.82.1-2.11.12.1-1.3-1.7-1.1-1.6-1.2-1.0-1.2
Bone: marrow area1.63.45.12.0-2.0-2.32.3-2.31.72.0-0.8-2.2-1.7-1.1-1.5-1.5-1.5
Bone: maximum diameter5.19.313.83.6-3.6-3.73.6-3.62.83.6-1.1-3.6-2.8-1.7-2.5-2.6-2.5
Bone: maximum force0.81.52.51.5-1.5-1.31.6-1.60.81.5-1.0-1.2-0.7-1.1-0.9-0.7-0.9
Bone: maximum moment1.22.13.71.8-1.8-1.61.9-1.91.01.8-1.1-1.5-1.0-1.2-1.2-0.9-1.2
Bone: minimum diameter2.54.68.32.0-2.0-2.82.9-2.92.12.0-1.1-2.7-2.1-1.2-1.7-1.9-1.7
Bone: periosteal estimation4.08.214.03.3-3.3-3.43.7-3.72.53.3-1.6-3.3-2.4-2.0-2.2-2.1-2.2
Bone: periosteal perimeter5.28.714.43.6-3.6-3.43.8-3.82.33.6-1.6-3.2-2.3-2.3-2.1-2.1-2.1
Bone: post-yield work0.60.92.0-0.30.3-0.8-0.20.21.3-0.31.1-0.9-1.20.7-1.4-1.3-1.4
Bone: stiffness0.10.10.20.5-0.5-0.20.4-0.40.20.5-0.4-0.2-0.1-0.2-0.2-0.1-0.3
Bone: tissue strength0.40.41.0-1.01.0-0.0-0.40.40.5-1.00.5-0.1-0.30.9-0.3-0.4-0.3
Bone: trabecular number0.71.22.20.9-0.9-1.30.6-0.61.20.90.4-1.3-1.30.3-1.5-1.3-1.5
Bone: trabecular spacing0.10.20.5-0.70.70.1-0.50.50.1-0.70.40.1-0.10.3-0.0-0.20.0
Bone: trabecular thickness4.95.910.13.2-3.2-2.82.8-2.82.13.2-0.8-2.7-2.1-1.5-1.9-1.9-1.9
Bone: trabecular tissue density0.40.51.30.0-0.00.7-0.20.2-1.10.0-0.40.80.8-0.71.10.91.1
Breakpoint value in progressive ratio session1.51.63.40.6-0.6-1.60.6-0.61.70.60.8-1.7-1.80.6-1.6-1.8-1.6
Distance traveled before self-admin2.93.16.4-1.11.11.9-0.40.4-2.3-1.1-1.52.02.3-1.02.52.32.5
Distance traveled after self-admin2.42.65.20.7-0.71.00.9-0.9-2.10.7-2.11.22.0-2.22.32.02.3
Delta time in closed arm before/after self-admin0.80.81.2-1.01.00.8-0.00.0-1.0-1.0-0.80.91.1-0.81.11.11.1
Delta time in open arm before/after self-admin1.91.83.01.4-1.4-1.60.8-0.81.71.40.8-1.7-1.70.2-1.3-1.7-1.4
Diff in mean of infusions in LGA sessions2.02.25.3-2.32.30.9-1.91.9-0.0-2.31.40.8-0.12.2-0.1-0.1-0.1
Extinction: sum of active levers before priming0.80.81.70.7-0.7-0.8-0.20.21.20.71.3-0.9-1.20.6-1.1-1.2-1.1
Active lever presses in extinction session 60.70.71.31.1-1.1-0.90.8-0.80.71.10.2-0.9-0.7-0.6-0.5-0.7-0.6
Delta distance traveled before/after self-admin1.51.64.12.0-2.0-1.01.6-1.60.22.0-0.9-0.9-0.2-1.7-0.1-0.2-0.1
Delta ambulatory time before/after self-admin2.12.34.72.2-2.2-1.71.6-1.61.12.2-0.2-1.6-1.1-1.1-1.0-1.1-1.0
Time in closed arm before self-admin0.10.10.4-0.30.30.00.3-0.3-0.4-0.3-0.70.10.3-0.10.60.20.6
Time in closed arm after self-admin1.11.24.1-2.02.00.7-0.40.4-0.7-2.0-0.50.70.70.40.80.60.8
Time in open arm before self-admin0.70.72.6-0.40.41.1-1.61.6-0.4-0.41.11.00.50.60.20.60.2
Time in open arm after self-admin1.51.63.51.3-1.3-0.8-0.60.61.61.31.9-1.0-1.50.8-1.5-1.4-1.5
