Mlh1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000033809 0.74 0.08 0.0e+00 0.64 0.65 0.66 0.65 5.8e-92 4.0e-96 6.4e-97 1.4e-95
2 Adipose intron excision ratio chr8:111218688:111219036 0.03 0.02 2.2e-04 0.03 0.03 0.01 0.03 5.1e-04 3.0e-04 1.0e-02 8.4e-04
3 Adipose mRNA stability ENSRNOG00000033809 0.06 0.04 3.6e-03 0.02 0.01 0.02 0.01 2.8e-03 3.6e-02 1.6e-03 1.6e-02
4 BLA gene expression ENSRNOG00000033809 0.46 0.14 0.0e+00 0.46 0.49 0.48 0.48 3.1e-27 1.4e-29 7.1e-29 7.5e-29
5 BLA intron excision ratio chr8:111231159:111233433 0.62 0.15 3.7e-03 0.03 0 0.04 0.02 9.0e-03 2.1e-01 2.1e-03 2.7e-02
6 Brain gene expression ENSRNOG00000033809 0.49 0.12 0.0e+00 0.64 0.65 0.66 0.66 1.1e-76 1.1e-79 2.7e-80 7.5e-81
7 Eye gene expression ENSRNOG00000033809 0.49 0.25 6.1e-05 0.1 0.2 0.07 0.14 1.3e-02 4.5e-04 3.1e-02 4.2e-03
8 IL gene expression ENSRNOG00000033809 0.53 0.14 2.1e-13 0.35 0.38 0.36 0.36 3.6e-09 4.0e-10 2.2e-09 1.4e-09
9 LHb gene expression ENSRNOG00000033809 0.69 0.12 0.0e+00 0.38 0.42 0.38 0.41 4.6e-10 3.1e-11 6.7e-10 9.9e-11
10 Liver alternative TSS ENSRNOT00000097589 0.1 0.11 9.1e-03 0.01 0.01 0.01 0.01 5.5e-02 5.0e-02 6.7e-02 1.9e-02
11 Liver gene expression ENSRNOG00000033809 0.57 0.1 0.0e+00 0.6 0.61 0.61 0.61 5.3e-84 8.0e-85 1.9e-85 5.9e-86
12 Liver mRNA stability ENSRNOG00000033809 0.03 0.02 2.3e-03 0.01 0.01 0 0.01 1.7e-02 1.2e-02 2.7e-01 4.2e-02
13 NAcc gene expression ENSRNOG00000033809 0.67 0.12 0.0e+00 0.49 0.49 0.56 0.55 1.2e-41 2.9e-41 2.2e-49 1.1e-48
14 NAcc mRNA stability ENSRNOG00000033809 0.49 0.15 2.7e-04 0.02 0.05 0.03 0.04 2.0e-02 7.7e-05 2.7e-03 3.8e-04
15 OFC gene expression ENSRNOG00000033809 0.65 0.17 4.3e-15 0.4 0.33 0.41 0.42 1.6e-10 1.1e-08 9.0e-11 4.3e-11
16 PL alternative TSS ENSRNOT00000064581 0.04 0.03 5.1e-03 0.02 0.03 0.01 0.02 1.4e-02 3.0e-03 2.9e-02 1.7e-02
17 PL alternative TSS ENSRNOT00000081718 0.07 0.05 3.2e-05 0.05 0.06 0.06 0.06 7.7e-05 1.2e-05 1.3e-05 5.1e-05
18 PL alternative TSS ENSRNOT00000097589 0.03 0.03 4.7e-03 0.03 0.03 0.03 0.03 1.6e-03 2.8e-03 3.5e-03 2.0e-03
19 PL alternative TSS ENSRNOT00000064581 0.04 0.03 1.5e-03 0.03 0.04 0.02 0.03 1.9e-03 8.6e-04 9.1e-03 1.2e-03
20 PL gene expression ENSRNOG00000033809 0.5 0.11 0.0e+00 0.57 0.58 0.59 0.59 1.3e-51 6.3e-54 3.4e-55 1.2e-55

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
BMI with tail0.82.67.91.5-1.72.81.7-2.61.5-0.11.71.40.81.51.61.30.31.11.5-1.71.71.61.5
BMI without tail1.73.67.32.0-1.92.72.0-2.12.01.11.91.91.42.12.01.6-0.91.81.9-1.92.22.11.8
Body weight6.828.934.35.6-5.65.55.9-4.55.64.65.85.75.05.65.85.51.15.25.7-5.85.65.75.6
Epididymis fat weight0.40.83.70.9-0.80.91.0-1.90.9-0.20.70.81.00.80.81.10.40.70.8-0.70.90.81.0
Glucose0.20.32.50.5-0.1-0.40.2-0.00.60.70.00.50.30.70.30.1-1.60.50.20.10.60.40.5
Heart weight2.53.65.32.0-2.21.72.0-1.41.92.02.31.91.32.12.11.71.21.72.1-2.31.62.01.8
Left kidney weight0.41.25.91.1-0.5-0.30.8-1.11.51.30.51.00.71.60.80.5-2.40.90.7-0.41.21.01.3
Right kidney weight0.20.44.40.5-0.1-0.70.3-1.10.70.3-0.00.40.00.70.20.0-2.10.40.10.10.60.40.7
Tail length5.617.025.14.4-4.03.04.2-2.24.45.04.24.64.34.44.44.2-0.34.54.4-4.14.44.44.4
Length with tail8.330.339.95.9-5.54.05.8-3.55.96.35.76.05.75.95.95.70.45.85.9-5.65.75.95.9
Length without tail6.514.117.73.9-3.82.64.1-2.73.93.83.94.04.13.84.04.21.63.84.0-3.93.83.94.2
Liver weight, left0.20.31.90.00.4-1.3-0.3-0.50.10.0-0.6-0.10.1-0.0-0.3-0.1-1.40.1-0.40.7-0.1-0.20.2
Liver weight, right0.81.32.21.3-0.90.41.2-1.41.40.90.91.21.31.41.11.3-0.81.31.0-0.81.31.21.5
Parametrial fat weight0.71.45.21.3-1.02.31.1-0.81.30.70.91.21.01.31.10.8-1.41.21.0-0.81.21.21.1
Retroperitoneal fat weight0.41.52.61.4-1.10.81.4-1.51.50.71.01.31.61.41.21.4-0.01.11.1-1.01.11.21.6
Intraocular pressure0.81.24.41.2-1.20.71.0-2.11.20.80.91.10.81.01.01.1-0.51.31.0-0.81.01.11.2
Extensor digitorum longus weight0.10.41.4-0.70.3-0.3-0.60.2-0.7-1.0-0.3-0.7-1.2-0.7-0.5-0.80.5-0.8-0.50.3-0.7-0.5-0.7
Soleus weight3.610.412.53.4-3.42.33.5-2.33.53.23.43.52.93.53.53.30.13.33.5-3.43.53.53.5
Tibialis anterior weight0.00.10.30.3-0.50.00.4-0.40.3-0.10.60.3-0.10.20.40.30.60.20.4-0.60.20.40.3
Tibia length6.518.322.44.5-4.13.44.7-3.14.64.34.44.64.74.74.54.70.54.24.5-4.34.74.54.6
