Incenp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000032929 0.05 0.04 8.3e-03 0.02 0 0.01 0.01 3.1e-03 3.5e-01 4.1e-02 3.4e-02
2 Adipose mRNA stability ENSRNOG00000032929 0.1 0.07 9.3e-04 0.01 0.02 0.02 0.01 4.1e-02 1.3e-03 1.4e-03 6.9e-02
3 Brain alternative TSS ENSRNOT00000043387 0.03 0.03 2.0e-03 0.02 0.02 0.01 0.02 4.0e-03 2.5e-03 2.4e-02 1.1e-02
4 Brain alternative TSS ENSRNOT00000095302 0.03 0.03 1.5e-03 0.02 0.03 0.02 0.02 3.1e-03 1.9e-03 1.2e-02 7.0e-03
5 Brain intron excision ratio chr1:206525320:206525799 0.07 0.05 6.0e-06 0.07 0.06 0.06 0.07 4.4e-07 1.3e-06 2.1e-06 5.5e-07
6 Brain intron excision ratio chr1:206525344:206525799 0.07 0.05 6.0e-06 0.07 0.06 0.06 0.07 4.3e-07 1.4e-06 2.0e-06 5.5e-07
7 Brain mRNA stability ENSRNOG00000032929 0.08 0.05 2.6e-08 0.08 0.08 0.08 0.08 3.8e-08 5.0e-08 6.5e-08 5.2e-08
8 Liver alternative TSS ENSRNOT00000043387 0.03 0.02 4.4e-03 0.01 0 0.01 0 6.8e-02 1.1e-01 6.8e-02 2.0e-01
9 Liver alternative TSS ENSRNOT00000095302 0.03 0.02 5.4e-03 0 0 0 0 7.7e-02 1.3e-01 8.9e-02 2.3e-01
10 Liver gene expression ENSRNOG00000032929 0.04 0.03 2.8e-04 0.02 0.01 0.01 0.01 2.0e-03 9.7e-03 2.1e-02 1.3e-02
11 OFC gene expression ENSRNOG00000032929 0.19 0.13 6.8e-04 0.09 0.09 0.11 0.05 3.5e-03 3.5e-03 1.3e-03 2.5e-02
12 PL alternative TSS ENSRNOT00000043387 0.38 0.17 2.7e-03 0.03 0.03 0.04 0.02 1.5e-03 2.3e-03 7.7e-04 6.2e-03
13 PL alternative TSS ENSRNOT00000095302 0.33 0.17 4.6e-03 0.03 0.03 0.03 0.03 1.3e-03 2.4e-03 2.6e-03 4.5e-03
14 PL gene expression ENSRNOG00000032929 0.09 0.05 3.7e-08 0.07 0.09 0.09 0.09 8.4e-06 1.3e-07 1.7e-07 2.1e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail2.58.018.1-4.2-2.12.7-2.7-2.82.8-2.63.0-3.02.82.43.3-2.81.6
BMI without tail1.53.16.1-1.80.21.6-1.6-2.02.0-1.42.0-2.01.81.72.5-1.81.4
Body weight3.414.318.3-3.1-0.54.1-4.1-4.34.3-3.74.3-4.34.23.33.8-4.23.2
Epididymis fat weight0.41.02.3-1.5-1.5-0.90.90.7-0.71.0-0.80.8-0.9-0.6-0.40.8-1.5
Glucose2.53.96.5-0.6-1.0-2.12.22.0-2.02.3-2.02.0-2.0-2.1-2.02.0-2.5
Heart weight0.40.51.7-0.70.4-0.80.80.5-0.51.3-0.50.5-0.6-0.6-0.10.6-1.1
Left kidney weight0.10.21.2-1.1-0.80.4-0.4-0.40.4-0.10.4-0.40.3-0.0-0.4-0.3-0.2
Right kidney weight0.10.31.0-1.0-0.90.5-0.5-0.50.5-0.40.5-0.50.50.1-0.3-0.5-0.0
Tail length1.23.65.00.52.21.9-1.9-2.12.1-1.62.0-2.01.91.72.0-2.02.2
Length with tail2.07.39.6-1.00.63.1-3.1-3.13.1-2.83.0-3.03.12.52.2-3.12.7
Length without tail1.32.84.1-1.1-0.82.0-2.0-1.81.8-1.91.9-1.92.01.40.7-2.01.4
Liver weight, left0.40.61.90.30.1-0.80.80.7-0.70.8-0.70.7-0.8-1.4-0.70.7-0.8
Liver weight, right0.10.21.0-1.0-0.8-0.20.20.1-0.10.2-0.20.2-0.1-0.80.70.1-0.4
Parametrial fat weight1.73.36.2-1.0-2.2-1.81.81.8-1.81.7-1.81.8-1.8-1.0-2.21.8-2.5
Retroperitoneal fat weight1.96.311.8-1.1-1.4-2.62.62.5-2.53.0-2.42.4-2.5-3.0-2.32.5-3.4
Intraocular pressure0.20.31.31.11.0-0.40.40.4-0.40.3-0.40.4-0.40.4-0.40.4-0.0
Extensor digitorum longus weight5.421.525.9-2.8-0.15.0-5.0-5.05.0-5.15.0-5.05.14.54.8-5.14.5
Soleus weight2.67.69.71.0-0.8-2.92.93.0-3.02.8-3.03.0-2.9-3.1-2.92.9-2.8
Tibialis anterior weight8.830.337.8-1.81.36.1-6.1-6.06.0-6.16.1-6.16.24.95.1-6.15.9
Tibia length1.02.85.3-1.1-1.62.0-2.0-1.71.7-2.31.6-1.61.81.7-0.0-1.81.5
Number of licking bursts0.00.00.1-0.00.1-0.00.00.1-0.10.2-0.10.10.00.1-0.4-0.0-0.1
Food consumed during 24 hour testing period0.40.41.10.5-0.4-0.60.60.7-0.70.5-0.70.7-0.7-0.4-1.00.7-0.5
