Hub : Genes

Als2cl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000033921 0.29 0.15 5.7e-06 0.03 0.03 0.02 0.03 1.9e-04 1.6e-04 1.2e-03 3.6e-04
2 Brain gene expression ENSRNOG00000033921 0.67 0.16 1.6e-11 0.12 0.14 0.12 0.12 4.4e-11 1.5e-12 1.2e-11 5.1e-11
3 Brain intron excision ratio chr8:110867698:110868437 0.14 0.14 1.1e-04 0.05 0.05 0.04 0.04 4.4e-05 2.3e-05 8.3e-05 7.6e-05
4 Liver gene expression ENSRNOG00000033921 0.54 0.16 8.1e-14 0.06 0.13 0.13 0.11 9.4e-08 3.4e-14 4.7e-14 5.3e-12
5 NAcc gene expression ENSRNOG00000033921 0.04 0.04 1.8e-03 0.01 0.02 0.01 0.01 4.8e-02 1.4e-02 2.9e-02 3.2e-02
6 PL isoform ratio ENSRNOT00000046745 0.04 0.04 6.6e-03 0.02 0.02 0.01 0.02 8.1e-03 9.5e-03 3.3e-02 1.3e-02
7 PL intron excision ratio chr8:110867698:110868437 0.05 0.05 6.4e-04 0.04 0.04 0.04 0.04 2.5e-04 6.1e-04 4.5e-04 4.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.61.95.62.40.4-1.5-0.91.11.4-1.0
BMI without tail1.63.46.92.61.0-2.00.62.02.2-1.7
Body weight6.025.536.06.04.1-5.43.25.45.6-5.1
Epididymis fat weight0.20.50.60.70.5-0.60.70.80.7-0.7
Glucose0.20.30.60.80.3-0.60.30.60.6-0.5
Heart weight2.02.83.51.81.3-1.71.41.81.9-1.7
Left kidney weight0.51.44.02.00.1-1.10.21.31.5-0.9
Right kidney weight0.10.41.31.2-0.2-0.5-0.20.60.7-0.4
Tail length6.118.422.04.23.8-4.24.14.74.6-4.5
Length with tail8.431.036.75.64.9-5.55.06.15.9-5.7
Length without tail5.913.014.63.73.4-3.72.93.83.8-3.8
Liver weight, left0.10.10.7-0.30.10.10.90.2-0.0-0.2
Liver weight, right0.91.42.11.40.7-1.11.21.41.3-1.2
Parametrial fat weight0.81.52.01.40.7-1.11.21.41.4-1.2
Retroperitoneal fat weight0.41.32.01.40.7-1.11.11.41.3-0.9
Intraocular pressure1.21.73.60.51.5-1.01.91.21.1-1.4
Extensor digitorum longus weight0.10.50.7-0.6-0.50.6-0.8-0.8-0.70.8
Soleus weight3.610.514.03.72.7-3.42.13.43.6-3.4
Tibialis anterior weight0.00.10.10.40.1-0.3-0.20.20.2-0.1
Tibia length6.117.226.85.23.1-4.42.34.44.7-4.2
Number of licking bursts0.10.10.3-0.5-0.10.3-0.2-0.4-0.40.3
Food consumed during 24 hour testing period1.41.62.11.51.2-1.40.81.31.4-1.3
Times rat made contact with spout0.30.40.50.50.6-0.60.70.60.6-0.6
Mean time between licks in bursts0.81.11.9-0.9-0.70.9-1.4-1.2-1.11.1
Mean num. licks in bursts0.40.50.70.80.5-0.70.60.80.8-0.7
Std. dev. time between licks in bursts2.83.45.0-1.7-1.31.6-2.2-2.1-1.91.9
Water consumed over 24 hours0.00.00.10.1-0.1-0.0-0.4-0.1-0.00.1
Indifference point 0 sec1.11.72.21.21.5-1.41.11.31.2-1.4
Indifference point AUC0.00.00.10.3-0.2-0.10.20.30.1-0.3
Indifference point function ln k0.20.31.80.2-0.3-0.0-1.3-0.4-0.00.5
Indifference point function log k0.20.31.80.2-0.3-0.0-1.3-0.4-0.00.5
Delay discounting total patch changes 0 sec1.32.12.91.31.7-1.51.21.51.3-1.5
Delay discounting total patch changes 12 sec0.70.91.40.80.8-0.81.21.10.9-0.9
