RT1-S2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000032664 0.5 0.1 0.0e+00 0.58 0.47 0.6 0.61 5.9e-78 2.1e-58 3.2e-84 1.1e-85
2 BLA gene expression ENSRNOG00000032664 0.74 0.07 0.0e+00 0.57 0.62 0.62 0.63 2.3e-36 4.8e-41 2.7e-41 4.5e-43
3 Brain gene expression ENSRNOG00000032664 0.5 0.04 0.0e+00 0.63 0.7 0.7 0.71 2.1e-74 1.9e-91 9.9e-91 4.0e-92
4 Eye gene expression ENSRNOG00000032664 0.5 0.16 2.3e-05 0.15 0.07 0.05 0.12 2.8e-03 3.4e-02 5.5e-02 6.9e-03
5 IL gene expression ENSRNOG00000032664 0.96 0.05 0.0e+00 0.51 0.49 0.47 0.49 3.7e-14 1.7e-13 6.4e-13 1.7e-13
6 LHb gene expression ENSRNOG00000032664 0.97 0.03 0.0e+00 0.53 0.54 0.59 0.45 6.3e-15 4.7e-15 3.5e-17 3.3e-12
7 Liver gene expression ENSRNOG00000032664 0.07 0.05 1.1e-07 0.06 0.06 0.06 0.06 4.0e-07 5.6e-07 4.7e-07 9.1e-07
8 NAcc gene expression ENSRNOG00000032664 0.63 0.09 0.0e+00 0.6 0.32 0.64 0.39 1.4e-54 5.6e-24 3.2e-61 4.4e-31
9 OFC gene expression ENSRNOG00000032664 0.8 0.1 0.0e+00 0.35 0.44 0.41 0.38 3.2e-09 1.1e-11 5.9e-11 5.9e-10
10 PL gene expression ENSRNOG00000032664 0.78 0.07 0.0e+00 0.68 0.13 0.74 0.01 1.6e-69 6.3e-10 7.1e-82 7.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail2.27.18.22.62.92.72.52.62.7-2.62.82.62.7
BMI without tail4.18.59.63.02.93.02.42.92.8-3.13.03.03.0
Body weight7.230.434.45.55.55.94.45.75.2-5.75.65.85.8
Epididymis fat weight2.55.817.12.22.91.64.11.43.2-1.42.51.61.5
Glucose1.11.76.3-1.1-1.5-0.7-2.5-0.6-1.80.4-1.3-0.7-0.7
Heart weight0.10.10.30.20.30.40.10.50.3-0.30.40.40.4
Left kidney weight4.412.614.23.53.53.73.03.83.4-3.63.73.73.7
Right kidney weight3.610.312.83.13.03.52.43.62.8-3.43.33.43.5
Tail length4.313.117.23.63.34.11.74.22.9-4.03.54.14.1
Length with tail4.416.320.64.03.84.52.44.53.4-4.34.04.44.4
Length without tail3.57.69.52.72.73.12.03.12.4-2.82.82.92.9
Liver weight, left0.40.61.10.70.50.9-0.00.90.4-1.10.60.90.9
Liver weight, right2.84.66.52.11.82.50.72.51.5-2.52.02.52.5
Parametrial fat weight2.65.15.82.42.32.32.02.22.3-2.22.32.22.2
Retroperitoneal fat weight0.51.51.81.31.21.21.31.21.3-1.31.21.21.2
Intraocular pressure1.11.52.1-1.2-1.2-1.3-1.2-1.2-1.21.5-1.1-1.2-1.2
Extensor digitorum longus weight0.00.10.30.20.00.3-0.50.3-0.1-0.50.10.30.4
Soleus weight0.20.51.10.4-0.00.8-0.80.9-0.3-1.00.20.80.9
Tibialis anterior weight0.00.10.30.20.40.00.4-0.10.50.00.3-0.00.0
Tibia length2.36.48.62.42.32.91.52.91.9-2.82.52.82.9
Number of licking bursts0.40.41.7-0.6-0.7-0.5-1.3-0.4-0.80.4-0.6-0.5-0.5
Food consumed during 24 hour testing period0.70.81.30.90.71.10.61.10.6-1.10.81.01.0
Times rat made contact with spout1.01.21.8-1.0-0.9-1.3-0.1-1.4-0.71.3-1.0-1.3-1.2
Mean time between licks in bursts0.30.42.4-0.5-0.7-0.1-1.5-0.0-1.00.1-0.6-0.2-0.2
Mean num. licks in bursts0.20.21.40.00.2-0.21.2-0.30.40.30.1-0.2-0.2
Std. dev. time between licks in bursts0.30.32.4-0.1-0.30.3-1.60.3-0.5-0.4-0.20.20.2