Number of licking bursts0.10.20.8-0.2-0.10.8-0.1-0.1-0.4-0.80.1-0.3-0.4-0.4-0.1-0.10.9-0.3-0.1-0.1-0.4-0.2-0.4
Food consumed during 24 hour testing period1.72.04.51.5-1.62.11.5-1.91.40.31.51.40.81.41.51.3-0.11.31.4-1.41.41.51.3
Times rat made contact with spout0.30.41.20.7-0.80.90.6-1.10.60.10.70.60.10.60.70.5-0.30.60.6-0.60.60.70.5
Mean time between licks in bursts0.71.02.1-1.10.8-0.4-1.00.8-1.1-1.1-0.8-1.1-1.5-1.1-0.9-1.20.2-1.1-0.90.7-1.1-1.0-1.2
Mean num. licks in bursts0.30.41.50.7-0.4-0.20.5-0.70.80.70.30.70.40.80.50.4-1.20.70.5-0.20.80.60.7
Std. dev. time between licks in bursts2.22.77.2-1.71.20.1-1.50.5-1.9-2.7-1.2-1.8-2.0-1.9-1.5-1.61.1-1.9-1.51.1-1.9-1.6-1.9
Water consumed over 24 hours0.20.21.60.1-0.51.30.3-0.80.0-0.90.50.0-0.3-0.00.30.10.7-0.10.2-0.5-0.00.2-0.1
Indifference point 0 sec0.91.43.21.3-0.90.21.2-0.91.41.20.91.31.81.41.11.4-0.21.41.1-0.81.21.21.5
Indifference point AUC0.30.42.10.00.6-1.5-0.11.00.11.3-0.40.20.90.2-0.20.1-0.50.2-0.10.40.4-0.10.3
Indifference point function ln k0.10.21.2-0.2-0.11.1-0.1-0.6-0.1-1.10.1-0.3-0.6-0.1-0.1-0.3-0.2-0.5-0.1-0.1-0.2-0.1-0.4
Indifference point function log k0.10.21.2-0.2-0.11.1-0.1-0.6-0.1-1.10.1-0.3-0.6-0.1-0.1-0.3-0.2-0.5-0.1-0.1-0.2-0.1-0.4
Delay discounting total patch changes 0 sec1.21.93.41.5-1.20.61.5-1.21.51.11.21.51.91.51.31.60.21.51.4-1.21.41.41.6
Delay discounting total patch changes 12 sec0.60.72.40.9-0.50.30.80.40.91.50.71.01.31.00.80.8-0.11.00.8-0.70.90.80.9
Delay discounting total patch changes 18 sec2.33.06.91.8-1.30.61.7-0.31.82.41.42.02.61.71.62.00.02.21.7-1.42.01.72.0
Delay discounting total patch changes 24 sec2.53.24.11.9-1.71.21.9-0.81.92.01.82.02.02.01.91.90.21.91.9-1.82.01.91.8
Delay discounting total patch changes 6 sec0.10.21.30.20.3-1.10.0-0.30.30.6-0.30.20.60.4-0.10.2-0.80.3-0.10.40.20.00.4
Delay discounting time to switch 0 sec0.20.31.1-0.40.10.9-0.50.1-0.5-1.0-0.2-0.5-1.0-0.5-0.4-0.7-0.0-0.5-0.40.2-0.7-0.4-0.8
Delay discounting water rate 0 sec0.40.61.10.7-0.60.10.8-0.00.61.10.80.71.10.60.70.91.00.80.8-0.80.70.70.8
Delay discounting water rate 12 sec0.40.51.00.8-0.80.70.8-1.00.80.70.80.70.40.90.80.7-0.10.60.7-0.80.80.80.7
Delay discounting water rate 18 sec0.60.85.70.5-0.91.20.9-2.40.4-1.50.70.30.30.40.60.91.5-0.00.5-0.80.30.50.6
Delay discounting water rate 24 sec0.81.12.91.0-1.10.61.2-1.71.00.51.01.01.20.91.01.30.80.81.0-1.00.91.01.1
Delay discounting water rate 6 sec0.40.62.10.6-0.40.10.70.40.81.40.60.71.20.90.60.80.40.70.7-0.60.90.60.7
Locomotor activity5.79.110.83.2-3.23.33.1-1.93.23.13.23.32.83.03.33.0-0.33.13.3-3.23.23.33.1
Locomotor testing distance5.59.214.93.2-3.23.93.0-2.33.32.83.13.22.53.13.22.8-1.03.13.2-3.13.23.32.9
Locomotor testing rearing0.40.61.10.9-1.00.90.7-1.10.80.70.80.80.20.70.80.6-0.40.90.8-0.80.70.90.7
Light reinforcement 10.50.93.01.0-0.91.41.0-1.71.00.40.80.90.81.00.90.9-0.60.70.8-0.80.90.90.9
Light reinforcement 20.50.62.0-0.50.8-0.9-0.6-1.3-0.2-1.0-0.9-0.6-0.6-0.2-0.8-0.5-1.4-0.8-0.81.0-0.5-0.6-0.3
Reaction time number correct0.30.51.7-0.50.30.5-0.7-0.0-0.6-1.3-0.5-0.7-1.1-0.8-0.5-0.8-0.7-0.6-0.60.6-0.7-0.5-0.8
Reaction time mean minus median0.10.11.60.0-0.00.3-0.1-0.50.20.0-0.10.0-0.50.10.0-0.3-1.30.1-0.10.10.20.10.1
Reaction time mean minus median AUC0.30.32.50.4-0.30.10.2-1.60.50.00.10.3-0.40.40.30.0-1.40.40.2-0.10.50.40.5
Reaction time num false alarms0.40.61.8-0.60.7-1.3-0.80.8-0.6-0.2-0.8-0.6-0.7-0.8-0.7-0.8-0.8-0.5-0.70.8-0.9-0.7-0.6
Reaction time num false alarms AUC0.20.31.2-0.40.5-1.0-0.60.4-0.3-0.1-0.6-0.4-0.5-0.4-0.5-0.5-1.1-0.3-0.50.7-0.7-0.4-0.3
Reaction time trials correct on left0.30.51.7-0.50.30.5-0.7-0.0-0.6-1.3-0.5-0.7-1.1-0.8-0.5-0.8-0.7-0.6-0.60.6-0.7-0.5-0.8
Reaction time trials on left0.40.51.8-0.50.30.5-0.7-0.0-0.7-1.4-0.6-0.7-1.2-0.8-0.6-0.8-0.8-0.6-0.70.6-0.8-0.6-0.9
Reaction time mean0.00.00.30.1-0.10.50.0-0.40.20.00.10.1-0.10.00.1-0.1-0.50.10.1-0.10.20.10.0
Reaction time mean AUC0.10.10.70.00.00.3-0.1-0.80.1-0.4-0.2-0.0-0.3-0.1-0.1-0.2-0.80.1-0.10.20.1-0.0-0.0
Median of all reaction times0.00.00.20.1-0.10.40.0-0.30.10.10.10.10.10.10.1-0.0-0.20.10.1-0.10.10.10.0
Reaction time omissions0.50.71.6-0.70.50.0-0.90.1-0.8-1.2-0.8-0.8-1.2-0.9-0.7-1.0-0.7-0.6-0.80.8-0.9-0.7-0.9
