Hub : Genes

Timeless

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000031916 0.28 0.13 0.0e+00 0.22 0.24 0.22 0.24 1.2e-24 7.0e-26 2.5e-24 7.3e-26
2 Adipose intron excision ratio chr7:668828:670225 0.03 0.02 1.6e-03 0.01 0.01 0.01 0.01 3.4e-02 1.3e-02 1.8e-02 2.9e-02
3 Adipose mRNA stability ENSRNOG00000031916 0.17 0.1 0.0e+00 0.14 0.13 0.13 0.14 1.2e-15 1.3e-14 1.1e-14 3.5e-15
4 BLA gene expression ENSRNOG00000031916 0.05 0.04 5.7e-03 0.03 0.03 0.01 0.03 1.4e-02 7.8e-03 4.8e-02 1.2e-02
5 BLA isoform ratio ENSRNOT00000083899 0.1 0.07 1.1e-04 0.07 0.07 0.07 0.07 8.5e-05 1.3e-04 1.5e-04 1.7e-04
6 Brain gene expression ENSRNOG00000031916 0.14 0.12 8.3e-08 0.06 0.07 0.08 0.07 1.5e-06 2.6e-07 1.5e-07 2.9e-07
7 Brain isoform ratio ENSRNOT00000083899 0.06 0.05 1.7e-03 0.04 0.02 0.03 0.04 9.8e-05 5.3e-03 1.4e-03 2.4e-04
8 Liver gene expression ENSRNOG00000031916 0.24 0.12 0.0e+00 0.22 0.23 0.22 0.22 1.6e-24 8.1e-25 9.4e-24 2.1e-24
9 Liver mRNA stability ENSRNOG00000031916 0.11 0.07 8.4e-12 0.1 0.08 0.08 0.09 7.4e-11 3.3e-09 6.2e-09 4.2e-10
10 PL gene expression ENSRNOG00000031916 0.17 0.11 4.0e-11 0.14 0.14 0.12 0.14 3.9e-11 1.5e-10 1.2e-09 9.5e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail8.326.932.45.3-5.35.05.4-5.74.3-5.35.15.15.2
BMI without tail1.42.83.71.9-1.91.91.8-1.51.1-1.31.91.81.5
Body weight1.14.96.02.4-2.42.22.4-2.41.5-2.02.31.92.1
Epididymis fat weight0.10.10.4-0.30.3-0.2-0.40.00.40.5-0.2-0.1-0.6
Glucose1.72.63.31.8-1.81.71.8-1.60.7-1.51.71.61.6
Heart weight0.00.10.30.3-0.20.60.10.2-0.10.20.30.10.2
Left kidney weight0.10.20.90.0-0.1-0.20.4-0.50.7-0.1-0.2-0.70.9
Right kidney weight0.30.81.9-0.90.9-1.0-0.80.7-0.90.9-1.0-1.4-0.5
Tail length5.315.921.7-3.83.8-3.6-4.14.6-3.54.7-3.6-3.7-4.4
Length with tail2.07.28.8-2.72.7-2.7-2.72.8-2.13.0-2.6-2.9-2.7
Length without tail0.10.30.70.2-0.2-0.00.5-0.80.6-0.70.1-0.00.8
Liver weight, left1.72.73.71.8-1.81.91.7-1.60.9-1.41.81.91.4
Liver weight, right0.81.41.91.3-1.31.31.3-0.81.1-0.81.21.01.4
Parametrial fat weight0.00.00.1-0.10.10.1-0.2-0.10.30.3-0.10.1-0.3
Retroperitoneal fat weight2.27.39.33.0-3.12.93.0-2.61.7-2.13.02.62.7
Intraocular pressure0.40.51.2-0.50.5-0.3-0.80.8-1.10.8-0.3-0.2-1.1
Extensor digitorum longus weight5.120.326.05.1-5.15.04.8-4.12.4-4.15.14.44.3
Soleus weight5.616.420.14.5-4.54.14.5-3.92.2-4.14.33.84.3
Tibialis anterior weight1.03.64.72.1-2.21.82.2-1.91.3-1.52.11.72.0
Tibia length1.13.24.7-1.71.7-1.6-1.92.2-1.22.1-1.6-1.6-2.0
Number of licking bursts3.84.56.62.2-2.22.32.0-2.02.2-1.72.32.61.6
Food consumed during 24 hour testing period0.50.60.90.8-0.80.60.8-0.90.5-0.80.80.80.7
Times rat made contact with spout1.11.31.71.2-1.31.21.1-1.30.4-1.11.31.20.9
Mean time between licks in bursts0.60.81.3-1.01.0-0.7-1.10.9-0.81.1-0.8-0.4-1.2
Mean num. licks in bursts1.11.32.8-1.11.1-1.2-1.00.9-1.70.8-1.1-1.4-0.8
