Hub : Genes

Zfp641

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000032447 0.08 0.06 1.5e-03 0 0.02 0.02 0.01 1.2e-01 5.3e-03 4.3e-03 1.8e-02
2 Adipose intron excision ratio chr7:129440320:129441506 0.04 0.04 5.0e-03 0.01 0 0.01 0 4.7e-02 1.4e-01 4.1e-02 9.8e-02
3 Adipose mRNA stability ENSRNOG00000032447 0.21 0.1 0.0e+00 0.18 0.18 0.18 0.18 2.0e-19 4.9e-20 3.9e-20 3.7e-20
4 BLA gene expression ENSRNOG00000032447 0.36 0.2 0.0e+00 0.35 0.24 0.33 0.22 9.7e-20 2.8e-13 3.5e-18 9.7e-12
5 BLA mRNA stability ENSRNOG00000032447 0.06 0.05 6.4e-04 0.05 0.05 0.04 0.05 9.3e-04 1.6e-03 4.0e-03 1.3e-03
6 Brain gene expression ENSRNOG00000032447 0.27 0.12 0.0e+00 0.32 0.32 0.33 0.34 6.9e-30 1.0e-30 4.3e-31 5.4e-32
7 Brain mRNA stability ENSRNOG00000032447 0.22 0.11 0.0e+00 0.23 0.22 0.21 0.22 4.1e-21 1.2e-19 3.5e-19 1.2e-20
8 IL gene expression ENSRNOG00000032447 0.22 0.14 4.3e-05 0.14 0.17 0.16 0.16 3.2e-04 6.8e-05 9.4e-05 1.1e-04
9 LHb gene expression ENSRNOG00000032447 0.23 0.13 1.8e-05 0.12 0.14 0.13 0.14 9.1e-04 4.0e-04 6.2e-04 2.9e-04
10 Liver gene expression ENSRNOG00000032447 0.09 0.06 7.5e-06 0.03 0.04 0.03 0.04 3.4e-04 2.7e-05 2.1e-04 8.1e-05
11 NAcc gene expression ENSRNOG00000032447 0.1 0.06 2.1e-09 0.11 0.11 0.11 0.1 2.8e-08 1.1e-08 1.8e-08 3.1e-08
12 NAcc mRNA stability ENSRNOG00000032447 0.04 0.03 3.1e-03 0.03 0.03 0.03 0.03 4.4e-03 4.0e-03 4.4e-03 5.2e-03
13 OFC gene expression ENSRNOG00000032447 0.31 0.21 5.1e-05 0.16 0.14 0.1 0.14 9.8e-05 2.6e-04 2.0e-03 2.7e-04
14 PL gene expression ENSRNOG00000032447 0.48 0.2 0.0e+00 0.31 0.3 0.31 0.32 2.6e-24 3.9e-23 6.1e-24 3.8e-25
15 PL mRNA stability ENSRNOG00000032447 0.09 0.06 4.4e-06 0.07 0.07 0.07 0.07 2.5e-06 5.8e-06 3.8e-06 5.3e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail4.012.820.0-1.33.53.44.53.43.73.14.04.04.13.84.03.33.33.2
BMI without tail0.10.20.5-0.10.60.50.7-0.10.40.10.40.20.60.40.40.50.30.1
Body weight6.125.735.0-2.85.25.15.94.95.34.75.65.64.95.45.54.94.94.7
Epididymis fat weight0.20.51.60.10.60.51.20.10.60.30.80.91.30.70.70.40.60.2
Glucose0.20.30.6-0.80.80.80.40.40.70.60.50.30.00.50.50.80.60.7
Heart weight0.10.10.60.8-0.3-0.3-0.10.3-0.1-0.10.10.10.6-0.00.1-0.3-0.3-0.2
Left kidney weight0.30.95.81.40.20.21.10.60.50.21.01.02.40.71.00.10.10.1
Right kidney weight2.57.29.5-1.62.72.63.12.62.82.72.92.92.42.92.92.62.72.5
Tail length0.00.10.4-0.40.1-0.0-0.3-0.4-0.2-0.2-0.3-0.4-0.6-0.3-0.3-0.0-0.1-0.3
Length with tail1.86.68.0-1.72.72.62.82.52.72.42.82.82.22.82.72.52.62.4
Length without tail6.213.518.6-1.43.43.44.23.93.73.44.24.34.23.94.13.23.43.4
Liver weight, left1.82.93.4-1.01.71.71.81.61.81.81.81.71.51.81.81.61.71.6
Liver weight, right1.72.83.8-1.11.81.81.91.41.81.61.81.71.51.71.71.71.71.5
Parametrial fat weight1.83.56.21.8-1.9-2.0-1.2-2.5-2.0-2.1-1.8-1.6-0.7-1.9-1.9-2.0-2.0-2.1
Retroperitoneal fat weight0.41.43.51.9-1.3-1.4-0.4-1.4-1.2-1.3-0.8-0.60.7-1.0-0.9-1.4-1.3-1.3
Intraocular pressure7.110.015.51.4-3.0-3.0-3.9-3.2-3.1-2.9-3.5-3.8-3.5-3.3-3.3-2.9-2.9-2.9
Extensor digitorum longus weight4.819.123.6-3.24.54.44.94.34.54.44.74.83.44.74.54.34.44.3
Soleus weight0.72.13.1-1.31.61.51.81.11.41.51.51.70.91.51.41.51.51.4
Tibialis anterior weight2.06.79.0-2.62.82.73.02.62.62.72.62.61.32.72.42.62.72.6
Tibia length6.718.822.1-3.24.64.54.44.54.64.44.64.33.24.64.74.44.44.4
Number of licking bursts0.30.32.1-1.20.10.2-0.50.50.10.3-0.3-0.5-1.5-0.1-0.30.30.30.4
Food consumed during 24 hour testing period0.91.13.80.60.80.71.30.90.90.71.31.42.01.11.30.60.61.0
Times rat made contact with spout0.20.21.01.0-0.4-0.40.4-0.3-0.3-0.40.00.10.8-0.1-0.1-0.4-0.5-0.4