Water consumed over 24 hours0.00.00.00.0-0.10.0-0.20.1-0.1-0.1-0.00.00.0
Indifference point 0 sec0.50.82.60.90.90.51.60.41.1-0.70.70.60.5
Indifference point AUC2.73.13.81.71.81.91.51.91.6-1.71.81.81.8
Indifference point function ln k0.50.71.3-0.9-0.9-0.7-1.1-0.6-1.00.8-0.8-0.8-0.7
Indifference point function log k0.50.71.3-0.9-0.9-0.7-1.1-0.6-1.00.8-0.8-0.8-0.7
Delay discounting total patch changes 0 sec0.71.13.61.01.20.71.90.61.4-0.91.00.80.7
Delay discounting total patch changes 12 sec1.01.33.51.11.30.91.90.81.4-0.91.10.90.8
Delay discounting total patch changes 18 sec0.40.52.70.50.80.11.6-0.00.9-0.30.50.10.1
Delay discounting total patch changes 24 sec0.40.51.3-0.3-0.3-0.91.0-1.10.10.6-0.6-0.8-0.9
Delay discounting total patch changes 6 sec0.71.13.81.01.20.62.00.51.4-0.71.00.60.6
Delay discounting time to switch 0 sec0.20.30.7-0.4-0.5-0.70.1-0.8-0.20.4-0.5-0.7-0.7
Delay discounting water rate 0 sec0.40.70.90.70.90.90.70.90.8-0.50.90.90.9
Delay discounting water rate 12 sec0.10.10.3-0.3-0.2-0.40.1-0.4-0.00.6-0.2-0.3-0.2
Delay discounting water rate 18 sec0.20.30.40.60.50.60.40.50.5-0.50.50.60.6
Delay discounting water rate 24 sec1.92.63.21.51.71.71.51.81.6-1.41.81.61.7
Delay discounting water rate 6 sec0.00.00.10.00.20.00.2-0.10.20.30.10.00.1
Locomotor activity0.81.32.71.10.71.3-0.11.40.6-1.60.91.41.3
Locomotor testing distance0.10.20.50.40.10.4-0.20.40.1-0.70.30.40.4
Locomotor testing rearing0.40.61.30.80.60.90.11.00.4-1.10.70.90.9
Light reinforcement 10.10.20.40.30.50.20.60.20.6-0.20.40.30.3
Light reinforcement 20.60.81.10.80.91.00.51.10.8-1.10.81.01.0
Reaction time number correct0.10.20.80.30.50.20.90.10.60.10.50.10.2
Reaction time mean minus median0.40.52.5-0.6-0.9-0.1-1.6-0.1-1.0-0.1-0.7-0.1-0.2
Reaction time mean minus median AUC0.50.62.3-0.8-1.0-0.4-1.5-0.3-1.10.3-0.8-0.3-0.4
Reaction time num false alarms0.40.50.70.60.80.80.30.80.6-0.60.70.80.8
Reaction time num false alarms AUC0.60.91.10.91.01.00.51.10.8-0.90.91.11.0
Reaction time trials correct on left0.10.20.80.30.50.20.90.10.60.10.50.10.2
Reaction time trials on left0.10.20.80.30.50.20.90.20.60.00.50.20.2
Reaction time mean0.81.13.8-1.0-1.2-0.6-1.9-0.5-1.40.5-1.1-0.6-0.6
Reaction time mean AUC0.81.13.8-1.0-1.2-0.6-1.9-0.5-1.40.5-1.1-0.5-0.6
Median of all reaction times0.60.92.8-0.9-1.1-0.6-1.7-0.5-1.20.6-1.0-0.6-0.6
Reaction time omissions0.50.62.4-0.7-1.0-0.4-1.5-0.3-1.10.2-0.8-0.4-0.3
Reaction time false alarm rate0.30.40.70.50.50.7-0.10.80.3-0.70.50.80.7
Reaction time premature initiation rate1.52.12.21.51.41.51.51.41.5-1.41.41.41.4
Reaction time premature initiations2.02.84.01.71.71.62.01.61.8-1.41.71.51.6
Std. dev. reaction times0.30.52.4-0.5-0.8-0.0-1.50.0-1.0-0.2-0.60.0-0.0
Reaction time trials completed0.10.20.80.30.50.20.90.20.60.00.50.20.2
