Smarcc2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000031135 0.04 0.03 1.4e-04 0.02 0.03 0.02 0.03 1.2e-03 7.1e-04 9.9e-04 8.6e-04
2 BLA gene expression ENSRNOG00000031135 0.08 0.06 6.8e-05 0.08 0.08 0.08 0.08 6.6e-05 5.0e-05 3.3e-05 4.9e-05
3 Brain isoform ratio ENSRNOT00000097786 0.04 0.03 8.0e-03 0.02 0.01 0.01 0.01 5.5e-03 1.6e-02 2.4e-02 1.9e-02
4 Brain intron excision ratio chr7:902231:902576 0.03 0.03 1.8e-03 0.01 0.01 0.01 0.01 2.2e-02 3.9e-02 4.0e-02 6.1e-02
5 Liver gene expression ENSRNOG00000031135 0.1 0.06 4.7e-09 0.07 0.07 0.08 0.08 9.7e-09 1.1e-08 8.8e-09 5.3e-09
6 NAcc isoform ratio ENSRNOT00000097786 0.05 0.03 2.1e-03 0.03 0.02 0.01 0.02 3.7e-03 1.9e-02 8.0e-02 8.1e-03
7 PL gene expression ENSRNOG00000031135 0.03 0.02 1.0e-02 0.02 0.02 0.01 0.02 1.1e-02 9.9e-03 3.9e-02 1.1e-02
8 PL intron excision ratio chr7:902231:902576 0.08 0.08 1.9e-04 0.05 0.05 0.04 0.05 1.6e-04 1.5e-04 5.6e-04 1.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail8.126.427.9-5.3-5.25.15.1-5.25.2-4.95.1
BMI without tail1.53.24.0-1.8-2.01.62.0-1.61.7-1.91.6
Body weight1.35.76.9-2.5-2.42.32.2-2.32.3-2.42.6
Epididymis fat weight0.10.20.40.50.3-0.6-0.20.6-0.60.2-0.4
Glucose1.93.03.3-1.8-1.81.71.5-1.81.7-1.71.7
Heart weight0.00.10.20.0-0.30.10.5-0.2-0.1-0.3-0.2
Left kidney weight0.10.40.8-0.70.00.8-0.1-0.90.80.20.8
Right kidney weight0.20.61.10.70.9-0.5-0.90.4-0.51.1-0.8
Tail length5.015.117.34.13.7-4.1-3.54.2-4.13.3-4.0
Length with tail1.76.47.52.52.6-2.5-2.72.6-2.52.4-2.3
Length without tail0.10.30.7-0.6-0.10.7-0.1-0.70.70.00.8
Liver weight, left1.52.53.4-1.5-1.81.51.8-1.61.5-1.81.2
Liver weight, right1.01.72.1-1.3-1.41.31.3-1.31.5-1.21.0
Parametrial fat weight0.10.10.30.40.1-0.30.10.5-0.40.1-0.4
Retroperitoneal fat weight2.58.39.7-2.9-3.12.83.0-2.72.7-3.02.7
Intraocular pressure0.50.71.40.90.5-1.2-0.31.1-1.10.1-0.9
Extensor digitorum longus weight5.622.527.0-4.7-5.24.35.1-4.44.4-5.24.5
Soleus weight6.819.722.2-4.6-4.54.34.2-4.44.4-4.44.7
Tibialis anterior weight1.34.75.4-2.3-2.22.12.0-2.22.1-2.12.3
Tibia length1.13.24.41.81.7-1.9-1.62.1-1.91.5-1.7
Number of licking bursts3.44.05.5-1.9-2.31.72.3-1.71.7-2.32.0
Food consumed during 24 hour testing period0.50.50.7-0.8-0.80.70.6-0.70.8-0.70.8
Times rat made contact with spout1.11.21.9-1.0-1.40.91.2-0.91.0-1.31.0
Mean time between licks in bursts0.91.32.11.30.9-1.1-0.71.1-1.20.9-1.5
Mean num. licks in bursts0.81.01.60.91.0-0.9-1.20.9-0.81.1-1.0
Std. dev. time between licks in bursts0.50.61.30.61.0-0.3-1.10.3-0.31.2-0.7
Water consumed over 24 hours0.91.11.8-1.2-0.81.30.5-1.31.3-0.51.1