Delay discounting total patch changes 18 sec2.93.85.31.52.3-2.01.81.91.7-2.2
Delay discounting total patch changes 24 sec2.63.33.91.91.6-1.91.52.01.9-1.9
Delay discounting total patch changes 6 sec0.10.10.30.20.2-0.20.60.40.2-0.4
Delay discounting time to switch 0 sec0.20.20.5-0.7-0.40.6-0.0-0.5-0.50.5
Delay discounting water rate 0 sec0.30.40.80.70.9-0.80.10.50.5-0.8
Delay discounting water rate 12 sec0.30.50.90.90.5-0.80.20.70.8-0.7
Delay discounting water rate 18 sec0.10.20.50.7-0.2-0.3-0.60.10.2-0.0
Delay discounting water rate 24 sec0.50.70.90.80.7-0.81.01.00.8-0.9
Delay discounting water rate 6 sec0.30.51.01.00.4-0.80.10.70.8-0.7
Locomotor activity5.99.411.83.23.0-3.22.23.23.4-3.1
Locomotor testing distance5.89.612.43.32.9-3.32.13.23.5-3.1
Locomotor testing rearing0.50.71.40.61.2-1.00.60.70.9-0.9
Light reinforcement 10.50.81.41.10.4-0.80.91.11.2-0.8
Light reinforcement 20.30.41.3-0.0-1.10.6-0.6-0.4-0.20.8
Reaction time number correct0.20.30.5-0.7-0.30.5-0.5-0.6-0.70.6
Reaction time mean minus median0.00.10.20.4-0.3-0.1-0.10.20.4-0.1
Reaction time mean minus median AUC0.20.20.40.60.2-0.40.30.50.6-0.5
Reaction time num false alarms0.20.30.6-0.8-0.20.5-0.2-0.6-0.50.5
Reaction time num false alarms AUC0.10.10.3-0.5-0.10.40.2-0.3-0.30.2
Reaction time trials correct on left0.20.30.5-0.7-0.30.5-0.5-0.6-0.70.6
Reaction time trials on left0.30.40.6-0.8-0.30.6-0.5-0.7-0.70.6
Reaction time mean0.00.00.00.00.2-0.20.10.10.2-0.1
Reaction time mean AUC0.00.00.0-0.10.1-0.10.10.00.1-0.0
Median of all reaction times0.00.00.1-0.10.3-0.10.30.10.1-0.1
Reaction time omissions0.40.51.5-1.2-0.30.80.4-0.6-0.70.6
Reaction time false alarm rate0.00.00.1-0.4-0.10.30.2-0.1-0.20.1
Reaction time premature initiation rate1.41.92.81.40.9-1.21.61.61.7-1.2
Reaction time premature initiations0.60.91.40.90.6-0.81.21.11.2-0.7
Std. dev. reaction times0.10.10.30.30.3-0.40.30.40.5-0.4
Reaction time trials completed0.30.40.6-0.8-0.30.6-0.5-0.7-0.70.6
Reaction time trials AUC0.30.40.7-0.8-0.30.6-0.5-0.8-0.80.7
Social response proportion0.30.31.40.20.3-0.21.20.60.5-0.5
Social responses0.20.30.40.70.2-0.50.60.70.6-0.6
Social time0.81.01.9-0.8-1.41.2-0.5-0.8-0.91.1
Conditioned locomotion2.83.44.4-2.1-1.62.0-1.1-1.9-2.01.9
Cocaine response after cond. corrected0.20.20.30.40.5-0.50.60.50.4-0.5
Cocaine response after cond. not corrected1.61.82.11.41.2-1.41.11.41.4-1.4
Cocaine response before conditioning1.11.32.51.60.8-1.30.31.21.4-1.1
Saline control response1.41.82.21.01.5-1.31.51.41.3-1.4
Condit. Reinf. active minus inactive responses2.12.63.71.91.4-1.80.91.71.8-1.6
Condit. Reinf. active-inactive response ratio1.51.52.51.60.9-1.30.71.41.4-1.2
Condit. Reinf. active responses1.72.32.71.61.4-1.61.11.61.6-1.6
Condit. Reinf. inactive responses0.00.00.1-0.20.20.0-0.0-0.1-0.1-0.0
