Hub : Genes

Mrps28

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000032630 0.06 0.05 3.2e-05 0.03 0.03 0.04 0.03 1.3e-04 6.6e-04 5.8e-05 2.9e-04
2 Adipose isoform ratio ENSRNOT00000081305 0.23 0.11 0.0e+00 0.16 0.16 0.15 0.16 3.5e-17 3.5e-17 1.3e-16 4.5e-17
3 Adipose isoform ratio ENSRNOT00000100168 0.23 0.11 0.0e+00 0.15 0.16 0.15 0.16 8.5e-17 4.2e-17 8.5e-17 5.8e-17
4 Adipose intron excision ratio chr2:92820902:92855850 0.21 0.11 1.1e-16 0.13 0.14 0.13 0.13 1.1e-14 7.3e-15 1.8e-14 2.0e-14
5 Adipose intron excision ratio chr2:92852680:92855850 0.17 0.09 2.0e-13 0.11 0.11 0.1 0.11 2.2e-12 4.5e-12 1.6e-11 3.7e-12
6 Adipose mRNA stability ENSRNOG00000032630 0.07 0.05 9.0e-06 0.03 0.03 0.03 0.03 1.7e-04 1.2e-04 2.8e-04 3.8e-04
7 Brain mRNA stability ENSRNOG00000032630 0.08 0.06 7.9e-06 0.01 0.03 0.02 0.02 2.0e-02 1.8e-03 4.5e-03 5.5e-03
8 Liver gene expression ENSRNOG00000032630 0.16 0.09 4.0e-13 0.04 0.09 0.08 0.08 1.8e-05 5.9e-10 1.7e-09 1.7e-09
9 Liver intron excision ratio chr2:92820902:92855850 0.17 0.1 3.8e-13 0.09 0.1 0.1 0.1 1.0e-09 2.5e-11 3.8e-11 6.7e-11
10 Liver mRNA stability ENSRNOG00000032630 0.73 0.15 0.0e+00 0.17 0.18 0.18 0.18 4.9e-18 1.0e-19 6.9e-20 1.2e-19
11 OFC gene expression ENSRNOG00000032630 0.44 0.21 3.8e-04 0.11 0.05 0.05 0.04 1.5e-03 2.9e-02 2.5e-02 3.2e-02
12 PL gene expression ENSRNOG00000032630 0.18 0.12 1.4e-07 0.06 0.06 0.05 0.06 1.2e-05 3.0e-05 8.9e-05 4.1e-05
13 PL mRNA stability ENSRNOG00000032630 0.07 0.05 7.3e-04 0.03 0.02 0 0.02 5.0e-03 2.0e-02 1.8e-01 2.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.85.717.90.5-1.71.8-1.21.90.93.50.4-2.9-0.24.04.22.7
BMI without tail3.57.322.51.9-1.11.3-0.61.51.74.31.2-2.71.14.54.73.3
Body weight0.73.18.9-0.4-1.61.6-1.31.70.22.3-0.1-2.40.32.93.01.4
Epididymis fat weight0.51.12.10.51.3-1.31.3-1.51.00.01.11.31.3-0.4-0.50.5
Glucose1.11.74.32.10.6-0.50.8-0.51.51.71.3-0.11.41.61.61.7
Heart weight0.50.71.40.10.9-0.90.8-1.00.2-0.80.31.20.7-1.1-1.1-0.7
Left kidney weight0.61.73.0-0.11.7-1.71.6-1.71.1-0.21.21.71.7-0.9-0.90.2
Right kidney weight1.33.87.30.92.6-2.62.5-2.71.90.12.12.52.3-0.9-1.00.8
Tail length0.20.61.50.7-0.10.10.00.20.61.20.5-0.61.01.11.20.8
Length with tail0.10.20.6-0.5-0.40.3-0.40.2-0.5-0.5-0.5-0.20.5-0.2-0.4-0.8
Length without tail1.02.25.1-1.9-0.60.5-0.80.3-1.8-2.3-1.60.3-1.4-1.7-1.9-2.1
Liver weight, left0.81.33.90.4-0.70.8-0.50.90.51.60.2-1.30.42.02.01.3
Liver weight, right0.30.61.10.31.0-1.01.0-1.10.90.20.90.90.8-0.1-0.10.5
Parametrial fat weight0.10.10.70.20.2-0.20.3-0.20.40.40.40.10.80.20.30.6
Retroperitoneal fat weight0.00.10.3-0.50.2-0.20.2-0.3-0.1-0.4-0.00.30.0-0.3-0.4-0.3
Intraocular pressure1.11.64.71.0-0.60.7-0.30.70.71.90.5-1.30.62.12.21.5
Extensor digitorum longus weight4.719.054.14.4-1.61.9-0.82.42.86.82.0-4.21.47.37.45.5
Soleus weight0.72.15.12.0-0.10.20.10.41.32.31.0-1.01.12.22.22.0
Tibialis anterior weight4.816.445.12.8-3.13.3-2.43.71.05.60.2-5.2-0.16.76.74.0
Tibia length0.30.81.70.20.9-1.00.8-1.10.1-1.00.31.30.4-1.3-1.3-0.7
Number of licking bursts0.00.00.10.00.1-0.10.1-0.00.20.30.2-0.00.20.20.20.2
Food consumed during 24 hour testing period1.11.32.91.50.3-0.20.5-0.11.21.71.1-0.41.41.51.51.5
Times rat made contact with spout0.30.31.21.00.4-0.40.5-0.40.60.50.60.21.10.30.30.5