Std. dev. time between licks in bursts0.40.51.1-0.90.9-1.1-0.60.3-0.10.4-1.0-0.7-0.5
Water consumed over 24 hours0.91.12.20.8-0.80.51.1-1.51.1-1.40.60.51.3
Indifference point 0 sec4.06.49.42.5-2.52.12.7-3.11.4-3.02.42.42.8
Indifference point AUC0.60.71.0-0.90.9-0.7-0.91.0-0.11.0-0.8-0.7-0.9
Indifference point function ln k0.20.30.40.5-0.60.40.6-0.5-0.6-0.60.50.40.5
Indifference point function log k0.20.30.40.5-0.60.40.6-0.5-0.6-0.60.50.40.5
Delay discounting total patch changes 0 sec3.86.29.02.5-2.52.12.6-3.01.4-2.92.42.52.6
Delay discounting total patch changes 12 sec2.02.74.01.7-1.71.71.6-1.51.3-1.51.82.01.3
Delay discounting total patch changes 18 sec0.00.10.10.2-0.20.20.2-0.30.3-0.30.20.30.3
Delay discounting total patch changes 24 sec0.50.60.70.7-0.70.60.8-0.80.8-0.80.70.80.9
Delay discounting total patch changes 6 sec2.03.14.11.8-1.81.61.9-2.01.0-1.91.71.81.8
Delay discounting time to switch 0 sec0.20.31.00.4-0.40.30.6-0.71.0-0.40.30.10.7
Delay discounting water rate 0 sec0.60.91.41.1-1.11.10.9-0.7-0.2-0.91.21.20.6
Delay discounting water rate 12 sec1.01.42.81.3-1.31.51.1-0.9-0.0-1.01.41.70.9
Delay discounting water rate 18 sec0.40.52.10.4-0.40.7-0.10.7-1.50.60.70.7-0.8
Delay discounting water rate 24 sec1.62.34.61.8-1.82.11.2-0.7-0.2-0.72.12.10.4
Delay discounting water rate 6 sec0.50.82.9-0.30.4-0.1-0.71.2-1.71.2-0.1-0.2-1.1
Locomotor activity4.46.99.8-2.62.6-3.0-2.52.2-2.42.6-2.7-3.1-2.4
Locomotor testing distance1.62.74.1-1.61.6-1.9-1.51.2-1.81.5-1.7-2.0-1.5
Locomotor testing rearing0.00.10.30.0-0.0-0.0-0.10.2-0.50.40.1-0.2-0.4
Light reinforcement 13.56.47.2-2.72.7-2.7-2.62.2-2.32.5-2.6-2.5-2.5
Light reinforcement 20.81.11.4-1.21.1-1.2-1.10.9-0.70.9-1.1-0.9-1.2
Reaction time number correct1.11.63.71.4-1.41.41.2-1.10.5-1.11.51.90.8
Reaction time mean minus median2.12.74.5-1.61.6-1.5-1.61.7-1.31.8-1.6-2.1-1.5
Reaction time mean minus median AUC2.12.65.2-1.81.8-2.0-1.51.2-0.51.3-2.0-2.3-1.1
Reaction time num false alarms0.50.61.01.0-1.00.80.9-0.40.4-0.61.00.80.7
Reaction time num false alarms AUC0.50.81.41.1-1.11.01.0-0.40.3-0.51.20.90.6
Reaction time trials correct on left1.11.63.71.4-1.41.41.2-1.10.5-1.11.51.90.8
Reaction time trials on left1.11.63.51.3-1.31.31.2-1.10.6-1.11.41.90.8
Reaction time mean1.41.94.0-1.61.6-1.4-1.41.0-0.51.1-1.7-2.0-0.9
Reaction time mean AUC0.70.92.4-1.11.1-0.9-0.90.5-0.20.6-1.2-1.5-0.4
Median of all reaction times0.60.92.1-1.11.1-0.9-0.90.5-0.20.6-1.2-1.4-0.5
Reaction time omissions0.00.00.2-0.10.10.00.0-0.40.0-0.1-0.1-0.20.2
Reaction time false alarm rate0.00.10.10.3-0.30.20.40.00.2-0.10.3-0.20.3
Reaction time premature initiation rate1.62.13.7-1.21.2-0.9-1.51.8-1.61.9-1.0-1.3-1.7
Reaction time premature initiations0.50.81.8-0.40.4-0.1-0.81.2-1.31.3-0.2-0.2-1.3
Std. dev. reaction times1.11.53.2-1.31.3-1.2-1.21.0-0.61.1-1.4-1.8-0.9
