Hub : Genes

Capn13

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000032375	0.18	0.07	0.0e+00	0.26	0.28	0.29	0.29	6.6e-29	1.9e-31	9.1e-33	2.2e-32
2	Adipose	intron excision ratio	chr6:22136486:22138323	0.03	0.02	4.5e-03	0.01	0.01	0.01	0.01	6.0e-02	9.2e-03	3.9e-02	1.8e-02
3	Adipose	mRNA stability	ENSRNOG00000032375	0.06	0.04	2.3e-06	0.06	0.05	0.06	0.06	5.8e-07	3.0e-06	1.0e-06	9.0e-07
4	Eye	gene expression	ENSRNOG00000032375	0.58	0.16	2.9e-04	-0.02	0.08	-0.01	0	8.0e-01	2.4e-02	4.1e-01	3.2e-01
5	LHb	alternative polyA	ENSRNOT00000047853	0.3	0.15	3.3e-03	0.11	0.06	0.06	0.08	1.3e-03	1.2e-02	1.3e-02	6.6e-03
6	LHb	alternative polyA	ENSRNOT00000111503	0.34	0.15	1.6e-03	0.08	0.08	0.07	0.08	6.7e-03	7.4e-03	9.2e-03	5.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	0.1	0.3	0.7	-0.8	-0.5	-0.6	-0.1	0.3	-0.3
BMI without tail	0.1	0.3	0.9	-1.0	-0.3	-0.9	0.1	0.2	-0.2
Body weight	0.4	1.5	3.4	-1.8	-1.1	-1.0	0.1	1.3	-1.3
Epididymis fat weight	1.7	3.9	9.4	1.1	-0.5	1.6	0.5	3.1	-3.1
Glucose	0.5	0.8	1.5	0.6	0.8	-0.7	1.2	0.9	-0.9
Heart weight	3.0	4.3	9.6	1.2	-0.2	2.1	0.4	3.1	-3.1
Left kidney weight	0.5	1.5	2.8	1.0	1.5	-1.7	1.3	-0.9	0.9
Right kidney weight	0.1	0.4	0.6	0.0	0.2	-0.8	0.6	0.8	-0.8
Tail length	0.1	0.3	0.5	-0.4	0.0	-0.4	0.6	0.7	-0.7
Length with tail	0.3	1.2	3.0	-0.8	-0.8	0.1	0.2	1.7	-1.7
Length without tail	0.1	0.1	0.3	-0.3	-0.4	0.1	-0.1	0.5	-0.5
Liver weight, left	0.2	0.4	0.9	-0.2	-0.2	-0.6	0.1	0.9	-0.9
Liver weight, right	1.7	2.7	7.3	0.2	-1.2	0.7	-0.2	2.7	-2.7
Parametrial fat weight	0.5	0.9	1.7	-0.1	-0.9	0.7	-0.8	1.3	-1.3
Retroperitoneal fat weight	3.8	12.5	33.5	1.3	-0.6	2.0	1.5	5.8	-5.8
Intraocular pressure	1.4	2.0	4.5	-0.2	-1.8	2.0	-2.1	0.4	-0.4
Extensor digitorum longus weight	1.3	5.2	9.7	-1.8	0.9	-2.7	0.6	-3.1	3.1
Soleus weight	1.3	3.8	8.3	-2.9	-0.6	-1.6	-0.8	-2.4	2.4
Tibialis anterior weight	0.8	2.7	4.8	-1.5	0.8	-2.0	0.4	-2.2	2.2
Tibia length	0.6	1.7	3.3	0.2	0.7	-1.8	1.7	1.3	-1.3
Number of licking bursts	0.4	0.5	1.9	-1.4	-0.7	-0.6	-0.4	0.1	-0.1
Food consumed during 24 hour testing period	0.1	0.1	0.3	-0.3	-0.5	0.5	-0.3	0.3	-0.3
Times rat made contact with spout	1.5	1.7	4.6	-0.5	0.4	-0.8	0.0	-2.1	2.1
Mean time between licks in bursts	0.2	0.2	0.5	0.1	-0.6	0.5	-0.7	0.3	-0.3
Mean num. licks in bursts	1.6	1.9	3.0	1.5	1.5	-0.2	0.9	-1.7	1.7
Std. dev. time between licks in bursts	0.7	0.8	1.1	-0.7	-1.1	1.0	-0.9	0.9	-0.9
Water consumed over 24 hours	0.4	0.4	1.0	-0.4	0.4	-0.5	0.2	-1.0	1.0
Indifference point 0 sec	0.1	0.2	0.4	0.7	0.5	0.1	0.3	-0.4	0.4
Indifference point AUC	1.3	1.5	2.7	-0.5	0.8	-1.5	0.6	-1.6	1.6
Indifference point function ln k	0.4	0.5	1.2	0.9	-0.2	1.1	-0.5	0.7	-0.7