Indifference point 0 sec3.96.47.7-2.6-2.52.82.1-2.82.8-2.22.3
Indifference point AUC0.60.70.90.90.8-0.9-0.70.8-0.90.8-0.7
Indifference point function ln k0.20.20.3-0.4-0.50.60.4-0.60.6-0.50.0
Indifference point function log k0.20.20.3-0.4-0.50.60.4-0.60.6-0.50.0
Delay discounting total patch changes 0 sec3.65.97.3-2.5-2.52.62.1-2.72.6-2.22.2
Delay discounting total patch changes 12 sec1.72.33.1-1.4-1.81.41.7-1.41.3-1.71.3
Delay discounting total patch changes 18 sec0.00.00.1-0.2-0.20.10.2-0.30.1-0.20.2
Delay discounting total patch changes 24 sec0.60.71.0-1.0-0.70.90.6-1.00.9-0.71.0
Delay discounting total patch changes 6 sec2.13.23.7-1.8-1.81.91.6-1.91.9-1.61.6
Delay discounting time to switch 0 sec0.30.41.4-0.8-0.30.70.3-0.60.7-0.31.2
Delay discounting water rate 0 sec0.50.71.5-0.7-1.10.71.1-0.80.6-1.20.2
Delay discounting water rate 12 sec0.81.12.2-0.9-1.40.81.5-0.90.8-1.40.4
Delay discounting water rate 18 sec0.30.40.90.4-0.6-0.50.70.7-0.5-0.9-0.9
Delay discounting water rate 24 sec1.31.84.9-0.8-1.90.52.1-0.50.5-2.20.4
Delay discounting water rate 6 sec0.60.82.71.00.2-0.9-0.11.0-1.00.1-1.6
Locomotor activity3.45.49.12.22.5-2.1-3.02.2-1.92.6-1.9
Locomotor testing distance1.32.13.61.41.5-1.3-1.91.3-1.21.6-1.3
Locomotor testing rearing0.00.00.10.1-0.1-0.3-0.00.2-0.1-0.2-0.0
Light reinforcement 13.66.78.12.62.7-2.4-2.72.3-2.42.6-2.9
Light reinforcement 21.11.41.91.21.2-1.1-1.11.2-1.11.2-1.4
Reaction time number correct0.81.22.3-1.0-1.30.71.4-0.80.8-1.50.9
Reaction time mean minus median1.62.02.61.41.5-1.3-1.61.6-1.31.4-1.2
Reaction time mean minus median AUC1.62.04.31.11.9-0.9-2.11.1-1.01.9-0.6
Reaction time num false alarms0.60.81.1-0.9-1.00.80.9-0.80.8-1.00.8
Reaction time num false alarms AUC0.70.91.6-0.9-1.20.81.1-0.80.8-1.20.8
Reaction time trials correct on left0.81.22.3-1.0-1.30.71.4-0.80.8-1.50.9
Reaction time trials on left0.81.12.1-1.0-1.30.71.3-0.80.8-1.51.0
Reaction time mean1.11.52.61.11.6-1.0-1.41.0-1.11.6-0.7
Reaction time mean AUC0.50.61.40.71.1-0.5-1.00.5-0.61.2-0.3
Median of all reaction times0.50.71.40.71.1-0.7-0.90.5-0.81.2-0.4
Reaction time omissions0.00.00.1-0.10.10.2-0.0-0.30.10.2-0.0
Reaction time false alarm rate0.10.20.2-0.5-0.40.50.2-0.40.4-0.30.4
Reaction time premature initiation rate1.52.13.21.61.1-1.8-0.91.7-1.60.9-1.6
Reaction time premature initiations0.71.01.91.10.3-1.4-0.21.3-1.20.0-1.2
Std. dev. reaction times0.81.11.81.01.3-0.9-1.30.9-0.91.3-0.7
Reaction time trials completed0.81.12.1-1.0-1.30.71.3-0.80.8-1.51.0
Reaction time trials AUC0.91.32.6-1.0-1.40.71.5-0.70.8-1.61.0