Condit. Reinf. lever presses2.33.14.92.21.4-1.90.91.92.0-1.8
Condit. Reinf. lever reinforcers received2.02.83.41.81.7-1.81.11.71.8-1.7
Pavlov. Cond. lever latency0.60.81.6-1.2-0.71.10.0-0.8-1.00.8
Pavlov. Cond. magazine entry latency0.20.31.30.4-0.4-0.0-1.1-0.3-0.10.3
Pavlov. Cond. change in total contacts2.63.75.42.31.8-2.20.81.92.1-1.9
Pavlov. Cond. index score0.20.30.91.00.2-0.6-0.60.40.5-0.3
Pavlov. Cond. latency score0.20.30.80.90.1-0.6-0.70.30.5-0.2
Pavlov. Cond. lever contacts1.11.52.71.61.0-1.40.31.21.3-1.1
Pavlov. Cond. magazine entry number0.30.41.8-0.00.3-0.11.40.60.4-0.6
Pavlov. Cond. intertrial magazine entries0.40.51.5-1.2-0.10.70.2-0.7-0.80.5
Pavlov. Cond. lever-magazine prob. diff.0.30.31.01.00.1-0.6-0.70.30.5-0.2
Pavlov. Cond. response bias0.30.41.01.00.3-0.7-0.70.30.5-0.3
Conditioned reinforcement - actives0.20.20.9-0.20.3-0.1-0.9-0.5-0.4-0.1
Conditioned reinforcement - inactives0.70.81.1-0.8-0.70.8-0.9-1.0-1.10.8
Conditioned locomotion0.20.30.7-0.4-0.20.3-0.8-0.6-0.70.3
Intermittent access intake day 1-15 change0.30.30.5-0.6-0.30.4-0.7-0.7-0.50.4
Intermittent access intake escalation0.20.20.4-0.4-0.10.3-0.7-0.6-0.40.2
Intermittent access intake escalation 20.10.10.20.30.4-0.40.00.20.3-0.4
Intermitt. access day 1 inactive lever presses0.00.00.00.1-0.10.0-0.2-0.1-0.10.2
Intermitt. access day 15 inactive lever presses0.80.91.1-0.9-1.11.0-0.6-0.9-1.01.0
Intermitt. access escalation Index0.00.00.00.10.0-0.1-0.00.0-0.00.1
Intermittent access day 1 total infusions0.00.00.10.00.1-0.1-0.3-0.1-0.20.1
Intermittent access day 15 total infusions0.10.20.5-0.30.00.1-0.7-0.5-0.50.2
Intermittent access terminal intake (last 3 days)0.10.10.4-0.10.2-0.1-0.6-0.3-0.3-0.0
Intermittent access total infusions0.30.30.9-0.4-0.10.2-0.9-0.6-0.70.3
Intermittent access day 1 locomotion0.10.10.2-0.2-0.20.2-0.4-0.3-0.40.4
Intermittent access day 15 total locomotion0.40.40.5-0.6-0.40.5-0.7-0.7-0.70.5
Intermittent access total locomotion0.91.01.4-0.9-0.70.9-1.2-1.1-1.20.9
Intermittent access standard deviation0.30.40.50.60.7-0.70.20.50.7-0.7
Cocaine induced anxiety0.50.60.8-0.8-0.70.8-0.6-0.8-0.90.7
Post-drug Anxiety0.40.40.6-0.7-0.70.8-0.2-0.6-0.70.7
Baseline Anxiety0.20.20.3-0.4-0.50.5-0.2-0.4-0.30.5
Lifetime Intake0.20.20.7-0.3-0.10.2-0.8-0.6-0.60.3
Incentive Sensitization - Responses1.71.61.9-1.3-1.31.3-1.1-1.4-1.31.3
Incentive Sensitization - Breakpoint1.61.61.8-1.2-1.31.3-1.1-1.3-1.21.3
Progressive ratio test 1 active lever presses0.00.10.10.10.3-0.3-0.3-0.0-0.1-0.3
Progressive ratio test 1 breakpoint0.00.00.1-0.00.2-0.1-0.3-0.1-0.2-0.2
Progressive ratio test 1 inactive lever presses0.30.30.7-0.5-0.30.4-0.7-0.6-0.80.4
Progressive ratio test 2 active lever presses0.60.71.1-0.8-0.60.7-1.0-1.0-0.90.7