Reaction time trials AUC0.10.10.70.20.50.10.80.10.50.10.40.10.1
Social response proportion0.00.00.10.1-0.10.3-0.20.3-0.0-0.30.10.30.2
Social responses0.10.20.30.30.40.50.30.50.4-0.40.50.50.5
Social time0.20.21.0-0.0-0.40.3-1.00.3-0.5-0.6-0.20.30.2
Conditioned locomotion0.70.81.10.90.81.00.61.00.7-1.00.81.00.9
Cocaine response after cond. corrected0.50.60.7-0.8-0.8-0.8-0.3-0.8-0.70.8-0.8-0.8-0.8
Cocaine response after cond. not corrected0.10.10.20.20.10.40.10.40.1-0.40.20.40.4
Cocaine response before conditioning4.75.77.52.32.22.71.42.72.0-2.72.42.62.6
Saline control response1.21.62.41.41.51.21.21.11.6-1.11.41.21.2
Condit. Reinf. active minus inactive responses1.31.72.11.31.31.40.51.51.2-1.41.41.41.4
Condit. Reinf. active-inactive response ratio2.82.93.81.71.71.90.82.01.5-1.91.71.91.8
Condit. Reinf. active responses0.00.00.1-0.0-0.0-0.0-0.30.0-0.10.00.00.00.0
Condit. Reinf. inactive responses1.82.22.5-1.5-1.5-1.6-1.0-1.6-1.41.6-1.5-1.6-1.5
Condit. Reinf. lever presses0.50.71.6-0.8-0.8-0.8-1.3-0.8-0.70.9-0.8-0.8-0.8
Condit. Reinf. lever reinforcers received0.10.10.4-0.3-0.2-0.2-0.6-0.1-0.30.2-0.2-0.2-0.2
Pavlov. Cond. lever latency0.30.40.90.60.50.61.00.60.5-0.70.50.60.6
Pavlov. Cond. magazine entry latency0.60.70.90.80.80.9-0.10.90.7-1.00.80.90.9
Pavlov. Cond. change in total contacts0.20.30.40.50.60.50.00.40.6-0.40.60.50.5
Pavlov. Cond. index score0.00.00.40.10.10.1-0.60.10.1-0.10.10.10.1
Pavlov. Cond. latency score0.10.10.20.30.30.3-0.40.30.3-0.30.30.30.3
Pavlov. Cond. lever contacts0.10.10.3-0.3-0.1-0.4-0.5-0.4-0.10.5-0.2-0.4-0.3
Pavlov. Cond. magazine entry number0.40.40.5-0.7-0.7-0.7-0.2-0.7-0.70.7-0.7-0.7-0.7
Pavlov. Cond. intertrial magazine entries1.52.03.0-1.5-1.6-1.3-1.1-1.2-1.71.3-1.6-1.3-1.3
Pavlov. Cond. lever-magazine prob. diff.0.00.10.40.10.10.1-0.60.10.1-0.10.10.10.1
Pavlov. Cond. response bias0.10.10.7-0.2-0.2-0.3-0.9-0.3-0.20.3-0.2-0.3-0.2
Conditioned reinforcement - actives0.50.50.70.80.50.60.80.60.8-0.90.60.60.6
Conditioned reinforcement - inactives1.51.73.41.41.31.11.81.11.5-1.51.21.10.9
Conditioned locomotion0.00.00.10.1-0.10.10.10.10.1-0.30.00.10.1
Intermittent access intake day 1-15 change0.80.81.00.90.90.90.71.00.9-1.01.00.90.9
Intermittent access intake escalation0.30.30.50.40.50.60.10.70.4-0.70.50.60.6
Intermittent access intake escalation 20.20.21.0-0.2-0.10.1-1.00.2-0.4-0.3-0.00.20.3
Intermitt. access day 1 inactive lever presses0.10.10.20.20.20.5-0.10.50.1-0.30.30.40.4
Intermitt. access day 15 inactive lever presses2.83.13.51.71.81.91.71.81.7-1.61.91.81.7
Intermitt. access escalation Index3.93.53.8-1.9-2.0-1.9-1.5-1.9-1.91.9-1.9-1.9-1.8
Intermittent access day 1 total infusions0.50.60.9-0.6-0.8-0.9-0.1-0.9-0.50.7-0.8-0.8-0.9
Intermittent access day 15 total infusions0.10.10.1-0.1-0.3-0.30.1-0.3-0.10.1-0.3-0.3-0.3