Indifference point function log k	0.4	0.5	1.2	0.9	-0.2	1.1	-0.5	0.7	-0.7
Delay discounting total patch changes 0 sec	0.0	0.0	0.0	0.2	0.1	0.1	-0.0	-0.1	0.1
Delay discounting total patch changes 12 sec	0.1	0.1	0.1	-0.3	-0.3	-0.1	-0.3	-0.2	0.2
Delay discounting total patch changes 18 sec	0.7	0.9	1.3	0.1	1.1	-1.1	1.1	-0.9	0.9
Delay discounting total patch changes 24 sec	0.0	0.1	0.2	0.2	0.2	-0.1	0.5	-0.1	0.1
Delay discounting total patch changes 6 sec	0.1	0.2	0.5	-0.7	-0.4	-0.1	-0.5	-0.4	0.4
Delay discounting time to switch 0 sec	0.2	0.3	0.6	-0.7	-0.2	0.0	-0.3	-0.8	0.8
Delay discounting water rate 0 sec	0.1	0.2	0.2	0.5	-0.2	0.3	-0.5	0.4	-0.4
Delay discounting water rate 12 sec	1.2	1.8	3.1	0.5	-1.1	1.4	-1.1	1.8	-1.8
Delay discounting water rate 18 sec	0.6	0.7	1.1	-0.6	-1.0	0.4	-0.9	1.0	-1.0
Delay discounting water rate 24 sec	0.7	1.0	1.8	-0.7	-1.4	0.2	-0.8	1.2	-1.2
Delay discounting water rate 6 sec	0.8	1.2	1.8	0.1	-1.0	1.2	-1.0	1.4	-1.4
Locomotor activity	0.2	0.3	1.1	0.2	-0.2	1.0	-0.6	0.4	-0.4
Locomotor testing distance	0.1	0.1	0.5	-0.1	0.0	0.7	-0.4	-0.1	0.1
Locomotor testing rearing	0.2	0.3	0.5	-0.6	0.2	-0.7	0.2	-0.6	0.6
Light reinforcement 1	2.0	3.7	7.6	-1.1	1.4	-2.8	1.0	-2.2	2.2
Light reinforcement 2	0.4	0.6	1.5	-0.6	0.6	-1.2	0.1	-0.8	0.8
Reaction time number correct	0.1	0.2	0.4	-0.0	-0.2	0.5	-0.3	0.7	-0.7
Reaction time mean minus median	1.0	1.2	3.0	1.7	1.6	0.2	1.3	-0.2	0.2
Reaction time mean minus median AUC	0.7	0.9	2.7	1.6	0.8	1.0	0.6	0.5	-0.5
Reaction time num false alarms	2.8	3.9	8.7	-2.4	-2.8	0.9	-3.0	-0.1	0.1
Reaction time num false alarms AUC	2.9	4.1	8.7	-2.7	-2.8	0.6	-3.0	-0.2	0.2
Reaction time trials correct on left	0.1	0.2	0.4	-0.0	-0.2	0.5	-0.3	0.7	-0.7
Reaction time trials on left	0.2	0.2	0.5	0.0	-0.2	0.5	-0.3	0.7	-0.7
Reaction time mean	0.7	0.9	2.1	1.5	0.6	1.0	0.5	1.0	-1.0
Reaction time mean AUC	0.7	0.9	1.5	1.2	0.4	1.0	0.4	1.1	-1.1
Median of all reaction times	0.8	1.1	1.7	1.3	0.2	1.3	0.2	1.3	-1.3
Reaction time omissions	0.3	0.4	1.3	0.5	-0.3	1.2	-0.5	0.6	-0.6
Reaction time false alarm rate	1.8	2.5	5.4	-2.3	-2.2	0.0	-2.2	-0.5	0.5
Reaction time premature initiation rate	0.7	1.0	2.5	-1.6	-0.6	-1.2	-0.4	-0.8	0.8
Reaction time premature initiations	0.3	0.5	1.7	-1.3	-0.7	-0.4	-0.6	-0.2	0.2
Std. dev. reaction times	0.8	1.1	3.1	1.8	1.1	0.9	0.9	0.5	-0.5
Reaction time trials completed	0.2	0.2	0.5	0.0	-0.2	0.5	-0.3	0.7	-0.7
Reaction time trials AUC	0.1	0.1	0.2	0.2	0.1	0.3	-0.1	0.4	-0.4
Social response proportion	0.4	0.4	0.7	0.1	0.5	-0.8	0.4	-0.8	0.8
Social responses	1.1	1.5	4.6	0.3	1.5	-1.4	2.1	-0.1	0.1
Social time	1.6	2.1	3.9	1.7	2.0	-1.0	1.9	-0.7	0.7
