RGD1304694

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000031269 0.09 0.05 1.6e-05 0.03 0.04 0.05 0.05 9.2e-05 1.2e-05 1.3e-06 5.7e-06
2 Adipose mRNA stability ENSRNOG00000031269 0.04 0.03 1.2e-03 0.02 0.02 0.01 0.01 9.8e-04 8.9e-04 3.6e-02 1.1e-02
3 BLA mRNA stability ENSRNOG00000031269 0.16 0.1 8.9e-04 0.06 0.05 0.05 0.06 2.2e-04 1.1e-03 9.0e-04 5.7e-04
4 Brain gene expression ENSRNOG00000031269 0.11 0.06 1.3e-12 0.14 0.02 0.13 0.08 2.5e-13 1.1e-02 3.1e-12 3.1e-08
5 Brain mRNA stability ENSRNOG00000031269 0.1 0.05 1.6e-07 0.08 0.06 0.09 0.09 9.4e-08 5.9e-06 2.1e-08 1.9e-08
6 LHb mRNA stability ENSRNOG00000031269 0.17 0.11 8.7e-03 0.08 0.07 0.05 0.09 7.2e-03 1.2e-02 2.7e-02 3.3e-03
7 Liver gene expression ENSRNOG00000031269 0.14 0.07 0.0e+00 0.06 0.05 0.1 0.02 1.7e-07 3.1e-06 7.0e-11 2.4e-03
8 NAcc gene expression ENSRNOG00000031269 0.09 0.07 1.5e-05 0.09 0.06 0.06 0.08 6.5e-07 3.3e-05 1.3e-05 2.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail2.06.48.8-1.30.62.93.02.82.8-2.63.0
BMI without tail1.12.24.80.51.70.81.90.90.8-2.21.9
Body weight0.73.06.90.51.81.02.31.01.1-2.62.3
Epididymis fat weight0.10.20.4-0.10.40.60.20.50.7-0.50.2
Glucose0.91.44.8-0.8-2.0-0.3-1.0-0.3-0.32.2-1.0
Heart weight0.20.30.9-0.9-0.70.4-0.20.30.40.4-0.2
Left kidney weight8.424.043.1-0.14.24.06.44.24.1-6.66.4
Right kidney weight8.423.940.4-0.73.74.36.34.54.3-6.46.3
Tail length0.31.01.81.21.0-1.3-0.6-1.3-1.20.0-0.6
Length with tail0.20.71.61.11.3-1.00.2-0.8-0.7-0.70.2
Length without tail0.20.40.9-0.6-0.20.80.50.81.0-0.50.5
Liver weight, left1.01.73.3-1.4-0.91.70.81.81.8-0.10.8
Liver weight, right0.20.41.61.20.70.00.80.00.1-0.40.8
Parametrial fat weight0.10.20.6-0.2-0.4-0.0-0.5-0.1-0.00.8-0.5
Retroperitoneal fat weight0.92.85.60.31.31.32.41.51.4-2.02.4
Intraocular pressure0.20.20.40.60.6-0.40.6-0.2-0.5-0.20.6
Extensor digitorum longus weight0.21.02.70.61.40.01.20.30.1-1.71.2
Soleus weight0.51.53.1-1.1-0.91.70.61.71.7-0.20.6
Tibialis anterior weight0.00.00.2-0.5-0.10.10.00.30.10.10.0
Tibia length0.00.10.3-0.40.40.20.30.20.3-0.50.3
Number of licking bursts1.01.12.40.50.2-1.5-0.9-1.4-1.50.7-0.9
Food consumed during 24 hour testing period1.82.25.0-0.60.51.32.21.31.3-1.52.2
Times rat made contact with spout0.70.81.6-0.6-0.21.30.81.21.2-0.40.8
Mean time between licks in bursts1.72.43.50.9-0.6-1.9-1.5-1.8-1.91.8-1.5
Mean num. licks in bursts2.73.37.0-0.9-0.32.61.52.52.6-1.11.5
Std. dev. time between licks in bursts0.10.10.3-0.5-0.4-0.0-0.40.10.0-0.0-0.4
Water consumed over 24 hours1.21.42.8-0.41.01.01.60.90.9-1.71.6