Times rat made contact with spout0.30.41.40.71.20.3-0.3-0.40.4-0.20.5-0.50.50.70.7-0.50.7
Mean time between licks in bursts1.11.68.0-0.31.50.9-0.9-1.11.1-0.61.0-1.01.21.12.8-1.21.1
Mean num. licks in bursts0.10.20.90.81.0-0.10.1-0.00.00.10.1-0.1-0.10.10.60.10.3
Std. dev. time between licks in bursts0.10.20.5-0.20.3-0.40.40.4-0.40.6-0.40.4-0.3-0.50.70.3-0.4
Water consumed over 24 hours0.30.40.80.30.60.6-0.6-0.60.6-0.50.6-0.60.60.90.6-0.60.7
Indifference point 0 sec0.50.81.2-0.50.11.1-1.1-1.01.0-1.00.9-0.90.90.60.8-0.90.9
Indifference point AUC1.31.53.5-0.0-0.31.5-1.5-1.41.4-1.91.3-1.31.21.0-0.4-1.21.4
Indifference point function ln k2.53.55.9-0.5-0.6-2.32.32.1-2.12.4-2.12.1-1.9-1.40.11.9-2.4
Indifference point function log k2.53.55.9-0.5-0.6-2.32.32.1-2.12.4-2.12.1-1.9-1.40.11.9-2.4
Delay discounting total patch changes 0 sec0.50.81.1-0.30.51.1-1.1-1.01.0-0.91.0-1.01.00.61.0-1.01.0
Delay discounting total patch changes 12 sec5.97.810.8-0.21.33.2-3.2-3.13.1-3.33.1-3.13.02.52.0-3.03.3
Delay discounting total patch changes 18 sec0.40.61.10.40.40.9-0.9-0.90.9-1.00.8-0.80.70.3-0.1-0.81.0
Delay discounting total patch changes 24 sec6.58.210.6-1.50.43.2-3.2-3.23.2-3.13.2-3.23.12.72.5-3.02.9
Delay discounting total patch changes 6 sec0.91.42.1-0.80.01.4-1.4-1.31.3-1.51.2-1.21.30.90.6-1.31.1
Delay discounting time to switch 0 sec0.30.51.6-1.1-1.30.7-0.7-0.60.6-0.90.6-0.60.70.60.2-0.60.3
Delay discounting water rate 0 sec0.50.91.11.10.3-0.90.91.1-1.11.0-0.90.9-1.0-1.0-0.71.0-0.7
Delay discounting water rate 12 sec1.31.93.90.30.5-1.61.61.5-1.52.0-1.51.5-1.5-1.00.11.5-1.4
Delay discounting water rate 18 sec0.40.61.7-0.60.2-0.80.80.7-0.71.3-0.70.7-0.7-0.41.00.6-0.9
Delay discounting water rate 24 sec1.01.42.50.70.5-1.41.41.4-1.41.6-1.41.4-1.2-0.7-0.31.2-1.1
Delay discounting water rate 6 sec0.71.02.70.50.8-1.21.21.1-1.11.7-0.90.9-1.0-0.90.51.0-0.9
Locomotor activity0.40.72.30.51.4-0.70.70.5-0.51.2-0.50.5-0.6-1.5-0.30.5-0.5
Locomotor testing distance0.40.62.50.21.1-0.80.80.5-0.51.3-0.50.5-0.6-1.6-0.00.5-0.7
Locomotor testing rearing0.61.01.80.50.3-1.21.21.0-1.01.4-1.01.0-1.1-1.1-0.41.1-1.0
Light reinforcement 10.30.52.60.7-0.6-0.50.50.6-0.60.3-0.60.6-0.7-0.8-1.60.7-0.4
Light reinforcement 21.01.35.4-0.3-2.3-0.60.70.9-0.90.3-1.01.0-0.9-0.5-2.30.9-1.1
Reaction time number correct0.30.41.0-0.00.30.7-0.7-0.70.7-0.60.8-0.80.60.51.0-0.60.8
Reaction time mean minus median0.20.20.60.70.20.5-0.5-0.40.4-0.60.3-0.30.30.7-0.4-0.20.7
Reaction time mean minus median AUC0.20.31.81.31.00.2-0.2-0.10.1-0.20.1-0.10.00.6-0.10.00.8
Reaction time num false alarms0.20.33.10.71.8-0.20.20.0-0.00.40.0-0.00.1-0.40.8-0.00.1
Reaction time num false alarms AUC0.60.96.00.72.40.4-0.4-0.70.7-0.10.7-0.70.7-0.01.4-0.70.8
Reaction time trials correct on left0.30.41.0-0.00.30.7-0.7-0.70.7-0.60.8-0.80.60.51.0-0.60.8
Reaction time trials on left0.30.51.10.00.40.7-0.7-0.70.7-0.60.8-0.80.60.51.1-0.60.9
Reaction time mean0.20.20.70.9-0.5-0.30.30.5-0.50.0-0.40.4-0.60.3-0.60.6-0.0
Reaction time mean AUC0.40.50.80.8-0.9-0.60.60.8-0.80.2-0.70.7-0.90.1-0.80.9-0.3
Median of all reaction times0.10.10.80.3-0.9-0.10.10.3-0.3-0.2-0.20.2-0.30.4-0.20.30.0
Reaction time omissions0.20.31.61.21.30.3-0.3-0.30.3-0.30.2-0.20.30.50.3-0.30.7
Reaction time false alarm rate0.20.22.50.41.6-0.10.1-0.10.10.30.0-0.00.2-0.40.6-0.20.0
Reaction time premature initiation rate3.44.65.7-1.9-0.82.3-2.3-2.32.3-2.22.3-2.32.41.92.4-2.41.7