Reaction time false alarm rate0.10.21.9-0.30.4-1.4-0.30.4-0.20.3-0.4-0.2-0.0-0.2-0.4-0.2-0.3-0.2-0.30.5-0.4-0.3-0.1
Reaction time premature initiation rate1.41.94.01.4-1.22.01.3-1.11.61.51.21.41.51.71.31.3-0.71.21.4-1.21.21.41.1
Reaction time premature initiations0.71.04.51.0-0.92.10.8-1.01.10.70.90.90.81.10.90.7-1.00.80.9-0.80.61.00.5
Std. dev. reaction times0.10.22.20.2-0.10.10.0-0.60.40.3-0.00.2-0.30.20.1-0.1-1.50.30.10.10.40.20.3
Reaction time trials completed0.40.51.8-0.50.30.5-0.7-0.0-0.7-1.4-0.6-0.7-1.2-0.8-0.6-0.8-0.8-0.6-0.70.6-0.8-0.6-0.9
Reaction time trials AUC0.40.61.9-0.60.40.4-0.80.0-0.7-1.4-0.6-0.8-1.3-0.9-0.6-0.9-0.8-0.6-0.70.7-0.8-0.6-0.9
Social response proportion0.20.21.50.5-0.41.20.3-0.20.50.30.30.40.60.50.40.4-0.40.40.4-0.20.40.40.3
Social responses0.20.30.80.6-0.30.30.5-0.90.60.50.20.50.80.60.40.6-0.50.40.4-0.20.60.50.7
Social time0.81.14.7-0.80.22.0-0.70.3-0.9-2.2-0.3-1.0-1.5-0.7-0.5-1.20.4-1.2-0.60.2-1.1-0.7-1.4
Conditioned locomotion3.03.64.5-2.02.1-1.6-2.01.3-2.0-2.0-2.1-2.0-1.5-2.1-2.1-1.8-0.2-1.9-2.12.1-2.0-2.1-1.9
Cocaine response after cond. corrected0.60.73.20.7-1.11.70.7-1.80.5-0.71.00.5-0.40.50.80.40.20.50.7-1.00.50.80.4
Cocaine response after cond. not corrected2.32.67.31.6-2.02.71.6-2.31.50.11.81.50.71.51.71.40.21.41.6-1.81.51.71.3
Cocaine response before conditioning1.11.32.81.1-0.90.91.2-0.01.31.51.11.21.71.31.11.30.21.11.2-1.11.31.21.2
Saline control response0.91.22.01.3-0.9-0.71.0-1.01.31.40.71.21.11.31.01.0-1.21.41.0-0.61.21.11.4
Condit. Reinf. active minus inactive responses2.43.07.41.7-1.60.41.80.21.72.71.91.91.91.91.81.71.01.61.9-2.01.81.81.7
Condit. Reinf. active-inactive response ratio1.81.92.71.5-1.61.51.5-1.41.40.81.61.40.91.51.61.20.31.21.5-1.61.51.51.3
Condit. Reinf. active responses1.92.78.11.6-1.60.11.60.41.62.81.91.81.51.71.81.50.91.61.8-1.91.61.71.6
Condit. Reinf. inactive responses0.30.43.4-0.20.2-1.3-0.21.8-0.21.50.10.00.0-0.1-0.0-0.10.60.00.1-0.1-0.2-0.1-0.1
Condit. Reinf. lever presses2.53.48.81.8-1.70.41.9-0.01.93.02.02.01.92.02.01.80.61.82.0-2.02.01.91.9
Condit. Reinf. lever reinforcers received2.23.08.01.7-1.70.41.80.11.72.82.01.91.61.91.91.60.71.71.9-2.01.81.81.7
Pavlov. Cond. lever latency0.60.82.1-0.90.8-0.3-1.0-0.2-0.9-1.4-1.0-1.0-1.1-1.0-1.0-0.9-0.5-0.8-1.01.0-1.0-0.9-0.9
Pavlov. Cond. magazine entry latency0.10.10.8-0.30.30.2-0.10.9-0.20.40.0-0.1-0.0-0.1-0.1-0.20.4-0.3-0.1-0.0-0.0-0.2-0.2
Pavlov. Cond. change in total contacts2.83.98.62.0-1.91.02.1-0.22.02.92.22.22.02.22.11.90.81.92.2-2.22.12.12.0
Pavlov. Cond. index score0.30.41.20.4-0.40.40.60.70.51.10.70.60.70.60.60.50.80.30.6-0.80.60.50.4
Pavlov. Cond. latency score0.20.31.10.3-0.30.30.50.70.41.00.60.50.60.50.50.40.70.20.5-0.70.50.40.4
Pavlov. Cond. lever contacts1.01.43.11.2-1.00.51.2-0.11.31.81.21.31.31.51.21.1-0.01.11.2-1.21.41.21.2
Pavlov. Cond. magazine entry number0.20.21.20.5-0.50.10.4-1.10.4-0.10.20.30.30.30.30.4-0.40.50.3-0.20.30.40.5
Pavlov. Cond. intertrial magazine entries0.40.51.5-0.70.6-1.2-0.70.5-0.8-0.4-0.7-0.7-0.4-0.9-0.7-0.50.3-0.5-0.70.7-0.9-0.7-0.6
Pavlov. Cond. lever-magazine prob. diff.0.30.31.00.4-0.40.50.60.60.41.00.70.50.50.60.60.40.70.30.6-0.70.60.50.4
Pavlov. Cond. response bias0.20.31.30.4-0.30.10.50.70.51.10.60.50.50.60.50.30.30.30.5-0.60.60.50.4
Conditioned reinforcement - actives0.40.42.3-0.30.31.0-0.60.6-0.5-0.4-0.4-0.3-1.0-0.7-0.3-0.8-1.5-0.0-0.40.4-0.0-0.3-0.5
Conditioned reinforcement - inactives0.60.72.6-0.70.21.4-0.60.1-1.0-1.6-0.2-0.8-1.4-1.0-0.5-0.80.7-0.8-0.50.2-0.8-0.6-1.0
Conditioned locomotion0.81.06.1-0.60.7-0.1-1.0-0.5-0.6-0.7-1.0-0.7-1.6-0.8-0.8-1.3-2.5-0.4-0.91.1-0.4-0.6-0.6
Intermittent access intake day 1-15 change0.30.31.3-0.5-0.10.9-0.30.6-0.7-0.70.2-0.4-0.9-0.9-0.1-0.51.2-0.5-0.1-0.2-0.5-0.3-0.6
Intermittent access intake escalation0.30.21.0-0.4-0.10.9-0.20.5-0.6-0.50.2-0.3-0.8-0.7-0.1-0.41.0-0.4-0.1-0.3-0.4-0.2-0.5
Intermittent access intake escalation 20.50.53.30.4-0.91.80.40.60.10.21.00.4-0.40.00.70.10.80.30.7-1.10.40.60.0
Intermitt. access day 1 inactive lever presses0.10.22.10.1-0.10.7-0.0-1.40.0-0.5-0.1-0.1-0.30.0-0.0-0.1-0.4-0.2-0.10.1-0.1-0.0-0.1