Reaction time trials completed1.11.63.51.3-1.31.31.2-1.10.6-1.11.41.90.8
Reaction time trials AUC1.31.84.11.5-1.51.51.2-1.20.5-1.11.62.00.8
Social response proportion1.01.11.8-1.21.2-1.1-1.11.0-0.40.9-1.2-1.3-0.8
Social responses9.412.215.6-3.83.8-3.7-3.63.3-2.03.4-3.8-3.9-3.2
Social time0.81.01.61.3-1.31.31.2-0.60.2-0.61.30.91.0
Conditioned locomotion1.01.22.31.3-1.31.51.0-0.70.3-0.71.51.40.6
Cocaine response after cond. corrected2.42.75.31.9-1.82.31.5-1.00.6-1.12.01.91.4
Cocaine response after cond. not corrected2.52.85.61.9-1.92.41.6-1.10.4-1.02.02.01.4
Cocaine response before conditioning0.50.60.9-0.80.8-1.0-0.80.6-0.60.7-0.9-0.9-0.7
Saline control response0.30.40.60.8-0.80.80.7-0.30.4-0.40.80.40.5
Condit. Reinf. active minus inactive responses1.72.13.0-1.41.4-1.0-1.61.6-1.71.7-1.2-1.1-1.7
Condit. Reinf. active-inactive response ratio0.60.62.0-0.40.40.1-0.81.1-1.41.1-0.2-0.1-1.0
Condit. Reinf. active responses1.11.61.9-1.31.3-1.2-1.41.1-1.41.2-1.2-1.0-1.3
Condit. Reinf. inactive responses0.30.30.8-0.70.7-0.9-0.60.1-0.20.2-0.8-0.6-0.4
Condit. Reinf. lever presses2.33.24.8-1.81.8-1.6-2.01.9-1.52.0-1.6-1.5-2.2
Condit. Reinf. lever reinforcers received0.81.11.5-1.11.1-0.9-1.21.0-1.21.1-1.0-0.8-1.2
Pavlov. Cond. lever latency1.72.32.81.6-1.51.71.6-1.50.8-1.61.51.71.6
Pavlov. Cond. magazine entry latency2.42.83.2-1.81.8-1.8-1.81.5-0.61.7-1.7-1.8-1.7
Pavlov. Cond. change in total contacts0.70.91.3-1.01.0-1.1-1.01.0-0.51.1-0.9-0.9-1.1
Pavlov. Cond. index score2.02.63.1-1.71.7-1.7-1.71.5-0.81.7-1.6-1.7-1.8
Pavlov. Cond. latency score2.22.83.6-1.81.8-1.9-1.81.5-0.81.7-1.7-1.8-1.7
Pavlov. Cond. lever contacts1.31.82.4-1.31.3-1.4-1.41.4-0.81.5-1.2-1.3-1.6
Pavlov. Cond. magazine entry number2.12.53.11.7-1.71.81.7-1.40.7-1.61.71.71.6
Pavlov. Cond. intertrial magazine entries0.70.91.51.2-1.21.21.0-0.5-0.1-0.71.20.90.7
Pavlov. Cond. lever-magazine prob. diff.2.12.73.3-1.71.7-1.8-1.81.5-0.91.7-1.7-1.7-1.7
Pavlov. Cond. response bias2.12.83.7-1.71.7-1.6-1.81.7-1.01.9-1.6-1.6-1.9
Conditioned reinforcement - actives0.10.10.2-0.10.1-0.30.0-0.20.2-0.5-0.2-0.10.4
Conditioned reinforcement - inactives1.41.52.41.5-1.41.61.2-0.90.6-0.81.51.51.0
Conditioned locomotion1.92.32.9-1.71.7-1.7-1.61.2-1.31.2-1.7-1.2-1.5
Intermittent access intake day 1-15 change0.30.31.5-0.30.3-0.3-0.40.5-1.20.3-0.30.0-0.5
Intermittent access intake escalation0.40.42.10.1-0.10.3-0.20.8-1.50.50.30.5-0.6
Intermittent access intake escalation 20.90.94.3-0.40.5-0.1-0.71.1-2.11.0-0.3-0.1-1.0
Intermitt. access day 1 inactive lever presses0.20.20.80.2-0.20.4-0.10.5-0.40.90.40.3-0.5
Intermitt. access day 15 inactive lever presses0.80.92.7-0.70.7-0.6-0.91.1-1.61.0-0.5-0.3-1.2
Intermitt. access escalation Index0.30.20.9-0.40.4-0.7-0.1-0.4-0.0-0.2-0.6-1.00.3
Intermittent access day 1 total infusions0.60.72.80.6-0.60.50.7-0.91.7-0.70.50.50.8
