Hub : Genes

Gls2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative TSS ENSRNOT00000099901 0.06 0.05 4.4e-04 0.05 0.06 0.06 0.06 8.1e-04 4.6e-04 3.3e-04 4.2e-04
2 BLA gene expression ENSRNOG00000031612 0.15 0.09 3.1e-07 0.08 0.13 0.1 0.12 3.2e-05 1.9e-07 3.7e-06 7.8e-07
3 Brain alternative TSS ENSRNOT00000018737 0.04 0.03 4.0e-03 0.03 0.02 0.01 0.02 1.9e-03 8.4e-03 3.1e-02 7.7e-03
4 Brain alternative TSS ENSRNOT00000099901 0.06 0.05 1.1e-04 0.04 0.04 0.04 0.04 7.7e-05 2.3e-04 9.1e-05 1.3e-04
5 Brain alternative TSS ENSRNOT00000018737 0.06 0.04 3.1e-04 0.03 0.03 0.02 0.02 7.0e-04 1.5e-03 5.5e-03 2.4e-03
6 Brain isoform ratio ENSRNOT00000099901 0.09 0.09 1.9e-04 0.06 0.03 0.06 0.06 4.0e-06 5.9e-04 7.0e-06 7.9e-06
7 Brain intron excision ratio chr7:622746:623113 0.04 0.03 3.9e-04 0.02 0.03 0.02 0.02 6.7e-03 7.6e-04 3.0e-03 3.8e-03
8 LHb alternative TSS ENSRNOT00000095875 0.21 0.14 5.5e-03 0.08 0.05 -0 0.12 7.1e-03 2.0e-02 4.1e-01 7.2e-04
9 Liver isoform ratio ENSRNOT00000104921 0.06 0.05 8.1e-04 0.02 0.03 0.03 0.03 1.7e-03 4.9e-04 4.1e-04 6.0e-04
10 Liver mRNA stability ENSRNOG00000031612 0.04 0.03 6.0e-05 0.04 0.04 0.03 0.04 4.3e-05 8.2e-05 1.3e-04 7.7e-05
11 OFC gene expression ENSRNOG00000031612 0.44 0.2 1.9e-06 0.13 0.24 0.21 0.23 5.6e-04 2.4e-06 1.1e-05 2.7e-06
12 PL alternative TSS ENSRNOT00000018737 0.04 0.03 7.5e-03 0.03 0.01 0 0.02 3.4e-03 5.0e-02 1.2e-01 1.6e-02
13 PL alternative TSS ENSRNOT00000018737 0.06 0.05 2.4e-03 0.03 0.02 0.02 0.03 1.2e-03 8.7e-03 6.1e-03 4.0e-03
14 PL gene expression ENSRNOG00000031612 0.15 0.1 7.1e-08 0.07 0.09 0.07 0.07 5.6e-06 1.3e-07 3.2e-06 3.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail6.220.031.64.8-3.35.25.65.25.6-5.40.73.35.0-2.65.25.1-1.9
BMI without tail1.12.33.71.9-1.61.51.31.51.3-1.90.81.21.9-1.41.71.6-1.3
Body weight0.93.96.72.6-1.62.12.22.12.2-2.40.41.42.1-1.22.32.2-1.0
Epididymis fat weight0.10.32.4-0.2-0.1-0.6-0.2-0.6-0.10.40.4-1.6-0.2-0.2-0.6-0.6-0.2
Glucose1.42.23.21.8-1.21.61.51.61.4-1.80.31.81.6-0.91.71.8-0.7
Heart weight0.10.10.30.1-0.50.2-0.40.2-0.3-0.20.50.10.6-0.5-0.10.2-0.5
Left kidney weight0.41.03.7-0.41.10.90.00.90.2-0.3-1.61.9-0.41.40.80.91.4
Right kidney weight0.30.81.8-1.31.1-0.5-0.8-0.5-0.80.8-0.90.6-1.21.1-0.5-0.41.0
Tail length4.112.423.6-3.11.8-4.4-4.8-4.4-4.94.00.3-3.3-3.71.1-4.1-4.20.6
Length with tail1.55.59.6-2.11.8-2.7-3.0-2.7-3.12.7-0.6-2.0-2.81.4-2.5-2.61.1
Length without tail0.20.51.00.10.60.80.70.80.7-0.4-1.00.8-0.00.80.70.70.9
Liver weight, left1.32.13.51.5-1.61.41.51.41.7-1.80.90.51.9-1.41.51.5-1.2
Liver weight, right0.81.33.31.0-0.81.40.81.40.8-1.40.11.81.2-0.51.51.3-0.5
Parametrial fat weight0.10.21.60.0-0.2-0.3-0.2-0.3-0.00.20.3-1.30.2-0.3-0.4-0.5-0.2
Retroperitoneal fat weight1.86.09.33.0-2.32.72.42.72.4-3.10.92.12.8-1.92.72.7-1.7
Intraocular pressure0.71.02.30.1-0.6-1.1-1.0-1.1-1.00.71.2-1.5-0.4-0.8-1.1-1.1-1.0
Extensor digitorum longus weight4.417.727.35.2-4.34.34.24.34.1-5.02.23.74.9-3.64.44.4-3.4
Soleus weight5.014.722.54.3-3.04.34.14.34.1-4.50.84.74.0-2.24.44.4-2.0
Tibialis anterior weight0.93.04.82.2-1.42.01.72.01.7-2.20.41.91.5-1.12.12.2-0.9
Tibia length0.92.44.4-1.10.8-2.0-2.0-2.0-2.01.80.1-1.1-1.60.5-1.9-2.10.3
Number of licking bursts2.83.36.02.4-2.11.61.81.61.9-2.11.30.32.4-2.01.71.7-1.8
Food consumed during 24 hour testing period0.30.40.70.8-0.40.70.80.70.8-0.8-0.00.10.7-0.40.80.7-0.2