Intermitt. access day 15 inactive lever presses0.60.63.3-0.80.40.3-0.40.1-0.9-1.3-0.3-0.8-0.4-0.8-0.6-0.41.8-1.0-0.50.2-1.0-0.7-0.9
Intermitt. access escalation Index0.20.21.90.00.3-1.40.0-0.70.2-0.0-0.4-0.00.30.2-0.20.1-0.2-0.0-0.20.40.0-0.10.4
Intermittent access day 1 total infusions0.00.00.1-0.00.1-0.3-0.1-0.4-0.0-0.2-0.1-0.1-0.1-0.1-0.1-0.0-0.30.0-0.10.20.0-0.10.0
Intermittent access day 15 total infusions0.10.10.5-0.30.10.2-0.3-0.1-0.5-0.5-0.1-0.3-0.7-0.7-0.2-0.40.1-0.2-0.20.1-0.2-0.2-0.2
Intermittent access terminal intake (last 3 days)0.10.10.3-0.1-0.10.3-0.1-0.6-0.2-0.5-0.0-0.1-0.6-0.5-0.0-0.2-0.30.0-0.10.00.0-0.0-0.1
Intermittent access total infusions0.20.20.6-0.40.3-0.1-0.4-0.7-0.5-0.8-0.3-0.4-0.7-0.8-0.4-0.4-0.0-0.3-0.40.4-0.3-0.4-0.3
Intermittent access day 1 locomotion0.40.42.6-0.30.4-0.0-0.6-0.0-0.3-0.3-0.6-0.4-1.0-0.3-0.4-0.8-1.6-0.3-0.50.6-0.3-0.4-0.5
Intermittent access day 15 total locomotion0.80.83.0-0.70.8-0.3-1.0-0.1-0.7-1.0-1.0-0.8-1.4-0.8-0.8-1.1-1.7-0.6-1.01.1-0.6-0.7-0.7
Intermittent access total locomotion1.31.52.5-1.11.2-0.8-1.3-0.6-1.1-1.4-1.4-1.2-1.6-1.3-1.2-1.4-1.6-1.0-1.31.5-0.9-1.1-1.0
Intermittent access standard deviation0.91.07.00.7-1.22.60.70.30.40.81.40.80.10.31.10.30.90.71.1-1.50.60.90.2
Cocaine induced anxiety0.50.51.6-0.70.4-0.1-0.70.4-0.9-1.3-0.5-0.8-1.2-0.8-0.6-0.80.3-0.7-0.70.5-0.7-0.7-0.9
Post-drug Anxiety0.40.41.4-0.60.4-0.4-0.6-0.1-0.6-1.0-0.5-0.7-1.2-0.5-0.5-0.8-0.1-0.7-0.60.5-0.7-0.6-0.7
Baseline Anxiety0.20.20.5-0.40.5-0.7-0.4-0.2-0.3-0.2-0.5-0.4-0.3-0.3-0.5-0.40.0-0.5-0.50.5-0.5-0.5-0.4
Lifetime Intake0.20.20.9-0.40.3-0.1-0.4-0.9-0.4-0.7-0.4-0.4-0.7-0.7-0.4-0.5-0.5-0.3-0.50.5-0.3-0.4-0.3
Incentive Sensitization - Responses1.41.42.5-1.20.9-1.1-1.21.0-1.3-1.1-0.9-1.3-1.6-1.3-1.1-1.30.6-1.4-1.10.9-1.4-1.2-1.3
Incentive Sensitization - Breakpoint1.31.32.4-1.20.9-1.0-1.11.0-1.3-1.1-0.9-1.3-1.5-1.3-1.1-1.30.6-1.3-1.10.8-1.4-1.2-1.3
Progressive ratio test 1 active lever presses0.10.11.50.00.10.2-0.2-0.70.1-0.3-0.3-0.0-0.3-0.1-0.1-0.2-1.20.2-0.20.40.2-0.00.2
Progressive ratio test 1 breakpoint0.20.21.4-0.10.2-0.0-0.2-0.9-0.0-0.6-0.4-0.2-0.4-0.2-0.3-0.2-1.20.1-0.30.50.1-0.10.1
Progressive ratio test 1 inactive lever presses0.30.31.1-0.50.21.1-0.50.6-0.6-0.8-0.2-0.5-0.9-0.7-0.3-0.7-0.0-0.4-0.30.1-0.5-0.4-0.8
Progressive ratio test 2 active lever presses0.70.71.6-0.90.8-0.6-1.00.5-0.9-0.8-0.8-0.9-1.3-1.1-0.8-1.1-0.5-0.8-0.90.8-0.8-0.8-0.9
Progressive ratio test 2 breakpoint0.50.61.4-0.80.6-0.6-0.80.5-0.8-0.8-0.7-0.8-1.2-1.0-0.7-0.9-0.2-0.7-0.80.7-0.7-0.7-0.7
Progressive ratio test 2 inactive lever presses1.21.43.3-1.20.70.4-1.10.6-1.5-1.7-0.7-1.2-1.8-1.6-0.9-1.30.6-1.3-1.00.6-1.2-1.1-1.5
Total sessions with >9 infusions0.50.67.40.2-0.61.10.2-2.70.0-1.10.4-0.0-0.7-0.30.20.10.3-0.00.1-0.4-0.20.20.0
Short access day 1 total inactive lever presses2.12.35.4-1.61.2-0.7-1.50.6-1.8-2.3-1.4-1.7-1.9-1.9-1.5-1.50.3-1.6-1.51.3-1.6-1.6-1.5
Short access day 10 total inactive lever presses0.10.20.8-0.1-0.30.90.00.1-0.2-0.10.5-0.1-0.30.00.2-0.10.9-0.30.2-0.5-0.20.1-0.6
Short access day 1 total infusions0.70.81.7-0.80.6-0.4-0.8-1.3-0.9-1.3-0.8-0.9-1.2-1.0-0.8-0.9-0.0-0.9-0.90.8-0.9-0.8-0.8
Short access day 10 total infusions0.20.23.50.1-0.1-0.30.1-1.90.0-0.5-0.10.0-0.2-0.3-0.00.1-0.30.1-0.10.10.10.00.3
Short access total infusions0.50.61.8-0.50.6-0.5-0.7-1.3-0.6-1.1-0.8-0.7-1.0-0.8-0.7-0.7-0.9-0.5-0.80.8-0.6-0.6-0.4
Short access day 1 locomotion0.60.710.40.0-0.10.1-0.1-3.2-0.1-1.0-0.2-0.2-0.9-0.3-0.1-0.2-0.9-0.1-0.30.3-0.1-0.1-0.0
Short access day 10 total locomotion0.30.33.30.20.1-0.1-0.0-1.80.3-0.3-0.30.10.00.1-0.10.1-1.40.3-0.20.40.30.00.3
Short access total locomotion0.70.75.5-0.00.2-0.2-0.4-2.30.0-0.6-0.6-0.2-1.0-0.2-0.3-0.5-2.30.0-0.50.7-0.0-0.2-0.0
Compulsive drug intake0.20.20.8-0.20.5-0.9-0.3-0.3-0.0-0.2-0.6-0.3-0.1-0.0-0.4-0.3-0.7-0.2-0.50.7-0.2-0.30.0
One hour access (0.3 mA shock)0.30.32.4-0.20.30.1-0.4-0.8-0.2-0.5-0.5-0.2-0.9-0.5-0.3-0.7-1.6-0.1-0.40.5-0.0-0.2-0.2
One hour access (shock baseline)0.10.10.60.0-0.10.7-0.10.4-0.20.10.10.0-0.5-0.30.1-0.4-0.50.10.1-0.10.20.1-0.1
Number of responses in last shaping day0.40.42.3-0.60.3-1.0-0.4-0.2-0.8-0.8-0.2-0.6-0.7-0.9-0.4-0.41.5-0.7-0.40.2-0.7-0.5-0.4