Conditioned locomotion	1.1	1.3	2.7	-0.8	-0.6	0.0	-1.1	-1.6	1.6
Cocaine response after cond. corrected	0.3	0.3	0.6	0.5	0.2	0.3	-0.5	-0.8	0.8
Cocaine response after cond. not corrected	0.6	0.7	1.8	0.3	0.4	-0.3	-0.3	-1.3	1.3
Cocaine response before conditioning	0.9	1.1	2.3	-0.3	0.8	-1.5	0.8	-1.2	1.2
Saline control response	1.0	1.4	3.0	-0.2	1.3	-1.7	1.4	-0.8	0.8
Condit. Reinf. active minus inactive responses	0.8	1.0	2.6	-1.6	-1.3	0.3	-1.1	0.1	-0.1
Condit. Reinf. active-inactive response ratio	0.8	0.9	2.1	-1.4	-1.2	0.1	-1.2	-0.1	0.1
Condit. Reinf. active responses	0.3	0.4	1.1	-1.0	-0.8	0.2	-0.6	0.3	-0.3
Condit. Reinf. inactive responses	0.0	0.1	0.2	-0.5	-0.3	0.1	-0.2	-0.1	0.1
Condit. Reinf. lever presses	0.3	0.4	1.1	-1.1	-0.6	-0.8	-0.4	-0.1	0.1
Condit. Reinf. lever reinforcers received	0.3	0.4	1.1	-1.1	-0.8	0.3	-0.6	0.3	-0.3
Pavlov. Cond. lever latency	0.4	0.5	1.1	1.1	0.6	0.4	0.8	0.6	-0.6
Pavlov. Cond. magazine entry latency	0.5	0.6	1.6	-0.2	0.4	-1.3	0.2	-0.9	0.9
Pavlov. Cond. change in total contacts	1.0	1.4	2.8	-1.6	-1.7	0.3	-1.6	0.4	-0.4
Pavlov. Cond. index score	0.2	0.3	0.4	-0.7	-0.2	-0.6	-0.4	-0.5	0.5
Pavlov. Cond. latency score	0.1	0.1	0.4	-0.5	-0.1	-0.6	-0.2	-0.3	0.3
Pavlov. Cond. lever contacts	0.8	1.1	3.0	-1.7	-1.4	-0.2	-1.3	-0.2	0.2
Pavlov. Cond. magazine entry number	0.2	0.2	0.8	0.6	-0.0	0.9	0.0	0.2	-0.2
Pavlov. Cond. intertrial magazine entries	1.3	1.6	3.0	1.7	0.6	1.1	1.0	1.5	-1.5
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.2	-0.5	-0.3	-0.4	-0.5	-0.3	0.3
Pavlov. Cond. response bias	0.8	1.1	3.1	-1.8	-1.0	-0.7	-1.1	-0.6	0.6
Conditioned reinforcement - actives	1.9	1.9	4.9	0.4	1.4	-2.2	1.4	-1.0	1.0
Conditioned reinforcement - inactives	2.5	2.8	6.5	0.5	2.1	-2.6	2.1	-0.7	0.7
Conditioned locomotion	2.1	2.5	5.4	1.1	2.2	-1.8	2.3	-0.4	0.4
Intermittent access intake day 1-15 change	0.3	0.3	0.8	0.4	-0.9	0.3	-0.8	0.4	-0.4
Intermittent access intake escalation	0.5	0.5	1.2	0.4	-1.1	0.5	-1.0	0.4	-0.4
Intermittent access intake escalation 2	0.7	0.7	1.4	0.8	-0.7	0.4	-0.3	1.2	-1.2
Intermitt. access day 1 inactive lever presses	0.3	0.3	0.9	-0.3	0.5	-0.4	0.9	0.4	-0.4
Intermitt. access day 15 inactive lever presses	2.9	3.2	6.9	1.8	2.6	-1.6	2.5	-0.5	0.5
Intermitt. access escalation Index	0.3	0.3	0.5	-0.5	-0.7	-0.5	-0.6	-0.3	0.3
Intermittent access day 1 total infusions	2.2	2.5	7.4	-0.8	1.2	-2.7	0.9	-1.5	1.5
Intermittent access day 15 total infusions	0.7	0.8	3.0	-0.5	0.1	-1.7	-0.2	-0.9	0.9
Intermittent access terminal intake (last 3 days)	1.3	1.4	5.5	0.0	0.7	-2.3	0.6	-1.0	1.0
Intermittent access total infusions	1.8	2.0	6.6	-0.4	1.0	-2.6	0.7	-1.3	1.3