Times rat made contact with spout1.01.11.91.4-1.30.91.10.91.2-1.20.90.01.1-1.21.00.9-1.1
Mean time between licks in bursts0.60.92.7-1.00.2-1.2-1.0-1.2-0.91.10.4-1.6-0.6-0.1-1.2-1.1-0.1
Mean num. licks in bursts0.60.81.9-1.11.0-0.8-0.9-0.8-0.91.0-0.5-0.2-1.40.9-0.8-0.90.8
Std. dev. time between licks in bursts0.70.92.2-1.41.4-0.5-0.3-0.5-0.30.7-1.5-0.3-0.81.4-0.3-0.31.4
Water consumed over 24 hours1.01.12.20.50.31.31.41.31.5-1.0-1.11.00.50.61.31.30.8
Indifference point 0 sec3.25.210.32.0-1.22.83.12.83.2-2.7-0.22.12.1-0.82.82.8-0.4
Indifference point AUC0.40.51.0-0.60.4-0.9-1.0-0.9-1.00.90.0-0.6-0.80.2-0.9-0.80.2
Indifference point function ln k0.10.20.40.2-0.40.50.50.50.6-0.60.10.50.5-0.20.60.6-0.2
Indifference point function log k0.10.20.40.2-0.40.50.50.50.6-0.60.10.50.5-0.20.60.6-0.2
Delay discounting total patch changes 0 sec3.04.910.02.0-1.32.63.12.63.2-2.6-0.01.92.1-0.92.62.7-0.6
Delay discounting total patch changes 12 sec1.62.13.51.9-1.61.31.61.31.6-1.61.00.41.7-1.51.31.4-1.3
Delay discounting total patch changes 18 sec0.00.00.10.2-0.10.30.30.30.4-0.20.10.20.1-0.10.10.3-0.1
Delay discounting total patch changes 24 sec0.40.51.00.8-0.20.90.90.90.9-0.8-0.21.00.4-0.00.91.00.1
Delay discounting total patch changes 6 sec1.62.54.71.4-1.01.82.11.82.2-1.90.01.41.6-0.71.91.9-0.5
Delay discounting time to switch 0 sec0.20.30.50.40.20.70.50.70.5-0.5-0.60.60.10.40.70.60.5
Delay discounting water rate 0 sec0.61.01.91.1-1.40.60.80.60.8-1.01.00.61.3-1.30.60.8-1.3
Delay discounting water rate 12 sec0.91.32.41.3-1.60.90.90.91.0-1.21.20.61.3-1.50.80.9-1.4
Delay discounting water rate 18 sec1.21.54.70.8-1.8-0.8-0.6-0.8-0.6-0.12.2-1.10.7-2.0-0.5-0.7-2.1
Delay discounting water rate 24 sec2.53.58.92.3-2.90.40.90.40.9-1.42.7-0.62.2-3.00.50.5-3.0
Delay discounting water rate 6 sec0.71.02.1-0.3-0.8-1.1-1.1-1.1-1.10.51.5-1.20.0-1.1-1.0-1.0-1.2
Locomotor activity3.25.18.5-2.62.3-2.4-2.5-2.4-2.42.5-1.2-1.8-2.92.1-1.9-2.21.8
Locomotor testing distance1.22.03.4-1.81.4-1.5-1.4-1.5-1.31.5-0.8-1.2-1.81.3-1.2-1.31.2
Locomotor testing rearing0.10.20.80.1-0.4-0.4-0.4-0.4-0.30.00.5-0.90.1-0.4-0.1-0.2-0.5
Light reinforcement 12.75.07.6-2.72.0-2.5-2.3-2.5-2.22.6-0.7-2.1-2.81.7-2.4-2.31.4
Light reinforcement 20.70.91.6-1.20.8-1.2-0.8-1.2-0.81.1-0.2-1.1-1.00.6-1.1-1.20.6
Reaction time number correct1.01.42.81.7-1.60.81.10.81.2-1.21.2-0.11.3-1.60.80.8-1.4
Reaction time mean minus median1.41.83.3-1.31.1-1.5-1.8-1.5-1.81.5-0.5-0.6-1.71.0-1.3-1.60.6
Reaction time mean minus median AUC2.02.54.9-1.82.2-1.1-1.3-1.1-1.31.6-1.8-0.2-2.12.2-1.0-1.11.9
Reaction time num false alarms0.50.71.31.1-0.90.70.60.70.5-1.00.50.91.0-0.80.80.8-0.8
Reaction time num false alarms AUC0.60.91.91.4-1.20.60.50.60.5-1.10.90.81.1-1.10.80.8-1.2
Reaction time trials correct on left1.01.42.81.7-1.60.81.10.81.2-1.21.2-0.11.3-1.60.80.8-1.4
Reaction time trials on left0.91.32.61.6-1.50.81.20.81.2-1.21.1-0.11.2-1.50.80.8-1.3
Reaction time mean1.11.52.8-1.51.7-0.9-1.1-0.9-1.11.5-1.2-0.2-1.51.6-1.1-1.01.4
Reaction time mean AUC0.60.81.9-1.11.4-0.4-0.6-0.4-0.61.0-1.10.3-1.01.4-0.6-0.51.2
Median of all reaction times0.60.81.8-1.11.3-0.5-0.6-0.5-0.61.0-1.00.0-0.91.3-0.8-0.51.2
Reaction time omissions0.10.10.2-0.30.40.20.20.20.3-0.0-0.50.20.10.40.10.30.4
Reaction time false alarm rate0.10.10.70.4-0.20.30.10.30.0-0.4-0.10.90.3-0.00.40.4-0.1
Reaction time premature initiation rate1.41.93.8-0.8-0.0-1.7-1.9-1.7-2.01.31.0-1.7-0.9-0.3-1.6-1.7-0.6