Intermittent access day 15 total infusions0.30.30.70.5-0.60.50.5-0.50.4-0.60.60.80.4
Intermittent access terminal intake (last 3 days)0.30.30.70.4-0.40.30.5-0.70.6-0.80.30.50.7
Intermittent access total infusions0.60.71.20.7-0.80.70.8-0.81.1-0.90.70.90.8
Intermittent access day 1 locomotion0.10.11.00.1-0.10.10.00.11.00.20.10.0-0.0
Intermittent access day 15 total locomotion0.30.30.6-0.50.5-0.3-0.60.8-0.40.8-0.4-0.3-0.6
Intermittent access total locomotion0.20.30.3-0.50.5-0.5-0.50.60.50.5-0.5-0.4-0.4
Intermittent access standard deviation0.10.10.6-0.10.2-0.0-0.30.6-0.80.4-0.10.2-0.4
Cocaine induced anxiety1.71.93.3-1.61.6-1.8-1.40.9-0.90.9-1.7-1.6-1.1
Post-drug Anxiety0.50.61.4-0.90.9-1.2-0.50.10.1-0.0-1.1-1.1-0.1
Baseline Anxiety0.00.00.20.2-0.20.40.10.2-0.00.10.20.10.0
Lifetime Intake1.31.52.11.1-1.10.91.2-1.41.4-1.41.01.11.4
Incentive Sensitization - Responses0.10.10.7-0.30.3-0.2-0.30.4-0.80.3-0.3-0.4-0.2
Incentive Sensitization - Breakpoint0.20.20.7-0.40.4-0.4-0.40.4-0.90.3-0.5-0.5-0.2
Progressive ratio test 1 active lever presses1.71.73.61.3-1.31.21.3-1.11.9-1.11.31.11.3
Progressive ratio test 1 breakpoint1.91.94.81.3-1.41.11.4-1.22.2-1.11.31.11.4
Progressive ratio test 1 inactive lever presses0.00.00.10.1-0.1-0.00.1-0.30.1-0.20.0-0.10.3
Progressive ratio test 2 active lever presses0.60.60.90.8-0.80.70.8-0.60.7-0.80.70.61.0
Progressive ratio test 2 breakpoint0.20.20.50.3-0.30.10.4-0.40.6-0.60.20.00.7
Progressive ratio test 2 inactive lever presses0.40.51.00.5-0.50.30.7-1.00.9-1.00.40.50.9
Total sessions with >9 infusions0.70.82.10.3-0.4-0.00.7-1.31.0-1.40.10.41.2
Short access day 1 total inactive lever presses0.10.10.30.1-0.10.10.2-0.3-0.1-0.50.10.30.3
Short access day 10 total inactive lever presses0.10.10.40.3-0.30.50.10.3-0.60.60.40.1-0.1
Short access day 1 total infusions1.11.23.00.7-0.80.31.1-1.60.8-1.70.50.51.7
Short access day 10 total infusions1.11.21.61.0-1.00.91.1-1.31.2-1.20.91.01.2
Short access total infusions2.02.24.11.2-1.30.81.6-2.01.8-1.81.01.02.0
Short access day 1 locomotion0.10.10.2-0.30.3-0.4-0.1-0.10.1-0.2-0.4-0.40.1
Short access day 10 total locomotion1.31.52.6-1.11.1-0.7-1.31.5-1.41.6-1.0-0.8-1.3
Short access total locomotion0.20.20.2-0.40.4-0.5-0.40.30.40.5-0.4-0.4-0.2
Compulsive drug intake0.20.20.30.4-0.40.30.5-0.50.4-0.60.40.20.6
One hour access (0.3 mA shock)0.60.71.10.7-0.70.70.8-0.80.8-1.00.70.90.9
One hour access (shock baseline)0.30.31.00.5-0.50.70.4-0.40.1-0.40.61.00.2
Number of responses in last shaping day0.80.80.9-0.90.9-0.9-0.91.0-0.90.7-0.9-0.8-0.8
Context. condit. distance diff. score0.20.20.30.5-0.50.50.5-0.20.5-0.30.50.40.5
Locomotion velocity, session 10.10.10.4-0.10.1-0.40.2-0.30.2-0.3-0.3-0.70.5
Locomotion distance, session 10.30.41.2-0.70.7-1.1-0.3-0.10.3-0.0-0.9-1.0-0.0
Locomotion velocity, session 21.61.94.3-1.51.5-1.8-1.10.8-0.90.8-1.7-2.1-0.6