Sum of active levers in priming session hrs 5-60.60.62.1-0.20.20.9-1.51.5-0.1-0.21.40.80.10.70.10.30.1
Time to tail flick, vehicle, before self-admin1.41.53.21.8-1.8-1.21.4-1.40.81.8-0.4-1.1-0.7-1.1-0.7-0.7-0.8
Time to tail flick, vehicle, after self-admin0.60.61.21.1-1.10.7-0.00.0-0.71.1-0.40.80.9-0.90.41.10.4
Time to tail flick, test, before self-admin1.51.53.30.9-0.90.60.9-0.9-1.40.9-1.80.81.4-1.71.41.51.4
Time to tail flick, test, after self-admin1.31.32.51.4-1.4-1.41.6-1.60.71.4-0.8-1.3-0.7-0.8-0.8-0.8-0.7
Delta time to tail flick, vehicle, before/after SA0.20.20.4-0.30.30.6-0.50.5-0.4-0.30.10.60.50.30.30.50.3
Delta time to tail flick, test, before/after SA1.11.01.80.7-0.7-1.30.9-0.91.10.70.1-1.3-1.1-0.0-1.3-1.2-1.2
Ambulatory time before self-admin2.32.45.4-0.70.71.40.3-0.3-2.0-0.7-2.01.51.7-1.42.32.02.3
Ambulatory time after self-admin2.83.16.81.4-1.40.91.0-1.0-2.01.4-2.01.11.9-2.62.32.02.3
Total heroin consumption1.61.93.60.4-0.4-1.91.5-1.51.70.4-0.1-1.9-1.90.3-1.7-1.7-1.7
Area under the delay curve1.41.52.51.1-1.1-1.61.0-1.01.41.10.3-1.6-1.40.2-1.4-1.5-1.4
Delay disc. indifference point, 0s delay1.11.22.81.7-1.7-1.01.3-1.30.71.7-0.5-1.0-0.6-0.8-0.6-0.5-0.6
Delay disc. indifference point, 16s delay0.80.81.70.4-0.4-1.00.1-0.11.20.41.0-1.0-1.20.7-1.1-1.3-1.1
Delay disc. indifference point, 2s delay0.20.20.70.8-0.8-0.20.3-0.3-0.00.8-0.2-0.10.0-0.4-0.10.0-0.1
Delay disc. indifference point, 24s delay2.72.64.51.4-1.4-1.90.8-0.82.01.41.1-2.0-2.10.4-2.0-2.1-2.0
Delay disc. indifference point, 4s delay0.40.40.9-0.20.2-0.60.1-0.10.9-0.20.4-0.7-0.60.9-0.9-0.9-0.9
Delay disc. indifference point, 8s delay3.23.35.61.8-1.8-2.41.9-1.91.81.8-0.1-2.3-1.9-0.3-1.8-2.0-1.8
Delay discount exponential model param1.61.72.8-1.11.11.7-1.11.1-1.5-1.1-0.31.71.4-0.21.51.61.5
Delay discount hyperbolic model param1.01.11.9-0.90.91.4-1.01.0-1.2-0.9-0.21.41.1-0.11.21.31.2
Fecal boli incidents, locomotor time 10.10.10.30.0-0.0-0.3-0.10.10.50.00.5-0.4-0.20.2-0.4-0.5-0.5
Change in fecal boli incidents, locomotor task0.30.31.0-1.01.00.3-0.30.30.1-1.0-0.00.2-0.00.50.20.10.0
Time >=10cm from walls, locomotor time 10.50.51.1-0.60.60.9-1.01.0-0.6-0.60.70.90.70.40.40.60.5
Bouts of movement, locomotor time 13.03.35.51.6-1.6-2.31.4-1.42.21.60.5-2.3-2.20.1-2.1-2.2-2.2
Total resting periods, locomotor time 12.73.04.81.5-1.5-2.21.4-1.42.01.50.5-2.2-2.0-0.1-2.0-2.0-2.1
Rest time, locomotor task time 10.20.20.40.5-0.5-0.30.7-0.70.10.5-0.5-0.30.0-0.60.0-0.0-0.0
Distance moved, locomotor task time 10.00.00.20.3-0.30.10.1-0.1-0.40.3-0.20.1-0.0-0.20.20.20.2
Vertical activity count, locomotor time 12.02.03.4-1.51.51.6-0.80.8-1.6-1.5-0.91.71.60.41.81.61.6