Reaction time premature initiations4.26.08.2-1.4-0.02.7-2.7-2.62.6-2.52.7-2.72.72.22.9-2.72.4
Std. dev. reaction times0.30.42.41.60.7-0.30.30.4-0.40.2-0.50.5-0.50.2-0.60.60.2
Reaction time trials completed0.30.51.10.00.40.7-0.7-0.70.7-0.60.8-0.80.60.51.1-0.60.9
Reaction time trials AUC0.20.41.1-0.10.30.6-0.6-0.60.6-0.50.7-0.70.50.41.0-0.50.7
Social response proportion0.10.10.2-0.5-0.40.3-0.3-0.30.3-0.30.3-0.30.2-0.20.0-0.20.2
Social responses0.10.10.70.60.80.3-0.3-0.20.2-0.20.3-0.30.1-0.10.2-0.10.5
Social time0.30.43.41.01.80.1-0.1-0.20.20.10.2-0.20.10.40.7-0.10.7
Conditioned locomotion0.70.81.2-0.30.61.0-1.0-1.01.0-0.81.0-1.01.00.60.9-1.10.9
Cocaine response after cond. corrected0.30.30.6-0.20.4-0.70.70.5-0.50.8-0.50.5-0.4-0.20.60.4-0.6
Cocaine response after cond. not corrected0.40.40.7-0.2-0.6-0.80.80.7-0.70.6-0.70.7-0.7-0.2-0.10.7-0.8
Cocaine response before conditioning0.40.54.00.3-2.00.1-0.10.2-0.2-0.7-0.20.2-0.30.2-1.60.40.0
Saline control response2.02.63.5-0.30.51.8-1.8-1.81.8-1.81.8-1.81.71.41.6-1.81.9
Condit. Reinf. active minus inactive responses0.60.71.70.7-0.9-0.80.80.9-0.90.5-0.90.9-1.0-0.5-1.30.9-0.7
Condit. Reinf. active-inactive response ratio0.70.71.4-0.0-1.2-0.80.80.9-0.90.7-0.80.8-0.9-0.2-1.20.9-0.9
Condit. Reinf. active responses0.10.10.70.2-0.8-0.20.20.3-0.30.0-0.30.3-0.40.0-0.40.4-0.2
Condit. Reinf. inactive responses0.00.00.10.1-0.30.1-0.10.0-0.0-0.2-0.00.0-0.0-0.20.30.00.2
Condit. Reinf. lever presses0.40.62.1-0.6-1.40.7-0.7-0.50.5-1.00.5-0.50.51.4-0.1-0.60.5
Condit. Reinf. lever reinforcers received0.10.10.50.3-0.70.0-0.10.1-0.1-0.3-0.10.1-0.10.4-0.20.10.2
Pavlov. Cond. lever latency0.40.52.81.11.7-0.40.40.3-0.30.7-0.30.3-0.2-1.30.20.2-0.1
Pavlov. Cond. magazine entry latency3.23.710.8-0.6-1.02.0-2.0-1.81.8-2.51.8-1.81.83.31.3-1.82.1
Pavlov. Cond. change in total contacts0.70.94.8-0.5-2.20.8-0.8-0.50.5-1.40.4-0.40.41.7-0.3-0.40.7
Pavlov. Cond. index score1.52.07.0-0.9-1.91.4-1.4-1.11.1-2.01.1-1.11.12.70.3-1.11.2
Pavlov. Cond. latency score1.51.96.5-1.1-2.01.3-1.3-1.01.0-1.91.0-1.01.12.60.3-1.11.1
Pavlov. Cond. lever contacts0.20.32.3-0.1-1.10.3-0.3-0.10.1-0.70.1-0.10.11.5-0.2-0.10.4
Pavlov. Cond. magazine entry number5.16.315.11.01.2-2.72.72.4-2.43.2-2.42.4-2.4-3.9-1.82.4-2.7
Pavlov. Cond. intertrial magazine entries1.41.94.60.90.3-1.31.31.3-1.31.5-1.31.3-1.4-2.1-1.71.4-1.3
Pavlov. Cond. lever-magazine prob. diff.1.72.27.7-0.8-2.01.5-1.5-1.21.2-2.11.2-1.21.22.80.4-1.21.4
Pavlov. Cond. response bias0.91.35.3-0.5-1.31.0-1.0-0.90.9-1.50.9-0.90.92.30.5-0.91.1
Conditioned reinforcement - actives2.02.02.80.8-0.6-1.61.61.6-1.61.3-1.71.7-1.7-1.0-1.01.6-1.3
Conditioned reinforcement - inactives1.01.22.5-0.4-1.6-1.11.11.1-1.10.8-1.11.1-1.2-0.8-0.91.1-1.3
Conditioned locomotion1.61.93.0-0.3-1.5-1.51.51.4-1.41.5-1.41.4-1.6-1.2-1.01.6-1.7
Intermittent access intake day 1-15 change1.61.63.41.4-0.2-1.21.21.4-1.41.0-1.31.3-1.5-1.1-1.81.5-0.8
Intermittent access intake escalation1.01.02.01.1-0.2-0.90.91.1-1.10.8-1.01.0-1.2-0.8-1.41.1-0.6
Intermittent access intake escalation 20.10.10.40.6-0.1-0.10.10.4-0.4-0.2-0.30.3-0.3-0.1-0.60.30.1
Intermitt. access day 1 inactive lever presses1.61.83.2-0.7-1.8-1.31.31.3-1.31.3-1.21.2-1.4-1.0-1.41.4-1.7
Intermitt. access day 15 inactive lever presses0.70.87.1-1.4-2.70.1-0.1-0.00.0-0.2-0.00.0-0.20.1-1.00.2-0.7
Intermitt. access escalation Index0.20.20.8-0.8-0.4-0.20.30.2-0.20.6-0.10.1-0.2-0.9-0.50.2-0.7