Social response proportion0.90.91.40.91.2-1.0-1.10.9-0.81.1-0.6
Social responses9.111.814.13.43.8-3.3-3.73.4-3.23.7-3.0
Social time1.11.51.9-1.3-1.31.11.2-1.01.1-1.41.3
Conditioned locomotion0.91.12.5-0.9-1.30.51.5-0.50.6-1.60.8
Cocaine response after cond. corrected2.32.65.3-1.4-1.91.22.3-1.21.2-2.01.3
Cocaine response after cond. not corrected2.42.65.6-1.4-2.01.22.4-1.21.2-2.11.1
Cocaine response before conditioning0.50.60.90.80.8-0.7-1.00.7-0.60.9-0.9
Saline control response0.40.50.7-0.7-0.80.60.8-0.60.7-0.90.8
Condit. Reinf. active minus inactive responses2.22.84.71.91.3-1.8-1.01.8-1.81.2-2.2
Condit. Reinf. active-inactive response ratio0.90.91.71.00.3-1.20.11.2-1.20.1-1.3
Condit. Reinf. active responses1.42.03.11.61.3-1.4-1.21.4-1.31.3-1.8
Condit. Reinf. inactive responses0.30.40.80.50.8-0.3-0.90.4-0.30.9-0.5
Condit. Reinf. lever presses2.94.15.52.21.8-2.2-1.62.2-2.11.6-2.3
Condit. Reinf. lever reinforcers received1.11.52.61.41.1-1.3-0.91.3-1.21.0-1.6
Pavlov. Cond. lever latency1.72.32.8-1.5-1.61.51.7-1.61.4-1.51.4
Pavlov. Cond. magazine entry latency2.52.93.21.71.8-1.6-1.81.7-1.71.7-1.6
Pavlov. Cond. change in total contacts0.81.11.51.11.0-1.0-1.11.1-0.90.9-1.2
Pavlov. Cond. index score2.22.93.21.81.7-1.7-1.71.7-1.61.6-1.7
Pavlov. Cond. latency score2.33.03.61.71.8-1.7-1.91.7-1.61.7-1.6
Pavlov. Cond. lever contacts1.52.02.41.51.4-1.5-1.41.5-1.41.2-1.5
Pavlov. Cond. magazine entry number2.32.83.1-1.7-1.71.51.8-1.61.6-1.71.6
Pavlov. Cond. intertrial magazine entries0.91.21.8-1.0-1.30.91.2-0.91.0-1.30.9
Pavlov. Cond. lever-magazine prob. diff.2.33.03.31.81.7-1.6-1.81.7-1.61.7-1.8
Pavlov. Cond. response bias2.33.23.61.91.7-1.8-1.61.9-1.81.6-1.9
Conditioned reinforcement - actives0.10.10.30.10.10.3-0.2-0.30.30.4-0.5
Conditioned reinforcement - inactives1.21.42.6-0.9-1.61.01.6-1.01.0-1.4-0.0
Conditioned locomotion2.73.36.91.91.6-1.5-1.61.5-1.51.9-2.6
Intermittent access intake day 1-15 change0.40.42.00.70.3-0.4-0.20.4-0.40.4-1.4
Intermittent access intake escalation0.50.42.10.6-0.2-0.50.40.5-0.5-0.2-1.4
Intermittent access intake escalation 20.90.92.81.10.3-1.0-0.11.0-1.00.3-1.7
Intermitt. access day 1 inactive lever presses0.30.41.50.5-0.3-0.50.50.5-0.5-0.3-1.2
Intermitt. access day 15 inactive lever presses1.01.12.81.20.6-1.2-0.51.2-1.20.5-1.7
Intermitt. access escalation Index0.20.20.50.00.40.4-0.7-0.40.40.7-0.2
Intermittent access day 1 total infusions0.40.40.6-0.7-0.60.80.4-0.80.8-0.50.7
Intermittent access day 15 total infusions0.20.20.4-0.3-0.60.40.6-0.40.4-0.5-0.3