Context. condit. distance diff. score0.10.11.2-0.0-0.0-0.30.11.1-0.00.70.30.20.30.00.20.20.80.10.2-0.30.00.10.0
Locomotion velocity, session 10.10.20.8-0.30.4-0.2-0.40.9-0.20.1-0.4-0.2-0.3-0.1-0.3-0.4-0.9-0.2-0.30.4-0.1-0.3-0.4
Locomotion distance, session 10.81.03.50.9-0.50.30.80.61.11.90.71.11.21.20.80.8-1.31.00.8-0.61.30.91.0
Locomotion velocity, session 20.20.31.9-0.60.7-0.5-0.41.4-0.50.2-0.4-0.4-0.0-0.4-0.5-0.40.3-0.6-0.40.4-0.4-0.5-0.5
Locomotion distance, session 20.20.32.1-0.10.6-1.1-0.30.90.10.6-0.5-0.00.10.2-0.3-0.2-1.4-0.1-0.30.50.2-0.10.0
Locomotion velocity, session 30.10.10.60.10.3-0.30.20.60.40.7-0.10.30.70.40.10.2-0.80.20.10.10.50.10.3
Locomotion distance, session 31.21.24.9-1.21.5-2.2-0.92.1-0.90.1-1.2-0.9-0.0-0.8-1.1-0.80.1-1.1-1.01.1-0.8-1.1-0.8
Stereotopy head waving bouts, day 30.50.63.50.5-1.11.90.6-1.10.2-0.61.00.4-0.40.20.70.41.10.30.7-1.00.20.60.2
Stereotopy head waving duration, day 30.60.72.80.8-1.21.70.7-1.50.6-0.31.00.6-0.10.50.90.50.30.70.8-1.00.50.80.5
Locomotion velocity, session 70.30.31.30.40.0-1.10.20.20.51.1-0.00.50.80.60.20.4-1.00.60.20.10.60.30.6
Locomotion distance, session 71.01.26.7-1.01.2-2.6-1.11.2-0.80.0-1.2-0.8-0.8-0.8-1.0-1.0-1.1-0.8-1.11.2-0.7-1.0-0.7
Stereotopy head waving bouts, day 70.30.30.7-0.50.8-0.8-0.60.4-0.4-0.3-0.8-0.5-0.1-0.3-0.7-0.5-0.7-0.4-0.60.8-0.4-0.6-0.4
Stereotopy head waving duration, day 70.10.10.50.3-0.00.10.3-0.10.40.40.00.30.70.50.20.4-0.50.40.2-0.00.40.20.4
Locomotion velocity, session 80.60.73.80.40.0-0.40.61.60.62.00.50.71.40.70.50.70.40.50.6-0.50.90.50.6
Locomotion distance, session 80.40.62.90.40.2-1.00.31.30.71.70.10.60.90.80.30.4-1.20.50.3-0.10.90.40.6
Degree of sensitization distance1.01.02.21.2-1.30.80.8-1.51.10.70.91.00.21.01.10.7-0.91.21.0-0.91.01.11.0
Degree of sensitization stereotypy0.30.41.6-0.30.9-1.3-0.50.7-0.20.2-0.9-0.30.3-0.1-0.6-0.3-1.1-0.2-0.60.9-0.2-0.5-0.2
Condit. Reinf. active minus inactive responses0.10.10.20.3-0.50.10.2-0.20.20.40.40.3-0.00.20.40.20.10.40.3-0.40.20.30.3
Condit. Reinf. active-inactive response ratio0.20.30.60.6-0.80.50.5-0.50.40.50.60.50.10.40.60.40.30.60.6-0.60.40.60.4
Condit. Reinf. active responses0.10.10.2-0.20.1-0.3-0.30.1-0.3-0.4-0.2-0.3-0.4-0.3-0.2-0.3-0.0-0.2-0.20.2-0.2-0.2-0.2
Condit. Reinf. inactive responses0.80.91.6-1.01.0-0.8-0.90.6-1.0-1.3-1.0-1.0-0.8-1.0-1.0-0.9-0.2-1.0-1.11.0-0.9-1.0-0.9
Incentive salience index mean0.10.10.3-0.20.2-0.4-0.30.1-0.3-0.1-0.2-0.3-0.5-0.3-0.2-0.3-0.2-0.2-0.30.2-0.2-0.2-0.2
Condit. Reinf. lever presses1.31.72.1-1.41.4-1.2-1.40.8-1.3-1.4-1.4-1.4-1.4-1.3-1.4-1.4-0.5-1.4-1.41.4-1.2-1.4-1.3
Time in familiar zone, hab. session 10.80.81.5-0.90.6-0.3-0.90.1-1.1-1.1-0.6-0.9-1.1-1.2-0.8-0.90.9-0.8-0.80.6-1.2-0.9-1.0
Time in novel zone, hab. session 10.30.31.00.6-0.60.80.5-0.70.6-0.00.50.50.10.70.60.3-1.00.50.5-0.50.70.60.4
Total zone transitions, hab. session 10.50.73.00.8-0.50.40.6-0.81.00.60.40.80.61.10.60.6-1.70.80.5-0.31.10.80.8
Total locomotion distance, hab. session 10.10.20.80.5-0.30.00.4-0.40.60.50.30.50.40.60.40.3-0.90.40.4-0.20.60.50.5
Locomotion velocity, hab. session 10.20.30.80.5-0.1-0.30.40.10.60.90.20.50.80.70.30.4-0.80.50.3-0.20.60.40.5
Time in familiar zone, hab. session 20.50.53.5-0.60.3-0.7-0.31.9-0.70.5-0.0-0.4-0.1-0.6-0.3-0.31.7-0.5-0.2-0.0-0.6-0.4-0.6
Time in novel zone, hab. session 20.40.53.30.2-0.20.9-0.1-1.80.2-1.2-0.2-0.1-0.60.1-0.0-0.2-1.70.1-0.20.30.10.10.1
Total zone transitions, hab. session 20.10.22.00.3-0.10.20.1-0.30.40.20.10.2-0.10.60.2-0.1-1.40.10.1-0.00.50.30.2
Total locomotion distance, hab. session 20.20.31.00.5-0.1-0.10.40.10.61.00.30.50.70.70.40.4-0.60.40.4-0.30.70.40.5
Locomotion velocity, hab. session 20.20.21.30.30.1-0.50.20.50.51.10.10.40.60.60.20.2-0.60.30.2-0.10.50.30.4
Novel to familiar place preference ratio0.70.75.00.8-0.2-0.20.4-1.11.00.8-0.00.70.91.00.40.5-2.20.90.30.20.90.61.1
Novelty place preference0.70.75.40.8-0.1-0.40.4-1.11.00.8-0.10.70.91.00.30.5-2.30.90.30.30.90.61.1
Time in novel zone, NPP test0.90.95.11.0-0.40.00.6-1.41.10.70.10.80.81.10.50.6-2.31.10.40.01.00.71.2
Total zone transitions, NPP test1.92.75.21.7-1.21.01.5-1.22.01.81.31.71.32.11.61.3-2.31.61.4-1.22.21.71.7