Intermittent access day 1 total infusions1.21.37.3-1.8-2.7-0.70.70.6-0.60.7-0.70.7-0.7-0.7-0.60.7-1.6
Intermittent access day 15 total infusions3.33.75.2-0.1-2.2-1.91.92.0-2.01.7-2.02.0-2.0-1.9-2.12.0-2.3
Intermittent access terminal intake (last 3 days)1.01.15.3-0.8-2.3-0.80.81.0-1.00.4-0.90.9-0.9-0.6-1.00.9-1.2
Intermittent access total infusions1.21.45.5-0.9-2.3-0.90.91.0-1.00.6-1.01.0-1.0-0.8-1.40.9-1.5
Intermittent access day 1 locomotion0.80.84.9-2.2-2.2-0.00.1-0.00.00.10.1-0.10.10.10.5-0.1-0.9
Intermittent access day 15 total locomotion0.50.54.4-1.3-2.1-0.20.20.3-0.30.1-0.20.2-0.40.3-0.00.4-0.8
Intermittent access total locomotion1.31.513.0-2.2-3.6-0.20.20.4-0.4-0.1-0.20.2-0.30.1-0.70.3-1.3
Intermittent access standard deviation1.01.11.71.20.6-1.21.21.2-1.21.0-1.21.2-1.3-0.30.11.2-0.6
Cocaine induced anxiety0.20.20.5-0.1-0.20.4-0.4-0.40.4-0.60.4-0.40.40.70.3-0.40.5
Post-drug Anxiety0.40.40.9-0.1-0.50.7-0.7-0.60.6-0.90.6-0.60.60.90.5-0.60.7
Baseline Anxiety1.01.11.9-0.20.31.1-1.1-1.11.1-1.01.1-1.11.11.01.4-1.11.1
Lifetime Intake0.80.93.3-1.0-1.8-0.90.90.8-0.80.7-0.80.8-0.8-0.7-0.50.8-1.4
Incentive Sensitization - Responses0.20.21.9-0.6-1.40.1-0.1-0.10.1-0.3-0.00.00.10.1-0.6-0.1-0.2
Incentive Sensitization - Breakpoint0.30.32.8-0.7-1.70.1-0.00.0-0.0-0.2-0.10.1-0.1-0.1-0.80.1-0.4
Progressive ratio test 1 active lever presses1.21.31.70.4-0.7-1.21.21.2-1.21.1-1.21.2-1.2-1.2-1.31.2-1.3
Progressive ratio test 1 breakpoint1.41.41.70.5-0.5-1.31.31.3-1.31.2-1.31.3-1.3-1.3-1.21.3-1.3
Progressive ratio test 1 inactive lever presses0.40.51.5-1.2-0.60.5-0.5-0.70.7-0.40.6-0.60.50.71.1-0.50.2
Progressive ratio test 2 active lever presses1.51.63.0-0.2-1.7-1.21.21.3-1.31.0-1.31.3-1.3-1.2-1.51.3-1.5
Progressive ratio test 2 breakpoint2.42.64.70.3-1.6-1.61.61.6-1.61.4-1.71.7-1.7-1.6-2.21.7-1.9
Progressive ratio test 2 inactive lever presses0.80.95.3-1.0-2.3-0.70.70.7-0.70.4-0.80.8-0.7-0.5-0.60.8-1.2
Total sessions with >9 infusions1.01.12.2-0.8-1.0-1.11.10.9-0.91.2-0.90.9-1.1-0.9-0.31.1-1.5
Short access day 1 total inactive lever presses0.60.71.5-0.7-1.0-0.80.90.8-0.80.8-0.80.8-0.7-0.9-0.30.6-1.2
Short access day 10 total inactive lever presses1.51.63.00.10.3-1.51.51.3-1.31.7-1.31.3-1.4-1.4-0.71.4-1.4
Short access day 1 total infusions0.50.61.0-0.8-0.4-0.90.90.7-0.70.8-0.70.7-0.7-0.60.70.6-1.0
Short access day 10 total infusions0.70.85.6-1.9-2.4-0.40.40.2-0.20.2-0.20.2-0.3-0.3-0.10.2-1.2
Short access total infusions0.40.42.1-1.5-1.2-0.40.40.2-0.20.4-0.30.3-0.3-0.30.80.2-0.9
Short access day 1 locomotion0.60.63.4-1.8-0.60.4-0.4-0.40.4-0.20.5-0.50.30.61.8-0.30.0
Short access day 10 total locomotion0.50.63.5-1.7-1.90.1-0.1-0.00.0-0.10.3-0.30.10.70.8-0.2-0.6
Short access total locomotion1.01.04.7-2.2-1.70.6-0.5-0.60.6-0.50.7-0.70.60.81.5-0.6-0.1
Compulsive drug intake2.02.07.20.82.71.0-1.0-1.31.3-0.71.2-1.21.31.12.1-1.21.6
One hour access (0.3 mA shock)3.33.85.60.1-1.7-2.12.12.0-2.01.9-2.12.1-2.1-1.9-2.12.1-2.4
One hour access (shock baseline)5.26.010.60.5-2.3-2.42.42.6-2.62.0-2.62.6-2.5-2.3-3.32.5-2.7
Number of responses in last shaping day0.40.42.8-0.40.90.3-0.3-0.50.5-0.10.5-0.50.30.31.7-0.30.5
Context. condit. distance diff. score0.10.10.6-0.40.0-0.40.40.2-0.20.5-0.20.2-0.40.00.70.4-0.4
Locomotion velocity, session 10.10.21.6-0.5-0.00.1-0.1-0.20.2-0.10.2-0.20.20.11.2-0.20.2