Reaction time premature initiations1.11.53.40.0-0.9-1.3-1.3-1.3-1.30.71.7-1.8-0.2-1.3-1.2-1.3-1.4
Std. dev. reaction times0.81.11.8-1.21.3-0.9-1.1-0.9-1.21.2-0.9-0.1-1.31.3-0.9-0.91.0
Reaction time trials completed0.91.32.61.6-1.50.81.20.81.2-1.21.1-0.11.2-1.50.80.8-1.3
Reaction time trials AUC1.11.63.11.8-1.70.81.20.81.2-1.31.4-0.21.4-1.80.80.7-1.5
Social response proportion0.80.91.3-1.01.1-0.8-1.0-0.8-1.01.1-0.7-0.4-1.11.0-0.8-0.91.0
Social responses7.49.613.6-3.63.1-3.2-3.3-3.2-3.33.7-1.5-2.3-3.72.6-3.2-3.42.3
Social time0.91.13.11.2-1.11.00.61.00.7-1.20.61.81.1-0.91.11.0-1.0
Conditioned locomotion1.21.53.41.6-1.80.60.70.60.6-1.11.6-0.01.5-1.80.60.5-1.8
Cocaine response after cond. corrected2.32.64.62.0-2.11.41.11.41.0-1.61.60.92.1-2.01.21.2-2.0
Cocaine response after cond. not corrected2.52.85.12.1-2.31.41.11.41.1-1.71.70.82.2-2.21.21.2-2.1
Cocaine response before conditioning0.40.50.9-0.90.8-0.7-0.8-0.7-0.60.8-0.4-0.5-0.90.7-0.6-0.70.7
Saline control response0.30.40.80.9-0.80.50.40.50.4-0.70.40.60.8-0.70.70.6-0.7
Condit. Reinf. active minus inactive responses1.61.93.3-1.30.1-1.7-1.7-1.7-1.71.50.9-1.8-1.0-0.2-1.8-1.8-0.4
Condit. Reinf. active-inactive response ratio1.11.12.9-0.1-0.9-1.0-1.1-1.0-1.20.71.7-1.0-0.1-1.2-1.2-1.2-1.4
Condit. Reinf. active responses0.91.32.0-1.40.7-1.3-1.3-1.3-1.21.40.0-1.3-1.10.5-1.3-1.40.4
Condit. Reinf. inactive responses0.40.41.0-0.91.0-0.4-0.3-0.4-0.20.6-0.9-0.3-0.81.0-0.3-0.41.0
Condit. Reinf. lever presses2.12.95.2-1.40.6-2.2-1.9-2.2-2.01.90.6-2.3-1.50.1-2.1-2.2-0.0
Condit. Reinf. lever reinforcers received0.71.02.0-1.10.4-1.2-1.2-1.2-1.11.20.4-1.4-0.90.1-1.2-1.30.0
Pavlov. Cond. lever latency1.31.82.61.2-1.01.61.51.61.6-1.60.31.31.5-0.81.41.6-0.6
Pavlov. Cond. magazine entry latency2.12.44.3-1.71.3-1.7-1.7-1.7-1.71.8-0.4-2.1-1.61.0-1.7-1.70.9
Pavlov. Cond. change in total contacts0.60.92.2-1.00.5-1.1-1.1-1.1-1.11.00.1-1.5-0.90.3-0.9-1.10.3
Pavlov. Cond. index score1.72.34.2-1.51.0-1.8-1.7-1.8-1.81.7-0.1-2.1-1.50.7-1.6-1.70.6
Pavlov. Cond. latency score1.92.44.1-1.61.3-1.7-1.7-1.7-1.81.8-0.4-2.0-1.71.0-1.6-1.70.9
Pavlov. Cond. lever contacts1.11.52.4-1.10.6-1.6-1.4-1.6-1.51.40.2-1.5-1.20.3-1.4-1.50.2
Pavlov. Cond. magazine entry number1.82.34.41.7-1.31.61.51.61.6-1.70.42.11.5-1.01.61.6-0.9
Pavlov. Cond. intertrial magazine entries0.81.12.01.4-1.30.70.50.70.6-1.10.91.41.1-1.11.00.9-1.2
Pavlov. Cond. lever-magazine prob. diff.1.82.34.0-1.71.2-1.7-1.7-1.7-1.81.7-0.3-2.0-1.60.9-1.6-1.70.8
Pavlov. Cond. response bias1.72.33.6-1.50.8-1.9-1.8-1.9-1.91.80.2-1.9-1.40.5-1.8-1.90.3
Conditioned reinforcement - actives0.30.30.6-0.80.60.40.30.40.2-0.0-0.80.7-0.50.70.30.30.7
Conditioned reinforcement - inactives1.31.42.71.1-1.61.00.81.00.8-1.41.21.01.5-1.51.01.0-1.5
Conditioned locomotion1.72.15.7-2.41.3-1.5-1.1-1.5-1.21.6-0.6-1.4-1.81.1-1.5-1.51.1
Intermittent access intake day 1-15 change0.20.20.4-0.7-0.0-0.5-0.6-0.5-0.70.30.20.1-0.4-0.1-0.4-0.4-0.1
Intermittent access intake escalation0.60.51.60.0-1.0-0.6-0.7-0.6-0.80.11.3-0.00.2-1.1-0.5-0.5-1.2
Intermittent access intake escalation 20.70.71.4-0.4-0.5-1.0-1.1-1.0-1.20.61.0-0.4-0.2-0.7-1.0-1.0-0.8
Intermitt. access day 1 inactive lever presses0.50.61.60.2-1.0-0.5-0.7-0.5-0.6-0.01.3-0.70.5-1.2-0.5-0.5-1.2
Intermitt. access day 15 inactive lever presses0.70.81.6-0.5-0.2-1.2-0.9-1.2-0.90.80.8-1.3-0.5-0.4-1.2-1.2-0.6