Total locomotion distance, NPP test0.71.01.61.1-0.80.61.1-0.71.21.20.91.11.11.31.01.0-0.61.01.0-0.91.31.11.1
Locomotion velocity, NPP test0.81.12.51.1-0.70.21.1-0.31.21.60.91.21.31.31.01.0-0.71.01.0-0.91.31.11.1
Pavlov. Cond. lever latency4.35.47.02.6-2.62.22.4-2.62.51.62.42.51.82.52.52.3-0.62.62.4-2.32.42.62.4
Pavlov. Cond. magazine entry latency5.26.79.8-2.92.8-1.9-2.73.1-2.9-1.8-2.5-2.8-2.3-2.8-2.7-2.70.8-2.9-2.62.4-2.7-2.8-2.9
Pavlov. Cond. change in total contacts1.51.64.1-1.41.4-1.9-1.12.0-1.40.0-1.1-1.1-0.3-1.4-1.3-0.91.4-1.2-1.11.1-1.3-1.3-1.1
Pavlov. Cond. index score5.26.711.1-2.92.8-2.4-2.63.3-2.9-1.5-2.5-2.7-2.0-2.8-2.7-2.51.1-2.8-2.62.4-2.7-2.8-2.8
Pavlov. Cond. latency score5.36.711.6-2.92.9-2.6-2.63.4-2.8-1.4-2.5-2.7-2.0-2.8-2.7-2.51.0-2.8-2.62.4-2.6-2.8-2.7
Pavlov. Cond. lever contacts2.53.04.3-2.02.0-1.7-1.72.1-1.8-1.1-1.8-1.8-1.2-1.8-1.9-1.60.5-1.9-1.81.7-1.7-1.9-1.7
Pavlov. Cond. magazine entry number6.17.69.33.1-2.92.22.9-3.03.12.02.72.92.53.02.92.9-0.63.02.8-2.62.93.03.0
Pavlov. Cond. intertrial magazine entries0.30.40.60.7-0.70.40.6-0.40.70.50.60.70.50.70.70.6-0.40.80.7-0.60.70.70.7
Pavlov. Cond. lever-magazine prob. diff.4.45.69.6-2.72.5-2.0-2.43.1-2.7-1.3-2.1-2.5-1.9-2.6-2.4-2.31.4-2.6-2.32.0-2.5-2.5-2.6
Pavlov. Cond. response bias5.46.68.4-2.92.7-1.6-2.72.4-2.9-2.2-2.5-2.8-2.4-2.9-2.7-2.70.8-2.9-2.72.4-2.7-2.8-2.8
Bone: apparent density0.10.11.00.00.3-1.0-0.00.50.20.8-0.20.10.50.2-0.10.1-0.50.2-0.10.30.3-0.00.3
Bone surface0.10.21.1-0.30.4-1.0-0.20.9-0.20.5-0.3-0.20.0-0.2-0.3-0.20.1-0.3-0.20.2-0.1-0.3-0.1
Bone volume0.10.21.2-0.20.4-1.1-0.11.0-0.10.7-0.2-0.00.3-0.0-0.2-0.00.2-0.2-0.10.20.1-0.20.0
Bone: connectivity density0.50.71.8-0.71.0-1.3-1.00.4-0.6-0.3-1.1-0.7-0.6-0.7-0.9-0.8-1.2-0.6-1.01.2-0.6-0.8-0.5
Bone: cortical apparent density0.70.95.3-0.81.1-1.8-0.82.3-0.80.7-0.8-0.6-0.1-0.7-0.8-0.60.4-0.6-0.70.8-0.7-0.8-0.7
Bone: cortical area0.20.34.8-0.3-0.00.00.10.8-0.40.10.3-0.20.1-0.40.00.12.2-0.40.1-0.4-0.4-0.2-0.3
Bone: cortical porosity0.50.64.2-0.30.7-0.8-0.7-0.4-0.2-0.6-1.1-0.5-0.3-0.3-0.7-0.6-2.0-0.1-0.81.2-0.4-0.5-0.3
Bone: cortical porosity0.80.84.6-0.50.8-0.6-0.9-0.7-0.4-1.1-1.2-0.7-0.7-0.5-0.9-0.8-2.1-0.3-1.01.3-0.6-0.7-0.5
Bone: cortical thickness0.61.07.70.4-0.70.10.91.10.31.31.20.71.00.40.81.02.80.41.0-1.30.40.60.5
Bone: cortical thickness0.10.10.70.1-0.0-0.80.10.60.10.40.10.10.10.10.10.10.20.10.1-0.10.10.10.1
Bone: cortical tissue density0.70.95.4-0.91.1-1.8-0.82.3-0.80.7-0.9-0.7-0.0-0.7-0.8-0.60.4-0.7-0.70.8-0.7-0.9-0.7
Bone: elastic displacement0.30.42.40.3-0.50.60.60.50.20.40.70.40.60.30.50.61.60.30.6-0.80.20.40.2
Bone: elastic work1.21.64.80.9-1.01.11.40.70.91.31.41.11.71.01.21.52.20.81.3-1.51.01.10.9
Bone: endosteal estimation0.10.20.70.5-0.40.30.4-0.90.50.00.30.40.60.50.40.5-0.30.50.4-0.20.40.40.5
Bone: endosteal perimeter0.91.94.7-1.41.3-0.3-1.40.1-1.4-2.2-1.4-1.6-1.4-1.5-1.5-1.4-0.3-1.5-1.51.4-1.5-1.5-1.5
Bone: final force1.11.83.01.2-1.31.11.5-0.21.21.31.51.31.51.21.41.51.71.11.5-1.61.21.31.2
Bone: final moment1.42.33.41.4-1.61.41.7-0.51.41.41.81.51.61.41.61.71.81.31.7-1.91.41.51.4
Bone: marrow area0.10.20.80.5-0.40.30.5-0.90.50.10.30.50.60.50.40.5-0.40.50.4-0.20.50.50.5
Bone: maximum diameter0.20.41.3-0.70.50.0-0.50.6-0.8-0.6-0.4-0.7-0.6-0.8-0.6-0.61.1-0.8-0.50.3-0.8-0.7-0.8
Bone: maximum force0.81.52.51.1-1.20.71.4-0.41.11.21.31.21.61.11.21.51.41.11.3-1.31.11.21.2
Bone: maximum moment1.01.72.61.2-1.31.01.5-0.71.21.11.41.31.61.21.41.61.41.21.4-1.51.21.31.3
Bone: minimum diameter0.20.41.5-0.60.50.1-0.5-0.2-0.6-1.2-0.5-0.7-0.6-0.7-0.6-0.50.5-0.7-0.60.5-0.7-0.6-0.6
Bone: periosteal estimation0.10.21.20.3-0.30.20.4-0.00.20.30.50.30.50.20.40.51.10.20.4-0.50.20.30.3
Bone: periosteal perimeter0.81.41.9-1.31.2-0.7-1.10.8-1.3-1.4-1.1-1.3-0.9-1.3-1.2-1.00.7-1.3-1.21.1-1.3-1.3-1.3
Bone: post-yield work0.10.11.30.3-0.30.50.2-1.20.3-0.40.10.20.10.30.20.2-0.40.20.1-0.10.30.20.3
Bone: stiffness0.10.20.60.4-0.3-0.30.4-0.00.40.70.30.40.60.40.40.50.30.50.4-0.30.40.40.5
Bone: tissue strength4.03.95.71.8-2.01.42.2-0.61.82.42.22.02.41.82.12.22.01.82.2-2.31.82.01.9
Bone: trabecular number0.81.23.5-1.11.4-1.9-1.11.4-0.9-0.1-1.3-1.0-0.6-0.9-1.2-1.0-0.8-1.0-1.11.3-0.8-1.1-0.8
