Hub : Genes

Izumo4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000031950 0.37 0.15 0.0e+00 0.27 0.27 0.27 0.27 8.1e-30 5.1e-30 4.9e-30 3.3e-30
2 BLA gene expression ENSRNOG00000031950 0.26 0.17 1.8e-04 0.07 0.06 0.07 0.07 1.5e-04 3.1e-04 8.2e-05 1.9e-04
3 BLA isoform ratio ENSRNOT00000113785 0.09 0.06 4.6e-06 0.1 0.1 0.09 0.1 4.1e-06 4.0e-06 1.2e-05 3.4e-06
4 BLA isoform ratio ENSRNOT00000115800 0.06 0.04 3.7e-04 0.08 0.07 0.07 0.07 5.5e-05 1.6e-04 9.3e-05 2.1e-04
5 BLA intron excision ratio chr7:9008225:9008446 0.04 0.03 5.7e-03 0.03 0.03 0.03 0.03 6.7e-03 9.1e-03 8.1e-03 1.7e-02
6 Brain gene expression ENSRNOG00000031950 0.19 0.11 1.4e-07 0.04 0.07 0.06 0.07 7.0e-05 2.2e-07 1.2e-06 2.7e-07
7 NAcc gene expression ENSRNOG00000031950 0.47 0.18 1.0e-05 0.08 0.05 0.06 0.07 1.4e-06 9.4e-05 3.5e-05 3.3e-06
8 OFC isoform ratio ENSRNOT00000115800 0.15 0.11 1.8e-03 0.12 0.1 0.1 0.11 9.5e-04 2.8e-03 2.8e-03 1.4e-03
9 PL gene expression ENSRNOG00000031950 0.28 0.13 7.6e-08 0.07 0.1 0.11 0.11 4.2e-06 3.5e-08 9.5e-09 8.6e-09
10 PL isoform ratio ENSRNOT00000113785 0.04 0.03 7.8e-04 0.04 0.04 0.03 0.04 4.6e-04 5.9e-04 1.4e-03 5.3e-04
11 PL isoform ratio ENSRNOT00000115800 0.05 0.05 9.6e-04 0.03 0.03 0.04 0.04 1.5e-03 3.0e-03 7.0e-04 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail5.919.223.74.84.4-4.54.5-4.63.64.84.91.4-4.74.8
BMI without tail2.65.57.72.72.7-1.91.9-2.12.82.72.71.8-2.02.3
Body weight1.04.35.32.32.0-2.22.1-2.31.82.32.30.6-2.22.2
Epididymis fat weight0.10.30.9-0.30.20.8-0.81.00.1-0.1-0.20.80.8-0.3
Glucose1.21.82.31.41.3-1.41.5-1.41.11.51.50.5-1.41.4
Heart weight0.30.40.9-0.30.10.8-0.80.80.4-0.2-0.20.80.9-0.5
Left kidney weight0.10.31.0-0.5-0.70.1-0.1-0.1-0.9-0.6-0.6-1.00.1-0.4
Right kidney weight1.33.64.5-2.1-1.92.0-2.01.8-1.6-2.1-2.1-0.72.0-2.1
Tail length2.47.411.1-2.9-2.23.2-3.23.1-1.4-2.7-2.80.33.3-3.1
Length with tail1.86.78.7-2.9-2.72.5-2.62.4-2.2-2.9-2.9-1.12.6-2.9
Length without tail0.40.82.7-0.8-1.2-0.0-0.00.0-1.4-0.9-1.0-1.60.0-0.6
Liver weight, left2.64.15.62.42.3-1.91.9-1.81.82.42.40.9-1.82.3
Liver weight, right1.52.53.51.71.5-1.81.7-1.80.91.71.7-0.0-1.81.9
Parametrial fat weight0.30.61.1-0.8-0.51.0-1.00.8-0.2-0.8-0.80.31.0-1.1
Retroperitoneal fat weight0.31.01.51.21.2-1.00.9-0.81.01.21.20.4-0.81.1
Intraocular pressure0.60.93.60.61.20.5-0.50.51.60.70.71.90.50.2
Extensor digitorum longus weight4.417.722.64.64.5-4.04.1-4.14.14.74.71.9-4.24.5
Soleus weight7.622.127.65.14.3-5.25.2-5.23.75.04.90.8-5.35.1
Tibialis anterior weight1.03.44.91.91.7-2.02.1-2.11.52.02.00.4-2.21.9
Tibia length0.82.23.4-1.5-1.21.7-1.71.7-0.9-1.5-1.50.01.9-1.6
Number of licking bursts0.50.52.50.50.90.2-0.10.21.10.60.61.60.10.3
Food consumed during 24 hour testing period0.50.60.90.80.7-0.80.9-0.70.80.80.80.4-1.00.7
Times rat made contact with spout0.40.51.20.70.9-0.30.3-0.31.10.80.81.1-0.30.6
Mean time between licks in bursts3.34.66.9-2.2-1.62.6-2.62.6-1.1-2.1-2.10.52.6-2.4
Mean num. licks in bursts0.10.10.40.0-0.2-0.30.3-0.4-0.2-0.0-0.0-0.6-0.30.1