Mean time between licks in bursts0.20.30.70.3-0.5-0.6-0.8-0.4-0.5-0.4-0.6-0.7-0.6-0.6-0.6-0.5-0.5-0.4
Mean num. licks in bursts0.91.04.92.2-0.8-0.90.2-1.1-0.7-1.0-0.10.21.7-0.4-0.2-1.0-1.0-1.0
Std. dev. time between licks in bursts0.60.71.9-0.0-0.7-0.7-1.1-0.5-0.8-0.6-1.0-1.1-1.4-0.9-1.0-0.7-0.7-0.6
Water consumed over 24 hours0.10.10.30.5-0.1-0.20.5-0.1-0.1-0.20.10.40.60.00.0-0.2-0.2-0.1
Indifference point 0 sec1.62.63.21.0-1.5-1.6-1.2-1.6-1.8-1.8-1.7-1.6-1.3-1.7-1.8-1.7-1.7-1.8
Indifference point AUC0.20.20.8-0.2-0.3-0.3-0.5-0.6-0.4-0.4-0.5-0.5-0.9-0.4-0.5-0.3-0.3-0.2
Indifference point function ln k3.24.55.8-1.32.12.12.42.22.21.92.32.41.82.22.22.12.12.1
Indifference point function log k3.24.55.8-1.32.12.12.42.22.21.92.32.41.82.22.22.12.12.1
Delay discounting total patch changes 0 sec1.52.43.10.8-1.4-1.5-1.2-1.5-1.7-1.7-1.7-1.6-1.5-1.7-1.8-1.5-1.6-1.7
Delay discounting total patch changes 12 sec1.21.62.90.3-1.1-1.2-1.3-1.3-1.3-1.1-1.4-1.5-1.7-1.3-1.4-1.2-1.1-1.0
Delay discounting total patch changes 18 sec2.93.86.40.4-1.6-1.7-2.1-2.1-2.0-2.0-2.2-2.2-2.5-2.1-2.3-1.6-1.7-1.9
Delay discounting total patch changes 24 sec1.01.24.1-0.4-0.7-0.8-1.1-1.1-1.0-0.9-1.3-1.3-2.0-1.2-1.4-0.8-0.8-0.9
Delay discounting total patch changes 6 sec2.03.14.01.0-1.7-1.7-1.9-1.8-1.9-1.7-1.9-2.0-1.7-1.9-1.9-1.8-1.7-1.7
Delay discounting time to switch 0 sec2.33.55.51.0-2.0-1.9-2.3-1.4-2.0-1.5-2.1-2.2-2.0-2.0-2.0-1.9-1.8-1.6
Delay discounting water rate 0 sec3.45.47.9-1.62.52.52.81.72.42.12.52.72.02.52.42.52.32.1
Delay discounting water rate 12 sec3.55.26.5-1.72.42.52.32.12.52.12.42.41.72.42.42.52.32.2
Delay discounting water rate 18 sec0.50.61.0-0.60.80.81.00.60.80.80.80.90.70.80.70.80.70.7
Delay discounting water rate 24 sec3.34.65.9-2.12.22.22.32.02.22.22.12.21.02.22.12.32.22.4
Delay discounting water rate 6 sec3.95.67.3-1.62.42.52.72.22.52.42.52.61.92.52.42.52.32.4
Locomotor activity0.60.91.80.2-1.0-0.9-1.0-1.0-1.0-0.6-1.1-1.2-1.3-1.0-1.1-0.9-0.8-0.7
Locomotor testing distance1.93.24.30.8-1.8-1.7-1.9-1.6-1.9-1.6-2.1-2.1-2.0-2.0-2.1-1.7-1.7-1.6
Locomotor testing rearing1.52.36.00.0-1.4-1.3-1.8-0.8-1.5-1.2-1.8-2.0-2.4-1.6-1.8-1.3-1.2-1.1
Light reinforcement 11.83.39.7-0.3-1.3-1.3-2.2-1.5-1.7-1.3-2.2-2.4-3.1-2.0-2.2-1.3-1.3-1.4
Light reinforcement 20.60.81.30.3-0.8-0.8-1.1-0.8-0.9-0.8-1.0-1.2-1.0-1.0-1.0-0.8-0.7-0.7
Reaction time number correct0.71.01.9-0.70.80.90.91.41.01.11.01.00.61.01.11.00.91.1
Reaction time mean minus median9.011.613.73.4-3.6-3.6-3.5-3.3-3.6-3.5-3.4-3.5-1.8-3.5-3.3-3.7-3.6-3.5
Reaction time mean minus median AUC6.68.510.02.9-3.1-3.1-2.9-2.7-3.1-3.0-2.9-3.0-1.6-3.0-2.9-3.2-3.0-2.9
Reaction time num false alarms1.92.63.21.3-1.7-1.7-1.6-1.3-1.8-1.7-1.7-1.5-1.1-1.7-1.7-1.8-1.7-1.7
Reaction time num false alarms AUC3.14.35.31.9-2.2-2.3-2.1-1.7-2.3-2.2-2.1-2.0-1.1-2.1-2.1-2.3-2.3-2.1
Reaction time trials correct on left0.71.01.9-0.70.80.90.91.41.01.11.01.00.61.01.11.00.91.1
Reaction time trials on left0.50.71.4-0.60.60.80.71.20.80.90.80.80.50.90.90.80.70.9
Reaction time mean0.60.81.31.1-1.0-1.0-1.0-1.0-0.9-0.9-0.9-1.1-0.3-0.9-0.8-1.0-0.9-0.8
Reaction time mean AUC0.40.61.41.2-0.8-0.8-0.8-0.9-0.7-0.7-0.6-0.8-0.0-0.7-0.6-0.8-0.7-0.6
Median of all reaction times0.00.00.10.20.20.2-0.0-0.10.30.20.2-0.10.30.20.30.20.30.2
Reaction time omissions9.412.714.42.7-3.6-3.6-3.8-3.7-3.7-3.6-3.8-3.8-2.6-3.8-3.7-3.5-3.6-3.6
Reaction time false alarm rate2.63.74.61.7-1.9-2.1-1.8-1.8-2.1-2.1-1.9-1.8-1.0-2.0-2.0-2.1-2.1-2.1