Intermittent access day 1 locomotion	2.7	2.8	7.7	-0.3	1.7	-2.8	1.8	-1.2	1.2
Intermittent access day 15 total locomotion	1.9	2.0	5.7	-0.2	1.2	-2.4	1.1	-1.3	1.3
Intermittent access total locomotion	1.4	1.6	5.4	0.0	1.2	-2.3	1.4	-0.6	0.6
Intermittent access standard deviation	0.2	0.2	0.7	0.1	0.3	-0.8	0.5	0.2	-0.2
Cocaine induced anxiety	0.3	0.4	0.9	0.5	0.7	-0.6	1.0	-0.2	0.2
Post-drug Anxiety	0.5	0.5	1.5	1.2	0.9	0.0	0.9	0.1	-0.1
Baseline Anxiety	0.2	0.2	0.3	-0.1	-0.3	0.1	-0.6	-0.6	0.6
Lifetime Intake	2.5	2.7	7.7	-0.1	1.3	-2.8	0.9	-1.8	1.8
Incentive Sensitization - Responses	0.3	0.3	1.1	0.1	0.1	-1.0	0.3	0.5	-0.5
Incentive Sensitization - Breakpoint	0.3	0.3	1.0	-0.0	0.0	-1.0	0.3	0.5	-0.5
Progressive ratio test 1 active lever presses	1.7	1.7	6.7	-0.2	1.3	-2.6	1.4	-0.3	0.3
Progressive ratio test 1 breakpoint	1.8	1.9	7.7	-0.3	1.2	-2.8	1.4	-0.2	0.2
Progressive ratio test 1 inactive lever presses	1.3	1.4	4.6	-0.3	1.1	-2.1	1.1	-0.8	0.8
Progressive ratio test 2 active lever presses	0.7	0.8	3.4	0.1	0.8	-1.8	0.8	-0.2	0.2
Progressive ratio test 2 breakpoint	0.7	0.8	3.6	0.2	0.8	-1.9	0.7	-0.3	0.3
Progressive ratio test 2 inactive lever presses	1.0	1.1	2.9	0.6	1.2	-1.7	1.0	-0.7	0.7
Total sessions with >9 infusions	0.3	0.3	0.9	0.1	0.4	-0.9	0.1	-0.5	0.5
Short access day 1 total inactive lever presses	1.9	2.1	6.9	-0.4	1.3	-2.6	1.4	-0.9	0.9
Short access day 10 total inactive lever presses	1.8	2.0	4.1	2.0	2.0	0.4	1.9	0.4	-0.4
Short access day 1 total infusions	1.3	1.4	4.1	-0.2	0.9	-2.0	0.7	-1.2	1.2
Short access day 10 total infusions	2.5	2.8	5.1	0.0	1.3	-2.3	0.6	-2.2	2.2
Short access total infusions	2.5	2.8	6.3	0.5	1.6	-2.5	1.0	-1.8	1.8
Short access day 1 locomotion	2.1	2.2	5.4	0.1	1.5	-2.3	1.5	-1.4	1.4
Short access day 10 total locomotion	1.6	1.8	3.2	0.3	1.5	-1.8	1.6	-1.2	1.2
Short access total locomotion	2.1	2.1	4.4	0.8	1.8	-2.1	1.9	-0.6	0.6
Compulsive drug intake	0.8	0.8	2.2	0.6	-0.2	1.5	-0.1	1.0	-1.0
One hour access (0.3 mA shock)	0.9	1.1	2.2	0.7	0.8	-1.5	0.5	-1.2	1.2
One hour access (shock baseline)	1.5	1.7	5.6	-0.4	0.6	-2.4	0.4	-1.4	1.4
Number of responses in last shaping day	0.9	0.9	1.4	-1.2	-1.2	0.0	-0.8	1.0	-1.0
Context. condit. distance diff. score	0.0	0.0	0.1	-0.2	-0.3	-0.2	0.1	0.2	-0.2
Locomotion velocity, session 1	0.8	0.8	1.2	1.1	1.1	-0.7	0.7	-0.9	0.9
Locomotion distance, session 1	0.3	0.4	0.7	-0.4	-0.3	0.0	-0.8	-0.8	0.8
Locomotion velocity, session 2	0.0	0.0	0.1	0.1	-0.0	0.2	-0.3	-0.2	0.2
Locomotion distance, session 2	0.0	0.1	0.2	-0.2	-0.3	0.2	-0.5	-0.0	0.0
Locomotion velocity, session 3	1.0	1.2	3.1	0.0	0.6	-0.6	-0.2	-1.8	1.8
Locomotion distance, session 3	0.9	1.0	2.1	-0.9	0.1	-0.9	-0.0	-1.5	1.5