Intermittent access terminal intake (last 3 days)0.20.30.6-0.4-0.40.80.3-0.80.8-0.2-0.0
Intermittent access total infusions0.40.50.6-0.6-0.80.80.7-0.80.8-0.60.3
Intermittent access day 1 locomotion0.00.00.0-0.0-0.1-0.00.10.0-0.0-0.1-0.0
Intermittent access day 15 total locomotion0.50.62.30.80.4-0.5-0.30.5-0.50.5-1.5
Intermittent access total locomotion0.20.30.60.50.5-0.4-0.50.4-0.40.6-0.7
Intermittent access standard deviation0.20.31.40.50.1-0.3-0.10.3-0.30.2-1.2
Cocaine induced anxiety1.51.72.91.11.7-1.1-1.71.1-1.11.7-0.8
Post-drug Anxiety0.50.51.60.21.0-0.1-1.30.1-0.11.20.2
Baseline Anxiety0.00.00.1-0.0-0.20.00.2-0.00.0-0.3-0.1
Lifetime Intake1.21.32.0-1.1-1.11.40.9-1.41.4-0.80.7
Incentive Sensitization - Responses0.10.10.40.40.2-0.2-0.20.2-0.20.3-0.6
Incentive Sensitization - Breakpoint0.20.20.50.40.4-0.2-0.40.2-0.20.5-0.7
Progressive ratio test 1 active lever presses1.51.51.8-1.2-1.31.31.2-1.31.3-1.20.9
Progressive ratio test 1 breakpoint1.61.72.0-1.3-1.31.41.2-1.41.4-1.21.0
Progressive ratio test 1 inactive lever presses0.10.20.80.1-0.20.4-0.0-0.40.40.2-0.9
Progressive ratio test 2 active lever presses0.60.60.9-0.7-0.81.00.7-1.01.0-0.60.3
Progressive ratio test 2 breakpoint0.20.20.6-0.4-0.30.80.1-0.80.8-0.10.1
Progressive ratio test 2 inactive lever presses0.30.40.8-0.5-0.50.90.3-0.90.9-0.20.1
Total sessions with >9 infusions0.60.71.6-0.6-0.31.3-0.0-1.31.30.20.2
Short access day 1 total inactive lever presses0.10.10.2-0.0-0.20.30.1-0.30.30.0-0.4
Short access day 10 total inactive lever presses0.20.20.90.2-0.4-0.10.50.1-0.1-0.3-0.9
Short access day 1 total infusions1.41.43.1-1.1-0.71.80.3-1.81.8-0.20.6
Short access day 10 total infusions0.91.01.4-0.9-1.01.20.8-1.21.2-0.70.5
Short access total infusions2.12.34.2-1.5-1.22.00.8-2.02.0-0.81.1
Short access day 1 locomotion0.10.10.30.20.20.2-0.4-0.20.20.5-0.5
Short access day 10 total locomotion2.02.15.81.61.0-1.4-0.71.4-1.41.1-2.4
Short access total locomotion0.20.20.70.50.4-0.2-0.50.2-0.20.6-0.9
Compulsive drug intake0.30.30.5-0.6-0.40.50.4-0.50.5-0.40.7
One hour access (0.3 mA shock)0.40.50.6-0.7-0.70.80.8-0.80.8-0.60.5
One hour access (shock baseline)0.10.20.3-0.1-0.60.20.6-0.20.2-0.5-0.4
Number of responses in last shaping day1.01.13.01.10.8-0.7-0.80.8-0.81.0-1.7
Context. condit. distance diff. score0.20.30.3-0.5-0.50.50.5-0.50.5-0.60.4
Locomotion velocity, session 10.30.30.7-0.60.10.5-0.4-0.60.60.30.9
Locomotion distance, session 10.30.41.20.10.80.1-1.1-0.10.11.00.2
Locomotion velocity, session 21.21.43.20.81.5-0.5-1.80.5-0.61.8-0.7
Locomotion distance, session 22.53.56.81.62.4-1.4-2.61.4-1.52.5-1.0