Std. dev. time between licks in bursts1.21.42.4-1.4-1.50.8-0.70.8-1.2-1.4-1.4-1.10.9-1.4
Water consumed over 24 hours0.40.51.20.4-0.1-1.01.0-1.0-0.20.30.3-1.0-1.10.5
Indifference point 0 sec0.10.10.30.30.0-0.50.5-0.5-0.10.20.2-0.1-0.50.4
Indifference point AUC0.60.71.3-0.9-0.51.1-1.11.0-0.5-0.7-0.80.21.0-0.9
Indifference point function ln k0.20.20.40.50.3-0.60.6-0.50.60.40.40.3-0.60.4
Indifference point function log k0.20.20.40.50.3-0.60.6-0.50.60.40.40.3-0.60.4
Delay discounting total patch changes 0 sec0.10.10.20.30.1-0.40.3-0.40.10.20.20.1-0.40.3
Delay discounting total patch changes 12 sec0.60.81.71.01.3-0.30.4-0.41.11.11.11.2-0.40.9
Delay discounting total patch changes 18 sec0.91.21.6-1.1-0.91.2-1.31.3-0.8-1.1-1.10.11.2-1.2
Delay discounting total patch changes 24 sec0.10.10.1-0.2-0.20.3-0.30.3-0.3-0.2-0.20.20.3-0.2
Delay discounting total patch changes 6 sec0.20.30.5-0.7-0.60.6-0.60.5-0.7-0.7-0.6-0.10.6-0.6
Delay discounting time to switch 0 sec1.11.73.11.10.3-1.71.7-1.8-0.60.80.8-1.5-1.61.5
Delay discounting water rate 0 sec0.50.73.20.20.90.5-0.40.51.60.60.51.80.3-0.2
Delay discounting water rate 12 sec1.72.66.01.72.1-0.80.8-0.82.41.81.92.1-0.81.3
Delay discounting water rate 18 sec1.62.19.70.51.60.8-0.81.02.41.00.93.10.90.0
Delay discounting water rate 24 sec1.92.78.11.32.30.0-0.00.12.81.71.72.8-0.20.9
Delay discounting water rate 6 sec0.70.93.8-0.10.61.0-1.01.01.30.10.12.01.0-0.5
Locomotor activity3.96.18.6-2.9-2.92.1-2.11.9-2.8-2.9-2.9-1.52.1-2.7
Locomotor testing distance2.23.65.0-2.2-2.11.7-1.71.7-2.0-2.1-2.2-0.91.8-2.1
Locomotor testing rearing0.10.10.8-0.00.20.3-0.40.30.50.10.10.90.3-0.2
Light reinforcement 15.19.311.4-3.3-3.03.2-3.23.1-2.8-3.4-3.3-0.93.2-3.3
Light reinforcement 22.02.63.4-1.7-1.71.6-1.61.5-1.5-1.8-1.8-0.91.7-1.7
Reaction time number correct1.11.54.21.31.5-0.60.6-0.42.01.31.31.7-0.71.0
Reaction time mean minus median0.60.81.5-1.0-0.71.0-1.01.0-0.3-0.8-0.8-0.11.2-1.2
Reaction time mean minus median AUC0.30.41.8-0.5-0.8-0.20.2-0.1-0.9-0.5-0.5-1.3-0.0-0.5
Reaction time num false alarms0.20.31.50.40.5-0.10.1-0.11.20.40.41.1-0.20.0
Reaction time num false alarms AUC0.40.62.30.60.9-0.10.2-0.11.50.70.71.5-0.20.3
Reaction time trials correct on left1.11.54.21.31.5-0.60.6-0.42.01.31.31.7-0.71.0
Reaction time trials on left1.01.43.81.31.5-0.60.6-0.52.01.31.31.6-0.70.9
Reaction time mean0.10.21.0-0.4-0.5-0.20.2-0.2-0.5-0.3-0.2-1.00.0-0.3
Reaction time mean AUC0.10.21.1-0.3-0.5-0.30.3-0.3-0.5-0.3-0.2-1.1-0.1-0.3
Median of all reaction times0.20.31.00.1-0.1-0.70.7-0.7-0.30.10.2-1.0-0.50.3
Reaction time omissions0.30.40.7-0.8-0.70.5-0.50.4-0.8-0.7-0.7-0.50.4-0.6
Reaction time false alarm rate0.00.00.10.0-0.0-0.10.1-0.10.20.00.00.2-0.1-0.1
Reaction time premature initiation rate0.91.22.2-1.0-0.51.4-1.41.4-0.1-0.8-0.80.81.5-1.1
Reaction time premature initiations0.71.03.0-0.40.31.2-1.21.31.0-0.2-0.21.71.2-0.7
Std. dev. reaction times0.30.40.7-0.7-0.60.5-0.50.5-0.4-0.6-0.6-0.60.7-0.8