Indifference point 0 sec0.40.61.2-0.6-0.1-0.9-1.1-0.8-0.80.3-1.1
Indifference point AUC0.20.20.4-0.6-0.70.4-0.10.40.50.4-0.1
Indifference point function ln k0.91.33.41.31.8-0.31.0-0.3-0.3-1.71.0
Indifference point function log k0.91.33.41.31.8-0.31.0-0.3-0.3-1.71.0
Delay discounting total patch changes 0 sec0.61.01.9-0.5-0.0-1.1-1.4-1.1-1.10.5-1.4
Delay discounting total patch changes 12 sec0.30.30.7-0.8-0.70.60.50.60.70.20.5
Delay discounting total patch changes 18 sec0.91.22.1-1.0-0.9-1.1-1.2-1.0-0.91.5-1.2
Delay discounting total patch changes 24 sec0.30.40.90.40.8-0.9-0.3-0.9-0.8-0.3-0.3
Delay discounting total patch changes 6 sec0.60.92.1-1.5-0.9-0.4-1.3-0.4-0.30.9-1.3
Delay discounting time to switch 0 sec0.20.30.80.4-0.10.10.90.30.10.20.9
Delay discounting water rate 0 sec0.20.31.5-0.31.0-0.2-0.1-0.2-0.2-1.2-0.1
Delay discounting water rate 12 sec1.31.94.01.12.0-1.6-1.0-1.5-1.6-0.9-1.0
Delay discounting water rate 18 sec0.20.20.40.10.4-0.5-0.7-0.5-0.6-0.4-0.7
Delay discounting water rate 24 sec0.30.41.8-0.31.10.4-0.00.40.3-1.3-0.0
Delay discounting water rate 6 sec0.50.71.21.10.5-0.8-0.9-1.0-1.00.1-0.9
Locomotor activity0.71.12.20.61.20.21.50.20.3-1.51.5
Locomotor testing distance0.00.10.20.4-0.0-0.4-0.0-0.4-0.20.2-0.0
Locomotor testing rearing0.20.30.80.90.8-0.50.6-0.5-0.4-0.40.6
Light reinforcement 11.12.05.71.42.4-1.20.7-1.2-1.2-1.70.7
Light reinforcement 21.21.63.81.32.0-0.11.4-0.2-0.2-1.81.4
Reaction time number correct0.40.60.90.60.4-0.9-0.9-0.9-0.9-0.2-0.9
Reaction time mean minus median0.10.10.10.10.3-0.2-0.3-0.3-0.2-0.4-0.3
Reaction time mean minus median AUC0.40.52.00.10.90.50.60.40.4-1.40.6
Reaction time num false alarms0.91.22.41.50.2-1.5-0.4-1.4-1.50.4-0.4
Reaction time num false alarms AUC0.71.02.21.50.4-1.4-0.3-1.3-1.40.3-0.3
Reaction time trials correct on left0.40.60.90.60.4-0.9-0.9-0.9-0.9-0.2-0.9
Reaction time trials on left0.40.60.80.60.3-0.9-0.9-0.9-0.8-0.2-0.9
Reaction time mean0.40.51.3-0.6-1.10.4-0.90.40.30.9-0.9
Reaction time mean AUC0.40.51.1-0.5-1.10.4-0.80.50.30.8-0.8
Median of all reaction times0.91.23.0-1.0-1.70.5-1.10.60.41.4-1.1
Reaction time omissions0.60.92.1-0.7-1.1-0.2-1.4-0.1-0.11.0-1.4
Reaction time false alarm rate0.30.41.11.00.0-0.80.2-0.6-0.80.50.2
Reaction time premature initiation rate2.23.05.7-2.4-0.72.21.22.12.1-0.81.2
Reaction time premature initiations1.11.53.6-1.9-0.51.50.61.41.5-0.80.6
Std. dev. reaction times0.10.10.3-0.0-0.20.2-0.50.20.2-0.0-0.5
Reaction time trials completed0.40.60.80.60.3-0.9-0.9-0.9-0.8-0.2-0.9
Reaction time trials AUC0.30.40.60.50.4-0.7-0.6-0.7-0.7-0.4-0.6