Mean time between licks in bursts1.52.03.2-1.4-1.61.6-1.71.5-1.8-1.0-1.8-1.2-1.7-0.3-0.3-1.4
Mean num. licks in bursts0.00.10.30.60.2-0.20.2-0.20.20.10.20.10.30.10.10.2
Std. dev. time between licks in bursts0.91.12.0-0.8-1.21.1-1.21.1-1.3-0.8-1.3-0.8-1.4-0.2-0.2-1.0
Water consumed over 24 hours0.40.51.81.3-0.00.00.10.10.60.90.4-0.40.70.90.90.8
Indifference point 0 sec0.40.71.9-0.30.8-0.90.7-1.0-0.0-1.10.11.20.1-1.2-1.4-0.7
Indifference point AUC0.10.10.2-0.40.1-0.10.10.0-0.1-0.4-0.10.3-0.1-0.4-0.3-0.4
Indifference point function ln k1.01.42.91.70.9-0.81.0-0.71.51.51.40.31.21.01.11.7
Indifference point function log k1.01.42.91.70.9-0.81.0-0.71.51.51.40.31.21.01.11.7
Delay discounting total patch changes 0 sec0.50.81.80.31.1-1.11.0-1.20.4-0.70.51.30.4-1.0-1.2-0.3
Delay discounting total patch changes 12 sec0.91.22.7-0.61.3-1.31.2-1.30.4-0.90.61.60.9-1.4-1.4-0.6
Delay discounting total patch changes 18 sec0.20.31.11.00.5-0.50.5-0.30.60.30.60.40.90.10.20.3
Delay discounting total patch changes 24 sec0.30.40.80.10.8-0.80.7-0.60.4-0.40.50.90.8-0.6-0.7-0.3
Delay discounting total patch changes 6 sec0.20.20.6-0.20.6-0.60.5-0.50.3-0.40.30.80.3-0.5-0.6-0.2
Delay discounting time to switch 0 sec1.32.04.5-0.6-1.91.9-1.71.9-0.90.8-1.1-2.1-1.01.41.50.2
Delay discounting water rate 0 sec0.40.71.50.61.1-1.11.1-1.20.90.00.91.10.3-0.3-0.30.5
Delay discounting water rate 12 sec0.20.20.7-0.40.3-0.30.2-0.4-0.2-0.7-0.10.6-0.3-0.8-0.7-0.5
Delay discounting water rate 18 sec0.20.20.5-0.1-0.60.5-0.60.4-0.7-0.4-0.7-0.4-0.5-0.1-0.2-0.6
Delay discounting water rate 24 sec0.30.40.70.70.8-0.80.8-0.90.80.30.80.70.60.10.10.6
Delay discounting water rate 6 sec0.30.51.61.00.7-0.70.6-0.70.2-0.50.30.81.3-0.7-0.7-0.2
Locomotor activity0.50.82.20.10.3-0.30.5-0.11.11.51.0-0.20.51.31.31.4
Locomotor testing distance0.10.20.7-0.10.2-0.10.2-0.10.60.80.5-0.10.50.70.60.6
Locomotor testing rearing0.50.81.6-0.61.1-1.11.0-1.10.5-0.50.71.31.1-0.9-1.0-0.1
Light reinforcement 10.20.30.80.80.6-0.60.7-0.50.60.30.70.50.9-0.00.10.4
Light reinforcement 21.21.64.32.1-0.20.30.00.31.01.90.8-0.9-0.11.92.01.8
Reaction time number correct0.81.12.0-1.3-1.21.1-1.31.2-1.4-0.8-1.4-0.9-0.6-0.4-0.3-0.9
Reaction time mean minus median1.51.93.71.31.5-1.51.6-1.51.81.21.81.00.60.70.61.9
Reaction time mean minus median AUC1.31.63.71.41.1-1.11.2-1.11.71.51.60.50.81.10.91.9
Reaction time num false alarms1.41.93.2-1.8-1.51.4-1.61.2-1.7-1.1-1.7-1.0-1.4-0.4-0.6-1.7
Reaction time num false alarms AUC1.21.73.4-1.9-1.31.3-1.41.0-1.7-1.2-1.6-0.8-1.2-0.6-0.8-1.7
Reaction time trials correct on left0.81.12.0-1.3-1.21.1-1.31.2-1.4-0.8-1.4-0.9-0.6-0.4-0.3-0.9
Reaction time trials on left0.81.22.1-1.5-1.21.2-1.31.2-1.4-0.9-1.5-0.9-0.7-0.4-0.3-0.9
Reaction time mean0.60.82.31.10.1-0.00.30.10.91.40.8-0.5-0.21.31.31.5
Reaction time mean AUC0.70.92.31.20.00.10.20.10.91.40.7-0.6-0.21.41.41.5
Median of all reaction times0.70.92.50.9-0.60.6-0.40.70.41.40.2-1.1-0.41.51.61.2
Reaction time omissions0.20.20.8-0.30.2-0.10.2-0.10.50.60.4-0.1-0.80.60.50.9
Reaction time false alarm rate0.10.10.4-0.5-0.20.2-0.2-0.1-0.2-0.3-0.2-0.0-0.4-0.1-0.3-0.6
Reaction time premature initiation rate1.01.43.6-0.31.2-1.31.1-1.30.4-0.80.61.51.9-1.3-1.5-0.9
Reaction time premature initiations0.70.92.3-0.90.5-0.60.4-0.6-0.3-1.2-0.21.01.5-1.4-1.5-1.2