Reaction time trials completed1.01.43.81.31.5-0.60.6-0.52.01.31.31.6-0.70.9
Reaction time trials AUC1.11.64.61.31.6-0.50.5-0.42.21.31.31.9-0.60.9
Social response proportion0.70.81.6-0.9-1.00.7-0.70.7-1.3-1.0-1.0-1.00.8-0.6
Social responses6.88.711.6-3.3-3.12.9-2.82.8-2.8-3.3-3.4-1.42.8-3.3
Social time0.60.71.41.10.9-0.80.8-0.90.31.01.00.2-0.71.2
Conditioned locomotion2.12.54.21.81.9-1.00.9-0.92.11.81.81.7-0.91.6
Cocaine response after cond. corrected5.76.49.92.93.0-2.12.1-2.03.12.92.91.9-2.02.6
Cocaine response after cond. not corrected6.26.910.83.03.1-2.12.1-2.13.33.03.01.9-2.02.7
Cocaine response before conditioning0.50.60.9-0.8-0.90.6-0.70.6-0.7-1.0-0.9-0.70.7-0.9
Saline control response0.10.10.30.40.5-0.10.1-0.20.30.40.40.5-0.10.4
Condit. Reinf. active minus inactive responses1.72.23.7-1.4-0.81.9-1.91.9-0.2-1.3-1.31.01.9-1.6
Condit. Reinf. active-inactive response ratio0.50.62.70.20.80.6-0.60.70.90.40.41.60.60.1
Condit. Reinf. active responses1.92.63.9-1.8-1.41.9-1.81.8-0.7-1.7-1.70.21.8-2.0
Condit. Reinf. inactive responses1.31.62.7-1.5-1.41.1-1.11.1-0.8-1.5-1.5-0.71.1-1.6
Condit. Reinf. lever presses1.82.44.2-1.5-1.02.0-2.01.9-0.4-1.4-1.40.72.0-1.8
Condit. Reinf. lever reinforcers received1.31.92.8-1.4-1.01.7-1.71.7-0.2-1.3-1.30.51.7-1.7
Pavlov. Cond. lever latency0.81.11.91.21.1-1.11.1-1.00.51.21.20.4-1.11.4
Pavlov. Cond. magazine entry latency0.50.61.2-0.9-0.80.7-0.70.6-0.5-0.9-0.8-0.40.7-1.1
Pavlov. Cond. change in total contacts0.70.91.5-1.1-0.91.1-1.11.1-0.4-1.0-1.0-0.01.1-1.2
Pavlov. Cond. index score0.91.11.9-1.2-1.01.1-1.21.0-0.5-1.2-1.1-0.21.2-1.4
Pavlov. Cond. latency score0.91.11.9-1.2-1.11.0-1.10.9-0.6-1.2-1.2-0.51.1-1.4
Pavlov. Cond. lever contacts0.60.91.5-1.0-0.71.1-1.21.0-0.1-1.0-0.90.11.1-1.2
Pavlov. Cond. magazine entry number0.81.01.91.21.1-0.90.9-0.90.61.11.10.5-1.01.4
Pavlov. Cond. intertrial magazine entries0.50.61.20.91.0-0.40.4-0.41.10.90.90.9-0.40.8
Pavlov. Cond. lever-magazine prob. diff.0.91.22.0-1.2-1.11.1-1.11.0-0.6-1.3-1.2-0.41.2-1.4
Pavlov. Cond. response bias1.52.13.3-1.5-1.21.7-1.71.6-0.4-1.5-1.40.21.7-1.8
Conditioned reinforcement - actives2.02.02.8-1.6-1.31.5-1.61.3-1.1-1.5-1.7-0.21.3-1.7
Conditioned reinforcement - inactives0.70.71.30.91.1-0.70.6-0.71.11.00.90.7-0.70.9
Conditioned locomotion6.27.410.0-3.1-2.33.1-2.92.9-2.0-2.8-3.0-0.22.9-3.2
Intermittent access intake day 1-15 change5.35.37.5-2.6-1.92.7-2.62.5-1.4-2.4-2.40.22.6-2.7
Intermittent access intake escalation4.64.58.0-2.2-1.32.8-2.62.6-0.6-1.9-2.01.12.6-2.5
Intermittent access intake escalation 25.85.710.1-2.4-1.43.2-3.12.9-0.7-2.1-2.21.23.0-2.7
Intermitt. access day 1 inactive lever presses0.20.20.7-0.40.20.7-0.50.40.5-0.0-0.20.90.5-0.5
Intermitt. access day 15 inactive lever presses0.40.41.0-0.6-0.30.9-0.80.8-0.1-0.5-0.50.31.0-0.6
Intermitt. access escalation Index0.50.41.30.0-0.6-0.70.7-0.8-0.7-0.3-0.1-1.2-0.80.2
Intermittent access day 1 total infusions0.00.00.10.10.0-0.20.3-0.10.00.10.0-0.2-0.10.2
Intermittent access day 15 total infusions1.51.73.0-1.3-0.81.7-1.61.6-0.4-1.2-1.30.51.7-1.5