Social response proportion0.20.20.60.20.60.10.70.10.2-0.60.7
Social responses0.70.91.91.31.4-0.30.9-0.5-0.3-1.30.9
Social time1.31.74.4-0.7-1.7-0.4-1.5-0.7-0.42.1-1.5
Conditioned locomotion0.10.20.70.8-0.2-0.50.2-0.4-0.30.30.2
Cocaine response after cond. corrected0.80.91.80.60.5-1.4-0.8-1.2-1.30.5-0.8
Cocaine response after cond. not corrected1.92.14.21.41.0-2.0-0.9-1.9-2.00.3-0.9
Cocaine response before conditioning0.30.41.11.00.2-0.8-0.2-0.7-0.80.2-0.2
Saline control response0.91.12.31.30.7-1.4-0.6-1.5-1.30.3-0.6
Condit. Reinf. active minus inactive responses0.30.40.8-0.9-0.40.50.70.50.6-0.40.7
Condit. Reinf. active-inactive response ratio0.10.10.9-0.9-0.1-0.30.1-0.2-0.2-0.00.1
Condit. Reinf. active responses1.21.72.9-0.70.11.31.71.31.5-1.31.7
Condit. Reinf. inactive responses2.12.64.3-0.10.21.82.11.81.8-1.52.1
Condit. Reinf. lever presses0.70.91.8-0.10.50.71.30.90.9-1.31.3
Condit. Reinf. lever reinforcers received0.81.21.9-0.7-0.11.11.41.21.3-1.01.4
Pavlov. Cond. lever latency0.20.30.70.2-0.4-0.3-0.7-0.4-0.40.8-0.7
Pavlov. Cond. magazine entry latency0.70.82.8-1.7-1.10.3-0.90.60.30.7-0.9
Pavlov. Cond. change in total contacts0.71.02.2-1.5-0.61.00.91.21.1-0.40.9
Pavlov. Cond. index score0.20.20.8-0.9-0.50.50.10.60.5-0.10.1
Pavlov. Cond. latency score0.20.30.9-0.9-0.50.50.20.70.6-0.20.2
Pavlov. Cond. lever contacts0.40.50.7-0.70.10.70.90.80.8-0.80.9
Pavlov. Cond. magazine entry number0.30.31.11.10.6-0.5-0.1-0.7-0.50.0-0.1
Pavlov. Cond. intertrial magazine entries1.11.42.9-1.0-0.71.70.91.61.7-0.40.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.7-0.30.40.10.50.4-0.20.1
Pavlov. Cond. response bias0.30.51.5-1.2-0.40.70.40.80.7-0.30.4
Conditioned reinforcement - actives0.30.30.60.2-0.5-0.3-0.8-0.3-0.20.7-0.8
Conditioned reinforcement - inactives0.10.10.20.10.3-0.20.5-0.0-0.0-0.30.5
Conditioned locomotion0.70.82.60.51.6-0.60.7-0.5-0.4-1.30.7
Intermittent access intake day 1-15 change0.40.40.80.9-0.1-0.6-0.5-0.7-0.70.6-0.5
Intermittent access intake escalation0.50.51.41.20.2-0.7-0.4-0.8-0.80.4-0.4
Intermittent access intake escalation 20.40.41.00.2-0.6-0.4-0.8-0.4-0.51.0-0.8
Intermitt. access day 1 inactive lever presses1.01.11.6-0.90.41.01.31.11.0-1.01.3
Intermitt. access day 15 inactive lever presses1.92.13.6-1.9-0.41.81.31.71.7-0.61.3
Intermitt. access escalation Index0.10.10.6-0.8-0.20.2-0.30.10.10.2-0.3
Intermittent access day 1 total infusions0.50.61.70.20.90.50.80.40.5-1.30.8
Intermittent access day 15 total infusions0.30.41.01.01.0-0.10.3-0.2-0.2-0.90.3