Intermittent access terminal intake (last 3 days)0.10.10.30.30.20.20.50.10.4-0.30.20.20.1
Intermittent access total infusions0.00.00.10.0-0.1-0.20.3-0.20.10.0-0.1-0.2-0.2
Intermittent access day 1 locomotion0.20.30.5-0.4-0.7-0.5-0.2-0.6-0.50.1-0.7-0.5-0.6
Intermittent access day 15 total locomotion0.80.81.10.90.71.10.41.10.8-1.10.81.01.0
Intermittent access total locomotion0.40.40.60.70.60.80.30.70.6-0.80.60.80.7
Intermittent access standard deviation3.03.23.71.71.91.81.81.71.9-1.71.91.71.7
Cocaine induced anxiety3.03.44.8-1.9-2.0-1.7-2.2-1.7-2.11.6-2.0-1.7-1.7
Post-drug Anxiety1.11.32.1-1.2-1.2-1.0-1.4-1.0-1.31.1-1.1-1.0-0.9
Baseline Anxiety0.10.10.30.20.40.20.50.10.4-0.10.40.10.2
Lifetime Intake0.00.00.10.1-0.1-0.10.3-0.10.1-0.0-0.1-0.1-0.2
Incentive Sensitization - Responses0.70.71.1-0.9-0.8-0.8-0.7-0.9-0.71.0-0.8-0.9-0.9
Incentive Sensitization - Breakpoint0.90.91.4-1.0-0.9-0.9-0.8-0.9-0.91.2-0.9-1.0-1.0
Progressive ratio test 1 active lever presses0.20.20.4-0.2-0.5-0.50.1-0.5-0.30.4-0.5-0.5-0.6
Progressive ratio test 1 breakpoint0.20.20.4-0.2-0.5-0.50.2-0.5-0.20.4-0.5-0.5-0.6
Progressive ratio test 1 inactive lever presses0.10.10.40.10.2-0.10.6-0.20.30.00.1-0.2-0.2
Progressive ratio test 2 active lever presses0.70.71.0-0.8-0.9-0.9-0.4-0.9-0.61.0-0.8-0.9-1.0
Progressive ratio test 2 breakpoint1.11.21.6-1.0-1.1-1.2-0.6-1.2-0.91.3-1.1-1.2-1.3
Progressive ratio test 2 inactive lever presses0.30.40.50.70.50.60.60.60.6-0.70.50.60.5
Total sessions with >9 infusions0.10.10.30.40.10.20.50.20.3-0.40.10.20.1
Short access day 1 total inactive lever presses0.10.10.20.0-0.00.3-0.40.3-0.2-0.40.00.30.3
Short access day 10 total inactive lever presses0.00.00.1-0.2-0.00.1-0.30.1-0.2-0.10.00.10.2
Short access day 1 total infusions0.40.40.6-0.6-0.7-0.7-0.4-0.7-0.50.5-0.7-0.7-0.7
Short access day 10 total infusions0.10.10.30.40.20.30.50.30.5-0.40.20.30.2
Short access total infusions0.10.10.20.40.10.20.50.20.4-0.40.20.20.2
Short access day 1 locomotion3.94.14.5-2.0-2.0-2.1-1.9-2.1-1.92.0-2.1-2.0-2.0
Short access day 10 total locomotion0.10.10.5-0.1-0.00.2-0.70.3-0.2-0.00.00.30.3
Short access total locomotion0.20.20.3-0.4-0.6-0.4-0.6-0.4-0.40.4-0.5-0.4-0.4
Compulsive drug intake4.03.94.7-2.0-2.2-2.0-1.9-2.0-2.01.9-2.1-2.0-1.9
One hour access (0.3 mA shock)0.70.81.2-0.8-1.1-1.0-0.5-1.0-0.80.7-1.0-0.9-1.0
One hour access (shock baseline)0.50.60.80.80.70.80.80.80.8-0.90.70.90.7
Number of responses in last shaping day0.20.20.50.50.30.40.30.40.5-0.70.40.50.4
Context. condit. distance diff. score7.08.512.3-2.9-3.2-2.6-3.5-2.6-3.32.6-3.0-2.7-2.7
Locomotion velocity, session 10.20.20.4-0.4-0.6-0.4-0.5-0.3-0.60.4-0.5-0.4-0.4
Locomotion distance, session 10.30.40.6-0.5-0.5-0.8-0.1-0.7-0.30.8-0.5-0.7-0.7
Locomotion velocity, session 20.00.00.0-0.0-0.10.0-0.10.1-0.2-0.0-0.10.0-0.0
Locomotion distance, session 20.30.40.6-0.6-0.7-0.7-0.5-0.6-0.60.7-0.7-0.7-0.7