Stereotopy head waving bouts, day 3	1.1	1.3	2.6	0.3	1.0	-1.0	0.6	-1.6	1.6
Stereotopy head waving duration, day 3	0.4	0.5	0.7	0.5	0.7	-0.7	0.3	-0.9	0.9
Locomotion velocity, session 7	1.9	2.1	3.7	-1.9	-0.6	-1.3	-0.9	-1.7	1.7
Locomotion distance, session 7	0.8	1.0	2.1	-1.4	-1.4	0.3	-1.3	-0.3	0.3
Stereotopy head waving bouts, day 7	0.1	0.1	0.5	0.7	0.3	0.3	0.2	-0.1	0.1
Stereotopy head waving duration, day 7	0.5	0.6	1.2	0.8	0.7	-0.1	0.2	-1.1	1.1
Locomotion velocity, session 8	1.3	1.6	2.8	0.4	1.0	-1.6	0.6	-1.7	1.7
Locomotion distance, session 8	0.2	0.3	0.8	-0.9	-0.8	-0.2	-0.6	-0.1	0.1
Degree of sensitization distance	1.2	1.2	2.0	-0.6	-1.4	0.9	-1.1	1.2	-1.2
Degree of sensitization stereotypy	0.3	0.3	0.8	-0.2	-0.6	0.9	-0.6	0.4	-0.4
Condit. Reinf. active minus inactive responses	0.2	0.2	0.5	-0.7	-0.5	-0.2	-0.2	0.3	-0.3
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.4	0.2	0.6	-0.5	0.6	-0.3	0.3
Condit. Reinf. active responses	0.7	0.8	2.2	-1.5	-1.2	0.0	-1.1	-0.1	0.1
Condit. Reinf. inactive responses	1.0	1.2	2.7	-1.2	-1.6	0.5	-1.7	-0.0	0.0
Incentive salience index mean	0.4	0.5	1.3	-1.2	-0.8	-0.1	-0.8	-0.3	0.3
Condit. Reinf. lever presses	1.0	1.3	2.7	-1.5	-1.3	0.6	-1.6	-0.7	0.7
Time in familiar zone, hab. session 1	0.2	0.2	0.4	0.6	0.5	0.3	0.4	0.1	-0.1
Time in novel zone, hab. session 1	0.5	0.5	1.2	-0.1	-0.5	0.5	-0.1	1.1	-1.1
Total zone transitions, hab. session 1	0.6	0.9	1.9	0.1	-0.4	1.4	-0.2	1.3	-1.3
Total locomotion distance, hab. session 1	0.3	0.5	1.0	0.5	0.4	0.4	0.6	1.0	-1.0
Locomotion velocity, hab. session 1	0.1	0.2	0.4	-0.1	0.3	-0.2	0.5	0.6	-0.6
Time in familiar zone, hab. session 2	1.6	1.7	2.5	1.1	1.5	-0.9	0.8	-1.6	1.6
Time in novel zone, hab. session 2	1.2	1.2	2.4	-0.7	-1.1	0.8	-0.4	1.5	-1.5
Total zone transitions, hab. session 2	0.1	0.1	0.4	0.3	0.0	0.6	-0.3	-0.3	0.3
Total locomotion distance, hab. session 2	0.1	0.1	0.2	-0.0	0.4	-0.2	0.5	-0.1	0.1
Locomotion velocity, hab. session 2	0.1	0.1	0.1	-0.2	0.3	-0.2	0.3	-0.3	0.3
Novel to familiar place preference ratio	2.1	2.2	4.7	0.5	-0.7	1.8	-0.2	2.2	-2.2
Novelty place preference	2.3	2.4	5.0	0.6	-0.8	1.8	-0.2	2.2	-2.2
Time in novel zone, NPP test	2.4	2.5	5.1	0.5	-0.8	1.9	-0.3	2.3	-2.3
Total zone transitions, NPP test	0.2	0.3	1.1	-1.0	-0.4	0.1	-0.5	-0.4	0.4
Total locomotion distance, NPP test	0.1	0.1	0.7	-0.9	-0.3	0.2	-0.2	0.1	-0.1
Locomotion velocity, NPP test	0.2	0.3	0.6	-0.8	0.3	-0.5	0.2	-0.6	0.6
Pavlov. Cond. lever latency	0.7	0.9	2.4	0.5	-0.1	0.3	0.4	1.6	-1.6
Pavlov. Cond. magazine entry latency	0.1	0.2	0.8	-0.9	-0.2	-0.3	-0.1	-0.2	0.2
Pavlov. Cond. change in total contacts	0.1	0.1	0.5	-0.7	-0.3	-0.2	-0.2	0.1	-0.1