Intermittent access terminal intake (last 3 days)0.30.40.80.70.70.20.70.20.2-0.90.7
Intermittent access total infusions0.50.61.20.80.90.20.90.20.2-1.10.9
Intermittent access day 1 locomotion0.20.20.60.70.8-0.50.2-0.4-0.4-0.50.2
Intermittent access day 15 total locomotion1.31.43.81.62.0-0.70.7-0.6-0.6-1.60.7
Intermittent access total locomotion0.91.12.70.81.50.21.20.30.3-1.71.2
Intermittent access standard deviation0.50.60.9-0.10.11.00.90.90.9-0.60.9
Cocaine induced anxiety3.74.27.1-1.20.42.62.02.72.6-2.02.0
Post-drug Anxiety2.52.85.1-1.7-0.42.11.42.32.1-1.01.4
Baseline Anxiety2.62.85.30.2-1.2-1.7-1.9-1.7-1.72.3-1.9
Lifetime Intake0.80.91.81.01.10.21.20.20.2-1.31.2
Incentive Sensitization - Responses2.72.75.5-1.9-0.12.30.92.22.1-1.20.9
Incentive Sensitization - Breakpoint3.03.06.0-2.0-0.02.41.02.32.3-1.31.0
Progressive ratio test 1 active lever presses0.00.10.10.1-0.10.30.10.30.4-0.20.1
Progressive ratio test 1 breakpoint0.00.00.10.2-0.30.20.10.20.30.00.1
Progressive ratio test 1 inactive lever presses0.20.20.4-0.30.00.40.60.50.4-0.10.6
Progressive ratio test 2 active lever presses1.31.33.0-1.1-0.31.70.51.61.6-0.80.5
Progressive ratio test 2 breakpoint1.41.53.2-1.2-0.21.80.61.71.7-1.00.6
Progressive ratio test 2 inactive lever presses0.91.11.8-0.70.11.31.01.31.3-1.01.0
Total sessions with >9 infusions1.31.44.12.01.5-0.90.9-0.9-0.9-1.10.9
Short access day 1 total inactive lever presses1.31.53.7-0.11.40.31.70.40.3-1.91.7
Short access day 10 total inactive lever presses0.91.01.9-0.81.00.61.40.70.5-1.21.4
Short access day 1 total infusions0.80.81.71.01.0-0.21.3-0.1-0.1-1.11.3
Short access day 10 total infusions0.20.30.80.90.3-0.10.7-0.0-0.0-0.40.7
Short access total infusions1.31.43.31.11.00.31.80.40.3-1.41.8
Short access day 1 locomotion0.10.20.60.80.0-0.50.2-0.5-0.30.20.2
Short access day 10 total locomotion0.40.51.41.2-0.1-0.8-0.1-0.9-0.80.6-0.1
Short access total locomotion0.50.51.41.20.4-0.60.8-0.6-0.5-0.30.8
Compulsive drug intake0.10.10.6-0.80.00.10.10.20.2-0.40.1
One hour access (0.3 mA shock)0.50.61.71.31.1-0.20.6-0.2-0.1-1.10.6
One hour access (shock baseline)0.70.83.92.01.0-0.60.2-0.7-0.6-0.50.2
Number of responses in last shaping day0.50.51.5-0.2-1.2-0.4-0.4-0.3-0.31.2-0.4
Context. condit. distance diff. score1.92.34.10.21.41.12.01.21.1-2.02.0
Locomotion velocity, session 10.50.51.30.01.10.40.80.40.3-1.00.8
Locomotion distance, session 10.20.20.60.40.1-0.6-0.2-0.6-0.80.7-0.2
Locomotion velocity, session 22.02.34.91.02.10.41.90.50.4-2.21.9
Locomotion distance, session 20.20.20.8-0.9-0.60.4-0.10.60.40.3-0.1
Locomotion velocity, session 32.42.85.42.22.3-0.32.0-0.2-0.3-2.12.0