Intermitt. access escalation Index0.80.71.9-1.11.20.30.00.30.00.1-1.40.7-0.71.30.40.41.3
Intermittent access day 1 total infusions0.40.41.50.3-0.20.81.20.81.1-0.7-0.20.10.40.00.80.80.1
Intermittent access day 15 total infusions0.20.20.60.2-0.60.40.80.40.6-0.50.40.20.4-0.50.40.4-0.5
Intermittent access terminal intake (last 3 days)0.30.41.0-0.10.10.71.00.70.9-0.5-0.50.70.10.30.80.80.3
Intermittent access total infusions0.40.51.30.5-0.50.81.10.81.0-0.80.10.40.5-0.30.80.8-0.3
Intermittent access day 1 locomotion0.00.00.00.1-0.2-0.00.1-0.0-0.0-0.10.2-0.20.1-0.2-0.0-0.0-0.2
Intermittent access day 15 total locomotion0.20.20.6-0.80.1-0.6-0.5-0.6-0.70.50.20.2-0.30.0-0.5-0.5-0.1
Intermittent access total locomotion0.10.20.3-0.60.4-0.4-0.2-0.4-0.40.5-0.2-0.1-0.50.4-0.4-0.40.3
Intermittent access standard deviation0.10.10.3-0.5-0.3-0.4-0.2-0.4-0.30.20.40.1-0.1-0.3-0.3-0.3-0.4
Cocaine induced anxiety1.61.93.4-1.61.8-1.1-0.9-1.1-0.91.5-1.4-0.7-1.81.8-1.1-1.11.7
Post-drug Anxiety1.21.33.9-1.11.8-0.1-0.1-0.10.00.7-1.90.1-1.21.9-0.1-0.12.0
Baseline Anxiety0.10.10.20.3-0.40.0-0.20.0-0.3-0.10.4-0.00.3-0.40.00.0-0.4
Lifetime Intake1.11.33.20.6-0.41.41.81.41.7-1.2-0.31.00.7-0.11.41.40.0
Incentive Sensitization - Responses0.10.10.2-0.50.2-0.2-0.3-0.2-0.30.3-0.10.3-0.40.2-0.2-0.20.2
Incentive Sensitization - Breakpoint0.20.20.5-0.70.5-0.2-0.4-0.2-0.30.4-0.40.3-0.60.5-0.2-0.20.4
Progressive ratio test 1 active lever presses1.11.11.81.1-0.91.31.01.30.8-1.40.31.01.1-0.71.31.3-0.7
Progressive ratio test 1 breakpoint1.11.22.01.1-0.91.41.01.40.9-1.40.20.91.0-0.61.41.4-0.5
Progressive ratio test 1 inactive lever presses0.10.10.3-0.60.10.3-0.00.3-0.0-0.2-0.30.3-0.00.20.40.40.2
Progressive ratio test 2 active lever presses0.50.61.60.5-0.41.00.81.00.7-0.9-0.11.20.5-0.21.01.0-0.2
Progressive ratio test 2 breakpoint0.30.41.2-0.20.30.70.50.70.5-0.4-0.61.1-0.10.50.80.80.5
Progressive ratio test 2 inactive lever presses0.40.51.20.10.10.91.10.91.1-0.6-0.50.50.30.30.90.90.4
Total sessions with >9 infusions1.21.32.4-0.60.91.21.61.21.4-0.6-1.51.1-0.11.21.31.31.3
Short access day 1 total inactive lever presses0.10.10.3-0.30.10.30.50.30.5-0.2-0.20.40.20.20.30.30.2
Short access day 10 total inactive lever presses0.30.30.90.1-0.8-0.1-0.5-0.1-0.5-0.20.90.40.7-0.9-0.1-0.1-1.0
Short access day 1 total infusions1.92.14.2-0.20.61.71.81.71.7-1.1-1.52.00.21.11.81.81.2
Short access day 10 total infusions0.80.92.60.4-0.41.21.61.21.5-1.1-0.20.60.7-0.21.21.2-0.1
Short access total infusions2.22.45.00.40.12.02.22.02.1-1.5-1.11.80.60.62.02.00.7
Short access day 1 locomotion0.20.30.8-0.80.60.1-0.00.1-0.10.1-0.70.9-0.50.70.20.20.7
Short access day 10 total locomotion1.11.22.1-1.40.2-1.3-1.4-1.3-1.51.20.5-0.6-0.7-0.1-1.4-1.4-0.2
Short access total locomotion0.20.20.7-0.80.5-0.2-0.2-0.2-0.30.3-0.40.2-0.50.5-0.2-0.20.4
Compulsive drug intake0.20.20.30.6-0.10.60.40.60.5-0.4-0.20.50.3-0.00.50.50.0
One hour access (0.3 mA shock)0.50.51.60.6-0.40.91.30.91.2-0.70.00.60.5-0.30.80.8-0.2
One hour access (shock baseline)0.30.30.70.2-0.80.20.80.20.6-0.50.7-0.40.5-0.80.20.2-0.7
Number of responses in last shaping day0.60.61.7-1.30.6-0.8-0.7-0.8-0.80.9-0.2-0.6-1.00.5-0.8-0.70.4
Context. condit. distance diff. score0.20.20.30.5-0.50.50.30.50.1-0.50.30.50.5-0.40.50.5-0.4
Locomotion velocity, session 10.60.72.1-0.11.00.50.40.50.3-0.1-1.41.5-0.41.20.60.61.2