Reaction time premature initiation rate4.05.47.10.9-2.2-2.2-2.5-2.3-2.4-2.1-2.6-2.7-2.7-2.5-2.6-2.2-2.2-2.1
Reaction time premature initiations2.13.04.90.5-1.8-1.7-1.9-1.5-1.8-1.5-2.0-2.0-2.2-1.8-2.0-1.6-1.7-1.4
Std. dev. reaction times6.58.910.02.9-3.1-3.1-3.0-3.0-3.1-3.0-3.0-3.1-1.7-3.1-2.9-3.2-3.0-3.0
Reaction time trials completed0.50.71.4-0.60.60.80.71.20.80.90.80.80.50.90.90.80.70.9
Reaction time trials AUC0.91.32.2-0.80.91.11.11.51.21.21.21.20.81.21.21.21.11.3
Social response proportion0.20.20.60.6-0.5-0.5-0.8-0.1-0.5-0.5-0.4-0.7-0.2-0.5-0.3-0.5-0.6-0.3
Social responses6.58.511.81.5-2.9-2.8-3.4-2.5-3.1-2.7-3.2-3.4-3.1-3.1-3.2-2.8-2.9-2.6
Social time0.40.52.11.4-0.7-0.8-0.8-0.5-0.6-0.5-0.4-0.70.4-0.5-0.2-0.9-0.7-0.7
Conditioned locomotion0.40.52.2-1.50.50.60.00.60.50.70.1-0.0-1.10.30.20.70.60.8
Cocaine response after cond. corrected0.60.73.51.9-0.5-0.60.2-0.7-0.4-0.8-0.00.21.6-0.3-0.1-0.7-0.8-0.9
Cocaine response after cond. not corrected1.51.64.22.0-1.3-1.4-1.1-1.2-1.2-1.4-0.9-0.90.5-1.1-0.9-1.4-1.5-1.5
Cocaine response before conditioning3.84.69.20.5-2.1-2.0-3.0-1.5-2.1-1.8-2.5-2.7-2.9-2.3-2.3-1.9-1.9-1.7
Saline control response0.00.00.2-0.00.10.0-0.50.20.10.1-0.0-0.2-0.20.00.1-0.00.00.2
Condit. Reinf. active minus inactive responses0.00.00.2-0.20.0-0.0-0.10.0-0.1-0.1-0.2-0.1-0.4-0.1-0.2-0.0-0.0-0.0
Condit. Reinf. active-inactive response ratio0.30.30.40.5-0.6-0.6-0.5-0.6-0.6-0.6-0.5-0.5-0.3-0.6-0.6-0.6-0.6-0.5
Condit. Reinf. active responses0.20.20.8-0.1-0.3-0.3-0.6-0.2-0.5-0.4-0.6-0.6-0.9-0.5-0.6-0.3-0.3-0.4
Condit. Reinf. inactive responses0.60.72.4-0.3-0.6-0.6-1.1-0.4-0.8-0.5-1.0-1.1-1.6-0.9-1.0-0.6-0.5-0.5
Condit. Reinf. lever presses0.00.00.00.1-0.0-0.1-0.20.2-0.1-0.0-0.1-0.2-0.2-0.1-0.1-0.2-0.10.1
Condit. Reinf. lever reinforcers received0.40.61.10.2-0.7-0.7-0.9-0.6-0.8-0.7-0.9-0.9-1.0-0.9-0.9-0.7-0.7-0.7
Pavlov. Cond. lever latency0.00.00.1-0.00.0-0.00.2-0.1-0.0-0.00.10.30.20.10.0-0.0-0.0-0.1
Pavlov. Cond. magazine entry latency0.60.71.0-0.60.90.90.61.00.90.90.90.70.50.91.00.90.91.0
Pavlov. Cond. change in total contacts1.11.62.4-0.31.31.21.11.51.41.31.41.01.31.41.51.21.21.4
Pavlov. Cond. index score0.40.50.7-0.40.80.70.40.80.80.70.70.40.40.70.80.70.70.8
Pavlov. Cond. latency score0.40.50.8-0.30.80.80.50.80.80.70.70.50.60.80.90.70.70.8
Pavlov. Cond. lever contacts0.10.10.40.4-0.3-0.3-0.6-0.3-0.3-0.3-0.4-0.6-0.3-0.4-0.3-0.3-0.3-0.3
Pavlov. Cond. magazine entry number2.02.53.21.4-1.7-1.7-1.2-1.8-1.7-1.7-1.5-1.3-0.7-1.6-1.7-1.7-1.7-1.8
Pavlov. Cond. intertrial magazine entries4.05.26.21.8-2.5-2.4-2.0-2.5-2.4-2.5-2.3-2.0-1.3-2.4-2.4-2.3-2.4-2.4
Pavlov. Cond. lever-magazine prob. diff.0.70.91.4-0.71.01.00.61.21.01.10.90.70.41.01.11.01.01.2
Pavlov. Cond. response bias0.00.00.20.0-0.0-0.0-0.40.1-0.10.0-0.2-0.4-0.3-0.1-0.0-0.1-0.00.1
Conditioned reinforcement - actives1.31.21.70.5-1.1-1.1-1.3-1.0-1.2-1.0-1.2-1.3-1.2-1.2-1.2-1.1-1.0-0.9
Conditioned reinforcement - inactives1.41.62.11.2-1.3-1.3-1.2-1.4-1.3-1.4-1.3-1.3-0.6-1.3-1.3-1.2-1.3-1.3
Conditioned locomotion0.20.31.4-0.5-0.3-0.3-0.6-0.3-0.4-0.3-0.6-0.6-1.2-0.5-0.6-0.2-0.2-0.2
Intermittent access intake day 1-15 change1.11.11.61.3-1.2-1.2-0.9-0.8-1.1-1.0-1.1-1.1-0.3-1.1-1.0-1.2-1.2-1.1
Intermittent access intake escalation0.90.91.71.3-1.1-1.0-0.7-0.7-1.0-0.9-0.9-0.9-0.0-1.0-0.9-1.1-1.1-1.0
Intermittent access intake escalation 21.21.21.81.3-1.2-1.2-1.0-0.9-1.2-1.0-1.1-1.1-0.3-1.2-1.1-1.3-1.2-1.2
Intermitt. access day 1 inactive lever presses2.62.87.4-0.3-1.3-1.4-2.0-1.7-1.6-1.4-1.9-1.9-2.7-1.7-1.9-1.3-1.3-1.3