Locomotion distance, session 31.51.65.32.31.3-1.50.3-1.3-1.4-0.50.3
Stereotopy head waving bouts, day 31.51.82.7-0.50.61.51.51.61.4-1.51.5
Stereotopy head waving duration, day 31.92.44.2-0.21.41.22.01.31.1-2.02.0
Locomotion velocity, session 71.51.63.51.61.3-0.21.9-0.1-0.2-1.21.9
Locomotion distance, session 70.10.10.30.60.1-0.20.5-0.1-0.3-0.00.5
Stereotopy head waving bouts, day 72.73.07.71.32.8-0.11.9-0.0-0.1-2.71.9
Stereotopy head waving duration, day 71.11.44.01.02.0-0.31.2-0.3-0.2-1.81.2
Locomotion velocity, session 84.85.812.2-0.22.51.63.21.81.5-3.53.2
Locomotion distance, session 81.21.83.70.41.60.71.71.00.6-1.91.7
Degree of sensitization distance2.32.34.4-2.0-1.02.10.92.01.9-0.20.9
Degree of sensitization stereotypy1.41.64.21.22.0-0.51.3-0.4-0.4-1.81.3
Condit. Reinf. active minus inactive responses0.70.82.2-0.5-1.4-0.1-1.0-0.1-0.11.5-1.0
Condit. Reinf. active-inactive response ratio0.80.82.2-0.5-1.4-0.0-1.1-0.0-0.01.5-1.1
Condit. Reinf. active responses0.81.02.1-0.1-1.1-0.5-1.5-0.5-0.51.4-1.5
Condit. Reinf. inactive responses0.20.30.70.30.0-0.5-0.8-0.4-0.50.2-0.8
Incentive salience index mean0.50.61.50.2-0.9-0.6-0.8-0.6-0.61.2-0.8
Condit. Reinf. lever presses0.40.51.10.90.2-1.0-0.3-0.9-1.00.4-0.3
Time in familiar zone, hab. session 10.50.51.10.30.9-0.11.0-0.0-0.1-0.91.0
Time in novel zone, hab. session 10.20.20.5-0.1-0.5-0.4-0.6-0.4-0.30.7-0.6
Total zone transitions, hab. session 10.81.13.0-0.1-1.2-0.7-1.3-0.6-0.61.7-1.3
Total locomotion distance, hab. session 10.30.41.51.21.0-0.40.1-0.5-0.4-0.50.1
Locomotion velocity, hab. session 10.30.41.41.21.1-0.30.2-0.3-0.3-0.60.2
Time in familiar zone, hab. session 20.40.40.70.50.7-0.7-0.7-0.8-0.80.2-0.7
Time in novel zone, hab. session 20.20.20.4-0.6-0.60.3-0.20.30.40.1-0.2
Total zone transitions, hab. session 20.30.40.9-1.00.10.70.70.70.6-0.40.7
Total locomotion distance, hab. session 20.20.20.80.00.90.10.40.1-0.1-0.90.4
Locomotion velocity, hab. session 20.10.20.5-0.00.70.10.50.20.0-0.70.5
Novel to familiar place preference ratio0.10.10.40.20.50.2-0.30.20.1-0.6-0.3
Novelty place preference0.30.30.90.60.90.1-0.10.0-0.0-0.9-0.1
Time in novel zone, NPP test0.30.31.00.61.0-0.0-0.1-0.0-0.1-1.0-0.1
Total zone transitions, NPP test0.10.20.7-0.3-0.1-0.1-0.9-0.0-0.10.3-0.9
Total locomotion distance, NPP test0.30.51.70.71.3-0.4-0.1-0.4-0.5-1.0-0.1
Locomotion velocity, NPP test0.30.41.10.91.1-0.5-0.2-0.5-0.6-0.6-0.2
Pavlov. Cond. lever latency0.81.01.9-1.10.31.40.41.31.3-0.90.4
Pavlov. Cond. magazine entry latency1.31.74.7-0.3-1.9-0.8-1.3-0.8-0.82.2-1.3