Locomotion distance, session 10.91.13.4-1.01.7-0.00.1-0.00.00.5-1.80.4-1.21.80.10.11.8
Locomotion velocity, session 21.92.25.4-1.82.2-0.6-0.8-0.6-0.71.2-2.10.3-2.02.3-0.6-0.52.2
Locomotion distance, session 22.73.97.4-2.22.7-1.5-1.4-1.5-1.32.1-2.2-1.0-2.72.6-1.5-1.42.5
Locomotion velocity, session 33.94.67.1-2.21.5-2.7-2.5-2.7-2.52.6-0.2-1.8-2.31.1-2.5-2.50.8
Locomotion distance, session 30.10.10.3-0.1-0.0-0.6-0.5-0.6-0.40.30.2-0.2-0.3-0.1-0.4-0.3-0.1
Stereotopy head waving bouts, day 34.35.17.8-2.82.2-2.4-2.3-2.4-2.42.8-1.0-1.9-2.51.8-2.5-2.51.6
Stereotopy head waving duration, day 32.73.26.5-2.61.7-1.9-1.6-1.9-1.72.2-0.8-1.6-2.01.4-1.9-2.01.3
Locomotion velocity, session 70.20.20.5-0.60.6-0.00.1-0.00.00.3-0.6-0.1-0.50.6-0.1-0.00.7
Locomotion distance, session 70.20.30.90.4-0.80.10.30.10.3-0.30.9-0.60.5-0.9-0.00.0-0.8
Stereotopy head waving bouts, day 71.11.32.6-1.21.6-0.7-1.0-0.7-1.01.0-1.40.4-1.41.6-0.6-0.61.6
Stereotopy head waving duration, day 71.11.43.2-1.21.8-0.5-0.9-0.5-1.01.0-1.60.7-1.41.8-0.5-0.51.7
Locomotion velocity, session 81.92.35.3-1.52.3-0.9-0.8-0.9-1.01.3-2.0-0.3-2.02.3-0.7-0.72.2
Locomotion distance, session 80.40.61.1-0.60.9-0.7-0.5-0.7-0.70.8-0.7-0.7-1.00.9-0.6-0.60.8
Degree of sensitization distance0.50.51.00.6-0.40.91.00.90.9-0.80.00.00.7-0.30.80.8-0.2
Degree of sensitization stereotypy0.30.41.60.10.60.4-0.00.4-0.0-0.2-1.01.3-0.20.80.50.40.8
Condit. Reinf. active minus inactive responses1.71.93.0-1.71.2-1.6-1.4-1.6-1.51.6-0.4-1.7-1.60.9-1.5-1.30.8
Condit. Reinf. active-inactive response ratio0.40.41.6-0.5-0.1-0.7-0.7-0.7-0.70.50.5-1.3-0.4-0.2-0.6-0.6-0.3
Condit. Reinf. active responses2.63.25.2-2.32.0-1.7-1.6-1.7-1.72.0-1.3-1.5-2.11.8-1.6-1.51.7
Condit. Reinf. inactive responses1.61.93.6-1.71.9-1.0-1.0-1.0-1.11.4-1.5-0.6-1.71.8-1.0-1.01.7
Incentive salience index mean1.31.62.8-1.61.6-1.2-1.0-1.2-1.11.4-1.1-0.8-1.71.5-1.0-0.91.4
Condit. Reinf. lever presses1.11.44.2-1.01.9-0.2-0.2-0.2-0.20.7-2.00.7-1.52.1-0.1-0.02.0
Time in familiar zone, hab. session 14.64.411.1-1.81.0-2.6-2.3-2.6-2.22.30.3-3.3-2.10.5-2.5-2.50.4
Time in novel zone, hab. session 13.53.48.51.2-0.12.32.12.32.0-1.9-1.12.91.50.42.32.30.5
Total zone transitions, hab. session 10.81.12.9-1.01.7-0.5-0.4-0.5-0.30.9-1.60.2-1.21.7-0.4-0.41.7
Total locomotion distance, hab. session 12.43.47.7-2.12.8-1.1-0.9-1.1-1.01.6-2.50.1-2.32.8-0.9-0.82.7
Locomotion velocity, hab. session 12.13.06.1-2.02.5-1.3-1.1-1.3-1.11.7-2.1-0.4-2.22.4-1.1-1.02.3
Time in familiar zone, hab. session 24.04.29.3-1.80.6-2.5-2.3-2.5-2.32.30.8-3.1-1.70.1-2.6-2.6-0.1
Time in novel zone, hab. session 24.64.68.51.8-0.52.72.72.72.6-2.4-1.02.91.80.12.82.70.3
Total zone transitions, hab. session 21.11.43.40.01.11.01.21.01.2-0.6-1.91.6-0.21.41.21.21.5
Total locomotion distance, hab. session 20.70.92.4-0.91.5-0.4-0.2-0.4-0.20.7-1.50.3-1.21.5-0.3-0.31.4
Locomotion velocity, hab. session 20.91.33.5-1.01.8-0.4-0.2-0.4-0.20.8-1.80.4-1.41.9-0.3-0.31.8
Novel to familiar place preference ratio2.32.44.91.20.11.72.01.72.0-1.7-1.31.60.90.62.12.20.8
Novelty place preference1.61.73.50.90.31.41.71.41.7-1.3-1.31.10.70.61.71.90.8
Time in novel zone, NPP test2.02.14.41.10.01.62.01.61.9-1.6-1.11.30.90.42.02.10.6
Total zone transitions, NPP test0.30.50.90.50.40.70.90.71.0-0.5-1.00.70.00.60.80.70.7
Total locomotion distance, NPP test0.40.61.9-0.11.00.40.60.40.6-0.0-1.40.8-0.51.20.40.51.2
Locomotion velocity, NPP test0.40.51.8-0.31.20.10.20.10.20.3-1.30.6-0.81.30.10.11.3