Locomotion distance, session 22.73.86.8-2.32.2-2.6-1.91.3-0.31.4-2.4-2.4-1.5
Locomotion velocity, session 35.36.27.1-2.52.5-2.4-2.62.5-2.02.6-2.4-2.5-2.7
Locomotion distance, session 30.10.10.3-0.30.3-0.3-0.30.4-0.30.5-0.2-0.3-0.6
Stereotopy head waving bouts, day 35.46.47.8-2.82.8-2.7-2.72.6-1.62.3-2.8-2.5-2.4
Stereotopy head waving duration, day 33.44.14.9-2.22.2-2.1-2.21.9-1.81.7-2.2-2.1-1.9
Locomotion velocity, session 70.10.10.2-0.40.3-0.4-0.2-0.1-0.40.1-0.4-0.4-0.0
Locomotion distance, session 70.10.20.40.4-0.40.60.3-0.40.1-0.20.50.60.1
Stereotopy head waving bouts, day 71.11.22.2-1.21.2-1.4-1.01.1-0.01.0-1.3-1.5-0.7
Stereotopy head waving duration, day 71.01.22.5-1.21.2-1.5-0.91.00.20.9-1.3-1.6-0.5
Locomotion velocity, session 81.72.14.4-1.61.6-2.0-1.20.9-0.30.9-1.8-2.1-0.9
Locomotion distance, session 80.40.61.0-0.90.8-1.0-0.70.60.30.6-0.9-0.9-0.7
Degree of sensitization distance0.70.71.10.8-0.80.80.8-1.00.8-1.00.80.80.9
Degree of sensitization stereotypy0.10.10.60.0-0.1-0.20.30.00.8-0.0-0.1-0.40.4
Condit. Reinf. active minus inactive responses2.02.32.6-1.61.6-1.6-1.61.4-1.11.3-1.6-1.6-1.6
Condit. Reinf. active-inactive response ratio0.30.30.9-0.40.4-0.4-0.50.5-1.00.5-0.3-0.5-0.7
Condit. Reinf. active responses2.83.44.6-2.12.1-2.1-1.91.6-0.81.5-2.1-2.0-1.7
Condit. Reinf. inactive responses1.51.72.9-1.61.6-1.6-1.30.90.21.1-1.7-1.4-1.0
Incentive salience index mean1.41.72.7-1.51.5-1.6-1.31.1-0.60.9-1.5-1.5-1.2
Condit. Reinf. lever presses0.50.71.7-1.00.9-1.3-0.50.30.50.2-1.2-1.3-0.2
Time in familiar zone, hab. session 14.74.46.5-2.22.2-2.0-2.32.0-1.62.3-2.0-1.8-2.6
Time in novel zone, hab. session 13.23.15.31.7-1.71.42.0-1.91.6-2.11.41.22.3
Total zone transitions, hab. session 10.60.81.8-1.11.0-1.3-0.70.20.20.4-1.2-1.2-0.5
Total locomotion distance, hab. session 11.92.85.5-1.91.9-2.3-1.51.0-0.31.0-2.2-2.1-1.1
Locomotion velocity, hab. session 12.02.95.1-2.01.9-2.3-1.61.1-0.61.2-2.1-2.2-1.3
Time in familiar zone, hab. session 24.54.76.2-2.12.1-1.8-2.42.3-2.22.3-1.9-1.9-2.5
Time in novel zone, hab. session 25.15.17.12.2-2.21.82.5-2.62.1-2.61.91.92.7
Total zone transitions, hab. session 20.40.51.30.3-0.4-0.20.8-1.10.8-1.10.1-0.11.0
Total locomotion distance, hab. session 20.50.71.5-0.90.9-1.2-0.60.4-0.00.3-1.1-1.2-0.4
Locomotion velocity, hab. session 20.60.81.9-1.01.0-1.4-0.70.40.10.3-1.2-1.4-0.4
Novel to familiar place preference ratio2.32.44.31.4-1.50.81.8-2.01.6-2.11.21.11.7
Novelty place preference1.51.63.11.1-1.10.51.5-1.71.3-1.80.90.81.4
Time in novel zone, NPP test2.12.24.01.4-1.40.81.7-2.01.3-2.01.21.01.6
Total zone transitions, NPP test0.30.41.20.4-0.4-0.00.6-0.91.1-0.80.20.20.7
Total locomotion distance, NPP test0.10.20.7-0.20.1-0.50.2-0.40.8-0.5-0.3-0.40.4
Locomotion velocity, NPP test0.20.20.6-0.50.4-0.8-0.2-0.00.6-0.1-0.6-0.70.1
Pavlov. Cond. lever latency0.20.20.50.5-0.50.60.20.2-0.20.40.70.6-0.1