Intermitt. access day 15 inactive lever presses0.91.01.60.2-0.8-0.9-1.0-1.2-1.0-1.0-1.1-1.1-1.3-1.0-1.2-0.7-0.9-0.9
Intermitt. access escalation Index0.20.20.6-0.2-0.3-0.3-0.4-0.2-0.3-0.3-0.5-0.6-0.8-0.4-0.5-0.3-0.3-0.1
Intermittent access day 1 total infusions1.21.31.71.0-1.2-1.2-1.1-1.1-1.2-1.3-1.2-1.2-0.8-1.2-1.2-1.2-1.2-1.1
Intermittent access day 15 total infusions2.02.22.81.2-1.6-1.5-1.5-1.3-1.6-1.5-1.6-1.7-1.1-1.6-1.6-1.5-1.5-1.4
Intermittent access terminal intake (last 3 days)2.22.42.91.3-1.6-1.6-1.5-1.5-1.6-1.6-1.7-1.7-1.1-1.7-1.7-1.5-1.6-1.5
Intermittent access total infusions2.02.22.81.1-1.5-1.5-1.5-1.4-1.6-1.6-1.6-1.7-1.2-1.6-1.6-1.5-1.5-1.4
Intermittent access day 1 locomotion0.60.72.7-0.5-0.5-0.5-1.0-0.8-0.7-0.7-1.0-1.0-1.6-0.8-1.0-0.3-0.4-0.4
Intermittent access day 15 total locomotion0.70.83.3-0.7-0.5-0.5-1.0-0.7-0.7-0.6-1.1-1.1-1.8-0.9-1.1-0.3-0.4-0.5
Intermittent access total locomotion1.92.27.4-0.6-1.0-1.0-1.7-1.4-1.3-1.2-1.8-1.8-2.7-1.5-1.8-0.9-1.0-1.1
Intermittent access standard deviation0.50.50.80.9-0.9-0.8-0.6-0.5-0.8-0.6-0.7-0.7-0.2-0.8-0.7-0.9-0.8-0.7
Cocaine induced anxiety1.21.41.9-1.21.21.21.01.31.21.41.11.10.51.21.11.21.31.3
Post-drug Anxiety4.34.75.5-1.72.22.32.12.32.32.22.32.21.42.32.32.32.22.2
Baseline Anxiety0.91.01.6-0.31.01.01.20.81.10.71.11.21.21.11.11.00.90.8
Lifetime Intake1.61.82.31.0-1.4-1.4-1.4-1.3-1.4-1.5-1.4-1.5-1.0-1.4-1.4-1.3-1.3-1.3
Incentive Sensitization - Responses0.10.10.3-0.50.40.30.30.20.30.60.30.20.00.30.20.40.40.3
Incentive Sensitization - Breakpoint0.10.10.2-0.40.30.20.10.10.20.50.10.1-0.20.20.10.20.30.2
Progressive ratio test 1 active lever presses2.82.94.10.6-1.6-1.6-1.9-1.7-1.7-1.7-1.9-2.0-2.0-1.8-1.9-1.5-1.5-1.5
Progressive ratio test 1 breakpoint2.52.63.70.5-1.5-1.5-1.7-1.6-1.6-1.6-1.8-1.9-1.9-1.7-1.8-1.4-1.4-1.4
Progressive ratio test 1 inactive lever presses2.32.53.40.5-1.4-1.5-1.7-1.6-1.6-1.7-1.8-1.8-1.8-1.7-1.8-1.3-1.5-1.5
Progressive ratio test 2 active lever presses1.31.33.0-0.0-1.0-1.0-1.3-1.1-1.2-0.9-1.4-1.5-1.7-1.2-1.4-0.9-0.9-0.9
Progressive ratio test 2 breakpoint1.71.94.00.1-1.2-1.3-1.5-1.4-1.4-1.1-1.6-1.8-2.0-1.5-1.6-1.1-1.1-1.2
Progressive ratio test 2 inactive lever presses2.02.33.70.4-1.5-1.5-1.7-1.4-1.6-1.3-1.7-1.8-1.9-1.6-1.7-1.4-1.3-1.3
Total sessions with >9 infusions0.20.30.40.5-0.4-0.4-0.5-0.5-0.5-0.6-0.6-0.7-0.3-0.6-0.6-0.4-0.4-0.5
Short access day 1 total inactive lever presses0.80.81.30.5-0.9-0.9-1.0-0.8-0.9-0.9-1.0-1.1-0.9-1.0-1.0-0.8-0.8-0.9
Short access day 10 total inactive lever presses0.40.42.4-0.8-0.3-0.3-0.8-0.4-0.5-0.2-0.7-0.7-1.6-0.5-0.7-0.3-0.2-0.2
Short access day 1 total infusions0.00.00.20.20.20.20.20.10.2-0.10.10.10.40.10.10.20.10.1
Short access day 10 total infusions0.50.60.70.9-0.8-0.8-0.7-0.6-0.8-0.8-0.7-0.8-0.2-0.8-0.7-0.8-0.8-0.8
Short access total infusions0.10.10.20.3-0.4-0.4-0.3-0.2-0.3-0.5-0.4-0.4-0.2-0.4-0.4-0.4-0.3-0.3
Short access day 1 locomotion0.10.10.5-0.70.30.20.20.10.20.10.10.0-0.40.10.00.30.40.3
Short access day 10 total locomotion0.40.52.9-1.70.40.3-0.4-0.20.10.0-0.3-0.3-1.7-0.1-0.40.50.40.2
Short access total locomotion0.20.31.8-1.10.10.0-0.4-0.2-0.1-0.2-0.4-0.5-1.3-0.2-0.40.10.20.1
Compulsive drug intake0.50.51.00.10.70.60.80.70.70.60.80.91.00.70.80.60.50.6
One hour access (0.3 mA shock)0.10.20.30.5-0.5-0.4-0.5-0.1-0.4-0.2-0.4-0.5-0.1-0.4-0.3-0.5-0.4-0.3
One hour access (shock baseline)0.00.00.00.1-0.1-0.1-0.10.0-0.1-0.0-0.1-0.20.0-0.1-0.1-0.10.0-0.1
Number of responses in last shaping day0.50.51.1-1.00.80.70.70.90.70.70.50.5-0.20.60.40.70.80.8
Context. condit. distance diff. score0.30.40.6-0.50.70.70.80.60.70.70.70.60.40.70.60.70.70.7