Std. dev. reaction times1.31.83.61.21.4-1.31.5-1.31.81.41.80.80.60.80.81.9
Reaction time trials completed0.81.22.1-1.5-1.21.2-1.31.2-1.4-0.9-1.5-0.9-0.7-0.4-0.3-0.9
Reaction time trials AUC1.01.52.6-1.6-1.41.3-1.41.4-1.6-1.0-1.6-1.0-0.9-0.4-0.3-1.0
Social response proportion0.70.81.40.91.1-1.01.1-1.21.10.51.10.80.70.40.10.8
Social responses1.41.93.51.91.4-1.31.5-1.41.71.11.70.91.50.80.61.5
Social time0.60.82.3-0.9-0.0-0.0-0.2-0.2-0.9-1.5-0.80.5-0.0-1.3-1.5-1.5
Conditioned locomotion0.40.41.0-0.2-0.70.7-0.80.7-0.8-0.6-0.8-0.5-1.0-0.2-0.2-0.7
Cocaine response after cond. corrected0.80.92.4-1.30.5-0.60.4-0.7-0.4-1.3-0.21.0-0.6-1.6-1.6-0.9
Cocaine response after cond. not corrected1.61.84.9-1.30.5-0.60.3-0.7-0.8-2.0-0.61.3-0.9-2.2-2.2-1.5
Cocaine response before conditioning0.40.41.20.1-0.40.3-0.40.2-0.9-1.1-0.80.1-0.5-0.8-0.8-1.1
Saline control response1.21.62.9-0.8-1.41.4-1.51.4-1.7-1.1-1.7-1.0-1.1-0.4-0.4-1.3
Condit. Reinf. active minus inactive responses2.22.84.7-2.2-1.71.6-1.81.5-2.1-1.6-2.1-1.0-1.7-0.8-0.8-2.0
Condit. Reinf. active-inactive response ratio1.71.82.7-1.4-1.61.6-1.71.6-1.6-0.6-1.6-1.3-1.50.00.0-1.1
Condit. Reinf. active responses3.65.08.5-2.9-2.01.9-2.21.7-2.9-2.5-2.8-1.0-2.2-1.6-1.6-2.9
Condit. Reinf. inactive responses1.11.42.9-1.4-0.80.8-1.00.7-1.5-1.5-1.4-0.2-1.2-1.2-1.2-1.7
Condit. Reinf. lever presses0.91.22.1-1.3-1.00.9-1.10.8-1.4-1.3-1.4-0.4-0.8-0.8-0.8-1.5
Condit. Reinf. lever reinforcers received3.24.47.7-2.8-1.81.7-2.01.5-2.7-2.4-2.6-0.8-2.1-1.6-1.6-2.7
Pavlov. Cond. lever latency0.40.61.71.30.1-0.10.20.00.81.20.7-0.30.11.11.11.1
Pavlov. Cond. magazine entry latency0.10.10.20.1-0.20.3-0.20.2-0.00.3-0.1-0.3-0.40.40.40.3
Pavlov. Cond. change in total contacts1.21.72.8-1.5-1.61.6-1.71.6-1.5-0.6-1.6-1.4-0.90.10.1-1.1
Pavlov. Cond. index score0.40.50.9-0.7-0.90.9-0.90.9-0.9-0.4-0.9-0.8-0.50.00.0-0.6
Pavlov. Cond. latency score0.20.30.6-0.6-0.70.6-0.70.6-0.7-0.4-0.8-0.5-0.3-0.1-0.1-0.5
Pavlov. Cond. lever contacts0.50.71.9-1.4-0.50.4-0.60.4-1.0-1.2-1.0-0.0-0.5-0.9-0.9-1.2
Pavlov. Cond. magazine entry number0.20.30.60.00.6-0.60.6-0.60.2-0.50.30.80.2-0.7-0.7-0.3
Pavlov. Cond. intertrial magazine entries0.20.20.4-0.0-0.60.6-0.60.7-0.40.1-0.5-0.6-0.50.30.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.30.40.8-0.7-0.80.8-0.80.7-0.9-0.5-0.9-0.6-0.4-0.2-0.2-0.7
Pavlov. Cond. response bias0.71.01.9-1.4-1.11.1-1.11.0-1.2-0.7-1.2-0.8-0.9-0.3-0.3-0.9
Conditioned reinforcement - actives2.52.56.1-2.5-0.80.7-1.00.5-1.8-2.1-1.70.0-1.9-1.7-1.6-2.2
Conditioned reinforcement - inactives1.11.22.7-1.6-0.30.2-0.40.0-1.1-1.5-1.00.3-1.4-1.4-1.4-1.6
Conditioned locomotion0.20.20.7-0.1-0.30.3-0.40.2-0.7-0.8-0.6-0.1-0.2-0.6-0.6-0.8
Intermittent access intake day 1-15 change1.11.12.7-0.61.0-1.10.8-1.1-0.0-1.30.21.50.3-1.6-1.6-0.9
Intermittent access intake escalation0.70.71.8-0.50.7-0.80.6-0.8-0.1-1.10.01.2-0.0-1.3-1.3-0.8
Intermittent access intake escalation 21.71.74.5-1.40.5-0.60.3-0.7-0.8-2.0-0.61.3-0.4-2.1-2.1-1.7
Intermitt. access day 1 inactive lever presses0.70.81.91.41.0-1.01.1-0.81.10.61.10.80.60.20.20.9
Intermitt. access day 15 inactive lever presses2.22.45.3-0.11.9-1.91.7-2.00.6-1.30.92.30.8-2.0-2.1-0.6
Intermitt. access escalation Index0.60.61.71.10.6-0.60.7-0.50.80.50.80.41.30.30.31.0