Pavlov. Cond. index score	0.2	0.2	0.5	-0.7	-0.1	-0.2	-0.2	-0.6	0.6
Pavlov. Cond. latency score	0.1	0.2	0.5	-0.7	-0.2	-0.0	-0.3	-0.5	0.5
Pavlov. Cond. lever contacts	0.4	0.5	1.0	-0.8	-0.1	-0.4	-0.3	-1.0	1.0
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	0.4	-0.0	0.3	-0.1	0.3	-0.3
Pavlov. Cond. intertrial magazine entries	0.5	0.6	1.3	0.4	-0.3	0.2	-0.9	-1.2	1.2
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.4	0.9	-0.9	-0.2	-0.2	-0.4	-0.8	0.8
Pavlov. Cond. response bias	0.4	0.4	1.2	-0.3	0.3	-0.4	-0.0	-1.1	1.1
Bone: apparent density	1.5	2.6	6.5	1.0	1.1	-0.5	0.1	-2.5	2.5
Bone surface	0.9	1.7	3.5	1.1	1.2	-0.2	0.5	-1.9	1.9
Bone volume	1.0	1.7	3.4	1.2	1.2	-0.4	0.5	-1.9	1.9
Bone: connectivity density	1.5	2.3	6.3	0.8	0.9	-0.1	-0.2	-2.5	2.5
Bone: cortical apparent density	0.8	1.0	1.9	1.0	1.4	-1.2	1.2	-0.6	0.6
Bone: cortical area	0.0	0.1	0.1	-0.2	0.1	-0.3	0.1	-0.4	0.4
Bone: cortical porosity	2.1	2.2	6.3	0.3	-1.4	2.5	-2.2	-0.4	0.4
Bone: cortical porosity	2.2	2.4	7.9	0.3	-1.4	2.8	-2.1	-0.1	0.1
Bone: cortical thickness	0.1	0.1	0.3	0.1	-0.3	0.3	-0.2	0.6	-0.6
Bone: cortical thickness	0.5	0.6	1.8	-0.4	-1.0	0.8	-1.3	-0.2	0.2
Bone: cortical tissue density	0.9	1.1	2.0	1.1	1.4	-1.2	1.3	-0.5	0.5
Bone: elastic displacement	0.2	0.2	0.7	-0.6	-0.6	0.1	-0.8	-0.2	0.2
Bone: elastic work	0.3	0.4	1.0	-0.6	-0.6	0.2	-1.0	-0.6	0.6
Bone: endosteal estimation	0.1	0.3	0.8	-0.2	0.4	-0.3	0.2	-0.9	0.9
Bone: endosteal perimeter	0.1	0.3	0.6	-0.3	0.6	-0.5	0.8	-0.4	0.4
Bone: final force	0.4	0.6	1.3	1.1	0.5	0.9	-0.2	-0.8	0.8
Bone: final moment	0.4	0.6	1.1	1.0	0.4	0.7	-0.2	-0.9	0.9
Bone: marrow area	0.1	0.3	0.7	-0.3	0.3	-0.3	0.2	-0.9	0.9
Bone: maximum diameter	0.4	0.6	0.8	-0.0	0.9	-0.8	0.8	-0.9	0.9
Bone: maximum force	0.1	0.1	0.5	0.5	0.2	0.7	0.0	-0.1	0.1
Bone: maximum moment	0.0	0.1	0.2	0.4	0.1	0.4	-0.1	-0.3	0.3
Bone: minimum diameter	0.1	0.2	0.6	0.0	0.4	-0.2	0.3	-0.8	0.8
Bone: periosteal estimation	0.1	0.3	0.7	-0.3	0.4	-0.4	0.3	-0.8	0.8
Bone: periosteal perimeter	0.1	0.1	0.7	-0.8	-0.3	0.1	-0.1	0.1	-0.1
Bone: post-yield work	0.2	0.2	0.5	-0.3	0.5	-0.6	0.7	-0.1	0.1
Bone: stiffness	0.1	0.1	0.5	0.0	-0.4	0.7	-0.3	0.3	-0.3
Bone: tissue strength	0.2	0.2	0.3	0.2	-0.4	0.5	-0.4	0.4	-0.4
Bone: trabecular number	1.7	2.6	6.1	1.2	1.3	-0.4	0.3	-2.5	2.5
Bone: trabecular spacing	1.0	1.3	2.8	-0.8	-0.9	0.8	-0.5	1.7	-1.7
Bone: trabecular thickness	0.5	0.6	1.2	0.5	0.4	-0.8	0.3	-1.1	1.1
Bone: trabecular tissue density	0.2	0.3	0.7	0.6	0.8	-0.4	0.8	-0.1	0.1
Breakpoint value in progressive ratio session	0.4	0.5	1.1	0.2	1.0	-0.8	1.1	-0.1	0.1
Distance traveled before self-admin	0.7	0.8	1.9	-1.4	-0.6	-0.5	0.0	1.1	-1.1