Locomotion velocity, session 10.60.71.4-0.0-0.9-0.8-0.7-0.8-0.9-0.8-1.0-0.8-1.2-0.9-1.1-0.7-0.7-0.8
Locomotion distance, session 13.54.66.32.2-2.3-2.3-1.8-2.5-2.2-2.4-2.0-1.9-0.7-2.2-2.1-2.3-2.3-2.3
Locomotion velocity, session 20.40.40.70.6-0.8-0.8-0.4-0.7-0.7-0.8-0.6-0.5-0.1-0.6-0.6-0.8-0.8-0.7
Locomotion distance, session 22.84.05.42.0-2.2-2.2-1.8-2.3-2.1-2.3-1.9-1.8-0.7-2.0-1.9-2.2-2.2-2.1
Locomotion velocity, session 33.74.35.41.9-2.1-2.2-1.9-2.3-2.2-2.2-2.1-2.0-1.1-2.1-2.1-2.2-2.2-2.2
Locomotion distance, session 35.15.56.52.0-2.4-2.4-2.4-2.6-2.4-2.4-2.4-2.4-1.5-2.5-2.4-2.4-2.4-2.4
Stereotopy head waving bouts, day 31.21.52.2-1.41.11.21.01.31.31.31.11.10.31.21.21.31.31.5
Stereotopy head waving duration, day 30.50.61.0-1.00.60.70.60.80.80.80.70.60.10.70.70.80.81.0
Locomotion velocity, session 70.00.00.2-0.1-0.0-0.1-0.2-0.4-0.2-0.1-0.3-0.2-0.3-0.2-0.3-0.1-0.1-0.2
Locomotion distance, session 70.91.21.70.5-0.8-0.9-1.2-1.2-1.1-1.0-1.2-1.3-1.2-1.2-1.3-0.9-0.9-1.1
Stereotopy head waving bouts, day 71.41.62.7-1.61.21.31.11.31.31.41.11.10.01.21.11.41.31.6
Stereotopy head waving duration, day 71.72.03.1-1.71.41.41.51.41.41.51.31.40.31.41.31.51.51.7
Locomotion velocity, session 80.00.00.2-0.00.00.00.4-0.00.10.10.20.30.30.10.10.10.10.0
Locomotion distance, session 81.52.23.31.7-1.6-1.6-1.2-1.8-1.6-1.7-1.3-1.2-0.4-1.4-1.4-1.6-1.6-1.6
Degree of sensitization distance0.80.91.1-1.01.11.00.90.91.00.90.90.90.40.90.91.01.00.9
Degree of sensitization stereotypy0.70.72.0-1.40.80.80.80.90.80.90.60.7-0.40.80.60.90.91.0
Condit. Reinf. active minus inactive responses0.30.31.21.1-0.6-0.6-0.4-0.8-0.5-0.6-0.3-0.30.5-0.4-0.3-0.6-0.6-0.5
Condit. Reinf. active-inactive response ratio0.10.21.20.8-0.0-0.10.3-0.10.1-0.10.30.41.10.20.3-0.1-0.10.0
Condit. Reinf. active responses0.70.91.41.2-1.1-1.1-0.9-1.1-0.9-1.0-0.8-0.8-0.1-0.9-0.8-1.0-1.0-0.9
Condit. Reinf. inactive responses2.22.63.60.8-1.6-1.6-1.9-1.3-1.7-1.5-1.8-1.9-1.7-1.7-1.8-1.5-1.5-1.5
Incentive salience index mean0.00.10.40.50.00.00.0-0.10.10.00.20.10.60.20.30.00.10.1
Condit. Reinf. lever presses0.20.30.50.00.50.50.40.40.60.50.60.40.70.60.70.60.60.6
Time in familiar zone, hab. session 10.60.61.41.2-0.9-0.9-0.3-0.8-0.8-0.9-0.6-0.50.2-0.7-0.6-0.9-0.9-0.9
Time in novel zone, hab. session 10.90.82.6-1.61.01.10.21.00.91.10.50.3-0.70.70.61.11.11.0
Total zone transitions, hab. session 10.20.30.50.0-0.5-0.5-0.7-0.7-0.6-0.6-0.6-0.7-0.7-0.6-0.6-0.5-0.5-0.5
Total locomotion distance, hab. session 10.00.10.10.3-0.3-0.2-0.3-0.4-0.2-0.3-0.1-0.20.1-0.2-0.1-0.2-0.2-0.2
Locomotion velocity, hab. session 10.00.00.00.1-0.1-0.1-0.2-0.2-0.0-0.1-0.0-0.10.1-0.1-0.0-0.1-0.1-0.0
Time in familiar zone, hab. session 20.10.10.70.60.10.10.10.10.2-0.00.30.20.90.20.40.0-0.0-0.0
Time in novel zone, hab. session 20.30.31.9-1.30.10.2-0.10.2-0.00.3-0.3-0.2-1.4-0.1-0.40.30.30.3
Total zone transitions, hab. session 20.40.51.21.1-0.7-0.8-0.3-1.1-0.7-0.9-0.5-0.40.3-0.6-0.5-0.8-0.8-0.9
Total locomotion distance, hab. session 20.30.41.11.0-0.7-0.7-0.4-1.0-0.6-0.8-0.4-0.40.3-0.5-0.4-0.7-0.7-0.7
Locomotion velocity, hab. session 20.20.30.91.0-0.6-0.6-0.2-0.9-0.4-0.6-0.2-0.20.6-0.4-0.2-0.6-0.6-0.6
Novel to familiar place preference ratio2.12.33.0-1.71.71.71.11.71.61.71.31.20.21.51.41.71.61.7
Novelty place preference1.71.82.9-1.71.61.50.81.51.41.51.10.9-0.11.21.21.51.51.5
Time in novel zone, NPP test1.61.63.3-1.81.51.50.71.51.31.50.90.8-0.41.11.01.51.41.5
Total zone transitions, NPP test1.42.13.41.8-1.5-1.6-1.2-1.9-1.4-1.6-1.2-1.2-0.1-1.4-1.2-1.5-1.5-1.6