Pavlov. Cond. change in total contacts1.31.43.5-0.5-1.8-0.8-1.1-0.8-0.81.9-1.1
Pavlov. Cond. index score0.71.02.50.1-1.3-0.9-0.8-0.8-0.91.6-0.8
Pavlov. Cond. latency score0.60.81.40.4-0.8-1.1-0.6-1.0-1.01.2-0.6
Pavlov. Cond. lever contacts1.11.32.81.2-0.3-1.7-0.5-1.6-1.51.0-0.5
Pavlov. Cond. magazine entry number1.11.43.70.21.80.71.20.60.7-1.91.2
Pavlov. Cond. intertrial magazine entries0.81.03.4-0.7-0.4-0.2-1.8-0.3-0.30.6-1.8
Pavlov. Cond. lever-magazine prob. diff.1.01.33.20.3-1.3-1.1-0.9-1.1-1.11.8-0.9
Pavlov. Cond. response bias1.41.74.00.3-1.5-1.3-1.2-1.2-1.22.0-1.2
Bone: apparent density0.71.12.0-0.6-0.9-0.8-1.4-0.9-0.81.4-1.4
Bone surface0.20.40.7-0.6-0.7-0.2-0.9-0.3-0.20.8-0.9
Bone volume0.30.40.9-0.3-0.5-0.6-0.8-0.6-0.60.9-0.8
Bone: connectivity density0.30.51.1-0.6-0.5-0.5-1.0-0.7-0.50.8-1.0
Bone: cortical apparent density0.91.22.8-1.4-1.70.7-1.10.40.71.3-1.1
Bone: cortical area0.20.31.10.30.40.11.00.10.1-0.61.0
Bone: cortical porosity0.10.10.3-0.1-0.10.20.50.30.20.10.5
Bone: cortical porosity0.10.10.40.10.20.20.70.20.2-0.10.7
Bone: cortical thickness0.40.61.7-1.1-1.30.5-0.30.20.51.0-0.3
Bone: cortical thickness0.70.81.1-0.7-1.11.10.81.01.10.20.8
Bone: cortical tissue density0.91.12.4-1.4-1.60.9-0.90.50.91.1-0.9
Bone: elastic displacement0.70.83.20.61.8-0.70.2-0.7-0.7-1.20.2
Bone: elastic work1.92.56.10.32.30.32.00.40.3-2.52.0
Bone: endosteal estimation1.83.98.91.32.70.32.50.60.3-3.02.5
Bone: endosteal perimeter2.34.79.82.53.1-0.82.4-0.6-0.8-2.82.4
Bone: final force1.32.13.9-1.7-1.01.90.92.01.9-0.00.9
Bone: final moment1.62.75.0-2.0-1.02.21.02.22.2-0.31.0
Bone: marrow area1.83.99.11.22.70.42.50.60.4-3.02.5
Bone: maximum diameter2.54.59.40.92.50.63.00.70.6-3.13.0
Bone: maximum force1.32.33.9-1.4-0.31.91.52.01.9-0.81.5
Bone: maximum moment1.73.05.0-1.8-0.32.21.62.22.2-1.11.6
Bone: minimum diameter1.52.85.82.42.3-1.31.4-1.2-1.3-1.61.4
Bone: periosteal estimation1.32.65.31.02.00.32.30.50.3-2.32.3
Bone: periosteal perimeter2.03.36.42.02.5-0.82.1-0.7-0.8-2.22.1
Bone: post-yield work1.72.24.5-2.1-2.01.7-0.31.61.71.0-0.3
Bone: stiffness0.91.43.4-1.7-1.81.10.21.21.10.90.2
Bone: tissue strength0.80.83.3-1.8-0.60.7-0.70.70.70.2-0.7
Bone: trabecular number1.11.72.70.5-0.4-1.6-1.4-1.6-1.61.4-1.4
Bone: trabecular spacing2.73.57.50.21.21.32.71.51.3-2.42.7
Bone: trabecular thickness0.20.20.50.2-0.2-0.5-0.5-0.5-0.50.7-0.5
Bone: trabecular tissue density0.50.71.9-1.4-1.20.7-0.30.60.70.7-0.3
Breakpoint value in progressive ratio session0.20.20.5-0.50.10.30.30.60.7-0.50.3