Pavlov. Cond. lever latency0.50.61.80.6-1.2-0.1-0.4-0.1-0.4-0.31.4-0.40.7-1.3-0.1-0.2-1.3
Pavlov. Cond. magazine entry latency1.21.52.6-1.40.7-1.5-1.3-1.5-1.31.50.1-1.5-1.20.5-1.6-1.40.3
Pavlov. Cond. change in total contacts0.20.20.50.1-0.10.40.70.40.7-0.4-0.20.10.20.00.40.70.0
Pavlov. Cond. index score0.50.61.3-1.01.1-0.6-0.3-0.6-0.30.9-0.9-0.5-1.01.1-0.6-0.41.0
Pavlov. Cond. latency score0.70.92.2-1.21.5-0.6-0.3-0.6-0.20.9-1.3-0.2-1.11.5-0.5-0.41.4
Pavlov. Cond. lever contacts0.70.82.6-0.51.30.20.50.20.50.3-1.60.7-0.71.50.20.41.5
Pavlov. Cond. magazine entry number0.40.50.90.8-0.60.80.60.80.6-0.90.10.80.8-0.50.90.7-0.3
Pavlov. Cond. intertrial magazine entries0.30.40.90.1-0.6-0.6-0.8-0.6-0.70.11.0-0.80.1-0.8-0.4-0.4-0.9
Pavlov. Cond. lever-magazine prob. diff.0.60.81.4-1.11.2-0.7-0.4-0.7-0.41.0-0.9-0.7-1.11.1-0.7-0.51.0
Pavlov. Cond. response bias0.60.81.6-0.90.8-1.0-0.7-1.0-0.71.1-0.3-1.3-1.00.6-1.0-0.80.5
Bone: apparent density1.52.46.7-0.92.10.90.60.90.60.1-2.62.2-1.12.40.90.82.5
Bone surface2.85.014.6-2.03.30.80.50.80.50.5-3.82.3-2.03.70.90.83.8
Bone volume3.05.114.4-1.83.21.10.71.10.70.3-3.82.8-1.83.61.21.13.7
Bone: connectivity density0.91.43.8-0.81.60.60.40.60.40.1-1.91.8-0.81.80.60.51.9
Bone: cortical apparent density1.51.94.51.2-1.01.61.71.61.5-1.50.22.11.5-0.71.51.4-0.7
Bone: cortical area1.32.03.30.20.61.81.81.81.8-1.2-1.51.50.51.01.81.71.2
Bone: cortical porosity0.20.20.6-0.50.60.10.30.10.50.1-0.7-0.6-0.40.70.20.30.8
Bone: cortical porosity0.50.51.1-0.30.70.60.90.61.1-0.3-1.0-0.2-0.20.90.70.81.0
Bone: cortical thickness1.42.34.80.9-0.41.92.21.92.1-1.7-0.61.41.40.01.91.80.2
Bone: cortical thickness0.70.81.41.0-1.10.61.10.61.1-1.10.7-0.31.2-1.00.90.8-0.9
Bone: cortical tissue density1.11.43.91.1-0.91.41.41.41.2-1.20.22.01.3-0.61.21.2-0.7
Bone: elastic displacement0.10.10.9-0.30.20.30.10.30.10.0-0.30.90.00.20.00.00.3
Bone: elastic work0.70.91.70.50.11.31.31.31.3-0.9-0.71.00.60.31.11.00.4
Bone: endosteal estimation0.71.43.80.40.01.71.11.71.1-1.2-0.82.00.60.31.61.60.5
Bone: endosteal perimeter0.40.82.4-1.31.40.00.00.0-0.00.6-1.3-0.6-1.01.4-0.10.11.6
Bone: final force2.23.76.71.4-0.22.62.52.62.5-2.2-1.01.91.20.32.62.50.6
Bone: final moment2.13.56.41.3-0.22.52.42.52.4-2.1-1.11.91.10.32.52.40.6
Bone: marrow area0.61.33.50.40.01.61.01.60.9-1.1-0.71.90.50.31.51.50.5
Bone: maximum diameter0.71.33.6-1.51.80.0-0.10.0-0.20.6-1.80.4-1.31.90.0-0.01.9
Bone: maximum force2.44.17.51.6-0.42.72.72.72.6-2.3-0.91.91.50.02.72.60.4
Bone: maximum moment2.34.17.41.5-0.42.72.62.72.6-2.3-0.91.91.40.12.72.50.4
Bone: minimum diameter0.50.91.9-0.20.61.21.01.20.9-0.6-1.11.40.10.91.11.11.0
Bone: periosteal estimation1.32.75.20.30.62.21.82.21.7-1.4-1.62.30.51.02.12.11.2
Bone: periosteal perimeter0.61.02.7-0.91.30.80.90.80.8-0.1-1.60.2-0.41.50.70.81.6
Bone: post-yield work0.30.51.90.7-0.50.80.40.80.3-0.80.11.40.5-0.30.80.8-0.3
Bone: stiffness3.55.69.72.2-1.13.03.03.03.0-2.9-0.52.02.1-0.53.13.0-0.2
Bone: tissue strength3.83.76.51.7-1.02.52.52.52.4-2.2-0.22.11.7-0.62.32.3-0.3
Bone: trabecular number1.11.74.4-1.42.1-0.5-0.6-0.5-0.51.1-1.90.6-1.62.1-0.4-0.52.1
Bone: trabecular spacing1.82.36.81.3-2.4-0.2-0.1-0.2-0.1-0.62.6-1.21.5-2.6-0.3-0.2-2.6
Bone: trabecular thickness3.44.112.6-1.22.71.11.11.11.0-0.1-3.52.4-1.33.11.41.33.3
Bone: trabecular tissue density4.96.89.73.0-2.72.72.92.72.7-3.11.31.83.1-2.32.82.8-2.1