Intermittent access terminal intake (last 3 days)0.91.01.6-1.1-0.81.2-1.11.0-0.5-1.0-1.10.11.3-1.2
Intermittent access total infusions0.20.20.4-0.4-0.20.5-0.50.5-0.0-0.3-0.50.20.7-0.5
Intermittent access day 1 locomotion0.30.30.5-0.5-0.30.6-0.60.7-0.2-0.5-0.60.10.7-0.5
Intermittent access day 15 total locomotion2.72.94.2-1.9-1.32.1-1.91.9-1.1-1.7-1.80.12.0-1.9
Intermittent access total locomotion0.80.91.4-1.2-0.81.0-0.90.9-0.8-1.0-1.2-0.21.0-1.1
Intermittent access standard deviation2.12.33.9-1.7-0.92.0-1.81.7-0.5-1.3-1.50.51.9-1.8
Cocaine induced anxiety1.01.12.8-1.1-1.30.6-0.70.4-1.7-1.2-1.2-1.20.7-0.9
Post-drug Anxiety0.80.92.2-0.9-1.20.4-0.60.5-1.5-1.0-1.0-1.40.7-0.7
Baseline Anxiety0.20.20.60.10.30.4-0.50.60.70.10.10.80.6-0.2
Lifetime Intake0.10.10.2-0.3-0.10.3-0.30.3-0.0-0.2-0.40.10.4-0.3
Incentive Sensitization - Responses0.20.20.6-0.30.20.5-0.40.20.40.0-0.20.80.2-0.4
Incentive Sensitization - Breakpoint0.20.20.4-0.40.10.6-0.40.30.2-0.1-0.30.70.3-0.5
Progressive ratio test 1 active lever presses0.20.20.50.50.5-0.20.2-0.10.70.50.40.5-0.00.4
Progressive ratio test 1 breakpoint0.20.20.60.50.6-0.40.3-0.20.70.50.50.4-0.20.5
Progressive ratio test 1 inactive lever presses0.00.00.0-0.1-0.10.1-0.00.1-0.1-0.1-0.2-0.20.1-0.1
Progressive ratio test 2 active lever presses0.20.20.4-0.30.20.5-0.40.40.4-0.0-0.20.70.5-0.4
Progressive ratio test 2 breakpoint0.20.20.3-0.5-0.20.5-0.40.4-0.0-0.3-0.50.20.5-0.6
Progressive ratio test 2 inactive lever presses0.00.10.2-0.3-0.20.1-0.00.0-0.3-0.2-0.4-0.20.2-0.2
Total sessions with >9 infusions0.10.10.4-0.2-0.4-0.20.1-0.3-0.4-0.2-0.4-0.6-0.3-0.1
Short access day 1 total inactive lever presses0.00.00.1-0.1-0.10.1-0.20.2-0.2-0.2-0.2-0.00.20.0
Short access day 10 total inactive lever presses0.10.10.3-0.10.40.4-0.20.20.20.20.10.60.2-0.1
Short access day 1 total infusions0.40.40.9-0.6-0.80.2-0.30.1-0.9-0.7-0.8-0.90.2-0.4
Short access day 10 total infusions0.00.00.2-0.00.10.2-0.10.30.40.1-0.10.30.3-0.0
Short access total infusions0.00.00.1-0.1-0.1-0.10.0-0.1-0.2-0.1-0.2-0.2-0.1-0.0
Short access day 1 locomotion1.31.42.2-1.3-1.40.9-0.90.8-1.2-1.4-1.5-1.00.9-1.3
Short access day 10 total locomotion3.23.55.0-2.1-1.52.2-2.22.1-1.0-1.9-2.00.32.0-2.2
Short access total locomotion0.90.91.5-1.2-1.00.9-1.00.8-0.8-1.1-1.2-0.40.8-1.1
Compulsive drug intake0.90.92.00.80.5-1.31.2-1.30.10.80.7-0.5-1.41.0
One hour access (0.3 mA shock)0.10.20.30.40.4-0.50.6-0.30.40.50.3-0.0-0.30.4
One hour access (shock baseline)0.10.10.3-0.10.20.3-0.30.50.60.0-0.10.50.6-0.2
Number of responses in last shaping day0.20.20.4-0.5-0.40.4-0.30.2-0.2-0.4-0.7-0.20.3-0.5
Context. condit. distance diff. score0.30.30.50.60.6-0.60.6-0.60.70.60.60.3-0.60.5
Locomotion velocity, session 11.11.23.0-1.1-1.40.5-0.40.5-1.6-1.2-1.2-1.70.5-0.9
Locomotion distance, session 11.01.35.0-0.8-1.3-0.10.2-0.1-2.1-1.0-0.9-2.2-0.2-0.3
Locomotion velocity, session 24.45.29.2-2.4-2.71.6-1.51.7-3.0-2.5-2.5-2.61.7-2.0