Locomotion distance, session 11.01.35.5-1.5-0.20.9-0.9-1.11.1-0.91.1-1.11.00.42.4-1.00.8
Locomotion velocity, session 22.83.34.3-1.3-0.21.9-1.9-1.91.9-2.01.9-1.92.01.72.1-2.01.7
Locomotion distance, session 20.81.14.4-0.70.90.8-0.8-1.11.1-0.61.1-1.11.00.72.1-1.00.9
Locomotion velocity, session 30.70.84.3-2.1-1.30.6-0.6-0.50.5-0.50.5-0.50.70.71.5-0.7-0.1
Locomotion distance, session 30.00.10.3-0.4-0.30.1-0.1-0.00.0-0.10.0-0.00.2-0.30.5-0.2-0.1
Stereotopy head waving bouts, day 30.30.43.1-1.8-0.60.2-0.2-0.40.40.10.4-0.40.40.01.0-0.4-0.4
Stereotopy head waving duration, day 30.20.31.5-1.20.20.2-0.2-0.40.40.20.4-0.40.40.41.0-0.4-0.1
Locomotion velocity, session 70.00.10.3-0.6-0.30.2-0.1-0.20.20.00.1-0.10.1-0.3-0.1-0.1-0.2
Locomotion distance, session 70.10.10.7-0.80.3-0.10.1-0.20.20.30.1-0.10.1-0.10.8-0.1-0.3
Stereotopy head waving bouts, day 70.10.20.4-0.5-0.60.5-0.5-0.40.4-0.50.4-0.40.40.3-0.0-0.30.3
Stereotopy head waving duration, day 71.51.92.7-0.8-0.41.6-1.6-1.51.5-1.61.5-1.51.51.10.9-1.51.4
Locomotion velocity, session 80.20.21.50.31.20.3-0.3-0.40.4-0.00.4-0.40.3-0.20.8-0.30.5
Locomotion distance, session 80.10.21.1-1.1-0.1-0.20.2-0.10.10.40.0-0.0-0.2-0.31.00.1-0.4
Degree of sensitization distance0.20.22.0-1.4-0.4-0.00.0-0.30.30.30.2-0.20.10.40.7-0.1-0.4
Degree of sensitization stereotypy0.60.71.4-0.2-0.81.0-1.0-0.80.8-1.20.8-0.80.80.80.1-0.70.9
Condit. Reinf. active minus inactive responses0.60.71.4-0.6-0.50.8-0.9-0.80.8-1.20.8-0.80.90.81.0-0.90.9
Condit. Reinf. active-inactive response ratio0.30.40.80.30.50.5-0.5-0.50.5-0.70.5-0.50.60.80.9-0.60.9
Condit. Reinf. active responses0.60.81.7-1.2-1.30.8-0.8-0.70.7-1.20.6-0.60.80.81.0-0.80.6
Condit. Reinf. inactive responses0.40.43.1-1.3-1.7-0.30.30.4-0.40.0-0.40.4-0.3-0.20.10.3-0.7
Incentive salience index mean0.81.01.8-1.3-1.31.0-1.0-0.90.9-1.30.9-0.91.00.41.0-1.00.7
Condit. Reinf. lever presses0.50.73.4-1.5-1.80.7-0.7-0.60.6-1.00.6-0.60.7-0.20.4-0.70.2
Time in familiar zone, hab. session 10.10.10.7-0.5-0.80.0-0.00.1-0.1-0.2-0.10.1-0.10.20.20.1-0.0
Time in novel zone, hab. session 11.11.11.60.70.5-1.21.21.1-1.11.2-1.11.1-1.1-0.9-0.71.1-1.0
Total zone transitions, hab. session 10.40.60.90.10.90.8-0.8-0.80.8-0.60.8-0.80.80.10.9-0.80.9
Total locomotion distance, hab. session 10.10.10.8-0.9-0.6-0.10.10.0-0.00.1-0.10.1-0.0-0.10.30.1-0.3
Locomotion velocity, hab. session 10.20.30.6-0.7-0.10.5-0.5-0.60.6-0.50.6-0.60.60.30.8-0.60.4
Time in familiar zone, hab. session 20.80.81.11.00.1-0.90.91.0-1.00.8-1.01.0-1.0-0.7-1.11.0-0.6
Time in novel zone, hab. session 20.90.91.9-1.1-0.20.9-0.9-1.01.0-0.81.0-1.01.00.71.4-1.00.7
Total zone transitions, hab. session 21.21.64.6-1.1-0.31.3-1.3-1.31.3-1.41.2-1.21.30.52.2-1.31.1
Total locomotion distance, hab. session 20.30.42.5-1.1-0.60.3-0.3-0.30.3-0.40.3-0.30.40.31.6-0.40.1
Locomotion velocity, hab. session 20.20.31.5-1.1-0.80.1-0.1-0.10.1-0.30.1-0.10.30.11.2-0.3-0.1
Novel to familiar place preference ratio2.32.43.2-1.00.51.7-1.7-1.81.8-1.51.7-1.71.81.11.5-1.81.5
Novelty place preference1.41.52.0-0.80.51.3-1.3-1.41.4-1.11.4-1.41.40.91.3-1.41.1
Time in novel zone, NPP test1.61.72.4-0.90.61.4-1.4-1.51.5-1.11.5-1.51.51.21.5-1.51.2
Total zone transitions, NPP test1.42.13.7-0.50.71.5-1.5-1.61.6-1.51.6-1.61.50.71.9-1.51.6
Total locomotion distance, NPP test0.30.41.3-0.70.20.5-0.5-0.60.6-0.50.6-0.60.70.31.1-0.70.4
Locomotion velocity, NPP test0.10.20.4-0.30.40.4-0.4-0.50.5-0.40.5-0.50.6-0.00.6-0.60.4