Time >=10cm from walls, locomotor time 20.60.61.00.8-0.8-1.00.9-0.90.70.8-0.0-0.9-0.9-0.7-0.4-0.7-0.5
Bouts of movement, locomotor time 20.50.51.4-0.80.80.7-1.21.2-0.1-0.80.90.70.10.90.10.2-0.0
Total resting periods, locomotor time 20.20.20.7-0.40.40.4-0.80.80.1-0.40.70.3-0.10.7-0.1-0.0-0.2
Rest time, locomotor task time 20.30.41.00.2-0.20.6-0.20.2-1.00.2-0.60.70.8-0.30.80.80.9
Distance moved, locomotor task time 20.81.02.40.2-0.2-1.20.6-0.61.30.20.5-1.3-1.50.5-1.2-1.4-1.3
Vertical activity count, locomotor time 20.20.20.30.3-0.3-0.60.5-0.50.50.3-0.2-0.5-0.5-0.1-0.2-0.4-0.5
Weight adjusted by age2.32.68.61.2-1.2-1.42.9-2.90.01.2-2.6-1.2-0.3-2.1-0.1-0.0-0.1
Seeking ratio, delayed vs. immediate footshock0.10.10.40.7-0.70.2-0.30.3-0.00.70.30.20.2-0.10.00.2-0.0
Locomotion in novel chamber1.01.22.8-0.20.21.00.3-0.3-1.5-0.2-1.51.11.7-0.81.31.51.3
Locomotion in novel chamber post-restriction0.91.11.9-1.11.11.4-1.21.2-0.9-1.10.31.31.40.70.91.00.7
Progressive ratio0.80.92.6-1.31.30.2-1.11.10.2-1.31.10.1-0.51.6-0.5-0.5-0.5
Food seeking constrained by brief footshock1.31.63.4-0.50.5-0.9-0.60.61.5-0.51.6-1.0-1.71.6-1.8-1.6-1.8
Seeking ratio, punishment vs. effort0.30.30.50.7-0.7-0.60.7-0.70.50.7-0.2-0.6-0.4-0.5-0.5-0.3-0.6
Run reversals in cocaine runway, females1.01.02.21.1-1.10.20.8-0.8-1.21.1-1.20.31.2-1.50.80.91.0
Run reversals in cocaine runway, males1.21.12.7-1.61.60.6-1.41.4-0.1-1.61.20.40.31.20.4-0.20.4
Latency to leave start box in cocaine runway0.50.51.2-0.50.51.1-1.11.1-0.4-0.50.51.00.70.30.60.80.6
Latency to leave start box in cocaine runway, F1.41.62.7-1.11.11.6-1.21.2-1.2-1.1-0.01.61.50.11.51.41.6
Latency to leave start box in cocaine runway, M0.40.40.80.5-0.5-0.60.2-0.20.90.50.4-0.6-0.80.1-0.9-0.7-0.9
Cd content in liver2.02.15.1-2.22.20.8-1.81.80.1-2.21.60.7-0.12.10.2-0.20.2
Co content in liver0.70.91.9-0.00.01.1-0.20.2-1.3-0.0-0.61.11.3-0.91.31.41.3
Cu content in liver0.30.31.20.6-0.60.10.5-0.5-0.50.6-0.70.20.5-1.10.40.50.4
Fe content in liver0.10.10.30.3-0.3-0.40.5-0.50.30.3-0.2-0.4-0.30.0-0.3-0.3-0.2
K content in liver0.10.10.50.7-0.7-0.0-0.20.20.10.70.4-0.1-0.2-0.1-0.1-0.1-0.1
Mg content in liver0.80.81.50.9-0.9-0.90.1-0.11.20.90.8-1.0-1.20.2-1.0-1.1-1.1
Mn content in liver0.40.40.7-0.60.60.8-0.70.7-0.7-0.60.10.80.70.40.70.70.6
Na content in liver0.80.82.5-0.70.70.0-1.21.20.7-0.71.6-0.1-0.81.5-0.7-0.8-0.7
Rb content in liver0.81.12.8-0.70.7-0.4-0.90.91.2-0.71.5-0.5-1.11.7-1.1-1.1-1.1
Se content in liver0.40.51.5-0.50.50.6-1.21.2-0.0-0.51.10.50.11.10.20.00.2
Sr content in liver2.11.92.9-1.41.41.7-1.41.4-1.4-1.40.51.71.40.91.51.21.4
Zn content in liver2.22.44.1-1.51.52.0-1.61.6-1.7-1.50.22.01.80.61.51.61.5