Locomotion distance, session 22.53.69.2-1.9-2.31.0-0.91.0-3.0-2.0-2.0-2.61.0-1.4
Locomotion velocity, session 35.05.88.2-2.6-2.12.7-2.72.9-1.5-2.5-2.5-0.12.8-2.8
Locomotion distance, session 30.00.00.10.10.20.0-0.00.00.40.10.10.20.0-0.0
Stereotopy head waving bouts, day 34.35.16.3-2.5-2.32.3-2.22.3-2.3-2.5-2.5-0.82.4-2.4
Stereotopy head waving duration, day 34.96.07.2-2.7-2.42.5-2.52.6-2.1-2.7-2.6-0.62.7-2.6
Locomotion velocity, session 70.80.91.6-1.1-1.10.8-0.80.7-0.4-1.1-1.1-0.60.9-1.3
Locomotion distance, session 70.30.31.40.50.8-0.10.1-0.21.20.60.60.80.00.3
Stereotopy head waving bouts, day 70.40.41.7-0.5-0.9-0.30.3-0.2-1.1-0.5-0.5-1.3-0.3-0.3
Stereotopy head waving duration, day 70.70.92.3-1.0-1.30.1-0.10.2-1.5-1.0-1.0-1.50.1-0.7
Locomotion velocity, session 81.51.84.9-1.3-1.80.3-0.30.4-2.1-1.4-1.4-2.20.3-0.9
Locomotion distance, session 80.20.31.0-0.5-0.60.2-0.20.2-1.0-0.5-0.5-0.80.2-0.3
Degree of sensitization distance0.30.30.50.60.5-0.60.6-0.70.40.50.5-0.0-0.60.6
Degree of sensitization stereotypy1.31.43.11.00.4-1.61.6-1.60.10.90.9-1.0-1.81.1
Condit. Reinf. active minus inactive responses3.43.85.0-2.1-1.82.2-2.12.2-1.5-2.0-2.1-0.42.1-2.2
Condit. Reinf. active-inactive response ratio1.51.72.9-1.3-0.81.7-1.61.7-0.3-1.1-1.20.41.6-1.5
Condit. Reinf. active responses3.54.25.4-2.3-2.21.9-1.92.0-2.3-2.3-2.3-1.21.9-2.1
Condit. Reinf. inactive responses1.31.54.2-1.3-1.60.7-0.60.7-2.0-1.4-1.4-1.40.7-0.9
Incentive salience index mean2.12.63.4-1.8-1.81.4-1.41.5-1.8-1.8-1.8-1.01.4-1.7
Condit. Reinf. lever presses0.71.03.7-0.6-1.2-0.30.4-0.3-1.9-0.7-0.8-1.8-0.4-0.3
Time in familiar zone, hab. session 11.71.62.8-1.3-0.91.5-1.61.7-0.3-1.2-1.20.61.6-1.5
Time in novel zone, hab. session 10.90.81.70.50.0-1.21.2-1.3-0.30.40.4-1.3-1.30.7
Total zone transitions, hab. session 11.42.04.9-1.5-1.80.8-0.70.8-2.2-1.6-1.6-1.90.7-1.1
Total locomotion distance, hab. session 12.33.37.9-1.8-2.40.6-0.60.7-2.8-2.0-2.0-2.80.6-1.4
Locomotion velocity, hab. session 12.33.37.7-1.9-2.31.0-1.01.0-2.8-2.0-2.0-2.40.9-1.5
Time in familiar zone, hab. session 24.64.87.9-2.1-1.42.8-2.82.8-0.6-1.9-2.00.92.8-2.4
Time in novel zone, hab. session 23.33.35.81.71.0-2.42.4-2.40.41.51.6-1.0-2.41.9
Total zone transitions, hab. session 20.91.25.8-0.1-0.8-0.80.8-0.7-1.9-0.4-0.3-2.4-0.70.5
Total locomotion distance, hab. session 21.41.84.9-1.3-1.60.7-0.70.8-2.2-1.5-1.4-1.90.8-0.9
Locomotion velocity, hab. session 21.72.26.6-1.4-1.80.6-0.60.7-2.6-1.6-1.5-2.30.7-0.9
Novel to familiar place preference ratio3.03.26.51.50.7-2.32.3-2.40.11.31.4-1.4-2.61.8
Novelty place preference1.92.04.21.10.4-1.81.9-1.9-0.10.91.0-1.4-2.11.4
Time in novel zone, NPP test2.12.24.61.30.6-1.92.0-2.00.11.11.1-1.2-2.11.5
Total zone transitions, NPP test0.30.52.4-0.2-0.5-0.30.3-0.2-1.4-0.2-0.3-1.5-0.20.3
Total locomotion distance, NPP test0.50.63.5-0.2-0.7-0.50.5-0.4-1.4-0.3-0.3-1.9-0.40.2
Locomotion velocity, NPP test0.50.73.5-0.5-0.9-0.20.2-0.1-1.6-0.6-0.6-1.9-0.1-0.0
Pavlov. Cond. lever latency0.30.41.40.30.70.4-0.40.31.10.40.41.20.40.1