Bone: trabecular spacing1.51.93.51.4-1.61.91.5-1.41.30.81.61.31.11.31.51.41.01.31.5-1.61.21.41.2
Bone: trabecular thickness0.20.21.0-0.00.5-0.90.01.00.11.0-0.30.10.80.2-0.10.2-0.10.0-0.10.30.2-0.10.2
Bone: trabecular tissue density0.20.21.10.4-0.2-0.40.20.30.51.10.20.40.30.60.30.2-1.00.50.3-0.10.50.40.4
Breakpoint value in progressive ratio session0.10.10.80.10.20.40.10.40.20.9-0.00.20.80.30.00.2-0.00.20.10.00.30.10.1
Distance traveled before self-admin0.50.53.50.4-0.80.80.6-1.90.2-0.60.80.30.00.00.60.71.50.40.6-0.80.30.50.4
Distance traveled after self-admin0.40.44.6-0.50.40.3-0.62.1-0.60.0-0.2-0.4-0.5-0.5-0.3-0.7-0.2-0.4-0.30.2-0.5-0.4-0.9
Delta time in closed arm before/after self-admin0.30.31.7-0.30.3-1.3-0.2-1.2-0.2-0.5-0.5-0.4-0.4-0.4-0.4-0.2-0.0-0.4-0.50.5-0.4-0.40.0
Delta time in open arm before/after self-admin0.60.65.20.30.00.60.12.30.41.50.30.51.10.50.30.1-0.60.50.4-0.30.40.30.0
Diff in mean of infusions in LGA sessions0.10.11.00.0-0.40.80.20.2-0.10.00.50.0-0.2-0.10.20.01.0-0.20.3-0.5-0.20.1-0.3
Extinction: sum of active levers before priming0.20.22.60.2-0.0-0.50.2-1.60.3-0.3-0.20.10.20.10.00.4-0.20.3-0.00.20.30.10.6
Active lever presses in extinction session 60.40.43.00.6-0.5-0.40.6-1.70.70.20.20.50.30.60.40.7-0.40.70.4-0.20.50.51.0
Delta distance traveled before/after self-admin0.80.97.0-0.70.9-0.6-0.92.7-0.50.4-0.8-0.6-0.4-0.4-0.7-1.1-1.3-0.6-0.70.8-0.6-0.7-0.9
Delta ambulatory time before/after self-admin0.60.77.10.30.10.2-0.12.70.41.40.00.30.40.60.2-0.3-1.70.20.2-0.00.30.3-0.1
Time in closed arm before self-admin1.82.14.21.5-1.62.01.40.51.31.01.61.51.11.31.61.4-0.31.71.6-1.61.61.61.3
Time in closed arm after self-admin0.10.10.20.2-0.40.00.2-0.40.2-0.40.30.2-0.30.00.30.3-0.20.30.2-0.20.30.30.3
Time in open arm before self-admin1.31.42.7-1.11.0-1.6-1.1-0.9-1.0-1.4-1.2-1.3-1.7-1.0-1.2-1.2-0.1-1.4-1.31.2-1.3-1.2-1.0
Time in open arm after self-admin0.91.04.4-0.71.3-0.7-1.02.1-0.50.6-1.1-0.6-0.0-0.4-0.9-1.1-1.9-0.5-0.91.2-0.4-0.8-0.8
Sum of active levers in priming session hrs 5-60.30.30.90.6-0.30.30.3-0.30.60.90.30.50.40.70.40.3-1.00.70.4-0.30.60.50.5
Time to tail flick, vehicle, before self-admin2.12.16.21.5-1.51.31.5-2.51.40.71.41.40.91.41.41.50.21.51.4-1.31.51.51.7
Time to tail flick, vehicle, after self-admin0.80.83.70.7-0.71.90.71.00.61.01.00.81.20.80.90.50.70.70.9-1.10.50.80.3
Time to tail flick, test, before self-admin0.60.63.8-0.10.4-0.9-0.4-1.90.2-0.7-0.8-0.4-0.70.4-0.5-0.5-1.8-0.3-0.60.9-0.4-0.3-0.1
Time to tail flick, test, after self-admin0.20.21.0-0.20.10.5-0.0-0.7-0.4-0.8-0.0-0.20.0-0.4-0.10.01.0-0.3-0.10.0-0.4-0.2-0.2
Delta time to tail flick, vehicle, before/after SA0.60.64.6-0.70.70.5-0.62.2-0.8-0.0-0.3-0.60.1-0.6-0.5-0.71.0-0.8-0.40.2-0.8-0.6-1.1
Delta time to tail flick, test, before/after SA0.30.33.2-0.20.10.50.10.3-0.5-0.30.2-0.10.6-0.7-0.00.31.8-0.10.1-0.2-0.0-0.1-0.0
Ambulatory time before self-admin0.40.42.90.1-0.50.40.4-1.7-0.1-0.90.50.0-0.1-0.30.30.51.60.10.3-0.50.10.20.2
Ambulatory time after self-admin0.20.33.6-0.20.3-0.0-0.41.9-0.20.2-0.2-0.2-0.2-0.1-0.2-0.5-0.8-0.1-0.20.2-0.1-0.2-0.4
Total heroin consumption1.31.64.31.3-1.32.11.2-0.31.21.51.41.21.31.31.31.10.51.11.4-1.41.01.30.9
Area under the delay curve2.52.63.7-1.71.8-1.9-1.71.2-1.6-1.5-1.9-1.7-1.4-1.5-1.8-1.6-0.6-1.5-1.81.9-1.6-1.7-1.5
Delay disc. indifference point, 0s delay0.20.22.1-0.00.10.2-0.0-1.5-0.1-0.9-0.2-0.1-0.2-0.1-0.10.10.0-0.0-0.20.2-0.1-0.10.1
Delay disc. indifference point, 16s delay1.41.43.0-1.21.3-1.7-1.21.6-1.1-0.7-1.3-1.1-1.0-1.0-1.2-1.2-0.5-1.1-1.21.3-1.1-1.2-1.1
Delay disc. indifference point, 2s delay0.30.30.7-0.60.7-0.1-0.6-0.1-0.7-0.8-0.7-0.6-0.5-0.6-0.7-0.6-0.1-0.5-0.70.7-0.6-0.6-0.5
Delay disc. indifference point, 24s delay1.31.23.8-1.01.1-1.1-1.22.0-1.1-0.9-1.1-1.0-1.1-1.0-1.1-1.2-0.8-1.0-1.11.1-0.9-1.0-1.2
Delay disc. indifference point, 4s delay2.22.32.9-1.61.7-1.7-1.61.1-1.7-1.3-1.6-1.6-1.3-1.6-1.6-1.50.1-1.6-1.61.6-1.6-1.6-1.5
Delay disc. indifference point, 8s delay2.32.43.5-1.61.7-1.9-1.60.9-1.6-1.7-1.8-1.6-1.4-1.5-1.7-1.5-0.4-1.5-1.71.8-1.5-1.6-1.4
Delay discount exponential model param2.82.93.91.8-1.92.01.8-1.31.81.61.91.81.51.71.91.70.41.71.9-1.91.71.81.6
Delay discount hyperbolic model param2.72.93.71.8-1.91.91.8-1.21.81.61.91.81.51.71.91.70.51.71.9-1.91.71.81.6