Pavlov. Cond. magazine entry latency1.41.92.4-1.51.5-1.2-1.61.4-1.01.3-1.4-1.3-1.5
Pavlov. Cond. change in total contacts0.20.20.50.3-0.40.30.4-0.60.4-0.70.30.40.4
Pavlov. Cond. index score0.50.71.2-1.01.0-1.0-0.80.5-0.30.3-1.1-1.1-0.6
Pavlov. Cond. latency score0.60.81.5-1.11.1-1.2-0.80.5-0.20.3-1.2-1.2-0.6
Pavlov. Cond. lever contacts0.20.20.5-0.50.4-0.7-0.1-0.30.5-0.5-0.7-0.70.2
Pavlov. Cond. magazine entry number0.50.60.90.9-0.90.80.9-0.80.2-0.70.90.80.8
Pavlov. Cond. intertrial magazine entries0.10.10.6-0.00.00.1-0.20.5-0.30.80.10.2-0.6
Pavlov. Cond. lever-magazine prob. diff.0.60.81.3-1.11.1-1.1-0.90.5-0.40.4-1.1-1.1-0.7
Pavlov. Cond. response bias0.70.91.2-1.11.1-1.0-1.10.7-0.40.7-1.1-1.1-1.0
Bone: apparent density0.30.51.3-0.50.4-1.10.1-0.60.5-0.8-0.8-1.10.9
Bone surface0.71.33.8-1.11.0-1.9-0.2-0.50.5-0.6-1.5-1.80.8
Bone volume0.71.23.2-0.90.8-1.8-0.0-0.70.5-0.8-1.3-1.71.1
Bone: connectivity density0.20.30.7-0.40.3-0.80.1-0.40.3-0.5-0.6-0.90.6
Bone: cortical apparent density1.51.92.91.4-1.41.41.4-1.30.7-1.71.41.31.6
Bone: cortical area1.11.64.00.9-0.90.51.3-2.01.2-1.90.70.51.8
Bone: cortical porosity0.10.10.3-0.20.2-0.4-0.0-0.5-0.2-0.3-0.3-0.40.1
Bone: cortical porosity0.20.31.10.1-0.2-0.10.4-1.10.2-0.9-0.0-0.10.6
Bone: cortical thickness1.72.84.91.5-1.51.31.7-2.21.5-2.21.31.21.9
Bone: cortical thickness0.91.11.41.1-1.11.21.0-1.10.5-1.21.21.10.6
Bone: cortical tissue density1.01.32.11.2-1.21.21.2-1.00.5-1.41.21.11.4
Bone: elastic displacement0.00.00.1-0.00.00.00.00.1-0.3-0.2-0.1-0.00.3
Bone: elastic work0.70.91.90.8-0.80.61.0-1.40.7-1.30.70.51.3
Bone: endosteal estimation0.61.33.01.1-1.10.81.3-1.40.8-1.10.90.91.7
Bone: endosteal perimeter0.20.41.2-0.80.7-1.1-0.5-0.4-0.3-0.1-0.9-0.80.0
Bone: final force2.74.47.21.9-1.91.42.3-2.72.2-2.51.71.52.6
Bone: final moment2.64.27.01.8-1.91.32.2-2.62.1-2.51.61.42.5
Bone: marrow area0.51.12.71.0-1.00.71.2-1.30.7-1.00.80.81.6
Bone: maximum diameter0.40.71.7-0.90.9-1.3-0.5-0.1-0.40.1-1.1-1.20.0
Bone: maximum force2.95.18.62.1-2.11.72.4-2.92.0-2.71.91.72.7
Bone: maximum moment2.84.98.42.0-2.11.62.4-2.91.8-2.71.81.62.7
Bone: minimum diameter0.30.51.40.4-0.40.10.7-1.10.4-1.20.2-0.01.2
Bone: periosteal estimation1.02.14.91.1-1.20.71.6-2.11.3-1.90.80.72.2
Bone: periosteal perimeter0.20.41.4-0.20.1-0.60.2-1.20.5-0.9-0.4-0.40.8
Bone: post-yield work0.30.40.70.7-0.80.50.7-0.5-0.2-0.40.70.40.8
Bone: stiffness4.67.210.02.6-2.72.22.9-3.22.4-3.02.42.23.0
Bone: tissue strength4.74.66.52.1-2.11.82.3-2.41.5-2.42.02.02.5
Bone: trabecular number0.81.33.2-1.31.3-1.6-0.90.6-0.10.5-1.5-1.8-0.5
Bone: trabecular spacing0.70.92.61.0-0.91.50.40.1-0.50.11.31.6-0.2
Bone: trabecular thickness0.80.91.8-0.50.4-1.30.3-1.00.8-1.1-0.9-1.41.1
Bone: trabecular tissue density6.08.410.13.2-3.23.23.0-2.81.5-2.83.23.12.7
Breakpoint value in progressive ratio session2.22.43.3-1.51.5-1.3-1.61.7-1.21.8-1.4-1.6-1.8