Pavlov. Cond. magazine entry latency2.22.84.3-1.8-1.32.0-2.02.1-1.1-1.7-1.70.22.0-1.8
Pavlov. Cond. change in total contacts0.00.00.1-0.3-0.30.2-0.20.2-0.4-0.3-0.3-0.00.1-0.2
Pavlov. Cond. index score0.50.61.3-0.9-1.00.5-0.50.6-1.1-0.9-0.9-0.70.4-0.7
Pavlov. Cond. latency score0.70.82.1-1.0-1.20.4-0.40.5-1.4-1.0-1.1-1.10.3-0.8
Pavlov. Cond. lever contacts0.50.62.0-0.6-1.1-0.20.2-0.1-1.4-0.7-0.7-1.4-0.3-0.3
Pavlov. Cond. magazine entry number0.50.61.00.90.7-0.90.9-1.00.60.80.8-0.0-0.90.8
Pavlov. Cond. intertrial magazine entries0.20.31.10.00.40.6-0.60.60.60.10.11.10.6-0.2
Pavlov. Cond. lever-magazine prob. diff.0.81.01.5-1.1-1.20.8-0.80.9-1.2-1.1-1.1-0.70.7-1.0
Pavlov. Cond. response bias0.91.01.5-1.1-0.91.1-1.11.2-0.9-1.1-1.1-0.21.0-1.1
Bone: apparent density0.91.65.6-0.9-1.6-0.70.7-0.6-2.0-1.1-1.1-2.4-0.6-0.5
Bone surface2.34.112.4-1.8-2.8-0.30.4-0.2-3.2-2.1-2.1-3.5-0.3-1.4
Bone volume2.54.212.4-1.8-2.9-0.30.4-0.3-3.2-2.1-2.1-3.5-0.3-1.4
Bone: connectivity density0.50.93.2-0.2-0.9-1.01.0-0.8-1.2-0.4-0.4-1.8-0.90.1
Bone: cortical apparent density0.70.91.21.00.9-1.01.0-1.00.71.01.00.3-1.11.0
Bone: cortical area0.40.61.50.3-0.3-1.11.1-1.1-0.40.10.1-1.2-1.10.3
Bone: cortical porosity0.80.91.6-1.0-1.20.6-0.60.6-1.3-1.1-1.1-0.90.5-0.9
Bone: cortical porosity0.50.62.1-0.6-1.0-0.10.1-0.1-1.3-0.7-0.7-1.5-0.2-0.3
Bone: cortical thickness0.71.22.31.00.6-1.51.4-1.50.30.90.9-0.6-1.41.1
Bone: cortical thickness0.20.20.90.20.60.3-0.30.21.00.40.40.90.3-0.0
Bone: cortical tissue density0.50.60.80.80.7-0.80.8-0.80.60.80.80.3-0.90.9
Bone: elastic displacement0.30.30.4-0.6-0.70.5-0.50.4-0.6-0.7-0.7-0.30.5-0.6
Bone: elastic work0.10.20.40.2-0.2-0.60.6-0.6-0.10.00.0-0.6-0.50.2
Bone: endosteal estimation0.10.30.70.30.0-0.80.8-0.70.00.30.3-0.5-0.70.3
Bone: endosteal perimeter0.51.01.8-1.1-1.40.4-0.40.5-1.2-1.2-1.2-1.10.5-1.1
Bone: final force0.81.22.60.90.3-1.61.6-1.50.20.80.8-1.0-1.50.9
Bone: final moment0.61.02.10.70.2-1.41.4-1.40.10.60.6-0.9-1.40.8
Bone: marrow area0.10.30.70.30.1-0.80.9-0.70.00.30.3-0.5-0.70.3
Bone: maximum diameter1.22.13.7-1.7-1.90.8-0.80.8-1.8-1.7-1.7-1.60.8-1.6
Bone: maximum force0.71.32.61.00.5-1.61.6-1.50.50.90.9-0.7-1.51.0
Bone: maximum moment0.61.02.10.90.4-1.51.4-1.40.40.80.8-0.8-1.30.8
Bone: minimum diameter0.10.20.6-0.4-0.7-0.30.3-0.2-0.6-0.4-0.4-0.8-0.2-0.4
Bone: periosteal estimation0.30.61.70.1-0.4-1.11.1-1.0-0.50.00.0-1.3-1.00.2
Bone: periosteal perimeter0.50.82.0-0.9-1.3-0.00.00.1-1.2-1.0-1.0-1.40.0-0.8
Bone: post-yield work0.50.60.80.90.8-0.80.8-0.70.90.90.90.2-0.80.7
Bone: stiffness2.13.35.51.81.3-2.32.3-2.31.01.71.7-0.4-2.21.8
Bone: tissue strength1.31.21.81.10.9-1.41.3-1.40.51.11.1-0.2-1.31.2
Bone: trabecular number1.32.03.7-1.5-1.90.6-0.60.6-1.9-1.6-1.6-1.90.6-1.3
Bone: trabecular spacing2.02.67.41.52.2-0.10.1-0.12.61.71.72.7-0.01.1
Bone: trabecular thickness2.53.010.4-1.3-2.3-0.70.7-0.7-2.8-1.6-1.6-3.2-0.7-0.8
Bone: trabecular tissue density1.92.63.91.91.9-1.41.4-1.31.51.91.91.2-1.32.0