Fecal boli incidents, locomotor time 10.70.71.60.8-0.70.50.9-0.70.71.00.90.81.10.70.81.01.30.60.9-0.90.70.70.9
Change in fecal boli incidents, locomotor task0.10.10.90.1-0.00.30.1-0.90.2-0.1-0.00.10.30.20.00.4-0.30.20.00.10.20.10.3
Time >=10cm from walls, locomotor time 10.40.41.6-0.60.7-1.3-0.60.3-0.4-0.3-0.8-0.5-0.3-0.4-0.7-0.6-1.0-0.6-0.70.8-0.5-0.6-0.5
Bouts of movement, locomotor time 10.10.11.10.0-0.00.3-0.01.00.10.90.10.10.10.00.1-0.1-0.10.10.1-0.10.10.10.0
Total resting periods, locomotor time 10.10.10.90.1-0.10.40.11.00.10.70.20.10.20.00.1-0.00.10.20.2-0.20.10.10.1
Rest time, locomotor task time 10.50.61.6-0.70.6-0.2-0.7-0.8-0.7-1.3-0.8-0.8-0.9-0.9-0.8-0.6-0.3-0.5-0.80.8-0.6-0.7-0.4
Distance moved, locomotor task time 11.71.93.01.4-1.41.51.5-0.51.31.41.61.41.71.41.51.51.01.21.5-1.61.21.41.1
Vertical activity count, locomotor time 10.60.61.40.8-0.70.50.80.00.91.20.80.81.21.00.80.80.30.70.9-0.90.70.80.5
Time >=10cm from walls, locomotor time 21.61.73.01.3-1.10.11.4-1.61.31.71.21.31.71.31.21.50.61.11.3-1.21.11.21.5
Bouts of movement, locomotor time 20.30.32.60.4-0.50.60.6-0.20.20.20.60.40.70.20.50.71.60.20.5-0.60.10.40.5
Total resting periods, locomotor time 20.20.22.40.1-0.20.40.40.0-0.1-0.10.30.10.5-0.10.20.51.6-0.10.2-0.3-0.10.10.3
Rest time, locomotor task time 20.10.10.7-0.20.30.7-0.10.9-0.2-0.0-0.2-0.10.2-0.3-0.2-0.10.10.0-0.20.20.2-0.20.0
Distance moved, locomotor task time 20.80.92.11.0-1.10.71.0-1.40.90.71.10.90.71.01.10.90.30.71.0-1.10.61.00.8
Vertical activity count, locomotor time 20.00.00.30.2-0.2-0.30.1-0.50.20.10.20.1-0.00.30.2-0.1-0.4-0.00.2-0.2-0.10.2-0.0
Weight adjusted by age0.60.71.50.7-1.01.00.9-1.20.60.21.00.70.70.40.81.01.20.60.9-1.00.60.80.7
Seeking ratio, delayed vs. immediate footshock2.32.74.9-1.61.6-2.2-1.6-0.3-1.6-2.2-1.9-1.7-1.8-1.7-1.8-1.5-0.4-1.6-1.81.9-1.4-1.7-1.2
Locomotion in novel chamber0.10.10.6-0.30.10.7-0.2-0.3-0.4-0.6-0.0-0.2-0.3-0.5-0.1-0.10.8-0.1-0.1-0.0-0.3-0.2-0.3
Locomotion in novel chamber post-restriction0.70.81.40.9-0.71.00.8-0.51.01.10.60.91.11.10.80.8-0.41.10.8-0.61.20.91.1
Progressive ratio3.23.75.12.1-1.92.11.9-2.12.11.31.72.01.72.01.92.0-0.92.31.9-1.62.22.02.2
Food seeking constrained by brief footshock0.60.83.1-0.80.6-1.7-0.8-0.1-0.9-1.1-0.7-0.9-1.2-0.9-0.8-0.70.1-0.9-0.80.7-0.9-0.8-0.8
Seeking ratio, punishment vs. effort4.55.57.6-2.52.1-2.7-2.31.4-2.6-2.2-2.1-2.5-2.6-2.6-2.3-2.40.9-2.7-2.32.0-2.7-2.4-2.6
Run reversals in cocaine runway, females1.51.52.4-1.31.1-0.9-1.10.1-1.4-1.5-1.1-1.4-1.1-1.3-1.3-1.10.9-1.5-1.31.1-1.5-1.3-1.3
Run reversals in cocaine runway, males0.60.62.30.5-0.61.50.41.40.51.50.80.60.50.70.70.1-0.00.40.7-0.90.20.60.0
Latency to leave start box in cocaine runway0.30.31.50.4-0.40.70.40.70.51.20.60.50.50.60.50.30.00.40.6-0.60.30.50.2
Latency to leave start box in cocaine runway, F1.61.83.91.2-1.42.01.20.61.11.91.61.31.11.21.51.00.91.11.5-1.71.11.30.8
Latency to leave start box in cocaine runway, M0.70.71.9-0.81.1-1.4-0.80.2-0.6-0.4-1.1-0.8-0.3-0.6-1.0-0.7-0.6-0.8-0.91.1-0.8-0.9-0.6
Cd content in liver2.42.63.71.8-1.91.41.7-1.51.61.51.81.71.21.51.81.60.61.81.8-1.81.51.71.6
Co content in liver0.20.32.10.2-0.4-0.00.50.40.20.50.60.30.60.10.40.61.50.20.5-0.60.10.30.3
Cu content in liver3.94.77.02.4-2.12.62.2-2.32.31.52.02.32.32.32.22.3-0.22.32.2-2.02.32.22.2
Fe content in liver1.82.15.41.4-1.40.11.50.01.22.31.51.51.81.21.51.61.61.61.6-1.61.11.41.4
K content in liver1.11.16.20.6-0.2-0.70.81.70.82.50.71.01.70.90.70.90.70.70.9-0.81.00.70.8
Mg content in liver0.70.76.5-0.10.5-1.30.12.60.02.00.10.20.90.20.00.10.7-0.10.2-0.20.3-0.00.1
Mn content in liver0.80.95.20.7-0.2-0.50.81.10.92.30.61.01.51.00.70.9-0.20.80.8-0.61.10.70.9
Na content in liver0.50.53.40.4-0.2-0.70.41.30.41.80.40.61.10.40.40.60.70.70.5-0.40.30.40.5
Rb content in liver1.21.52.51.2-1.61.21.2-1.01.01.01.41.21.00.81.31.31.31.41.4-1.40.81.21.1
Se content in liver0.20.32.2-0.00.2-0.70.11.5-0.01.20.20.20.60.10.10.10.9-0.10.2-0.20.10.00.0
Sr content in liver0.10.10.40.10.00.60.1-0.40.2-0.40.00.10.10.30.10.0-0.6-0.10.0-0.00.30.10.1
Zn content in liver4.34.77.62.3-2.01.72.4-1.72.41.92.02.32.82.42.22.50.02.32.2-2.02.42.22.4