Distance traveled before self-admin0.80.91.5-1.11.1-1.2-1.00.4-0.90.7-1.1-0.8-1.0
Distance traveled after self-admin0.20.20.4-0.50.5-0.6-0.4-0.1-0.5-0.0-0.5-0.2-0.3
Delta time in closed arm before/after self-admin1.41.43.11.3-1.31.80.9-0.4-0.7-0.31.61.80.3
Delta time in open arm before/after self-admin1.01.02.11.0-1.00.61.1-1.01.5-1.00.90.61.0
Diff in mean of infusions in LGA sessions1.92.13.0-1.51.5-1.3-1.61.3-1.01.7-1.4-1.4-1.6
Extinction: sum of active levers before priming3.03.15.2-1.61.6-1.2-1.92.2-1.32.2-1.3-1.4-2.3
Active lever presses in extinction session 61.31.21.6-1.21.2-1.3-1.20.80.31.0-1.2-1.2-1.2
Delta distance traveled before/after self-admin0.00.00.10.2-0.20.20.2-0.2-0.0-0.30.1-0.00.3
Delta ambulatory time before/after self-admin0.10.10.20.1-0.10.00.2-0.40.3-0.4-0.0-0.00.4
Time in closed arm before self-admin0.20.21.00.1-0.1-0.20.3-0.21.0-0.6-0.1-0.30.8
Time in closed arm after self-admin0.40.40.70.6-0.60.60.6-0.7-0.8-0.80.60.70.8
Time in open arm before self-admin0.10.10.6-0.30.30.0-0.40.1-0.80.2-0.20.3-0.5
Time in open arm after self-admin1.31.52.61.2-1.21.21.1-1.11.6-1.01.31.40.8
Sum of active levers in priming session hrs 5-60.30.30.5-0.50.5-0.5-0.50.2-0.40.5-0.5-0.4-0.7
Time to tail flick, vehicle, before self-admin1.81.83.1-1.51.5-1.7-1.10.7-1.80.4-1.7-1.7-0.5
Time to tail flick, vehicle, after self-admin0.40.41.4-0.30.3-0.1-0.60.9-0.51.2-0.2-0.5-0.8
Time to tail flick, test, before self-admin1.21.22.0-1.21.2-1.3-1.01.1-0.50.7-1.4-1.4-0.6
Time to tail flick, test, after self-admin0.10.20.4-0.50.4-0.6-0.2-0.2-0.1-0.2-0.6-0.50.1
Delta time to tail flick, vehicle, before/after SA1.11.12.21.2-1.21.50.8-0.31.30.11.41.20.2
Delta time to tail flick, test, before/after SA0.10.00.2-0.10.10.1-0.20.1-0.20.30.00.2-0.5
Ambulatory time before self-admin0.20.20.4-0.50.5-0.7-0.50.1-0.60.2-0.5-0.3-0.5
Ambulatory time after self-admin0.00.00.1-0.20.2-0.3-0.1-0.3-0.1-0.3-0.2-0.0-0.1
Total heroin consumption2.32.83.8-1.81.8-1.8-1.81.3-0.61.6-1.8-2.0-1.7
Area under the delay curve0.00.00.0-0.00.0-0.20.1-0.10.1-0.2-0.1-0.10.2
Delay disc. indifference point, 0s delay1.31.43.60.7-0.80.31.2-1.71.9-1.60.50.41.4
Delay disc. indifference point, 16s delay0.30.30.3-0.60.6-0.5-0.50.5-0.40.5-0.6-0.5-0.5
Delay disc. indifference point, 2s delay0.20.20.60.2-0.20.00.4-0.50.5-0.80.10.10.6
Delay disc. indifference point, 24s delay0.30.31.20.4-0.50.30.5-0.71.1-0.50.40.50.5
Delay disc. indifference point, 4s delay0.40.40.9-0.80.8-1.0-0.60.3-0.10.3-0.9-0.9-0.2
Delay disc. indifference point, 8s delay0.10.10.20.3-0.30.40.2-0.1-0.1-0.10.40.40.2
Delay discount exponential model param0.00.00.00.1-0.10.20.00.0-0.00.10.10.2-0.2
Delay discount hyperbolic model param0.00.00.1-0.10.10.1-0.20.2-0.20.3-0.00.0-0.4
Fecal boli incidents, locomotor time 10.70.81.41.0-1.01.20.8-0.20.8-0.41.11.00.6