Breakpoint value in progressive ratio session1.82.03.7-1.20.6-1.8-1.8-1.8-1.81.60.2-1.9-1.10.3-1.7-1.70.1
Distance traveled before self-admin0.80.81.3-1.00.9-1.0-0.6-1.0-0.51.1-0.5-1.0-1.20.7-0.9-1.10.8
Distance traveled after self-admin0.20.20.4-0.60.6-0.30.1-0.30.00.5-0.4-0.1-0.60.5-0.3-0.40.5
Delta time in closed arm before/after self-admin2.12.15.81.6-2.30.30.40.30.4-1.02.3-0.11.8-2.40.30.3-2.4
Delta time in open arm before/after self-admin0.80.81.51.2-0.31.00.91.01.0-1.1-0.31.00.6-0.11.21.1-0.0
Diff in mean of infusions in LGA sessions1.71.94.1-1.40.8-1.6-1.5-1.6-1.51.6-0.0-2.0-1.30.5-1.6-1.60.4
Extinction: sum of active levers before priming3.13.16.3-1.10.1-2.3-2.3-2.3-2.21.81.1-2.5-1.1-0.4-2.3-2.2-0.5
Active lever presses in extinction session 61.21.12.4-1.11.1-1.2-0.8-1.2-0.81.2-0.5-1.5-1.20.9-1.1-1.20.8
Delta distance traveled before/after self-admin0.10.10.6-0.0-0.00.30.20.30.1-0.2-0.20.70.10.10.30.20.1
Delta ambulatory time before/after self-admin0.20.20.7-0.20.40.40.40.40.3-0.2-0.60.9-0.00.50.40.40.5
Time in closed arm before self-admin0.50.61.6-0.10.80.80.30.80.4-0.2-1.31.2-0.21.10.70.71.1
Time in closed arm after self-admin0.40.52.00.3-0.30.80.80.80.7-0.6-0.01.40.6-0.20.70.7-0.1
Time in open arm before self-admin0.30.32.0-0.6-0.2-0.5-0.1-0.5-0.20.40.5-1.40.1-0.4-0.5-0.6-0.4
Time in open arm after self-admin0.90.91.71.3-1.10.81.10.81.1-1.20.7-0.11.1-1.00.90.9-0.9
Sum of active levers in priming session hrs 5-60.30.20.8-0.40.3-0.7-0.3-0.7-0.30.60.1-0.9-0.20.1-0.6-0.70.2
Time to tail flick, vehicle, before self-admin2.22.25.1-2.22.2-0.5-0.6-0.5-0.61.2-2.00.8-1.72.3-0.6-0.52.2
Time to tail flick, vehicle, after self-admin0.70.83.10.0-0.5-0.8-1.1-0.8-1.30.51.0-1.8-0.1-0.7-0.8-0.8-0.8
Time to tail flick, test, before self-admin1.31.32.9-1.51.6-0.6-1.0-0.6-0.91.0-1.40.2-1.31.7-0.6-0.51.5
Time to tail flick, test, after self-admin0.50.51.7-0.71.10.10.20.10.10.3-1.20.4-0.81.20.10.11.3
Delta time to tail flick, vehicle, before/after SA1.81.84.42.0-2.00.20.10.20.0-0.92.0-1.21.5-2.10.20.2-2.1
Delta time to tail flick, test, before/after SA0.30.31.00.3-0.4-0.5-0.2-0.5-0.30.20.7-1.0-0.1-0.6-0.5-0.5-0.5
Ambulatory time before self-admin0.30.31.4-0.50.5-0.5-0.2-0.5-0.20.5-0.2-1.2-0.60.3-0.5-0.50.4
Ambulatory time after self-admin0.10.10.1-0.30.3-0.10.2-0.10.20.2-0.3-0.2-0.30.3-0.0-0.20.4
Total heroin consumption2.12.54.7-1.61.5-1.7-1.5-1.7-1.51.8-0.7-2.2-1.61.2-1.7-1.71.2
Area under the delay curve0.10.10.20.20.30.20.10.20.2-0.0-0.40.3-0.20.40.20.20.4
Delay disc. indifference point, 0s delay1.61.73.40.70.71.41.71.41.8-1.0-1.70.90.31.11.61.61.3
Delay disc. indifference point, 16s delay0.20.20.4-0.50.4-0.5-0.5-0.5-0.50.5-0.2-0.6-0.60.4-0.5-0.50.4
Delay disc. indifference point, 2s delay0.30.40.80.40.50.60.60.60.7-0.3-0.80.9-0.00.60.60.60.7
Delay disc. indifference point, 24s delay0.20.20.60.7-0.20.50.60.50.6-0.5-0.1-0.10.3-0.10.40.4-0.0
Delay disc. indifference point, 4s delay0.60.61.6-0.81.2-0.2-0.3-0.2-0.20.7-1.10.2-1.01.2-0.3-0.31.2
Delay disc. indifference point, 8s delay0.20.20.60.8-0.70.20.00.20.1-0.20.7-0.10.4-0.70.00.0-0.8
Delay discount exponential model param0.10.10.1-0.2-0.3-0.20.0-0.2-0.0-0.10.4-0.40.2-0.3-0.1-0.1-0.3
Delay discount hyperbolic model param0.10.10.2-0.3-0.3-0.4-0.2-0.4-0.30.10.4-0.50.1-0.3-0.3-0.3-0.4
Fecal boli incidents, locomotor time 10.80.92.01.3-1.40.60.20.60.3-0.91.20.81.1-1.40.40.5-1.4