Distance traveled after self-admin	1.0	1.2	1.7	-1.3	-1.2	0.4	-0.7	1.3	-1.3
Delta time in closed arm before/after self-admin	1.2	1.1	3.9	0.1	-0.9	2.0	-1.0	0.7	-0.7
Delta time in open arm before/after self-admin	2.4	2.3	4.5	0.7	2.1	-1.5	1.9	-1.2	1.2
Diff in mean of infusions in LGA sessions	1.3	1.4	3.3	1.5	1.8	-0.7	1.6	-0.0	0.0
Extinction: sum of active levers before priming	1.1	1.1	2.7	-1.7	-1.4	0.6	-1.3	0.1	-0.1
Active lever presses in extinction session 6	1.9	1.8	3.6	1.6	1.9	-1.0	1.6	-0.8	0.8
Delta distance traveled before/after self-admin	0.4	0.5	1.2	1.1	0.5	0.4	0.6	0.6	-0.6
Delta ambulatory time before/after self-admin	0.1	0.2	0.5	0.7	0.4	0.1	0.3	-0.2	0.2
Time in closed arm before self-admin	0.5	0.6	2.6	-0.0	0.2	-1.6	0.8	0.4	-0.4
Time in closed arm after self-admin	1.0	1.1	2.9	-0.3	-0.6	-0.2	0.2	1.7	-1.7
Time in open arm before self-admin	1.6	1.7	4.1	-0.9	-1.6	1.6	-2.0	0.3	-0.3
Time in open arm after self-admin	0.6	0.7	1.6	-0.2	0.8	-0.5	0.2	-1.3	1.3
Sum of active levers in priming session hrs 5-6	0.5	0.5	0.8	0.9	0.9	0.2	0.7	-0.7	0.7
Time to tail flick, vehicle, before self-admin	1.6	1.6	2.5	-0.6	-1.6	0.7	-1.3	1.6	-1.6
Time to tail flick, vehicle, after self-admin	1.0	1.1	1.9	0.7	0.7	0.2	1.3	1.4	-1.4
Time to tail flick, test, before self-admin	0.1	0.1	0.2	-0.2	-0.1	-0.2	0.0	0.4	-0.4
Time to tail flick, test, after self-admin	0.7	0.7	1.4	-0.9	0.0	-1.2	0.9	0.8	-0.8
Delta time to tail flick, vehicle, before/after SA	0.5	0.5	1.1	0.6	1.0	-0.0	1.0	-0.5	0.5
Delta time to tail flick, test, before/after SA	0.7	0.7	1.7	-0.6	0.6	-1.3	0.8	-0.7	0.7
Ambulatory time before self-admin	1.0	1.0	2.4	-1.5	-0.3	-0.9	0.3	1.2	-1.2
Ambulatory time after self-admin	0.5	0.5	1.0	-0.9	-0.4	-0.3	0.3	1.0	-1.0
Total heroin consumption	1.2	1.5	3.6	1.2	1.9	-0.6	1.5	-0.8	0.8
Area under the delay curve	0.9	0.9	2.0	-0.8	-0.4	0.0	-0.9	-1.4	1.4
Delay disc. indifference point, 0s delay	1.2	1.3	1.9	-0.3	-1.3	1.4	-1.3	1.0	-1.0
Delay disc. indifference point, 16s delay	0.8	0.8	2.0	-0.4	-0.2	0.5	-0.8	-1.4	1.4
Delay disc. indifference point, 2s delay	0.5	0.6	1.2	0.0	-0.5	0.1	-1.0	-1.1	1.1
Delay disc. indifference point, 24s delay	2.5	2.4	6.2	-1.1	0.0	-0.6	-0.7	-2.5	2.5
Delay disc. indifference point, 4s delay	0.9	0.9	2.5	0.5	0.2	-0.2	-0.6	-1.6	1.6
Delay disc. indifference point, 8s delay	1.0	1.0	1.8	-1.2	-0.5	-0.3	-0.8	-1.3	1.3
Delay discount exponential model param	1.2	1.3	3.0	0.8	0.4	0.0	0.9	1.7	-1.7
Delay discount hyperbolic model param	1.1	1.2	3.0	0.6	0.3	0.1	0.8	1.7	-1.7
Fecal boli incidents, locomotor time 1	1.8	1.9	5.5	-0.3	-1.4	2.3	-1.7	0.7	-0.7