Total locomotion distance, NPP test2.23.04.21.6-1.8-1.8-1.9-2.0-1.7-1.8-1.7-1.8-0.9-1.8-1.6-1.8-1.8-1.8
Locomotion velocity, NPP test1.31.92.91.5-1.5-1.5-1.4-1.7-1.3-1.5-1.2-1.3-0.3-1.3-1.2-1.4-1.5-1.4
Pavlov. Cond. lever latency0.00.00.1-0.3-0.00.00.20.0-0.1-0.0-0.10.2-0.3-0.0-0.10.0-0.0-0.0
Pavlov. Cond. magazine entry latency0.10.21.01.0-0.3-0.3-0.2-0.4-0.3-0.4-0.1-0.10.7-0.2-0.0-0.4-0.4-0.3
Pavlov. Cond. change in total contacts0.10.10.10.10.20.2-0.00.30.30.20.30.10.30.30.40.20.20.3
Pavlov. Cond. index score0.10.20.30.00.40.40.20.30.40.40.50.30.50.40.50.40.40.4
Pavlov. Cond. latency score0.10.10.30.10.30.30.10.20.40.30.40.10.60.30.50.30.30.3
Pavlov. Cond. lever contacts0.20.20.50.6-0.4-0.4-0.7-0.5-0.4-0.4-0.4-0.6-0.1-0.4-0.3-0.4-0.4-0.4
Pavlov. Cond. magazine entry number0.00.10.4-0.60.20.10.20.20.10.20.00.1-0.40.10.00.20.20.1
Pavlov. Cond. intertrial magazine entries0.50.61.00.9-1.0-0.9-0.6-0.9-0.8-0.8-0.7-0.7-0.2-0.8-0.7-0.8-0.8-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.00.60.60.60.60.70.60.80.60.90.70.80.60.60.6
Pavlov. Cond. response bias0.10.20.90.9-0.3-0.4-0.4-0.4-0.3-0.5-0.2-0.30.5-0.3-0.1-0.4-0.4-0.4
Bone: apparent density7.111.716.4-1.13.43.33.63.23.63.13.93.94.13.74.03.13.23.1
Bone surface8.915.720.5-1.74.03.94.23.84.13.74.54.54.24.34.53.73.73.7
Bone volume6.410.714.6-1.33.33.23.43.13.53.13.73.73.63.63.83.13.13.0
Bone: connectivity density4.87.512.9-0.52.72.53.02.52.82.43.23.23.63.03.32.42.42.3
Bone: cortical apparent density0.30.31.3-0.2-0.4-0.4-0.8-0.4-0.5-0.4-0.7-0.8-1.1-0.6-0.7-0.4-0.4-0.2
Bone: cortical area9.013.616.5-2.13.83.74.13.63.83.64.04.03.34.04.03.63.63.5
Bone: cortical porosity1.21.33.00.1-1.0-0.9-1.7-0.8-1.1-0.9-1.3-1.4-1.7-1.2-1.3-0.9-0.8-0.9
Bone: cortical porosity1.61.73.60.2-1.2-1.1-1.9-1.0-1.2-1.0-1.5-1.6-1.9-1.4-1.5-1.0-1.0-1.1
Bone: cortical thickness3.66.07.7-1.12.42.42.72.22.62.32.82.72.52.72.82.32.32.3
Bone: cortical thickness0.20.30.80.30.50.40.60.50.50.40.60.60.90.50.60.40.40.4
Bone: cortical tissue density0.40.51.5-0.2-0.5-0.5-0.9-0.5-0.6-0.5-0.9-0.9-1.2-0.7-0.8-0.5-0.5-0.3
Bone: elastic displacement4.14.76.01.1-2.2-2.1-2.4-2.1-2.3-2.1-2.4-2.4-2.2-2.3-2.4-2.1-2.0-2.1
Bone: elastic work0.00.00.2-0.1-0.1-0.1-0.3-0.0-0.1-0.1-0.3-0.3-0.4-0.2-0.2-0.1-0.0-0.1
Bone: endosteal estimation6.714.417.4-2.93.93.94.04.03.93.84.04.22.74.03.93.83.83.9
Bone: endosteal perimeter6.513.315.5-2.63.73.73.83.93.83.63.93.92.73.93.83.63.63.8
Bone: final force8.013.117.4-1.63.63.54.23.43.73.44.14.23.93.94.13.43.43.4
Bone: final moment7.913.117.7-1.43.53.54.23.43.73.34.14.24.03.94.13.33.43.3
Bone: marrow area6.714.317.4-3.03.83.94.04.03.93.84.04.22.64.03.93.83.83.9
Bone: maximum diameter4.37.89.6-2.02.92.93.12.92.92.83.03.12.13.02.92.82.82.7
Bone: maximum force11.119.323.8-2.54.54.44.84.34.64.24.84.94.04.74.84.34.34.3
Bone: maximum moment10.919.023.9-2.44.44.34.84.34.54.24.84.94.14.74.84.24.24.2
Bone: minimum diameter8.315.417.5-3.04.04.04.04.24.14.04.14.12.74.14.14.04.04.1
Bone: periosteal estimation10.822.126.6-3.14.84.85.14.84.94.65.15.23.85.05.04.64.64.6
Bone: periosteal perimeter9.014.919.4-2.03.93.84.33.84.03.74.34.43.74.24.23.73.73.7
Bone: post-yield work7.410.012.1-2.83.33.33.23.33.23.23.33.51.93.33.23.23.23.3
Bone: stiffness13.721.726.9-2.74.84.75.14.54.84.55.15.24.25.05.14.54.64.5
Bone: tissue strength0.50.50.8-0.70.80.80.60.90.80.80.70.60.30.70.80.80.80.8
Bone: trabecular number3.45.213.40.22.11.92.52.02.31.72.82.83.72.52.81.71.81.7
Bone: trabecular spacing1.01.35.5-0.7-0.9-0.8-1.1-0.8-1.0-0.7-1.4-1.4-2.4-1.2-1.5-0.7-0.7-0.6