Locomotion velocity, session 35.26.06.52.52.5-2.5-2.42.5-2.52.3-2.3
Locomotion distance, session 30.10.10.20.30.2-0.4-0.30.3-0.40.1-0.2
Stereotopy head waving bouts, day 35.87.07.92.72.8-2.5-2.72.5-2.52.8-2.6
Stereotopy head waving duration, day 33.84.65.82.22.2-1.9-2.12.0-1.92.3-2.4
Locomotion velocity, session 70.10.10.20.20.4-0.1-0.40.0-0.10.5-0.2
Locomotion distance, session 70.10.10.4-0.1-0.40.10.6-0.0-0.0-0.5-0.0
Stereotopy head waving bouts, day 70.80.92.00.71.3-0.7-1.40.6-0.61.3-0.4
Stereotopy head waving duration, day 70.70.82.10.51.3-0.6-1.50.5-0.51.3-0.2
Locomotion velocity, session 81.31.54.00.81.6-0.8-2.00.7-0.71.8-0.3
Locomotion distance, session 80.30.51.00.60.9-0.6-1.00.6-0.60.9-0.3
Degree of sensitization distance0.60.60.7-0.8-0.80.80.8-0.80.8-0.70.7
Degree of sensitization stereotypy0.20.20.7-0.50.00.4-0.2-0.40.50.10.8
Condit. Reinf. active minus inactive responses2.02.32.61.61.6-1.4-1.61.3-1.51.6-1.5
Condit. Reinf. active-inactive response ratio0.30.30.70.70.3-0.6-0.30.6-0.60.3-0.9
Condit. Reinf. active responses2.83.54.81.82.1-1.5-2.21.5-1.62.2-1.7
Condit. Reinf. inactive responses1.51.73.01.11.7-1.0-1.71.0-1.01.7-0.9
Incentive salience index mean1.31.52.61.11.5-0.9-1.60.9-1.01.5-0.9
Condit. Reinf. lever presses0.40.51.60.11.0-0.0-1.30.0-0.11.20.4
Time in familiar zone, hab. session 15.65.36.42.42.2-2.5-2.02.5-2.51.9-2.3
Time in novel zone, hab. session 14.14.05.5-2.2-1.62.31.4-2.32.3-1.32.2
Total zone transitions, hab. session 10.50.71.80.51.1-0.4-1.30.4-0.41.2-0.1
Total locomotion distance, hab. session 11.62.45.51.12.0-0.9-2.30.8-0.92.3-0.8
Locomotion velocity, hab. session 11.82.55.11.32.0-1.1-2.31.0-1.12.2-1.1
Time in familiar zone, hab. session 25.35.57.02.62.0-2.6-1.82.6-2.61.8-2.6
Time in novel zone, hab. session 25.95.97.6-2.7-2.12.71.8-2.72.8-1.82.7
Total zone transitions, hab. session 20.70.91.6-1.1-0.21.2-0.2-1.21.20.01.2
Total locomotion distance, hab. session 20.40.51.50.31.0-0.3-1.20.3-0.31.0-0.1
Locomotion velocity, hab. session 20.50.61.90.31.1-0.3-1.40.3-0.31.2-0.0
Novel to familiar place preference ratio3.13.34.9-2.0-1.32.10.8-2.22.1-1.12.2
Novelty place preference2.12.23.5-1.6-1.01.70.5-1.91.7-0.81.8
Time in novel zone, NPP test2.72.94.4-1.9-1.32.00.8-2.12.0-1.01.9
Total zone transitions, NPP test0.30.51.3-0.9-0.30.8-0.0-0.70.8-0.21.1
Total locomotion distance, NPP test0.20.20.6-0.40.20.5-0.5-0.50.40.30.8
Locomotion velocity, NPP test0.10.20.6-0.10.60.1-0.8-0.10.10.60.4
Pavlov. Cond. lever latency0.10.20.50.0-0.6-0.10.60.2-0.1-0.7-0.2
Pavlov. Cond. magazine entry latency1.62.12.61.61.4-1.5-1.11.4-1.61.3-1.5