Pavlov. Cond. lever latency0.81.02.11.31.4-1.11.10.9-0.91.3-0.90.9-1.0-0.1-0.81.0-0.6
Pavlov. Cond. magazine entry latency0.60.73.3-1.0-1.80.9-0.9-0.60.6-1.20.6-0.60.60.60.3-0.60.5
Pavlov. Cond. change in total contacts0.20.22.2-0.3-1.50.3-0.3-0.10.1-0.70.1-0.10.10.1-0.5-0.10.1
Pavlov. Cond. index score0.30.31.6-0.4-1.30.6-0.6-0.40.4-1.00.4-0.40.40.1-0.1-0.40.4
Pavlov. Cond. latency score0.30.32.1-0.7-1.50.5-0.5-0.30.3-0.90.3-0.30.4-0.10.1-0.40.2
Pavlov. Cond. lever contacts0.20.21.6-0.7-1.30.4-0.4-0.20.2-0.50.2-0.20.3-0.4-0.0-0.30.0
Pavlov. Cond. magazine entry number0.30.31.1-0.21.0-0.70.70.4-0.41.1-0.40.4-0.4-0.40.20.4-0.7
Pavlov. Cond. intertrial magazine entries0.20.21.10.90.50.2-0.2-0.10.1-0.30.1-0.10.2-0.7-1.0-0.20.4
Pavlov. Cond. lever-magazine prob. diff.0.30.41.2-0.4-1.10.8-0.8-0.50.5-1.10.6-0.60.60.30.1-0.60.6
Pavlov. Cond. response bias0.30.41.6-0.3-1.30.7-0.7-0.40.4-1.00.4-0.40.50.3-0.2-0.50.5
Bone: apparent density0.20.31.6-1.1-1.30.4-0.4-0.40.4-0.60.4-0.40.3-0.2-0.2-0.4-0.0
Bone surface1.01.83.8-1.5-1.91.5-1.5-1.31.3-1.81.3-1.31.30.3-0.2-1.30.8
Bone volume0.50.84.1-1.3-2.00.8-0.8-0.60.6-1.10.6-0.60.50.0-0.7-0.60.2
Bone: connectivity density1.11.72.7-1.6-1.21.5-1.5-1.41.4-1.71.4-1.41.40.50.9-1.41.0
Bone: cortical apparent density0.40.51.00.70.50.8-0.8-0.80.8-0.90.8-0.80.70.40.3-0.71.0
Bone: cortical area0.40.61.7-0.6-1.30.9-0.9-0.70.7-1.10.6-0.60.70.4-0.1-0.70.6
Bone: cortical porosity0.20.21.41.01.20.1-0.1-0.10.10.10.1-0.10.0-0.00.2-0.00.4
Bone: cortical porosity0.40.52.41.01.60.5-0.5-0.50.5-0.20.6-0.60.40.30.5-0.40.8
Bone: cortical thickness2.44.06.40.51.02.3-2.3-2.12.1-2.32.1-2.12.21.51.6-2.22.5
Bone: cortical thickness0.40.50.90.60.80.7-0.7-0.60.6-0.80.6-0.60.80.70.6-0.81.0
Bone: cortical tissue density0.60.71.30.80.70.9-0.9-0.90.9-1.00.9-0.90.80.50.4-0.81.2
Bone: elastic displacement0.40.52.11.21.5-0.70.70.4-0.40.8-0.50.5-0.6-0.70.10.6-0.2
Bone: elastic work1.01.32.90.31.51.0-1.0-1.11.1-0.91.1-1.11.20.41.7-1.21.4
Bone: endosteal estimation1.63.57.7-2.0-2.8-1.71.71.7-1.71.6-1.81.8-1.7-1.4-1.41.7-2.5
Bone: endosteal perimeter2.75.511.7-1.8-3.4-2.12.22.3-2.31.9-2.42.4-2.2-1.6-2.52.2-3.0
Bone: final force1.32.13.6-1.3-1.11.6-1.6-1.51.5-1.91.4-1.41.51.21.2-1.61.3
Bone: final moment1.22.03.4-1.3-1.11.5-1.5-1.41.4-1.81.4-1.41.51.11.1-1.51.2
Bone: marrow area1.73.77.2-1.9-2.7-1.81.81.8-1.81.7-1.91.9-1.8-1.5-1.51.8-2.6
Bone: maximum diameter0.20.43.3-1.0-1.80.3-0.3-0.00.0-0.5-0.00.00.10.2-0.7-0.1-0.2
Bone: maximum force1.73.05.8-2.4-2.31.8-1.8-1.71.7-2.11.6-1.61.71.21.0-1.71.1
Bone: maximum moment1.62.85.2-2.3-2.11.8-1.8-1.61.6-2.01.6-1.61.61.20.9-1.61.1
Bone: minimum diameter1.32.48.6-1.8-2.9-1.21.21.3-1.31.1-1.41.4-1.4-1.2-1.41.4-2.0
Bone: periosteal estimation0.51.06.6-1.6-2.6-0.40.40.6-0.60.2-0.70.7-0.5-0.5-1.00.5-1.1
Bone: periosteal perimeter0.40.64.3-1.0-2.1-0.30.30.5-0.50.1-0.60.6-0.5-0.3-1.00.5-0.8
Bone: post-yield work1.72.313.9-2.2-3.7-0.60.60.9-0.90.4-0.90.9-0.9-1.1-1.71.0-1.7
Bone: stiffness0.40.62.7-1.0-1.60.8-0.8-0.50.5-1.10.5-0.50.60.6-0.2-0.60.4
Bone: tissue strength0.60.61.40.2-0.3-0.80.80.8-0.80.6-0.80.8-0.8-1.2-0.80.8-0.8
Bone: trabecular number0.50.71.9-1.4-1.20.8-0.8-0.80.8-1.00.8-0.80.80.40.3-0.80.4
Bone: trabecular spacing0.30.41.61.21.0-0.70.60.6-0.60.6-0.60.6-0.6-0.10.30.6-0.1
Bone: trabecular thickness0.70.82.7-0.2-1.1-0.70.70.8-0.80.6-0.80.8-0.8-0.8-1.70.9-1.0