Bone: trabecular thickness0.30.41.61.3-0.5-0.6-0.6-0.6-0.6-0.7-0.4-0.50.4-0.5-0.3-0.7-0.7-0.6
Bone: trabecular tissue density0.10.11.0-0.70.00.1-0.40.1-0.10.1-0.4-0.4-1.0-0.2-0.30.10.10.2
Breakpoint value in progressive ratio session0.10.10.4-0.20.30.30.20.60.40.60.40.30.20.40.40.30.30.5
Distance traveled before self-admin0.70.82.4-0.3-0.7-0.7-1.0-0.9-0.8-0.6-1.0-1.1-1.5-0.9-1.0-0.6-0.6-0.6
Distance traveled after self-admin0.20.30.50.7-0.5-0.6-0.3-0.5-0.5-0.7-0.4-0.4-0.1-0.5-0.4-0.5-0.5-0.6
Delta time in closed arm before/after self-admin0.30.31.71.1-0.3-0.10.30.40.0-0.20.30.41.30.20.4-0.4-0.2-0.1
Delta time in open arm before/after self-admin3.23.14.30.6-1.6-1.6-2.0-2.0-1.8-1.6-2.0-2.0-2.1-1.8-2.0-1.5-1.6-1.6
Diff in mean of infusions in LGA sessions1.01.11.8-0.20.90.91.01.11.01.31.21.11.31.11.20.81.01.0
Extinction: sum of active levers before priming0.40.40.7-0.80.80.70.60.30.70.80.60.60.20.70.60.70.70.6
Active lever presses in extinction session 60.30.30.70.20.30.30.60.70.40.30.60.70.90.60.60.20.30.5
Delta distance traveled before/after self-admin0.20.21.21.1-0.1-0.10.40.1-0.0-0.40.30.31.10.10.2-0.2-0.2-0.3
Delta ambulatory time before/after self-admin0.10.10.50.70.0-0.10.30.0-0.0-0.30.20.20.70.00.1-0.1-0.2-0.2
Time in closed arm before self-admin1.82.03.6-1.91.51.51.11.61.41.71.21.20.01.41.21.61.51.7
Time in closed arm after self-admin0.40.40.8-0.50.60.60.60.90.70.70.70.70.50.70.70.50.70.7
Time in open arm before self-admin0.90.91.2-0.61.11.11.10.91.00.91.01.00.91.00.91.01.00.8
Time in open arm after self-admin0.20.20.4-0.0-0.2-0.3-0.5-0.5-0.3-0.4-0.5-0.5-0.7-0.4-0.5-0.1-0.3-0.3
Sum of active levers in priming session hrs 5-60.10.10.30.2-0.4-0.4-0.5-0.2-0.4-0.3-0.4-0.4-0.3-0.4-0.4-0.3-0.4-0.4
Time to tail flick, vehicle, before self-admin1.41.41.81.1-1.3-1.3-1.2-1.2-1.3-1.1-1.2-1.2-0.7-1.2-1.2-1.3-1.3-1.2
Time to tail flick, vehicle, after self-admin0.50.62.0-1.40.80.80.20.70.71.00.40.3-0.60.60.40.80.81.0
Time to tail flick, test, before self-admin0.50.51.10.4-0.7-0.6-0.9-1.1-0.6-0.5-0.7-0.8-0.5-0.7-0.7-0.6-0.6-0.7
Time to tail flick, test, after self-admin0.10.10.2-0.20.30.40.40.40.40.30.40.40.50.30.40.40.30.2
Delta time to tail flick, vehicle, before/after SA0.70.60.8-0.90.80.90.60.80.90.80.70.70.20.80.80.90.90.9
Delta time to tail flick, test, before/after SA0.30.30.5-0.40.60.60.70.70.50.30.50.60.40.50.50.60.40.4
Ambulatory time before self-admin2.93.05.50.3-1.5-1.6-2.0-1.8-1.7-1.4-2.0-2.1-2.3-1.8-2.0-1.5-1.5-1.5
Ambulatory time after self-admin1.21.32.30.3-0.9-1.0-1.2-1.2-1.1-1.0-1.3-1.3-1.5-1.2-1.3-1.0-1.0-1.0
Total heroin consumption2.83.45.2-2.31.91.91.61.71.92.21.61.60.21.81.62.02.12.1
Area under the delay curve1.01.12.70.01.00.91.30.91.00.81.21.21.61.11.20.80.90.8
Delay disc. indifference point, 0s delay1.51.62.0-1.21.41.31.40.81.41.21.31.40.81.31.31.41.41.2
Delay disc. indifference point, 16s delay1.31.31.8-0.81.31.21.31.11.21.11.21.21.01.21.21.21.21.1
Delay disc. indifference point, 2s delay1.01.11.4-0.81.01.01.11.01.11.11.11.10.81.11.21.01.11.2
Delay disc. indifference point, 24s delay1.51.41.6-0.81.21.21.31.21.21.21.31.30.91.31.31.21.21.2
Delay disc. indifference point, 4s delay0.30.32.30.80.20.10.70.40.30.00.60.61.50.40.50.10.20.1
Delay disc. indifference point, 8s delay2.62.75.3-0.21.51.52.01.61.71.31.91.92.31.71.81.41.51.4
Delay discount exponential model param0.90.92.5-0.1-0.8-0.8-1.2-0.9-0.9-0.7-1.1-1.1-1.6-1.0-1.1-0.7-0.8-0.8
Delay discount hyperbolic model param0.80.82.3-0.1-0.8-0.7-1.2-0.8-0.9-0.7-1.1-1.1-1.5-0.9-1.0-0.7-0.8-0.7