Pavlov. Cond. change in total contacts0.20.20.5-0.4-0.30.60.3-0.70.4-0.30.4
Pavlov. Cond. index score0.40.51.00.61.0-0.5-1.00.4-0.61.0-0.5
Pavlov. Cond. latency score0.50.61.40.61.1-0.4-1.10.4-0.51.2-0.4
Pavlov. Cond. lever contacts0.20.20.5-0.20.50.3-0.7-0.40.20.70.5
Pavlov. Cond. magazine entry number0.50.70.9-0.9-0.90.80.7-0.70.9-0.80.8
Pavlov. Cond. intertrial magazine entries0.10.10.40.4-0.0-0.4-0.00.4-0.4-0.2-0.6
Pavlov. Cond. lever-magazine prob. diff.0.60.71.20.81.1-0.6-1.10.5-0.71.1-0.6
Pavlov. Cond. response bias0.80.91.21.01.1-0.9-1.00.8-1.01.0-0.9
Bone: apparent density0.40.71.0-0.50.50.8-1.0-0.80.91.00.8
Bone surface0.81.33.5-0.21.20.9-1.9-0.80.91.80.5
Bone volume0.81.32.7-0.40.91.1-1.6-1.11.21.60.8
Bone: connectivity density0.20.30.7-0.30.40.6-0.8-0.50.60.80.4
Bone: cortical apparent density1.52.02.3-1.4-1.51.51.5-1.41.5-1.41.2
Bone: cortical area1.21.83.1-1.4-0.81.80.5-1.71.8-0.41.4
Bone: cortical porosity0.10.10.20.10.20.2-0.4-0.30.20.4-0.2
Bone: cortical porosity0.20.30.6-0.4-0.10.8-0.2-0.80.70.20.3
Bone: cortical thickness1.62.63.7-1.7-1.41.91.2-1.81.9-1.21.6
Bone: cortical thickness0.80.91.4-1.0-1.10.91.0-0.80.9-1.20.9
Bone: cortical tissue density1.11.41.6-1.2-1.21.31.3-1.21.2-1.21.0
Bone: elastic displacement0.00.00.00.00.00.10.0-0.00.00.1-0.1
Bone: elastic work0.70.91.6-1.1-0.71.10.6-1.01.1-0.61.2
Bone: endosteal estimation0.81.62.5-1.3-1.01.60.9-1.61.6-0.71.2
Bone: endosteal perimeter0.20.41.20.40.7-0.1-1.0-0.1-0.11.1-0.4
Bone: final force2.94.86.7-2.4-1.82.51.4-2.52.6-1.52.5
Bone: final moment2.84.66.4-2.4-1.82.51.3-2.42.5-1.42.4
Bone: marrow area0.71.42.2-1.2-1.01.50.9-1.51.5-0.71.1
Bone: maximum diameter0.30.51.60.40.90.0-1.10.00.01.3-0.4
Bone: maximum force3.15.57.3-2.5-2.02.71.7-2.62.7-1.72.6
Bone: maximum moment3.15.37.2-2.5-2.02.61.6-2.52.7-1.72.5
Bone: minimum diameter0.30.61.3-0.8-0.41.10.2-1.11.1-0.10.8
Bone: periosteal estimation1.32.64.4-1.7-1.02.10.8-2.12.1-0.61.7
Bone: periosteal perimeter0.20.30.6-0.30.20.7-0.5-0.80.70.60.4
Bone: post-yield work0.40.60.6-0.8-0.80.80.7-0.80.8-0.70.7
Bone: stiffness4.97.89.7-3.0-2.63.12.2-3.03.1-2.32.9
Bone: tissue strength4.74.65.4-2.2-2.02.31.9-2.32.3-1.82.1
Bone: trabecular number0.71.02.80.71.4-0.5-1.70.5-0.41.6-0.3
Bone: trabecular spacing0.50.72.20.0-1.1-0.31.50.2-0.3-1.4-0.4
Bone: trabecular thickness1.11.32.0-0.80.61.3-1.3-1.31.41.11.2
Bone: trabecular tissue density6.18.510.3-2.8-3.22.73.2-2.82.8-3.22.6
Breakpoint value in progressive ratio session2.32.63.51.71.4-1.7-1.31.7-1.71.3-1.9