Change in fecal boli incidents, locomotor task	1.2	1.2	2.4	-1.0	-1.1	-0.1	-0.2	1.5	-1.5
Time >=10cm from walls, locomotor time 1	4.2	4.2	8.3	-0.9	-2.8	2.3	-2.9	1.2	-1.2
Bouts of movement, locomotor time 1	1.1	1.2	2.3	-1.5	-0.7	-0.5	-1.0	-1.2	1.2
Total resting periods, locomotor time 1	1.3	1.4	2.2	-1.4	-1.0	0.1	-1.5	-1.3	1.3
Rest time, locomotor task time 1	0.8	0.9	2.1	-0.5	-1.1	1.4	-1.4	-0.2	0.2
Distance moved, locomotor task time 1	0.7	0.7	1.2	0.9	0.9	-1.0	1.1	0.5	-0.5
Vertical activity count, locomotor time 1	0.1	0.1	0.2	0.3	0.2	-0.5	0.5	0.4	-0.4
Time >=10cm from walls, locomotor time 2	1.1	1.1	2.1	1.2	0.0	1.1	0.4	1.4	-1.4
Bouts of movement, locomotor time 2	2.6	2.7	5.5	-1.6	-2.3	1.5	-2.0	1.1	-1.1
Total resting periods, locomotor time 2	1.9	2.0	4.1	-1.5	-2.0	1.0	-1.6	0.9	-0.9
Rest time, locomotor task time 2	0.4	0.4	0.9	-0.1	0.4	-0.7	0.4	-1.0	1.0
Distance moved, locomotor task time 2	0.9	1.0	1.9	1.1	1.2	-0.9	1.4	0.5	-0.5
Vertical activity count, locomotor time 2	0.6	0.6	2.0	1.4	0.8	0.3	0.8	0.4	-0.4
Weight adjusted by age	0.5	0.6	1.3	-0.2	0.2	-0.8	-0.4	-1.1	1.1
Seeking ratio, delayed vs. immediate footshock	1.7	1.9	4.0	0.9	1.9	-1.6	2.0	-0.4	0.4
Locomotion in novel chamber	0.9	1.1	1.6	1.3	1.0	0.2	1.1	1.1	-1.1
Locomotion in novel chamber post-restriction	1.4	1.7	4.2	0.2	-0.7	1.0	-0.4	2.1	-2.1
Progressive ratio	1.3	1.5	2.8	1.2	1.7	-0.9	1.6	-0.9	0.9
Food seeking constrained by brief footshock	1.6	2.0	5.1	0.4	0.8	-1.0	-0.1	-2.3	2.3
Seeking ratio, punishment vs. effort	1.3	1.6	4.5	-1.1	-1.7	0.8	-2.1	-0.0	0.0
Run reversals in cocaine runway, females	0.1	0.1	0.2	-0.2	0.1	-0.2	0.4	0.5	-0.5
Run reversals in cocaine runway, males	0.3	0.3	1.1	-1.0	-0.6	-0.4	-0.4	0.1	-0.1
Latency to leave start box in cocaine runway	0.6	0.7	1.5	0.4	0.6	-0.7	0.2	-1.2	1.2
Latency to leave start box in cocaine runway, F	1.2	1.3	3.3	-0.6	0.1	-0.8	-0.4	-1.8	1.8
Latency to leave start box in cocaine runway, M	0.2	0.2	0.6	0.8	0.4	-0.2	0.6	0.2	-0.2
Cd content in liver	0.7	0.8	2.3	0.1	-0.7	1.5	-0.6	0.8	-0.8
Co content in liver	2.4	2.8	5.8	-2.4	-1.8	0.6	-2.3	-1.1	1.1
Cu content in liver	0.2	0.3	0.4	-0.6	-0.6	-0.1	-0.5	-0.5	0.5
Fe content in liver	0.8	0.9	3.2	1.8	1.1	0.3	0.8	-0.3	0.3
K content in liver	0.2	0.2	0.8	-0.1	0.6	-0.5	0.9	0.1	-0.1
Mg content in liver	1.8	1.9	3.4	0.7	1.9	-1.4	1.8	-0.9	1.0
Mn content in liver	0.5	0.6	1.0	-0.1	0.9	-0.2	0.9	-1.0	1.0
Na content in liver	1.6	1.7	3.3	0.8	1.8	-1.4	1.8	-0.8	0.8
Rb content in liver	0.5	0.6	1.3	-0.0	0.6	-0.8	0.2	-1.1	1.1
Se content in liver	0.8	1.0	2.0	0.7	1.3	-1.2	1.4	-0.4	0.4
Sr content in liver	0.5	0.5	0.8	-0.8	-0.5	-0.6	0.0	0.9	-0.9
Zn content in liver	0.7	0.7	2.5	-0.3	0.7	-1.6	1.0	-0.3	0.3