Fecal boli incidents, locomotor time 12.62.98.12.9-1.8-1.8-0.9-1.7-1.6-2.0-1.2-1.11.0-1.5-1.2-1.9-1.8-2.0
Change in fecal boli incidents, locomotor task1.01.01.5-1.01.01.00.90.71.01.21.01.00.41.01.01.01.11.2
Time >=10cm from walls, locomotor time 10.30.31.60.40.40.40.80.30.50.20.60.61.30.50.60.40.30.1
Bouts of movement, locomotor time 10.10.10.80.50.20.20.5-0.20.30.00.30.30.90.20.20.30.1-0.2
Total resting periods, locomotor time 10.20.20.80.9-0.3-0.4-0.1-0.7-0.3-0.5-0.3-0.20.5-0.4-0.3-0.3-0.4-0.7
Rest time, locomotor task time 10.30.30.80.9-0.5-0.5-0.2-0.8-0.4-0.7-0.4-0.40.4-0.5-0.4-0.5-0.5-0.7
Distance moved, locomotor task time 10.10.10.5-0.5-0.1-0.1-0.40.4-0.20.2-0.2-0.2-0.7-0.1-0.1-0.10.00.2
Vertical activity count, locomotor time 11.01.02.40.10.80.81.11.30.90.91.11.21.51.01.20.70.80.8
Time >=10cm from walls, locomotor time 20.30.31.00.5-0.5-0.6-0.5-1.0-0.6-0.4-0.6-0.6-0.3-0.6-0.6-0.6-0.5-0.6
Bouts of movement, locomotor time 23.13.34.2-1.91.91.91.91.51.92.01.81.80.81.91.81.92.01.9
Total resting periods, locomotor time 23.43.64.5-2.02.02.02.01.62.02.11.91.90.82.01.82.02.11.9
Rest time, locomotor task time 20.10.10.50.10.40.40.50.20.40.20.40.40.70.30.40.40.30.0
Distance moved, locomotor task time 20.20.30.50.1-0.5-0.5-0.7-0.3-0.5-0.4-0.6-0.6-0.7-0.5-0.5-0.5-0.5-0.2
Vertical activity count, locomotor time 20.10.10.2-0.30.40.40.50.50.30.20.30.40.20.30.30.40.30.3
Weight adjusted by age3.03.34.8-1.91.91.91.81.71.92.01.81.70.61.91.81.92.02.2
Seeking ratio, delayed vs. immediate footshock0.30.42.61.10.10.10.60.50.30.10.60.61.60.40.60.0-0.00.0
Locomotion in novel chamber0.70.81.0-0.90.90.91.00.71.00.90.91.00.61.00.91.01.01.0
Locomotion in novel chamber post-restriction0.20.30.7-0.60.70.60.80.10.60.20.50.60.40.50.40.60.60.3
Progressive ratio0.10.10.30.6-0.3-0.30.1-0.1-0.3-0.6-0.1-0.10.4-0.2-0.2-0.4-0.3-0.4
Food seeking constrained by brief footshock0.10.10.40.4-0.2-0.20.0-0.6-0.3-0.6-0.3-0.20.1-0.3-0.4-0.2-0.4-0.5
Seeking ratio, punishment vs. effort0.00.10.2-0.50.30.30.0-0.20.20.30.10.0-0.30.10.10.40.10.2
Run reversals in cocaine runway, females0.10.10.4-0.3-0.00.0-0.50.1-0.10.1-0.3-0.3-0.7-0.2-0.2-0.0-0.00.1
Run reversals in cocaine runway, males1.21.21.70.5-1.0-1.0-1.3-1.2-1.1-1.1-1.2-1.2-1.1-1.1-1.2-1.0-1.0-1.0
Latency to leave start box in cocaine runway0.00.00.1-0.3-0.0-0.0-0.1-0.1-0.0-0.1-0.1-0.1-0.2-0.1-0.1-0.00.0-0.2
Latency to leave start box in cocaine runway, F1.41.63.00.1-1.1-1.1-1.5-1.2-1.2-1.1-1.4-1.5-1.7-1.3-1.4-1.1-1.1-1.2
Latency to leave start box in cocaine runway, M1.61.62.7-0.41.11.11.61.21.21.01.41.61.71.31.41.11.10.9
Cd content in liver0.30.30.40.5-0.5-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.4-0.6-0.6-0.6-0.6-0.5
Co content in liver0.00.00.30.1-0.1-0.1-0.40.0-0.1-0.1-0.2-0.5-0.3-0.2-0.2-0.1-0.1-0.1
Cu content in liver1.01.21.6-0.51.01.11.30.91.21.11.21.21.21.21.21.11.01.1
Fe content in liver0.10.10.20.3-0.3-0.3-0.3-0.4-0.3-0.2-0.3-0.5-0.2-0.3-0.3-0.3-0.3-0.3
K content in liver0.60.61.70.10.50.51.20.50.60.50.90.91.30.80.70.50.50.5
Mg content in liver0.00.00.30.4-0.1-0.10.2-0.10.0-0.10.10.10.50.00.1-0.1-0.1-0.1
Mn content in liver0.10.10.2-0.50.20.20.40.00.20.30.20.4-0.10.20.10.30.30.2
Na content in liver0.00.00.1-0.30.00.00.30.10.10.20.10.2-0.00.1-0.00.10.10.2
Rb content in liver0.00.00.1-0.1-0.1-0.1-0.0-0.3-0.1-0.2-0.2-0.3-0.4-0.2-0.3-0.1-0.1-0.2
Se content in liver0.50.61.01.0-0.8-0.8-0.6-0.7-0.8-0.8-0.7-0.7-0.1-0.7-0.7-0.8-0.8-0.9
Sr content in liver0.70.70.9-0.60.90.91.00.50.90.80.90.90.60.90.90.80.90.8
Zn content in liver0.60.71.3-0.1-0.7-0.8-0.6-0.9-0.8-0.8-0.9-0.9-1.2-0.8-1.0-0.7-0.7-0.8