Breakpoint value in progressive ratio session4.04.57.3-2.2-1.52.7-2.62.5-1.0-2.0-2.10.72.5-2.4
Distance traveled before self-admin0.30.30.80.30.2-0.70.7-0.9-0.20.50.3-0.6-0.90.5
Distance traveled after self-admin0.70.81.3-1.2-0.90.9-0.80.6-1.0-0.9-0.9-0.50.7-1.0
Delta time in closed arm before/after self-admin2.42.36.11.42.1-0.40.3-0.42.41.61.62.5-0.41.1
Delta time in open arm before/after self-admin0.80.81.30.90.6-1.11.1-1.10.30.80.9-0.6-1.01.0
Diff in mean of infusions in LGA sessions1.41.62.3-1.3-1.11.4-1.41.5-0.9-1.3-1.1-0.01.4-1.4
Extinction: sum of active levers before priming0.80.91.8-0.7-0.01.3-1.31.10.1-0.4-0.71.21.1-0.9
Active lever presses in extinction session 62.62.53.4-1.8-1.61.8-1.61.4-1.4-1.6-1.7-0.41.5-1.8
Delta distance traveled before/after self-admin1.51.62.1-1.3-1.21.4-1.41.3-0.9-1.4-1.2-0.21.4-1.4
Delta ambulatory time before/after self-admin1.61.82.4-1.5-1.41.4-1.41.4-1.1-1.5-1.3-0.51.4-1.5
Time in closed arm before self-admin0.80.92.30.5-0.2-1.21.2-1.1-0.70.30.3-1.5-1.20.8
Time in closed arm after self-admin0.00.00.10.10.10.1-0.20.20.2-0.00.10.30.10.0
Time in open arm before self-admin0.70.71.2-1.0-0.61.0-1.00.9-0.3-0.8-0.80.60.9-1.1
Time in open arm after self-admin0.60.60.80.80.8-0.80.9-0.80.70.90.90.2-0.80.8
Sum of active levers in priming session hrs 5-60.00.00.00.00.00.10.1-0.1-0.10.10.0-0.1-0.10.1
Time to tail flick, vehicle, before self-admin0.90.91.9-1.0-1.20.4-0.30.5-1.4-1.0-1.1-1.40.4-0.8
Time to tail flick, vehicle, after self-admin0.50.52.20.30.60.5-0.60.71.00.20.31.50.7-0.0
Time to tail flick, test, before self-admin0.60.61.6-0.6-1.10.0-0.20.2-1.2-0.8-0.9-1.30.2-0.5
Time to tail flick, test, after self-admin0.30.30.6-0.6-0.70.2-0.30.7-0.7-0.6-0.7-0.80.5-0.5
Delta time to tail flick, vehicle, before/after SA1.41.44.21.21.5-0.30.2-0.21.91.21.22.0-0.20.9
Delta time to tail flick, test, before/after SA0.20.20.6-0.10.30.4-0.50.60.60.10.10.70.5-0.2
Ambulatory time before self-admin0.30.30.70.30.3-0.60.7-0.8-0.10.50.4-0.4-0.70.5
Ambulatory time after self-admin0.40.40.8-0.9-0.70.7-0.60.4-0.8-0.6-0.7-0.50.4-0.7
Total heroin consumption1.61.92.7-1.5-1.31.6-1.41.5-1.1-1.4-1.6-0.11.5-1.6
Area under the delay curve1.61.72.81.30.9-1.71.6-1.50.81.21.3-0.2-1.61.3
Delay disc. indifference point, 0s delay5.25.710.12.21.1-3.23.2-3.10.01.91.9-1.9-3.02.7
Delay disc. indifference point, 16s delay0.10.10.20.30.1-0.40.4-0.40.20.20.4-0.0-0.50.2
Delay disc. indifference point, 2s delay4.24.77.72.21.5-2.82.8-2.60.92.12.0-0.8-2.72.4
Delay disc. indifference point, 24s delay0.60.61.00.80.7-0.70.7-0.90.80.71.00.6-0.90.7
Delay disc. indifference point, 4s delay0.70.71.70.70.1-1.31.2-1.00.20.50.7-0.6-1.20.7
Delay disc. indifference point, 8s delay1.11.11.61.21.1-1.01.0-0.91.21.21.30.5-0.81.1
Delay discount exponential model param1.51.52.5-1.3-0.91.6-1.51.4-0.9-1.2-1.30.11.5-1.3
Delay discount hyperbolic model param2.12.23.6-1.5-1.01.9-1.81.7-1.0-1.4-1.50.21.8-1.5
Fecal boli incidents, locomotor time 12.12.23.41.71.8-1.21.2-1.71.21.71.70.6-1.41.8