Progressive ratio test 2 breakpoint0.50.61.0-0.7-0.50.6-1.0-0.9-0.90.6
Progressive ratio test 2 inactive lever presses1.51.72.8-1.2-0.91.1-1.7-1.5-1.51.2
Total sessions with >9 infusions0.00.00.1-0.10.1-0.0-0.3-0.2-0.1-0.0
Short access day 1 total inactive lever presses2.52.84.2-1.5-1.21.4-2.0-1.9-1.81.6
Short access day 10 total inactive lever presses0.00.10.1-0.1-0.30.30.0-0.1-0.20.3
Short access day 1 total infusions0.70.81.0-0.9-0.80.9-0.8-1.0-1.00.8
Short access day 10 total infusions0.10.10.30.10.3-0.2-0.5-0.1-0.2-0.1
Short access total infusions0.30.40.7-0.5-0.30.4-0.8-0.7-0.80.5
Short access day 1 locomotion0.00.00.1-0.1-0.00.0-0.4-0.2-0.20.1
Short access day 10 total locomotion0.10.10.10.20.4-0.30.10.20.0-0.3
Short access total locomotion0.00.00.10.00.1-0.1-0.3-0.1-0.1-0.1
Compulsive drug intake0.00.00.1-0.1-0.30.30.1-0.1-0.10.3
One hour access (0.3 mA shock)0.10.10.4-0.00.2-0.1-0.6-0.3-0.20.0
One hour access (shock baseline)0.10.10.40.10.4-0.3-0.6-0.2-0.1-0.2
Number of responses in last shaping day0.60.60.9-0.7-0.50.6-0.9-0.8-0.90.7
Context. condit. distance diff. score0.00.00.00.10.0-0.0-0.00.00.1-0.0
Locomotion velocity, session 10.10.10.30.0-0.10.1-0.6-0.2-0.10.2
Locomotion distance, session 11.01.32.91.70.6-1.3-0.21.01.3-1.0
Locomotion velocity, session 20.30.41.1-0.1-0.70.4-1.0-0.6-0.40.6
Locomotion distance, session 20.20.31.40.7-0.2-0.3-1.2-0.10.20.1
Locomotion velocity, session 30.20.20.80.9-0.3-0.3-0.50.30.5-0.2
Locomotion distance, session 31.01.12.7-0.3-1.20.8-1.6-1.0-0.81.1
Stereotopy head waving bouts, day 30.10.10.20.10.5-0.30.30.20.2-0.3
Stereotopy head waving duration, day 30.40.40.90.20.9-0.60.90.60.5-0.7
Locomotion velocity, session 70.30.30.40.60.6-0.60.40.60.6-0.6
Locomotion distance, session 70.40.50.8-0.6-0.60.7-0.9-0.8-0.70.8
Stereotopy head waving bouts, day 70.10.20.3-0.4-0.50.50.1-0.3-0.40.4
Stereotopy head waving duration, day 70.10.10.30.40.1-0.30.50.50.4-0.4
Locomotion velocity, session 80.40.51.61.30.1-0.7-0.60.50.8-0.5
Locomotion distance, session 80.40.62.01.40.1-0.8-0.70.60.9-0.5
Degree of sensitization distance1.31.32.20.71.3-1.01.51.21.0-1.2
Degree of sensitization stereotypy0.10.10.2-0.3-0.50.40.5-0.0-0.20.2
Condit. Reinf. active minus inactive responses0.20.20.6-0.10.6-0.20.80.30.2-0.4
Condit. Reinf. active-inactive response ratio0.30.41.00.00.8-0.41.00.50.4-0.6
Condit. Reinf. active responses0.10.10.2-0.5-0.20.40.4-0.2-0.20.1
Condit. Reinf. inactive responses0.80.91.6-0.8-1.31.1-0.7-0.9-0.91.0
Incentive salience index mean0.00.00.1-0.3-0.10.2-0.2-0.2-0.20.2
Condit. Reinf. lever presses1.31.72.7-1.0-1.21.1-1.6-1.4-1.21.3
Time in familiar zone, hab. session 11.01.02.2-1.5-0.31.0-0.3-1.1-1.20.9
Time in novel zone, hab. session 10.30.30.60.80.1-0.50.50.70.7-0.5