Locomotion velocity, session 30.10.10.50.30.30.10.70.10.4-0.20.30.10.1
Locomotion distance, session 31.71.82.2-1.4-1.3-1.5-0.9-1.5-1.31.3-1.4-1.4-1.5
Stereotopy head waving bouts, day 31.61.92.61.41.21.60.71.61.1-1.61.31.51.5
Stereotopy head waving duration, day 31.21.51.91.21.11.40.71.41.0-1.41.21.31.3
Locomotion velocity, session 75.05.55.9-2.3-2.4-2.4-2.3-2.3-2.32.3-2.4-2.4-2.3
Locomotion distance, session 74.45.66.4-2.4-2.4-2.5-1.8-2.5-2.22.5-2.4-2.5-2.5
Stereotopy head waving bouts, day 72.32.62.91.71.61.71.41.61.5-1.71.61.71.6
Stereotopy head waving duration, day 73.03.74.22.01.92.01.42.01.8-2.11.92.02.0
Locomotion velocity, session 80.30.31.7-0.3-0.70.1-1.30.2-0.9-0.1-0.5-0.0-0.1
Locomotion distance, session 83.85.78.2-2.4-2.6-2.1-2.9-2.1-2.62.2-2.5-2.2-2.2
Degree of sensitization distance0.40.40.9-0.7-0.7-0.5-0.9-0.4-0.80.6-0.7-0.5-0.5
Degree of sensitization stereotypy1.51.61.81.31.31.31.11.31.2-1.31.31.31.3
Condit. Reinf. active minus inactive responses1.01.11.3-1.0-1.1-1.1-1.1-1.0-1.01.0-1.1-1.0-1.0
Condit. Reinf. active-inactive response ratio0.00.00.10.10.1-0.00.20.00.2-0.00.10.00.0
Condit. Reinf. active responses1.51.82.0-1.3-1.4-1.4-1.3-1.3-1.31.4-1.4-1.4-1.3
Condit. Reinf. inactive responses2.12.53.1-1.6-1.5-1.7-0.9-1.7-1.41.8-1.6-1.7-1.7
Incentive salience index mean1.92.34.2-1.5-1.6-1.4-2.1-1.2-1.61.3-1.5-1.3-1.3
Condit. Reinf. lever presses3.24.28.3-2.0-2.2-1.8-2.9-1.7-2.31.7-2.1-1.8-1.8
Time in familiar zone, hab. session 12.92.84.0-1.6-1.4-1.9-0.4-2.0-1.22.0-1.6-1.9-1.8
Time in novel zone, hab. session 11.31.32.11.10.91.40.01.40.7-1.51.01.31.2
Total zone transitions, hab. session 10.71.01.1-0.9-1.0-1.1-1.1-1.0-0.91.0-1.0-1.0-1.0
Total locomotion distance, hab. session 10.50.81.0-0.9-0.9-1.0-0.6-0.9-0.70.9-0.9-0.9-0.9
Locomotion velocity, hab. session 10.20.30.4-0.5-0.5-0.7-0.2-0.6-0.30.6-0.5-0.6-0.6
Time in familiar zone, hab. session 20.20.20.4-0.5-0.4-0.6-0.3-0.6-0.30.6-0.4-0.6-0.5
Time in novel zone, hab. session 20.30.30.50.60.50.60.50.60.5-0.70.60.60.6
Total zone transitions, hab. session 20.00.00.00.00.1-0.10.2-0.10.10.10.0-0.1-0.1
Total locomotion distance, hab. session 21.11.51.9-1.2-1.2-1.4-0.6-1.3-1.01.3-1.2-1.3-1.3
Locomotion velocity, hab. session 21.21.62.1-1.3-1.3-1.4-0.8-1.4-1.11.4-1.3-1.4-1.3
Novel to familiar place preference ratio0.00.00.00.10.10.00.2-0.00.2-0.00.10.00.0
Novelty place preference0.10.10.20.30.30.30.40.20.4-0.30.30.30.3
Time in novel zone, NPP test0.20.20.30.50.50.40.40.40.5-0.40.50.40.4
Total zone transitions, NPP test1.31.82.1-1.3-1.4-1.4-1.2-1.3-1.31.3-1.4-1.4-1.4
Total locomotion distance, NPP test1.11.62.1-1.3-1.2-1.5-0.6-1.4-1.11.3-1.3-1.4-1.3
Locomotion velocity, NPP test2.02.83.6-1.7-1.6-1.9-0.9-1.8-1.41.8-1.7-1.8-1.8
Pavlov. Cond. lever latency1.11.44.21.11.30.82.00.71.5-0.71.20.80.8