Bone: trabecular tissue density3.24.55.61.40.3-2.32.32.3-2.32.3-2.42.4-2.3-2.2-1.92.3-2.0
Breakpoint value in progressive ratio session1.92.13.80.31.01.5-1.6-1.41.4-1.61.4-1.41.31.81.4-1.32.0
Distance traveled before self-admin1.31.42.7-0.5-0.81.4-1.4-1.21.2-1.61.3-1.31.11.30.1-1.11.3
Distance traveled after self-admin0.10.20.80.2-0.50.4-0.4-0.30.3-0.30.3-0.30.00.3-0.9-0.00.3
Delta time in closed arm before/after self-admin4.34.114.5-1.62.11.7-1.7-2.12.1-1.02.1-2.11.81.53.8-1.81.8
Delta time in open arm before/after self-admin0.90.92.30.3-0.61.0-1.0-0.70.7-1.50.7-0.70.91.5-0.3-0.91.1
Diff in mean of infusions in LGA sessions1.92.23.50.51.51.5-1.5-1.31.3-1.51.4-1.41.51.61.8-1.51.9
Extinction: sum of active levers before priming2.82.83.8-0.80.11.9-1.9-1.71.7-2.01.7-1.71.71.91.7-1.71.9
Active lever presses in extinction session 61.51.53.30.20.01.4-1.4-1.11.1-1.81.1-1.11.21.60.5-1.21.7
Delta distance traveled before/after self-admin0.50.61.10.50.5-0.90.90.8-0.81.1-0.80.8-0.8-0.6-0.20.8-0.8
Delta ambulatory time before/after self-admin0.70.81.70.61.0-1.01.00.9-0.91.3-0.80.8-0.9-0.9-0.20.9-0.8
Time in closed arm before self-admin0.40.52.60.1-1.4-0.20.20.5-0.50.1-0.40.4-0.5-0.4-1.60.5-0.5
Time in closed arm after self-admin0.20.20.8-0.40.5-0.40.50.3-0.30.9-0.20.2-0.5-0.70.30.5-0.4
Time in open arm before self-admin0.60.74.10.42.0-0.70.70.3-0.31.1-0.40.4-0.3-0.91.20.3-0.4
Time in open arm after self-admin0.30.42.11.51.40.1-0.10.0-0.0-0.3-0.10.10.30.40.1-0.30.6
Sum of active levers in priming session hrs 5-60.50.51.40.9-0.20.8-0.8-0.50.5-1.20.4-0.40.51.1-0.0-0.51.1
Time to tail flick, vehicle, before self-admin0.70.72.4-1.5-1.20.7-0.7-0.70.7-0.80.6-0.60.80.50.9-0.80.2
Time to tail flick, vehicle, after self-admin0.80.82.6-1.0-0.10.8-0.8-1.01.0-0.61.1-1.10.80.71.6-0.80.6
Time to tail flick, test, before self-admin0.40.41.5-1.2-0.10.5-0.5-0.60.6-0.30.8-0.80.90.00.5-0.9-0.0
Time to tail flick, test, after self-admin0.20.21.40.70.4-0.30.30.3-0.30.3-0.40.4-0.3-0.5-1.20.3-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.20.20.50.1-0.2-0.30.30.00.3-0.30.10.00.4-0.10.3
Delta time to tail flick, test, before/after SA0.40.32.51.60.9-0.20.20.3-0.30.0-0.50.5-0.40.3-0.50.40.5
Ambulatory time before self-admin1.01.02.6-0.2-1.01.2-1.2-0.80.8-1.60.9-0.90.91.2-0.5-0.91.1
Ambulatory time after self-admin0.40.43.3-0.5-1.80.2-0.2-0.00.0-0.30.1-0.1-0.20.2-1.40.2-0.1
Total heroin consumption3.84.57.30.41.92.2-2.2-2.12.1-2.22.0-2.02.12.22.6-2.12.7
Area under the delay curve0.20.21.3-1.1-0.40.4-0.4-0.50.5-0.10.5-0.50.3-0.50.1-0.3-0.1
Delay disc. indifference point, 0s delay0.30.32.6-1.6-0.6-0.10.1-0.20.20.50.2-0.2-0.1-0.50.50.0-0.6
Delay disc. indifference point, 16s delay0.20.20.9-0.8-1.00.3-0.3-0.20.2-0.30.2-0.20.2-0.1-0.3-0.1-0.1
Delay disc. indifference point, 2s delay0.50.52.4-1.2-1.5-0.30.30.3-0.30.4-0.30.3-0.5-1.0-0.80.4-0.9
Delay disc. indifference point, 24s delay0.10.10.2-0.40.20.4-0.4-0.50.5-0.20.5-0.50.4-0.10.1-0.50.2
Delay disc. indifference point, 4s delay0.91.02.3-1.50.20.9-0.9-1.11.1-0.51.1-1.11.1-0.11.3-1.10.4
Delay disc. indifference point, 8s delay0.20.21.1-0.30.8-0.10.1-0.10.10.60.1-0.1-0.0-1.0-0.00.1-0.3
Delay discount exponential model param0.20.21.21.10.4-0.40.40.5-0.50.1-0.50.5-0.30.5-0.00.30.1
Delay discount hyperbolic model param0.20.31.51.20.5-0.40.40.5-0.50.1-0.50.5-0.40.5-0.10.40.1
Fecal boli incidents, locomotor time 10.70.72.50.6-1.1-0.70.70.9-0.90.3-0.90.9-1.00.1-1.61.0-0.6