Distance traveled before self-admin0.10.10.2-0.1-0.00.20.40.20.0-0.00.4
Distance traveled after self-admin0.50.51.50.11.1-0.20.8-0.2-0.3-1.20.8
Delta time in closed arm before/after self-admin0.70.72.3-1.5-1.20.60.00.60.60.90.0
Delta time in open arm before/after self-admin1.91.85.21.92.3-1.00.5-1.0-1.1-1.30.5
Diff in mean of infusions in LGA sessions2.02.26.8-1.7-2.61.4-0.11.41.61.3-0.1
Extinction: sum of active levers before priming0.90.93.0-1.7-0.90.9-0.51.01.10.3-0.5
Active lever presses in extinction session 61.71.63.8-1.3-0.81.50.91.71.9-0.60.9
Delta distance traveled before/after self-admin0.91.03.30.91.8-0.50.6-0.5-0.5-1.60.6
Delta ambulatory time before/after self-admin0.50.51.90.41.4-0.50.1-0.5-0.5-1.20.1
Time in closed arm before self-admin0.80.92.2-0.0-0.7-0.5-1.5-0.8-0.71.0-1.5
Time in closed arm after self-admin0.50.51.30.1-0.6-0.7-0.5-0.8-0.71.1-0.5
Time in open arm before self-admin0.10.20.30.60.4-0.20.5-0.1-0.1-0.60.5
Time in open arm after self-admin1.11.23.40.91.80.21.00.30.2-1.91.0
Sum of active levers in priming session hrs 5-60.50.51.0-0.50.10.60.60.81.0-0.80.6
Time to tail flick, vehicle, before self-admin0.30.30.6-0.30.10.8-0.60.60.8-0.4-0.6
Time to tail flick, vehicle, after self-admin0.10.10.20.50.4-0.2-0.3-0.2-0.1-0.3-0.3
Time to tail flick, test, before self-admin0.50.52.31.50.6-0.50.6-0.4-0.3-0.30.6
Time to tail flick, test, after self-admin1.41.42.6-0.8-1.1-0.9-1.6-0.9-0.81.4-1.6
Delta time to tail flick, vehicle, before/after SA0.50.50.7-0.7-0.50.70.80.70.7-0.30.8
Delta time to tail flick, test, before/after SA1.91.73.7-1.7-1.0-0.5-1.9-0.6-0.61.3-1.9
Ambulatory time before self-admin0.10.10.20.10.20.10.50.10.1-0.30.5
Ambulatory time after self-admin0.30.30.8-0.00.9-0.5-0.2-0.6-0.7-0.7-0.2
Total heroin consumption1.21.52.7-0.9-0.11.31.21.31.7-1.31.2
Area under the delay curve1.92.15.1-1.4-2.2-0.0-1.50.20.22.3-1.5
Delay disc. indifference point, 0s delay0.20.20.6-0.4-0.30.8-0.40.50.60.2-0.4
Delay disc. indifference point, 16s delay2.32.36.0-0.9-1.7-0.6-2.0-0.3-0.62.5-2.0
Delay disc. indifference point, 2s delay0.80.92.5-1.2-1.60.4-0.70.40.51.3-0.7
Delay disc. indifference point, 24s delay0.30.20.8-0.9-0.8-0.1-0.10.50.40.3-0.1
Delay disc. indifference point, 4s delay2.22.45.2-2.3-2.10.9-1.30.80.91.9-1.3
Delay disc. indifference point, 8s delay1.11.23.9-0.8-2.00.1-0.90.30.31.7-0.9
Delay discount exponential model param2.02.15.21.52.3-0.01.5-0.3-0.2-2.31.5
Delay discount hyperbolic model param1.81.94.61.52.2-0.11.3-0.3-0.3-2.11.3
Fecal boli incidents, locomotor time 10.40.41.40.10.50.20.70.40.6-1.20.7