Pavlov. Cond. magazine entry latency1.31.74.4-1.3-1.5-0.9-2.1-0.8-1.60.8-1.3-1.0-1.0
Pavlov. Cond. change in total contacts0.30.40.70.50.30.8-0.30.90.2-0.80.40.70.7
Pavlov. Cond. index score1.51.95.2-1.3-1.6-1.0-2.3-0.8-1.80.8-1.4-1.0-1.0
Pavlov. Cond. latency score0.91.24.3-1.0-1.3-0.6-2.1-0.5-1.40.5-1.1-0.7-0.7
Pavlov. Cond. lever contacts0.50.62.7-0.6-0.8-0.3-1.6-0.2-1.00.2-0.7-0.3-0.3
Pavlov. Cond. magazine entry number2.12.64.61.61.81.42.21.31.9-1.31.71.41.4
Pavlov. Cond. intertrial magazine entries0.30.40.8-0.5-0.3-0.80.7-0.8-0.10.9-0.4-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.1.72.15.3-1.4-1.7-1.1-2.3-1.0-1.81.0-1.5-1.1-1.1
Pavlov. Cond. response bias1.92.45.3-1.5-1.8-1.2-2.3-1.1-1.91.1-1.6-1.2-1.2
Bone: apparent density1.32.22.9-1.5-1.4-1.7-0.5-1.7-1.21.7-1.5-1.6-1.6
Bone surface0.10.20.30.40.30.50.30.50.3-0.50.40.50.5
Bone volume0.10.10.40.40.40.30.60.30.4-0.30.40.30.3
Bone: connectivity density2.94.65.1-2.2-2.2-2.3-1.3-2.3-2.12.2-2.2-2.2-2.2
Bone: cortical apparent density0.60.81.90.91.00.61.40.51.2-0.60.90.60.6
Bone: cortical area2.74.24.62.02.02.12.12.02.0-2.02.02.02.0
Bone: cortical porosity0.60.70.90.80.90.80.90.70.9-0.80.90.70.8
Bone: cortical porosity0.70.81.00.90.81.00.50.90.8-1.00.90.90.9
Bone: cortical thickness4.16.813.42.62.82.23.72.12.9-2.22.62.32.3
Bone: cortical thickness0.91.13.41.01.10.71.80.61.3-0.71.00.70.7
Bone: cortical tissue density0.50.61.50.80.90.51.20.51.1-0.50.80.60.6
Bone: elastic displacement0.30.32.20.30.50.21.50.20.5-0.20.40.30.2
Bone: elastic work2.53.26.11.71.81.72.51.61.8-1.71.71.71.6
Bone: endosteal estimation1.73.65.81.71.42.40.12.41.0-2.31.72.22.2
Bone: endosteal perimeter0.20.42.6-0.1-0.40.4-1.60.5-0.8-0.4-0.20.40.3
Bone: final force7.311.912.93.53.63.43.53.33.6-3.23.63.43.4
Bone: final moment6.610.911.73.43.43.33.33.23.4-3.13.43.23.2
Bone: marrow area1.73.65.81.71.42.40.22.41.0-2.31.72.22.2
Bone: maximum diameter0.40.71.20.70.51.1-0.21.10.2-1.10.61.01.0
Bone: maximum force6.210.711.33.33.43.33.33.23.3-3.23.43.23.2
Bone: maximum moment5.69.810.33.23.23.13.13.13.2-3.13.23.13.1
Bone: minimum diameter0.40.81.50.70.51.2-0.11.20.2-1.10.71.11.1
Bone: periosteal estimation2.75.57.22.32.12.71.42.71.8-2.62.32.62.6
Bone: periosteal perimeter1.01.62.41.21.01.50.61.60.8-1.51.21.51.5
Bone: post-yield work0.10.20.9-0.2-0.40.0-1.00.1-0.6-0.1-0.3-0.0-0.0
Bone: stiffness1.52.32.81.61.61.51.51.41.7-1.41.61.41.5
Bone: tissue strength5.25.15.52.32.32.22.22.22.3-2.22.32.22.2
Bone: trabecular number1.42.12.9-1.4-1.3-1.7-0.3-1.7-1.21.7-1.4-1.6-1.6
Bone: trabecular spacing4.25.47.12.32.22.51.02.52.1-2.72.42.52.5
Bone: trabecular thickness1.11.42.0-1.2-1.1-1.3-0.3-1.3-1.01.4-1.2-1.3-1.3
Bone: trabecular tissue density2.23.03.41.71.81.81.51.81.8-1.61.81.81.8
Breakpoint value in progressive ratio session1.31.41.6-1.1-1.2-1.3-1.0-1.1-1.21.3-1.3-1.2-1.2