Total zone transitions, hab. session 10.60.92.41.50.3-1.0-0.20.91.1-0.8
Total locomotion distance, hab. session 10.20.30.80.90.1-0.5-0.00.60.6-0.4
Locomotion velocity, hab. session 10.20.30.90.90.2-0.60.00.60.7-0.4
Time in familiar zone, hab. session 20.30.30.4-0.6-0.10.4-0.7-0.7-0.60.5
Time in novel zone, hab. session 20.00.00.10.00.2-0.10.30.20.1-0.2
Total zone transitions, hab. session 20.30.41.11.1-0.2-0.5-0.90.30.5-0.1
Total locomotion distance, hab. session 20.20.31.01.00.1-0.6-0.20.50.7-0.4
Locomotion velocity, hab. session 20.20.20.70.9-0.1-0.4-0.20.40.5-0.3
Novel to familiar place preference ratio0.80.91.01.00.9-1.00.61.00.9-0.9
Novelty place preference0.80.80.90.90.9-1.00.70.90.9-0.9
Time in novel zone, NPP test1.01.11.31.01.1-1.10.91.11.0-1.1
Total zone transitions, NPP test2.43.48.12.90.9-2.0-0.11.82.2-1.6
Total locomotion distance, NPP test0.81.22.61.60.5-1.20.21.11.3-1.0
Locomotion velocity, NPP test0.91.33.01.70.5-1.20.21.21.3-1.0
Pavlov. Cond. lever latency4.86.18.22.02.5-2.32.92.72.4-2.6
Pavlov. Cond. magazine entry latency5.67.38.8-2.5-2.42.6-2.8-3.0-2.72.8
Pavlov. Cond. change in total contacts1.31.41.9-1.4-0.71.1-1.1-1.4-1.31.2
Pavlov. Cond. index score5.67.28.7-2.5-2.42.5-2.8-3.0-2.72.8
Pavlov. Cond. latency score5.57.18.5-2.4-2.42.5-2.9-2.9-2.72.8
Pavlov. Cond. lever contacts2.83.35.1-1.4-1.81.6-2.3-2.0-1.71.9
Pavlov. Cond. magazine entry number6.48.09.82.82.4-2.72.83.12.9-2.9
Pavlov. Cond. intertrial magazine entries0.40.50.60.60.7-0.70.80.70.7-0.8
Pavlov. Cond. lever-magazine prob. diff.4.96.27.6-2.3-2.22.3-2.7-2.8-2.52.6
Pavlov. Cond. response bias6.17.59.1-2.5-2.52.6-2.9-3.0-2.82.8
Bone: apparent density0.00.00.10.30.1-0.20.10.20.2-0.2
Bone surface0.10.10.40.1-0.50.2-0.6-0.3-0.10.3
Bone volume0.00.10.20.2-0.30.0-0.4-0.10.00.1
Bone: connectivity density0.20.30.6-0.8-0.50.7-0.1-0.6-0.60.5
Bone: cortical apparent density0.30.40.6-0.8-0.70.8-0.1-0.6-0.70.6
Bone: cortical area0.10.10.2-0.4-0.20.3-0.4-0.4-0.40.3
Bone: cortical porosity0.10.10.4-0.60.10.30.5-0.2-0.40.1
Bone: cortical porosity0.20.20.7-0.80.00.40.3-0.4-0.60.3
Bone: cortical thickness0.10.10.20.40.3-0.40.30.40.4-0.4
Bone: cortical thickness0.00.00.00.10.1-0.10.00.10.1-0.1
Bone: cortical tissue density0.30.40.7-0.8-0.70.8-0.1-0.6-0.70.7
Bone: elastic displacement0.10.10.20.20.4-0.30.20.20.2-0.3
Bone: elastic work0.60.71.41.20.7-1.00.10.81.0-0.8
Bone: endosteal estimation0.10.30.40.30.7-0.50.50.50.4-0.5
Bone: endosteal perimeter1.02.02.4-1.4-1.21.3-1.5-1.6-1.51.5
Bone: final force0.71.11.41.20.9-1.10.81.21.2-1.1
Bone: final moment0.91.62.01.41.0-1.30.91.31.4-1.3
Bone: marrow area0.10.30.40.40.7-0.60.50.50.5-0.6
Bone: maximum diameter0.30.60.8-0.7-0.60.7-0.9-0.9-0.80.8
Bone: maximum force0.61.11.21.01.0-1.10.91.11.1-1.1
Bone: maximum moment0.71.31.51.11.1-1.20.91.21.2-1.2