Intermittent access day 1 total infusions2.73.06.4-2.2-0.60.4-0.80.2-1.9-2.5-1.70.4-2.0-2.3-2.3-2.4
Intermittent access day 15 total infusions3.54.09.6-2.6-0.0-0.1-0.3-0.4-1.8-3.1-1.51.2-1.5-3.0-3.0-2.7
Intermittent access terminal intake (last 3 days)3.63.99.3-2.70.3-0.4-0.1-0.6-1.6-3.0-1.31.4-1.4-3.1-3.1-2.6
Intermittent access total infusions2.83.17.6-2.20.2-0.3-0.1-0.6-1.5-2.7-1.21.2-1.3-2.7-2.8-2.3
Intermittent access day 1 locomotion0.50.51.1-1.0-0.0-0.0-0.1-0.2-0.6-1.0-0.50.4-0.7-1.0-1.1-0.8
Intermittent access day 15 total locomotion0.60.61.2-0.7-0.50.5-0.60.4-1.0-1.1-1.0-0.1-0.6-0.8-0.9-1.1
Intermittent access total locomotion0.80.92.4-0.80.2-0.20.0-0.4-0.7-1.4-0.60.7-0.9-1.5-1.5-1.3
Intermittent access standard deviation1.71.84.0-0.41.5-1.51.3-1.60.3-1.40.62.0-0.3-1.9-1.9-0.7
Cocaine induced anxiety0.40.41.01.00.8-0.80.8-0.70.60.10.70.71.0-0.2-0.20.1
Post-drug Anxiety0.70.75.22.30.1-0.00.20.10.60.90.5-0.30.90.80.80.6
Baseline Anxiety0.30.30.50.4-0.70.7-0.70.7-0.6-0.2-0.7-0.6-0.60.10.1-0.3
Lifetime Intake3.13.58.8-2.30.3-0.50.0-0.7-1.5-2.9-1.11.4-1.5-2.9-3.0-2.3
Incentive Sensitization - Responses2.12.14.0-1.5-1.31.2-1.51.2-2.0-1.8-1.9-0.6-0.8-1.2-1.1-1.9
Incentive Sensitization - Breakpoint1.71.73.4-1.3-1.11.1-1.31.0-1.8-1.7-1.7-0.4-0.6-1.2-1.1-1.8
Progressive ratio test 1 active lever presses2.72.86.0-1.11.8-1.91.6-2.10.3-1.70.62.4-0.5-2.4-2.4-0.8
Progressive ratio test 1 breakpoint2.42.45.6-1.21.6-1.71.4-1.90.2-1.60.52.2-0.5-2.3-2.4-0.8
Progressive ratio test 1 inactive lever presses0.60.61.3-0.31.0-1.11.0-1.20.5-0.40.61.2-0.2-0.8-0.90.1
Progressive ratio test 2 active lever presses1.41.53.8-1.50.1-0.2-0.1-0.3-1.1-1.9-0.90.8-0.5-1.9-1.9-1.6
Progressive ratio test 2 breakpoint1.21.43.5-1.3-0.1-0.0-0.3-0.2-1.2-1.9-1.00.6-0.6-1.8-1.8-1.7
Progressive ratio test 2 inactive lever presses0.70.92.4-0.90.4-0.50.3-0.6-0.5-1.4-0.31.00.2-1.6-1.5-1.2
Total sessions with >9 infusions1.61.84.8-1.90.7-0.80.5-0.9-0.6-1.9-0.41.4-0.6-2.1-2.2-1.3
Short access day 1 total inactive lever presses1.11.23.4-0.70.9-0.90.7-1.0-0.3-1.5-0.11.40.6-1.8-1.9-1.0
Short access day 10 total inactive lever presses1.51.64.12.01.4-1.41.5-1.31.60.91.61.01.10.20.31.1
Short access day 1 total infusions1.41.54.0-1.21.0-1.10.8-1.2-0.2-1.60.01.6-0.5-2.0-2.0-0.9
Short access day 10 total infusions2.42.67.5-1.21.0-1.10.8-1.4-0.6-2.3-0.31.9-1.0-2.7-2.7-1.5
Short access total infusions2.93.38.9-1.90.6-0.70.3-1.0-1.2-2.7-0.91.6-1.6-2.9-3.0-2.1
Short access day 1 locomotion0.90.91.8-0.41.3-1.31.3-1.31.00.21.11.21.2-0.4-0.50.4
Short access day 10 total locomotion0.10.10.60.20.3-0.30.4-0.30.40.40.40.2-0.80.20.20.4
Short access total locomotion0.40.40.7-0.80.7-0.70.6-0.80.2-0.50.30.8-0.0-0.8-0.9-0.3
Compulsive drug intake1.51.54.60.8-0.50.6-0.40.90.71.90.5-1.3-0.12.12.11.5
One hour access (0.3 mA shock)1.72.06.0-2.4-0.1-0.0-0.3-0.2-1.3-2.1-1.10.7-0.3-2.1-2.1-1.9
One hour access (shock baseline)3.23.810.2-2.60.6-0.70.3-1.0-1.3-2.9-1.01.7-0.6-3.1-3.2-2.3
Number of responses in last shaping day0.40.41.60.50.7-0.70.7-0.60.60.20.60.61.3-0.1-0.20.4
Context. condit. distance diff. score0.50.61.10.70.8-0.70.8-0.81.00.61.00.51.00.30.30.8
Locomotion velocity, session 10.20.20.60.30.1-0.00.2-0.10.50.80.5-0.20.40.80.80.7