Change in fecal boli incidents, locomotor task0.70.71.50.91.0-0.7-0.7-0.9-1.2-0.2-0.7
Time >=10cm from walls, locomotor time 10.70.71.3-0.5-0.00.91.10.90.9-0.71.1
Bouts of movement, locomotor time 10.80.91.9-1.2-1.00.90.61.01.40.10.6
Total resting periods, locomotor time 11.31.52.8-1.7-1.61.10.41.21.70.60.4
Rest time, locomotor task time 10.60.71.2-0.30.10.90.90.91.1-0.90.9
Distance moved, locomotor task time 10.10.10.20.2-0.0-0.10.4-0.2-0.1-0.20.4
Vertical activity count, locomotor time 10.10.10.4-0.2-0.6-0.1-0.2-0.3-0.40.6-0.2
Time >=10cm from walls, locomotor time 20.10.10.20.20.2-0.2-0.3-0.2-0.40.0-0.3
Bouts of movement, locomotor time 21.92.04.2-1.9-2.01.50.11.51.70.90.1
Total resting periods, locomotor time 22.22.44.7-2.1-2.21.70.11.61.90.80.1
Rest time, locomotor task time 20.50.51.8-0.2-0.5-0.1-1.3-0.10.10.6-1.3
Distance moved, locomotor task time 21.41.73.01.21.7-0.01.7-0.1-0.4-1.71.7
Vertical activity count, locomotor time 21.41.52.91.11.70.11.6-0.1-0.5-1.61.6
Weight adjusted by age0.70.81.50.81.10.31.20.50.4-1.21.2
Seeking ratio, delayed vs. immediate footshock0.70.81.40.5-0.4-1.0-1.0-1.2-0.90.6-1.0
Locomotion in novel chamber2.63.26.12.51.7-2.2-1.1-2.2-2.2-0.0-1.1
Locomotion in novel chamber post-restriction0.20.21.01.0-0.1-0.50.3-0.2-0.2-0.10.3
Progressive ratio0.30.31.2-0.6-1.10.4-0.20.30.30.7-0.2
Food seeking constrained by brief footshock0.20.30.80.50.3-0.00.90.10.3-0.60.9
Seeking ratio, punishment vs. effort0.20.20.60.20.60.00.70.10.3-0.80.7
Run reversals in cocaine runway, females2.72.74.31.30.1-2.1-1.8-1.8-1.91.4-1.8
Run reversals in cocaine runway, males0.80.82.01.21.4-0.60.6-0.4-0.5-1.20.6
Latency to leave start box in cocaine runway0.70.81.80.31.10.41.30.30.2-1.01.3
Latency to leave start box in cocaine runway, F0.10.10.20.10.30.30.40.20.2-0.30.4
Latency to leave start box in cocaine runway, M1.11.02.40.10.90.71.50.70.6-1.21.5
Cd content in liver0.40.40.9-0.7-0.70.2-1.00.00.10.7-1.0
Co content in liver0.40.41.10.71.0-0.40.6-0.4-0.4-0.80.6
Cu content in liver3.84.67.60.8-0.9-2.4-2.8-2.2-2.22.1-2.8
Fe content in liver0.10.10.4-0.7-0.0-0.5-0.1-0.3-0.20.2-0.1
K content in liver0.30.30.9-0.90.10.7-0.00.70.8-0.6-0.0
Mg content in liver0.40.41.6-1.3-0.50.4-0.50.50.50.2-0.5
Mn content in liver0.60.61.21.01.10.11.00.10.2-1.01.0
Na content in liver1.01.12.3-0.8-1.4-0.8-1.1-0.6-0.71.5-1.1
Rb content in liver0.60.71.5-1.0-1.00.1-1.20.00.00.9-1.2
Se content in liver0.30.40.60.70.5-0.8-0.7-0.7-0.70.0-0.7
Sr content in liver0.20.20.60.8-0.1-0.5-0.3-0.5-0.50.5-0.3
Zn content in liver1.01.11.91.0-0.0-1.3-1.0-1.3-1.40.9-1.0