Bone: minimum diameter0.30.50.8-0.5-0.60.6-0.9-0.8-0.70.7
Bone: periosteal estimation0.00.10.10.20.3-0.30.00.20.2-0.2
Bone: periosteal perimeter1.01.62.0-1.3-1.01.2-1.3-1.4-1.41.3
Bone: post-yield work0.00.00.10.30.1-0.20.00.20.2-0.2
Bone: stiffness0.10.20.40.20.4-0.30.70.50.4-0.5
Bone: tissue strength3.03.03.31.71.7-1.81.41.81.8-1.8
Bone: trabecular number0.50.81.1-0.7-0.90.8-1.0-0.9-0.80.9
Bone: trabecular spacing1.11.42.01.01.0-1.11.41.31.2-1.2
Bone: trabecular thickness0.00.10.20.4-0.2-0.1-0.30.10.2-0.0
Bone: trabecular tissue density0.20.20.30.60.2-0.40.50.60.5-0.5
Breakpoint value in progressive ratio session0.00.00.10.10.1-0.20.40.20.0-0.3
Distance traveled before self-admin0.00.10.20.20.3-0.20.00.10.1-0.4
Distance traveled after self-admin0.10.10.2-0.4-0.30.4-0.4-0.4-0.30.4
Delta time in closed arm before/after self-admin0.10.10.1-0.3-0.30.3-0.4-0.4-0.30.3
Delta time in open arm before/after self-admin0.30.30.30.50.5-0.50.50.60.6-0.4
Diff in mean of infusions in LGA sessions0.00.00.0-0.1-0.20.2-0.0-0.1-0.10.2
Extinction: sum of active levers before priming0.00.00.20.10.3-0.30.10.20.0-0.4
Active lever presses in extinction session 60.30.30.80.50.5-0.60.50.60.4-0.9
Delta distance traveled before/after self-admin0.20.30.5-0.4-0.60.5-0.4-0.5-0.30.7
Delta ambulatory time before/after self-admin0.20.20.40.50.2-0.40.50.50.6-0.1
Time in closed arm before self-admin1.92.23.11.41.7-1.61.11.51.3-1.8
Time in closed arm after self-admin0.10.10.10.20.3-0.30.10.10.0-0.4
Time in open arm before self-admin1.41.51.9-1.1-1.41.3-0.9-1.2-1.21.4
Time in open arm after self-admin0.20.20.2-0.4-0.40.4-0.3-0.4-0.50.5
Sum of active levers in priming session hrs 5-60.30.30.50.50.4-0.50.70.70.4-0.7
Time to tail flick, vehicle, before self-admin1.81.82.61.21.3-1.31.31.41.2-1.6
Time to tail flick, vehicle, after self-admin0.40.40.50.70.5-0.60.60.70.5-0.5
Time to tail flick, test, before self-admin0.10.10.4-0.1-0.60.30.40.1-0.10.3
Time to tail flick, test, after self-admin0.10.10.3-0.3-0.20.3-0.4-0.4-0.60.2
Delta time to tail flick, vehicle, before/after SA0.50.50.9-0.6-0.70.7-0.7-0.7-0.70.9
Delta time to tail flick, test, before/after SA0.20.10.5-0.20.20.1-0.7-0.4-0.50.0
Ambulatory time before self-admin0.00.00.1-0.10.10.0-0.2-0.2-0.2-0.2
Ambulatory time after self-admin0.00.00.0-0.1-0.10.2-0.0-0.1-0.10.1
Total heroin consumption1.01.21.51.10.9-1.11.01.21.1-1.1
Area under the delay curve2.12.22.5-1.5-1.51.6-1.2-1.5-1.61.6
Delay disc. indifference point, 0s delay0.00.00.1-0.1-0.00.0-0.3-0.2-0.10.0
Delay disc. indifference point, 16s delay1.01.01.2-1.0-1.01.0-0.9-1.1-1.11.1
Delay disc. indifference point, 2s delay0.30.30.4-0.5-0.60.6-0.5-0.6-0.60.6
Delay disc. indifference point, 24s delay0.90.81.0-0.9-0.91.0-0.7-0.9-1.01.0