Change in fecal boli incidents, locomotor task1.01.02.5-1.11.5-0.4-0.2-0.4-0.20.8-1.5-0.3-1.21.6-0.3-0.41.5
Time >=10cm from walls, locomotor time 10.90.91.90.30.41.11.21.11.3-0.7-1.01.40.30.61.11.10.8
Bouts of movement, locomotor time 10.30.41.0-0.60.3-0.7-0.7-0.7-0.70.70.1-1.0-0.40.1-0.7-0.70.1
Total resting periods, locomotor time 10.80.91.4-1.00.7-1.1-1.2-1.1-1.21.2-0.1-1.0-0.90.5-1.1-1.10.4
Rest time, locomotor task time 10.40.40.6-0.60.8-0.6-0.5-0.6-0.60.8-0.5-0.3-0.80.7-0.6-0.60.6
Distance moved, locomotor task time 10.70.81.60.10.41.11.11.11.3-0.8-1.00.90.30.61.11.10.7
Vertical activity count, locomotor time 10.91.01.80.8-1.01.01.21.01.3-1.30.40.41.1-0.81.21.1-0.7
Time >=10cm from walls, locomotor time 21.11.21.81.2-1.21.10.91.10.9-1.20.71.31.3-1.11.01.0-0.9
Bouts of movement, locomotor time 20.60.61.6-0.81.2-0.3-0.4-0.3-0.30.6-1.2-0.1-1.01.2-0.2-0.21.2
Total resting periods, locomotor time 20.60.71.9-0.81.3-0.2-0.3-0.2-0.20.5-1.40.1-1.01.4-0.1-0.11.4
Rest time, locomotor task time 20.20.30.9-0.40.90.00.10.0-0.00.2-1.00.1-0.51.00.00.10.9
Distance moved, locomotor task time 20.30.30.90.4-0.9-0.1-0.1-0.1-0.0-0.31.0-0.50.5-1.0-0.0-0.1-0.9
Vertical activity count, locomotor time 21.41.53.31.5-1.80.70.70.70.7-1.31.50.21.5-1.80.90.8-1.7
Weight adjusted by age0.10.20.50.3-0.6-0.1-0.0-0.1-0.0-0.10.7-0.20.4-0.7-0.2-0.1-0.7
Seeking ratio, delayed vs. immediate footshock1.11.22.9-1.71.4-0.8-0.6-0.8-0.71.2-1.0-0.5-1.51.4-0.8-0.91.3
Locomotion in novel chamber0.20.30.50.4-0.40.70.60.70.7-0.60.10.30.7-0.40.60.7-0.2
Locomotion in novel chamber post-restriction2.73.24.8-2.01.4-2.2-1.9-2.2-1.92.2-0.3-2.0-1.91.0-2.1-2.00.9
Progressive ratio1.11.22.41.1-1.11.11.01.11.0-1.30.61.51.2-0.91.21.1-0.9
Food seeking constrained by brief footshock1.51.94.7-1.10.9-1.7-1.2-1.7-1.21.6-0.1-2.2-1.40.6-1.7-1.60.5
Seeking ratio, punishment vs. effort2.12.56.0-1.41.2-1.9-1.5-1.9-1.51.9-0.3-2.4-1.60.9-1.9-1.70.8
Run reversals in cocaine runway, females1.51.52.4-1.51.4-1.3-0.7-1.3-0.71.5-0.7-1.6-1.31.2-1.3-1.31.1
Run reversals in cocaine runway, males2.01.93.8-1.91.6-1.3-1.3-1.3-1.31.6-0.9-1.0-1.71.4-1.3-1.11.3
Latency to leave start box in cocaine runway0.80.92.5-0.21.10.70.50.70.5-0.2-1.61.3-0.51.40.80.61.4
Latency to leave start box in cocaine runway, F1.51.64.8-0.41.61.00.91.00.9-0.2-2.21.5-0.61.91.01.02.0
Latency to leave start box in cocaine runway, M0.30.31.10.5-0.9-0.2-0.4-0.2-0.4-0.21.0-0.10.4-0.9-0.1-0.5-1.0
Cd content in liver0.30.30.70.7-0.40.60.70.60.9-0.60.10.20.7-0.40.40.7-0.2
Co content in liver0.91.02.0-0.80.1-1.4-1.2-1.4-1.31.20.6-0.7-0.7-0.1-1.4-1.3-0.3
Cu content in liver1.41.63.20.30.41.51.81.51.7-1.2-1.31.60.60.71.51.60.9
Fe content in liver0.50.61.00.9-1.00.60.60.60.6-0.80.70.60.9-1.00.60.7-0.9
K content in liver0.70.71.7-0.91.2-0.4-0.5-0.4-0.40.7-1.1-0.5-1.11.2-0.3-0.41.3
Mg content in liver0.70.82.3-0.81.4-0.1-0.2-0.1-0.30.6-1.4-0.4-1.01.4-0.2-0.21.5
Mn content in liver2.02.37.7-1.42.50.20.10.20.10.7-2.8-0.1-1.42.60.20.12.8
Na content in liver0.20.20.60.20.50.40.60.40.7-0.2-0.8-0.3-0.10.60.50.40.7
Rb content in liver0.91.12.60.00.51.31.61.31.3-0.9-1.30.90.30.81.31.31.0
Se content in liver0.10.10.2-0.20.3-0.0-0.1-0.0-0.20.2-0.30.4-0.30.3-0.2-0.20.3
Sr content in liver0.60.51.8-0.1-0.9-0.6-0.7-0.6-0.70.31.3-0.30.2-1.0-0.5-0.5-1.2
Zn content in liver2.32.64.5-0.6-0.6-2.0-2.0-2.0-1.81.41.8-2.1-0.7-1.0-2.0-1.9-1.3