Distance traveled before self-admin1.01.11.81.01.1-0.9-1.31.0-0.91.1-0.9
Distance traveled after self-admin0.20.20.60.40.5-0.3-0.80.4-0.30.6-0.5
Delta time in closed arm before/after self-admin1.01.02.9-0.4-1.40.31.7-0.30.3-1.6-0.1
Delta time in open arm before/after self-admin1.51.43.1-1.4-1.01.20.7-1.11.2-1.01.8
Diff in mean of infusions in LGA sessions2.32.53.61.71.5-1.6-1.31.6-1.61.5-1.9
Extinction: sum of active levers before priming3.53.55.12.01.5-2.3-1.22.2-2.31.2-1.9
Active lever presses in extinction session 61.31.31.71.11.3-1.1-1.31.1-1.11.2-0.7
Delta distance traveled before/after self-admin0.00.00.1-0.2-0.20.30.1-0.20.3-0.10.1
Delta ambulatory time before/after self-admin0.10.10.2-0.3-0.10.40.0-0.40.40.10.3
Time in closed arm before self-admin0.30.30.9-0.60.00.7-0.2-0.70.70.11.0
Time in closed arm after self-admin0.30.30.5-0.5-0.60.70.6-0.70.7-0.50.1
Time in open arm before self-admin0.40.52.00.80.2-0.5-0.10.6-0.50.4-1.4
Time in open arm after self-admin1.01.11.6-1.1-1.20.91.2-0.90.9-1.21.1
Sum of active levers in priming session hrs 5-60.40.40.40.60.6-0.6-0.60.7-0.60.5-0.6
Time to tail flick, vehicle, before self-admin1.51.53.51.01.5-0.6-1.70.5-0.61.9-1.2
Time to tail flick, vehicle, after self-admin0.40.40.70.70.3-0.8-0.20.8-0.80.1-0.7
Time to tail flick, test, before self-admin0.80.81.90.81.2-0.6-1.20.5-0.61.4-0.6
Time to tail flick, test, after self-admin0.10.10.50.10.50.1-0.7-0.10.10.70.1
Delta time to tail flick, vehicle, before/after SA1.01.02.5-0.7-1.20.21.4-0.20.2-1.61.0
Delta time to tail flick, test, before/after SA0.20.10.30.30.1-0.50.00.6-0.5-0.1-0.3
Ambulatory time before self-admin0.30.30.60.50.6-0.5-0.80.5-0.50.6-0.5
Ambulatory time after self-admin0.00.10.20.20.2-0.0-0.40.2-0.00.3-0.2
Total heroin consumption2.42.93.61.71.9-1.7-1.81.7-1.71.8-1.4
Area under the delay curve0.10.10.4-0.30.10.0-0.2-0.20.20.00.6
Delay disc. indifference point, 0s delay1.71.84.4-1.6-0.71.50.3-1.61.6-0.52.1
Delay disc. indifference point, 16s delay0.30.30.40.40.6-0.6-0.50.5-0.50.5-0.4
Delay disc. indifference point, 2s delay0.30.31.1-0.7-0.20.50.0-0.60.6-0.11.0
Delay disc. indifference point, 24s delay0.30.30.8-0.7-0.40.30.3-0.40.4-0.50.9
Delay disc. indifference point, 4s delay0.40.40.90.40.9-0.4-1.00.3-0.30.9-0.0
Delay disc. indifference point, 8s delay0.10.10.3-0.2-0.4-0.10.4-0.00.0-0.60.4
Delay discount exponential model param0.00.00.30.2-0.10.10.20.1-0.1-0.0-0.5
Delay discount hyperbolic model param0.10.10.50.40.1-0.10.10.3-0.30.1-0.7
Fecal boli incidents, locomotor time 10.60.71.5-0.7-1.00.41.2-0.50.4-1.20.8