Change in fecal boli incidents, locomotor task0.40.41.3-1.00.3-0.50.60.2-0.20.9-0.30.3-0.1-1.10.90.1-0.9
Time >=10cm from walls, locomotor time 12.92.94.7-0.0-1.9-1.71.71.9-1.91.4-1.81.8-1.8-0.9-2.21.8-1.9
Bouts of movement, locomotor time 10.70.83.51.71.90.5-0.5-0.40.4-0.60.3-0.30.31.20.3-0.31.3
Total resting periods, locomotor time 10.40.52.01.41.10.5-0.5-0.30.3-0.60.3-0.30.20.9-0.2-0.21.1
Rest time, locomotor task time 11.31.42.31.10.6-1.21.21.1-1.11.4-1.21.2-1.3-1.2-1.51.3-1.0
Distance moved, locomotor task time 10.30.30.9-1.0-0.80.4-0.4-0.40.4-0.60.5-0.50.40.70.9-0.40.3
Vertical activity count, locomotor time 10.50.50.80.0-0.1-0.80.80.9-0.90.8-0.70.7-0.8-0.6-0.40.8-0.8
Time >=10cm from walls, locomotor time 20.60.62.70.8-0.7-0.60.60.8-0.80.2-0.80.8-0.7-0.3-1.60.7-0.5
Bouts of movement, locomotor time 21.51.64.5-0.00.91.0-1.1-1.11.1-1.30.9-0.91.12.12.1-1.11.6
Total resting periods, locomotor time 20.91.03.80.00.90.7-0.7-0.80.8-0.90.5-0.50.71.81.9-0.71.2
Rest time, locomotor task time 22.22.64.50.70.6-1.91.91.6-1.62.1-1.71.7-1.9-1.3-0.71.9-1.7
Distance moved, locomotor task time 20.30.40.70.50.00.7-0.7-0.50.5-0.90.6-0.60.60.6-0.4-0.60.8
Vertical activity count, locomotor time 20.30.32.61.21.6-0.00.00.1-0.10.10.2-0.20.1-0.1-0.3-0.10.4
Weight adjusted by age1.71.95.0-1.0-0.31.2-1.2-1.31.3-1.41.4-1.41.12.21.8-1.11.4
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.4-0.20.1-0.1-0.10.1-0.00.2-0.20.2-0.10.2-0.1-0.1
Locomotion in novel chamber2.83.57.3-0.2-2.1-1.71.71.8-1.81.5-1.81.8-2.0-1.8-2.72.1-2.1
Locomotion in novel chamber post-restriction1.61.93.11.21.1-1.51.51.3-1.31.8-1.51.5-1.5-1.0-0.91.6-1.1
Progressive ratio0.10.11.1-0.3-1.1-0.20.20.2-0.20.1-0.20.2-0.30.1-0.30.3-0.4
Food seeking constrained by brief footshock0.10.10.20.00.5-0.30.30.1-0.10.5-0.20.2-0.20.10.30.3-0.1
Seeking ratio, punishment vs. effort0.20.21.90.01.40.0-0.0-0.30.30.20.2-0.20.30.11.0-0.30.3
Run reversals in cocaine runway, females1.01.02.4-1.5-0.40.9-0.9-1.01.0-0.81.0-1.01.20.51.2-1.20.4
Run reversals in cocaine runway, males0.80.72.40.60.4-0.60.60.7-0.70.8-0.80.8-0.6-1.5-1.50.6-0.7
Latency to leave start box in cocaine runway0.70.73.2-0.9-1.8-0.50.50.5-0.50.6-0.60.6-0.6-0.9-1.10.5-1.2
Latency to leave start box in cocaine runway, F0.10.21.3-0.5-1.10.2-0.2-0.10.1-0.10.2-0.20.1-0.3-0.5-0.1-0.3
Latency to leave start box in cocaine runway, M2.92.84.10.0-0.8-1.81.81.7-1.71.8-1.81.8-1.8-1.8-1.71.7-2.0
Cd content in liver1.31.42.10.4-0.7-1.21.21.3-1.31.1-1.31.3-1.3-1.5-1.31.4-1.1
Co content in liver1.82.14.52.11.4-1.51.51.5-1.51.5-1.51.5-1.5-0.9-1.21.5-0.8
Cu content in liver0.60.71.70.11.20.6-0.6-0.90.9-0.40.9-0.90.80.61.3-0.80.8
Fe content in liver0.00.00.2-0.00.10.0-0.0-0.10.1-0.10.1-0.10.10.10.5-0.10.1
K content in liver0.80.81.9-1.4-1.41.0-0.9-0.80.8-0.90.9-0.90.80.10.4-0.80.3
Mg content in liver0.60.63.0-1.7-1.60.5-0.5-0.50.5-0.50.6-0.60.4-0.20.7-0.4-0.1
Mn content in liver1.41.62.3-0.6-0.21.5-1.5-1.41.4-1.51.5-1.51.41.00.8-1.41.2
Na content in liver0.30.41.1-0.5-1.00.6-0.6-0.50.5-0.90.6-0.60.50.3-0.0-0.50.5
Rb content in liver1.21.52.4-0.3-0.5-1.41.41.3-1.31.5-1.31.3-1.3-1.1-0.51.3-1.5
Se content in liver0.20.20.6-0.4-0.40.6-0.6-0.50.5-0.40.6-0.60.40.80.2-0.30.4
Sr content in liver5.85.37.2-0.21.02.5-2.5-2.52.5-2.42.6-2.62.52.42.1-2.42.7
Zn content in liver3.64.05.8-0.9-0.32.2-2.2-2.12.1-2.42.3-2.32.21.42.0-2.22.1