Change in fecal boli incidents, locomotor task0.70.61.5-1.00.9-1.2-0.70.2-0.50.2-1.1-0.9-0.4
Time >=10cm from walls, locomotor time 10.70.81.70.6-0.60.30.8-1.11.3-1.20.40.51.1
Bouts of movement, locomotor time 10.40.50.7-0.70.7-0.5-0.80.7-0.10.9-0.6-0.8-0.7
Total resting periods, locomotor time 11.11.21.7-1.21.2-1.0-1.21.1-0.41.2-1.1-1.3-1.1
Rest time, locomotor task time 10.50.50.8-0.80.8-0.8-0.80.50.00.6-0.9-0.9-0.6
Distance moved, locomotor task time 10.60.71.50.7-0.70.30.9-1.20.7-1.20.50.61.1
Vertical activity count, locomotor time 11.21.31.81.2-1.31.11.2-1.2-0.1-1.21.21.31.0
Time >=10cm from walls, locomotor time 21.31.41.91.3-1.31.41.2-0.81.1-0.91.31.31.1
Bouts of movement, locomotor time 20.40.41.0-0.70.7-1.0-0.50.30.00.3-0.9-1.0-0.3
Total resting periods, locomotor time 20.40.41.0-0.70.7-1.0-0.40.20.00.2-0.9-1.0-0.2
Rest time, locomotor task time 20.10.20.6-0.40.4-0.6-0.2-0.10.40.1-0.5-0.80.0
Distance moved, locomotor task time 20.10.10.50.4-0.40.50.20.10.0-0.00.50.7-0.1
Vertical activity count, locomotor time 21.41.52.71.5-1.51.51.2-0.70.3-0.81.61.60.7
Weight adjusted by age0.00.00.10.2-0.20.40.00.10.10.10.30.2-0.1
Seeking ratio, delayed vs. immediate footshock1.21.42.3-1.31.3-1.5-1.20.7-1.10.8-1.4-1.3-0.8
Locomotion in novel chamber0.40.40.70.6-0.60.70.6-0.80.2-0.60.60.80.7
Locomotion in novel chamber post-restriction3.23.84.8-2.12.1-1.9-2.12.0-1.22.1-2.0-1.6-2.2
Progressive ratio1.11.31.81.3-1.31.31.2-0.90.1-0.91.31.31.1
Food seeking constrained by brief footshock1.62.03.0-1.61.5-1.4-1.61.3-0.61.3-1.5-1.4-1.7
Seeking ratio, punishment vs. effort2.32.83.5-1.91.8-1.7-1.91.5-0.41.6-1.8-1.7-1.9
Run reversals in cocaine runway, females1.61.62.4-1.51.5-1.3-1.40.8-0.90.8-1.5-1.2-1.3
Run reversals in cocaine runway, males2.42.33.1-1.71.7-1.7-1.61.3-0.91.3-1.8-1.8-1.3
Latency to leave start box in cocaine runway0.20.20.7-0.10.0-0.50.3-0.60.8-0.5-0.3-0.30.7
Latency to leave start box in cocaine runway, F0.50.51.7-0.10.0-0.60.4-0.91.3-0.9-0.4-0.51.0
Latency to leave start box in cocaine runway, M0.10.10.70.3-0.30.30.10.2-0.80.40.40.3-0.2
Cd content in liver0.50.61.40.6-0.70.70.7-0.81.2-0.70.70.90.6
Co content in liver1.11.31.9-1.11.1-0.8-1.31.3-1.11.2-0.9-1.0-1.4
Cu content in liver1.21.43.30.9-0.90.81.3-1.80.4-1.80.70.61.5
Fe content in liver0.60.71.00.9-0.91.00.8-0.60.6-0.81.00.90.6
K content in liver0.50.51.2-0.80.8-1.0-0.60.2-0.20.5-0.9-1.1-0.4
Mg content in liver0.40.51.0-0.80.8-1.0-0.50.00.70.3-0.9-0.9-0.1
Mn content in liver0.70.81.9-1.01.0-1.4-0.5-0.41.0-0.0-1.3-1.10.2
Na content in liver0.20.20.50.1-0.10.00.3-0.70.7-0.7-0.0-0.20.4
Rb content in liver0.70.82.10.6-0.70.51.0-1.50.3-1.40.50.61.3
Se content in liver0.10.10.2-0.30.3-0.3-0.2-0.1-0.10.1-0.3-0.5-0.0
Sr content in liver0.30.30.9-0.10.10.1-0.40.7-1.00.80.10.0-0.6
Zn content in liver1.82.04.0-1.11.1-0.6-1.61.9-1.31.8-0.8-1.1-2.0