Locomotion distance, session 10.30.30.8-0.3-0.70.7-0.60.6-0.20.5-0.3-0.9-0.40.80.80.1
Locomotion velocity, session 20.60.82.40.7-0.40.5-0.20.50.51.40.4-0.9-0.31.51.51.0
Locomotion distance, session 21.31.83.4-1.0-1.71.7-1.71.7-1.20.1-1.3-1.7-1.80.80.8-0.5
Locomotion velocity, session 30.50.60.90.90.9-0.91.0-1.00.80.20.90.90.6-0.1-0.10.5
Locomotion distance, session 30.30.40.7-0.5-0.60.6-0.70.6-0.8-0.5-0.8-0.4-0.8-0.2-0.3-0.7
Stereotopy head waving bouts, day 30.10.10.2-0.1-0.20.2-0.20.1-0.4-0.4-0.40.00.4-0.4-0.4-0.4
Stereotopy head waving duration, day 30.50.61.71.10.6-0.60.7-0.50.90.80.90.31.30.60.61.0
Locomotion velocity, session 78.59.315.5-3.8-2.52.4-2.82.1-3.9-3.6-3.8-1.1-3.4-2.4-2.4-3.9
Locomotion distance, session 73.24.19.6-3.1-0.90.8-1.20.6-2.3-2.8-2.10.2-2.0-2.4-2.3-2.8
Stereotopy head waving bouts, day 70.40.51.31.1-0.40.4-0.30.50.30.90.1-0.70.21.11.10.7
Stereotopy head waving duration, day 70.91.13.01.70.3-0.30.5-0.21.11.51.0-0.31.11.41.41.4
Locomotion velocity, session 81.01.13.30.9-0.20.3-0.00.40.91.80.7-0.9-0.21.81.81.4
Locomotion distance, session 80.20.40.90.1-0.60.6-0.50.60.00.8-0.1-0.8-0.41.01.00.4
Degree of sensitization distance0.60.62.2-1.5-0.30.2-0.40.2-0.8-1.1-0.80.1-0.9-0.9-0.9-0.9
Degree of sensitization stereotypy1.41.63.82.00.1-0.00.30.11.21.91.0-0.61.01.81.81.7
Condit. Reinf. active minus inactive responses4.34.79.3-0.5-2.92.9-2.73.0-1.70.6-2.0-3.1-2.01.91.9-0.2
Condit. Reinf. active-inactive response ratio6.06.512.5-0.5-3.33.4-3.23.5-2.10.6-2.4-3.5-2.82.12.1-0.3
Condit. Reinf. active responses3.84.69.1-0.5-2.82.9-2.73.0-1.70.6-2.0-3.0-1.81.91.8-0.2
Condit. Reinf. inactive responses0.10.20.50.3-0.20.2-0.10.20.30.60.2-0.40.40.70.70.5
Incentive salience index mean4.04.89.7-0.6-2.93.0-2.83.0-1.70.7-2.0-3.1-1.72.01.9-0.2
Condit. Reinf. lever presses1.52.04.4-0.4-1.81.9-1.71.9-0.80.9-1.1-2.1-0.81.51.50.2
Time in familiar zone, hab. session 11.81.72.51.51.5-1.51.6-1.41.60.71.61.21.50.10.11.3
Time in novel zone, hab. session 10.50.51.0-0.9-0.30.2-0.40.1-0.8-1.0-0.70.1-0.7-0.9-0.9-1.0
Total zone transitions, hab. session 10.30.50.9-0.1-0.90.9-0.90.9-0.60.1-0.7-0.9-0.90.50.60.0
Total locomotion distance, hab. session 11.01.42.4-1.0-1.51.5-1.51.5-1.4-0.5-1.5-1.3-1.30.20.2-0.9
Locomotion velocity, hab. session 11.21.73.0-0.9-1.71.7-1.71.7-1.3-0.0-1.4-1.7-1.30.70.7-0.5
Time in familiar zone, hab. session 22.32.35.10.42.1-2.12.0-2.21.3-0.51.52.30.2-1.3-1.20.5
Time in novel zone, hab. session 21.31.32.8-0.0-1.61.6-1.51.7-1.00.3-1.1-1.7-0.10.90.9-0.4
Total zone transitions, hab. session 20.20.20.40.30.5-0.50.6-0.50.60.30.60.4-0.50.20.10.7
Total locomotion distance, hab. session 20.20.31.2-0.2-0.70.7-0.60.7-0.40.1-0.5-0.7-1.10.40.40.2
Locomotion velocity, hab. session 20.20.31.1-0.4-0.60.6-0.60.6-0.4-0.0-0.5-0.6-1.10.30.30.1
Novel to familiar place preference ratio0.30.30.80.3-0.40.4-0.30.50.20.80.1-0.60.50.90.90.5
Novelty place preference0.20.20.60.3-0.10.1-0.00.20.40.80.3-0.40.60.80.80.6
Time in novel zone, NPP test0.50.51.10.70.2-0.20.3-0.10.81.10.7-0.20.81.01.01.0
Total zone transitions, NPP test0.00.10.20.20.00.00.0-0.00.20.30.2-0.1-0.50.40.40.4
Total locomotion distance, NPP test0.20.30.6-0.0-0.70.7-0.70.7-0.40.2-0.5-0.8-0.50.50.50.0
Locomotion velocity, NPP test0.30.50.8-0.6-0.90.9-0.90.8-0.8-0.3-0.9-0.7-0.70.10.0-0.6