Change in fecal boli incidents, locomotor task0.70.71.5-0.9-1.20.3-0.30.1-0.8-0.9-1.1-0.90.3-1.0
Time >=10cm from walls, locomotor time 10.50.51.40.2-0.3-0.70.7-1.2-0.7-0.00.1-1.1-0.80.5
Bouts of movement, locomotor time 10.10.10.2-0.4-0.20.5-0.50.4-0.0-0.2-0.30.00.4-0.4
Total resting periods, locomotor time 10.20.20.4-0.5-0.40.5-0.50.4-0.2-0.4-0.5-0.20.4-0.6
Rest time, locomotor task time 10.20.20.4-0.6-0.50.4-0.30.4-0.6-0.5-0.6-0.40.2-0.5
Distance moved, locomotor task time 10.40.41.20.2-0.3-0.90.8-1.1-0.5-0.10.2-1.0-0.80.4
Vertical activity count, locomotor time 10.10.10.50.30.3-0.20.2-0.30.70.30.20.5-0.10.0
Time >=10cm from walls, locomotor time 21.11.21.61.21.2-1.01.0-1.21.11.21.30.6-1.01.2
Bouts of movement, locomotor time 20.80.82.0-0.9-1.20.3-0.30.7-1.4-1.0-1.0-1.40.4-0.7
Total resting periods, locomotor time 20.80.82.1-0.9-1.20.3-0.30.7-1.4-1.0-0.9-1.40.4-0.7
Rest time, locomotor task time 20.70.81.3-1.0-1.20.6-0.70.7-1.1-1.1-0.9-0.80.7-0.9
Distance moved, locomotor task time 20.91.01.51.11.2-0.80.8-0.81.11.21.10.8-0.81.1
Vertical activity count, locomotor time 21.21.32.51.21.5-0.60.7-0.71.61.41.21.3-0.61.1
Weight adjusted by age0.70.82.21.01.2-0.30.3-0.41.50.90.91.4-0.30.7
Seeking ratio, delayed vs. immediate footshock4.34.96.6-2.5-2.32.2-2.12.1-2.0-2.5-2.5-0.82.1-2.6
Locomotion in novel chamber0.20.30.8-0.30.20.8-0.70.50.0-0.1-0.20.90.6-0.3
Locomotion in novel chamber post-restriction0.70.81.3-0.9-0.81.0-1.01.2-0.2-1.0-1.00.51.0-1.1
Progressive ratio0.50.51.20.91.1-0.40.4-0.30.70.90.90.5-0.30.9
Food seeking constrained by brief footshock0.10.10.3-0.2-0.10.3-0.20.4-0.6-0.2-0.3-0.30.3-0.1
Seeking ratio, punishment vs. effort0.30.40.7-0.7-0.80.3-0.40.4-0.8-0.7-0.8-0.60.3-0.6
Run reversals in cocaine runway, females0.40.40.7-0.8-0.80.5-0.50.6-0.7-0.7-0.8-0.40.5-0.8
Run reversals in cocaine runway, males1.31.31.9-1.2-1.31.0-1.01.2-1.1-1.3-1.4-0.61.0-1.2
Latency to leave start box in cocaine runway1.61.73.7-1.6-1.70.7-0.60.5-1.9-1.5-1.6-1.20.7-1.4
Latency to leave start box in cocaine runway, F1.01.14.0-0.8-1.2-0.40.5-0.7-1.8-0.7-1.0-2.0-0.4-0.4
Latency to leave start box in cocaine runway, M2.22.13.7-1.3-0.61.9-1.91.9-0.1-1.1-1.01.41.9-1.6
Cd content in liver0.10.20.30.30.2-0.50.5-0.50.00.30.3-0.4-0.50.4
Co content in liver0.40.50.9-0.7-0.40.9-0.90.9-0.3-0.6-0.60.20.9-0.8
Cu content in liver0.40.42.4-0.2-0.5-0.50.6-0.6-0.9-0.2-0.2-1.6-0.50.0
Fe content in liver0.10.10.20.10.30.2-0.30.30.40.20.10.40.30.0
K content in liver0.40.41.5-0.4-0.7-0.30.3-0.3-1.2-0.4-0.4-1.2-0.3-0.1
Mg content in liver0.40.41.8-0.5-0.8-0.30.4-0.4-1.2-0.4-0.5-1.4-0.3-0.2
Mn content in liver2.73.17.6-1.8-2.40.5-0.40.5-2.6-1.9-2.0-2.80.5-1.5
Na content in liver0.80.91.60.60.2-1.21.3-1.2-0.40.60.5-1.1-1.20.9
Rb content in liver0.50.62.20.1-0.4-0.90.9-0.9-0.8-0.00.0-1.5-1.00.4
Se content in liver0.20.20.2-0.5-0.50.4-0.40.4-0.5-0.4-0.5-0.40.3-0.4
Sr content in liver0.30.31.40.30.70.3-0.30.30.90.40.41.20.20.1
Zn content in liver1.51.73.8-0.80.21.8-1.81.80.7-0.4-0.51.91.6-1.1