Change in fecal boli incidents, locomotor task0.60.51.50.41.0-0.1-1.20.3-0.31.1-0.3
Time >=10cm from walls, locomotor time 10.70.71.1-1.0-0.51.00.3-1.11.1-0.31.0
Bouts of movement, locomotor time 10.50.50.80.80.7-0.9-0.50.7-0.70.6-0.8
Total resting periods, locomotor time 11.11.31.61.21.1-1.3-1.01.1-1.11.1-1.1
Rest time, locomotor task time 10.50.50.80.60.9-0.7-0.80.6-0.60.8-0.4
Distance moved, locomotor task time 10.80.91.7-1.0-0.61.30.3-1.11.1-0.40.9
Vertical activity count, locomotor time 11.21.31.8-1.1-1.31.31.1-1.11.2-1.20.7
Time >=10cm from walls, locomotor time 21.21.21.8-1.0-1.31.01.4-1.01.0-1.30.9
Bouts of movement, locomotor time 20.30.30.90.30.8-0.4-1.00.2-0.20.9-0.2
Total resting periods, locomotor time 20.30.30.90.30.8-0.3-1.00.1-0.10.9-0.1
Rest time, locomotor task time 20.10.10.3-0.00.5-0.0-0.6-0.00.00.50.2
Distance moved, locomotor task time 20.10.10.3-0.0-0.50.10.50.0-0.0-0.5-0.2
Vertical activity count, locomotor time 21.31.42.7-1.0-1.60.91.5-0.90.9-1.60.8
Weight adjusted by age0.10.10.10.1-0.2-0.20.40.1-0.2-0.3-0.3
Seeking ratio, delayed vs. immediate footshock1.31.42.31.21.3-0.8-1.40.9-0.81.5-1.4
Locomotion in novel chamber0.30.30.5-0.5-0.60.60.7-0.70.6-0.50.2
Locomotion in novel chamber post-restriction3.74.34.72.22.1-2.1-1.92.0-2.12.0-2.1
Progressive ratio1.21.41.9-1.1-1.41.21.3-1.11.2-1.30.9
Food seeking constrained by brief footshock1.82.22.71.51.6-1.7-1.41.6-1.71.3-1.2
Seeking ratio, punishment vs. effort2.53.13.71.81.9-1.9-1.71.7-1.91.7-1.4
Run reversals in cocaine runway, females1.81.82.51.31.5-1.3-1.51.3-1.31.6-1.0
Run reversals in cocaine runway, males2.42.33.31.51.7-1.3-1.61.1-1.31.8-1.6
Latency to leave start box in cocaine runway0.40.40.9-0.60.10.8-0.6-0.60.80.31.0
Latency to leave start box in cocaine runway, F0.70.71.6-0.80.21.0-0.6-1.01.00.41.3
Latency to leave start box in cocaine runway, M0.10.10.20.1-0.4-0.10.20.5-0.1-0.5-0.2
Cd content in liver0.30.40.6-0.6-0.50.60.7-0.70.4-0.60.8
Co content in liver1.31.52.11.41.0-1.3-0.81.3-1.40.9-1.5
Cu content in liver1.21.42.5-1.3-0.91.60.8-1.61.5-0.50.9
Fe content in liver0.50.61.1-0.7-0.90.61.0-0.70.6-0.90.4
K content in liver0.50.51.10.60.9-0.5-1.00.4-0.31.0-0.7
Mg content in liver0.40.41.00.30.9-0.3-1.00.2-0.21.0-0.0
Mn content in liver0.60.72.40.21.20.1-1.4-0.10.21.50.0
Na content in liver0.10.10.2-0.4-0.00.3-0.1-0.40.50.00.4
Rb content in liver0.70.91.7-1.0-0.71.30.4-1.31.3-0.20.7
Se content in liver0.00.10.10.20.3-0.2-0.30.2-0.20.3-0.1
Sr content in liver0.30.30.80.6-0.0-0.50.10.5-0.5-0.1-0.9
Zn content in liver2.22.43.81.81.0-1.9-0.71.9-2.00.6-1.8