Pavlov. Cond. lever latency0.81.01.91.11.3-1.31.3-1.30.8-0.30.91.41.0-0.7-0.70.1
Pavlov. Cond. magazine entry latency0.40.51.00.1-0.80.8-0.70.8-0.20.6-0.3-1.0-0.31.00.90.4
Pavlov. Cond. change in total contacts1.51.63.40.2-1.31.4-1.21.5-0.21.4-0.4-1.8-0.21.81.80.8
Pavlov. Cond. index score0.40.61.3-0.2-0.80.9-0.70.9-0.20.8-0.3-1.1-0.31.11.10.5
Pavlov. Cond. latency score0.40.51.1-0.3-0.80.8-0.70.8-0.20.7-0.3-1.0-0.30.90.90.4
Pavlov. Cond. lever contacts1.61.93.4-1.3-1.81.8-1.81.8-1.30.1-1.4-1.8-1.30.70.7-0.5
Pavlov. Cond. magazine entry number0.60.82.3-0.90.4-0.50.3-0.6-0.4-1.3-0.30.9-0.2-1.5-1.5-1.2
Pavlov. Cond. intertrial magazine entries1.51.84.8-1.0-0.50.4-0.70.3-1.6-2.1-1.40.3-0.4-1.9-1.9-2.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.20.0-0.70.7-0.60.7-0.00.9-0.1-1.00.11.11.10.6
Pavlov. Cond. response bias0.91.12.50.0-1.31.3-1.11.3-0.40.9-0.6-1.6-0.51.41.40.5
Bone: apparent density0.91.53.5-1.2-0.90.8-1.00.7-1.6-1.6-1.5-0.2-1.3-1.3-1.3-1.9
Bone surface1.52.64.5-1.7-1.71.7-1.91.6-2.1-1.4-2.1-1.1-1.5-0.9-0.8-2.0
Bone volume1.83.05.4-1.5-1.71.7-1.91.5-2.3-1.7-2.2-1.0-1.6-1.1-1.1-2.3
Bone: connectivity density1.11.83.6-1.7-0.80.8-1.00.7-1.6-1.7-1.5-0.2-1.5-1.4-1.4-1.9
Bone: cortical apparent density0.20.30.80.50.2-0.20.3-0.20.60.70.5-0.1-0.00.70.70.9
Bone: cortical area0.50.81.80.6-0.80.8-0.60.90.11.1-0.1-1.20.41.41.30.6
Bone: cortical porosity0.10.10.1-0.2-0.30.3-0.30.3-0.10.1-0.2-0.30.00.30.20.0
Bone: cortical porosity0.00.00.1-0.2-0.20.2-0.20.2-0.20.0-0.2-0.2-0.10.20.1-0.0
Bone: cortical thickness0.40.61.70.9-0.50.5-0.30.60.31.10.2-0.90.41.31.30.9
Bone: cortical thickness2.42.86.72.30.2-0.10.40.11.62.61.4-0.81.32.42.42.3
Bone: cortical tissue density0.20.30.70.50.2-0.20.3-0.20.60.70.6-0.0-0.00.60.70.9
Bone: elastic displacement0.80.91.4-1.0-1.11.1-1.11.1-1.1-0.6-1.2-0.8-1.0-0.0-0.1-0.9
Bone: elastic work0.40.50.9-0.6-0.90.9-0.90.9-0.8-0.2-0.9-0.8-0.60.10.1-0.5
Bone: endosteal estimation1.32.85.6-0.7-2.32.3-2.32.4-1.70.1-1.8-2.3-0.90.90.9-0.8
Bone: endosteal perimeter0.40.71.2-1.1-1.01.0-1.11.0-1.0-0.4-1.0-0.9-0.4-0.1-0.1-0.9
Bone: final force0.71.12.30.7-1.11.2-1.01.2-0.21.1-0.4-1.50.21.51.50.6
Bone: final moment0.50.91.90.5-1.01.1-0.91.1-0.11.0-0.3-1.40.21.31.40.5
Bone: marrow area1.32.85.8-0.6-2.32.3-2.32.4-1.60.2-1.8-2.3-0.91.01.0-0.7
Bone: maximum diameter0.30.61.60.4-0.30.3-0.20.40.51.30.4-0.70.81.21.20.9
Bone: maximum force0.40.81.71.0-0.70.8-0.60.90.11.1-0.0-1.10.71.31.30.7
Bone: maximum moment0.40.61.30.8-0.70.7-0.60.80.11.0-0.1-1.00.71.21.10.5
Bone: minimum diameter2.85.210.6-0.8-3.13.2-3.03.3-2.00.6-2.3-3.3-1.31.71.7-0.7
Bone: periosteal estimation1.53.06.9-0.1-2.32.4-2.22.5-1.20.9-1.4-2.6-0.51.71.7-0.1
Bone: periosteal perimeter0.20.40.8-0.1-0.70.8-0.70.8-0.20.5-0.3-0.90.10.70.70.1
Bone: post-yield work0.81.02.00.31.2-1.31.1-1.30.5-0.60.71.41.3-1.2-1.2-0.2
Bone: stiffness0.20.31.11.00.1-0.00.10.00.50.70.4-0.21.00.60.60.6
Bone: tissue strength0.70.71.6-0.20.9-1.00.8-1.10.1-0.90.31.30.0-1.1-1.2-0.4
Bone: trabecular number0.30.51.4-0.5-0.30.3-0.40.2-0.8-1.0-0.70.1-0.8-0.9-0.9-1.2
Bone: trabecular spacing0.10.10.40.2-0.20.2-0.10.20.20.50.1-0.40.10.60.60.5
Bone: trabecular thickness0.70.92.3-0.5-0.60.5-0.70.4-1.2-1.3-1.1-0.1-0.8-1.1-1.1-1.5