Distance traveled before self-admin0.00.10.1-0.2-0.4-0.1-0.40.1-0.30.1-0.2-0.00.0
Distance traveled after self-admin0.20.20.50.20.40.5-0.10.70.2-0.40.40.60.5
Delta time in closed arm before/after self-admin0.20.20.30.50.60.40.20.40.4-0.40.50.40.4
Delta time in open arm before/after self-admin0.00.00.1-0.00.10.10.20.20.2-0.00.20.10.1
Diff in mean of infusions in LGA sessions3.84.35.2-2.2-2.0-2.2-1.5-2.0-1.92.2-2.1-2.3-2.3
Extinction: sum of active levers before priming0.50.50.7-0.6-0.7-0.8-0.4-0.8-0.60.7-0.7-0.8-0.8
Active lever presses in extinction session 60.10.10.1-0.20.3-0.30.3-0.30.00.3-0.1-0.2-0.4
Delta distance traveled before/after self-admin1.31.41.71.01.31.21.01.21.2-1.21.21.21.1
Delta ambulatory time before/after self-admin0.40.40.70.50.70.70.40.70.6-0.80.60.70.7
Time in closed arm before self-admin0.00.00.1-0.3-0.2-0.1-0.1-0.2-0.10.4-0.1-0.1-0.1
Time in closed arm after self-admin0.80.81.20.81.10.91.00.81.0-0.61.00.90.8
Time in open arm before self-admin0.20.30.5-0.4-0.7-0.5-0.6-0.3-0.7-0.0-0.6-0.4-0.4
Time in open arm after self-admin0.80.81.2-0.9-1.1-1.0-0.9-0.8-1.00.6-1.0-0.9-0.9
Sum of active levers in priming session hrs 5-60.50.50.7-0.8-0.6-0.7-0.6-0.8-0.70.8-0.8-0.8-0.9
Time to tail flick, vehicle, before self-admin0.10.10.3-0.3-0.3-0.3-0.5-0.4-0.40.2-0.4-0.3-0.3
Time to tail flick, vehicle, after self-admin0.91.02.4-1.0-1.0-0.8-1.5-0.7-1.20.9-0.9-0.8-0.7
Time to tail flick, test, before self-admin0.10.10.20.30.20.10.50.10.3-0.30.20.10.2
Time to tail flick, test, after self-admin1.11.21.7-1.1-1.1-1.0-1.3-0.9-1.30.9-1.2-0.9-1.0
Delta time to tail flick, vehicle, before/after SA0.80.81.1-0.9-0.9-0.9-1.0-0.9-1.01.0-0.9-0.9-0.8
Delta time to tail flick, test, before/after SA1.21.11.3-1.1-1.0-1.0-1.0-1.0-1.11.1-1.1-1.0-1.0
Ambulatory time before self-admin0.00.00.0-0.00.00.10.00.20.00.10.10.10.0
Ambulatory time after self-admin0.10.10.30.10.20.4-0.10.50.1-0.40.20.40.4
Total heroin consumption0.00.00.0-0.1-0.1-0.1-0.0-0.1-0.10.2-0.2-0.1-0.2
Area under the delay curve2.42.52.81.61.61.61.71.61.7-1.61.61.51.4
Delay disc. indifference point, 0s delay0.40.40.60.70.50.70.40.80.6-0.70.70.70.8
Delay disc. indifference point, 16s delay1.81.94.01.31.61.12.01.11.6-1.21.41.10.9
Delay disc. indifference point, 2s delay2.22.42.91.61.41.61.21.71.4-1.61.61.61.6
Delay disc. indifference point, 24s delay0.60.61.10.70.90.71.10.60.8-0.60.80.70.6
Delay disc. indifference point, 4s delay3.13.34.01.71.71.91.42.01.7-2.01.81.91.8
Delay disc. indifference point, 8s delay0.40.40.50.70.60.60.70.60.7-0.60.60.60.5
Delay discount exponential model param2.32.42.7-1.5-1.6-1.5-1.6-1.6-1.61.5-1.6-1.5-1.4
Delay discount hyperbolic model param2.32.52.7-1.6-1.6-1.6-1.5-1.6-1.61.6-1.6-1.6-1.5
Fecal boli incidents, locomotor time 11.01.11.4-1.0-1.1-1.1-1.0-1.0-1.01.2-1.1-1.0-1.0