Delay disc. indifference point, 4s delay2.12.22.5-1.5-1.51.6-1.2-1.6-1.51.6
Delay disc. indifference point, 8s delay2.02.12.4-1.4-1.41.5-1.1-1.5-1.51.5
Delay discount exponential model param2.52.62.91.61.6-1.71.31.71.7-1.7
Delay discount hyperbolic model param2.42.62.91.61.6-1.71.31.71.7-1.7
Fecal boli incidents, locomotor time 10.40.40.50.70.6-0.70.40.70.7-0.7
Change in fecal boli incidents, locomotor task0.00.00.10.10.2-0.10.20.10.1-0.3
Time >=10cm from walls, locomotor time 10.20.20.4-0.5-0.40.5-0.0-0.4-0.40.6
Bouts of movement, locomotor time 10.00.00.10.00.1-0.10.20.10.0-0.2
Total resting periods, locomotor time 10.00.00.10.00.2-0.10.20.10.0-0.3
Rest time, locomotor task time 10.40.50.9-0.8-0.50.7-0.6-0.8-1.00.4
Distance moved, locomotor task time 11.41.52.01.31.0-1.31.01.31.4-1.1
Vertical activity count, locomotor time 10.50.60.80.80.6-0.70.80.90.9-0.5
Time >=10cm from walls, locomotor time 21.31.41.81.21.0-1.21.01.31.4-1.1
Bouts of movement, locomotor time 20.10.10.20.40.2-0.3-0.30.10.4-0.3
Total resting periods, locomotor time 20.00.00.20.1-0.0-0.0-0.5-0.10.1-0.1
Rest time, locomotor task time 20.00.00.0-0.10.10.1-0.1-0.1-0.2-0.2
Distance moved, locomotor task time 20.60.61.00.90.6-0.80.91.00.9-0.5
Vertical activity count, locomotor time 20.00.00.00.2-0.0-0.10.20.20.10.2
Weight adjusted by age0.30.30.30.50.5-0.60.40.50.6-0.6
Seeking ratio, delayed vs. immediate footshock2.22.53.5-1.6-1.21.5-1.5-1.7-1.91.5
Locomotion in novel chamber0.10.10.3-0.30.00.2-0.6-0.5-0.40.2
Locomotion in novel chamber post-restriction0.81.01.41.01.0-1.00.71.01.0-1.2
Progressive ratio3.64.25.22.02.2-2.21.52.12.0-2.3
Food seeking constrained by brief footshock0.60.71.2-0.7-0.70.7-1.1-1.0-0.90.9
Seeking ratio, punishment vs. effort5.26.47.6-2.4-2.52.5-2.3-2.7-2.52.7
Run reversals in cocaine runway, females1.91.92.4-1.4-1.51.5-0.9-1.4-1.41.5
Run reversals in cocaine runway, males0.30.30.60.60.3-0.40.70.70.8-0.3
Latency to leave start box in cocaine runway0.20.20.40.50.4-0.50.50.50.6-0.3
Latency to leave start box in cocaine runway, F1.21.31.61.21.1-1.20.91.21.3-1.2
Latency to leave start box in cocaine runway, M0.50.50.6-0.6-0.80.8-0.4-0.6-0.60.8
Cd content in liver2.72.94.71.02.2-1.62.01.61.5-1.8
Co content in liver0.10.10.20.10.4-0.30.10.10.2-0.3
Cu content in liver3.94.85.32.12.3-2.31.82.32.2-2.3
Fe content in liver2.02.44.80.52.0-1.32.21.41.2-1.6
K content in liver0.60.61.61.30.2-0.80.10.81.0-0.7
Mg content in liver0.20.20.80.7-0.4-0.2-0.90.00.30.1
Mn content in liver0.70.92.11.40.4-1.0-0.10.91.1-0.8
Na content in liver0.40.41.40.00.8-0.41.20.60.4-0.6
Rb content in liver1.82.26.1-0.12.0-1.02.51.20.9-1.6
Se content in liver0.00.10.30.3-0.50.1-0.00.10.00.2
Sr content in liver0.30.31.00.9-0.5-0.2-1.00.10.30.1
Zn content in liver4.44.96.12.52.1-2.41.32.32.4-2.3