Bone: trabecular tissue density1.11.52.71.61.4-1.31.5-1.31.60.91.61.01.00.50.41.4
Breakpoint value in progressive ratio session0.20.20.50.3-0.30.3-0.20.50.10.60.0-0.50.30.60.70.3
Distance traveled before self-admin1.41.53.51.50.7-0.60.8-0.31.51.71.4-0.01.01.41.31.9
Distance traveled after self-admin0.91.02.70.30.9-0.81.0-0.71.41.31.30.30.31.00.91.7
Delta time in closed arm before/after self-admin1.71.74.12.01.0-0.91.1-0.71.71.61.60.30.91.21.11.7
Delta time in open arm before/after self-admin0.20.20.4-0.1-0.0-0.0-0.10.0-0.4-0.7-0.40.2-0.6-0.6-0.6-0.5
Diff in mean of infusions in LGA sessions0.91.02.50.1-1.01.0-0.81.20.01.2-0.2-1.40.71.61.60.5
Extinction: sum of active levers before priming0.10.10.2-0.10.1-0.10.2-0.00.30.40.3-0.10.20.40.40.3
Active lever presses in extinction session 60.00.00.2-0.10.1-0.10.1-0.1-0.0-0.20.00.2-0.5-0.2-0.2-0.1
Delta distance traveled before/after self-admin0.50.62.8-1.7-0.50.4-0.60.2-0.8-0.7-0.8-0.2-1.2-0.4-0.4-0.7
Delta ambulatory time before/after self-admin0.90.94.5-2.1-0.20.1-0.3-0.1-0.9-1.2-0.80.3-1.1-1.0-1.0-1.1
Time in closed arm before self-admin1.21.43.2-1.8-0.0-0.0-0.2-0.1-1.1-1.7-0.90.6-1.4-1.6-1.6-1.5
Time in closed arm after self-admin0.60.61.20.61.0-0.91.0-0.81.10.61.10.70.40.30.30.9
Time in open arm before self-admin0.40.51.00.3-0.80.8-0.70.6-0.20.7-0.3-1.00.60.90.90.2
Time in open arm after self-admin0.30.30.70.5-0.40.5-0.30.50.10.7-0.0-0.7-0.10.80.80.5
Sum of active levers in priming session hrs 5-60.60.51.1-0.9-0.60.6-0.70.7-0.9-0.8-0.9-0.3-0.8-0.5-0.5-1.0
Time to tail flick, vehicle, before self-admin0.40.40.9-0.5-0.40.4-0.50.4-0.8-0.9-0.8-0.0-0.5-0.7-0.8-0.9
Time to tail flick, vehicle, after self-admin1.11.12.2-1.3-0.60.6-0.80.5-1.3-1.4-1.2-0.1-1.2-1.1-1.1-1.5
Time to tail flick, test, before self-admin0.30.30.60.50.7-0.70.6-0.60.4-0.10.50.7-0.8-0.3-0.30.2
Time to tail flick, test, after self-admin0.70.72.2-0.40.6-0.70.5-0.9-0.3-1.3-0.11.10.2-1.5-1.5-0.6
Delta time to tail flick, vehicle, before/after SA1.00.92.3-1.5-0.50.4-0.60.3-1.1-1.4-1.00.1-1.0-1.1-1.1-1.2
Delta time to tail flick, test, before/after SA0.60.52.00.30.9-0.90.9-0.90.6-0.00.70.81.4-0.4-0.40.5
Ambulatory time before self-admin0.80.92.21.30.5-0.50.7-0.41.11.31.00.00.61.01.01.5
Ambulatory time after self-admin0.10.10.5-0.70.1-0.10.2-0.10.30.30.30.0-0.60.40.30.5
Total heroin consumption0.30.30.5-0.5-0.70.7-0.70.6-0.6-0.3-0.7-0.6-0.70.00.0-0.6
Area under the delay curve1.11.12.21.20.8-0.80.9-0.71.31.31.30.31.50.90.91.4
Delay disc. indifference point, 0s delay0.20.21.1-0.30.5-0.50.5-0.40.50.20.50.41.10.10.10.4
Delay disc. indifference point, 16s delay0.50.51.01.00.4-0.40.5-0.30.91.00.8-0.00.10.80.81.0
Delay disc. indifference point, 2s delay0.70.81.6-0.8-1.11.1-1.01.1-0.50.5-0.6-1.30.21.10.8-0.1
Delay disc. indifference point, 24s delay0.70.72.31.50.9-0.90.9-0.90.90.40.90.70.90.00.00.4
Delay disc. indifference point, 4s delay2.22.46.91.00.7-0.71.0-0.51.92.21.7-0.11.51.91.92.6
Delay disc. indifference point, 8s delay1.21.32.11.11.4-1.41.4-1.41.30.41.31.21.4-0.1-0.10.9
Delay discount exponential model param1.01.02.3-1.2-0.80.8-1.00.8-1.2-1.1-1.2-0.4-1.5-0.7-0.7-1.3
Delay discount hyperbolic model param1.01.12.4-1.0-0.80.7-0.90.7-1.3-1.3-1.2-0.2-1.5-1.0-0.9-1.4
Fecal boli incidents, locomotor time 10.20.20.8-0.1-0.30.3-0.40.3-0.6-0.5-0.5-0.1-0.9-0.2-0.4-0.9