Change in fecal boli incidents, locomotor task0.60.60.80.70.90.90.40.90.7-0.70.80.80.8
Time >=10cm from walls, locomotor time 10.40.40.80.50.50.8-0.30.90.2-0.50.60.70.8
Bouts of movement, locomotor time 11.41.62.0-1.3-1.3-1.2-1.4-1.3-1.31.2-1.3-1.1-1.1
Total resting periods, locomotor time 10.70.81.3-1.0-0.9-0.8-1.2-0.8-1.00.9-0.9-0.7-0.8
Rest time, locomotor task time 10.10.10.8-0.2-0.2-0.0-0.90.0-0.50.1-0.20.10.1
Distance moved, locomotor task time 10.80.91.60.90.90.81.20.91.1-1.00.90.80.8
Vertical activity count, locomotor time 10.40.40.80.60.60.50.90.60.8-0.60.70.50.5
Time >=10cm from walls, locomotor time 20.00.00.10.2-0.10.2-0.30.2-0.1-0.30.10.10.2
Bouts of movement, locomotor time 20.40.50.80.70.30.9-0.10.90.3-0.90.50.80.9
Total resting periods, locomotor time 20.20.30.50.40.00.6-0.50.7-0.0-0.70.30.60.6
Rest time, locomotor task time 20.50.63.2-0.7-0.7-0.2-1.80.0-1.10.3-0.5-0.3-0.2
Distance moved, locomotor task time 20.80.92.51.01.00.61.60.61.3-0.80.90.70.7
Vertical activity count, locomotor time 20.10.10.30.20.30.00.6-0.10.40.00.20.00.0
Weight adjusted by age3.53.94.72.11.82.11.52.01.9-2.21.92.22.1
Seeking ratio, delayed vs. immediate footshock0.50.50.70.80.70.80.60.80.7-0.70.70.80.6
Locomotion in novel chamber0.70.81.00.90.90.90.90.81.0-0.90.91.00.8
Locomotion in novel chamber post-restriction0.70.91.10.91.00.90.90.81.0-0.81.00.90.9
Progressive ratio5.66.57.22.72.52.62.42.32.6-2.72.62.52.6
Food seeking constrained by brief footshock0.00.00.1-0.0-0.2-0.20.1-0.2-0.1-0.1-0.2-0.2-0.1
Seeking ratio, punishment vs. effort4.96.06.3-2.5-2.5-2.5-2.3-2.3-2.52.5-2.5-2.5-2.5
Run reversals in cocaine runway, females0.20.20.60.40.40.20.80.20.6-0.10.40.20.2
Run reversals in cocaine runway, males0.50.41.20.70.30.8-0.20.70.2-1.10.40.80.8
Latency to leave start box in cocaine runway0.00.00.00.20.20.20.10.20.2-0.10.20.20.2
Latency to leave start box in cocaine runway, F0.30.30.4-0.5-0.6-0.6-0.6-0.5-0.60.5-0.6-0.5-0.6
Latency to leave start box in cocaine runway, M1.61.51.91.11.41.21.31.21.4-0.91.41.21.2
Cd content in liver0.60.71.60.80.90.71.30.61.0-0.60.80.70.7
Co content in liver1.51.82.61.41.51.21.51.11.6-1.21.41.21.2
Cu content in liver3.13.75.1-1.9-1.8-2.2-1.1-2.2-1.52.2-1.9-2.2-2.1
Fe content in liver0.60.72.30.80.90.71.50.60.9-0.60.80.60.6
K content in liver0.20.20.5-0.4-0.4-0.4-0.7-0.4-0.40.4-0.4-0.4-0.3
Mg content in liver2.82.95.2-1.7-1.8-1.5-2.3-1.5-1.91.5-1.7-1.5-1.4
Mn content in liver1.61.95.8-1.3-1.6-0.9-2.4-0.8-1.70.8-1.4-0.9-0.9
Na content in liver0.10.10.30.30.30.20.60.20.4-0.20.30.20.3
Rb content in liver1.11.31.5-1.2-1.1-1.2-1.1-1.2-1.11.2-1.1-1.2-1.2
Se content in liver1.11.32.4-1.2-1.4-0.8-1.5-0.8-1.60.8-1.2-0.8-0.8
Sr content in liver0.50.40.70.70.50.80.10.80.5-0.80.60.80.8
Zn content in liver0.00.00.2-0.1-0.2-0.1-0.4-0.1-0.2-0.0-0.2-0.10.0