Change in fecal boli incidents, locomotor task0.40.40.7-0.50.7-0.70.7-0.90.3-0.40.40.90.7-0.7-0.7-0.0
Time >=10cm from walls, locomotor time 10.20.21.0-1.0-0.40.4-0.40.4-0.5-0.3-0.5-0.3-0.0-0.1-0.0-0.5
Bouts of movement, locomotor time 13.23.65.82.42.4-2.42.4-2.32.10.52.22.11.7-0.5-0.31.0
Total resting periods, locomotor time 11.61.83.21.71.8-1.81.8-1.81.30.01.51.70.5-0.7-0.50.4
Rest time, locomotor task time 11.31.52.61.61.6-1.61.6-1.61.30.21.41.40.5-0.4-0.30.6
Distance moved, locomotor task time 10.50.61.5-0.7-0.80.8-0.70.9-0.30.5-0.4-0.9-1.20.80.80.4
Vertical activity count, locomotor time 11.41.53.1-1.1-1.51.5-1.41.6-0.60.9-0.8-1.80.01.51.30.4
Time >=10cm from walls, locomotor time 20.40.51.0-0.3-1.01.0-0.91.0-0.60.1-0.7-1.00.20.50.5-0.2
Bouts of movement, locomotor time 24.65.011.33.42.5-2.42.6-2.32.61.32.71.92.50.30.41.9
Total resting periods, locomotor time 25.96.313.93.72.8-2.72.9-2.62.91.53.02.13.10.30.52.0
Rest time, locomotor task time 22.32.65.92.41.7-1.61.8-1.61.91.11.91.22.20.50.61.3
Distance moved, locomotor task time 20.40.53.2-1.0-0.40.4-0.40.5-0.20.3-0.2-0.5-1.80.40.30.5
Vertical activity count, locomotor time 22.02.24.4-0.6-1.51.6-1.31.7-0.31.4-0.5-2.0-1.72.11.91.1
Weight adjusted by age0.30.41.2-1.1-0.40.4-0.50.4-0.6-0.5-0.6-0.2-1.0-0.3-0.4-0.7
Seeking ratio, delayed vs. immediate footshock2.02.36.4-0.31.0-1.00.7-1.3-0.5-2.2-0.21.8-1.7-2.5-2.4-1.6
Locomotion in novel chamber0.81.02.70.8-0.80.9-0.71.00.11.3-0.1-1.3-0.61.61.60.6
Locomotion in novel chamber post-restriction0.70.82.61.60.9-0.91.0-0.91.00.61.10.71.10.10.20.5
Progressive ratio2.42.84.71.72.0-2.02.1-1.92.11.02.21.61.10.20.11.8
Food seeking constrained by brief footshock2.42.96.20.3-2.02.0-1.82.1-0.61.5-0.8-2.5-1.52.32.20.6
Seeking ratio, punishment vs. effort3.94.88.3-1.6-2.92.9-2.92.8-2.4-0.4-2.5-2.7-2.20.80.8-1.5
Run reversals in cocaine runway, females1.51.54.01.10.2-0.10.4-0.11.32.01.1-0.50.91.91.91.6
Run reversals in cocaine runway, males1.51.43.80.2-1.01.1-0.81.30.21.6-0.1-1.60.21.91.90.9
Latency to leave start box in cocaine runway0.10.10.5-0.30.2-0.20.1-0.2-0.2-0.6-0.10.40.4-0.7-0.6-0.3
Latency to leave start box in cocaine runway, F0.80.92.8-1.00.2-0.30.0-0.2-0.8-1.6-0.60.80.3-1.7-1.6-1.1
Latency to leave start box in cocaine runway, M0.30.30.91.0-0.30.3-0.20.30.20.70.1-0.60.10.80.80.5
Cd content in liver1.01.11.91.21.0-1.01.1-0.91.41.11.40.61.30.60.61.3
Co content in liver2.22.54.31.11.9-1.81.9-1.62.01.22.11.42.00.30.31.6
Cu content in liver1.51.85.3-1.20.8-0.90.6-1.1-0.5-1.8-0.31.50.2-2.3-2.3-1.6
Fe content in liver1.82.13.2-1.5-1.71.7-1.81.7-1.7-0.8-1.8-1.4-1.6-0.0-0.0-1.3
K content in liver0.80.82.3-1.10.1-0.2-0.0-0.3-0.7-1.3-0.50.7-0.4-1.5-1.5-1.1
Mg content in liver1.41.42.7-1.6-0.80.7-0.90.7-1.4-1.5-1.3-0.2-1.1-1.3-1.3-1.6
Mn content in liver0.30.40.7-0.4-0.50.5-0.60.5-0.8-0.7-0.8-0.2-0.6-0.5-0.5-0.8
Na content in liver0.30.30.80.40.6-0.60.7-0.70.60.20.60.50.9-0.0-0.00.5
Rb content in liver0.00.00.2-0.20.2-0.20.2-0.00.1-0.10.10.2-0.5-0.2-0.20.1
Se content in liver0.20.20.6-0.30.3-0.30.2-0.5-0.1-0.6-0.00.50.5-0.7-0.7-0.5
Sr content in liver0.20.20.4-0.6-0.50.5-0.50.5-0.4-0.0-0.4-0.5-0.30.20.2-0.2
Zn content in liver0.90.92.7-0.90.7-0.70.5-0.8-0.3-1.3-0.11.20.3-1.6-1.6-1.0